BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| CKI-7 free base | CKI-7 free base is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC50 of 6 μM and a Ki of 8.5 μM. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). Uses: Found to have a potent inhibitory action against casein kinase 1 completely with respect to atp and a much weaker effect on casein kinase 2 and other protein kinases. Synonyms: CKI-7; CKI 7; 8-Isoquinolinesulfonamide, N-(2-aminoethyl)-5-chloro-. Grade: 95%. CAS No. 120615-25-0. Molecular formula: C11H12ClN3O2S. Mole weight: 285.75. |  |
| c-Kit-IN-2 | c-Kit-IN-2 is a c-Kit inhibitor with an IC50 of 82 nM, and has good antiproliferative activity against all the three GIST cell lines, GIST882, GIST430, and GIST48, with GI50s of 3, 1 and 2 nM, respectively. Synonyms: 1-(5-Ethyl-1,2-oxazol-3-yl)-3-[4-(2-{[6-(4-ethyl-1-piperazinyl)-4-pyrimidinyl]amino}-1,3-thiazol-5-yl)phenyl]urea; Urea, N-(5-ethyl-3-isoxazolyl)-N'-[4-[2-[[6-(4-ethyl-1-piperazinyl)-4-pyrimidinyl]amino]-5-thiazolyl]phenyl]-. Grade: ≥95%. CAS No. 2121515-37-3. Molecular formula: C25H29N9O2S. Mole weight: 519.62. | |
| c-Kit-IN-3 | c-Kit-IN-3 is a selective inhibitor of c-KIT kinase. c-Kit-IN-3 displays great potencies against most of the gain-of function mutations in the juxtamembrane domain, drugresistant mutations in the ATP binding pocket, and activation loops. Synonyms: c-Kit IN 3; c-Kit IN-3; c-Kit-IN 3. CAS No. 2363169-01-9. Molecular formula: C26H20ClF3N2O4. Mole weight: 516.90. | |
| CL075 | CL075 is a thiazoloquinolone derivative that stimulates TLR8 in human peripheral blood mononuclear cells. Uses: Toll-like receptor agonists. Synonyms: CL 075; CL-075; Thiazolo[4,5-c]quinolin-4-amine, 2-propyl-; 2-Propylthiazolo[4,5-c]quinolin-4-amine; 3M 002; 3M-002; 3M002. Grade: ≥95%. CAS No. 256922-53-9. Molecular formula: C13H13N3S. Mole weight: 243.33. | |
| CL097 | CL097 is a human TLR7/8 and mouse TLR7 agonist. Synonyms: CL 097; CL-097; 3H-Imidazo[4,5-c]quinolin-4-amine, 2-(ethoxymethyl)-; 2-(Ethoxymethyl)-1H-imidazo[4,5-C]quinolin-4-amine. Grade: ≥95%. CAS No. 1026249-18-2. Molecular formula: C13H14N40. Mole weight: 242.28. | |
| CL 218872 | CL 218872 has been found to be a benzodiazepine agonist and has been found to exhibit anxiolytic and anticonvulsant activities. Synonyms: CL 218872; CL218872; CL-218872; 3-Methyl-6-[-3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine. Grade: ≥99% by HPLC. CAS No. 66548-69-4. Molecular formula: C13H9F3N4. Mole weight: 278.24. | |
| CL264 | CL264 is a small-molecule agonist of TLR7. Synonyms: Glycine, N-[4-[[6-amino-2-(butylamino)-7,8-dihydro-8-oxo-9H-purin-9-yl]methyl]benzoyl]-; N-[4-[[6-Amino-2-(butylamino)-7,8-dihydro-8-oxo-9H-purin-9-yl]methyl]benzoyl]glycine; CL 246; CL 264; CL-264; (4-((6-amino-2-(butylamino)-8-oxo-7,8-dihydro-9H-purin-9-yl)methyl)benzoyl)glycine. Grade: ≥95%. CAS No. 1510712-69-2. Molecular formula: C47H73N13O7S. Mole weight: 413.43. | |
| CL2-MMT-SN38 | CL2-MMT-SN38 is a derivative of SN-38, an anticancer drug that is an active metabolite of the topoisomerase I inhibitor Irinotecan. Synonyms: 4-((2S,5S)-5-benzyl-38-(4-((4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexane-1-carboxamido)methyl)-1H-1,2,3-triazol-1-yl)-2-(4-(((4-methoxyphenyl)diphenylmethyl)amino)butyl)-4,7,11-trioxo-9,15,18,21,24,27,30,33,36-nonaoxa-3,6,12-triazaoctatriacontanamido)benzyl ((S)-4,11-diethyl-9-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl) carbonate. Grade: ≥90%. CAS No. 1084888-82-3. Molecular formula: C102H122N12O24. Mole weight: 1900.13. | |
| CL307 | CL307 is an agonist of TLR7. Synonyms: Benzamide, 4-[[6-amino-2-(butylamino)-7,8-dihydro-8-oxo-9H-purin-9-yl]methyl]-N-[2-[[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]amino]-2-oxoethyl]-; CL 307; CL-307; N1-glycinyl[4-((6-amino-2-(butylamino)-8-hydroxy-9H-purin-9-yl)methyl)benzoyl]spermine; 4-((6-amino-2-(butylamino)-8-oxo-7,8-dihydro-9H-purin-9-yl)methyl)-N-(2-((3-((4-((3-aminopropyl)amino)butyl)amino)propyl)amino)-2-oxoethyl)benzamide; 4-[[6-Amino-2-(butylamino)-7,8-dihydro-8-oxo-9H-purin-9-yl]methyl]-N-[2-[[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]amino]-2-oxoethyl]benzamide. Grade: ≥95%. CAS No. 1548551-79-6. Molecular formula: C29H47N11O3. Mole weight: 597.76. | |
| CL-316243 | CL-316243 is a potent and highly selective β3-adrenoceptor agonist (EC50 = 3 nM) with > 10000-fold selective over β1 and β2 receptors. CL 316243 possesses anti-obesity and anti-diabetic effects due to increasing brown adipose tissue thermogenesis and metabolic rate, and consequently may be useful for treating obesity as well as non-insulin-dependent diabetes mellitus in obese persons, without causing excessive side effects. Synonyms: CL-316243; CL 316243; CL316243; 5-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate; 138908-40-4 (CL-316243 sodium). Grade: >98%. CAS No. 183720-02-7. Molecular formula: C20H20ClNNa2O7. Mole weight: 419.794. | |
| CL 316243 disodium salt | The sodium salt form of CL 316243, which has been found to be a β3-adrenoceptor agonist and could probably decrease blood insulin as well as glucose levels. Synonyms: CL 316243 disodium salt; CL316243 disodium salt; CL-316243 disodium salt; 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylic acid disodium salt. Grade: ≥98% by HPLC. CAS No. 151126-84-0. Molecular formula: C20H18ClNNa2O7. Mole weight: 465.80. | |
| CL-316243 sodium | CL-316243 is a highly selective β3-adrenoceptor agonist with EC50 value of 3 nM; > 10000-fold selective over β1 and β2 receptors. CL-316243 can restore the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice and enhance insulin-stimulated glucose disposal in nonobese rats. Preclical trials for the treatment of Obesity, Overactive bladder and Type 2 diabetes mellitus were discontinued. Uses: Obesity; overactive bladder; type 2 diabetes mellitus. Synonyms: CL-316243 sodium; CL 316243 sodium; CL316243 sodium; disodium; 5-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate; BTA 243; HP 186; BTA243; HP186; BTA-243; HP-186. Grade: 98%. CAS No. 138908-40-4. Molecular formula: C20H18ClNNa2O7. Mole weight: 465.79. | |
| CL-387785 | CL-387785, also known as EKI-785, is an irreversible inhibitor of EGF-receptor (EGFR) kinase activity in vivo (IC50 = 250-490 pM). CL-387785 covalently bound to EGF-R. It also specifically inhibited kinase activity of the protein (IC50 = 370+/-120 pM), blocked EGF-stimulated autophosphorylation of the receptor in cells (ic50 approximately 5 nM), inhibited cell proliferation (IC50 = 31-125 nM) primarily in a cytostatic manner in cell lines that overexpress EGF-R or c-erbB-2, and profoundly blocked the growth of a tumor that overexpresses EGF-R in nude mice (when given orally at 80 mg/kg/day for 10 days, daily). CL-387,785 is useful for studying the interaction of small molecules with EGF-R and may have clinical utility. Uses: Protein kinase inhibitors. Synonyms: CL-387785; CL 387785; CL-387,785; CL387785; EKI-785; EKI 785; EKI785. Grade: 0.98. CAS No. 194423-06-8. Molecular formula: C18H13BrN4O. Mole weight: 381.233. | |
| CL 43356 | CL 43356 is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: CL 43356; CL 43356; CL 43356; CL-43,356; O,O-dimethyl 1,3-dithiolan-2-ylidenephosphoramidothioate; N-dimethoxyphosphinothioyl-1,3-dithiolan-2-imine. Grade: ≥98%. CAS No. 3572-55-2. Molecular formula: C5H10NO2PS3. Mole weight: 242.96. | |
| Cl-4AS-1 | Cl-4AS-1 is a mouse mammary tumor virus (MMTV) promoter and represses MMP1 promoter activity. It also inhibits 5α-Reductase type I and II with IC50 values of 6 and 10 nM respectively, as well as is a potent steroidal androgen receptor agonist with IC50 value of 12 nM. It mimics the action of 5α-dihydrotestosterone (DHT). Synonyms: (4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)-N-(2-Chlorophenyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1,4,6a-trimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide. Grade: ≥99% by HPLC. CAS No. 188589-66-4. Molecular formula: C26H33ClN2O2. Mole weight: 441.01. | |
| CL5D | CL5D is a SIRT6 activator which activates SIRT6 deacetylase activity. Grade: >98%. CAS No. 2488745-53-3. Molecular formula: C29H11Cl7N2O6. Mole weight: 731.57. | |
| CL 614 | CL 614, a derivative of cAIMP, is a novel STING (stimulator of interferon genes)-activating synthetic CDN. Synonyms: cAIMP Difluor; CL614; CL-614; 3'-Adenylic acid, 2'-deoxy-2'-fluoroinosinylyl-(3'→5')-2'-deoxy-2'-fluoro-, cyclic nucleotide; c-(2'FdAMP-2'FdIMP) sodium salt; 9-((2R,3R,3aR,7aR,9R,10R,10aR,14aR)-9-(6-amino-9H-purin-9-yl)-3,10-difluoro-5,12-dihydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9]tetraoxa[2,8]diphosphacyclododecin-2-yl)-1,9-dihydro-6H-purin-6-one. CAS No. 1951464-78-0. Molecular formula: C20H21F2N9O11P2. Mole weight: 663.38. | |
| CL656 | CL656 is an agonist of stimulator of interferon genes (STING) for treating cancer. Synonyms: c-[2'FdAMP(S)-2'FdIMP(S)]; cAIM(PS)2 Difluor (Rp/Sp); Adenosine, 2'-deoxy-2'-fluoro-5'-O-(hydroxymercaptophosphinyl)-P-thioinosinylyl-(3'→5')-2'-deoxy-2'-fluoro-, cyclic nucleotide; CL 656; CL-656; (Rp/Sp) c-[2'FdAM(PS)-2'FdIM(PS]); 9-((2R,3R,3aR,7aR,9R,10R,10aR,14aR)-9-(6-amino-9H-purin-9-yl)-3,10-difluoro-12-hydroxy-5-mercapto-5-oxido-12-sulfidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9]tetraoxa[2,8]diphosphacyclododecin-2-yl)-1,9-dihydro-6H-purin-6-one. Grade: >98%. CAS No. 1951464-79-1. Molecular formula: C20H21F2N9O9P2S2. Mole weight: 695.51. | |
| CL 82,198 | CL 82,198 is a selective inhibitor of human collagenase-3, also known as matrix metalloproteinase-13 (MMP-13). It doesn't have effect against MMP-1, MMP-9 or TNF-α converting enzyme. CL 82,198 is also used to evaluate the role of MMP-13 in diverse processes, including cancer cell migration, acute lung injury, and joint degeneration associated with osteoarthritis. Synonyms: CL-82198; N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide. Grade: ≥95%. CAS No. 307002-71-7. Molecular formula: C17H22N2O3. Mole weight: 302.4. | |
| CL 82198 hydrochloride | The hydrochloride salt form of CL 82198, an inhibitor of MMP-13, has been found to restrain in vitro invasion by the human pituitary adenoma cell line HP75. Synonyms: CL 82198 hydrochloride; CL82198 hydrochloride; CL-82198 hydrochloride; N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide hydrochloride. Grade: ≥98% by HPLC. CAS No. 1188890-36-9. Molecular formula: C17H23N2O3.HCl. Mole weight: 338.83. | |
| Cladinose | Cladinose, an imperative chemical modification present in the macrolide category of antibacterial medications, demonstrates its excellence in combating Gram-positive bacteria, even the drug-resistant variants. With its pivotal role, Cladinose actively treats bacterial infections involving pneumonia, respiratory tract infections, skin and soft tissue infections, as well as selective sexually transmitted diseases. Notably, the inclusion of Cladinose remarkably enhances the efficiency and potency of these antibiotics, thereby advancing their therapeutic outcomes. Synonyms: L-Cladinose; 2,6-Dideoxy-3-C-methyl-3-O-methyl-ribo-hexose; Azithromycin Impurity 4; (4R,5S,6S)-4-Methoxy-4,6-dimethyltetrahydro-2H-pyran-2,5-diol; 3-C,3-O-Dimethyl-2,6-dideoxy-D-ribo-hexose. Grade: ≥95%. CAS No. 470-12-2. Molecular formula: C8H16O4. Mole weight: 176.21. | |
| Cladribine | 2-Chloro-2'-deoxyadenosine is an analog of adenosine that is resistant to both proliferating and non-dividing lymphocytes (IC50 = 45 nM). When phosphorylated, 2-Chloro-2'-deoxyadenosine accumulates in cells and inhibits ribonucleotide reductase. Synonyms: 2-Chloro-2'-deoxyadenosine; Leustatine; 2-CdA; 9-(2'-Deoxy-β-D-ribofuranosyl)-2-chloro-adenine; 2-Chlorodeoxyadenosine; (2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 2-chloro-6-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl)purine. Grade: ≥95%. CAS No. 4291-63-8. Molecular formula: C10H12ClN5O3. Mole weight: 285.69. | |
| Cladribine 5'-Monophosphate Ammonium Salt | Cladribine 5'-Monophosphate Ammonium Salt can be used as an antiviral, antibacterial and antileukemic agent. Grade: 97%. Molecular formula: C10H16ClN6O6P. Mole weight: 382.7. | |
| Cladribine Impurity D | 1'-epi-Cladribine is an impurity of Cladribine, a substituted purine nucleoside with antileukemic activity. Synonyms: 1'-epi-Cladribine; 2-Chloro-9-(2-deoxy-α-D-erythro-pentofuranosyl)-adenine; 2-Chloro-6-amino-9-(2-deoxy-α-D-erythro-pentofuranosyl)purine; 2-Chloro-α-D-2'-deoxyadenosine; NSC 105013. Grade: > 95%. CAS No. 5542-92-7. Molecular formula: C10H12ClN5O3. Mole weight: 285.69. | |
| Cladribine Impurity F | Cladribine Impurity F is an impurity of cladribine, a medication utilized for the therapy of hairy cell leukemia and multiple sclerosis. Synonyms: 4-Methylbenzamide; p-Toluamide. Grade: > 95%. CAS No. 619-55-6. Molecular formula: C8H9NO. Mole weight: 135.16. | |
| Cladribine Impurity G | Methyl p-toluate is an impurity of 3-Toluoyl Decitabine, which is an intermediate of decitabine. It is used as cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines. Synonyms: Methyl p-Toluate; 4-(Methoxycarbonyl)toluene; 4-Methylbenzoic Acid Methyl Ester; Methyl 4-Methylbenzoate; Methyl 4-Toluate; Methyl p-Methylbenzoate; Methyl p-Toluate; Methyl p-Toluenecarboxylate; NSC 24761; p-(Methoxycarbonyl)toluene; p- Carbomethoxytolue. Grade: > 95%. CAS No. 99-75-2. Molecular formula: C9H10O2. Mole weight: 150.17. | |
| Cladribine Related Compound A | 2-Methoxy-2'-deoxyadenosine is an impurity in the synthesis of Cladribine, a substituted purine nucleoside with antileukemic activity. Synonyms: 2-Methoxy-2'-deoxyadenosine; 2-Methoxy-6-amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)purine; 9-(2-Deoxy-β-D-ribofuranosyl)-2-methoxyadenine; 2'-Deoxy-2-methoxyadenosine; (2R,3S,5R)-5-(6-Amino-2-methoxy-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 2'-Deoxyspongosine. Grade: ≥95%. CAS No. 24757-70-8. Molecular formula: C11H15N5O4. Mole weight: 281.27. | |
| Claficapavir | Claficapavir, a specific nucleocapsid protein (NC) inhibitor with an IC50 of about 1 μM, strongly binds to HIV-1 NC (Kd = 20 nM) thereby inhibiting the chaperone properties of NC and resulting in good antiviral activity against HIV-1. Synonyms: A1752; 3-Thiazolidinepropanoic acid, 5-[[5-(4-chlorophenyl)-2-furanyl]methylene]-4-oxo-2-thioxo-, (5Z)-; (Z)-3-(5-((5-(4-chlorophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid. Grade: >98% (HPLC). CAS No. 2055732-24-4. Molecular formula: C17H12ClNO4S2. Mole weight: 393.86. | |
| Cl-amidine | Cl-amidine is an inhibitor of irreversible protein pan-peptidylarginine deiminase (PAD) with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. It irreversibly inactivates all four PAD subtypes by covalently modifying an active site cysteine that is important for its catalytic activity. Synonyms: N-[(1S)-1-(aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamide. Grade: ≥95%. CAS No. 1043444-18-3. Molecular formula: C14H19ClN4O2·C2HF3O2. Mole weight: 424.8. | |
| Cl-Amidine hydrochloride | Cl-amidine is an inhibitor of irreversible protein pan-peptidylarginine deiminase (PAD) with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. It irreversibly inactivates all four PAD subtypes by covalently modifying an active site cysteine that is important for its catalytic activity. Synonyms: N-[(1S)-1-(aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamide monohydrochloride. Grade: ≥95%. CAS No. 1373232-26-8. Molecular formula: C14H19ClN4O2·HCl. Mole weight: 347.24. | |
| Clamoxyquin Hydrochloride | Clamoxyquine, as the pamoate or hydrochloride salt, is an antiamebic and antidiarrheal drug used as a veterinary medicine to treat salmonids for infection with the myxozoan parasite Myxobolus cerebralis. Uses: Antiamebic and antidiarrheal. Synonyms: 5-chloro-7-[[3-(diethylamino)propylamino]methyl]quinolin-8-ol; dihydrochloride. Grade: ≥98%. CAS No. 4724-59-8. Molecular formula: C17H26Cl3N3O. Mole weight: 394.76. | |
| Clanfenur | Clanfenur belongs to a new group of substituted benzoylphenylureas. It is a potent cytotoxic agent with potential anti-neoplastic activity. Synonyms: 1-(p-Chlorophenyl)-3-(6-fluoro-N,N-dimethylanthraniloyl)urea. Grade: 95%. CAS No. 51213-99-1. Molecular formula: C16H15ClFN3O2. Mole weight: 335.76. | |
| Cl-ANT-ATP | Cl-ANT-ATP is an analogue of adenosine-5'-triphosphate, of which the intrinsic fluorescence would increase in hydrophobic environment. It can be used to study ATP-dependent receptor proteins. Synonyms: 2'- / 3'- O- (5- Chloroanthraniloyl)adenosine- 5'- O- triphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 1350521-45-7. Molecular formula: C17H20ClN6O14P3 (free acid). Mole weight: 660.8 (free acid). | |
| Cl-ANT-ITP | Cl-ANT-ITP is an analogue of inosine-5'-triphosphate and an inhibitor of mammalian adenylate cyclases, of which the intrinsic fluorescence would increase in hydrophobic environment. Synonyms: 2'- / 3'- O- (5- Chloroanthraniloyl)inosine- 5'- O- triphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 1350521-48-0. Molecular formula: C17H19ClN5O15P3 (free acid). Mole weight: 661.7 (free acid). | |
| Clarithromycin 2'-O-Acetate | Clarithromycin 2'-O-Acetate is an intermediate in synthesizing 4'',6-Di-O-methylerythromycin, which is a derivative of O-Methylerythromycin and may be used in the treatment of lung diseases requiring antibiotics. Synonyms: 2'-O-Acetylclarithromycin; 2'-O-Acetyl-6-O-methylerythromycin A; Oxacyclotetradecane Erythromycin Derivative; 6-O-Methyl-erythromycin 2'-Acetate; (2S,3R,4S,6R)-4-(Dimethylamino)-2-(((3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl)oxy)-6-methyltetrahydro-2H-pyran-3-yl Acetate. CAS No. 103461-66-1. Molecular formula: C40H71NO14. Mole weight: 789.99. | |
| Clarithromycin 2'-O-Acetate N-Methyl Iodide | Clarithromycin 2'-O-Acetate N-Methyl Iodide is an intermediate in synthesizing 4'',6-Di-O-methylerythromycin, which is a derivative of O-Methylerythromycin and may be used in the treatment of lung diseases requiring antibiotics. Molecular formula: C41H74INO14. Mole weight: 931.93. | |
| Clarithromycin (9E)-O-Methyloxime | Clarithromycin (9E)-O-Methyloxime (Clarithromycin EP Impurity G) is an impurity of Clarithromycin, a macrolide antibiotic. Clarithromycin impurity G. Synonyms: 6-O-Methylerythromycin (9E)-9-(O-Methyloxime); Clarithromycin Impurity G; Clarithromycin EP Impurity G; (9E)-6-O-Methylerythromycin 9-(O-methyloxime); Erythromycin, 6-O-methyl-, 9-(O-methyloxime), (9E)-. Grade: 98%. CAS No. 127182-44-9. Molecular formula: C39H72N2O13. Mole weight: 776.99. | |
| Clarithromycin EP Impurity A | Clarithromycin EP Impurity A is an impurity of the semi-synthetic macrolide antibiotic Clarithromycin. Synonyms: Clarithromycin F; 16-Hydroxyclarithromycin; 2-Demethyl-2-(hydroxymethyl)-6-O-methylerythromycin A. Grade: ≥95%. CAS No. 124412-58-4. Molecular formula: C38H69NO14. Mole weight: 763.96. | |
| Clarithromycin EP Impurity P | 4'',6-Di-O-methylerythromycin is a derivative of O-methylerythromycin and may be used in the treatment of lung diseases requiring antibiotics. Synonyms: 4'',6-Di-O-methylerythromycin; Oxacyclotetradecane, Erythromycin deriv.; 4'-O-Methylclarithromycin. Grade: > 95%. CAS No. 123967-58-8. Molecular formula: C39H71NO13. Mole weight: 761.98. | |
| Clarithromycin Hydrazone | Clarithromycin Hydrazone is an intermediate in the synthesis of 12-O-Methyl Clarithromycin which is a methylated impurity of the semi-synthetic macrolide antibiotic Clarithromycin. 12-O-Methyl Clarithromycin was shown to inhibit uptake of Clarithromycin into the lung cells. Synonyms: 6-O-Methylerythromycin Hydrazone; 6-O-Methyl-erythromycin 9-Hydrazone; (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-10-hydrazineylidene-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one; Erythromycin, 6-O-methyl-, 9-hydrazone. CAS No. 220745-18-6. Molecular formula: C38H71N3O12. Mole weight: 761.98. | |
| Clarithromycin Impurity C | Clarithromycin Impurity C is an impurity of Clarithromycin, an antibiotic used to treat a variety of bacterial infections. Synonyms: Clarithromycin oxime. Grade: > 95%. CAS No. 127253-06-9. Molecular formula: C38H70N2O13. Mole weight: 762.97. | |
| Clarithromycin Impurity E | An impurity of Clarithromycin. 11-O-Methylclarithromycin is a semisynthetic derivative of the macrolide antibiotic erythromycin. It is characterized by the presence of a methyl group at the 11-position of the clarithromycin molecule, which modifies its pharmacological properties. This compound exhibits broad-spectrum antibacterial activity and is particularly effective against certain Gram-positive bacteria. Synonyms: 6,11-Di-O-methylerythromycin; 11-O-Methylclarithromycin; USP Clarithromycin Related Compound A. Grade: >95%. CAS No. 81103-14-2. Molecular formula: C39H71NO13. Mole weight: 761.98. | |
| Clarithromycin Impurity G (Mixture of Z and E Isomers) | Clarithromycin Impurity G (Mixture of Z and E Isomers) is a an impurity of Clarithromycin, an antibiotic widely employed in treating various bacterial infections, including respiratory tract infections, skin and soft tissue infections and Helicobacter pylori infections associated with peptic ulcers. Grade: > 95%. CAS No. 107216-09-1. Molecular formula: C39H72N2O13. Mole weight: 777.01. | |
| Clarithromycin Impurity L | Clarithromycin (9Z)-Oxime is an impurity of Clarithromycin. Synonyms: Clarithromycin (9Z)-Oxime; 6-O-Methylerythromycin (9Z)-9-Oxime; (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,Z)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-di. Grade: >95%. CAS No. 127253-05-8. Molecular formula: C38H70N2O13. Mole weight: 762.97. | |
| Clarithromycin Impurity N | (10E)-10,11-Didehydro-11-deoxy-6-O-methylerythromycin is the Erythromycin derivative. Synonyms: (10E)-10,11-Didehydro-11-deoxy-6-O-methylerythromycin; Oxacyclotetradecane Erythromycin Derivative. Grade: > 95%. CAS No. 144604-03-5. Molecular formula: C38H67NO12. Mole weight: 729.94. | |
| Clarithromycin Impurity O | Clarithromycin (9Z)-O-Methyloxime is an impurity of Clarithromycin. Synonyms: Clarithromycin (9Z)-O-Methyloxime; 6-O-Methylerythromycin (9Z)-9-O-Methyloxime; Oxacyclotetradecane Erythromycin deriv.; Erythromycin, 6-O-methyl-, 9-O-methyloxime, (9Z)-; (9Z)-6-O-Methylerythromycin 9-(O-methyloxime). Grade: >95%. CAS No. 127252-80-6. Molecular formula: C39H72N2O13. Mole weight: 776.99. | |
| Clarithromycin lactobionate | Clarithromycin, a CYP3A4 inhibitor, is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia, skin and skin structure infections. Synonyms: Erythromycin, 6-O-methyl-, 4-O-β-D-galactopyranosyl-D-gluconate (salt); D-Gluconic acid, 4-O-β-D-galactopyranosyl-, compd with 6-O-methylerythromycin (1:1); (2R,3R,4R,5R)-2,3,5,6-Tetrahydroxy-4-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}hexanoic acid with (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (1:1). Grade: ≥95%. CAS No. 135326-55-5. Molecular formula: C38H69NO13.C12H22O12. Mole weight: 1106.25. | |
| Clarithromycin N-Oxide | Clarithromycin N-oxide is an urinary metabolite of Clarithromycin, a macrolide antibiotic. Synonyms: 6-O-Methylerythromycin N-Oxide; USP Clarithromycin Impurity Q. Grade: > 95%. CAS No. 118074-07-0. Molecular formula: C38H69NO14. Mole weight: 763.95. | |
| Clarithromycin related compound H | N-Demethyl-N-formylclarithromycin is an impurity of the semi-synthetic macrolide antibiotic Clarithromycin. Synonyms: N-Demethyl-N-formyl Clarithromycin; N-Demethyl-N-formyl-6-O-methylerythromycin; 3"-N-Demethyl-3"-N-formylclarithromycin; USP Clarithromycin Impurity H; Clarithromycin impurity H. Grade: >95%. CAS No. 127140-69-6. Molecular formula: C38H67NO14. Mole weight: 761.94. | |
| Clarithromycin related compound K | 3-O-De(cladinosyl)-8,9,10,11-tetradehydro-9-deoxo-11,12-dideoxy-9,12-epoxy Clarithromycin is an impurity of Clarithromycin. Synonyms: 3-O-De(cladinosyl)-8,9,10,11-tetradehydro-9-deoxo-11,12-dideoxy-9,12-epoxy Clarithromycin; 3-O-De(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)-8,9,10,11-tetradehydro-9-deoxo-11,12-dideoxy-9,12-epoxy-6-O-methylerythromycin; Clarithromycin EP Impurity K. Grade: >95%. CAS No. 127157-35-1. Molecular formula: C30H51NO8. Mole weight: 553.73. | |
| Clarithromycin related compound M | N-Desmethyl-6-O-methylerythromycin (9E)-Oxime is a derivative of Clarithromycin. Synonyms: N-Desmethyl-6-O-methylerythromycin (9E)-Oxime; 3''-N-Demethyl-6-O-methylerythromycin A (E)-9-oxime. Grade: >95%. CAS No. 127182-43-8. Molecular formula: C37H68N2O13. Mole weight: 748.94. | |
| Clarithromycin Trimethylsilyl O-Methyl Trityl Hydrazone | Clarithromycin Trimethylsilyl O-Methyl Trityl Hydrazone is an intermediate in synthesizing 4'',6-Di-O-methylerythromycin, a derivative of O-methylerythromycin and may be used in the treatment of lung diseases requiring antibiotics. Synonyms: (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-4-(((2R,4R,5S,6S)-4,5-Dimethoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-7-methoxy-3,5,7,9,11,13-hexamethyl-10-(2-tritylhydrazono)oxacyclotetradecan-2-one. Molecular formula: C61H95N3O12Si. Mole weight: 1090.51. | |
| Clarithromycin Trimethylsilyl Trityl Hydrazone | Clarithromycin Trimethylsilyl Trityl Hydrazone is an intermediate in synthesizing 4'',6-Di-O-methylerythromycin, a derivative of O-methylerythromycin and may be used in the treatment of lung diseases requiring antibiotics. Synonyms: (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3,5,7,9,11,13-hexamethyl-10-(2-tritylhydrazono)oxacyclotetradecan-2-one. Molecular formula: C60H93N3O12Si. Mole weight: 1076.48. | |
| Clarithromycin Trityl Hydrazone | Clarithromycin Trityl Hydrazone is an intermediate in synthesizing 4'',6-Di-O-methylerythromycin, a derivative of O-methylerythromycin and may be used in the treatment of lung diseases requiring antibiotics. Synonyms: (9E)-6-O-Methylerythromycin 9-[2-(triphenylmethyl)hydrazone]; Erythromycin, 6-O-methyl-, 9-[2-(triphenylmethyl)hydrazone], (9E)-; (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3,5,7,9,11,13-hexamethyl-10-(2-tritylhydrazono)oxacyclotetradecan-2-one. CAS No. 1030374-65-2. Molecular formula: C57H85N3O12. Mole weight: 1004.30. | |
| Clavam-2-carboxylate Potassium | Clavam-2-carboxylate Potassium is an impurity of Clavulanic Acid, a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness. Synonyms: (3R,5S)-7-oxo-1-azabicyclo[3.2.0]heptane-3-carboxylate Potassium. CAS No. 2196185-67-6. Molecular formula: C6H6KNO4. Mole weight: 195.21. | |
| Clazakizumab | Clazakizumab is a monoclonal antibody directed against interleukin-6. Clazakizumab has been undergoing a clinical trial for the treatment of CABMR in recipients of a kidney transplant. Synonyms: ALD518; BMS-945429. CAS No. 1236278-28-6. | |
| Clazosentan | Clazosentan, also called as AXV 034, Ro 61-1790 or VML 588, a novel endothelin A antagonist, improves cerebral blood flow and behavior after traumatic brain injury. In 2016 Actelion plans two phase III trials of Clazosentan for Cerebral vasospasm (in patients with aneurysmal subarachnoid haemorrhage) in Japan. Synonyms: N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl]-5-methylpyridine-2-sulfonamideAXV034; AXV-034; AXV 034; AXV 034343; AXV-034343; AXV-343434; Ro 61-1790; Ro-61-1790; VML 588; VML-588; VML 588; Clazosentan. Grade: 95%. CAS No. 180384-56-9. Molecular formula: C25H23N9O6S. Mole weight: 577.57. | |
| Clazuril | Clazuril is a synthetic coccidiostat drug administered to animals especially in poultry, to cure coccidiosis. Clazuril has a coccidiocidal effect on the asexual and sexual developmental stages of both Eimeria species, resulting in a complete interruption of the life cycle. Synonyms: R-62690; R62,690; Clazurilum; Clazurilo; (2-Chloro-4-(4,5-dihydro-3,5-dioxo-as-triazin-2(3H)-yl)phenyl)(p-chlorophenyl)acetonitrile. Grade: 95%. CAS No. 101831-36-1. Molecular formula: C17H10Cl2N4O2. Mole weight: 373.19. | |
| Clebopride Malate | Clebopride is a substituted benzamide as a dopamine antagonist used to treat functional gastrointestinal disorders. Uses: Dopamine antagonist. Synonyms: 4-Amino-5-chloro-2-methoxy-N-(1-benzyl-4-piperidyl)benzamide malate; 4-amino-N-(1-benzylpiperidin-1-ium-4-yl)-5-chloro-2-methoxybenzamide; 2,4-dihydroxy-4-oxobutanoate. Grade: ≥95%. CAS No. 57645-91-7. Molecular formula: C23H28ClN3O6. Mole weight: 477.94. | |
| CLEFMA | CLEFMA is a curcumin analog that elevates ROS levels and induces oxidative stress and apoptosis in lung cancer cell lines. CLEFMA inhibits tumor growth in lung cance xenografts. Synonyms: 4-[3,5-Bis[(2-chlorophenyl)methylene]-4-oxo-1-piperidinyl]-4-oxo-2-butenoic acid. CAS No. 1246964-32-8. Molecular formula: C23H17Cl2NO4. Mole weight: 442.29. | |
| Cleistanthin B | Cleistanthin B has a role as an antihypertensive agent. It is a member of cleistanthins, Cleistanthin B exhibits anti-SARS-CoV-2 effects in Vero cells. Synonyms: Diphyllin O-glucoside; Clei B. Grade: 98%. CAS No. 30021-77-3. Molecular formula: C27H26O12. Mole weight: 542.49. | |
| Clemastine | Clemastine is a histamine H1 antagonist commonly used for the symptoms of allergic rhinitis, hay fever, and cold. Uses: Anti-allergic agents. Synonyms: HS 592; HS-592; HS592; Meclastin; Mecloprodin; Clemastina; Tavist; Meclastine. CAS No. 15686-51-8. Molecular formula: C21H26ClNO. Mole weight: 343.895. | |
| Clemastine Fumarate Impurity B | N-Methyl-4-[1-(4-chlorophenyl)-1-phenylethoxy)hexahydroazepine is an impurity in the synthesis of Clemastine Fumarate, a H1 histamine receptor antagonist and antihistaminic. Synonyms: N-Methyl-4-[1-(4-chlorophenyl)-1-phenylethoxy)hexahydroazepine; 4-(1-(4-Chlorophenyl)-1-phenylethoxy)-1-methylazepane; 4-[1-(4-Chlorophenyl)-1-phenylethoxy]hexahydro-1-methyl-1H-azepine. Grade: > 95%. CAS No. 61771-18-4. Molecular formula: C21H26ClNO. Mole weight: 343.89. | |
| Clemastine Fumarate Impurity C | 1-(4-Chlorophenyl)-1-phenylethanol is used in the synthetic preparation of rhodium-catalyzed arylation of nitriles, ketones and imines with tetrafluoroborate or arylboronic acids. Synonyms: 1-(4-Chlorophenyl)-1-phenylethanol; 4-Chloro-α-methyl-benzhydrol; p-Chlorophenyl)methylphenylcarbinol; 1-(4-Chlorophenyl)-1-phenylethanol; 1-(p-Chlorophenyl)-1-phenylethanol; 4-Chloro(α-methyl-α-phenyl)benzenemethanol; EGIS 5927; p-Chloro-α-methylbenzhydr. Grade: > 95%. CAS No. 59767-24-7. Molecular formula: C14H13ClO. Mole weight: 232.71. | |
| Clemastine N-Oxide | Clemastine N-Oxide is a metabolite of Clemastine Fumarate, a H1 histamine receptor antagonist and antihistaminic. Synonyms: [R-(R*,R*)]- 2-[2-[1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine 1-Oxide. Grade: > 95%. CAS No. 108825-05-4. Molecular formula: C21H26ClNO2. Mole weight: 359.89. | |
| Clemizole | Clemizole is an H1 antagonist acts as a TRPC5 channel blocker (IC50 values are 1.1, 6.4, 9.1, 11.3 and 26.5 μM for TRPC5, TRPC4, TRPC3, TRPC6 and TRPC7 respectively). Uses: Trpc5 channel blocker. Synonyms: Clemizole; 442-52-4; Histacur; Clemizol; Histakool; 1-(4-Chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzo[d]imidazole; Clemizolum; Lergopenin; Depocural; 1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole; 1-(p-Chlorobenzyl)-2-pyrrolidylmethylenebenzimidazole; 1-p-Chlorobenzyl-2-(1-pyrrolidinylmethyl)benzimidazole; NSC 46261; NSC-46261; AL-20 FREE BASE; CHEBI:52140; T97CB3796L; AL 2. Grade: ≥95%. CAS No. 442-52-4. Molecular formula: C19H20ClN3. Mole weight: 325.84. | |
| Clemizole hydrochloride | The hydrochloride salt form of clemizole, which is a histamine H1 antagonist with antitumor activity. It also has hepatitis C antiviral effect through restraining NS4B function and could also be used as an anticonvulsant in zebrafish Dravet syndrome model. Synonyms: Allercur; Clemizole HCl; Clemizole (hydrochloride); Reactrol; 1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole hydrochloride. Grade: 95%. CAS No. 1163-36-6. Molecular formula: C19H20ClN3.HCl. Mole weight: 362.30. | |
| Clenbuterol-D6 HCl | Clenbuterol-D6 HCl is a labelled salt of Clenbuterol. Clenbuterol is a β2 agonist used as a bronchodilator for the treatment of breathing disorders including asthma. Synonyms: 1-(4-Amino-3,5-dichlorophenyl)-2-tert-butyl-D6-aminoethanol hydrochloride. Grade: 95% by HPLC; 98% atom D. Molecular formula: C12H13D6Cl3N2O. Mole weight: 319.691. | |
| Clenbuterol-d9 | Clenbuterol-d9 is a β-Agonist which can be used as a growth promoter in farm animals. Synonyms: 4-Amino-3,5-dichloro-α-[[(1,1-dimethylethyl-d9)amino]methyl]benzenemethanol; 4-amino-3,5-dichloro-α-[[[1,1-di(methyl-d3)ethyl-2,2,2-d3]amino]methyl]benzenemethanol. Grade: > 95%. CAS No. 129138-58-5. Molecular formula: C12H9Cl2N2OD9. Mole weight: 286.25. | |
| Clenbuterol-D9 hydrochloride | Clenbuterol-D9 hydrochloride is a labelled salt of Clenbuterol. Clenbuterol is a β2 agonist used as a bronchodilator for the treatment of breathing disorders including asthma. Synonyms: 1-(4-Amino-3.5-dichlorophenyl)-2-tert-butyl-D9-aminoethanol hydrochloride. Grade: 95% by HPLC; 98% atom D. CAS No. 184006-60-8. Molecular formula: C12H19Cl3N2O. Mole weight: 322.71. | |
Our database is helping our users find suppliers everyday.
