BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| OF4949 IV | OF4949 IV is an aminopeptidase B produced by Penicillum rugulosum OF4949. Synonyms: OF 4949IV; OF 4949-IV; OF4949IV. CAS No. 107140-31-8. Molecular formula: C22H24N4O7. Mole weight: 456.4. |  |
| Oganomycin A | Oganomycin A is produced by the strain of Str. oganonensis Y-G 19Z. It is more stable than cephalosporin and resistant to gram-positive and negative bacteria. And it is more effective against gram-negative bacteria than gram-positive bacteria. CAS No. 75794-94-4. Molecular formula: C24H27N3O13S2. Mole weight: 629.61. | |
| Oganomycin B | Oganomycin B is produced by the strain of Str. oganonensis Y-G 19Z. It is more stable than cephalosporin and resistant to gram-positive and negative bacteria. And it is more effective against gram-negative bacteria than gram-positive bacteria. CAS No. 75794-96-6. Molecular formula: C24H27N3O10S. Mole weight: 549.55. | |
| Oidiolactone A | Oidiolactone A is a diterpenoid produced by Oidiodendron griseum CL37215. It inhibits LPS-induced IL-1β and TNF-α activity with IC50 values of 1.5 and 4.7 μmol/L. Synonyms: PR-1388; PR 1388; PR1388. CAS No. 90578-11-3. Molecular formula: C17H20O6. Mole weight: 320.3. | |
| Okadaic acid potassium salt | Okadaic acid potassium salt, originally derived from marine dinoflagellates, Prorocentrium sp., is a potent, cell permeable inhibitor of serine/threonine protein phosphatases. It inhibits protein phosphatase 1 (IC50 = 3-15 nM) and protein phosphatase 2A (IC50 = 0.1-1 nM). Synonyms: 35-Demethyl-DTX 1 Potassium Salt. CAS No. 209266-79-5. Molecular formula: C44H68O13K. Mole weight: 844.10. | |
| Okicenone | Okicenone is originally isolated from Str. sp. KO-3599 and it has the effect of killing tumor cells. Synonyms: 3,4-Dihydro-4,6,9-trihydroxy-8-methyl-1(2H)-anthracenone; 1(2H)-Anthracenone, 3,4-dihydro-4,6,9-trihydroxy-8-methyl-. Grade: >98 %. CAS No. 137018-54-3. Molecular formula: C15H14O4. Mole weight: 258.27. | |
| Oleficin | It is originally isolated from Str. sp. 461. It is resistant to gram-positive bacteria and effective against subcutaneous transplantation of Yoshida sarcoma. Synonyms: 4-[15-[(2,6-Dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14,16-trimethyl-1-oxo-2,4,6,8,10,12-heptadecahexenyl]-2,5-dihydro-3-hydroxy-1-methyl-5-oxo-1H-pyrrole-2-propanoic acid; LS-136996. Grade: 95% by HPLC. CAS No. 12764-54-4. Molecular formula: C34H47NO9. Mole weight: 613.74. | |
| Oligomycin D | Oligomycin D is a macrolide compound produced by Streptomyces, which can inhibit mitochondrial F1FO-ATPase. Synonyms: Rutamycin; 26-demethyloligomycin A; A 272; RR 32705; Rutamycin A. Grade: >95% by HPLC. CAS No. 1404-59-7. Molecular formula: C44H72O11. Mole weight: 777.03. | |
| Oligomycin E | It is a minor metabolite from the oligomycin complex produced by several species of streptomyces. It exhibits weak antibacterial activity and is considerably weaker as an antifungal agent. Synonyms: (1R,2'S,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28R,29R)-22-ethyl-5',6'-dihydro-7,11,14,15,28-pentahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,3',9,13(4'H)-tetrone; 26-hydroxy-28-oxo-Oligomycin A; [1R-[1R*,4E,5'S*,6S*,6'S*(R*),7R*,8S*,10R*,11R*,12S*,14R*,15S*,16R*,18E,20E,22R*,25S*,27S*,28R*,29R*]]-22-Ethyl-5',6'-dihydro-7,11,14,15,28-pentahydroxy-6'-(2-hydroxypropyl)-5',6,8,10,12,14,16,28,29-nonamethyl-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,3',9,13(4'H)-tetrone. Grade: >95% by HPLC. CAS No. 110231-34-0. Molecular formula: C45H72O13. Mole weight: 821.05. | |
| Olivanic acid | Olivanic acid is a β-lactam antibiotic produced by Str. olivaceus. It has anti-gram-positive bacteria and gram-negative bacteria activity, and has the effect of inhibiting β-lactamase. Synonyms: Olivanicacid. CAS No. 64761-66-6. Molecular formula: C11H14N2O4S. Mole weight: 270.31. | |
| Olivetonide | Olivetonide. CAS No. 3734-54-1. Molecular formula: C14H16O4. Mole weight: 248.27. | |
| Olivetonide dimethylether | Olivetonide dimethylether. | |
| Olivetoric acid | It occurs in lichens and forms a purplish red color with a solution of ferric chloride. Mainly used in chemical research. Synonyms: Benzoic acid, 2,4-dihydroxy-6-(2-oxoheptyl)-, 4-carboxy-3-hydroxy-5-pentylphenyl ester; beta-Resorcylic acid, 6-(2-oxoheptyl)-, 4-carboxy-3-hydroxy-5-pentylphenyl ester; 4-[2-(2-Oxoheptyl)-4,6-dihydroxybenzoyloxy]-6-pentylsalicylic acid; 2,4-Dihydroxy-6-(2-oxoheptyl)benzoic acid 4-carboxy-3-hydroxy-5-pentylphenyl ester; 4,6-Dioxy-2-(β-oxo-n-heptyl)-benzoesaeure-(5-oxy-4-carboxy-3-n-amyl-phenylester); β-Resorcylic acid, 6-(2-oxoheptyl)-, 4-carboxy-3-hydroxy-5-pentylphenyl ester. Grade: 99%. CAS No. 491-47-4. Molecular formula: C26H32O8. Mole weight: 472.53. | |
| Olivomycin | Olivomycin is an antitumor antibiotic produced by Actinomyces (or Streptomyces) olivoreticuli. It is used for the treatment of testicular neoplasms, tonsillar tumors and reticulosarcoma with peripheral nodes. Synonyms: Toyomycin R; Olivomicina; Olivomycinum. CAS No. 11006-70-5. Molecular formula: C45H64O21. Mole weight: 941. | |
| Olivomycin A | Olivomycin A is originally isolated from Str. olivoreticuli. It has strong activity against gram-positive bacteria and weak activity against gram-negative bacteria. Synonyms: Olivomycin I; NSC-76411; Olivomycin D, 3(B)-O-(2,6-dideoxy-3-C-methyl-4-O-(2-methyl-1-oxopropyl)-alpha-L-arabino-hexopyranosyl)-. CAS No. 6988-58-5. Molecular formula: C58H84O26. Mole weight: 1197.27. | |
| OM-173αB | OM-173αB is a quinone bacterial metabolite originally isolated from Streptomyces hebeiensis, displaying antimicrobial activity. It is effective against mycoplasma and fungus. Synonyms: OM173-alphaB. CAS No. 88293-08-7. Molecular formula: C17H18O7. Mole weight: 334.3. | |
| OM-173αE | OM-173αE is a quinone bacterial metabolite originally isolated from Streptomyces hebeiensis, displaying antimicrobial activity. It is effective against mycoplasma and fungus. Synonyms: OM173-alphaE. CAS No. 88293-10-1. Molecular formula: C17H16O7. Mole weight: 332.3. | |
| OM-173βE | OM-173βE is a quinone bacterial metabolite originally isolated from Streptomyces hebeiensis, displaying antimicrobial activity. It is effective against mycoplasma and fungus. Synonyms: OM173-betaE. CAS No. 88293-11-2. Molecular formula: C16H16O6. Mole weight: 304.29. | |
| O-Methyl-4-hydroxy mellein | O-Methyl-4-hydroxy mellein. Synonyms: 1H-2-Benzopyran-1-one, 3,4-dihydro-4-hydroxy-8-methoxy-3-methyl-; methyl-4-hydroxy mellein; 3,4-dihydro-4-hydroxy-8-methoxy-3-methyl-1H-2-Benzopyran-1-one; 4-hydroxy-8-O-methylmellein. CAS No. 72327-12-9. Molecular formula: C11H12O4. Mole weight: 208.21. | |
| O-Methylmellein | It is the constituent of Septoria nodorum. Synonyms: 1H-2-Benzopyran-1-one, 3,4-dihydro-8-methoxy-3-methyl-, (3R)-; (R)-O-Methylmellein; (R)-8-methoxy-3-methylisochroman-1-one; (3R)-8-Methoxy-3-methyl-3,4-dihydro-1H-isochromen-1-one; (3R)-O-Methylmellein. CAS No. 76985-75-6. Molecular formula: C11H12O3. Mole weight: 192.21. | |
| O-Methylsterigmatocystin | A xanthone isolated from several species of aspergillus including A. flavus, A. parasiticus, A. versicolor and B. piluliferum. It is a carcinogenic precursor of aflatoxin, and structurally related to the aflatoxins. Synonyms: OMST; 8-O-Methylsterigmatocystin; O-Methyl sterigmatocystin; 7-O-Methylsterigmatocystin; 7H-Furo(3',2':4,5)furo(2,3-c)xanthen-7-one, 3a,12c-dihydro-6,8-dimethoxy-, (3aR-cis)-; Sterigmatocystin, O-methyl-; 3aR,12cS-dihydro-6,8-dimethoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one. Grade: >95% by HPLC. CAS No. 17878-69-2. Molecular formula: C19H14O6. Mole weight: 338.31. | |
| Oosponol | Oosponol is a natural compound which can be isolated from Gloeophyllum abietinum, Hormotilopsis, etc. Synonyms: Lenzitin; 4-Glycolyl-8-hydroxy-isocoumarin. Grade: 98%. CAS No. 146-04-3. Molecular formula: C11H8O5. Mole weight: 220.18. | |
| Oosporein | Oosporein is a quinone antibiotic produced by the strain of Oospora colorans, etc. It is resistant to gram-positive bacteria. Synonyms: NSC 88466; BRN 1892735; 3,3',6,6'-Tetrahydroxy-5,5'-dimethyl-2,2'-bi-p-benzoquinone. Grade: ≥95%. CAS No. 475-54-7. Molecular formula: C14H10O8. Mole weight: 306.22. | |
| OPC 15161 | OPC 15161 is an inhibitor of superoxide anion generation with IC50 of 2.8 x 10(-5) mol/L. Synonyms: OPC-15161. CAS No. 121071-92-9. Molecular formula: C18H21N3O3. Mole weight: 327.4. | |
| Orchinol | Orchinol is an aromatic derivative of antibiotic originally isolated from Rhizoctonia repens and has antifungal activity. Synonyms: 9,10-Dihydro-5,7-dimethoxyphenanthren-2-ol. Grade: >98%. CAS No. 41060-20-2. Molecular formula: C16H16O3. Mole weight: 256.30. | |
| Orfamide A | It is the major component of a family of cyclic lipopeptides produced by pseudomonas fluorescens pf-5. It is a moderate antifungal agent. It has a profound effect on the swarming motility of bacteria on agar surfaces. Synonyms: N-(3-hydroxy-1-oxotetradecyl)-L-leucyl-D-α-glutamyl-D-allothreonyl-D-alloisoleucyl-L-leucyl-D-seryl-L-leucyl-L-leucyl-D-seryl-L-valine, (10→3)-lactone. Grade: >98% by HPLC. CAS No. 939960-34-6. Molecular formula: C64H114N10O17. Mole weight: 1295.65. | |
| Orfamide B | It is a component of a family of cyclic lipopeptides produced by pseudomonas fluorescens pf-5. Synonyms: N-(3-hydroxy-1-oxotetradecyl)-L-leucyl-D-α-glutamyl-D-allothreonyl-D-valyl-L-leucyl-D-seryl-L-leucyl-L-leucyl-D-seryl-L-valine, (10→3)-lactone. Grade: >98% by HPLC. CAS No. 939960-35-7. Molecular formula: C63H112N10O17. Mole weight: 1281.62. | |
| Orsellinic acid | Orsellinic acid is from Chaetomium globosum endophytic. Orsellinic acid can block platelet activating factor (PAF)-mediated neuronal apoptosis without affecting G-protein coupled receptor (PAFR)-mediated neuroprotection, and it can effectively attenuate PAFR-independent neuronal apoptosis. It is a novel benzoquinone ring precursor for antroquinonol and 4-acetylantroquinonol B. It is formed from acetyl-coenzyme Q (CoQ) and malonyl-CoA via polyketide pathway. Synonyms: o-Orsellinic acid; 4,6-Dihydroxy-o-toluic acid. Grade: 99.0%. CAS No. 480-64-8. Molecular formula: C8H8O4. Mole weight: 168.15. | |
| Oryzoxymycin | It is produced by the strain of Str. venezulae Var. oryzoxymyceticus. Oryzoxymycin has anti-gram-negative bacteria activity. Synonyms: BRN 2857392; 1,3-Cyclohexadiene-1-carboxylic acid, 6-amino-5-hydroxy-, 1-carboxyethyl ester, (5S-(1(S*), 5-alpha,6-beta))-. Grade: >98%. CAS No. 12640-81-2. Molecular formula: C10H13NO5. Mole weight: 227.21. | |
| Ossamycin | Ossamycin is a macrolide antibiotic produced by the strain of Str. hygroscopicus, Var. ossamyceticus C 8158. It has anti-fungal effect, and it has weaker anti-gram-positive bacterial effect. It inhibits L cells, Epstein-Barr ascites cancer cells, KB cells, sarcoma-180 cells, L-1210 cells, HeLa cells in cell culture with IC50s (μg/mL) of 0.007, 0.008, 0.005, 0.008, 0.003, 0.005, respectively. It has no antitumor effect in in vivo animal test. Synonyms: Antibiotic NK 154183B. Grade: ≥98%. CAS No. 11015-84-2. Molecular formula: C49H85NO14. Mole weight: 912.20. | |
| Ostreogrycin B3 | It is produced by the strain of Str. ostreogriseus NRRL 2558 (NCIB 8792). It has anti-gram positive bacterial activity, and Ostreogrycin A has stronger antibacterial activity than other components. Ostreogrycin A or G has synergistic antibacterial effect with each component of Ostreogrycin B. The Complex has protective effect on mice infected with bacteria by subcutaneous or oral administration. Synonyms: Virginiamycin-S1; N-(3-Hydroxypicolinoyl)-cyclo[L-Thr*-D-Abu-L-Pro-4-(dimethylamino)-N-methyl-L-Phe-4-oxo-5-hydroxy-L-Hpr-L-phenyl-Gly-]. CAS No. 31508-69-7. Molecular formula: C45H54N8O11. Mole weight: 882.96. | |
| Oudemansin A | It is an antibiotic produced by the strain of Oudemansiella mucida Xerula melanctricha. It acts on fungi to inhibit the synthesis of protein, RNA and DNA. Synonyms: methyl (2E,3S,4S,5E)-4-methoxy-2-(methoxymethylene)-3-methyl-6-phenylhex-5-enoate; Oudemansin; 5-Hexenoic acid, 4-methoxy-2-(methoxymethylene)-3-methyl-6-phenyl-, methyl ester, (S-(R*,R*-(E,E)))-; (-)-oudemansin A; 5-Hexenoic acid, 4-methoxy-2-(methoxymethylene)-3-methyl-6-phenyl-, methyl ester, (2E,3R*,4R*,5E)-(-)-. CAS No. 73341-71-6. Molecular formula: C17H22O4. Mole weight: 290.35. | |
| Oudemansin B | It is an antibiotic produced by the strain of Oudemansiella mucida Xerula melanctricha. It acts on fungi to inhibit the synthesis of protein, RNA and DNA. Synonyms: (-)-oudemansin B; 5-Hexenoic acid, 6-(4-chloro-3-methoxyphenyl)-4-methoxy-2-(methoxymethylene)-3-methyl-, methyl ester, (2E,3S,4S,5E)-. CAS No. 87081-56-9. Molecular formula: C18H23ClO5. Mole weight: 354.83. | |
| Oudenone | It is produced by the strain of Oudemansiella sp. 10F. It is an oxygen-containing heterocyclic antibiotic. It has weak antibacterial and fungal activity. Oudenone of more than 3.13 mg/kg has antihypertensive effect on spontaneous hypertension in rats by intraperitoneal injection or oral administration. Synonyms: 1,3-Cyclopentanedione, 2-(dihydro-5-propyl-2(3H)-furylidene)-, (S)-; 2-[(S)-Tetrahydro-5-propylfuran-2-ylidene]-1,3-cyclopentanedione. Grade: ≥95%. CAS No. 31323-50-9. Molecular formula: C12H16O3. Mole weight: 208.25. | |
| Ovoic acid | It is a secondary metabolite of Lasallia species, a genus of lichenized fungi in the family Umbilicariaceae. Synonyms: 4-[(2,4-Dihydroxy-6-methylbenzoyl)oxy]-2-methoxy-6-methylbenzoic acid 4-carboxy-3-hydroxy-5-methylphenyl ester; Benzoic acid, 4-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-2-methoxy-6-methyl-, 4-carboxy-3-hydroxy-5-methylphenyl ester. CAS No. 76788-86-8. Molecular formula: C25H22O10. Mole weight: 482.44. | |
| Oxamicetin | Oxamicetin is produced by the strain of Arthrobacter oxamicetus B 302-B 75. It's a nucleoside antibiotic. It has anti-bacterial, mycobacterium effects. It has protective effect on intramuscular injection in mice infected with Staphylococcus aureus and Escherichia coli, but oral administration is not effective. It inhibits pathogenic leptospirosis at 0.1-0.5 μg/mL, and inhibits non-pathogenic leptospirosis at 10-40 μg/mL. Synonyms: 4''-Hydroxyamicetin; Antibiotic BU-1848; Oxamycetin. CAS No. 52665-75-5. Molecular formula: C29H42N6O10. Mole weight: 634.68. | |
| Oxanosine | It is produced by the strain of Str. capreolus MG 265-CF3. It's a nucleoside antibiotic. It has weak anti-gram-negative effect on peptone AGAR medium but no antibacterial effect on nutrient AGAR medium. It has antagonistic effect on guanine, guanosine and 5'-guanidine. In vitro, it inhibits HeLa cells with IC50 of 32 mg/kg. In mice, it has inhibitory effect on the leukemia L-1210. Synonyms: 1-Oxaguanosine; 5-Amino-3-β-D-ribofuranosylimidazo[4,5-d][1,3]oxazin-7(3H)-one; Imidazo(4,5-d)(1,3)oxazin-7(3H)-one, 5-amino-3-beta-D-ribofuranosyl-. CAS No. 80394-72-5. Molecular formula: C10H12N4O6. Mole weight: 284.23. | |
| Oxasetin | It is produced by the strain of Vaginatispora aquatica HK 1821. It has medium activity against gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Vancomycin-resistant enterococcus faecalis (MIC is 16 μg/mL). It has no activity against gram-negative bacteria and fungi. Molecular formula: C21H29NO4. Mole weight: 359.46. | |
| Oximidine III | It is produced by the strain of Pseudomonas sp. QN05727. It's an anti-tumor antibiotic. It can selectively inhibit the growth of 3Y1 in rat fibroblasts with degeneration of various tumor genes. It inhibits v-H-ras-3Y1, v-src-3Y1 cells and the normal 3Y1 cells with IC50 (nmol/L) of 14, 4.5 and 140, respectively. It stops RAS-or SRC-denatured cells at G1 phase of the cell cycle and increases p21WAF1 expression. Molecular formula: C23H24N2O6. Mole weight: 424.45. | |
| Oxirapentyn | It is produced by the strain of Beauveria felina SANK 136. It has anti-gram-positive bacteria and Mycobacterium activity, but the antibacterial activity is weak. Synonyms: (3R,4aR)-3α-(Acetyloxy)-3,4,7aα,7bβ-tetrahydro-2,2-dimethyl-6aα-(3-methyl-3-buten-1-ynyl)-2H,5aαH-bisoxireno[e,h]-1-benzopyran-6(6aH)-one; 2H,5aH-Bisoxireno[e,h]-1-benzopyran-6(6aH)-one, 3-(acetyloxy)tetrahydro-2,2-dimethyl-6a-(3-methyl-3-buten-1-ynyl)-, (3R,4aR,5aS,6aS,7aS,7bS)-; Oxirapentyne. CAS No. 88205-90-7. Molecular formula: C18H20O6. Mole weight: 332.35. | |
| Oxostenosporic acid | It is a lichen depside. Molecular formula: C23H26O8. Mole weight: 430.45. | |
| Oxyphysodic acid | Oxyphysodic acid. Synonyms: Physodol; 3-Hydroxyphysodic acid; 3,9,10-trihydroxy-6-oxo-7-(2-oxoheptyl)-1-pentylbenzo[b][1,4]benzodioxepine-2-carboxylic acid; 11H-Dibenzo(b,e)(1,4)dioxepin-11-one, 2,4,8-trihydroxy-1-(2-oxoheptyl)-6-pentyl-. CAS No. 53899-46-0. Molecular formula: C26H30O9. Mole weight: 486.51. | |
| Oxypyrrolnitrin | Oxypyrrolnitrin is produced by the strain of Pseudomonas pyrrolnitrica. It is a nitrogen-containing heterocyclic antibiotic. It has anti-gram-positive bacteria, negative bacteria, mycobacterium and fungal effects. Synonyms: 3-chloro-4-(2'-nitro-3'-chloro-6'-hydroxyphenyl) pyrrole. CAS No. 15345-51-4. Molecular formula: C10H6N2O3Cl2. Mole weight: 273.07. | |
| P-132 | P-132 is an antibiotic produced by Microbispora P-132, W-17 and 37-26. It is effective against gram-positive bacteria, fungi and actinomycetes. Synonyms: P 132. Molecular formula: C14H10N2O3. Mole weight: 254.24. | |
| P-2563 III | P-2563 III is an antibiotic produced by Pseudomonas fluorescens P-2563. It is effective against gram-positive and gram-negative bacteria, especially against Pseudomonas. Molecular formula: C12H27N3O8. Mole weight: 341.36. | |
| P-3355 | P-3355 is antibacterial and antifungal antibiotic produced by streptomyces amylovorus. Synonyms: Antibiotic P 3355; P 3355. CAS No. 60046-57-3. Molecular formula: C7H9NO2. Mole weight: 139.15. | |
| P-725C | P-725C is a prostaglandin synthetase inhibitor produced by Penicillum thomii. Synonyms: 6-Hydroxy-2-methyl-5-(1-oxopropyl)-2H-1,4-oxazine-3-carboxylic acid. CAS No. 87979-96-2. Molecular formula: C9H11NO5. Mole weight: 213.19. | |
| PA-1329-E1 | PA-1329-E1 is a nucleoside antibiotic produced by Micromonospora sp. PA-1329. It exhibits activity against Candida albicans. Synonyms: Antibiotic PA-1329-E1. CAS No. 80860-79-3. Molecular formula: C15H23N7O5. Mole weight: 381.39. | |
| PA-31088-II | PA-31088-II is a carbapenem antibiotic produced by Streptomyces tokunonensis PA-31088 and Str. argenteolus PA-39504. Molecular formula: C13H16N2O6S. Mole weight: 328.34. | |
| PA-32413-I | PA-32413-I is a beta-lactam antibiotic produced by Streptomyces clavuigerus PA-32413. It is active against gram-positive and gram-negative bacteria. Synonyms: PA-32413 I; PA 32413 I. Molecular formula: C18H25N5O10S. Mole weight: 503.48. | |
| PA-46101 A | PA-46101 A is a macrolide antibiotic isolated from the culture broth of Streptomyces sp. PA-46101. It is active in vitro against anaerobic Gram-positive and Gram-negative bacteria and also against a limited number of aerobic Gram-positive bacteria. Synonyms: PA 46101 A. CAS No. 130743-11-2. Molecular formula: C52H70O18. Mole weight: 983.1. | |
| PA-46101 B | PA-46101 B is a macrolide antibiotic isolated from the culture broth of Streptomyces sp. PA-46101. It is active in vitro against anaerobic Gram-positive and Gram-negative bacteria and also against a limited number of aerobic Gram-positive bacteria. Synonyms: PA 46101 B. CAS No. 130812-34-9. Molecular formula: C61H86O22. Mole weight: 1171.3. | |
| Pachybasin | Pachybasin is an anthraquinone fungal metabolite isolated from Trichoderma harzianum. It regulates the increase in the number of Trichoderma mycoparasitic coils via cAMP signaling. It inhibits the growth of E. coli, S. aureus, B. subtilis, M. luteus bacteria, C. albicans, S. cerevisiae, A. niger, A. flavus and F. oxysporum fungi. Synonyms: 1-Hydroxy-3-methylanthraquinone; 1-Hydroxy-3-methyl-9,10-anthracenedione. Grade: ≥70%. CAS No. 2549-78-2. Molecular formula: C15H10O3. Mole weight: 238.24. | |
| Pacidamycin 1 | It is produced by the strain of Str. coeruleorubidus AB 1183F-64. It has inhibitory effect on Pseudomonas aeruginosa. It also has effect on a few strains of bacteria such as suppurative staphylococcus and Escherichia coli. Serum can reduce its antibacterial activity, pH also affects its antibacterial activity. pH 6.5, The antibacterial activity of Pacidamycin 1 can be enhanced twice. In vivo test of mice infected with pseudomonas aeruginosa (100 mg/kg·d) showed no protective effect. Synonyms: Butanamide, N-[[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]carbonyl]-L-alanyl-N3-(L-alanyl-3-hydroxy-L-phenylalanyl)-2-amino-N-[(Z)-[(4R,5R)-5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)dihydro-4-hydroxy-2(3H)-furanylidene]methyl]-3-(methylamino)-, (2S,3S)-. CAS No. 121264-05-9. Molecular formula: C41H50N10O12. Mole weight: 874.90. | |
| Pacidamycin 2 | It is produced by the strain of Str. coeruleorubidus AB 1183F-64. It has inhibitory effect on Pseudomonas aeruginosa. It also has effect on a few strains of bacteria such as suppurative staphylococcus and Escherichia coli. Serum can reduce its antibacterial activity, pH also affects its antibacterial activity. Synonyms: Butanamide, N-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-L-alanyl-N3-(L-alanyl-3-hydroxy-L-phenylalanyl)-2-amino-N-[(Z)-[(4R,5R)-5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)dihydro-4-hydroxy-2(3H)-furanylidene]methyl]-3-(methylamino)-, (2S,3S)-. CAS No. 121264-06-0. Molecular formula: C39H49N9O12. Mole weight: 835.86. | |
| Pacidamycin 3 | It is produced by the strain of Str. coeruleorubidus AB 1183F-64. It has inhibitory effect on Pseudomonas aeruginosa. It also has effect on a few strains of bacteria such as suppurative staphylococcus and Escherichia coli. Serum can reduce its antibacterial activity, pH also affects its antibacterial activity. CAS No. 121280-49-7. Molecular formula: C39H49N9O13. Mole weight: 851.86. | |
| Pacidamycin 4N | It is produced by the strain of Streptomyces coeruleorubidus NRRL 18370. It's a Pacidamycin antibiotic. It has the activity against pseudomonas aeruginosa with MIC of 4-16 μg/mL. it has no effect on other gram-negative bacteria and gram-positive bacteria, and no effect on drug-resistant pseudomonas aeruginosa. Molecular formula: C39H45N9O11. Mole weight: 815.83. | |
| Pacidamycin 5 | It is produced by the strain of Str. coeruleorubidus AB 1183F-64. It has inhibitory effect on Pseudomonas aeruginosa. It also has effect on a few strains of bacteria such as suppurative staphylococcus and Escherichia coli. Serum can reduce its antibacterial activity, pH also affects its antibacterial activity. Synonyms: 3,5,8,11-Tetraazatetradecanoicacid,13-amino-9-[[[(Z)-[(4R,5R)-5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)dihydro-4-hydroxy-2(3H)-furanylidene]methyl]amino]carbonyl]-14-(3-hydroxyphenyl)-6,10,11-trimethyl-4,7,12-trioxo-2-(phenylmethyl)-, (2S,6S,9S,10S,13S)-. CAS No. 122855-43-0. Molecular formula: C36H44N8O11. Mole weight: 764.78. | |
| Pacidamycin 5T | It is produced by the strain of Streptomyces coeruleorubidus NRRL 18370. Molecular formula: C36H44N8O12. Mole weight: 780.78. | |
| Pacidamycin D | It is produced by the strain of Streptomyces coeruleorubidus NRRL 18370. It's a Pacidamycin antibiotic. It has the activity against pseudomonas aeruginosa with MIC of 4-16 μg/mL. it has no effect on other gram-negative bacteria and gram-positive bacteria, and no effect on drug-resistant pseudomonas aeruginosa. CAS No. 287107-95-3. Molecular formula: C32H41N9O10. Mole weight: 711.72. | |
| Paclobutrazol | Paclobutrazol is a triazole antifungal drug that inhibits the growth of plants by preventing the biosynthesis of gibberellin (a plant hormone). Uses: Pesticide. Synonyms: (2R,3R)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pentan-3-ol. CAS No. 76738-62-0. Molecular formula: C15H20ClN3O. Mole weight: 293.79. | |
| Padanamide A | Padanamide A is a metabolite produced by marine Streptomyces species. It inhibits cysteine and methionine biosynthesis. Synonyms: Actinoramide A; CHEMBL3633597; CCG-208791. Grade: ≥95%. CAS No. 1314881-80-5. Molecular formula: C31H47N7O9. Mole weight: 661.74. | |
| Paeciloquinone A | It is produced by the strain of Paecilomyces carneus P-177. It can inhibit the epidermal growth factor receptor protein tyrosine kinase. Paeciloquinone A inhibits the V-abl protein tyrosine kinase with IC50 of 0.59 μmol/L. Synonyms: 9,10-Anthracenedione, 1,3,6,8-tetrahydroxy-2-(tetrahydro-2-oxo-3-furanyl)-. CAS No. 162797-33-3. Molecular formula: C18H12O8. Mole weight: 356.28. | |
| Paeciloquinone B | It is produced by the strain of Paecilomyces carneus P-177. It can inhibit the epidermal growth factor receptor protein tyrosine kinase. Synonyms: 2-Anthraceneacetic acid, 9,10-dihydro-1,3,6,8-tetrahydroxy-9,10-dioxo-a-(3-oxobutyl)-. CAS No. 162797-34-4. Molecular formula: C20H16O9. Mole weight: 400.34. | |
| Paeciloquinone C | It is produced by the strain of Paecilomyces carneus P-177. It can inhibit the epidermal growth factor receptor protein tyrosine kinase. Paeciloquinone C inhibits the V-abl protein tyrosine kinase with IC50 of 0.56 μmol/L. Synonyms: 1,3,6,8-tetrahydroxy-2-(hydroxymethyl)-anthraquinone; 2-Hydroxymethyl-1,3,6,8-tetrahydroxy-anthrachinone. CAS No. 92439-42-4. Molecular formula: C15H10O7. Mole weight: 302.23. | |
| Paeciloquinone D | It is produced by the strain of Paecilomyces carneus P-177. It can inhibit the epidermal growth factor receptor protein tyrosine kinase. Synonyms: 2-Anthraceneacetic acid, 9,10-dihydro-1,3,6,8-tetrahydroxy-a-(2-hydroxyethyl)-9,10-dioxo-. CAS No. 162797-35-5. Molecular formula: C18H14O9. Mole weight: 374.30. | |
| Paeciloquinone E | It is produced by the strain of Paecilomyces carneus P-177. It can inhibit the epidermal growth factor receptor protein tyrosine kinase. Synonyms: 2,5-Ethanoanthra[2,3-d]-1,3-dioxepin-7,12-dione, 4,5-dihydro-6,8,10-trihydroxy-2-methyl-, (1R,17R)-. CAS No. 162797-36-6. Molecular formula: C20H16O7. Mole weight: 368.34. | |
| Paeciloquinone F | It is produced by the strain of Paecilomyces carneus P-177. It can inhibit the epidermal growth factor receptor protein tyrosine kinase. Synonyms: 2,5-Epoxyanthra[2,3-b]oxepin-5(2H)-carboxylic acid, 3,4,7,12-tetrahydro-6,8,10-trihydroxy-2-methyl-7,12-dioxo-, (1S,17R)-. CAS No. 162797-37-7. Molecular formula: C20H14O9. Mole weight: 398.32. | |
| Paldimycin | It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacterial effect, but also has weak anti-gram-negative bacterial effect. Paldimycin A has stronger antibacterial activity than Paldimycin B. Synonyms: Antibiotic 273 A1; (5S)-5-[5-[3-[(2R)-2-acetamido-2-carboxyethyl]sulfanyl-2-[[(2R)-2-acetamido-2-carboxyethyl]sulfanylcarbothioylamino]butanoyl]oxy-6-(acetyloxymethyl)-3-hydroxy-4-[5-hydroxy-4-methoxy-6-methyl-5-[(1S)-1-(2-methylpropanoyloxy)ethyl]oxan-2-yl]oxyoxan-2-yl]-2-amino-5-hydroxy-3,6-dioxocyclohexene-1-carboxylic acid; (5S)-5-[5-[3-[(2R)-2-acetamido-2-carboxyethyl]sulfanyl-2-[[(2R)-2-acetamido-2-carboxyethyl]sulfanylcarbothioylamino]butanoyl]oxy-6-(acetyloxymethyl)-3-hydroxy-4-[5-hydroxy-4-methoxy-6-methyl-5-[(1S)-1-[(2S)-2-methylbutanoyl]oxyethyl]oxan-2-yl]oxyoxan-2-yl]-2-amino-5-hydroxy-3,6-dioxocyclohexene-1-carboxylic acid. CAS No. 102426-96-0. Molecular formula: C87H126N8O46S6. Mole weight: 2212.34. | |
| Paldimycin A | It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacterial effect, but also has weak anti-gram-negative bacterial effect. Paldimycin A has stronger antibacterial activity than Paldimycin B. Synonyms: Antibiotic 273 A1-alpha; L-Cysteine, N-acetyl-, [2-[[2-(acetylamino)-2-carboxyethyl]thio]-1-carboxypropyl]carbamodithioate(ester), 4'-ester with 5-[6-O-acetyl-3-O-[2,6-dideoxy-3-O-methyl-4-C-[1-(2-methyl-1-oxobutoxy)ethyl]-a-L-lyxo-hexopyranosyl]-b-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-1-cyclohexene-1-carboxylic acid; 2-Amino-5-(3-O-(2,6-dideoxy-4-C-((1S)-1-hydroxyethyl)-3-O-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-allopyranosyl)-5-hydroxy-3,6-dioxo-1-cyclohexene-1-carboxylic acid, 4'-(3-(((2R)-2-acetamido-2-carboxyethyl)thio)-2-((dithiocarboxy)amino)butyrate), 6'-acetate, 4''-C-((2S)-2-methylbutyrate), S-ester with N-acetyl-L-cysteine. CAS No. 101411-70-5. Molecular formula: C44H64N4O23S3. Mole weight: 1113.18. | |
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