Our biochemicals, antibodies, recombinant proteins, cell culture media and molecular biology kits are used in virtually all scientific applications.From affordable research quantities to larger bulk amounts.
b-Chloro-L-alanine methyl ester hydrochloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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BCRP Inhibitor III, YHO-13177 ((Z)-2-(3,4-Dimethoxyphenyl)-3-(5-(4-hydroxypiperidin-1-yl)thiophen-2-yl)acrylonitrile)
A cell-permeable acrylonitrile compound that potently inhibits breast cancer resistance protein (BCRP/ABCG2)-mediated drug export and reverses BCRP-mediated drug resistance in vitro (half maximal in the range 0.01-1uM) without altering the BCRP expression levels (in <6hrs.). Shown to selectively enable the intracellular accumulation of anticancer drugs and potentiate the cytotoxicity of BCRP-expressing carcinoma cells with no effect either on the P-glycoprotein/ABCB1- and MDRP1-mediated export or on the drug sensitivity of parental cells (IC50>10uM in A549 cells). An in vivo bioavailable and readily water soluble prodrug of YHO-13177, BCRP Inhibitor IV, YHO-13351 is also available. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
An in vivo bioavailable (~87%; t1/2 <5 mins. during p.o. and i.v. administration) and highly water soluble (>100mg/ml) diethylaminoacetate prodrug of YHO-13177 that reverses BCRP-mediated irinotecan resistance in P388/BCRP and HCT116/BCRP xenograft mouse models, and suppresses tumor growth and significantly enhances the survival (100 or 200mg/kg, i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
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b-Cyano-L-alanine 98+%
b-Cyano-L-alanine 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
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b-Cyclohexyl-D-alanine 99+%
b-Cyclohexyl-D-alanine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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b-Cyclohexyl-D-alaninehydrochloride
b-Cyclohexyl-D-alaninehydrochloride. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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b-Cyclohexyl-D-alanine methyl ester hydrochloride
b-Cyclohexyl-D-alanine methyl ester hydrochloride. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
b-Cyclohexyl-L-alanine 99+%
b-Cyclohexyl-L-alanine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences.
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b-Cyclohexyl-L-alanine amide 98+% (HPLC)
b-Cyclohexyl-L-alanine amide 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
b-Cyclohexyl-L-alanine hydrochloride 99+% (HPLC)
b-Cyclohexyl-L-alanine hydrochloride 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences.
Antibiotic. Semisynthetic H2O-soluble derivative of rebeccamycin. Antitumor compound. Topoisomerase II (Topo II) inhibitor. DNA intercalating agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 119673-08-4. Pack Sizes: 250ug, 1mg. US Biological Life Sciences.
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Beclin-1 Activator II, Retro-inverso TAT-Beclin-1 ((D)-H2N-RRRQRRKKRGY-GG-TGFEGDHWIEFTANFVNT-CO2H, Atg6 Activator II, Beclin-1-GAPR-1 Interaction Blocker II, Vps30 Activator II)
A cell-permeable, all-D-amino acid autophagy-inducing peptide based on the retro-inverso sequence of Tat-Beclin1 that is expected to be more resistant to proteolytic degradation than Tat-Beclin1 and is shown to be more potent than Tat-Beclin1 in inducing autophagy in muscle, heart, and pancreas tissues in 6-wk-old GFP-LC3 transgenic mice (20mg/kg i.p.) in vivo. Only the retro-inverso peptide, but not Tat-Beclin1, is effective in reducing autophagy substrate p26 level in the brain tissue of 5-d-old neontal GFP-LC3 mice (20mg/kg i.p.). The retro-inverso peptide treatment is also reported to greatly reduce brain viral titre in neonatal mice subjected to West Nile Virus infection. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C???H???N??O??. US Biological Life Sciences.
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Beclin-1 Activator I, TAT-Beclin-1 (Atg6 Activator I, Beclin1-GAPR-1 Interaction Blocker I, Vps30 Activator I, H2N-YGRKKRRQRRR-GG-TNVFNATFEIWHDGEFGT-CO2H)
A cell-permeable autophagy-inducing peptide (Effective conc. 30 to 100uM) that is designed based on the essential HIV-1 virulence factor Nef-binding sequence of atg6/beclin1 and N-terminally fused to the HIV-1 Tat protein transduction domain sequence. Tat-Beclin1 is reported to compete against Beclin1 for binding to its negative regulator GAPR-1/GLIPR2 on the Golgi surface. Shown to effectively induce autophagy-mediated clearance of small (<1uM) CFP-htt103Q aggregates in HeLa cells (20uM/4h/d for 2 d) and inhibit RNA viral replications both in cultures (4h 10uM peptide treatment 4h post CHIKV, SINV, or WNV infection in HeLa cultures; 24h 0.5-5uM peptide pre-treatment before HIV infection in human MDM cultures) in vitro and in mice (15-20mg/kg/day i.p.) in vivo. The in vivo bioavailability of Tat-Beclin1 is limited to the peripheral tissues in mice, while a peptide based on Tat-Beclin1 retro-inverso sequence is demonstrated to effectively target CNS. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C???H???N??O??, Sequence: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg~Gly-Gly~Thr-Asn-Val-Phe-Asn-Ala-Thr-Phe-Glu-Ile-Trp-His-Asp-Gly-Glu-Phe-Gly-Thr-OH. US Biological Life Sciences.
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Beloranib
Beloranib is a pharmaceutical drug that is currently being evaluated through biological studies for its potential to combat obesity. Group: Biochemicals. Grades: Highly Purified. CAS No. 251111-30-5. Pack Sizes: 250ug, 1mg. Molecular Formula: C29H41NO6. US Biological Life Sciences.
Poly(ADP-ribose) polymerase (PARP) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 117241-60-8. Pack Sizes: 500ug, 1mg. US Biological Life Sciences.
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Benserazide
Benserazide is a drug which in combination with dopamine precursor Levodopa (D533751) is used in the management of Parkinson’s disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 322-35-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C10H15N3O5, Molecular Weight: 257.24. US Biological Life Sciences.
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Benzaldehyde dimethyl acetal 98+% (GC)
Benzaldehyde dimethyl acetal 98+% (GC). Group: Biochemicals. Grades: GC. CAS No. 1125-88-8. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
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Benzamidine hydrochloride, anhydrous 99+%
Benzamidine hydrochloride, anhydrous 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 1670-14-0,477904-89-5. Pack Sizes: 5g, 25g. US Biological Life Sciences.
Worldwide
Benzamidine hydrochloride hydrate 99+%
Benzamidine hydrochloride hydrate 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
Benzenemethanesulfonyl chloride 98+%
Benzenemethanesulfonyl chloride 98+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 1939-99-7. Pack Sizes: 5g, 25g. US Biological Life Sciences.
Worldwide
Benzhydrylamine hydrochloride 98+%
Benzhydrylamine hydrochloride 98+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 5267-34-5. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
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Benzhydrylamine resin hydrochloride
Benzhydrylamine resin hydrochloride. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g. US Biological Life Sciences.
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Benzo[b]thiophene-7-carboxaldehyde ≥95% (HPLC)
Benzo[b]thiophene-7-carboxaldehyde ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Benzo[D]Thiazol-2-Yl(4-Methoxyphenyl)Methanol 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
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Benzofuran
Benzofuran is produced from coal tar. Found in tobacco smoke derived compounds, it is a carcinogen, seen to cause kidney damage. However it is also used in combination with phenolic antioxidants in meat curing. It has also recently been used in the synthesis of novel glutarimide antibiotics. Group: Biochemicals. Grades: Highly Purified. CAS No. 271-89-6. Pack Sizes: 5g, 25g. Molecular Formula: C8H6O. US Biological Life Sciences.
Benzyl ((2R,3R)-3-Hydroxy-1-(phenylthio)heptan-2-yl)carbamate is a derivative of N-Carbobenzyloxy-3-phenylthio-L-alanine (C176530) which is an intermediate in the synthesis of Nelfinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C21H27NO3S, Molecular Weight: 373.51. US Biological Life Sciences.