Creative Enzymes - Products
Enzyme manufacturing for life science research and medicines, food, alcohol, fabric, paper etc. Uses include: drug discovery, cancer and infectious disease research, microbiology and personalized medicine.
| Product | Description | |
|---|---|---|
| cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming] | This enzyme, found in several bacterial pathogens, is involved in degradation of the host's cholesterol. It catalyses the hydroxylation of the C-26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate, initiating the degradation of the alkyl side-chain of cholesterol. The products are exclusively in the (25S) configuration. It is a two-component system consisting of a P-450 (heme thiolate) oxygenase (Cyp125) and a ferredoxin reductase (most likely KshB, which is also a part of EC 1.14.13.142, 3-ketosteroid 9α-monooxygenase). The enzyme also accepts cholesterol as a substrate. cf. EC 1.14.13.221, cholest-4-en-3-one 27-monooxygenase. Group: Enzymes. Synonyms: CYP125; CYP125A1; cholest-4-en-3-one 27-monooxygenase (misleading); cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxyl. Enzyme Commission Number: EC 1.14.13.141. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0741; cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]; EC 1.14.13.141; CYP125; CYP125A1; cholest-4-en-3-one 27-monooxygenase (misleading); cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxylating); cholest-4-en-3-one 26-monooxygenase (ambiguous). Cat No: EXWM-0741. |  |
| cholest-5-ene-3β,7α-diol 3β-dehydrogenase | Highly specific for 3β-hydroxy-C27-steroids with Δ5-double bond. Group: Enzymes. Synonyms: 3β-hydroxy-Δ5-C27-steroid oxidoreductase. Enzyme Commission Number: EC 1.1.1.181. CAS No. 56626-16-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0084; cholest-5-ene-3β,7α-diol 3β-dehydrogenase; EC 1.1.1.181; 56626-16-5; 3β-hydroxy-Δ5-C27-steroid oxidoreductase. Cat No: EXWM-0084. | |
| cholestanetriol 26-monooxygenase | This mitochondrial cytochrome P-450 enzyme requires adrenodoxin. It catalyses the first three sterol side chain oxidations in bile acid biosynthesis via the neutral (classic) pathway. Can also act on cholesterol, cholest-5-ene-3β,7α-diol, 7α-hydroxycholest-4-en-3-one, and 5β-cholestane-3α,7α-diol. The enzyme can also hydroxylate cholesterol at positions 24 and 25. The initial source of the electrons is NADPH, which transfers the electrons to the adrenodoxin via EC 1.18.1.6, adrenodoxin-NADP+ reductase. Group: Enzymes. Synonyms: 5β-cholestane-3α,7α,12α-triol 26-hydroxylase; 5β-cholestane-3α,7α,12α-triol hydroxylase; cholestanetriol 26-hydroxylase; sterol 27-hydroxylase; sterol 26-hydroxylase; cholesterol 27-hydroxyla. Enzyme Commission Number: EC 1.14.15.15. CAS No. 52227-77-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0940; cholestanetriol 26-monooxygenase; EC 1.14.15.15; 52227-77-7; 5β-cholestane-3α,7α,12α-triol 26-hydroxylase; 5β-cholestane-3α,7α,12α-triol hydroxylase; cholestanetriol 26-hydroxylase; sterol 27-hydroxylase; sterol 26-hydroxylase; cholesterol 27-hydroxylase; CYP27A; CYP27A1; cytochrome P450 27A1'. Cat No: EXWM-0940. | |
| cholestanol-d5 | cholestanol-d5. Group: Others. Purity: >99%. Mole weight: 393.7. Stability: 6 Months. Storage: -20°C. Avanti Polar Lipids; lipid products; sterols; sterols products; singnal transduction; cell pathways; cholestanol-d5; 2,2,3,4,4-pentadeuterio-5a-cholestan-3ss-ol. Cat No: STEZ-073. | |
| cholestenoic acid-d5 | cholestenoic acid-d5. Group: Others. Purity: >99%. Mole weight: 421.667. Stability: 6 Months. Storage: -20°C. Avanti Polar Lipids; lipid products; sterols; sterols products; singnal transduction; cell pathways; cholestenoic acid-d5; 3ss-hydroxy-5-cholestenoic acid-d5. Cat No: STEZ-036. | |
| cholestenol Δ-isomerase | This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. This enzyme participates in biosynthesis of steroids. Group: Enzymes. Enzyme Commission Number: EC 5.3.3.5. CAS No. 52410-46-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5502; cholestenol Δ-isomerase; EC 5.3.3.5; 52410-46-5. Cat No: EXWM-5502. | |
| cholesterol 24-hydroxylase | A P-450 heme-thiolate protein. The enzyme can also produce 25-hydroxycholesterol. In addition, it can further hydroxylate the product to 24,25-dihydroxycholesterol and 24,27-dihydroxycholesterol. This reaction is the first step in the enzymic degradation of cholesterol in the brain as hydroxycholesterol can pass the blood-brain barrier whereas cholesterol cannot. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: cholesterol 24-monooxygenase; CYP46; CYP46A1; cholesterol 24S-hydroxylase; cytochrome P450 46A1. Enzyme Commission Number: EC 1.14.14.25. CAS No. 50812-30-1, 213327-78-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0922; cholesterol 24-hydroxylase; EC 1.14.14.25; 50812-30-1, 213327-78-7; cholesterol 24-monooxygenase; CYP46; CYP46A1; cholesterol 24S-hydroxylase; cytochrome P450 46A1. Cat No: EXWM-0922. | |
| cholesterol 25-hydroxylase | Unlike most other sterol hydroxylases, this enzyme is not a cytochrome P-450. Instead, it uses diiron cofactors to catalyse the hydroxylation of hydrophobic substrates. The diiron cofactor can be either Fe-O-Fe or Fe-OH-Fe and is bound to the enzyme through interactions with clustered histidine or glutamate residues. In cell cultures, this enzyme down-regulates cholesterol synthesis and the processing of sterol regulatory element binding proteins (SREBPs). Group: Enzymes. Synonyms: cholesterol 25-monooxygenase. Enzyme Commission Number: EC 1.14.99.38. CAS No. 60202-07-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1049; cholesterol 25-hydroxylase; EC 1.14.99.38; 60202-07-5; cholesterol 25-monooxygenase. Cat No: EXWM-1049. | |
| cholesterol-5,6-oxide hydrolase | The enzyme appears to work equally well with either epoxide as substrate. The product is a competitive inhibitor of the reaction. In vertebrates, five epoxide-hydrolase enzymes have been identified to date: EC 3.3.2.6 (leukotriene-A4 hydrolase), EC 3.3.2.7 (hepoxilin-epoxide hydrolase), EC 3.3.2.9 (microsomal epoxide hydrolase), EC 3.3.2.10 (soluble epoxide hydrolase) and EC 3.3.2.11 (cholesterol 5,6-oxide hydrolase). Group: Enzymes. Synonyms: cholesterol-epoxide hydrolase; ChEH. Enzyme Commission Number: EC 3.3.2.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3996; cholesterol-5,6-oxide hydrolase; EC 3.3.2.11; cholesterol-epoxide hydrolase; ChEH. Cat No: EXWM-3996. | |
| cholesterol 7α-monooxygenase | A P-450 heme-thiolate liver protein that catalyses the first step in the biosynthesis of bile acids. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: cholesterol 7α-hydroxylase; CYP7A1 (gene name). Enzyme Commission Number: EC 1.14.14.23. CAS No. 9037-53-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0920; cholesterol 7α-monooxygenase; EC 1.14.14.23; 9037-53-0; cholesterol 7α-hydroxylase; CYP7A1 (gene name). Cat No: EXWM-0920. | |
| cholesterol 7-desaturase | The enzyme, characterized from several organisms including the worm Caenorhabditis elegans, the fly Drosophila melanogaster, and the ciliate Tetrahymena thermophila, is a Rieske oxygenase. In insects it participates in the the biosythesis of ecdysteroid hormones. The electrons are transferred from NAD(P)H via an electron transfer chain likely to include ferredoxin reductase and ferredoxin. The enzyme differs from regular desaturases, such as EC 1.14.19.20, 7-sterol 5(6)-desaturase, which are cytochrome b5-dependent and contain the three His-boxes that are typical to most desaturases. Group: Enzymes. Synonyms: nvd (gene name); daf-36 (gene name). Enzyme Commission Number: EC 1.14.19.21. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0984; cholesterol 7-desaturase; EC 1.14.19.21; nvd (gene name); daf-36 (gene name). Cat No: EXWM-0984. | |
| Cholesterol Dehydrogenase from Nocardia sp. | Cholesterol dehydrogenase is an enzyme that uses nicotinamide adenine dinucleotide/nicotinamide adenine dinucleotide phosphate (NAD(P)) as its cofactor in oxidizing cholesterol to form cholest-4-en-3-one. This enzyme oxidizes the hydroxyl group at the 3 position of the sterol ring to form a ketone. Group: Enzymes. Synonyms: Cholesterol Dehydrogenase; CDH. CAS No. 67775-34-2. Activity: 10U/mg-solid or more. Storage: at -20°C. Form: Freeze dried powder. Source: Nocardia sp. Cholesterol Dehydrogenase; CDH. Cat No: NATE-0892. | |
| Cholesterol Esterase from Candida Rugosa | Cholesterol esterase (CE) is also known as cholesterol ester hydrolase. This enzyme catalyzes the following reaction: Sterol Ester --------> Sterol + Fatty Acid. Cholesterol esterase activity has been demonstrated in pancreas, intestine, liver and kidney. The enzyme is inactivated by proteolytic enzymes but stabilized by proteolytic enzyme inhibitors and by bile salts. Group: Enzymes. Synonyms: cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; sterol esterase; CE. Enzyme Commission Number: EC 3.1.1.13. CAS No. 9026-00-0. Purity: 0.9. Activity: 25-100 U/mg. Storage: Store at -20° C. Form: Freeze dried powder. Source: Candida Rugosa. cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; sterol esterase; CE. Cat No: NATE-1679. | |
| Cholesterol Esterase from E. coli, Recombinant | Sterol esterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is steryl-ester acylhydrolase. This enzyme participates in bile acid biosynthesis. Group: Enzymes. Synonyms: cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Enzyme Commission Number: EC 3.1.1.13. CAS No. 9026-00-0. Cholesterol Esterase. Mole weight: ca. 54 kDa. Activity: > 5 U/mg lyophilizate. Appearance: Light yellow lyophilizate. Source: E. coli. Species: E. coli. cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Cat No: DIA-405. | |
| Cholesterol Esterase from Microorganism | Cholesterol esterase (CE) is also known as cholesterol ester hydrolase. This enzyme catalyzes the following reaction: Sterol Ester --------> Sterol + Fatty Acid. Cholesterol esterase activity has been demonstrated in pancreas, intestine, liver and kidney. The enzyme is inactivated by proteolytic enzymes but stabilized by proteolytic enzyme inhibitors and by bile salts. Group: Enzymes. Synonyms: cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Enzyme Commission Number: EC 3.1.1.13. CAS No. 9026-00-0. Activity: 5.0U/mg-solid or more. Form: Freeze dried powder. Source: Microorganism. cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Cat No: DIA-135. | |
| Cholesterol Esterase from Pseudomonas sp. | Cholesterol esterase (CE) is also known as cholesterol ester hydrolase. This enzyme catalyzes the following reaction: Sterol Ester --------> Sterol + Fatty Acid. Cholesterol esterase activity has been demonstrated in pancreas, intestine, liver and kidney. The enzyme is inactivated by proteolytic enzymes but stabilized by proteolytic enzyme inhibitors and by bile salts. Group: Enzymes. Synonyms: cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Enzyme Commission Number: EC 3.1.1.13. CAS No. 9026-00-0. Activity: 100U/mg-solid or more (containing approx. 40% of stabilizers). Form: Freeze dried powder. Source: Pseudomonas sp. cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Cat No: DIA-134. | |
| Cholesterol Esterase from Schizophyllum commune | Cholesterol esterase (CE) is also known as cholesterol ester hydrolase. This enzyme catalyzes the following reaction: Sterol Ester --------> Sterol + Fatty Acid. Cholesterol esterase activity has been demonstrated in pancreas, intestine, liver and kidney. The enzyme is inactivated by proteolytic enzymes but stabilized by proteolytic enzyme inhibitors and by bile salts. Group: Enzymes. Synonyms: cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Enzyme Commission Number: EC 3.1.1.13. CAS No. 9026-00-0. Activity: 2.0 U/mg-solid or more (containing approx. 20% of stabilizers). Form: Freeze dried powder. Source: Schizophyllum commune. cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Cat No: DIA-133. | |
| Cholesterol Esterase, PEG Modified | PEG (Polyethylene glycol) modified cholesterol esterase (PEG Cholesterol Esterase) isone of our premier cholesterol esterase conjugates. Cholesterol esterase is an enzyme that catalyzes the hydrolysis of cholesterol esters into their sterol components and fatty acids. Cholesterol esterase has clinical applications in the determination of serum cholesterol combined with other enzymes. PEG modified cholesterol esterase shows better stability with good reactivity. All our labeled cholesterol esterase products were performed under mild reaction conditions to retain their maximum bioactivity. These conjugates were further purified by chromatography to ensure adequate applications both in-vitro and in-vivo. Conjugate ration: 20~50 peg5000/monomer. solubility: soluble in aqueous buffer. Group: Enzymes. Synonyms: PEG Cholesterol Esterase; Cholesterol Esterase-polyethylene glycol; CE-polyethylene glycol; CE-PEG; PEG-CE; PEG-Cholesterol Esterase. Cholesterol Esterase. Mole weight: ~65 kD for monomer; 400 kD for hexamer. Activity: >300 units/g. Storage: Store at -20°C. Form: Lyophilized powder. Source: Porcine pancreas. Species: Porcine. PEG Cholesterol Esterase; Cholesterol Esterase-polyethylene glycol; CE-polyethylene glycol; CE-PEG; PEG-CE; PEG-Cholesterol Esterase; Cholesterol Esterase, PEG Modified. Cat No: NATE-1587. | |
| cholesterol monooxygenase (side-chain-cleaving) | A heme-thiolate protein (cytochrome P-450). The reaction proceeds in three stages, with two hydroxylations at C-22 and C-20 preceding scission of the side-chain between carbons 20 and 22. The initial source of the electrons is NADPH, which transfers the electrons to the adrenodoxin via EC 1.18.1.6, adrenodoxin-NADP+ reductase. Group: Enzymes. Synonyms: cholesterol desmolase; cytochrome P-450scc; C27-side chain cleavage enzyme; cholesterol 20-22-desmolase; cholesterol C20-22 desmolase; cholesterol side-chain cleavage enzyme; cholesterol side-chain-cleaving enzyme; steroid 20-22 desmolase; steroid 20-22-lyase; CYP11A1 (gene name). Enzyme Commission Number: EC 1.14.15.6. CAS No. 37292-81-2, 440354-98-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0949; cholesterol monooxygenase (side-chain-cleaving); EC 1.14.15.6; 37292-81-2, 440354-98-3; cholesterol desmolase; cytochrome P-450scc; C27-side chain cleavage enzyme; cholesterol 20-22-desmolase; cholesterol C20-22 desmolase; cholesterol side-chain cleavage enzyme; cholesterol side-chain-cleaving enzyme; steroid 20-22 desmolase; steroid 20-22-lyase; CYP11A1 (gene name). Cat No: EXWM-0949. | |
| cholesterol oxidase | Contains FAD. Cholesterol oxidases are secreted bacterial bifunctional enzymes that catalyse the first two steps in the degradation of cholesterol. The enzyme catalyses the oxidation of the 3β-hydroxyl group to a keto group, and the isomerization of the double bond in the oxidized steroid ring system from the Δ5 position to Δ6 position (cf. EC 5.3.3.1, steroid Δ-isomerase). Group: Enzymes. Synonyms: cholesterol- O2 oxidoreductase; 3β-hydroxy steroid oxidoreductase; 3β-hydroxysteroid:oxygen oxidoreductase. Enzyme Commission Number: EC 1.1.3.6. CAS No. 9028-76-6. CHOD. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0424; cholesterol oxidase; EC 1.1.3.6; 9028-76-6; cholesterol- O2 oxidoreductase; 3β-hydroxy steroid oxidoreductase; 3β-hydroxysteroid:oxygen oxidoreductase. Cat No: EXWM-0424. | |
| Cholesterol oxidase from E. coli, Recombinant | Recombinant Cholesterol Oxidase belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. This enzyme participates in bile acid biosynthesis. Group: Enzymes. Synonyms: EC 1.1.3.6, cholesterol-O2 oxidoreductase; 3β-hydroxy steroid oxidoreductase; 3β-hydroxysteroid:oxygen oxidoreductase; 9028-76-6. Enzyme Commission Number: EC 1.1.3.6. CAS No. 9028-76-6. CHOD. Mole weight: ca. 58 kDa. Activity: > 5 U/mg lyophilizate. Appearance: Yellow lyophilizate. Source: E. coli. Species: E. coli. EC 1.1.3.6, cholesterol-O2 oxidoreductase; 3β-hydroxy steroid oxidoreductase; 3β-hydroxysteroid:oxygen oxidoreductase; 9028-76-6. Cat No: DIA-406. | |
| Cholesterol oxidase from E. coli, Recombinant (liquid) | Recombinant Cholesterol Oxidase belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. This enzyme participates in bile acid biosynthesis. Group: Enzymes. Synonyms: EC 1.1.3.6, cholesterol-O2 oxidoreductase; 3β-hydroxy steroid oxidoreductase; 3β-hydroxysteroid:oxygen oxidoreductase; 9028-76-6. Enzyme Commission Number: EC 1.1.3.6. CAS No. 9028-76-6. CHOD. Mole weight: ca. 59 kDa. Activity: > 200 U/ml. Stability: stable at 25°C for at least one month. Form: Liquid form (30% sucrose solution). Source: E. coli. Species: E. coli. EC 1.1.3.6, cholesterol-O2 oxidoreductase; 3β-hydroxy steroid oxidoreductase; 3β-hydroxysteroid:oxygen oxidoreductase; 9028-76-6. Cat No: DIA-408. | |
| Cholesterol Oxidase from Microorganism | Cholesterol oxidase (CHOD) is a monomeric flavoprotein containing FAD that catalyzes the first step in cholesterol catabolism. This bifunctional enzyme oxidizes cholesterol to cholest-5-en-3-one in an FAD-requiring step, which is then isomerized to cholest-4-en-3-one with the release of H2O2. Group: Enzymes. Synonyms: Cholesterol-O2 oxidoreductase; 3 beta-Hydroxy steroid oxidoreductase; 3β-hydroxysteroid: oxygen oxidoreductase; cholesterol: oxygen oxidoreductase; cholesterol oxidase; EC 1.1.3.6. Enzyme Commission Number: EC 1.1.3.6. CAS No. 9028-76-6. Activity: 12U/mg-solid or more. Form: Freeze dried powder. Source: Microorganism. Cholesterol-O2 oxidoreductase; 3 beta-Hydroxy steroid oxidoreductase; 3β-hydroxysteroid: oxygen oxidoreductase; cholesterol: oxygen oxidoreductase; cholesterol oxidase; EC 1.1.3.6. Cat No: DIA-138. | |
| Cholesterol oxidase from Nocardia sp., Recombinant | Cholesterol oxidase (CHOD) is a monomeric flavoprotein containing FAD that catalyzes the first step in cholesterol catabolism. This bifunctional enzyme oxidizes cholesterol to cholest-5-en-3-one in an FAD-requiring step, which is then isomerized to cholest-4-en-3-one with the release of H2O2. Group: Enzymes. Synonyms: EC 1.1.3.6, cholesterol-O2 oxidoreductase; 3β-hydroxy steroid oxidoreductase; 3β-hydroxysteroid:oxygen oxidoreductase; 9028-76-6. Enzyme Commission Number: EC 1.1.3.6. CAS No. 9028-76-6. CHOD. Activity: > 20 Units / mg. Storage: Below -20°C. Form: Lyophilized powder. Source: E. coli. Species: Nocardia sp. EC 1.1.3.6, cholesterol-O2 oxidoreductase; 3β-hydroxy steroid oxidoreductase; 3β-hydroxysteroid:oxygen oxidoreductase; 9028-76-6. Cat No: NATE-1033. | |
| Cholesterol Oxidase from Streptomyces sp. | Cholesterol oxidase (CHOD) is a monomeric flavoprotein containing FAD that catalyzes the first step in cholesterol catabolism. This bifunctional enzyme oxidizes cholesterol to cholest-5-en-3-one in an FAD-requiring step, which is then isomerized to cholest-4-en-3-one with the release of H2O2. Group: Enzymes. Synonyms: EC 1.1.3.6, cholesterol-O2 oxidoreductase; 3β-hydroxy steroid oxidoreductase; 3β-hydroxysteroid:oxygen oxidoreductase; 9028-76-6. Enzyme Commission Number: EC 1.1.3.6. CAS No. 9028-76-6. Activity: 15U/mg-solid or more. Storage: -20°C. Form: Freeze dried powder. Source: Streptomyces sp. EC 1.1.3.6, cholesterol-O2 oxidoreductase; 3β-hydroxy steroid oxidoreductase; 3β-hydroxysteroid:oxygen oxidoreductase; 9028-76-6. Cat No: NATE-0128. | |
| Cholesterol Oxidase, PEG Modified | PEG (Polyethylene glycol) modified cholesterol oxidase (Cholesterol oxidase PEG) is one of our premier cholesterol oxidase conjugates. Cholesterol oxidase is an enzyme that catalyzes the oxidation of cholesterol by oxygen into cholest-4-en-3-one and H2O2. This enzyme belongs to the family of oxidoreductases. Cholesterol oxidase has been used widely in the determination of serum cholesterol combined with other enzymes. PEG modified cholesterol oxidase provides better stability of this enzyme without major compromising its bioactivity. All our labeled cholesterol oxidase products were performed under mild reaction conditions to retain their maximum bioactivity. These conjugates were further purified by chromatography to ensure adequate applications both in-vitro and in-vivo. Conjugate ration: 20~50 peg5000r. solubility: soluble in aqueous buffer. Group: Enzymes. Synonyms: PEG Cholesterol Oxidase; Cholesterol Oxidase-polyethylene glycol; CHOD-polyethylene glycol; CHOD-PEG; PEG-CHOD; PEG-Cholesterol Oxidase. CHOD. Mole weight: ~61.8 kD. Activity: >10 units/mg solid. Storage: Store at -20°C. Form: Lyophilized powder. Source: Microorganism. PEG Cholesterol Oxidase; Cholesterol Oxidase-polyethylene glycol; CHOD-polyethylene glycol; CHOD-PEG; PEG-CHOD; PEG-Cholesterol Oxidase; Cholesterol Oxidase, PEG Modified. Cat No: NATE-1588. | |
| choline dehydrogenase | A quinoprotein. In many bacteria, plants and animals, the osmoprotectant betaine is synthesized using different enzymes to catalyse the conversion of (1) choline into betaine aldehyde and (2) betaine aldehyde into betaine. In plants, the first reaction is catalysed by EC 1.14.15.7, choline monooxygenase, whereas in animals and many bacteria, it is catalysed by either membrane-bound choline dehydrogenase (EC 1.1.99.1) or soluble choline oxidase (EC 1.1.3.17). The enzyme involved in the second step, EC 1.2.1.8, betaine-aldehyde dehydrogenase, appears to be the same in plants, animals and bacteria. Group: Enzymes. Synonyms: choline oxidase; choline-cytochrome c reductase; choline:(acceptor) oxidoreductase; choline:(acceptor) 1-oxidoreductase. Enzyme Commission Number: EC 1.1.99.1. CAS No. 9028-67-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0443; choline dehydrogenase; EC 1.1.99.1; 9028-67-5; choline oxidase; choline-cytochrome c reductase; choline:(acceptor) oxidoreductase; choline:(acceptor) 1-oxidoreductase. Cat No: EXWM-0443. | |
| choline kinase | Ethanolamine and its methyl and ethyl derivatives can also act as acceptors. Group: Enzymes. Synonyms: choline kinase (phosphorylating); choline phosphokinase; choline-ethanolamine kinase. Enzyme Commission Number: EC 2.7.1.32. CAS No. 9026-67-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3063; choline kinase; EC 2.7.1.32; 9026-67-9; choline kinase (phosphorylating); choline phosphokinase; choline-ethanolamine kinase. Cat No: EXWM-3063. | |
| Choline Kinase (Crude Enzyme) | Choline kinase (also known as CK,ChoK and choline phosphokinase) is an enzyme which catalyzes the first reaction in the choline pathway for phosphatidylcholine (PC) biosynthesis. This reaction involves the transfer of a phosphate group from adenosine triphosphate (ATP) to choline in order to form phosphocholine. Thus, the two substrates of this enzyme are ATP and choline, whereas its two products are adenosine diphosphate (ADP) and O-phosphocholine. Choline kinase requires magnesium ions (+2) as a cofactor for this reaction. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol grou. CHKA and CHKB and are only active in their homodimeric, heterodimeric and oligomeric forms. This product with the indicated enzyme activity was briefly purified from engineered E. coli. Applications: Biotechnology; diagnostics; drug development; medicine. Group: Enzymes. Synonyms: Choline Kinase (phosphorylating); choline phosphokinase; choline-ethanolamine kinase. Enzyme Commission Number: EC 2.7.1.32. CAS No. 9026-67-9. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. Choline Kinase (phosphorylating); choline phosphokinase; choline-ethanolamine kinase. Pack: 100ml. Cat No: NATE-1825. | |
| choline monooxygenase | The spinach enzyme, which is located in the chloroplast, contains a Rieske-type [2Fe-2S] cluster, and probably also a mononuclear Fe centre. Requires Mg2+. Catalyses the first step of glycine betaine synthesis. In many bacteria, plants and animals, betaine is synthesized in two steps: (1) choline to betaine aldehyde and (2) betaine aldehyde to betaine. Different enzymes are involved in the first reaction. In plants, the reaction is catalysed by this enzyme whereas in animals and many bacteria it is catalysed by either membrane-bound EC 1.1.99.1 (choline dehydrogenase) or soluble EC 1.1.3.17 (choline oxidase). The enzyme involved in the second step, EC 1.2.1.8 (betaine-aldehyde dehydrogenase), appears to be the same in plants, animals and bacteria. In some bacteria, betaine is synthesized from glycine through the actions of EC 2.1.1.156 (glycine/sarcosine N-methyltransferase) and EC 2.1.1.157 (sarcosine/dimethylglycine N-methyltransferase). Group: Enzymes. Enzyme Commission Number: EC 1.14.15.7. CAS No. 118390-76-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0950; choline monooxygenase; EC 1.14.15.7; 118390-76-4. Cat No: EXWM-0950. | |
| choline O-acetyltransferase | Propanoyl-CoA can act, more slowly, in place of acetyl-CoA. Group: Enzymes. Synonyms: choline acetylase; choline acetyltransferase. Enzyme Commission Number: EC 2.3.1.6. CAS No. 9012-78-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2239; choline O-acetyltransferase; EC 2.3.1.6; 9012-78-6; choline acetylase; choline acetyltransferase. Cat No: EXWM-2239. | |
| choline oxidase | A flavoprotein (FAD). In many bacteria, plants and animals, the osmoprotectant betaine is synthesized using different enzymes to catalyse the conversion of (1) choline into betaine aldehyde and (2) betaine aldehyde into betaine. In plants, the first reaction is catalysed by EC 1.14.15.7, choline monooxygenase, whereas in animals and many bacteria, it is catalysed by either membrane-bound choline dehydrogenase (EC 1.1.99.1) or soluble choline oxidase (EC 1.1.3.17). The enzyme involved in the second step, EC 1.2.1.8, betaine-aldehyde dehydrogenase, appears to be the same in those plants, animals and bacteria that use two separate enzymes. Group: Enzymes. Enzyme Commission Number: EC 1.1.3.17. CAS No. 9028-67-5. Choline Oxidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0399; choline oxidase; EC 1.1.3.17; 9028-67-5. Cat No: EXWM-0399. | |
| choline-phosphate cytidylyltransferase | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). This enzyme participates in aminophosphonate metabolism and glycerophospholipid metabolism. Group: Enzymes. Synonyms: phosphorylcholine transferase; CDP-choline pyrophosphorylase; CDP-choline synthetase; choline phosphate cytidylyltransferase; CTP-phosphocholine cytidylyltransferase; CTP:phosphorylcholine cytidylyltransferase; cytidine diphosphocholine pyrophosphorylase; phosphocholine cytidylyltransferase; phosphorylcholine cytidylyltransferase; phosphorylcholine:CTP cytidylyltransferase. Enzyme Commission Number: EC 2.7.7.15. CAS No. 9026-34-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3231; choline-phosphate cytidylyltransferase; EC 2.7.7.15; 9026-34-0; phosphorylcholine transferase; CDP-choline pyrophosphorylase; CDP-choline synthetase; choline phosphate cytidylyltransferase; CTP-phosphocholine cytidylyltransferase; CTP:phosphorylcholine cytidylyltransferase; cytidine diphosphocholine pyrophosphorylase; phosphocholine cytidylyltransferase; phosphorylcholine cytidylyltransferase; phosphorylcholine:CTP cytidylyltransferase. Cat No: EXWM-3231. | |
| Choline-Phosphate Cytidylyltransferase (Crude Enzyme) | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). This enzyme participates in aminophosphonate metabolism and glycerophospholipid metabolism. This product with the indicated enzyme activity was briefly purified from engineered E. coli. Applications: Medicine. Group: Enzymes. Synonyms: phosphorylcholine transferase; CDP-choline pyrophosphorylase; CDP-choline synthetase; choline phosphate cytidylyltransferase; CTP-phosphocholine cytidylyltransferase; CTP:phosphorylcholine cytidylyltransferase; cytidine diphosphocholine pyrophosphorylase; phosphocholine cytidylyltransferase; phosphorylcholine cytidylyltransferase; phosphorylcholine: Enzyme Commission Number: EC 2.7.7.15. CAS No. 9026-34-0. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. phosphorylcholine transferase; CDP-choline pyrophosphorylase; CDP-choline synthetase; choline phosphate cytidylyltransferase; CTP-phosphocholine cytidylyltransferase; CTP:phosphorylcholine cytidylyltransferase; cytidine diphosphocholine pyrophosphorylase; phosphocholine cytidylyltransferase; phosphorylcholine cytidylyltransferase; phosphorylcholine:CTP cytidylyltransferase. Pack: 100ml. Cat No: NATE-1831. | |
| cholinesterase | Acts on a variety of choline esters and a few other compounds. Group: Enzymes. Synonyms: pseudocholinesterase; butyrylcholine esterase; non-specific cholinesterase; choline esterase II (unspecific); benzoylcholinesterase; choline esterase; butyrylcholinesterase; propionylcholinesterase; BtChoEase. Enzyme Commission Number: EC 3.1.1.8. CAS No. 9001-8-5. BCHE. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3508; cholinesterase; EC 3.1.1.8; 9001-08-5; pseudocholinesterase; butyrylcholine esterase; non-specific cholinesterase; choline esterase II (unspecific); benzoylcholinesterase; choline esterase; butyrylcholinesterase; propionylcholinesterase; BtChoEase. Cat No: EXWM-3508. | |
| choline-sulfatase | This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. Group: Enzymes. Enzyme Commission Number: EC 3.1.6.6. CAS No. 9025-59-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3756; choline-sulfatase; EC 3.1.6.6; 9025-59-6. Cat No: EXWM-3756. | |
| choline sulfotransferase | This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:choline sulfotransferase. This enzyme is also called choline sulphokinase. This enzyme participates in sulfur metabolism. Group: Enzymes. Synonyms: choline sulphokinase. Enzyme Commission Number: EC 2.8.2.6. CAS No. 9047-23-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3400; choline sulfotransferase; EC 2.8.2.6; 9047-23-8; choline sulphokinase. Cat No: EXWM-3400. | |
| choline trimethylamine-lyase | The enzyme utilizes a glycine radical to break the C-N bond in choline. Found in choline-degrading anaerobic bacteria. Group: Enzymes. Synonyms: cutC (gene name). Enzyme Commission Number: EC 4.3.99.4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5311; choline trimethylamine-lyase; EC 4.3.99.4; cutC (gene name). Cat No: EXWM-5311. | |
| choloyl-CoA hydrolase | Also acts on chenodeoxycholoyl-CoA and to a lesser extent on short- and medium- to long-chain acyl-CoAs, and other substrates, including trihydroxycoprostanoyl-CoA, hydroxymethylglutaryl-CoA and branched chain acyl-CoAs, all of which are present in peroxisomes. The enzyme is strongly inhibited by CoA and may be involved in controlling CoA levels in the peroxisome. Group: Enzymes. Synonyms: PTE-2 (ambiguous); choloyl-coenzyme A thioesterase; chenodeoxycholoyl-coenzyme A thioesterase; peroxisomal acyl-CoA thioesterase 2. Enzyme Commission Number: EC 3.1.2.27. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3560; choloyl-CoA hydrolase; EC 3.1.2.27; PTE-2 (ambiguous); choloyl-coenzyme A thioesterase; chenodeoxycholoyl-coenzyme A thioesterase; peroxisomal acyl-CoA thioesterase 2. Cat No: EXWM-3560. | |
| choloylglycine hydrolase | Also acts on the 3α,12α-dihydroxy-derivative, and on choloyl-taurine. Group: Enzymes. Synonyms: glycocholase; bile salt hydrolase; choloyltaurine hydrolase; 3α,7α,12α-trihydroxy-5β-cholan-24-oylglycine amidohydrolase. Enzyme Commission Number: EC 3.5.1.24. CAS No. 37289-07-9. Choloylglycine Hydrolase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4414; choloylglycine hydrolase; EC 3.5.1.24; 37289-07-9; glycocholase; bile salt hydrolase; choloyltaurine hydrolase; 3α,7α,12α-trihydroxy-5β-cholan-24-oylglycine amidohydrolase. Cat No: EXWM-4414. | |
| chondro-4-sulfatase | Also acts on the saturated analogue but not on higher oligosaccharides, nor any 6-sulfates. Group: Enzymes. Synonyms: chondroitin-4-sulfatase; 4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase. Enzyme Commission Number: EC 3.1.6.9. CAS No. 9045-75-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3759; chondro-4-sulfatase; EC 3.1.6.9; 9045-75-4; chondroitin-4-sulfatase; 4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase. Cat No: EXWM-3759. | |
| chondro-6-sulfatase | Also acts on the saturated analogue and N-acetyl-D-galactosamine 4,6-disulfate, but not higher oligosaccharides, nor any 4-sulfate. Group: Enzymes. Synonyms: 4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase. Enzyme Commission Number: EC 3.1.6.10. CAS No. 9045-76-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3743; chondro-6-sulfatase; EC 3.1.6.10; 9045-76-5; 4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase. Cat No: EXWM-3743. | |
| chondroitin 4-sulfotransferase | The sulfation takes place at the 4-position of N-acetyl-galactosamine residues of chondroitin. Not identical with EC 2.8.2.17 chondroitin 6-sulfotransferase. Group: Enzymes. Synonyms: chondroitin sulfotransferase. Enzyme Commission Number: EC 2.8.2.5. CAS No. 83589-04-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3399; chondroitin 4-sulfotransferase; EC 2.8.2.5; 83589-04-2; chondroitin sulfotransferase. Cat No: EXWM-3399. | |
| chondroitin 6-sulfotransferase | The sulfation is at the 6-position of N-acetylgalactosamine residues of chondroitin. Not identical with EC 2.8.2.5 chondroitin 4-sulfotransferase. Group: Enzymes. Synonyms: chondroitin 6-O-sulfotransferase; 3'-phosphoadenosine 5'-phosphosulfate (PAPS):chondroitin sulfate sulfotransferase; terminal 6-sulfotransferase. Enzyme Commission Number: EC 2.8.2.17. CAS No. 37292-93-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3375; chondroitin 6-sulfotransferase; EC 2.8.2.17; 37292-93-6; chondroitin 6-O-sulfotransferase; 3'-phosphoadenosine 5'-phosphosulfate (PAPS):chondroitin sulfate sulfotransferase; terminal 6-sulfotransferase. Cat No: EXWM-3375. | |
| Chondroitin ABC lyase from Bacteroides thetaiotaomicron, Recombinant | Chondroitinase ABC is an enzyme from Bacteroides thetaiotaomicron that cleaves the endo-1,4-β-galactosaminic bonds between acetylgalactosamine and either glucuronic or iduronic acid. Group: Enzymes. Synonyms: chondroitinase; chondroitin ABC eliminase; chondroitinase ABC; chondroitin ABC lyase; chondroitin sulfate ABC lyase; ChS ABC lyase; chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I; EC 4.2.2.20. Enzyme Commission Number: EC 4.2.2.20. Purity: >90% as judged by SDS-PAGE. Chondroitinase ABC. Mole weight: 47.6 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Bacteroides thetaiotaomicron. chondroitinase; chondroitin ABC eliminase; chondroitinase ABC; chondroitin ABC lyase; chondroitin sulfate ABC lyase; ChS ABC lyase; chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I; EC 4.2.2.20. Cat No: NATE-1548. | |
| chondroitin AC lyase | Acts on chondroitin 4-sulfate and chondroitin 6-sulfate, but less well on hyaluronate. In general, chondroitin sulfate (CS) and dermatan sulfate (DS) chains comprise a linkage region, a chain cap and a repeat region. The repeat region of CS is a repeating disaccharide of glucuronic acid (GlcA) and N-acetylgalactosamine (GalNAc) [-4)GlcA(β1-3)GalNAc(β1-]n, which may be O-sulfated on the C-4 and/or C-6 of GalNAc and C-2 of GlcA. GlcA residues of CS may be epimerized to iduronic acid (IdoA) forming the repeating disaccharide [-4)IdoA(α1-3)GalNAc(β1-]n of DS. Both the concentrations and locations of sulfate-ester substituents vary with glucosaminoglycan source. Group: Enzymes. Synonyms: chondroitinase (ambiguous); chondroitin sulfate lyase; chondroitin AC eliminase; chondroitinase AC; ChnAC. Enzyme Commission Number: EC 4.2.2.5. CAS No. 9047-57-8. ChnAC. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5104; chondroitin AC lyase; EC 4.2.2.5; 9047-57-8; chondroitinase (ambiguous); chondroitin sulfate lyase; chondroitin AC eliminase; chondroitinase AC; ChnAC. Cat No: EXWM-5104. | |
| Chondroitinase ABC from Proteus vulgaris, Recombinant | Chondroitinase ABC cleaves, via an elimination mechanism, sulfated and non-sulfated polysaccharide chains containing 1-4 linkages between hexosamines and glucuronic acid residues. The reaction yields oligosaccharide products (mainly disaccharides) containing unsaturated uronic acids which can be detected by UV spectroscopy at 232 nm. The enzyme is active on chondroitin sulfates A and C, chondroitin sulfates B (dermatan sulfate), chondroitin and hyaluronic acid. Applications: Determination of contents of chondroitin sulfates by hplcprocessing animal tissues before further investigationspreparation of chondroitin and hyaluronic acid derived unsaturated disaccharidespreparation of hyaluronic acid derived unsaturated disaccharide. Group: Enzymes. Synonyms: EC 4.2.2.4, chondroitinase; ch. Enzyme Commission Number: EC 4.2.2.20. CAS No. 9024-13-9. Chondroitinase ABC. Mole weight: 117.3 kDa. Activity: > 100 IU/mg (substrate: chondroitin sulfate A). Stability: Expiration is at least 12 months from manufacturing date, kept at -20 °C. Source: E.coli. Species: Proteus vulgaris. EC 4.2.2.4, chondroitinase; chondroitin ABC eliminase; chondroitinase ABC; chondroitin ABC lyase; chondroitin sulfate ABC lyase; ChS ABC lyase; chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I; 9024-13-9. Cat No: NATE-1949. | |
| Chondroitinase AC from Flavobacterium heparinum, Recombinant | Chondroitinase AC from Flavobacteriun heparinum is an eliminase that degrades chondroitin sulfates A and C, but not chondroitin sulfate B. The enzyme cleaves, via an elimination mechanism, both sulfated and non-sulfated polysaccharide chains that contain (1?4)-linkages between hexosamines and glucuronic acid residues. The reaction yields oligosaccharide products, mainly disaccharides, with unsaturated uronic acids that can be detected by UV spectroscopy at 232 nm. Applications: Chondroitinase ac was shown to inhibit melanoma invasion and proliferation, endothelial proliferation, and angiogenesis. chondroitinase ac, but not chondroitinase b, has also been shown t., and protease activities. ChnAC. Activity: >200 units/mg protein. Appearance: Powder. Storage: Store the product at -20?C. When stored properly and unopened at -20?C, the enzyme has a recommended retest date of 2 years. After reconstitution, the product may be kept at 4?C for 4 days, but it is recommended to store the solution in working aliquots at -20 ?C. Form: The enzyme is supplied as a lyophilized powder containing potassium phosphate, NaCl, and a stabilizer. Source: E. coli. Species: Flavobacterium heparinum. chondroitinase (ambiguous); chondroitin sulfate lyase; chondroitin AC eliminase; chondroitinase AC; ChnAC; 9047-57-8; EC 4.2.2.5. Cat No: NATE-1738. | |
| Chondroitinase B from Flavobacterium heparinum, Recombinant | In enzymology, a chondroitin B lyase (EC 4.2.2.19) is an enzyme that catalyzes the chemical reaction:Eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (deltaUA-GalNAc-4S). This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The enzyme cleaves, via an elimination mechanism, polysaccharide chains containing 1-4 linkages between hexosamines and iduronic acid residues in dermatan sulfate (chondroit.preparation of di-and oligo-saccharides of dermatan sulfate. Group: Enzymes. Synonyms: Chondroitinase B; EC 4.2.2.19; chondroitin B lyase; ChonB; ChnB. Enzyme Commission Number: EC 4.2.2.19. CAS No. 52227-83-5. Purity: > 90 % by reversed phase HPLC analysis. ChonB. Mole weight: 54,779 Da. Activity: > 550 IU/mg (substrate: dermatan sulfate). Stability: Expiration is 30 months from manufacturing date, frozen at -70°C in aqueous buffers containing Sodium Chloride, Sodium Phosphate and Sucrose 5%. Source: Flavobacterium heparinum. Species: Flavobacterium heparinum. Chondroitinase B; EC 4.2.2.19; chondroitin B lyase; ChonB; ChnB. Pack: vial of 5 ug. Cat No: NATE-0130. | |
| chondroitin B lyase | This is the only lyase that is known to be specific for dermatan sulfate as substrate. The minimum substrate length required for catalysis is a tetrasaccharide. In general, chondroitin sulfate (CS) and dermatan sulfate (DS) chains comprise a linkage region, a chain cap and a repeat region. The repeat region of CS is a repeating disaccharide of glucuronic acid (GlcA) and N-acetylgalactosamine (GalNAc) [-4)GlcA(β1-3)GalNAc(β1-]n, which may be O-sulfated on the C-4 and/or C-6 of GalNAc and C-2 of GlcA. GlcA residues of CS may be epimerized to iduronic acid (IdoA) forming the repeating disaccharide [-4)IdoA(α1-3)GalNAc(β1-]n of DS. Both the concentrations and locations of sulfate-ester substituents vary with glucosaminoglycansource. Group: Enzymes. Synonyms: chondroitinase B; ChonB; ChnB. Enzyme Commission Number: EC 4.2.2.19. CAS No. 52227-83-5. ChonB. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5094; chondroitin B lyase; EC 4.2.2.19; 52227-83-5; chondroitinase B; ChonB; ChnB. Cat No: EXWM-5094. | |
| chondroitin-glucuronate 5-epimerase | Not identical with EC 5.1.3.17 heparosan-N-sulfate-glucuronate 5-epimerase. Group: Enzymes. Synonyms: polyglucuronate 5-epimerase; dermatan-sulfate 5-epimerase; urunosyl C-5 epimerase; chondroitin D-glucuronosyl 5-epimerase. Enzyme Commission Number: EC 5.1.3.19. CAS No. 70766-66-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5404; chondroitin-glucuronate 5-epimerase; EC 5.1.3.19; 70766-66-4; polyglucuronate 5-epimerase; dermatan-sulfate 5-epimerase; urunosyl C-5 epimerase; chondroitin D-glucuronosyl 5-epimerase. Cat No: EXWM-5404. | |
| chondroitin-sulfate-ABC endolyase | This enzyme degrades a variety of glycosaminoglycans of the chondroitin-sulfate- and dermatan-sulfate type. Chondroitin sulfate, chondroitin-sulfate proteoglycan and dermatan sulfate are the best substrates but the enzyme can also act on hyaluronan at a much lower rate. Keratan sulfate, heparan sulfate and heparin are not substrates. In general, chondroitin sulfate (CS) and dermatan sulfate (DS) chains comprise a linkage region, a chain cap and a repeat region. The repeat region of CS is a repeating disaccharide of glucuronic acid (GlcA) and N-acetylgalactosamine (GalNAc) [-4)GlcA(β1-3)GalNAc(β1-]n, which may be O-sulfated on the C-4 and/or C-6 of GalNAc and C-2 of.ous); chondroitin ABC lyase (ambiguous);chondroitin sulfate ABC lyase (ambiguous); ChS ABC lyase (ambiguous); chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I. Enzyme Commission Number: EC 4.2.2.20. CAS No. 9024-13-9. Chondroitinase ABC. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5096; chondroitin-sulfate-ABC endolyase; EC 4.2.2.20; 9024-13-9; chondroitinase (ambiguous); chondroitin ABC eliminase (ambiguous); chondroitinase ABC (ambiguous); chondroitin ABC lyase (ambiguous);chondroitin sulfate ABC lyase (ambiguous); ChS ABC lyase (ambiguous); cho. | |
| chondroitin-sulfate-ABC exolyase | This enzyme degrades a variety of glycosaminoglycans of the chondroitin-sulfate- and dermatan-sulfate type. Chondroitin sulfate, chondroitin-sulfate proteoglycan and dermatan sulfate are the best substrates but the enzyme can also act on hyaluronan at a much lower rate. Keratan sulfate, heparan sulfate and heparin are not substrates. The related enzyme EC 4.2.2.20, chondroitin-sulfate-ABC endolyase, has the same substrate specificity but produces a mixture of oligosaccharides of different sizes that are ultimately degraded totetra- and disaccharides. Both enzymes act by the removal of a relatively acidic C-5 proton of the uronic acid followed by the elimination of a 4-linked.C lyase (ambiguous); chondroitin sulfate ABC exoeliminase; chondroitin sulfate ABC exolyase; ChS ABC lyase II. Enzyme Commission Number: EC 4.2.2.21. CAS No. 1000607-06-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5097; chondroitin-sulfate-ABC exolyase; EC 4.2.2.21; 1000607-06-6; chondroitinase (ambiguous); chondroitin ABC eliminase (ambiguous); chondroitinase ABC (ambiguous); chondroitin ABC lyase (ambiguous);chondroitin sulfate ABC lyase (ambiguous); ChS ABC lyase (ambiguous); chondroitin sulfate ABC exoeliminase; chondroitin sulfate ABC exolyase; ChS ABC lyase II. Cat No: EXWM-5097. | |
| Chondroitin synthase from Pasteurella multocida, Recombinant | In enzymology, a N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase (EC 2.4.1.226) is an enzyme that catalyzes the chemical reaction: UDP-alpha-D-glucuronate + N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl- proteoglycan ? UDP + beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)- beta-D-glucuronosyl-proteoglycan. The 3 substrates of this enzyme are UDP-alpha-D-glucuronate, [[N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-]], and proteoglycan, whereas its 3 products are UDP, [[beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-]], and beta-D-glucuronosyl-proteoglycan. Group: Enzymes. Synonyms: alpha-D-glucuronate:N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glu curonosyl-proteoglycan 3-beta-glucuronosyltransferase; chondroitin glucuronyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferas. Enzyme Commission Number: EC 2.4.1.226. CAS No. 269077-98-7. Purity: min 95% by SDS-PAGE. Chondroitin synthase. Source: E. coli. Species: Pasteurella multocida. alpha-D-glucuronate:N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glu curonosyl-proteoglycan 3-beta-glucuronosyltransferase; chondroitin glucuronyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase; EC 2.4.1.226; Chondroitin synthase. Cat No: NATE-1486. | |
| choriolysin H | Known from the teleost fish Oryzias latipes (medaka). Efficient dissolution of the egg membrane requires concerted action with choriolysin L. A 25.5 kDa peptidase in family M12 (astacin family). Group: Enzymes. Synonyms: teleost hatching enzyme (component); high choriolytic enzyme (HCE). Enzyme Commission Number: EC 3.4.24.67. CAS No. 177529-16-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4350; choriolysin H; EC 3.4.24.67; 177529-16-7; teleost hatching enzyme (component); high choriolytic enzyme (HCE). Cat No: EXWM-4350. | |
| choriolysin L | Known from the teleost fish Oryzias latipes (medaka). Efficient dissolution of the egg membrane requires concerted action with choriolysin H. A 24 kDa peptidase family M12 (astacin family). Group: Enzymes. Synonyms: teleost hatching enzyme (component); low choriolytic enzyme (LCE). Enzyme Commission Number: EC 3.4.24.66. CAS No. 177529-15-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4349; choriolysin L; EC 3.4.24.66; 177529-15-6; teleost hatching enzyme (component); low choriolytic enzyme (LCE). Cat No: EXWM-4349. | |
| chorismatase | The enzyme found in several bacterial species is involved in the biosynthesis of macrocyclic polyketides. Group: Enzymes. Synonyms: chorismate/3,4-dihydroxycyclohexa-1,5-dienoate synthase; fkbO (gene name); rapK (gene name). Enzyme Commission Number: EC 3.3.2.13. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3998; chorismatase; EC 3.3.2.13; chorismate/3,4-dihydroxycyclohexa-1,5-dienoate synthase; fkbO (gene name); rapK (gene name). Cat No: EXWM-3998. | |
| chorismate dehydratase | The enzyme, found in several bacterial species, is part of the futalosine pathway for menaquinone biosynthesis. Group: Enzymes. Synonyms: MqnA. Enzyme Commission Number: EC 4.2.1.151. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4992; chorismate dehydratase; EC 4.2.1.151; MqnA. Cat No: EXWM-4992. | |
| chorismate lyase | This enzyme catalyses the first step in the biosynthesis of ubiquinone in Escherichia coli and other Gram-negative bacteria. The yeast Saccharomyces cerevisiae can synthesize ubiquinone from either chorismate or tyrosine. Group: Enzymes. Synonyms: CL; CPL; UbiC. Enzyme Commission Number: EC 4.1.3.40. CAS No. 157482-18-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4917; chorismate lyase; EC 4.1.3.40; 157482-18-3; CL; CPL; UbiC. Cat No: EXWM-4917. | |
| chorismate mutase | In enzymology, a chorismate mutase (EC 5.4.99.5) is an enzyme that catalyzes the chemical reaction for the conversion of chorismate to prephenate in the pathway to the production of phenylalanine and tyrosine, also known as the shikimate pathway. Group: Enzymes. Synonyms: hydroxyphenylpyruvate synthase. Enzyme Commission Number: EC 5.4.99.5. CAS No. 9068-30-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5592; chorismate mutase; EC 5.4.99.5; 9068-30-8; hydroxyphenylpyruvate synthase. Cat No: EXWM-5592. | |
| chorismate synthase | Requires FMN. The reaction goes via a radical mechanism that involves reduced FMN and its semiquinone (FMNH?). Shikimate is numbered so that the double-bond is between C-1 and C-2, but some earlier papers numbered the ring in the reverse direction. Group: Enzymes. Synonyms: 5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase. Enzyme Commission Number: EC 4.2.3.5. CAS No. 9077-07-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5209; chorismate synthase; EC 4.2.3.5; 9077-07-0; 5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase. Cat No: EXWM-5209. | |
| Chrysanthemum Extract | Chrysanthemum extract is prepared from ried flower bud of Chrysanthemum morifolium Ramat. Chrysanthemum flower extract has good health care value and can be used both as food and as medicine according to Chinese regulation. Chrysanthemum extract contains the flavanone class, the choline, the amino acid, the chrysanthemum glucoside, the chlorogenic acid and so on. Chrysanthemum extract can be used to lower fever, to detoxicate, to treat disorders of the liver, to lower blood pressure. Group: Others. Chrysanthemum Extract; Dendranthema morifolium (Ramat.) Tzvel. Cat No: EXTC-026. | |
| chrysanthemyl diphosphate synthase | Requires a divalent metal ion for activity, with Mg2+ being better than Mn2+. Chrysanthemyl diphosphate is a monoterpene with a non-head-to-tail linkage. It is unlike most monoterpenoids, which are derived from geranyl diphosphate and have isoprene units that are linked head-to-tail. The mechanism of its formation is similar to that of the early steps of squalene and phytoene biosynthesis. Chrysanthemyl diphosphate is the precursor of chrysanthemic acid, the acid half of the pyrethroid insecticides found in chrysanthemums. Group: Enzymes. Synonyms: CPPase. Enzyme Commission Number: EC 2.5.1.67. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2804; chrysanthemyl diphosphate synthase; EC 2.5.1.67; CPPase. Cat No: EXWM-2804. | |
| chymase | In mast cell granules. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase, chymase; skeletal muscle (SK) protease. Enzyme Commission Number: EC 3.4.21.39. CAS No. 97501-92-3. CMA1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4133; chymase; EC 3.4.21.39; 97501-92-3; mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase, chymase; skeletal muscle (SK) protease. Cat No: EXWM-4133. | |
| Chymase from Human, Recombinant | Chymases are a family of serine proteases found primarily in mast cells, though also present in basophil granulocytes (e.g. alpha chymase mcpt8). They show broad peptidolytic activity and are involved in a variety of functions. For example, chymases are released by mucosal mast cells upon challenge with parasites and parasite antigens promoting an inflammatory response. Chymases are also known to convert angiotensin I to angiotensin II and thus play a role in hypertension and atherosclerosis. Because of its role in inflammation it has been investigated as a target in the treatment of asthma. Applications: Chymase has been implicated in generation of angiotensin ii and cleavag. Synonyms: mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase, chymase; skeletal muscle (SK) protease; chymase; EC 3.4.21.39; 97501-92-3. Enzyme Commission Number: EC 3.4.21.39. CAS No. 97501-92-3. Purity: >90% (SDS-PAGE). CMA1. Mole weight: ~30 kDa. Activity: >40 units/mg protein. Storage: Store at -20°C. Form: Supplied as a solution in 20 mM Tris, 0.8 M NaCl and 25% glycerol, pH 7.6. Source: Pichia pastoris. Species: Human. mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase, chymase; skeletal muscle (SK) protease; chymase; EC 3.4.21.39; 97501-92-3. Cat No: NATE-0817. | |
| chymopapain | The major endopeptidase of papaya (Carica papaya) latex. It has multiple chromatographic forms. In peptidase family C1 (papain family). Group: Enzymes. Synonyms: chymopapain A; chymopapain B; chymopapain S. Enzyme Commission Number: EC 3.4.22.6. CAS No. 9001-9-6. Chymopapain. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4235; chymopapain; EC 3.4.22.6; 9001-09-6; chymopapain A; chymopapain B; chymopapain S. Cat No: EXWM-4235. | |
| chymosin | Neonatal gastric enzyme with high milk clotting and weak general proteolytic activity, formed from prochymosin. Found among mammals with postnatal uptake of immunoglobulins. In peptidase family A1(pepsin A family). Group: Enzymes. Synonyms: rennin (but this should be avoided since it leads to confusion with renin). Enzyme Commission Number: EC 3.4.23.4. CAS No. 9001-98-3. Rennin. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4276; chymosin; EC 3.4.23.4; 9001-98-3; rennin (but this should be avoided since it leads to confusion with renin). Cat No: EXWM-4276. | |
| Chymotrypsin | Chymotrypsin is a proteolytic enzyme. It can priority hydrolyze tyrosine containing l-isomer, phenylalanine and the peptide bond of tryptophan, the best effective condition is pH 8.0. Its activity can be restrained by heavy metal or natural trypsin inhibitor in some degrees. Applications: Practically used to heal cicatrisation caused by injuries, inflammation and it is also used for avoiding part dropsy, blood-gathering, haematoma caused by wrick, breast dropsy after operation, tympanitis and rhinitis brief introduction of production: the high purity chymotrypsin is extracted from bovine or porcine pancreas and purified by affinity chromatography in order to avoid being polluted by other protease. Group: Enzymes. Synonyms: Chymotrypsin; Alpha-chymotrypsin; Chymotrypsin A; Chymotrypsin B. CAS No. 9004-7-3. Chymotrypsin. Appearance: inquire. Chymotrypsin; Alpha-chymotrypsin; Chymotrypsin A; Chymotrypsin B. Pack: inquire. Cat No: BIO-1012. | |
| chymotrypsin C | Formed from pig chymotrypsinogen C, and from cattle subunit II of procarboxypeptidase A. Reacts more readily with Tos-Leu-CH2Cl than Tos-Phe-CH2Cl in contrast to chymotrypsin. In peptidase family S1 (trypsin family). Group: Enzymes. Enzyme Commission Number: EC 3.4.21.2. CAS No. 9036-9-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4119; chymotrypsin C; EC 3.4.21.2; 9036-09-3. Cat No: EXWM-4119. | |
| Chymotrypsin from Human, Recombinant | Chymotrypsin is a recombinant serine endopeptidase expressed in E.coli, purified with HPLC, the gene sequence is the same as human chymotrypsin. Recombinant chymotrypsin hydrolyzes at the carboxyl side of aromatic amino acids residues: Tyr, Phe and Trp. Cleavage may also be observed, but at a lower rate, at Leu and Met. Chymotrypsin activity is optimal in pH 7.0-9.0. Applications: Hydrolysis of proteins by chymotrypsin alone or in combination with other proteases. suitable for peptide mapping, fingerprinting, and sequence analysis. Group: Enzymes. Synonyms: EC 3.4.21.1; chymotrypsins A and B; alpha-chymar ophth; avazyme; chymar; chymotest; enzeon; quimar; quimotrase; alpha-chymar; alpha-chymotrypsin A; alpha-chymotrypsin; Chymotrypsin; &alpha. Enzyme Commission Number: EC 3.4.21.1. CAS No. 9004-7-3. Purity: > 95% by HPLC. Chymotrypsin. Mole weight: 26,950 Da. Activity: >1000 unit/mg protein. Storage: Recombinant Chymotrypsin lyophilized should be stored under 2°C-8°C in sealed container. It is stable within 24 months. After dissolved, it should be stored under -20°C. Form: White lyophilized. Source: E. coli. Species: Human. EC 3.4.21.1; chymotrypsins A and B; alpha-chymar ophth; avazyme; chymar; chymotest; enzeon; quimar; quimotrase; alpha-chymar; alpha-chymotrypsin A; alpha-chymotrypsin; Chymotrypsin; α-Chymotrypsin. Cat No: NATE-1890. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.