Alfa Chemistry is an ISO 9001:2015 Certified Supplier of various building blocks, reagents, catalysts, nanomaterials, reference materials, and research chemicals. In-stock products can be shipped quickly.
Dryocrassin ABBA (Dryocrassin) is an orally active flavonoid natural product derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities. Dryocrassin ABBA exhibits antiviral activity against H5N1 avian influenza virus. Dryocrassin ABBA inhibits the coagulase activity of Staphylococcus aureus vWbp. Dryocrassin ABBA suppresses immunostimulatory function of dendritic cells and prolongs skin allograft survival. Group: Inhibitors. CAS No. 12777-70-7. Molecular formula: C43H48O16. Mole weight: 820.81. Appearance: Yellow powder. Purity: 0.98. IUPACName: 2-acetyl-4-[[3-[[3-[(5-acetyl-2,6-dihydroxy-3,3-dimethyl-4-oxocyclohexa-1,5-dien-1-yl)methyl]-5-butanoyl-2,4,6-trihydroxyphenyl]methyl]-5-butanoyl-2,4,6-trihydroxyphenyl]methyl]-3,5-dihydroxy-6,6-dimethylcyclohexa-2,4-dien-1-one. Canonical SMILES: CCCC (=O)C1=C (C (=C (C (=C1O)CC2=C (C (C (=O)C (=C2O)C (=O)C) (C)C)O)O)CC3=C (C (=C (C (=C3O)C (=O)CCC)O)CC4=C (C (C (=O)C (=C4O)C (=O)C) (C)C)O)O)O. Catalog: ACM12777707.
DSPE-PEG(2000)-N-triphenylphosphonium
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[(polyethylene glycol)-2000]-N-[4- (triphenylphosphonium)butanamide]. Group: Peg lipids. CAS No. 2936622-20-5. Molecular formula: C154H282N2O55P2 (average MW due to polydispersity of PEG). Mole weight: 3103.86. Catalog: ACM2936622205.
DSPE-PEG-COOH
It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the acid group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide. Group: Functional pegs. Alternative Names: DSPE-PEG Carboxylic Acid. CAS No. 1403744-37-5. Appearance: Crystalline solid or semi-solid. Catalog: ACM1403744375.
DT-2216
DT2216 is a potent and selective Bcl-xL-specific degrader. DT2216 is highly active against Bcl-xL-dependent T cell lymphomas. DT2216 selectively killed various Bcl-xL-dependent TCL cells including MyLa cells in vitro. In vivo, DT2216 alone was highly effective against MyLa TCL xenografts in mice without causing significant thrombocytopenia or other toxicity. Furthermore, DT2216 combined with ABT199 (a selective Bcl-2 inhibitor) synergistically reduced disease burden and improved survival in a TCL PDX mouse model dependent on both Bcl-2 and Bcl-xL. Group: Others. Alternative Names: DT-2216; DT2216; DT 2216; DT2216 HCl. CAS No. 2365172-42-3. Molecular formula: C77H96ClF3N10O10S4. Mole weight: 1542.36. Appearance: Solid powder. Purity: >98%. IUPACName: (2S, 4R) -1- ( (S) -2- (7- (4- ( (R) -3- ( (4- (N- (4- (4- ( (4'-chloro-4, 4-dimethyl-3, 4, 5, 6-tetrahydro-[1, 1'-biphenyl]-2-yl) methyl) piperazin-1-yl) benzoyl) sulfamoyl) -2- ( (trifluoromethyl) sulfonyl) phenyl) amino) -4- (phenylthio) butyl) piperazin-1-yl) -7-oxoheptanamido) -3, 3-dimethylbutanoyl) -4-hydroxy-N- ( (S) -1- (4- (4-methylthiazol-5-yl) phenyl) ethyl) pyrrolidine-2-carboxamide. Canonical SMILES: CC1 (C) CCC (C2=CC=C (Cl) C=C2) =C (C1) CN3CCN (C4=CC=C (C (NS (=O) (C5=CC (S (C (F) (F) F) (=O) =O) =C (N[C@@H] (CSC6=CC=CC=C6) CCN7CCN (C (CCCCCC (N[C@@H] (C (C) (C) C) C (N8[C@@H] (C[C@@H] (O) C8) C (N[C@H] (C9=CC=C (C%10=C (N=CS%10) C) C=C9) C) =O) =O) =O) =O) CC7) C=C5)
DUN61488, also known as 2, 4, 6, 7, 8, 9-Hexahydro-7- (phenylmethyl) -4-[[4- (trifluoromethyl) phenyl]methyl]imidazo[1, 2-a]pyrido[3, 4-e]pyrimidin-5 (1H) -one is a chemical reagent for research use. Group: Others. Alternative Names: DUN61488; DUN-61488; DUN 61488. CAS No. 1807861-48-8. Molecular formula: C24H23F3N4O. Mole weight: 440.47. Appearance: Solid powder. Purity: >98%. IUPACName: 2, 4, 6, 7, 8, 9-Hexahydro-7- (phenylmethyl) -4-[[4- (trifluoromethyl) phenyl]methyl]imidazo[1, 2-a]pyrido[3, 4-e]pyrimidin-5 (1H) -one. Canonical SMILES: O=C1N (CC2=CC=C (C (F) (F)F)C=C2)C3=NCCN3C4=C1CN (CC5=CC=CC=C5)CC4. Catalog: ACM1807861488.
DUN99845
DUN99845 is a a lifespan-altering agent. DUN99845 was first reported in patent US 20090163545. DUN99845 was also reported as a STING inhbiitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING-mediated disease. Group: Inhibitors. Alternative Names: DUN99845; DUN-99845; DUN 99845. CAS No. 727699-84-5. Molecular formula: C26H21FN2O4S. Mole weight: 476.52. Appearance: Solid powder. Purity: >98%. IUPACName: N-[3-[[(4-Fluorophenyl)sulfonyl]amino]-4-methoxyphenyl][1,1'-biphenyl]-4-carboxamide. Canonical SMILES: O=C (C1=CC=C (C2=CC=CC=C2)C=C1)NC3=CC=C (OC)C (NS (=O) (C4=CC=C (F)C=C4)=O)=C3. Catalog: ACM727699845.
Dunaliella Salina Micro-Algae Extract
Highly purified extract from the microalgae Dunaliella salina consisting of a powerful blend of active substances including amino acids and carbohydrates. Visibly energizes and rejuvenates skin. Has effective moisturizing and skin-conditioning properties. Uses: Anti-aging, rejuvenating, revitalizing skin care products. Group: Skin actives. CAS No. 7732-18-5 / 9004-78-8 / 532-32-1 / 24634-61-5. Appearance: Pale-yellow liquid. Catalog: CI-SC-1043.
Dup-721
Dup-721 is a new antimicrobial agent belonging to the oxazolidinone series, a new class of synthetic antibacterial agents. Group: Others. Alternative Names: Dup-721; Dup721; Dup 721. CAS No. 104421-21-8. Molecular formula: C14H16N2O4. Mole weight: 276.29. Appearance: Solid powder. Purity: >98%. IUPACName: (S)-N-((3-(4-acetylphenyl)-2-oxooxazolidin-5-yl)methyl)acetamide. Canonical SMILES: CC (C1=CC=C (N2C[C@H] (CNC (C)=O)OC2=O)C=C1)=O. Catalog: ACM104421218.
Dyclonine (Dyclocaine) hydrochloride is an orally effective ALDH covalent inhibitor (crosses blood-brain barrier), with an IC50 of 35 μM for ALDH2 and 76 μM for ALDH3A1. Dyclonine hydrochloride has sensitizing activities for targeted cancer cells and antibacterial. Dyclonine hydrochloride is also a local anesthetic that blocks the transmission of various nerve impulses or stimuli and inhibits the sensation of touch and pain. Group: Inhibitors. Alternative Names: DYCLONINE;DYCLONINE HCL;DYCLONINE HYDROCHLORIDE;LABOTEST-BB LT00771942;1-(4-BUTOXYPHENYL)-3-(1-PIPERIDINYL)-1-PROPANONE HCL;1-(4-BUTOXYPHENYL)-3-(1-PIPERIDINYL)-1-PROPANONE hydROCHLORide ; 1- (4-butoxyphenyl) -3- (1-piperidinyl) -1-propanon hydrochloride ; 4'-butoxy-3-piperidinopropiophenone hydrochloride. CAS No. 536-43-6. Molecular formula: C18H28ClNO2. Mole weight: 325.87. Appearance: White Crystalline Solid. Purity: 0.96. IUPACName: dyclonine hydrochloride. Catalog: ACM536436.
Dynamin inhibitory peptide
Dynamin inhibitory peptide competitively blocks binding of dynamin to amphiphysin, thus preventing endocytosis. Dynamin inhibitory peptide blocks the dopamine D3 effect on GABAA receptors. Group: Inhibitors. Alternative Names: DYNAMIN INHIBITORY PEPTIDE;P4. CAS No. 251634-21-6. Molecular formula: C61H107N19O14. Mole weight: 1121.25. Appearance: Solid. Purity: 0.9617. Catalog: ACM251634216.
Dysprosium Acetate 99.9%
Heterocyclic Organic Compound. CAS No. 115280-55-4. Purity: 0.96. Catalog: ACM115280554.
Dysprosium Arsenide
Dysprosium Arsenide is a crystalline solid used as a semiconductor and in photo optic applications. An arsenide, an anion with the charge -3, is a rare mineral group consisting of compounds of one or more metals with arsenic (As). Arsenide anions have no existence in solution since they are extremely basic. These solid salts have very hHigh lattice energies and are toxic due to the inherent toxicity of arsenic. Group: Heterocyclic organic compound. Alternative Names: DYSPROSIUM ANTIMONIDE;DYSPROSIUM ARSENIDE;Dysprosium arsenide (dyas);Einecs 234-473-1. CAS No. 12005-81-1. Molecular formula: DyAs. Mole weight: 237g/mol. Appearance: Crystalline. Catalog: ACM12005811.
Dysprosium Carbide
Dysprosium Carbide is available in numerous forms and custom shapes including Ingot, foil, rod, plate and sputtering target. Group: Dy. CAS No. 12175-80-3. Molecular formula: DyC2. Appearance: solid. Catalog: ACM12175803.
Dysprosium Hydroxide
Dysprosium is one of the components of Terfenol-D,which is employed in transducers, wide-band mechanical resonators, and hHigh-precision liquid-fuel injectors. Dysprosium and its compounds are hHighly susceptible to magnetization, they are employed in various data-storage applications, such as in hard disks. Uses: Dysprosium hydrate, has specialized uses in ceramics, glass, phosphors, lasers and dysprosium metal halide lamp. high purity of dysprosium hydroxide is used in electronics industry as an antireflection coating in photoelectric devices. Group: Heterocyclic organic compound. CAS No. 1308-85-6. Molecular formula: Dy(OH)3.xH2O. Mole weight: 214g/mol. Appearance: White. Catalog: ACM1308856.
Dysprosium(II) Bromide
Dysprosium Bromide is a hHighly water soluble crystalline Dysprosium source for uses compatible with Bromides and lower (acidic) pH. Group: Dy. CAS No. 83229-05-4. Molecular formula: DyBr2. Mole weight: 322g/mol. Appearance: Black Crystalline Solid. Catalog: ACM83229054.
Dysprosium(III) acetate hydrate
Dysprosium(III) Acetate Hydrate is a moderately water soluble crystalline Dysprosium source that decomposes to Dysprosium oxide on heating. It is generally immediately available in most volumes. All metallic acetates are inorganic salts containing a metal cation and the acetate anion, a univalent (-1 charge) polyatomic ion composed of two carbon atoms ionically bound to three hydrogen and two oxygen atoms (Symbol: CH3COO) for a total formula weHight of 59.05. Group: Micro/nanoelectronics. Alternative Names: Acetic acid;dysprosium;hydrate. CAS No. 304675-49-8. Molecular formula: C6H14DyO7. Mole weight: 360.67. Appearance: Powder. Purity: 0.99. IUPACName: dysprosium(3+);triacetate;hydrate. Canonical SMILES: CC(=O)O.CC(=O)O.CC(=O)O.O.[Dy]. Catalog: ACM304675498-1.
Dysprosium(III) Bromide
Dysprosium Bromide is a hHighly water soluble crystalline Dysprosium source for uses compatible with Bromides and lower (acidic) pH. Group: Metal & ceramic materials. Alternative Names: CTK3J1628; Dysprosium bromide; dysprosium(3+) tribromide; RT-004985; 14456-48-5; Dysprosium tribromide; AC1L37HV. CAS No. 14456-48-5. Molecular formula: DyBr3. Mole weight: 402g/mol. Appearance: White Powder. IUPACName: dysprosium(3+);tribromide. Canonical SMILES: [Br-].[Br-].[Br-].[Dy+3]. ECNumber: 238-443-9. Catalog: ACM14456485.
Dysprosium(II) Iodide
Dysprosium Iodide is insoluble in water, and is often used in the synthesis of fine chemicals, and as a heat and lHight stabilzer for nylon fabrics. Dysprosium Iodide is generally immediately available in most volumes. HHigh purity, submicron and nanopowder forms may be considered. Iodide compounds are used in internal medicine. Treating an iodide with manganese dioxide and sulfuric acid sublimes the iodine. Group: Metal & ceramic materials. Alternative Names: Dysprosium iodide(DyI2) (9CI); 36377-94-3; CTK4H6371; DTXSID20849397; PUBCHEM_71431174; KS-000018LZ. CAS No. 36377-94-3. Molecular formula: DyI2. Mole weight: 416g/mol. Appearance: powder. IUPACName: dysprosium;diiodide. Canonical SMILES: [I-].[I-].[Dy]. Catalog: ACM36377943.
Dysprosium(III) oxide
DryPowder. Uses: Dierbium trioxide also called erbia, an important colourant in glasses and porcelain enamel glazes. high purity dierbium trioxide are widely applied as dopant in making optical fibre and amplifier. it is particularly useful as an amplifier for fiber optic data transfer. dierbium trioxide has a pink color, and is sometimes used as a colorant for glass, cubic zirconia and porcelain. the glass is then often used in sunglasses and cheap jewelry. Group: Nanoparticles & nanopowders. Alternative Names: Dysprosium sesquioxide. CAS No. 1308-87-8. Molecular formula: Dy2O3;Dy2O3. Mole weight: 373g/mol. Appearance: White. Purity: 99%, 99.9%, 99.99%, 99.999%. IUPACName: dysprosium(3+);oxygen(2-). Canonical SMILES: [O-2].[O-2].[O-2].[Dy+3].[Dy+3]. Density: 7.81 g/cm³. ECNumber: 215-164-0. Catalog: ACM1308878.
Dysprosium Phosphate
Dysprosium Phosphate is generally immediately available in most volumes. HHigh purity, submicron and nanopowder forms may be considered. Group: Heterocyclic organic compound. Alternative Names: Dysprosium phosphate, EINECS 237-605-6, 13863-49-5. CAS No. 13863-49-5. Molecular formula: DyPO4. Mole weight: 257g/mol. Appearance: Powder. Purity: 0.96. IUPACName: dysprosium(3+) phosphate. Catalog: ACM13863495.
Dysprosium Sulfide
Dysprosium Sulfide is a moderately water and acid soluble Dysprosium source for uses compatible with sulfates. Sulfate compounds are salts or esters of sulfuric acid formed by replacing one or both of the hydrogens with a metal. Most metal sulfate compounds are readily soluble in water for uses such as water treatment, unlike fluorides and oxides which tend to be insoluble. Group: Heterocyclic organic compound. Alternative Names: DYSPROSIUM SULFIDE;DYSPROSIUM SULFIDE 99.9%. CAS No. 12133-06-1. Molecular formula: DyS. Mole weight: 195g/mol. Appearance: Powder. Catalog: ACM12133061.
Dysprosium Telluride
Dysprosium Telluride (Dy2Te3) is a crystal grown product generally immediately available in most volumes. Technical, research and safety (MSDS) information is available as is a Reference Calculator for converting relevant units of measurement. Dysprosium Telluride (DyTe) is also available as quantum dots. DyTe Quantum Dots have the widest wavelength range reaching sizes as small as less then 500 nm; within the range sufficient to emit lHight in the blue-white range. Dysprosium Telluride Quantum Dots are charged aqueous soluble nano crystals with narrow emission spectra from 490 nm to 740 nm. Dysprosium Telluride (DyTe) is also used in solar energy and advanced optical applications. Group: Heterocyclic organic compound. Alternative Names: DYSPROSIUM TELLURIDE;didysprosium tritelluride. CAS No. 12159-43-2. Molecular formula: Dy2Te3. Mole weight: 708g/mol. Appearance: Black powder. Catalog: ACM12159432.
(E)-1, 1'-[Vinylenebis(sulfonyl)]bispropane
Heterocyclic Organic Compound. Alternative Names: Preseed, Vancide PA, Vancide PA dispersion, Caswell No. 099, Chemagro B 1843, Chemagro B-1843, Chemagro B1843, CHE 1843, 1,2-Bis(propylsulfonyl)ethylene, EINECS 214-200-2, trans-1,2-Bis(propylsulfonyl)ethene, NSC 68091, trans-1,2-Bis(n-propylsulfonyl)ethylene, (E)-1,2-Bis(propylsulfonyl)ethylene, AIDS125315, EPA Pesticide Chemical Code 011701, trans-1,2-Bis(propylsulfonyl)ethylene, AIDS-125315, NSC68091, trans-1, 2-Bis(propylsulfonyl)ethene. CAS No. 1113-14-0. Molecular formula: C8H16O4S2. Mole weight: 240.340240 [g/mol]. Purity: 0.96. IUPACName: 1-[ (E) -2-propylsulfonylethenyl]sulfonylpropan e. Density: 1.224g/cm³. Catalog: ACM1113140.
Alfa Chemistry offers (E)-1,2-Bis(2-naphthyl)-1,2-bis(1,1,3,3,5,5,7,7-octaethyl-1,2,3,5,6,7-hexahydro-s-indacen-4-yl)disilene products for various research purposes. Please contact us by email if you do not find the specification you are looking for on this page. Uses: Functional dyes for photonics and optics. Group: Other materials. Alternative Names: (Eind)(2-Naph)Si=Si(2-Naph)(Eind). CAS No. 1253900-41-2. Molecular formula: C76H104Si2. Mole weight: 1073.84. Appearance: Light yellow to Yellow to Orange powder to crystal. Purity: >97.0%(HPLC). IUPACName: (E)-naphthalen-2-yl-[naphthalen-2-yl-(1,1,3,3,5,5,7,7-octaethyl-2,6-dihydro-s-indacen-4-yl)silylidene]-(1,1,3,3,5,5,7,7-octaethyl-2,6-dihydro-s-indacen-4-yl)silane. Canonical SMILES: CCC1 (CC (C2=C (C3=C (C=C21)C (CC3 (CC)CC) (CC)CC)[Si] (=[Si] (C4=CC5=CC=CC=C5C=C4)C6=C7C (=CC8=C6C (CC8 (CC)CC) (CC)CC)C (CC7 (CC)CC) (CC)CC)C9=CC1=CC=CC=C1C=C9) (CC)CC)CC. Catalog: ACM1253900412.
E3330
E3330 (APX-3330) is a direct, orally active and selective inhibitor of Ape-1 (apurinic/apyrimidinic endonuclease 1)/Ref-1 (redox factor-1) redox. E3330 is able to impair tumor growth and blocks the activity of NF-κB, AP-1, and HIF-1α in pancreatic cancer. E3330 shows anticancer activities. Group: Inhibitors. CAS No. 136164-66-4. Molecular formula: C21H30O6. Mole weight: 378.46. Appearance: Solid. Purity: 0.9934. Canonical SMILES: CCCCCCCCC/C (C (O)=O)=C\C1=C (C)C (C (OC)=C (OC)C1=O)=O. Catalog: ACM136164664.
Heterocyclic Organic Compound. CAS No. 1138566-90-1. Catalog: ACM1138566901.
E6446
E6446 is a TLR inhibitor. E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro. When administered to mice, this compound suppress responses to challenge doses of cytidine-phosphate-guanidine (CpG)-containing DNA, which stimulates TLR9. Group: Inhibitors. Alternative Names: E6446; E 6446; E-6446. CAS No. 1219925-73-1. Molecular formula: C27H35N3O3. Mole weight: 449.6. Appearance: Solid powder. Purity: >98%. IUPACName: 6-(3-Pyrrolidin-1-yl-propoxy)-2-[4-(3-pyrrolidin-1-yl-propoxy)-phenyl]-benzooxazole. Canonical SMILES: C1 (C2=CC=C (OCCCN3CCCC3)C=C2)=NC4=CC=C (OCCCN5CCCC5)C=C4O1. Catalog: ACM1219925731.
Ebselen
Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker. Ebselen potently inhibits Mpro (IC50=0.67 μM) and COVID-19 virus (EC50=4.67 μM).Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity. Group: Inhibitors. Alternative Names: 2-phenyl-2-benzisoselenazol-3(2h)-one;PZ51;2-phenyl-benzo[d]isoselenazol-3-one;2-PHENYL-1,2-BENZISOSELENAZOL-3(2H)-ONE;EBSELEN;EBSELEN (PZ51, 2-PHENYL-1,2-BENZISOSELEN AZOL-3(2H)-ONE);EBSELEN 99%;2-phenyl-1,2-benzisoselenazol-. CAS No. 60940-34-3. Molecular formula: C13H9NOSe. Mole weight: 274.18. Appearance: light yellow solid. Purity: 0.96. IUPACName: 2-phenyl-1,2-benzoselenazol-3-one. Canonical SMILES: C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2. ECNumber: 612-054-8. Catalog: ACM60940343.
(-)-Eburnamonine is a natural product that is obtained from the roots of Eucalyptus globulus. It is an inhibitor of sodium citrate, which is used in the treatment of infectious diseases. (-)-Eburnamonine has been shown to be effective against intestinal inflammation and bowel disease by reducing the production of inflammatory cytokines. The molecule also inhibits hydroxyl group formation and has been shown to have minimal toxicity in animal studies. It also affects brain functions, such as energy metabolism, and may have significant cytotoxicity against cancer cells. Group: Other alkaloids. CAS No. 4880-88-0. Molecular formula: C19H22N2O. Mole weight: 294.39 g/mol. Canonical SMILES: CC[C@@]12CCCN3[C@@H]1C4=C (CC3)C5=CC=CC=C5N4C (=O)C2. Catalog: ACM4880880.
Ecdysone 25-O-glucopyranoside
Heterocyclic Organic Compound. CAS No. 112172-82-4. Catalog: ACM112172824.
Isoquinoline Alkaloids. Alternative Names: Trabectedin intermediates N-1. CAS No. 114899-80-8. Mole weight: 770.8. Purity: 95%+. Catalog: ACM114899808.
Ectoine
4-pyrimidincarbonsure (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a natural compound found in several species of bacteria. It is a compatible solute which serves as a protective substance by acting as an osmolyte and thus helps organisms survive extreme osmotic stress. 4-pyrimidincarbonsure is found in high concentrations in halophilic microorganisms and confers resistance towards salt and temperature stress. 4-pyrimidincarbonsure was first identified in the microorganism Ectothiorhodospira halochloris, but has since been found in a wide range of Gram-negative and Gram-positive bacteria. Other species of 4-pyrimidincarbonsure were found in. Group: Heterocyclic organic compound. Alternative Names: (S)-1,4,5,6-Tetrahydro-2-methyl-4-pyrimidincarbonsure. CAS No. 96702-03-3. Molecular formula: C6H10N2O2. Mole weight: 142.16. Appearance: White powder. Purity: 0.98. IUPACName: (6S)-2-methyl-1,4,5,6-tetrahydropyrimidine-6-carboxylic acid. Canonical SMILES: CC1=NCC[C@H](N1)C(=O)O. Density: 1.37 g/ml. Catalog: ACM96702033.
Edelweiss Extract
High-purity extract from the Swiss alpine flower Edelweiss (leontopodium alpinum). For natural and/or organic products. Active ingredients: bisabolane, sitosterol, tannin, chlorogenic acid, apigenin-7-glucoside, luteolin, luteolin-4-glucoside. Dissolved in water and glycerin. Uses: Anti-aging & anti-wrinkle products, pre/after sun lotions, hydrating and antioxidant skin care products, eye wrinkle products. Group: Skin actives. CAS No. 56-81-5 / 7732-18-5 / 391900-47-3 / 24634-61-5 / 532-32-1. Appearance: Clear dark brown liquid, faint plant odor. Catalog: CI-SC-0658.
Edratide
Edratide (TV 4710) is a synthetic peptide of 19 amino acid based on the complementarity-determining region 1 (CDR1) of a human anti-DNA antibody that expresses a major idiotype denoted 16/6 Id. Edratide reduces the rates of apoptosis (Apoptosis) and down-regulates of caspase-8 and caspase-3, up-regulates Bcl-xL. Edratide has the potential for the research of systemic lupus erythematosus (SLE). Group: Inhibitors. Alternative Names: Edratide;Edratide [inn];Glycyl-L-tyrosyl-L-tyrosyl-L-tryptophyl-L-seryl-L-tryptophyl-L-isoleucyl-L-arginyl-L-glutaminyl-L-prolyl-L-prolylglycyl-L-lysylglycyl-L-glutamyl-L-glutamyl-L-tryptophyl-L-isoleucylglycine;Unii-38plp07bkc. CAS No. 433922-67-9. Molecular formula: C111H149N27O28. Mole weight: 2309.56. Appearance: Solid. Purity: 0.9864. Catalog: ACM433922679.
Efinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). Efinaconazole acts as a 14α-demethylase inhibitor. Efinaconazole inhibits fungal lanosterol 14α-demethylase involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. Efinaconazole has been shown to be active against isolates of the following microorganisms, both in vitro and in clinical infections. Efinaconazole exhibits in vitro minimum inhibitory concentrations (MICs) of 0.06 μg/mL or less against most ( ≥ 90%) isolates of the following microorganisms: Trichophyton rubrum; Trichophyton mentagrophytes. Group: Inhibitors. Alternative Names: KP103; KP-103; KP 103; CTK5J2975; AGJ95634; KB145948; Efinaconazole; trade name: Jublia. CAS No. 164650-44-6. Molecular formula: C18H22F2N4O. Mole weight: 348.39. Appearance: Solid powder. Purity: >98%. IUPACName: (2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol. Canonical SMILES: C[C@@H] (N1CCC (CC1)=C)[C@@] (O) (C2=CC=C (F)C=C2F)CN3N=CN=C3. Catalog: ACM164650446.
≥99% (HPLC). Uses: Eh44 is a li+ free, hydrophobic hole transporting material (htm). it eliminates degradation due to li+ migration, supresses degradation due to moisture absorption and thus showed promise for achieving long-term stability in fabricated perovskite solar cells. using eh44 as htm in a device configuration of: sno2/pal/eh44/moox /al, not only generated high power conversion efficiency (pce) comparable. Group: Perovskite materials. Alternative Names: 9-(2-Ethylhexyl)-N,N,N,N-tetrakis(4-methoxyphenyl)- 9H-carbazole-2,7-diamine). CAS No. 1879076-81-9. Molecular formula: CuSCN. Mole weight: 733.94 g/mol. Appearance: powder. Purity: ≥99%HPLC. Canonical SMILES: CCC (CCCC)CN1C2=CC (N (C3=CC=C (OC)C=C3)C4=CC=C (OC)C=C4)=CC=C2C5=CC=C (N (C6=CC=C (OC)C=C6)C7=CC=C (OC)C=C7)C=C15. Catalog: ACM1879076819-1.
EH-IDTBR
Band gap: 1.68 eV. Group: N-type small molecules. CAS No. 2102510-60-9. Mole weight: 1326.03. Catalog: ACM2102510609.
Elacestrant , also known as RAD1901, is an orally available, selective estrogen receptor degrader (SERD) and selective estrogen receptor modulator (SERM), with potential antineoplastic and estrogen-like activities. Upon oral administration of higher doses of RAD1901, this agent acts as a SERD, which binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This may inhibit the growth and survival of ER-expressing cancer cells. At lower doses of this agent, RAD1901 acts as a SERM and has estrogen-like effects in certain tissues, which can both reduce hot flashes and protect against bone loss. In addition, RAD1901 is able to cross the blood-brain barrier (BBB). Group: Others. Alternative Names: RAD1901; RAD-1901; RAD 1901; RAD1901 HCl salt; Elacestrant dihydrochloride; Elacestrant HCl. CAS No. 1349723-93-8. Molecular formula: C30H40Cl2N2O2. Mole weight: 531.56. Appearance: Solid powder. Purity: >98%. IUPACName: (R)-6- (2- (ethyl (4- (2- (ethylamino)ethyl)benzyl)amino)-4-methoxyphenyl)-5, 6, 7, 8-tetrahydronaphthalen-2-ol dihydrochloride. Canonical SMILES: OC1=CC=C2C[C@H] (C3=CC=C (OC)C=C3N (CC4=CC=C (CCNCC)C=C4)CC)CCC2=C1. [H]Cl. [H]Cl. Catalog: ACM1349723938.
Elderberry Extract
Extract obtained from Sambucus Nigra (Elderberry) fruits. Contains 20% extract dissolved in water and glycerin. Soothing, moisturizing and calming properties. Useful for anti-irritant creams and lotions. Uses: Creams, lotions, masks. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 84603-58-7 / 122-99-6. Appearance: Medium to dark amber liquid, characteristic odor. Catalog: CI-SC-0830.
Elderberry Flower Extract
Extract obtained from Sambucus Nigra (Elderberry) flowers. Natural toning solution for skin tightness. Acts through in-vitro proven reduction of VEGF biosynthesis. Clear to slightly opalescent, yellow to brown colored, slightly viscous liquid with characteristic odor. Has natural toning and skin-tightening properties for skin fitness. Uses: Any kind of skin lotions, facial toners and toning solutions. Group: Skin actives. CAS No. 84603-58-7 / 56-81-5 / 7732-18-5 / 77-92-9 / 532-32-1 / 24634-61-5. Catalog: CI-SC-0992.
Eleclazine HCl
Eleclazine HCl is a novel late Na+ current inhibitor. Group: Inhibitors. Alternative Names: Eleclazine Hydrochloride; Eleclazine HCl; GS-6615; GS 6615; GS6615. CAS No. 1448754-43-5. Molecular formula: C21H17ClF3N3O3. Mole weight: 451.83. Appearance: Solid powder. Purity: >98%. IUPACName: 4-(pyrimidin-2-ylmethyl)-7-(4-(trifluoromethoxy)phenyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one hydrochloride. Canonical SMILES: O=C1N (CC2=NC=CC=N2)CCOC3=CC=C (C4=CC=C (OC (F) (F)F)C=C4)C=C13. [H]Cl. Catalog: ACM1448754435.
Elemicin
Elemicin is a alkenylbenzene widely distributed in many herbs and spices. Elemicin inhibits Stearoyl-CoA Desaturase 1 (SCD1) by metabolic activation. Elemicin is one of the main components in aromatic food and has antimicrobial, antioxidant, and antiviral activities. Elemicin possesses genotoxicity and carcinogenicity. Group: Inhibitors. Alternative Names: 1,2,3-TRIMETHOXY-5-(2-PROPENYL)BENZENE;5-ALLYL-1,2,3-TRIMETHOXYBENZENE;ELEMICIN;1,2,3-trimethoxy-5-(2-propenyl)-benzen;1,2,3-trimethoxy-5-allylbenzene (elemicin);3,4,5-Trimethoxyallylbenzene;4-allyl-1,2,6-trimethoxybenzene;5-allyl-1,2,3-trimethoxy-benzen. CAS No. 487-11-6. Molecular formula: C12H16O3. Mole weight: 208.3. Appearance: Oil. Purity: 0.98. IUPACName: 1,2,3-trimethoxy-5-prop-2-enylbenzene. Canonical SMILES: COC1=CC(=CC(=C1OC)OC)CC=C. Density: 1.011 g/cm³. Catalog: ACM487116.
Eleutherobin can be isolated from a marine soft coral. Group: Inhibitors. Alternative Names: β-D-Arabinopyranoside, [(4R,4aS,5Z,7R,10S,11S,12aR)-3,4,4a,7,10,11,12,12a-octahydro-7-methoxy-1,10-dimethyl-4-(1-methylethyl)-11-[[(2E)-3-(1-methyl-1H-imidazol-4-yl)-1-oxo-2-propen-1-yl]oxy]-7,10-epoxybenzocyclodecen-6-yl]methyl, 2-acetate. CAS No. 174545-76-7. Molecular formula: C35H48N2O10. Mole weight: 656.8. Purity: 95%+. IUPACName: [(1S,2S,4R,8R,9S,10Z,12R)-11-[[(2R,3S,4R,5R)-3-Acetyloxy-4,5-dihydroxyoxan-2-yl]oxymethyl]-12-methoxy-1,5-dimethyl-8-propan-2-yl-15-oxatricyclo[10.2.1.04,9]pentadeca-5,10,13-trien-2-yl] (E)-3-(1-methylimidazol-4-yl)prop-2-enoate. Canonical SMILES: CO[C@@]12/C (CO[C@H]3[C@H] ([C@@H] ([C@@H] (CO3)O)O)OC (C)=O)=C\[C@@]4 ([H])[C@@] (C (C)=CC[C@@H]4C (C)C) ([H])C[C@@H] ([C@@] (O1) (C=C2)C)OC (/C=C/C5=CN (C)C=N5)=O. Catalog: ACM174545767.
Eleutheroside B1
Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 μg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities. Group: Inhibitors. CAS No. 16845-16-2. Molecular formula: C17H20O10. Mole weight: 384.33. Appearance: Solid. Purity: 0.98. Canonical SMILES: O=C1C=CC2=CC (OC)=C (O[C@@H]3[C@@H] ([C@H] ([C@@H] ([C@@H] (CO)O3)O)O)O)C (OC)=C2O1. Catalog: ACM16845162.
Elimusertib free base
Elimusertib, also known as BAY-1895344, is a potent and selective ATM inhibitor. BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride. Group: Inhibitors. Alternative Names: Elimusertib, free base; BAY-1895344; BAY 1895344; BAY1895344. CAS No. 1876467-74-1. Molecular formula: C20H21N7O. Mole weight: 375.44. Appearance: Solid powder. Purity: >98%. IUPACName: (R)-3-methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine. Canonical SMILES: CN1N=CC=C1C2=CC (N3[C@H] (C)COCC3)=NC4=C (C5=CC=NN5)N=CC=C24. Catalog: ACM1876467741.
Ellipticine
Ellipticine (NSC 71795) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. Group: Inhibitors. Alternative Names: 5,11-DIMETHYLPYRIDO[4,3-B]CARBAZOLE;5,11-DIMETHYLPYRIDO[4.3:B]CARBAZOLE;5,11-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE;ELLIPTICINE;3-b)carbazole,5,11-dimethyl-6h-pyrido(;icig770;ELLIPTICINE, FOR FLUORESCENCE;ELLIPTICINE(RG). CAS No. 519-23-3. Molecular formula: C17H14N2. Mole weight: 246.31. Density: 1.257±0.06 g/cm³ (20 ºC 760 Torr). Catalog: ACM519233.
Elsulfavirine
Elsulfavirine is a new-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) being developed by Viriom for the treatment and prevention of human immunodeficiency virus (HIV) infections. It is the prodrug of the active compound VM-1500A, a small molecule selective NNRTI, which prevents HIV replication. In June 2017, elsulfavirine received its first global approval in Russia for the treatment of HIV-1 infections in combination with other antiretroviral medicines. Other formulations of this drug are also being evaluated in preclinical and phase II studies for the treatment of HIV infections and/or pre-exposure and post-exposure prophylaxis. Group: Inhibitors. Alternative Names: Elsulfavirine; Elpida. CAS No. 868046-19-9. Molecular formula: C24H17BrCl2FN3O5S. Mole weight: 629.28. Appearance: Solid powder. Purity: >98%. IUPACName: N-(4-{2-[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]acetamido}-3-chlorobenzenesulfonyl)propanamide. Canonical SMILES: CCC (NS (=O) (C1=CC=C (NC (CC2=CC=C (Br)C (OC3=CC (C#N)=CC (Cl)=C3)=C2F)=O)C (Cl)=C1)=O)=O. Catalog: ACM868046199.