Offer over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, and novel life-science kits for scientific use.
155 macrocyclic compounds of known activity for high-throughput, high-content screening; - A powerful tool for studying antibacterial, antiviral, and protein-protein interactions, etc. ; - Most of them are already approved, with information regarding biosafety and biological activity; - NMR and HPLC validated to ensure high purity and quality; - All compounds are available from stock supplies. Uses: Scientific use. Product Category: L9300. Categories: Macrocyclic Compounds Libraries.
A unique collection of 367 compounds targeting MAPK signaling for drug discovery in MAPK related diseases; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Targets include ERK, JNK, MEK, p38, MAPK, Raf, RSK, MNK, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1400. Categories: MAPK Inhibitor Libraries.
A unique collection of 2350 metabolic pathway-related bioactive small molecule compounds for high-throughput, high-content screening. - Targeting multiple metabolic pathways such as gluconeogenesis, lipid metabolism, nucleotide metabolism; targets include GLUT, Hexokinase, Pyruvate Kinase; ATGL, MAGL, FAAH and other metabolism-related popular targets. - Structural diversity, significant drug potency and cell penetration. - Detailed specifications, compound structure, target information, activity description, etc. - NMR, HPLC/LCMS and other detection techniques to ensure correct structure and high purity of the product and reduce false positives. Uses: Scientific use. Product Category: L2560. Categories: Metabolism Compounds Libraries.
Methylation Compound Library
125 methylation-related compounds that can be used for high-throughput and high-content screening. - Targets include DNA Methyltransferase, Histone Methyltransferase, etc. - Can be used for studies on epigenetics, differentiation, aging, cancer, etc. - Detailed instructions, compound structure, target information, activity description, etc. - NMR and HPLC analytical techniques to ensure high product purity and quality. - All compounds are available in stock. Uses: Scientific use. Product Category: L3510. Categories: Methylation Compounds Libraries.
A unique collection of 193 microbial natural products for high throughput screening (HTS) and high content screening (HCS); - Targets include alpha-glucosidase, beta-lactamase, TNF-alpha, HDAC, PKC, HSP90, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6500. Categories: Microbial Natural Product Libraries.
Microtubule-Targeted Compound Library
A unique collection of 80 microtubule-targeted compounds can be used in HTS and HCS; - Detailed compound information with structure, target, and biological activity description; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1110. Categories: Microtubule-Targeted Compounds Libraries.
Mini Electrophilic Heterocyclic Fragment Library
The theoretical basis of FBDD is to select favorable fragment combinations or extensions to obtain new drug molecules, with a higher probability of obtaining highly active drug candidates. Compared with the screening of millions of macromolecules, thousands of fragment molecules can be combined to form millions of drug structures, which are easier to collect and manage. In addition, fragments have smaller molecular weights, relatively higher solubility, and easier structural optimization. The potential of over-the-counter medicine is higher. Targeted covalent inhibitors and chemical probes have become part of drug discovery methods. Given the advantages of fragment-based drug discovery, screening electrophilic fragments has become a promising alternative to discover and verify new targets and generate viable chemical starting points, even for targets that are almost difficult to handle. In response to this situation, we designed a small library of heterocyclic electrophilic compounds. General technology for covalent fragment screening ?. Uses: Scientific use. Product Category: L7860. Categories: Mini Electrophilic Heterocyclic Fragment Libraries.
Mini Scaffold Library
Diversity: Selected from 1, 600, 000 drug-like compounds covering rich chemical scaffolds, 5033 compounds representing 5033 scaffolds?- Drug-likeness: filtering out reactive, toxic and otherwise undesirable structural motifs, and removing compounds that demonstrate a broad promiscuous activity (PAINS); - Strict quality control: more than 90% purity for each member with HNMR/LCMS validation?- Cost effective: Liquid small package is available. Uses: Scientific use. Product Category: L5600. Categories: Mini Scaffold Libraries.
A unique collection of 447 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine; - Targets include mitochondria related targets, such as ATPase, mitochondria-associated hexokinase, Bcl-2, NADP, etc. and inhibitors for the autophagy initiating factor, ULK1, also include other promising mitochondria-targeted compounds such as lonidamine, paclitaxel, etc; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5300. Categories: Mitochondria-Targeted Compounds Libraries.
A unique collection of 203 mouse metabolites, which can be used for HTS and HCS; - Effective tool for research in metabonomics; - Some compounds have been approved by the FDA or are undergoing clinical trials; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2530. Categories: Mouse Metabolite Compounds Libraries.
A unique collection of 2070 natural products included in Chinese Pharmacopoeia (CP), a powerful tool for drug development and pharmacological study; - Diversified structures: including flavonoids, polyphenols, Alkaloids, etc. ; - Detailed compound information with structure, solubility, targeted signal pathways, action sites, and biological activity description; - Clear source: known active natural products selected from animals, plants, or microorganisms with clear species information; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6800. Categories: Natural Compound Libraries in Chinese Pharmacopoeia.
Natural Product Derivatives Library
The library consists of more than 4, 000 members belonging 22 scaffolds (average 180 compounds per scaffold). - The library includes the following sub-libraries:- Cytisine-based sub-library- Matrine-based sub-library- Podophyllotoxin-based sub-library- Sub-library based on naturally occurring privileged BBS such ashydroxy-prolines, triptamine, nor-tropolone etc. - TargetMol "Beyond RO5" filters have been applied for the library population (See Phys-chem parameters for the library members). - NO Med-Chem restrictions (widely accepted and proprietary TargetMol substructure filters on reactive functionalities, toxicophoric, instability suspicions etc. ). - More than 90% purity for each library member confirmed by LC-MS or NMR analysis. Uses: Scientific use. Product Category: NY1000. Categories: Natural Product Derivatives Libraries.
Natural Product Derivatives Library for CADD
Large quantity: contains 135, 000 natural product derivatives and the number is continuously updating. Uses: Scientific use. Product Category: L6030. Categories: Natural Product Derivatives Libraries for CADD.
Natural Product Library
A unique collection of 3720 natural products that can be used for high-throughput screening and high-content screening. - Provides biological information and pharmacological information of the products, which serve as theoretical references and research basis for screening. - Clear source: a selection of known active natural products from animals, plants and microorganisms; plant species are labeled with accurate English and Latin names to facilitate your later research corroboration. - Good structural diversity: a wide range of compound structures including flavonoids and alkaloids, with detailed classification information. - NMR, HPLC/LCMS and other detection techniques to ensure the correct structure and high purity of the product and reduce false positives. Uses: Scientific use. Product Category: L6010. Categories: Natural Product Libraries.
Natural Product Library for HTS
A unique collection of 4160 pure natural products and their derivatives with known biological activity for drug discovery, pharmacological study, stem cell differentiation, fingerprint study and quality research, and can be used for high throughput screening (HTS) and high content screening (HCS); - Documentation with clear source: isolated natural products from plant, animal, microorganism, etc. - Structurally diverse: 4160 natural products, including diverse types of structures, such as alkaloids, limonoids, sequiterpenes, diterpenes, pentacyclic triterpenes, sterols, and many other representatives which provide the structural diversity inherent in this group; - Detailed compound information with structure, solubility, target, activity, IC50 value, and biological activity description; - Cost-effective and competitive price to save your fundings. Uses: Scientific use. Product Category: L6000. Categories: Natural Product Libraries for HTS.
A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening; - Targets several signaling pathways, such as Notch, MAPK, Wnt/β-catenin, mTOR, etc. ; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - tructurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L7700. Categories: Neural Regeneration Compounds Libraries.
Neuronal Signaling Compound Library
A unique collection of 2011 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Targets include 5-HT receptor, AChR, Histamine receptor, dopamine receptor, Opioid receptor, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2600. Categories: Neuronal Signaling Compounds Libraries.
Neurotransmitter Receptor Compound Library
A unique collection of 1290 neurotransmitter receptor compounds, can be used for HTS and HCS screening?- Targets include 5-HT receptor, AChR, GABA receptor, dopamine receptor, Opiod receptor, Ionotropic Glutamatergic receptor, Metabotropic Glutamatergic receptor, Purinergic receptor, etc. ?- Structurally diverse, medicinally active, and cell permeable; - Detailed information about compound structure, target, activity, etc. ?- NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2610. Categories: Neurotransmitter Receptor Compounds Libraries.
NF-κB Signaling Compound Library
A unique collection of 560 compounds targeting NF-κB signaling for high throughput screening and high content screening; - Effective tool for research in NF-κB signaling and related drug screening; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3800. Categories: NF-κB Signaling Compounds Libraries.
A unique collection of 530 nonsteroidal anti-inflammatory related compounds can be used for HTS and HCS; - Contains common NSAIDs, such as aspirin, indomethacin, ibuprofen, Sulindac, Piroxicam, etc. ?- Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4710. Categories: Nonsteroidal Anti-Inflammatory Compounds Libraries.
NO PAINS Compound Library
9555 PAINS-excluded small molecules for high-throughput screening and high-content screening. - Diverse targets with wide coverage; covers multiple disease research areas such as cancer, metabolism, immune system and cardiovascular system. - An effective tool for drug repurposing and cell-induced target screening. - Detailed instructions, compound structures, target information, activity descriptions, etc. - Structural diversity, significant druggability and cell penetration. - NMR, HPLC/ LCMS testings to ensure accurate structure and high purity. Uses: Scientific use. Product Category: L4020. Categories: NO PAINS Compounds Libraries.
A unique collection of 420 nuclear receptor signaling targeted compounds for high throughput and high content screening; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1510. Categories: Nuclear Receptor Inhibitors Libraries.
Nucleotide Compound Library
A unique collection of 255 nucleoside and nucleotide analogues, can be used for research and development of anti-viral, anti-tumor, anti-fungal, and anti-depressive drugs; - Some compounds are in the clinical trial phases or market therapeutic drugs?- Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1720. Categories: Nucleotide Compounds Libraries.
A unique collection of 320 osteogenesis related compounds for high throughput and high content screening; - Targets several signaling pathways, such as BMP-SMAD, Notch, MAPK, Wnt/β-catenin, Hedgehog, FGF, etc. ; - Effective tool for research in bone formation and related bone diseases, such as osteoporosis, bone tumor, etc. ; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable. Uses: Scientific use. Product Category: L7900. Categories: Osteogenesis Compounds Libraries.
A unique collection of 1279 compounds with defined prooxidant or antioxidant activity can be used for HTS and HCS; - Contains hydroperoxides, polyphenolics, metal chelators, thiols, thiol traps, radical scavengers, lazaroids and glutathione modulators as well as small molecule enzyme mimetics for SOD and glutathione peroxidase, and antioxidant natural products, etc. ?- Structurally diversified with potent bioactivity and cell permeable; - Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2900. Categories: Oxidation-Reduction Compounds Libraries.