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Bis-maleimidomethylether 99+% (NMR)
Bis-maleimidomethylether 99+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg. US Biological Life Sciences.
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Bismark Brown R ≥98.5%
Bismark Brown R ≥98.5%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g. US Biological Life Sciences.
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Bismark Brown Y, Certified ≥45% (Dye content)
Bismark Brown Y, Certified ≥45% (Dye content). Group: Biochemicals. Grades: Certified Dye. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
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Bismuth(III) bromide 99+%
Bismuth(III) bromide 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 7787-58-8. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
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Bismuth(III) bromide 99+.9
Bismuth(III) bromide 99+.9. Group: Biochemicals. Grades: Reagent Grade. CAS No. 7787-58-8. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Bismuth(III) chloride 99+.95%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 7787-60-2. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
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Bismuth(III) nitrate pentahydrate 99+%
Bismuth(III) nitrate pentahydrate 99+%. Group: Biochemicals. Grades: Highly Purified. CAS No. 10035-06-0. Pack Sizes: 100g, 250g, 25g, 1Kg, 2.5Kg. US Biological Life Sciences.
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Bismuth nitrate pentahydrate ≥98.0% ACS
Bismuth nitrate pentahydrate ≥98.0% ACS. Group: Biochemicals. Grades: ACS Grade. CAS No. 10035-06-0. Pack Sizes: 100g, 1Kg, 5Kg, 10Kg. US Biological Life Sciences.
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Bisnonyl Dimethyl Ammonium Chloride
Bisnonyl Dimethyl Ammonium Chloride is a potential bactericide and algaecide. Also used in the engineering of a two-dimensional superlattice with photofunctional properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 23375-64-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C20H44ClN. US Biological Life Sciences.
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Bisphenol E
Bisphenol E is a derivative of Bisphenol A (B519495) which is a monomer used for polycarbonate and epoxy resins. Group: Biochemicals. Grades: Highly Purified. CAS No. 2081-8-5. Pack Sizes: 5mg, 10mg. Molecular Formula: C14H14O2. US Biological Life Sciences.
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Bisphenol Z-13C12
Bisphenol Z-13C12 is the isotope labelled analog of Bisphenol Z. Bisphenol Z is one of the many derivatives of Bisphenol A (B519495) that can be used as HIF (hypoxia-inducible factor) inhibitors, antitumor agents, angiogenesis inhibitors, and antihypoxic agents. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C613C12H20O2. US Biological Life Sciences.
A cell-permeable pyridinyl-thiadiazolylurea compound that selectively blocks Bloom's syndrome protein (BLM) helicase activity of both full-length as well as truncated BLM636-1298 forms (IC50 = 2.98 and 0.97uM, respectively). Competes with and reversibly blocks DNA binding to BLM. However, the inhibition appears to be non-competitive with respect to ATP. Exhibits anti-proliferative activity in cells expressing BLM, but not in those lacking BLM. Induces sister chromatid exchanges (SCEs) and enhances the sensitivity of BLM containing PSNF5 cells to aphidicolin without affecting PSNG13 cells that are devoid of BLM. Displays favorable microsomal (T1/2 > 1.2h) and plasma stability (~100% at 5h). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H?F?N?OS. US Biological Life Sciences.
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b-Maleimidopropionic acid hydrazide 99+%
b-Maleimidopropionic acid hydrazide 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg. US Biological Life Sciences.
A cell-permeable indandione compound that inhibits the Bmi1-Ring1A E3 complex ubiquitin ligase activity both in cell-free assays (by 100% against self- and Top2alpha ubiquitination at 25 and 50uM, respectively) and in HeLa cells (by 100% against Bmi1 ubiquitination at 50uM). Shown to greatly potentiate Teniposide (VM26) cancer cytotoxicity (by 10-fold in A375 and A549 cultures at 5.5 and 33uM, respectively) by preventing Top2alpha degradation following VM26 treatment (100% inhibition at 50uM in HeLa cells). Group: Biochemicals. Grades: Highly Purified. CAS No. 31083-55-3. Pack Sizes: 25mg. US Biological Life Sciences.
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BMP Inhibitor II, DMH1 (ALK2/3 Inhibitor, DMH1, Bone Morphogenetic Protein Inhibitor, DMH1, 4- (6- (4-Isopropoxyphenyl) pyrazolo[1, 5-a]pyrimidin-3-yl) quinoline)
A cell-permeable pyrrazolopyrimidine compound that inhibits against R/VEGFR2, ALK2/BMPR-I, AMPK kinase activity (IC50=25.1, 148, and 234.6nM, respectively), while exhibiting much reduced or little effect toward ALK5/TGFbR-I, ZAPK, Syk, PKCth, PKA, or JAK3. Shown to block both BMP pathway-dependent dorsoventral development (EC100=2.5uM) and VEGF signaling-dependent intersomitic vessel formation (EC50=5uM) in zebrafish embryo in vivo. Commonly used in combination with AMPK activators AICAR and/or Metformin for studying AMPK-dependent cellular events in vitro and physiological responses in animals in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 1206711-16-1. Pack Sizes: 5mg. US Biological Life Sciences.
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BMP Inhibitor III, LDN-212854 (Abl Inhibitor V, LDN212854, Bone Morphogenetic Protein Inhibitor III, PDGFR Tyrosine Kinase Inhibitor XXIV, RIP2 Inhibitor I, RIPK2 Inhibitor I, 5-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline)
A cell-permeable pyrazolopyrimidinyl quinoline that is superior to Dorsomorphin and DMH1 as an ATP-site-targeting, ALK1/2 inhibitor (IC50 = 2.40 and 1.30nM, respectively; [ATP] = 6uM) with respect to both potency and selectivity over ALK3/4/5 (IC50 = 0.858, 2.133, and 9.276uM, respectively). Also a potent RIPK2 inhibitor (IC50 = 6nM) with reduced potency against ABL1/c-abl, PDGFR-beta, ALK3, and PDGFR-alpha (IC50 = 40, 68, 85.8, and 650nM, respectively) and little inhibitory activity toward a panel of more than 190 kinases. Effectively inhibits ALK2- and ALK3-mediated C2C12 osteogenic differentiation (IC50 = 10 and 40.5nM, respectively) in vitro and prevents constitutively active ALK2 Q207D mutant-induced heterotopic ossification in mice (6mg/kg/12h via i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??N?. US Biological Life Sciences.
An orally bioavailable sulfonamide compound that acts as a potent, reversible and allosteric y-secretase activity inhibitor with ~15-fold greater selectivity over Notch-1 proteolysis processing (IC50=7.1 and 105.9nM in HEK293-wtAPP) and preferentially inhibits PS1 (presenillin 1)-comprised y-secretase (EC50=8, 108, 286 and 29nM for PS1, Triple PS1-L172M,T281P, L282I, PS2 and Triple PS2-M178L, P287T, I288L), respectively). Shown to reduce the levels of Ab38, Ab40 and Ab42 in Tg2576 mice, Ab40 brain and plasma in APP-YAC mice (ED50=30 and 16mg/kg, p.o.) and Abtotal brain, CSF and plasma in guinea pigs (ED50=30mg/kg, i.p.). Group: Biochemicals. Grades: Highly Purified. CAS No. 290315-45-6. Pack Sizes: 5mg. US Biological Life Sciences.
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BMX-IN-1
A cell-permeable tricyclic quinoline-acrylamide compound that potently inhibits BMX and BTK kinase activity (IC50 = 8 and 10.4nM, respectively) by covalently targeting ATP-binding site cysteine, while being less potent against TEC family kinases TEC, JAK3, BLK with the same conserved cysteine (IC50 = 175, 377, and 653nM, respectively). Only PI 3-K gamma/PIK3CG, SBK1, PIP5K2C (by ≥94% at 1uM), and TXK (by 75% at 1uM) are significantly inhibited by BMX-IN-1 in a selectivity profiling against 437 other kinase constructs. Potently inhibits the proliferation of TEL-BMX transformed Ba/F3 Ba/F3 (GI50 = 25nM), while being much less effective against TEL-BLK, TEL-JAK1, TEL-JAK2, TEL-JAK3, or TEL-TYK2E957D transformed Ba/F3 (GI50 = ≥3.64uM) or a panel of 5 prostate cancer cell lines (GI50 ≥2.46uM). Group: Biochemicals. Alternative Names: N- (2-Methyl-5- (9- (4- (methylsulfonamido) phenyl) -2-oxobenzo[h][1, 6]naphthyridin-1 (2H) -yl) phenyl) acrylamide, BMX/BTK Inhibitor, Bruton's Tyrosine Kinase Inhibitor IV, BLK Inhibitor I, BMX Inhibitor I, JAK3 Inhibitor XIII, PI 3-K Inhibitor XX, PIP5K2C Inhibitor I, SBK1 Inhibitor I, TEC Inhibitor I, TXK Inhibitor I. Grades: Highly Purified. CAS No. 1431525-23-4. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences.
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b-Naphthoflavone 99+%
b-Naphthoflavone 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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b-Naphthoxyacetic acid 98+%
b-Naphthoxyacetic acid 98+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 120-23-0. Pack Sizes: 100g, 1Kg, 5Kg, 10Kg. US Biological Life Sciences.
Worldwide
BNP, Positive Control (Natriuretic Peptides B, Gamma-brain Natriuretic Peptide, NPPB)
BNP, Positive Control (Natriuretic Peptides B, Gamma-brain Natriuretic Peptide, NPPB). Group: Molecular Biology. Pack Sizes: 15ul. US Biological Life Sciences.
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Boc-10-aminodecanoic acid 99+% (HPLC)
Boc-10-aminodecanoic acid 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 173606-50-3. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences.
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Boc-11-aminoundecanoic acid ≥95%
Boc-11-aminoundecanoic acid ≥95%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Boc-12-aminododecanoic acid
Boc-12-aminododecanoic acid. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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Boc-1,2-diaminoethane·HCl
Boc-1,2-diaminoethane·HCl. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences.
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Boc-1, 3-cis-diamino methyl cyclohexane·HCl 99+%
Boc-1, 3-cis-diamino methyl cyclohexane·HCl 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
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Boc-1,3-diaminopropane·HCl 99+%
Boc-1,3-diaminopropane·HCl 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 127346-48-9. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.