BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Colistin adjuvant-2 | Colistin adjuvant-2 is a colistin adjuvant. It shows increased colistin potentiation activity against Gram-negative bacteria. Molecular formula: C14H7Cl2F3N2O. Mole weight: 347.12. |  |
| Colitose | Colitose is an extensively applied biomedical compound renowned for its profound impact in studying colitis, a prevalent inflammatory bowel disease. Synonyms: 3,6-Dideoxy-L-xylo-hexose; L-Colitose. CAS No. 4221-05-0. Molecular formula: C6H12O4. Mole weight: 148.16. | |
| Collagen proline hydroxylase inhibitor | Collagen proline hydroxylase inhibitor is a collagen proline hydroxylase inhibitor; useful for antifibroproliferative agents. Synonyms: 1,10-Phenanthroline-3-carboxamide, N-ethyl-7,10-dihydro-8-nitro-7-oxo-N-propyl-. Grade: >98%. CAS No. 223666-07-7. Molecular formula: C18H18N4O4. Mole weight: 354.36. | |
| Collagen proline hydroxylase inhibitor-1 | Collagen proline hydroxylase inhibitor-1 is an antifibroproliferative agents. Synonyms: 1,10-Phenanthrolin-4(1H)-one, 3-nitro-8-[[4-(phenylmethyl)-1-piperazinyl]carbonyl]-. Grade: >98%. CAS No. 223663-32-9. Molecular formula: C24H21N5O4. Mole weight: 443.45. | |
| Colletobredin D | Colletobredin D is extracted from Colletotrichum aotearoa BCRC 09F0161, an endophytic fungus found in the leaves of an endemic Formosan plant Bredia oldhamii Hook. f. (Melastomataceae). CAS No. 1807808-70-3. Molecular formula: C22H34O8. Mole weight: 426.50. | |
| Colterol | Colterol, an impurity of Salbutamol, is used as a beta-adrenergic agonist, an anti-asthmatic drug and a bronchodilator agent. Uses: Β-adrenergic agonist. a metabolite of bitolterol. Synonyms: 4-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-1,2-benzenediol; (+/-)-α-[(tert-Butylamino)methyl]-3,4-dihydroxy-benzyl Alcohol; (+/-)-N-t-Butylnoradrenaline; (+/-)-tert-Butyl Noradrenaline; DL-1-(3,4-Dihydroxyphenyl)-2-tert-butylaminoethanol; DL-N-tert-Butylnorepinephrine; Salbutamol Impurity 27. Grade: ≥95%. CAS No. 18866-78-9. Molecular formula: C12H19NO3. Mole weight: 225.28. | |
| Colterol acetate | Colterol acetate is a short-acting β2-adrenoreceptor agonist. Bitolterol is the prodrug of Colterol used for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Synonyms: 4-(2-tert-Butylamino-1-hydroxyethyl)-benzene-1,2-diol acetate. CAS No. 10255-14-8. Molecular formula: C14H23NO5. Mole weight: 285.336. | |
| Colterol Hydrochloride | Colterol Hydrochloride, an impurity of Salbutamol, is used as a beta-adrenergic agonist, an anti-asthmatic drug and a bronchodilator agent. Synonyms: 4-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-1,2-benzenediol Hydrochloride; (+/-)-α-[(tert-Butylamino)methyl]-3,4-dihydroxy-benzyl Alcohol Hydrochloride; (+/-)-N-t-Butylnoradrenaline Hydrochloride; (+/-)-tert-Butyl Noradrenaline Hydrochloride; dl-1-(3,4-Dihydroxyphenyl)-2-tert-butylaminoethanol Hydrochloride; dl-N-tert-Butylnorepinephrine Hydrochloride. Grade: ≥95%. CAS No. 52872-37-4. Molecular formula: C12H20ClNO3. Mole weight: 261.74. | |
| Colupulone | Colupulone is a bitter acid extracted from HOPS. Synonyms: Colupulone; 468-27-9; BA8R555DNZ; NSC650561; UNII-BA8R555DNZ; 3,5-dihydroxy-2-isobutyryl-4,6,6-tris(3-methylbut-2-en-1-yl)cyclohexa-2,4-dien-1-one; 3,5-dihydroxy-4,6,6-tris(3-methylbut-2-en-1-yl)-2-(2-methylpropanoyl)cyclohexa-2,4-dien-1-one; 3,5-dihydroxy-4,6,6-tris(3-methylbut-2-enyl)-2-(2-methylpropanoyl)cyclohexa-2,4-dien-1-one; 2,4-Cyclohexadien-1-one, 3,5-dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(2-methyl-1-oxopropyl)-; I-BUTYROLUPUPHENONE; SCHEMBL316240; DTXSID80963664; CHEBI:136851; HY-N10867; NSC-650561; XC172848; CS-0637301; Q27458763; 3,5-dihydroxy-2-isobutyryl-4,6,6-tris(3-methyl-but-2-enyl)cyclohexa-2,4- dienone; 3,5-Dihydroxy-4-isobutyryl-2,6,6-tris-(3-methyl-but-2-enyl)-cyclohexa-2,4-dienone; 2,4-CYCLOHEXADIEN-1-ONE, 3,5-DIHYDROXY-4,6,6-TRIS(3-METHYL-2-BUTEN-1-YL)-2-(2-METHYL-1-OXOPROPYL)-; 3,5-dihydroxy-2,6,6-tris(3-methylbut-2-enyl)-4-(2-methylpropanoyl)cyclohexa-2,4-dien-1-one. Grade: > 95%. CAS No. 468-27-9. Molecular formula: C25H36O4. Mole weight: 400.56. | |
| Coluracetam | MKC-231 (10(-10)-10(-6) moll) significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholine mustard aziridinium ion (AF64A) treated rats, but not of normal rats. MKC-231 did not affect the AChE activity, [3H]- quinuclidinyl benzilate binding, and [3H]-pirenzepine binding. Oral administration of MKC-231 (1-10 mg/kg) significantly improved the learning deficits in the Morris' water maze of AF64A-treated rats, but it did not produce any significant side effects, like tremor, salivation or hypothermia, which were observed in rats treated with high doses of tacrine [1]. In acute behavioral experiments, MKC-231 and THA had no significant effect on AF64A-induced memory deficits at any doses tested (0.3, 1.0 and 3.0 mg/kg), whereas Dup 996, at a dose of 1.0 mg/kg, significantly improved memory deficits. In chronic experiments, MKC-231 improved memory deficit at all doses tested (0.3, 1.0, or 3.0 mg/kg p.o., once daily for 11 days) and Dup 996 did so only at a dose of 3.0 mg/kg, whereas THA did not improve memory deficit at any doses tested. Synonyms: Coluracetam; BCI-540; MKC-231; BCI 540; MKC 231; BCI540; MKC231. Grade: >98%. CAS No. 135463-81-9. Molecular formula: C19H23N3O3. Mole weight: 341.4. | |
| Combretastatin | Combretastatin is a dihydrostilbenoid that found in Combretum caffrum. Members of the combretastatin family shows varying ability to cause vascular disruption in tumors. Combretastatin can bind to the β-subunit of tubulin. It is a tubulin polymerisation inhibitor and can be used for the treatment of tumor. Uses: Tumor. Synonyms: COMBRETASTATIN; (R)-(-)-Combretastatin; (R)-3-Hydroxy-4-methoxy-α-(3,4,5-trimethoxyphenyl)benzeneethanol; 2-Methoxy-5-[(βR)-β-hydroxy-3,4,5-trimethoxyphenethyl]phenol; 5-[(R)-2-Hydroxy-2-(3,4,5-trimethoxyphenyl)ethyl]-2-methoxyphenol. Grade: 95%. CAS No. 82855-09-2. Molecular formula: C18H22O6. Mole weight: 337.37. | |
| Combretastatin A-1 | Combretastatin A1 is a cis-stilbene originally isolated from C. caffrum that inhibits microtubule assembly (ID50 = 2 μM) by binding to the colchicine binding site on β-tubulin. It inhibits proliferation of hepatocellular carcinoma (IC50s = 9.2-728.2 nM) and other carcinoma cell lines (IC50s = 12.2-2,247 nM). Combretastatin A1 increases apoptosis of HepG2 cells in a GSK3β-dependent manner by decreasing the levels of MCL-1 and β-catenin. Synonyms: Combretastatin A1; NSC-600032; (Z)-3-(3,4,5-trimethoxystyryl)-6-methoxybenzene-1,2-diol. Grade: 95%. CAS No. 109971-63-3. Molecular formula: C18H20O6. Mole weight: 332.35. | |
| Commendamide | Commendamide is a natural bacterial product which was discovered in a screen for commensal bacteria effector genes (Cbegs). Commendamide is structurally similar to long-chain N-acyl-amides, which commonly signal, in mammals, through G protein-coupled receptors. Commendamide activates GPR132 (also known as G2A) with an EC50 value of 11.8 μM. Synonyms: N-acyl-3-hydroxypalmitoyl-Glycine; 2-(3-hydroxyhexadecanoylamino)acetic acid. Grade: ≥95%. CAS No. 193825-78-4. Molecular formula: C18H35NO4. Mole weight: 329.5. | |
| Complement factor D-IN-2 | Complement factor D-IN-2, a complement factor D inhibitor, is used in the study of autoimmune diseases. Complement factor D-IN-2 targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. (Extracted from patent WO2015130838A1, compound 190). Synonyms: 2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)-; JYN42346; JYN 42346; JYN-42346. Grade: ≥95%. CAS No. 1903742-34-6. Molecular formula: C27H24BrN7O3. Mole weight: 574.43. | |
| Complex of α-D-Glucopyranosyl isomaltol 85% and α-D-Maltosyl isomaltol 15% | Complex of α-D-Glucopyranosyl isomaltol 85% and α-D-Maltosyl isomaltol 15%. Synonyms: Active hexose correlated compound; Complex of 1-[3-(α-D-Glucopyranosyloxy)-2-furanyl]-ethanone 85% and 1-[3-(4-O-α-D-Glucopyranosyl-α-D-glucopyranosyloxy)-2-furanyl]-ethanone 15%. Grade: ≥97%. Molecular formula: C12H16O8.C18H26O13. Mole weight: 450.39/288.25. | |
| Compound 10 | Compound 10 is a tool compound targeting the NFAT:AP-1 transcriptional complex on DNA. Synonyms: 2-(5-(1H-Benzo[d]imidazol-2-yl)pyridin-2-ylthio)-N-(3-acetamidophenyl)acetamide. Grade: 99%. CAS No. 841210-82-0. Molecular formula: C22H19N5O2S. Mole weight: 417.48. | |
| Compound 120 | Compound 120 is a partially deuterated analogue of Atazanavir, which is an oral HIV protease inhibitor. Compound 120 increases half life by approximately 50% in comparison with Atazanavir. Synonyms: Atazanavir-d15 sulfate. Grade: 99%. Molecular formula: C38H37D15N6O7.H2O4S. Mole weight: 818.03. | |
| Compound 1T-0216 | Compound 1T-0216 is a blocker of AKT1-FAK interaction, reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation. Synonyms: 1-(2-{[(2-methylbenzoyl)oxy]imino}cyclohexyl)-2,4-dinitrobenzene; [(1E)-2-(2,4-dinitrophenyl)cyclohexylidene]amino 2-methylbenzoate. CAS No. 383147-88-4. Molecular formula: C20H19N3O6. Mole weight: 397.39. | |
| Compound 1T-0219 (SC) | Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction which reduces the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation. Synonyms: [(1E)-2-(2,4-dinitrophenyl)cyclohexylidene]amino 4-methoxybenzoate; N-[2-(2,4-dinitrophenyl)cyclohexyliden]-N-[(4-methoxybenzoyl)oxy]amine; ZINC4085554. CAS No. 383147-92-0. Molecular formula: C20H19N3O7. Mole weight: 413.37. | |
| Compound 3344 hydrochloride | Compound 3344 hydrochloride is an inhibitor of KRAS-effector interaction with an affinity of 126 nm. Synonyms: 4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)-N-(3-((dimethylamino)methyl)phenyl)-2-methoxyaniline hydrochloride; Benzenemethanamine, 3-[[4-(2,3-dihydro-1,4-benzodioxin-5-yl)-2-methoxyphenyl]amino]-N,N-dimethyl-, hydrochloride (1:1); 3-[[4-(2,3-Dihydro-1,4-benzodioxin-5-yl)-2-methoxyphenyl]amino]-N,N-dimethylbenzenemethanamine hydrochloride; [4-(2,3-Dihydrobenzo[1,4]dioxin-5-yl)-2-methoxyphenyl][3-[(dimethylamino)methyl]phenyl]amine hydrochloride. Grade: ≥95%. CAS No. 2760889-75-4. Molecular formula: C24H26N2O3.HCl. Mole weight: 426.94. | |
| Compound 401 | Compound 401, a pyrimido-isoquinolinone compound, is a selective and cell-permeable inhibitor that has an reversible function on DNA-dependent protein kinase (DNA-PK). It is also a mammalian target of rapamycin (mTOR) with little affinity for 43 other com. Synonyms: 2-morpholin-4-ylpyrimido[2,1-a]isoquinolin-4-oneCompound 401; Compound-401; Compound401; 168425-64-72-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-oneCHEMBL1792422-Morpholin-4-yl-pyrimido[2,1-a]isoquinolin-4-oneSCHEMBL10092321CTK4D2994S-7713; S 7713; S77132-(morpholin-4-yl)pyrimido[2,1-a]iso. Grade: >99 %. CAS No. 168425-64-7. Molecular formula: C16H15N3O2. Mole weight: 281.31. | |
| Compound 43 TAO Kinase Inhibitor | Compound 43 TAO kinase inhibitor is an ATP-competitive and selective inhibitor of TAOK1 and TAOK2 (IC50s = 11 and 15 nM, respectively). It is selective for TAOK1 and TAOK2 over 62 kinases in a panel, but does inhibit TAOK3 by 87% and seven additional kinases by 21-52%. Synonyms: N-[2-oxo-2-[(1,2,3,4-tetrahydro-1-naphthalenyl)amino]ethyl]-[1,1'-biphenyl]-4-carboxamide. Grade: ≥98%. CAS No. 850467-66-2. Molecular formula: C25H24N2O2. Mole weight: 384.47. | |
| Compound 48/80 hydrochloride | Compound 48/80 is a condensation product of N-methyl-p-methoxyphenethylamine with formaldehyde that causes histamine degranulation from mast cells. Compound 48/80 also inhibits human platelet aggregation through suppression of calmodulin (CaM) (IC50 = 0.41 μg/ml for CaM-dependent Ca2+-transporter ATPase activity) and phospholipase C. Synonyms: 4-methoxy-3,5-bis[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-N-methyl-benzeneethanamine trihydrochloride. Grade: ≥95%. CAS No. 848035-21-2. Molecular formula: C32H45N3O3·3HCl. Mole weight: 629.1. | |
| Compound 56 | Compound 56 is a highly potent inhibitor of the epidermal growth factor receptor (EGFR; IC50 = 0.006 nM). It has been used to inhibit EGFR activity in pancreatic cancer cell lines and it can induce the differentiation of rat mesenchymal stem cells. Synonyms: N-(3-bromophenyl)-6,7-diethoxy-4-quinazolinamine. Grade: ≥95%. CAS No. 171745-13-4. Molecular formula: C18H18BrN3O2. Mole weight: 388.3. | |
| Compound E | Compound E is a cell-permeable inhibitor of γ-secretase (GSI), which is a multifunctional transmembrane protein complex enzymatically catalyzing the cleavage of single-pass transmembrane proteins. Compound E can inhibit Notch processing (IC50 = 2.2 nM in SupT1 cells) and β-ammyloid production in cell culture (IC50 = 0.3 nM). Synonyms: γ-Secretase Inhibitor; Gamma-Secretase Inhibitor XXI; (S,S)- 2-[2-(3,5-Difluorophenyl)-acetylamino]-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionamide; (2S)-2-{[(3,5-Difluorophenyl)acetyl]amino}-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide; N2-[(3,5-difluorophenyl)acetyl]-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-L-alaninamide. Grade: 98%. CAS No. 209986-17-4. Molecular formula: C27H24F2N4O3. Mole weight: 490.5. | |
| Compound W | Compound W, also called 3,5-bis(4-Nitrophenoxy)benzoic acid, a 3,3'-diiodothyronine sulfate cross-reactive substance, is an inhibitor of γ-secretase which causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25). Synonyms: 3,5-bis(4-Nitrophenoxy)benzoic acid; 173550-33-9; gamma-Secretase Modulator, CW; ACMC-1CUIP; SCHEMBL264541; CHEMBL1553155; CTK8B1007; JOSXKPZXMVHRKU-UHFFFAOYSA-; DTXSID10587892; JOSXKPZXMVHRKU-UHFFFAOYSA-N; HMS3269J17; ZINC2576957; ANW-22664; MFCD02093450; AKOS015833412; 3,5-bis (4-nitrophenoxy) benzoic acid; NCGC00167814-01; AJ-42568; AK-63150; EN002659; OR182673; KB-234083; TR-007681; B2120; Compound W|CW|3,5-Bis(4-nitrophenoxy)benzoic acid; BRD-K98143539-001-01-4; I14-62910. Grade: >98.0%(T)(HPLC). CAS No. 173550-33-9. Molecular formula: C19H12N2O8. Mole weight: 396.31. | |
| Compound Y-1 | Compound Y-1 is a neuraminidase inhibitor with IC50 of 0.21 μM. Compound Y-1 exhibits activity against H1N1 influenza virus. Synonyms: Neuraminidase-IN-1; Y-1. Grade: 99.22%. CAS No. 2379438-80-7. Molecular formula: C14H11N3O6. Mole weight: 317.25. | |
| Conantokin-G | Conantokin-G is a conopeptide that has been isolated from the venom of the cone Conus geographus. Conantokin-G selectively inhibits NR2B containing N-methyl-D-aspartate receptors (NMDAR) with a high specificity. Uses: Excitatory amino acid antagonists. Synonyms: Conotoxin GV; Conotoxin G V; Sleeper peptide; Conantokin G; Conotoxin G V; GEXXLQXNQX LIRXKSN; H-Gly-Glu-Gla-Gla-Leu-Gln-Gla-Asn-Gln-Gla-Leu-Ile-Arg-Gla-Lys-Ser-Asn-NH2. Grade: > 94.5 %. CAS No. 93438-65-4. Molecular formula: C88H138N26O44. Mole weight: 2264.23. | |
| Conduritol B epoxide | Conduritol B epoxide (CBE) is an irreversible inhibitor of covalently bound acid β-glucosidase, also known as GBA, or GBA1 (IC50 = 9 μM). It also does not inhibit non-lysosomal glucosylceramidase or cytosolic β-glucosidase. Synonyms: CBE; 1,2-anhydro-myo-inositol. Grade: ≥95%. CAS No. 6090-95-5. Molecular formula: C6H10O5. Mole weight: 162.1. | |
| Conduritol D | Conduritol D is a versatile and essential compound in the dynamic compound realm, taking center stage in the research of metabolic disorders. This valuable compound exhibits unmatched proficiency as a foundational unit for synthesizing carbohydrate-based pharmaceuticals. Synonyms: (1R,2R,3S,4S)-rel-5-cyclohexene-1,2,3,4-tetrol. CAS No. 4782-75-6. Molecular formula: C6H10O4. Mole weight: 146.14. | |
| Conessine | Conessine is a naturally occurring steroidal dibasic alkaloid with a rigid steroid-based skeleton. It is found in a number of plant species from the apocynaceae family. It is a selective, specific and potent histamine H3 receptor antagonist. It has high selectivity for both rat and human histamine H3 receptors. It has a poor rate of CNS clearance. It also binds to the human α2C4 adrenergic receptor. It has anti-malarial activity and displays in vitro antiplasmodial activity. It is used as a treatment for amoebic dysentery. It was developed by Abbott. Synonyms: Conessine; Conessinum; Konessin; Neriine; Roquessine; Wrightine; (3R,3aR,5aR,5bR,9R,11aS,11bR,13aR)-N,N,2,3,11a-pentamethyl-2,3,3a,4,5,5a,5b,6,8,9,10,11,11a,11b,12,13-hexadecahydro-1H-naphtho[2',1':4,5]indeno[1,7a-c]pyrrol-9-amine; (3β)-N,N-dimethyl-con-5-enin-3-amine; NSC 119994; Neriine; Roquessine; Wrightine; N,18-Dihydrotrimethylconkurchine; (+)-Conessine; N',18-Dihydro-N,N,N'-trimethylconkurchine; (3β)-N,N-Dimethylcon-5-enin-3-amine; 3β-(Dimethylamino)con-5-enine; N,N-Dimethyl-con-5-enin-3-amine. CAS No. 546-06-5. Molecular formula: C24H40N2. Mole weight: 356.59. | |
| Conglobatin B | Conglobatin B is a bacterial metabolite produced by the strain of Streptomyces MST-91080 and has anticancer activity. It is cytotoxic to NS-1 mouse myeloma cells (IC50 = 0.084 μg/ml) but not NFF human fibroblasts (IC50 = >100 μg/ml). Synonyms: 3E,5R,7S,11E,15S-pentamethyl-8S,16S-bis(oxazol-5-ylmethyl)-1,9-dioxacyclohexadeca-3,11-diene-2,10-dione. Grade: >95% by HPLC. Molecular formula: C27H36N2O6. Mole weight: 484.58. | |
| Conglobatin C | Conglobatin C is a formidable organic compound extracted from Conglobatin plant species, demonstrating unrivaled potential in thwarting the proliferation and expansion of an array of cancerous cell types. Synonyms: Conglobatin C11111. Grade: >95% by HPLC. Molecular formula: C26H34N2O6. Mole weight: 470.56. | |
| Congo Red | Congo Red is an acid secondary azo dye. It is a VGlut inhibitor and could decrease synaptic transmission in the dentate gyrus. It is an amyloid fibril-binding dye. It can be used to diagnose amyloidosis and used as a diagnostic test for the presence of amyloid in tissue sections. It inhibits the pancreatic islet cell toxicity of diabetes-associated amylin. Its excitation wavelength is 497 nm. It is also a general tissue stain for use as a cytoplasmic counterstain. It is also used in testing for hydrochloric acid in gastric contents and used to stain β sheet aggregates. Synonyms: 1-Naphthalenesulfonic acid, 3,3'-[[1,1'-biphenyl]-4,4'-diylbis(2,1-diazenediyl)]bis[4-amino-, sodium salt (1:2); 1-Naphthalenesulfonic acid, 3,3'-[[1,1'-biphenyl]-4,4'-diylbis(azo)]bis[4-amino-, disodium salt; C.I. Direct Red 28, disodium salt; Atlantic Congo Red; Atul Congo Red; Azocard Red Congo; Benzo Congo Red; Brasilamina Congo 4B; C.I. 22120; C.I. Direct Red 28; Congo red disodium salt; Cotton Red L; Diacotton Congo Red; Direct Congo Red; Erie Congo 4B; Haemomedical; Haemonorm; Hemorrhagyl; Kayaku Congo Red; Mitsui Congo Red; Peeramine Congo Red; Red K (dye); Solucongo; Sugai Congo Red; Tertrodirect Red C; Trisulfon Congo Red; Vondacel Red CL. Grade: ≥98% by HPLC. CAS No. 573-58-0. Molecular formula: C32H22N6Na2O6S2. Mole weight: 696.66. | |
| Coniine hydrobromide | Coniine hydrobromide is a polyketide-derived alkaloid that is toxic to humans and animals. It is a nicotinic acetylcholine receptor antagonist that causes inhibition of the nervous system. Synonyms: Piperidine, 2-propyl-, hydrobromide (1:1), (2S)-; Piperidine, 2-propyl-, moohydrobromide, (2S)-; Piperidine, 2-propyl-, hydrobromide, (S)-; (S)-Coniine hydrobromide; (+)-Coniine hydrobromide; (S)-(+)-Coniine hydrobromide; (S)-2-Propylpiperidine hydrobromide. Grade: ≥95%. CAS No. 637-49-0. Molecular formula: C8H17N.HBr. Mole weight: 208.14. | |
| Coniine hydrochloride | Coniine hydrochloride is a polyketide-derived alkaloid that is toxic to humans and animals. It is a nicotinic acetylcholine receptor antagonist that causes inhibition of the nervous system. Synonyms: Piperidine, 2-propyl-, hydrochloride (1:1), (2S)-; Piperidine, 2-propyl-, monohydrochloride, (2S)-; Piperidine, 2-propyl-, hydrochloride, (S)-; (+)-Coniine hydrochloride; (S)-(+)-Coniine hydrochloride; (S)-2-Propylpiperidine hydrochloride; (S)-Coniine hydrochloride; NSC 15128. Grade: ≥95%. CAS No. 555-92-0. Molecular formula: C8H17N.HCl. Mole weight: 163.69. | |
| Conivaptan | Conivaptan, also called as YM 087 or Vaprisol, is the first is a non-peptide inhibitor of antidiuretic hormone (vasopressin receptor antagonist) approved by United States Federal Drug Administrations (FDA) for the treatment of hyponatremia. Synonyms: [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-; N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl][1,1'-biphenyl]-2-carboxamide; ZINC 12503187; N-(4-(2-methyl-3,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide. Grade: 95%. CAS No. 210101-16-9. Molecular formula: C32H26N4O2. Mole weight: 498.58. | |
| Conivaptan-d4 | Conivaptan-d4 is a labelled Conivaptan. Conivaptan is an arginine vasopressin (AVP) receptor inhibitor approved for the treatment of decompensated congestive heart failure. Grade: > 95%. CAS No. 1129433-63-1. Molecular formula: C32H22N4O2D4. Mole weight: 502.61. | |
| Conivaptan hydrochloride | Conivaptan HCl is a non-peptide inhibitor of antidiuretic hormone (vasopressin receptor antagonist). Uses: Antidiuretic hormone receptor antagonists. Synonyms: N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-Biphenyl]-2-carboxamide Hydrochloride; Vaprisol; YM 087; [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, hydrochloride (1:1); [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, monohydrochloride; Conivaptan monohydrochloride. Grade: >98%. CAS No. 168626-94-6. Molecular formula: C32H26N4O2.HCl. Mole weight: 535.04. | |
| Conivaptan hydrochloride Impurity D | Conivaptan hydrochloride Impurity D is an impurity of Conivaptan hydrochloride, a therapeutic agent instrumental in rectifying specific fluid and electrolyte disturbances. CAS No. 168626-74-2. | |
| Conivaptan hydrochloride Impurity E | Conivaptan hydrochloride Impurity E is an impurity of Conivaptan hydrochloride, a drug for treatig an array of medical afflictions, encompassing acute hyponatremia and congestive heart failure. CAS No. 877858-27-0. | |
| Conivaptan hydrochloride Impurity G | Conivaptan hydrochloride Impurity G acts as an impurity in conivaptan hydrochloride, a medication used to manage euvolemic and hypervolemic hyponatremia in hospitalized patients. CAS No. 168626-93-5. | |
| Conivaptan hydrochloride Impurity H | Conivaptan Hydrochloride Impurity H is an impurity of Conivaptan Hydrochloride, presenting as a pivotal therapeutic intervention for a heterogeneous spectrum of afflictions encompassing heart failure, hyponatremia and liver cirrhosis. Operating diligently as a potent inhibitor, Conivaptan Hydrochloride orchestrates the regulation of arginine vasopressin, efficaciously fostering diuresand reinstating homeostasis pertaining to electrolyte equilibrium within the corporeal domain. Synonyms: 4-bromo-1-[(4-methylphenyl)sulfonyl]-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one; 4-bromo-1-(4-methylphenyl)sulfonyl-3,4-dihydro-2H-1-benzazepin-5-one; 4-BROMO-1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE; 4-bromo-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one; 5H-1-Benzazepin-5-one, 4-bromo-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-; Conivaptan hydrochloride Impurity H; NSC140796; SCHEMBL19149798; DTXSID40301048; BCP18303; NSC-140796; F19329; A899571; AN-975/13811041. CAS No. 29489-04-1. Molecular formula: C17H16BrNO3S. Mole weight: 394.3. | |
| Conivaptan hydrochloride Impurity I | Conivaptan hydrochloride Impurity I is an impurity encountered in Conivaptan hydrochloride. Conivaptan hydrochloride is an extensively employed pharmaceutical agent efficacious in treating hyponatremia as well as fluid retention linked with congestive heart failure and hepatic ailments. CAS No. 717917-14-1. | |
| Conjugated estrogens | Conjugated estrogens is a complex mixture of sodium estrone sulfate and sodium equilin sulfate derived synthetically from estrone and equilin or extracted from pregnant mares' urine. Uses: Estrogens. Synonyms: Estrogens, conjugated; Estrogens, conjugates (12C); Ayerogen; Ayerogen Crema Vaginal; Azumon; C.E.S.; Cenestin; Climarest; Conjugated equine estrogen; Conjugates, estrogens; Conjugen; Dagynil; Emopremarin; Equin; Femavit; Hyphorin; Mannest; Menopak E; Menpoz; Neo-Menovar; Oestro-Feminal; Ovest; Premaril; Premarin; Premarin Crema V; Premarin Creme; Premarin Vaginal Creme; Premarina; Premarose; Presomen; Prevagin-Premaril; Romeda; Sefac; Srogen; Sukingpo; Transannon. Grade: 95%. CAS No. 12126-59-9. Molecular formula: C18H19NaO5S. Mole weight: 370.4. | |
| Conoidin A | Peroxiredoxins are a ubiquitous family of antioxidant enzymes that also control cytokine-induced peroxide levels and thereby mediate signal transduction in mammalian cells. Conoidin A inactivates peroxiredoxins by covalently binding to the catalytic cysteine on the enzyme. It has been shown to inhibit peroxiredoxin II (IC50 = 23 μM) in the parasite T. gondii and peroxiredoxin I in the hookworm A. ceylanicum. Synonyms: 2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide. Grade: ≥98%. CAS No. 18080-67-6. Molecular formula: C10H8Br2N2O2. Mole weight: 348. | |
| Conquinine | Conquinine is a Cytochrome P450 2D6 inhibitor. It is a dextrorotatory stereoisomer of quinine extracted from the bark of the Cinchona tree and similar plant species. It is an alkaloid with class 1A antiarrhythmic and antimalarial effects. It also blocks muscarinic and alpha-adrenergic neurotransmission. It stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thus inhibiting the sodium influx required for the initiation and conduction of impulses resulting in an increase of the threshold for excitation and decreased depolarization during phase 0 of the action potential. It acts primarily as an intra-erythrocytic schizonticide through association with the heme polymer (hemazoin) in the acidic food vacuole of the parasite thereby preventing further polymerization by heme polymerase enzyme. Uses: Conquinine is an alkaloid with class 1a antiarrhythmic and antimalarial effects. it also blocks muscarinic and alpha-adrenergic neurotransmission. Synonyms: Quinidine; Chinidin; Pitayine; (+)-Quinidine; Quinidex; Chinidin; (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol. Grade: 98%. CAS No. 56-54-2. Molecular formula: C20H24N2O2. Mole weight: 324.42. | |
| Conteltinib | Conteltinib is a multikinase inhibitor that targets FAK, ALK and Pyk2 and has a significant inhibitory effect on FAK with an IC50 of 1.6 nM. Uses: Protein kinase inhibitors. Synonyms: CT-707; Benzenesulfonamide, 2-[[6,7-dihydro-2-[[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-N-(1-methylethyl)-. Grade: ≥95%. CAS No. 1384860-29-0. Molecular formula: C32H45N9O3S. Mole weight: 635.82. | |
| Contezolid | Contezolid is a new and orally active oxazolidinone. It is an antibiotic in study for complicated skin and soft tissue infections (cSSTI) caused by resistant Gram-positive bacteria. Contezolid markedly reduces potential for myelosuppression and monoamine oxidase inhibition (MAOI). Synonyms: MRX-I; Lascufloxacin; (S)-5-((isoxazol-3-ylamino)methyl)-3-(2,3,5-trifluoro-4-(4-oxo-3,4-dihydropyridin-1(2H)-yl)phenyl)oxazolidin-2-one. CAS No. 1112968-42-9. Molecular formula: C18H15F3N4O4. Mole weight: 408.33. | |
| Copanlisib | Copanlisib is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. BAY 80-6946 inhibits the activation of the PI3K signaling pathway, which may result in the inhibition of tumor cell growth and survival in susceptible tumor cell populations. Synonyms: BAY 80-6946; Aliqopa; BAY-80-6946; 2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide. Grade: ≥98%. CAS No. 1032568-63-0. Molecular formula: C23H28N8O4. Mole weight: 480.529. | |
| copanlisib hydrochloride | Copanlisib hydrochloride is a potent inhibitor of Class I phosphoinositide 3-kinase which showed a therapeutic effect on non-Hodgkin lymphoma. It was approved to treat follicular lymphoma that has relapsed after treatment with at least two other anticancer therapies. Uses: The potential treatment of non-hodgkin lymphoma. Synonyms: BAY 80-6946 dihydrochloride; BAY 80 6946 dihydrochloride; BAY 806946 dihydrochloride; Copanlisib hydrochloride; Aliqopa; Copanlisib dihydrochloride; UNII-03ZI7RZ52O; 03ZI7RZ52O; BAY 80-6946 dihydrochloride; BAY-80-6946 dihydrochloride. CAS No. 1402152-13-9. Molecular formula: C23H30Cl2N8O4. Mole weight: 553.445. | |
| CoPo 22 | CoPo 22 is a corrector and potentiator for ?F508-cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel function in cystic fibrosis. Synonyms: CoPo 22; CoPo22; CoPo-22; ASN 06744166; ASN06744166; ASN-06744166; N-(2-((3-Cyano-5,7-dimethylquinolin-2-yl)amino)ethyl)-3-methoxybenzamide; N-[2-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]ethyl]-3-methoxybenzamide. Grade: 99%. CAS No. 606101-83-1. Molecular formula: C22H22N4O2. Mole weight: 374.44. | |
| COR 170 | COR 170 has been found to be an inverse agonist of CB2 receptors and could be used in studies for CB1 and CB2 receptor affinity. Synonyms: COR-170; COR 170; COR170; N-(Adamant-1-yl)-4-oxo-1-pentyl-6-phenyl-1,4-dihydroquinoline-3-carboxamide. Grade: ≥99% by HPLC. CAS No. 1048039-15-1. Molecular formula: C31H36N2O2. Mole weight: 468.63. | |
| Corin | Corin is a histone lysine specific demethylase (LSD1) and histone deacetylase (HDAC) dual inhibitor, with a Ki(inact) of 110 nM for LSD1 and an IC50 of 147 nM for HDAC1. Synonyms: 4-[4-({4-[(1S,2R)-2-Aminocyclopropyl]phenyl}amino)-4-oxobutyl]-N-(2-aminophenyl)benzamide; Benzenebutanamide, N-[4-[(1R,2S)-2-aminocyclopropyl]phenyl]-4-[[(2-aminophenyl)amino]carbonyl]-, rel-. Grade: ≥98%. CAS No. 1808113-09-8. Molecular formula: C26H28N4O2. Mole weight: 428.53. | |
| CORM-3 | CORM-3 is a water-soluble carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity. It attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels. Synonyms: Tricarbonylchloro(glycinato)ruthenium; (OC-6-44)-Tricarbonylchloro(glycinato-κN,κO)ruthenium; CORM3; CORM 3. Grade: >98%. CAS No. 475473-26-8. Molecular formula: C5H4ClNO5Ru. Mole weight: 294.61. | |
| Coronastat | Coronastat is a potent inhibitor of the SARS-CoV-2 3CL protease. Coronastat represents a new candidate for a small molecule protease inhibitor for the treatment of SARS-CoV-2 infection for eliminating pandemics involving coronaviruses. Synonyms: NK01-63. CAS No. 2922281-15-8. Molecular formula: C22H29F3N3NaO8S. Mole weight: 575.53. | |
| Cortagine | Cortagine is a selective and potent corticotrophin releasing factor receptor 1 (CRF1) agonist with EC50 value of 0.18 nM for rat CRF1. It shows antidepressant and anxiolytic activity in the mouse model. Synonyms: cortagine; DC41887. Molecular formula: C192H323N55O63S. Mole weight: 4442.06. | |
| Cortexolone 17 alpha-propionate | Cortexolone 17 alpha-propionate, also called as CB-03-01, belonging to the family of ester derivatives of cortexolone, is a potent and topical and peripherally selective steroid antagonist of androgen. Synonyms: CB-03-01; CB 03-01; CB03-01; [(8R,9S,10R,13S,14S,17R)-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoateCB-03-01cortexolone 17alpha-propionate. CAS No. 19608-29-8. Molecular formula: C24H34O5. Mole weight: 402.52. | |
| Corticosterone | Extract from the adrenal cortex, is a sensitive inhibitor of monoamine transport. Uses: A sensitive inhibitor of monoamine transport. Synonyms: Corticosterone; BRN 2339601; BRN-233960; BRN233960; CCRIS 6753; CCRIS-6753; CCRIS6753; NSC 9705; NSC-9705; NSC9705; (8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one. Grade: ≥98%. CAS No. 50-22-6. Molecular formula: C21H30O4. Mole weight: 346.46. | |
| Corticotropin-releasing factor | Corticotropin-Releasing Factor (CRF) is a neuropeptide of utmost significance is assumes a pivotal role in the intricate regulation of the physiological stress response. Synonyms: ACTH-releasing factor; ACTH-releasing hormone; Corticoliberin; Corticotropin-releasing activity; Corticotropin-releasing hormone; CRF; CRF (hormone). Grade: 95%. CAS No. 9015-71-8. | |
| Corticotropin Releasing Factor Antagonist | Corticotropin Releasing Factor Antagonist is a groundbreaking biomedical compound, meticulously aiming to modulate the intricacies of the enigmatic Corticotropin Releasing Factor (CRF) system. Synonyms: alpha-Helical CRF (9-41); Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Met-Leu-Glu-Met-Ala-Lys-Ala-Glu-Gln-Glu-Ala-Glu-Gln-Ala-Ala-Leu-Asn-Arg-Leu-Leu-Leu-Glu-Glu-Ala-NH2; α-Helical corticotropin releasing factor fragment (9-41). Grade: ≥97% by HPLC. CAS No. 99658-03-4. Molecular formula: C166H274N46O53S2. Mole weight: 3826.36. | |
| Cortisone-d2 | Cortisone-d2 is a labelled Cortisone. Cortisone is a natural glucocorticoid used as an anti-inflammatory drug. Synonyms: 4-Pregnen-17α,21-diol-3,11,20-trione-1,2-d2. Grade: > 95%. Molecular formula: C21H26O5D2. Mole weight: 362.46. | |
| Cortistatin 14, human, rat acetate | Cortistatin 14 is an endogenous neuropeptide similar to somatostatin-14 in structure and function. It is mainly expressed in the cortex and hippocampus. It shows potency at all somatostatin receptors, but prevents somatostatin-14 binding. It binds to the growth hormone secretagog receptor (GHS-R1a). It displays sleep-modulating and neuronal depressant properties in vivo. Synonyms: CST-14, human, rat acetate. Molecular formula: C83H117N19O21S2. Mole weight: 1781.1. | |
| Cortistatin-14 trifluoroacetate salt | Cortistatin-14 (TFA) is a neuropeptide which is structural similar to somatostatin-14 and it binds and exerts its function via the somatostatin receptors (sst1-sst5). Cortistatin-14 (TFA) shows anticonvulsive, neuroprotective effect and remarkable anti-inflammatory properties. Cortistatin-14 is an endogenous neuropeptide agonist of somatostatin receptors (IC50s = 0.5-18.2 nM for human SST1-SST5 receptors expressed in CCL39 cells). Grade: ≥95%. Molecular formula: C81H113N19O19S2·xCF3COOH. Mole weight: 1721.01. | |
| Cortodoxone | Cortodoxone, a glucocorticoid receptor antagonist, is an intermediate which can be oxygenated to cortisol. Uses: Glucocorticoid receptor binding. Synonyms: (8R,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one 11 Deoxycortisol 11 Desoxycortisol 11 Desoxycortisone 11-Deoxycortisol 11-Desoxycortisol 11-Desoxycortisone Cortexo. Grade: >98.0%(LC). CAS No. 152-58-9. Molecular formula: C21H30O4. Mole weight: 346.46. | |
| Cosan 528 | Cosan-528 is a fungicide which is active against the fungus A. pullulans (MIC = 8 ppm). Cosan-528 completely inhibits the growth of A. pullulans, A. niger, and Penicillium on paint-coated white pine sapwood for at least six weeks. Synonyms: Cosan-528; Cosan528; 2-Chloro-N-(2-methyl-4-bromophenyl)acetamide. CAS No. 96686-51-0. Molecular formula: C9H9BrClNO. Mole weight: 262.54. | |
| COTI-2 | COTI-2 is an p53 gene activator and the PI3K/AKT/mTOR pathway inhibitor. COTI-2 induces apoptosis and suppresses proliferation of a wide variety of human cancer cell lines in vitro. Synonyms: COTI-2; COTI2; COTI 2. 2BTA1O65BR; ZINC114475331; CS-8156; CS 8156; CS8156; N-[(E)-6,7-dihydro-5H-quinolin-8-ylideneamino]-4-pyridin-2-ylpiperazine-1-carbothioamide. Grade: 99%. CAS No. 1039455-84-9. Molecular formula: C19H22N6S. Mole weight: 366.48. | |
| COTI 219 | COTI 219 is an oral small-molecule inhibitor of the KRAS mutant form, without affecting normal KRAS function. Synonyms: COTI-219; 4-Methyl-1-piperazinecarbothioic Acid 2-(9H-Cyclopenta[1,2-b:4,3-b']dipyridin-9-ylidene)hydrazide. CAS No. 1039455-85-0. Molecular formula: C17H18N6S. Mole weight: 338.43. | |
| Cot inhibitor-1 | Cot inhibitor-1 is a COT/Tpl2 inhibitor. Synonyms: 3-Quinolinecarbonitrile, 8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[[[1-[2-(hexahydro-1H-azepin-1-yl)ethyl]-1H-1,2,3-triazol-4-yl]methyl]amino]-. Grade: >98%. CAS No. 915365-57-0. Molecular formula: C27H27Cl2FN8. Mole weight: 553.46. | |
| Cot inhibitor-2 | Cot inhibitor-2 is a COT/Tpl2 inhibitor. Synonyms: 3-Quinolinecarbonitrile, 8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[[[1-(1-ethyl-4-piperidinyl)-1H-1,2,3-triazol-4-yl]methyl]amino]-. Grade: >98%. CAS No. 915363-56-3. Molecular formula: C26H25Cl2FN8. Mole weight: 539.43. | |
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