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PF-1057B
PF-1057B is an antibiotic produced by Chaetomella cinnamomea PF-1057. Synonyms: PF 1057B; PF1057B. CAS No. 89020-47-3. Molecular formula: C33H58O11S2. Mole weight: 694.9.
PF-1057C
PF-1057C is an antibiotic produced by Chaetomella cinnamomea PF-1057. Synonyms: PF 1057C; PF1057C. CAS No. 89020-48-4. Molecular formula: C35H60O12S2. Mole weight: 737.
PF-1057D
PF-1057D is an antibiotic produced by Chaetomella cinnamomea PF-1057. Synonyms: PF 1057D; PF1057D. Molecular formula: C33H58O11S2. Mole weight: 694.9.
PF-1092A
PF-1092A is a nonsteroidal progesterone receptor ligand produced by Penicillium oblatum. It was shown to competitively inhibit [3H]-progesterone binding to porcine uteri cytosol preparations with IC50 of 3.0 x 10 nM. Synonyms: PF 1092A; PF1092A. Molecular formula: C17H20O5. Mole weight: 304.34.
PF-1092B
PF-1092B is a nonsteroidal progesterone receptor ligand produced by Penicillium oblatum. It was shown to competitively inhibit [3H]-progesterone binding to porcine uteri cytosol preparations with IC50 of 2.2 x 10(2) nM. Synonyms: PF 1092B; PF1092B. Molecular formula: C17H20O5. Mole weight: 304.34.
PF-1092C
PF-1092C is a nonsteroidal progesterone receptor ligand produced by Penicillium oblatum. It was shown to competitively inhibit [3H]-progesterone binding to porcine uteri cytosol preparations with IC50 of 2.2 x 10(3) nM. Synonyms: PF 1092C; PF1092C. Molecular formula: C15H18O4. Mole weight: 262.3.
Phanerosporic acid
Phanerosporic acid is a fungal secondary metabolite isolated from Phanerochaete chrysosporium. It has antibacterial and antifungal activities. Synonyms: (-)-Phanerosporic Acid; Benzoic acid, 2,4-dihydroxy-6-[(14R)-14-hydroxypentadecyl]-. Grade: ≥95%. CAS No. 124709-28-0. Molecular formula: C22H36O5. Mole weight: 380.52.
Phebestin
It is produced by the strain of Str. sp. MJ 716-m3. It has inhibitory effect on aminopeptidase N (AP-N), AP-A, AP-B with IC50 (μg/mL) of 0.18, 9.0 and 9.1, respectively, but it has no antimicrobial activity (100 μg/mL). Synonyms: N-((2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbuty)-L-valyl-L-phenylalanine; ((2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl)-L-valyl-L-phenylalanine; L-Phenylalanine, N-((2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbuty)-L-valyl-. Grade: ≥99%. CAS No. 187402-73-9. Molecular formula: C24H31N3O5. Mole weight: 441.52.
Phellinsin
It is produced by the strain of Phellinus sp. PL3. It selectively inhibits the activity of the chitin synthase I and II with IC50 (μg/mL) of 76 and 28, respectively. It has the antifungal activity on Colletotrichum lagenarium, Pyricularia oryzae, aspergillus fumigatus and Trichophyton mentagrophytes and so on (MIC is 12.5-50 μg/mL). Synonyms: Phellinsin A. Molecular formula: C18H14O8. Mole weight: 358.30.
Phenarctin
Phenarctin is obtained from Nephroma arcticum. Synonyms: 3-Hydroxy-4-(methoxycarbonyl)-2,5,6-trimethylphenyl 3,5-diformyl-2,4-dihydroxy-6-methylbenzoate; β-Resorcylic acid, 3,5-diformyl-6-methyl-, 4-ester with methyl 3,5,6-trimethyl-β-resorcylate (8CI). CAS No. 27839-39-0. Molecular formula: C21H20O9. Mole weight: 416.38.
It is produced by the strain of Str. sp. 833. It is a phenazine Substance that has the protective effect of new neuron cells. It can scavenge free radicals, protect N18-RE 105 nerve cells from glutamate toxicity, and inhibit lipid peroxidation. It inhibits glutamate toxicity in N18-RE-105 cells with EC50 of 0.34 μg/mL. Molecular formula: C28H20N4O3. Mole weight: 460.48.
Phenazostatin B
It is produced by the strain of Str. sp. 833. It is a phenazine Substance that has the protective effect of new neuron cells. It can scavenge free radicals, protect N18-RE 105 nerve cells from glutamate toxicity, and inhibit lipid peroxidation. It inhibits glutamate toxicity in N18-RE-105 cells with EC50 of 0.33 μg/mL. Molecular formula: C32H26N4O4. Mole weight: 530.57.
Phenazostatin C
It is produced by the strain of Streptomyces sp. 833. It can protect N18-RE-105 nerve cells from glutamate toxicity with EC50 of 0.37 μmol/L (similar to Phenazinastatin A) and inhibit lipid peroxidation. It has low toxicity, and 100 μmol/L of Phenazostatin C is not cytotoxic. Molecular formula: C30H22N4O4. Mole weight: 502.52.
Phencomycin
It is produced by the strain of Str. sp. HIL Y-9031725. It has weak anti-gram-positive bacterial effect, but also has inhibitory effect against physiologically important enzyme like renin (IC50 is 440 μg/mL). Synonyms: Phenazine-1,6-dicarboxylic acid 1-methyl ester; 1,6-Phenazinedicarboxylic acid, monomethyl ester; Phenocomycin. CAS No. 146615-53-4. Molecular formula: C15H10N2O4. Mole weight: 282.25.
Phenelfamycin A
It is produced by the strain of Str. violaceoniger AB 9991-80, Str. violaceoniger AB 1047T-33. It has effect against anaerobic bacteria. CAS No. 118498-91-2. Molecular formula: C51H71NO15. Mole weight: 938.11.
Phenelfamycin B
It is produced by the strain of Str. violaceoniger AB 9991-80, Str. violaceoniger AB 1047T-33. It has effect against anaerobic bacteria. CAS No. 118498-92-3. Molecular formula: C51H71NO15. Mole weight: 938.11.
Phenelfamycin C
It is produced by the strain of Str. violaceoniger AB 9991-80, Str. violaceoniger AB 1047T-33. It has effect against anaerobic bacteria. CAS No. 118498-93-4. Molecular formula: C58H83NO18. Mole weight: 1082.28.
Phenelfamycin F
It is produced by the strain of Str. violaceoniger AB 9991-80, Str. violaceoniger AB 1047T-33. It has effect against anaerobic bacteria. Synonyms: Ganefromycin-β; Antibiotic LL-E 19020b; Ganefromycin b; LL-E 19020b; Benzeneacetic acid, 2-[2-[[7-[5-(6-carboxy-1,3,5-hexatrienyl)tetrahydro-4-hydroxy-2-furanyl]-6-methoxy-5-methyl-2,4-octadienyl]amino]-1-[[[O-2,6-dideoxy-3-O-methyl-a-L-lyxo-hexopyranosyl-(1,4)-O-2,6-dideoxy-3-O-methyl-b-L-ribo-hexopyranosyl-(1,4)-2,6-dideoxy-3-O-methyl-a-L-lyxo-hexopyranosyl]oxy]methyl]-2-oxoethyl]tetrahydro-2,3-dihydroxy-5,5-dimethyl-6-(1,3-pentadienyl)-2H-pyran-4-yl ester. Grade: >95%. CAS No. 114451-30-8. Molecular formula: C65H95NO21. Mole weight: 1226.44.
Phenochalasin A
It is produced by the strain of Phomopsis sp. FT-0211. Phenochalasin A (less than 20 μmol/L) can reduce the number and size of lipid droplets in macrophages without showing any cytotoxicity. Molecular formula: C28H33NO7. Mole weight: 495.56.
Phenochalasin B
It is produced by the strain of Phomopsis sp. FT-0211. Phenochalasin A (less than 20 μmol/L) can reduce the number and size of lipid droplets in macrophages without showing any cytotoxicity. Synonyms: Antibiotic Mer-WF 1726; 4'-Methoxycytochalasin. CAS No. 207679-46-7. Molecular formula: C29H35NO8. Mole weight: 525.59.
Phenylalanyl-histidine
Phenylalanylhistidine is a dipeptide composed of phenylalanine and histidine. Synonyms: Phe-his; L-phenylalanyl-L-histidine. CAS No. 33367-37-2. Molecular formula: C15H18N4O3. Mole weight: 302.33.
Phenylalanyl-lysine
Phenylalanyl-lysine is a dipeptide composed of phenylalanine and lysine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: 3-Phenyl-L-Ala-L-Lys-OH; L-Phe-L-Lys-OH; N2-(3-Phenyl-L-alanyl)-L-lysine; Phe-Lys-OH; L-Lysine, L-phenylalanyl-; (S)-6-Amino-2-((S)-2-amino-3-phenyl-propionylamino)-hexanoic acid; H-FK-OH; L-phenylalanyl-L-lysine. Grade: ≥95%. CAS No. 6456-72-0. Molecular formula: C15H23N3O3. Mole weight: 293.36.
Phenylalanyl-prolyl Diketopiperazine
Cyclo(D-Phe-L-Pro) is a cyclodipeptide phytotoxin produced by Alternaria alternata and streptomyces rochei. Synonyms: L-Phe-L-Pro lactam; (3R,8aS)-Cyclo(phenylalanylprolyl); phenylalanyl-prolyl diketopiperazine; Cyclo(L-prolyl-D-phenylalanyl). Grade: 98.0%. CAS No. 26488-24-4. Molecular formula: C14H16N2O2. Mole weight: 244.29.
Phenylalanyl-threonine
Phenylalanyl-threonine is a dipeptide composed of phenylalanine and threonine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Threonine, L-phenylalanyl-; Phe-Thr; H-FT-OH; L-Phe-L-Thr; L-phenylalanyl-L-threonine. Grade: ≥98%. CAS No. 51352-44-4. Molecular formula: C13H18N2O4. Mole weight: 266.29.
Phenylpyropene B
It is produced by the strain of Penicillum griseofulvum F 1959. It can inhibit ACAT activity with IC50 of 12.8 μmol/L. CAS No. 556013-83-3. Molecular formula: C30H36O7. Mole weight: 508.60.
Phenylpyropene C
It is produced by the strain of Penicillum griseofulvum F 1959. It can inhibit ACAT activity with IC50 of 16.0 μmol/L. Molecular formula: C28H34O5. Mole weight: 450.57.
Phepropeptin A
It is produced by the strain of Streptomyces sp. MK600-cF7. It can inhibit the activity of Proteasome with IC50 of 21.0 μg/mL. Molecular formula: C37H58N6O6. Mole weight: 682.89.
Phepropeptin B
It is produced by the strain of Streptomyces sp. MK600-cF7. It can inhibit the activity of Proteasome with IC50 of 11.0 μg/mL. Synonyms: cyclo(-L-Leu-D-Phe-L-Pro-L-Phe-D-Leu-L-Val-). Molecular formula: C40H56N6O6. Mole weight: 716.91.
Phepropeptin C
It is produced by the strain of Streptomyces sp. MK600-cF7. It can inhibit the activity of Proteasome with IC50 of 12.5 μg/mL. Molecular formula: C38H60N6O6. Mole weight: 696.92.
Phepropeptin D
It is produced by the strain of Streptomyces sp. MK600-cF7. It can inhibit the activity of Proteasome with IC50 of 7.8 μg/mL. Molecular formula: C41H58N6O6. Mole weight: 730.93.
Phleomycin E
It is produced by the strain of Streptoverticillium verticillum 843-1. It's a heteropeptide antibiotic. It has anti-gram-positive bacteria, negative bacteria and mycobacterium effects. It extends the survival time of mice transplanted with Ehrman's ascites cancer by 300 percent with MED of 12.5-25 μg/mL. It inhibits airy entity carcinoma in mice with IC50 of 0.31 μg/mL. Synonyms: N1-[4-[[[[4-[[Aminoiminomethyl]amino]butyl]amino](imino)methyl]amino]butyl]-7,8-dihydrobleomycinamide; Bleomycinamide, N1-[4-[[[[4-[(aminoiminomethyl)amino]butyl]amino]iminomethyl]amino]butyl]-7,8-dihydro-. CAS No. 11031-13-3. Molecular formula: C60H97N23O21S2. Mole weight: 1540.68.
Phleomycin F
It is produced by the strain of Streptoverticillium verticillum 843-1. It's a heteropeptide antibiotic. It has anti-gram-positive bacteria, negative bacteria and mycobacterium effects. It extends the survival time of mice transplanted with Ehrman's ascites cancer by 300 percent with MED of 25-50 μg/mL. Synonyms: Bleomycin B4; Dehydrophleomycin E; N1-[4-[(Aminoiminomethyl)[4-[(aminoiminomethyl)amino]butyl]amino]butyl]bleomycinamide; Bleomycinamide, N1-[4-[(aminoiminomethyl)[4-[(aminoiminomethyl)amino]butyl]amino]butyl]-. CAS No. 9060-11-1. Molecular formula: C60H95N23O21S2. Mole weight: 1538.67.
Phoenistatin
It is produced by the strain of Acremonium fusigerum. It's a substance that increases the expression of genes. 3 nmol/L - 1000 μmol/L of Phoenistatin causes more than 3 times the gene expression of the PA1-1 promoter. Molecular formula: C29H40N4O6. Mole weight: 540.65.
Phomaligol A
Phomaligol A is an antibacterial metabolite produced from marine-derived fungus Aspergillus flavus. Synonyms: Butanoic acid, 2-methyl-, (1R,5R)-5-hydroxy-4-methoxy-1,5-dimethyl-2,6-dioxo-3-cyclohexen-1-yl ester, (2S)-. Grade: ≥98%. CAS No. 152204-32-5. Molecular formula: C14H20O6. Mole weight: 284.31.
Phomopsin A
It is an acidic 13-membered cyclic hexapeptide-like metabolite with three unusual amino acids. It is a potent mycotoxin produced by the fungus, phomopsis leptostromiformis. It is an important bioprobe for understanding cellular structural proteins. It selectively binds to the dimeric tubulin at the overlap of vinblastine and maytansine, inhibits the formation of the microtubule spindle to block cell division. Synonyms: 2-Oxa-5,8-diazabicyclo[10.3.1]hexadecane, cyclic peptide deriv.; (2E)-(βS)-3-chloro-β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-(2E)-2,3-didehydroisoleucyl-2,3-didehydro-aspartic acid, cyclic (15→3)-ether; NSC 381839; PMSA; Phomopsin. Grade: >98% by HPLC. CAS No. 64925-80-0. Molecular formula: C36H45ClN6O12. Mole weight: 789.23.
Phomopsinamine
Phomopsinamine is a potent mycotoxin and an effective microtubule inhibitor produced by the fungus, Phomopsis leptostromiformis. Phomopsinamine is formed by hydrolysis of the dicarboxylic acid of phomopsin A. Synonyms: Isoleucinamide, (βS)-3-chloro-β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-2,3-didehydro-, cyclic (15→3)-ether, (2E)-; Phomopsinamine A; (2E)-(βS)-3-chloro-β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-2,3-didehydro-isoleucinamide, cyclic (15→3)-ether; (S)-N-((E)-1-amino-3-methyl-1-oxopent-2-en-2-yl)-1-((3R,4S,7S,10S,11S)-15-chloro-3-ethyl-16,11-dihydroxy-3-methyl-10-(methylamino)-6,9-dioxo-7-(prop-1-en-2-yl)-2-oxa-5,8-diaza-1(1,3)-benzenacycloundecaphane-4-carbonyl)-2,5-dihydro-1H-pyrrole-2-carboxamide. Grade: >95% by HPLC. CAS No. 89085-54-1. Molecular formula: C32H43ClN6O8. Mole weight: 675.17.
Phoslactomycin A
It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Synonyms: Propanoic acid, 2-methyl-, (1S,3R)-3-[(1Z,3Z,5R,7R,8R,9E)-8-(2-aminoethyl)-10-[(2S,3S)-3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl]-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrien-1-yl]cyclohexyl ester; Propanoic acid, 2-methyl-, 3-[8-(2-aminoethyl)-10-(3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl)-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrienyl]cyclohexyl ester, [2S-[2a[1Z(1R*,3S*),3Z,5S*,7S*,8S*,9E],3a]]-; (+)-Phoslactomycin A. CAS No. 122856-25-1. Molecular formula: C29H46NO10P. Mole weight: 599.65.
Phoslactomycin B
It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Synonyms: (+)-Phoslactomycin B; 2H-Pyran-2-one, 6-[(1E,3R,4R,6R,7Z,9Z)-3-(2-aminoethyl)-10-cyclohexyl-3,6-dihydroxy-4-(phosphonooxy)-1,7,9-decatrien-1-yl]-5-ethyl-5,6-dihydro-, (5S,6S)-. CAS No. 122856-26-2. Molecular formula: C25H40NO8P. Mole weight: 513.56.
Phoslactomycin C
It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Synonyms: Phosphazomycin C1; Butanoic acid, 3-methyl-, 3-[8-(2-aminoethyl)-10-(3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl)-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrienyl]cyclohexyl ester. CAS No. 122856-27-3. Molecular formula: C30H48NO10P. Mole weight: 613.67.
Phoslactomycin D
It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Synonyms: Pentanoic acid, 4-methyl-, 3-(8-(2-aminoethyl)-10-(3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl)-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrienyl)cyclohexyl ester. CAS No. 122856-28-4. Molecular formula: C31H50NO10P. Mole weight: 627.70.
Phoslactomycin E
It is produced by the strain of Str. nigrescens. It is the main component, which has weak effect against gram-positive bacteria, but has strong effect against fungi. Synonyms: Cyclohexanecarboxylic Acid, 3-(8-(2-Aminoethyl)-10-(3-Ethyl-3,6-Dihydro-6-Oxo-2H-Pyran-2-Yl)-5,8-Dihydroxy-7-(Phophonooxy)-1,3,9-Decatrienyl)Cyclohexyl Ester. CAS No. 122856-29-5. Molecular formula: C32H50NO10P. Mole weight: 639.71.
Phoslactomycin F
It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Synonyms: Hexanoic acid, 4-methyl-, 3-(8-(2-aminoethyl)-10-(3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl)-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrienyl)cyclohexyl ester. CAS No. 122856-30-8. Molecular formula: C32H52NO10P. Mole weight: 641.73.
Phosmidosine
It is produced by the strain of Str. sp. RK-16. It can inhibit the cell cycle progression and cell morphology recovery of srcts-NRK cells. It has antifungal effect. Synonyms: Phosmidosine A; Adenosine, 7,8-dihydro-8-oxo-, 5'-(methyl(2-pyrrolidinylcarbonyl)phosphoramidate), (S)-; 5'-O-[Methoxy[[[(2S)-pyrrolidin-2α-yl]carbonyl]amino]phosphinyl]-7,8-dihydro-8-oxoadenosine; Adenosine, 7,8-dihydro-8-oxo-, 5'-[methyl N-[(2S)-2-pyrrolidinylcarbonyl]phosphoramidate]. CAS No. 134966-01-1. Molecular formula: C16H24N7O8P. Mole weight: 473.38.
Phosmidosine B
It is produced by the strain of Str. sp. RK-16. It can inhibit the cell cycle progression and cell morphology recovery of srcts-NRK cells. Synonyms: Adenosine, 7,8-dihydro-8-oxo-, 5'-[hydrogen[(2S)-2-pyrrolidinylcarbonyl]phosphoramidate]; Adenosine, 7,8-dihydro-8-oxo-, 5'-[hydrogen (2-pyrrolidinylcarbonyl)phosphoramidate], (S)-. CAS No. 146425-23-2. Molecular formula: C15H22N7O8P. Mole weight: 459.35.
Phosmidosine C
It is produced by the strain of Str. sp. RK-16. Molecular formula: C11H17N6O7P. Mole weight: 376.26.
Phyllosinol
It is produced by the strain of Phyllosticta sp. pH-A. It's an antifungal antibiotic. It has the same effect as Sphaeropsidin and Epoxydon. Synonyms: Epoxydon; Epoxydone; (+)-Parasitenone; (+)-Epoxydon; NSC 93049; Antibiotic 212T2; 7-Oxabicyclo[4.1.0]hept-3-en-2-one, (1R,5R,6R)-; 7-Oxabicyclo[4.1.0]hept-3-en-2-one, [1R-(1alpha,5beta,6alpha)]-. Grade: 95%. CAS No. 24292-29-3. Molecular formula: C7H8O4. Mole weight: 156.14.
Physciosporin
Physciosporin (PHY) is an effective secondary metabolite found in lichens and isolated from Pseudocyphellaria coriacea. It inhibits the motility of lung cancer cells. Synonyms: 2-Chloro-4-formyl-3,8-dihydroxy-1,6,9-trimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-7-carboxylic acid methyl ester; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 2-chloro-4-formyl-3,8-dihydroxy-1,6,9-trimethyl-11-oxo-, methyl ester; methyl 8-chloro-10-formyl-3,9-dihydroxy-1,4,7-trimethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylate; Chlorgranulatin; Methyl 5-chlorovirensate. CAS No. 64662-25-5. Molecular formula: C19H15ClO8. Mole weight: 406.77.
Physodalic acid
It is a lichen depsidone isolated from Hypogymnia physodes. Synonyms: 4-(acetyloxymethyl)-10-formyl-3,9-dihydroxy-1,7-dimethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylic acid; CCRIS 5525; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 9-[(acetyloxy)methyl]-4-formyl-3,8-dihydroxy-1,6-dimethyl-11-oxo-. CAS No. 90689-60-4. Molecular formula: C20H16O10. Mole weight: 416.33.
PI-083
PI-083 is a platelet aggregation inhibitor produced by Streptomyces matensis A-6621. It is active against gram-positive bacteria with MIC of 0.39-3.13 μg/mL. It inhibits platelet aggregation induced by ADP, Arachidonic Acid and collagen with MIC of 30.4, 1.9 and 3.8 μmol/L. It also inhibits KB cell growth with IC50 of 0.026 μmol/L. Synonyms: PI 083; PI083. CAS No. 119341-57-0. Molecular formula: C43H50O16. Mole weight: 822.8.
PI-200
PI-200 is a platelet aggregation inhibitor produced by Streptomyces sp. A7498. It inhibited ADP-induced aggregation of rabbit platelets with IC50 of 3.8 x 10(-4) M. Synonyms: PI 200; PI200. CAS No. 143605-57-6. Molecular formula: C17H26O2. Mole weight: 262.4.
PI-201
PI-201 is a platelet aggregation inhibitor produced by Streptomyces sp. A7498. It inhibited ADP-induced aggregation of rabbit platelets with IC50 of 7.1 x 10(-4) M. Synonyms: PI 201; PI201. CAS No. 143605-56-5. Molecular formula: C17H28O3. Mole weight: 280.4.
Picloram
Picloram is a systemic herbicide used for general woody plant control. Grade: ≥95% by HPLC. CAS No. 1918-2-1. Molecular formula: C6H3Cl3N2O2. Mole weight: 241.46.
Picrolichenic acid
It is a 3-spirobenzofuran heterocyclic compound isolated from Variolaria amara. Synonyms: 6-Hydroxy-2'-methoxy-2,4'-dioxo-4,6'-dipentylspiro[benzofuran-3(2H),1'-[2,5]cyclohexadiene]-5-carboxylic acid; Pikrolichenic acid; Spiro[benzofuran-3(2H),1'-[2,5]cyclohexadiene]-5-carboxylic acid, 6-hydroxy-2'-methoxy-2,4'-dioxo-4,6'-dipentyl-; picrolichenin; NSC 43331; 6-hydroxy-2'-methoxy-2,4'-dioxo-4,6'-dipentyl-2H-spiro[benzofuran-3,1'-cyclohexane]-2',5'-diene-5-carboxylic acid. CAS No. 466-34-2. Molecular formula: C25H30O7. Mole weight: 442.50.
Piericidin B
It is produced by the strain of Str. mobaraensis 16-24. It has anti-fungal, gram-positive bacteria and insect effects, but also has weak anti-gram-negative bacteria effect. Synonyms: Piericidin B1; (-)-Piericidin B1; 4-Pyridinol, 2,3-dimethoxy-6-(10-methoxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraenyl)-5-methyl-, (S-(R*,R*-(all-E)))-; 4-Pyridinol, 2,3-dimethoxy-6-[(2E,5E,7E,9R,10R,11E)-10-methoxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraen-1-yl]-5-methyl-. CAS No. 16891-54-6. Molecular formula: C26H39NO4. Mole weight: 429.59.
Pikromycin
Pikromycin is a macrolide antibiotic that is biosynthesised by Streptomyces venezuelae. It is an inhibitor of Prolyl endopeptidase (PREP) and has an inhibitory effect on E. coli, S. aureus, B. subtilis and mycobacteria. Synonyms: (3R,5R,6S,7S,9R,11E,13S,14R)-14-Ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradec-11-ene-2,4,10-trione; Albomycetin; Amaromycin; Antibiotic B 62169A; [3R-(3R*,5R*,6S*,7S*,9R*,11E,13S*,14R*)]-14-Ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradec-11-ene-2,4,10-trione; Picromycin. Grade: ≥95% by HPLC. CAS No. 19721-56-3. Molecular formula: C28H47NO8. Mole weight: 525.67.
Pilatin
It is produced by the strain of Flagelloscypha pilatii JK 322. Like Marasmic acid, it has inhibitory effects on bacteria and fungi, and has strong inhibitory effects on the incorporation of thymidin and ureidin into DNA and RNA in Ehrlich carcinoma ascites cells. It can cause frameshift mutations in Salmonella typhimuium TA98. Synonyms: 2-Hexenoic acid, 5a,7,8,8a-tetrahydro-3,5a-dihydroxy-7,7-dimethyl-4-formyl-1-oxo-3H,6H,3a,8b-methano-1H-indeno(4,5-c)furan-6-yl ester, (3S-(3-alpha,3a-beta,5a-beta,6-alpha(E),8a-beta,9b-beta))-; 2-Hexenoic acid, 5a,7,8,8a-tetrahydro-4-formyl-3,5a-dihydroxy-7,7-dimethyl-1-oxo-3H,6H-3a,8b-methano-1H-indeno(4,5-c)furan-6-yl ester, (3S-(3alpha,3abeta,5abeta,6alpha(E),8abeta,9bbeta))-. CAS No. 119525-97-2. Molecular formula: C21H26O7. Mole weight: 390.43.
Piloquinone
It is produced by the strain of Str. pilosus. It's a phenanthrene compound. It has inhibitory effect on mycobacterium and protozoa, but the effect is not strong. Synonyms: 9,10-Phenanthrenedione, 1,8-dihydroxy-2-methyl-3-(4-methyl-1-oxopentyl)-; 1,8-Dihydroxy-2-methyl-3-(4-methylpentanoyl)-9,10-phenanthrenedione. CAS No. 25414-26-0. Molecular formula: C21H20O5. Mole weight: 352.38.
Pimprinethine
Pimprinethine is a pyrazoloisoquinolinone antibiotic produced by Streptoverticillium griseocarneum. It has weak anti-Gram-positive bacteria activity. Synonyms: APHE-1. CAS No. 146426-35-9. Molecular formula: C13H12N2O. Mole weight: 212.25.
Pinastric acid
It is a derivative of pulvinic acid and isolated from a terrestrial lichen. It displays antitumour, antiviral and antimicrobial (both antibacterial and antifungal) activities. Synonyms: 4'-Methoxyvulpinic acid; Pianstric acid; (αE)-α-Phenyl-3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylideneacetic acid methyl ester; 2-Phenyl-2-[(2E)-3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylidene]acetic acid methyl ester; Phenyl[(2E)-3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylidene]acetic acid methyl ester; α-[(2E)-3-Hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylidene]benzeneacetic acid methyl ester; Benzeneacetic acid, α-[3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2(5H)-furanylidene]-, methyl ester, (αE)-; methyl (E)-2-(3-hydroxy-4-(4-methoxyphenyl)-5-oxofuran-2(5H)-ylidene)-2-phenylacetate; δ2(5H),α-Furanacetic acid, 3-hydroxy-4-(p-methoxyphenyl)-5-oxo-α-phenyl-, methyl ester. CAS No. 481-64-1. Molecular formula: C20H16O6. Mole weight: 352.34.
Pinselin
It is produced by the strain of Penicillium sp., Pen. amarum. It is a nitrogen-containing heterocyclic antibiotic. It has anti-yeast activity. Synonyms: Pincelin; 9H-Xanthene-1-carboxylic acid, 2,8-dihydroxy-6-methyl-9-oxo-, methyl ester; Cassiollin; 1,7-Dihydroxy-8-methoxycarbonyl-3-methylxanthon. CAS No. 476-53-9. Molecular formula: C16H12O6. Mole weight: 300.26.
Pintulin
It is produced by the strain of Penicillium vulpinum F-4148. In in vitro test, it can inhibit P388, L 1210, HL-60, KB and other tumor cell lines with IC50 (μg/mL) of 0.8, 0.8, 0.8, 0.25, respectively. It has only very weak antibacterial activity against the microorganisms tested. Molecular formula: C14H12O5. Mole weight: 260.24.
Pipacycline
A semi-synthetic tetracycline formed by a mannich condensation of formaldehyde and 4-hydroxyethylpiperazine with tetracyclin. It inhibits the formation of penicillinase, the enzyme that inactivates penicillin in bacteria. It is used in salt form with penicillin V for parenteral use. Synonyms: Mepicycline; Pipacyclinum. Grade: >98% by HPLC. CAS No. 1110-80-1. Molecular formula: C29H38N4O9. Mole weight: 586.63.
Piperafizine A
It is a methylated diketopiperazine formed by the condensation of phenylalanine and is produced by many species in the genus Streptomyces. It exhibits little activity in vitro but potentiates vincristine antitumour potency. Synonyms: 3,6-Dibenzylidene-1-methyl-2,5-dioxopiperazine. Grade: >99% by HPLC. CAS No. 130603-59-7. Molecular formula: C19H16N2O2. Mole weight: 304.34.
Piperazinomycin
It is produced by the strain of Streptoverticillium olivoreticuli subsp. neoenacticus. It has anti-fungal, yeast, some mycobacterium effects, but no anti-bacterial effect. Synonyms: (+)-piperazinomycin; 13-Oxa-4,20-diazatetracyclo[12.2.2.23,6.18,12]heneicosa-8,10,12(19),14,16,17-hexaen-11-ol, (3S,6S)-. CAS No. 83858-82-6. Molecular formula: C18H20N2O2. Mole weight: 296.36.
Piptamine
It is produced by the strain of Piptoporus sp. Lu 9-1. It has broad antibacterial spectrum, it inhibits Staphylococcus aureus, enterococcus faecalis, Bacillus subtilis, Escherichia coli, Candida albicans with MIC (μg/mL) of 0.78-6.25, 1.56, 1.00, 12.5, 6.25, respectively. Molecular formula: C23H41N. Mole weight: 331.58.
Pironetin
Pironetin is a plant growth regulator produced by Streptomyces sp. NK10958. Synonyms: PA 48153C. CAS No. 151519-02-7. Molecular formula: C19H32O4. Mole weight: 324.5.
Pittosapogenin
Pittosapogenin is a triterpenoid compound. CAS No. 15399-43-6. Molecular formula: C30H50O6. Mole weight: 506.71.