USBiological 4 - Products
Worldwide
Our biochemicals, antibodies, recombinant proteins, cell culture media and molecular biology kits are used in virtually all scientific applications.From affordable research quantities to larger bulk amounts.
| Product | Description | |
|---|---|---|
| Anaphase-Promoting Complex Inhibitor Negative Control, AAME (AAME Hydrochloride) | An acetyl-L-arginine analog of TAME that serves as a negative control. TAME is an ubiquitin ligase inhibitor that specifically blocks Anaphase-Promoting Complex (APC) activation. Group: Biochemicals. Grades: Highly Purified. CAS No. 1784-05-0. Pack Sizes: 50mg. Molecular Formula: C?H??N?O? · HCl, Molecular Weight: 266.7. US Biological Life Sciences. |  Worldwide |
| Anaphase-Promoting Complex Inhibitor, TAME (TAME Hydrochloride) | TAME is a potent ubiquitin ligase inhibitor that specifically blocks Anaphase-Promoting Complex (APC) activation by directly binding to APC and disrupts the IR-tail-dependent interactions between APC and its activator proteins Cdc20 or Cdh1. It stabilizes APC substrates and is shown to inhibit cyclin proteolysis in mitotic Xenopus egg extract with an IC50=12uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 1784-03-8. Pack Sizes: 50mg. Molecular Formula: C??H??N?O?S · HCl, Molecular Weight: 378.87. US Biological Life Sciences. | Worldwide |
| a-Naphthaleneacetic acid 98+% | a-Naphthaleneacetic acid 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg, 2.5Kg. US Biological Life Sciences. | Worldwide |
| a-Naphthoflavone 99+% | a-Naphthoflavone 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| a-Naphthol 99+% (HPLC) | a-Naphthol 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 90-15-3. Pack Sizes: 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| a-Naphtholphthalein | a-Naphtholphthalein. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Andrastin A, Aspergillus fumigatus | A protein farnesyl transferase inhibitor. Displays antitumor properties. Inhibits the efflux of anticancer drugs from multidrug-resistant cancer cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 174232-42-9. Pack Sizes: 250ug, 1mg. US Biological Life Sciences. | Worldwide |
| Androstenediol 17-Acetate | Androstenediol 17-Acetate is used in synthetic preparation for direct organocatalytic stereoselective transfer hydrogenation of conjugated olefins of steroids. Androstenediol 17-Acetate is also obtained from Dehydro Epiandrosterone (D229585) which is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome. Group: Biochemicals. Grades: Highly Purified. CAS No. 5937-72-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C21H32O3, Molecular Weight: 332.48. US Biological Life Sciences. | Worldwide |
| Aniline Blue W/S, Certified 99+.9% (Dye content) | Aniline Blue W/S, Certified 99+.9% (Dye content). Group: Biochemicals. Grades: Certified Dye. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Aniline red | Aniline red. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g. US Biological Life Sciences. | Worldwide |
| Aniracetam (Memodrin, Referan, 1- (4-methoxybenzoyl) pyrrolidin-2-one, Draganon, Sarpul, Ampamet) | A positive allosteric modulator selective for AMPA receptors. Slows down AMPA receptor deactivation rate without altering the agonist potency. A leading candidate of ampakine nootropic for cognitive enhancement. Widely used in studies in a variety of brain functions (i.e. learn and memory, cognition) and disorders (depression, anxiety disorder, Alzheimer's disease, and aging). Group: Biochemicals. Grades: Highly Purified. CAS No. 72432-10-1. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Anisindione 98+% (TLC) | Anisindione 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| Anisole 99+% | Anisole 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 100-66-3. Pack Sizes: 250ml, 1L, 2.5L, 10L. US Biological Life Sciences. | Worldwide |
| Anomalin A (2,3,6,8-Tetrahydroxy-1-methylxanthone) | Originally isolated from the marine fungus Arthrinium sp., Anomalin A is a potent Lck (p56lck; lymphocyte specific tyrosine kinase) inhibitor. Also acts as an antioxidant and DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenger. Group: Biochemicals. Grades: Highly Purified. CAS No. 548740-86-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ansatrienin A (Mycotrienin I, Antibiotic T 23I) | Antibiotic. Antitumor compound. Antifungal. Inhibits osteoclastic bone resorption. Group: Biochemicals. Grades: Highly Purified. CAS No. 82189-03-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Anthranilamide 99+% (HPLC) | Anthranilamide 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg, 5Kg. US Biological Life Sciences. | Worldwide |
| Anthrarobin | Anthrarobin is a substituted polycyclic aromatic hydrocarbon. Group: Biochemicals. Grades: Highly Purified. CAS No. 577-33-3. Pack Sizes: 25g, 50g. Molecular Formula: C14H10O3, Molecular Weight: 226.23. US Biological Life Sciences. | Worldwide |
| Anthrone ACS | Anthrone ACS. Group: Biochemicals. Grades: ACS Grade. Pack Sizes: 100g, 250g, 25g. US Biological Life Sciences. | Worldwide |
| Antibiotic L-696,474 (18-Dehydroxycytochalasin H) | Natural cytochalasin derivative. Antiviral. Inhibitor of HIV-1 protease. Antifungal activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 141994-72-1. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Antibiotic PF 1052 | Antibiotic PF 1052 is a fungal metabolite originally isolated from Phoma.1,2 It is active against S. aureus, S. parvulus, and C. perfringens (MICs = 3.13, 0.78, and 0.39ug/ml, respectively), among others.1 It inhibits neutrophil migration in a wound assay using zebrafish larvae expressing GFP-labeled neutrophils, reducing pseudopodia formation and inducing rounding of neutrophils.2 Antibiotic PF 1052 is selective for neutrophil migration over macrophage migration in zebrafish larvae. It also inhibits the migration of murine neutrophils when used at concentrations of 10-20uM.References. Group: Biochemicals. Alternative Names: (E)-5-(sec-Butyl)-3-((2-(2,3-dimethyloxiran-2-yl)-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)(hydroxy)methylene)-1-methylpyrrolidine-2,4-dione. Grades: Highly Purified. CAS No. 147317-15-5. Pack Sizes: 500ug, 1mg. Molecular Formula: C26H39NO4, Molecular Weight: 429.6. US Biological Life Sciences. | Worldwide |
| APE1 Inhibitor III (Apurinic Endonuclease 1 Inhibitor III) (Apurinic/Apyrimidinic Endonuclease 1 Inhibitor III)(N-(3-(1,3-Benzo[d]thiazol-2-yl)-6-isopropyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)acetamide) | A cell-permeable benzothiazolyltetra hydrothienopyridine compound that acts as a potent, competitive, and active site targeting inhibitor of APE1 (IC50=2.0uM in a fluorescence based HTS assay; and 12uM in a radiotracer incision assay). Shown to block APE1 activity in HEK293T and HeLa cells extract (IC50=600nM) and increase genomic AP site accumulation. Potentiates the cytotoxicity of DNA-damaging alkylating agents in HeLa cells by ~3-fold. Exhibits favorable pharmacokinetic properties and desirable ADME attributes. Due to its lipophilic nature, it crosses the blood-brain barrier rather easily and shows desirable stability (t1/2=80min). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| a-Phenyllactic acid 99+% | a-Phenyllactic acid 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 515-30-0. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| a-Phenylpiperidine-2-acetamide ≥97% (HPLC) | a-Phenylpiperidine-2-acetamide ≥97% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| (+)-Aphidicolin | Antibiotic. Reversible inhibitor of eukaryotic nuclear DNA replication. Useful for cell synchronization. Blocks the cell cycle at early S phase. Prolongs the half life of DNA methyltransferase. Specific DNA polymerase alpha and delta inhibitor in eukaryotic cells and in some viruses of animal origin. Acts synergistically with vincristine and doxorubicin. Apoptosis inhibitor/inducer. Group: Biochemicals. Alternative Names: [3R-(3α, 4α, 4aα, 6a β,8 β,9 β,11a β,11b β ) ]-Tetradecahydro-3, 9-dihydroxy-4, 11b-dimethyl-8, 11a-methano-11aH-cyclohepta [a]naphthalene-4, 9-dimethanol; Aphidicolin; ICI 69653; NSC 234714; (3α, 4α, 5α, 17α)-3, 17-Dihydroxy-4-methyl-9, 15-cyclo-C, 18-dinor-14, 15-secoandrostane-4, 17-dimethanol; (3R, 4R, 4aR, 6aS, 8R, 9R, 11aS, 11bS) -Tetradecahydro-3, 9-dihydroxy-4, 11b-dimethyl-8, 11a-methano-11aH-cyclohepta [a]naphthalene-4, 9-dimethanol. Grades: Highly Purified. CAS No. 38966-21-1. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C20H34O4, Molecular Weight: 338.48. US Biological Life Sciences. | Worldwide |
| Apigenin-d5 7-Glucuronide | Apigenin-d5 7-Glucuronide is labelled Apigenin 7-Glucuronide (A726505), a metabolite of Apigenin, which induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap junction intracellular communication in liver cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C21H13D5O11, Molecular Weight: 451.39. US Biological Life Sciences. | Worldwide |
| ApoE4 Modulator, PH002 (Apolipoprotein E4 Structure Corrector, ApoE4 Structure Corrector, 4-{4-[2-(3-methyl-4-oxo-3,4-dihydro-phthalazin-1-yl)-acetylamido]-benzyl}-piperazine-1-carboxylic Acid Tert-butyl Ester) | A phthalazinone derived compound that directly binds to the 22kD amino-terminal region of apolipoprotein E4 (ApoE4) and blocks its intramolecular domain interactions in neuronal cells (IC50 = 116nM) thereby reversing the detrimental effects of ApoE4. Established to be more potent than GIND25. Restores mitochondrial functions and elevates the levels of complex IV subunit 1. Shown to increase in COX1 levels in primary neurons from NSE-ApoE4 transgenic mouse cortex and hippocampus. Shown to rescue impairments of mitochondrial motility in primary neurons from NSE-ApoE4 transgenic mice (~200nM). Also restores endoplasmic reticulum and Golgi apparatus transit of ApoE4 in cultured neurons and brings it to levels normally found in ApoE3 and ApoE4-R61T. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?, Molecular Weight: 491.6. US Biological Life Sciences. | Worldwide |
| Apolipoprotein C4, Recombinant, Human (APOC4) | Apolipoprotein C4, Recombinant, Human (APOC4). Group: Molecular Biology. Grades: Highly Purified. US Biological Life Sciences. | Worldwide |
| Apolipoprotein O, Recombinant, Human (APOO) | Apolipoprotein O, Recombinant, Human (APOO). Group: Molecular Biology. Grades: Highly Purified. US Biological Life Sciences. | Worldwide |
| a-(p-Toluenesulfonyl)-4-fluorobenzylisonitrile ≥95% (HPLC) | a-(p-Toluenesulfonyl)-4-fluorobenzylisonitrile ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| Aranciamycin | Antibiotic. Similar to steffimycin. Active against Gram-positive bacteria. Clostridium histolyticum collagenase inhibitor. Antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 72389-06-1. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| Arbidol-d6 | Arbidol-d6 is labelled Arbidol (A766000) which is a medicinal agent for treating viral infections. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C22H20D6BrClN2O3S. US Biological Life Sciences. | Worldwide |
| Arbutin 99.5+% | Arbutin 99.5+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100g, 250g, 25g, 5g. US Biological Life Sciences. | Worldwide |
| Arcaine Sulfate | Arcaine Sulfate. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
| ARE Activator, BTZO-1 (Macrophage Migration Inhibitory Factor Antagonist II, 2-Pyridin-2-yl-4H-1,3-benzothiazin-4-one, MIF Antagonist II) | A cell-permeable benzothiazinone that is shown to interact with MIF homotrimer (=68.6nM and 157nM toward human and rat MIF, respectively, at pH 7.3) via the N-terminal proline in a pH-dependent manner, limiting its inhibitory capability against MIF tautomerase activity (13% inhibition at pH 6.0; [BTZO-1] = 30uM) due to reduced MIF binding at acidic pH. Shown to protect primary rat cardiomyocytes (330nM) from apoptotic death upon serum deprivation or DOX (200nM) treatment via activation of ARE- (antioxidant response element) mediated cytoprotective genes transcription in a MIF-dependent manner. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H?N?OS, Molecular Weight: 240.3. US Biological Life Sciences. | Worldwide |
| Arg-Asp-OH ≥97% (HPLC) | Arg-Asp-OH ≥97% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| Arg-Tyr-OH·AcOH 98+% (HPLC) | Arg-Tyr-OH·AcOH 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 74863-12-0(net). Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
| Arsenazo III | Arsenazo III is used for the determination of Ca2+ in micromolar amounts, to investigate calcium transport in permeabilized cells and for the determination of serum calcium. Spectrophotometric reagent for U, Th, Zr and other metals. Indicator for the precipitation titration of SO4 with Ba. Group: Biochemicals. Alternative Names: 3,6-Bis[2-(2-arsonophenyl)diazenyl]-4,5-dihydroxy-2,7-naphthalenedisulfonic Acid; 2,7-Bis(2,2'-arsonophenylazo)-1,8-dihydroxynaphthalene-3,6-disulfonic Acid; 2,7-Bis(2-arsonophenylazo)-1,8-dihydroxy-3,6-naphthalenedisulfonic Acid; NSC 91528; 2,2'-(1,8-Dihydroxy-3,6-disulfo-2,7-naphthylenebisazo)di-benzenearsonic Acid; 3,6-Bis[(o-arsonophenyl)azo]-4,5-dihydroxy-2,7-naphthalenedisulfonic Acid. Grades: Reagent Grade. CAS No. 1668-00-4. Pack Sizes: 1g, 5g. Molecular Formula: C??H??As?N?O??S?, Molecular Weight: 776.37. US Biological Life Sciences. | Worldwide |
| Arsenic(III) oxide, 99.95-100.05% ACS | Arsenic(III) oxide, 99.95-100.05% ACS. Group: Biochemicals. Grades: ACS Grade. CAS No. 1327-53-3. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| AS601245 | Cell-permeable. AS601245 is a potent, ATP-competitive JNK inhibitor (hJNK1: IC50=150nm, hJNK2: IC50=220nm and hJNK3: IC50=70nm). Displays anti-inflammatory properties and has been shown to reduce TNF-a plasma levels induced by LPS in mice. Group: Biochemicals. Alternative Names: (Z) -2- (Benzo[d]thiazol-2 (3H) -ylidene) -2- (2- ( (- (pyridine-3-yl) ethyl) amino) pyridine-4-yl) acetonitrile. Grades: Highly Purified. CAS No. 345987-15-7. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| ASB-16 (3- [N, N-Dimethyl (3-palmitoylaminopropyl) ammonio] propanesulfonate; Amidosulfobetaine-16) | A zwitterionic detergent useful for the solubilization of proteins including previously undetected membrane proteins. ASB-16 exhibits better protein solubilization properties than CHAPS. Also useful for solubilizing proteins for 2D-gel electrophoresis. Group: Biochemicals. Grades: Highly Purified. CAS No. 52562-29-5. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| Ascolactone ((3S,4R,6S)-3,4-Dihydroxy-6-undecyltetrahydro-2H-pyran-2-one) | Antifungal. Phytotoxic. Group: Biochemicals. Grades: Highly Purified. CAS No. 757995-43-0. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| Ascomycin (High Purity) (Immunomycin, FK520, Analog of FK-506, FR-900520, L-683590, NSC 106410, WS 7238A) | Macrolide antibiotic. Ethyl analog of FK506. Strong immunosuppressant. Binds to the FK-506-binding protein FKBP12. This complex inhibits calcineurin (protein phosphatase 2B (PP2B)). Suppresses the production of T helper type 1 (Th1) (interferon and IL-2) and Th2 (IL-4 and IL-10) cytokines in T lymphocytes and preferentially inhibits the activation of mast cells. Anti-inflammatory. Used for topical treatment of inflammatory skin diseases. Potently inhibits anti-IgE-induced histamine and cytokine release and reduces IgE-dependent p38 MAPK activation in human basophils. Inhibits basophil degranulation at the initial phase of allergic skin reactions. Antifungal. Antimalaria compound. Anticonvulsant (antiepileptic). Group: Biochemicals. Grades: Highly Purified. CAS No. 104987-12-4. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Ascorbic acid, 99-100.5% USP | Ascorbic acid, 99-100.5% USP. Group: Biochemicals. Grades: USP. Pack Sizes: 100g, 250g, 1Kg, 10Kg, 25Kg. US Biological Life Sciences. | Worldwide |
| ASIC Channel Modulator II, GMQ (2-guanidine-4-methylquinazoline, Acid-sensing Ion Channel Modulator II) | A positively charged guanidium-containing quinazoline that modulates ASIC function by blocking acid-induced maximal peak current as well as by altering ASICs pH dependence for activation and inactivation, enabling a partial, but sustained ASIC3 activation around neutral pH (4.4% of pH 5-induced peak current with 1mM GMQ at pH 7.4), which is inhibitable by Amiloride. Intraplantar paw injection (10ul 100uM) is reported to elicit a pain response in asic3+/+, but not asic3-/-, mice in vivo. GMQ targeting area appears to overlap with Amiloride binding site in the pore region, but is distinct from ASIC calcium binding site. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??N?. US Biological Life Sciences. | Worldwide |
| Asperlactone (5- (1-Hydroxyethyl) -3- (2, 3-epoxypropyl) butenolide; (R)-5-((S)-1-Hydroxyethyl)-3-((2S,3S)-3-methyloxiran-2-yl)furan-2(5H)-one) | Antibiotic. Nematicidal, insecticidal, antibacterial and antifungal. Group: Biochemicals. Grades: Highly Purified. CAS No. 76375-62-7. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Asperloxine A ((S)-4, 10-Dimethoxy-14, 15, 16, 16a-tetrahydro-benzo[e]oxepino[2', 3':4, 5]pyrimido[2, 1-c]pyrrolo[1, 2-a][1, 4]diazepine-6, 12-dione) | Natural benzodiazepine. Anti-inflammatory. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Aspinonene (6,7-Epoxy-5-hydroxymethyl-3-octen-2,5-diol, (2R,5S,E)-2-((2R,3S)-3-Methyloxiran-2-yl)hex-3-ene-1,2,5-triol) | Multifunctional fungal secondary metabolite. Related to aspyrone. Group: Biochemicals. Grades: Highly Purified. CAS No. 157676-96-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Aspirin-L-argininie | Aspirin-L-argininie. Group: Biochemicals. Grades: Highly Purified. CAS No. 37466-21-0. Pack Sizes: 500mg, 1000mg. Molecular Formula: C15H22N4O6, Molecular Weight: 354.36. US Biological Life Sciences. | Worldwide |
| Aspochalasin I | Cytotoxic. Melanogenesis inhibitor without cytotoxicity. Group: Biochemicals. Alternative Names: (3E, 5R, 6S, 9E, 10aS, 13S, 13aS, 14S, 16aR)-6, 7, 8, 10a, 13, 13a, 14, 15-Octahydro-5, 6-dihydroxy-9, 12, 13-trimethyl-14-(2-methylpropyl)-2H-oxacyclododecino[2, 3-d]isoindole-2, 16(5H)-dione. Grades: Highly Purified. CAS No. 670225-69-1. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H35NO5, Molecular Weight: ~417.5. US Biological Life Sciences. | Worldwide |
| Aspterric acid | Antibiotic. Pollen growth and development inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 67309-95-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Aspyrone ((5S,6R)-5-Hydroxy-6-methyl-3-((2S,3S)-3-methyl-oxiran-2-yl)-5,6-dihydro-2H-pyran-2-one) | Antibiotic. Shows nematicidal, insecticidal, antibacterial and antifungal activity. Related to asperlactone and aspinonene. Group: Biochemicals. Grades: Highly Purified. CAS No. 17398-00-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C9H12O4. US Biological Life Sciences. | Worldwide |
| AST-487 | Potent RET kinase inhibitor. AST 487 displays high selectivity and potency toward FLT3 as a molecular target, and which could potentially be used to override drug resistance in AML. Group: Biochemicals. Grades: Highly Purified. CAS No. 630124-46-8. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| (+/-)-Atenolol ( (±) -4- {2-Hydroxy-3- [ (1-methylethyl) amino] propoxy} benzeneacetamide, Beta1-Adrenergic Receptor Blocker, (±)-Atenolol, Beta1-Adrenergic Receptor Antagonist, (±)-Atenolol) | Selective beta-1 adrenergic blocking agent. An anti-hypertensive and anti-arrhythmic agent. Reported to diminish cerebrospinal fluid production. Group: Biochemicals. Grades: Highly Purified. CAS No. 29122-68-7. Pack Sizes: 1g. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| a-Tetralol 98+% (GC) | a-Tetralol 98+% (GC). Group: Biochemicals. Grades: GC. Pack Sizes: 1g, 5g, 25g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| ATIC Dimerization Inhibitor (Ac-Arg-Ph(4-NO2)-NEt2, ATIC Inhibitor, AICAR Tfase Inhibitor, AICAR Transformylase Inhibitor, AICAR Tranformylase/Inosine Monophosphate Cyclohydrolase Dimerization Inhibitor, AMPK Signaling Activator XI) | A cell-permeable dipeptide that reversibly blocks the homodimerization of aminoimidazole carboxamide ribonucleotide transformylase/inosine nomophosphate cyclohydrolase (ATIC) and inhibits its activity (Ki = 691nM, Kd = 240nM). AITC is a bifunctional enzyme that catalyzes the last two steps of de novo purine biosynthesis. Increases the intracellular levels of AICAR leading to the activation of AMP-activated protein kinase (AMPK). Shown to reduce cell viability in a dose-dependent manner. Exhibits a longer half-life and sustained AMPK activation (~24h), compared to AICA-riboside. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| (+)-a-Tocopherol sulfo-NHS succinate 99+% (NMR) | (+)-a-Tocopherol sulfo-NHS succinate 99+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| a-Tosyl-(2-bromobenzyl)isocyanide ≥97% (NMR) | a-Tosyl-(2-bromobenzyl)isocyanide ≥97% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| a-Tosyl- (4-chlorobenzyl) isocyanide ≥95% (HPLC) | a-Tosyl- (4-chlorobenzyl) isocyanide ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 918892-30-5. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| ATPA (2-Amino-3-(3-hydroxy-5-tert-bu-tylisoxazol-4-yl)propanoic Acid, (RS)-2-Amino-3-(3-hydroxy-5-tert-bu-tylisoxazol-4-yl)propanoic Acid, Kainate Receptor Agonist, ATPA, (R,S)-ATPA) | A potent agonist highly selective for GluK1-containing subtype kainate receptors (EC50 = 0.33, 0.80, and 0.38uM for GluK1, GluK1/K2, and GluK1/K5, respectively) over GluK2-containing subtypes (EC50 = 106 and ?uM for GluK2/K5 and GluK2 respectively). Weakly interacts with AMPA receptors (EC50 = 7.6, 7.9 and 22uM for GluA4, GluA3, and GluA1 respectively). Has been used in assessing the functional roles of GluK1-containing subtype kainate receptors in synaptic transmission and plasticity. Group: Biochemicals. Grades: Highly Purified. CAS No. 140158-50-5. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| Atpenin A5 (3-[(2S,4S,5R)-5,6-Dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1H)-pyridinone) | Synthetic. Originally isolated from Penicillium sp. strain. An antibiotic and antifungal agent. Potent and specific mitochondrial complex II (succinate-ubiquinone oxidoreductase) inhibitor and mitochondrial ATP-sensitive potassium (mK(ATP)) channel activator. Modulates mitochondrial ROS generation during cardioprotection. Group: Biochemicals. Grades: Highly Purified. CAS No. 119509-24-9. Pack Sizes: 250ug, 1mg. US Biological Life Sciences. | Worldwide |
| ATR/CDK Inhibitor, NU6027 (2,6-diamino-4-cyclohexyl-methyloxy-5-nitroso-pyrimidine, ATR Inhibitor, NU6027, CDK2 Inhibitor) | A cell-permeable, pyrimidine derivative that acts as an ATP-competitive CDK Inhibitor (Ki=2.5uM for CDK1, and Ki=1.3uM for CDK2), and demonstrates cytostatic properties among a panel of 57 cancer cell lines. Also inhibits ATR kinase (IC50=6.7uM in MCF7 cells), but does not interfere with irradiation-induced autophosphorylation of DNA-PK or ATM. Potentiates a range of DNA-damaging cytotoxic drugs such as hydroxyurea (1.8-fold) and cisplatin (1.4-fold) at 10uM, but not the anti-mitotic paclitaxel. Attenuates G2/M arrest following DNA damage and inhibits RAD51 focus formation. Shown to be synthetically lethal when DNA single-strand break repair is impaired in PARP-inhibited cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 220036-08-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| ATR Inhibitor IV (VE821, 3-amino-6- (4- (methylsulfonyl) phenyl) -N-phenylpyrazine-2-carboxamide, VE-821, ATM and Rad3-Related Inhibitor IV) | A cell-permeable phenylpyrazine derivative that acts as a potent, ATP-competitive (Ki= 13nM; IC50/[ATP] = 70nM/50uM and 128nM/100uM), ATR-selective inhibitor with much reduced or little potency against 4 related PIKKs (Ki= 2.2, 3.9, 16, and >1uM, respectively, against DNA-PK, PI 3-K-gamma, ATM, and mTOR) and 50 other kinases. Shown to selectively inhibit ATR-dependent H2AX Ser139 & Chk1 Ser345 phosphorylation (complete inhibition at 10uM in HT29 and HFL1 cultures) without affecting ATM- and DNA-PK-mediated H2AX or ATM-mediated Chk2 phosphorylation. Short-term (24h) VE-821 treatment, either alone or in synergy with Cisplatin, results in reversible cytostatic growth arrest regardless of cellular ATM-p53 pathway activity, while cytotoxicity and Cisplatin synergism in cell death induction is reported to occur only upon long-term VE-821 exposure (≥72h) in cultures with ATM-p53 pathway defects.CAS No.1232410-49-10. Group: Biochemicals. Grades: Highly Purified. CAS No. 1232410-49-10. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences. | Worldwide |
| ATR Kinase Inhibitor II (3-Amino-6-(4-((1-(dimethylamino)propan-2-yl)sulfonyl)-phenyl)-N-phenylpyrazine-2-carboxamide) | A cell-permeable aminopyrazinyl-sulfone compound that acts as a potent, reversible and ATP-competitive inhibitor of ATR kinase (IC50 = 12nM; Ki=6nM) with excellent selectivity over ATM, DNA-PK (IC50 > 8uM) and in a 50-kinase panel (% inhibition at 2uM = 59, 57, 55, 52, 43 and 42 for AMPK, Lck, RIPK2, Ret, IKK-alpha and FGFR3, respectively). Shown to block pH2AX-Ser139 (IC50 = 420nM in hydroxyurea treated HT29 cells) and preferentially enhance cisplatin cytotoxicity against tumor cells over normal cells by ~7-fold at 620nM. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences. | Worldwide |
| Auramine O Certified ≥95% (Dye content) | Auramine O Certified ≥95% (Dye content). Group: Biochemicals. Grades: Certified Dye. CAS No. 2465-27-2. Pack Sizes: 250g, 1Kg, 5Kg, 10Kg. US Biological Life Sciences. | Worldwide |
| Auranofin 99+% | Auranofin 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 25mg, 1g. US Biological Life Sciences. | Worldwide |
| Aurantimycin A | Depsipeptide antibiotic. Active against Gram-positive bacteria. Cytotoxic agent. Nematocide activity. Antiulcer agent. Anti-inflammatory drug (C5a antagonist). Group: Biochemicals. Grades: Highly Purified. CAS No. 162478-50-4. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Aureothin (Mycolutein, Distacin, JA 2814K, Antibiotic 74A, BRN 0058476) | Oxidoreductase inhibitor. Antitrypanosomal, antibacterial, antifungal, insecticidal and pesticidal. Antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 2825-00-5. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Aureothricin (Propionylpyrrothione, Farcinicin, N-(4-Methyl-5-oxo-4,5-dihydro-[1,2]dithiolo[4,3-b]pyrrol-6-yl)propionamide) | Antibiotic. Active against Gram-positive and Gram-negative bacteria, yeast, filamentous fungi, protozoa and insects. Potent bacterial and yeast RNA polymerases inhibitor. Inhibitor of fungal mannan and glucan formation. Similar to thiolutin. Antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 574-95-8. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| Aurodox (1-Methylmocimycin, Antibiotic X 5108, Goldinodox, Goldinomycin, NSC 233989) | Antibiotic. Protein biosynthesis inhibitor by binding to elongation factor Tu (EF-Tu). Type 3 secretion system (T3SS) inhibitor. Growth promotor in poultry. Group: Biochemicals. Grades: Highly Purified. CAS No. 12704-90-4. Pack Sizes: 1mg, 2.5mg. US Biological Life Sciences. | Worldwide |
| Aurodox (1-Methylmocimycin, Antibiotic X 5108, Goldinodox, Goldinomycin, NSC 233989, Benzamide, CYT11387) | Isolated from Streptomyces sp. K06-0806. Protein biosynthesis inhibitor by binding to elongation factor Tu (EF-Tu). Effective against streptococcus pyogenes infections. It may promote growth in poultry. Group: Biochemicals. Grades: Highly Purified. CAS No. 12704-90-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
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