BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Racemomycin B | It is produced by the strain of Str. racemochromogenes 229. It has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture. Synonyms: Streptothricin D; Antibiotic OP 2C; 2-{[(3S)-3-amino-6-{[(3S)-3-amino-6-{[(3S)-3,6-diaminohexanoyl]amino}hexanoyl]amino}hexanoyl]amino}-4-O-carbamoyl-2-deoxy-N-[(3aS,7R,7aS)-7-hydroxy-4-oxooctahydro-2H-imidazo[4,5-c]pyridin-2-ylidene]-beta-D-gulopyranosylamine. Grade: >98%. CAS No. 3776-37-2. Molecular formula: C31H58N12O10. Mole weight: 758.86. |  |
| Racemomycin C | It is produced by the strain of Str. racemochromogenes 229. It has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture. Synonyms: Streptothricin E; Yazumycin C; Antibiotic S 15-1B; 2-((O-(Aminocarbonyl)-2-((3-amino-6-((3,6-diamino-1-oxohexyl)amino)-1-oxohexyl)amino)-2-deoxy-beta-D-gulopyranosyl)amino)-1,3a,5,6,7,7a-hexahydro-7-hydroxy-4H-imidazo(4,5-c)pyridin-4-one; BRN 4286375. CAS No. 3776-38-3. Molecular formula: C25H46N10O9. Mole weight: 630.69. | |
| Racemomycin D | It is produced by the strain of Str. racemochromogenes 229. It has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture. Synonyms: Streptothricin C; Antibiotic OP 2D. CAS No. 3776-36-1. Molecular formula: C37H70N14O11. Mole weight: 887.04. | |
| Racemomycin E | Racemomycin E is an N-glycoside antibiotic produced by various bacteria such as Streptomyces lavendulae. It has anti-gram-positive bacteria, negative bacteria, mycobacteria and anti-fungal activity. Synonyms: Streptothricin B; A 53930C. CAS No. 3484-68-2. Molecular formula: C43H82N16O12. Mole weight: 1015.21. | |
| (Rac)-Saphenamycin | It is a phenazine antibiotic produced by the strain of Str. canarius MG 314-hF8. It has strong effect against gram-positive bacteria and mycobacterium. It inhibits mouse leukemia L5178Y and L1210 cells with ID50 (μg/mL) of 0.15 and 0.6-2.5, respectively (in vitro determination). Synonyms: Saphenamycin; 634600-55-8; (+/-)-Saphenamycin; (Rac)-Saphenamycin; Racemic ssaphenamycin; Saphenamycin, (+/-)-; K9X7806V5B; 1-Phenazinecarboxylic acid, 6-[1-[(2-hydroxy-6-methylbenzoyl)oxy]ethyl]-; 6-[1-(2-hydroxy-6-methylbenzoyl)oxyethyl]phenazine-1-carboxylic acid; 1-Phenazinecarboxylic acid, 6-(1-((2-hydroxy-6-methylbenzoyl)oxy)ethyl)-; A-32256; 83198-27-0; 6-(1-((2-hydroxy-6-methylbenzoyl)oxy)ethyl)phenazine-1-carboxylic acid; 6-{1-[(2-Hydroxy-6-methylbenzoyl)oxy]ethyl}phenazine-1-carboxylic acid; UNII-K9X7806V5B; SCHEMBL11190017; CHEBI:32119; DTXSID301003193; MG 314-HF8; NSC336236; NSC361634; AKOS040747467; NSC-336236; NSC-361634; DA-67402; HY-126924; CS-0108280; Q27114792; 6-[1-(2-hydroxy-6-methyl-benzoyl)oxyethyl]phenazine-1-carboxylic acid; (+)-6-[1-[(2-Hydroxy-6-methylbenzoyl)oxy]ethyl]-1-phenazinecarboxylic acid. CAS No. 634600-55-8. Molecular formula: C23H18N2O5. Mole weight: 402.40. | |
| Radicinin | Radicinin is produced by the strain of Curvularia lunata IAM-18010. It has anti-bacterial effect, but its activity is weak. Synonyms: Stemphylone; NSC 118343; 2,3-Dihydro-3-alpha-hydroxy-2-beta-methyl-7-propenyl-4H,5H-pyrano(4,3-b)pyran-4,5-dione. CAS No. 10088-95-6. Molecular formula: C12H12O5. Mole weight: 236.22. | |
| Rakicidin A | Rakicidin A is originally isolated from Micromonospora sp. R385-2. It has anti-tumor activity in vitro with the IC50 of 40 μg/mL. Molecular formula: C32H54N4O7. Mole weight: 606.79. | |
| Rakicidin B | Rakicidin B is originally isolated from Micromonospora sp. R385-2. It has anti-tumor activity in vitro with the IC50 of 200 μg/mL. Molecular formula: C33H56N4O7. Mole weight: 620.82. | |
| Ramalinolic acid | Ramalinolic acid. Synonyms: Benzoic acid, 2,4-dihydroxy-3-[(2-hydroxy-4-methoxy-6-propylbenzoyl)oxy]-6-pentyl-; 2,4-Dihydroxy-3-(2-hydroxy-4-methoxy-6-propyl-benzoyloxy)-6-pentyl-benzoesaeure; Ramalinolsaeure. CAS No. 552-56-7. Molecular formula: C23H28O8. Mole weight: 432.46. | |
| Ramulosin | It is produced by the strain of Pestalotia ramulosa NRRL 2826. Ramulosin has an antifungal effect and inhibits the germination of fungal meristems. Synonyms: Ramulosine; NSC-112906; Ramulosin, (+)-; (3S,4AR)-8-hydroxy-3-methyl-3,4,4A,5,6, 7-hexahydro-1h-isochromen-1-one. CAS No. 29914-01-0. Molecular formula: C10H14O3. Mole weight: 182.22. | |
| Rancinamycin III | Rancinamycin III is an antibiotic that has antibacterial properties originally isolated from Str. lincolnensis. Synonyms: SCHEMBL16431322. Grade: >97%. CAS No. 60925-60-2. Molecular formula: C7H10O5. Mole weight: 174.15. | |
| (+)-Rangiformic acid | (+)-Rangiformic acid. Synonyms: 1-Methyl (2S,3S)-1,2,3-heptadecanetricarboxylate. CAS No. 29227-63-2. Molecular formula: C21H38O6. Mole weight: 386.52. | |
| Rasfonin | Rasfonin is a fungal metabolite that has been found in Talaromyces sp. 3656-A1. It is a Ras-dependent apoptosis inducer that induces apoptosis in Ras-dependent cells such as Ba/F3-V12 cells. Synonyms: (-)-Rasfonin; (2E,4E,6S)-8-hydroxy-6-(hydroxymethyl)-4-methyl-2,4-octadienoic acid, (2R,3R)-3,6-dihydro-6-oxo-2-[(1S,3R,5E)-1,3,5-trimethyl-5-hepten-1-yl]-2H-pyran-3-yl ester. Grade: >95%. CAS No. 303156-68-5. Molecular formula: C25H38O6. Mole weight: 434.56. | |
| Reblastatin | Reblastatin is an Ansa antibiotic produced by Streptomyces hygroscopicus subsp. hygroscopicus SANK 61995 and is a reduction product of Geldanamycin. It is a cell cycle inhibitor that can inhibit cell proliferation. The IC50 for human mesenchymal lymphoma U-93 is 0.43 μg/mL, and the reference geldanamycin is 0.0011 μg/mL. Molecular formula: C29H44N2O8. Mole weight: 548.67. | |
| Reductiline | Reductiline is a pyrrole derivative produced by Streptomyces orientalis Y-1336. It has anti-Gram-positive bacteria and weak anti-fungal, virus and tumor activity. Synonyms: 2-Propenamide, N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-3-[1-[3-(methylthio)propyl]-1H-pyrrol-3-yl]-, (E)-; Antibiotic AIS 2M3. CAS No. 85145-25-1. Molecular formula: C16H20N2O3S. Mole weight: 320.41. | |
| RES-1149-1 | RES-1149-1 is an endothelin type B receptor antagonist produced by Aspergillus sp. RE-1149. It selectively inhibits the ET-1 binding to endothelin type B receptor with IC50 value of 1.5 μmol/L. Molecular formula: C23H30O5. Mole weight: 386.5. | |
| RES-1149-2 | RES-1149-2 is an endothelin type B receptor antagonist produced by Aspergillus sp. RE-1149. It selectively inhibits the ET-1 binding to endothelin type B receptor with IC50 value of 20 μmol/L. Molecular formula: C23H30O5. Mole weight: 386.5. | |
| RES-1214-1 | RES-1214-1 is an endothelin type A receptor antagonist produced by Pestalotiopsis sp. RE-1214. It selectively inhibits the ET-1 binding to endothelin type A receptor with IC50 value of 1.5 μmol/L. Molecular formula: C17H16O8. Mole weight: 348.3. | |
| RES-1214-2 | RES-1214-2 is an endothelin type A receptor antagonist produced by Pestalotiopsis sp. RE-1214. It selectively inhibits the ET-1 binding to endothelin type A receptor with IC50 value of 20 μmol/L. Molecular formula: C17H15ClO8. Mole weight: 382.7. | |
| RES-701-2 | RES-701-2 is an endothelin type B receptor antagonist produced by Streptomyces sp. RE-701. It selectively inhibits the ET-1 binding to endothelin type B receptor. Molecular formula: C103H115N23O24. Mole weight: 2059.15. | |
| Reserpiline | Reserpiline is an indole alkaloid that has been found in R. tetraphylla. It is an antipsychotic, antiparasitic and hypotensive agent. Synonyms: Methyl (3beta,19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate; Elliptamine; Reserpilin; (-)-Reserpiline; (4S,4aS,13bR,14aS)-4a,5,7,8,13,13b,14,14a-octahydro-10,11-dimethoxy-4-methyl-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylic acid, methyl ester; methyl (4S,4aS,13bR,14aS)-10,11-dimethoxy-4-methyl-4a,5,7,8,13,13b,14,14a-octahydro-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylate. Grade: >95% by HPLC. CAS No. 131-02-2. Molecular formula: C23H28N2O5. Mole weight: 412.48. | |
| Resinone | Resinone is a bioactive chemical. Synonyms: Lup-20(29)-en-3-one, 16-hydroxy-, (16β)-; 16-Hydroxylup-20(29)-en-3-one; Lup-20(29)-en-3-one, 16-hydroxy-, (16beta)-; (1R,3aS,4S,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-4-hydroxy-3a,5a,5b,8,8,11a-hexamethyl-1-(prop-1-en-2-yl)icosahydro-9H-cyclopenta[a]chrysen-9-one; 16β-Hydroxylup-20(29)-en-3-one. Grade: >98%. CAS No. 43043-12-5. Molecular formula: C30H48O2. Mole weight: 440.70. | |
| Resomycin A | It is produced by the strain of Streptomyces sp. GW71/2497. Resomycin A showed activity of anti-staphylococcus aureus, Escherichia coli and Streptomyces green, with MIC of about 20 μg/mL. Molecular formula: C21H18O7. Mole weight: 382.36. | |
| Resomycin B | It is produced by the strain of Streptomyces sp. GW71/2497. Resomycin B showed activity of anti-staphylococcus aureus, Escherichia coli and Streptomyces green, with MIC of about 20 μg/mL. Molecular formula: C21H16O6. Mole weight: 364.35. | |
| Resomycin C | It is produced by the strain of Streptomyces sp. GW71/2497. Resomycin C showed activity of anti-staphylococcus aureus, Escherichia coli and Streptomyces green, with MIC of about 20 μg/mL. Molecular formula: C21H14O6. Mole weight: 362.33. | |
| Resorcinomycin B | Resorcinomycin B is originally isolated from Streptoverticillum roseoverticillatum. Synonyms: N-(alpha-Guanidino-3,5-dihydroxy-4-ethylphenylacetyl)glycine. CAS No. 100234-69-3. Molecular formula: C13H18N4O5. Mole weight: 310.31. | |
| Resormycin | It is originally isolated from Str. platensis MJ953-SF5. It has a strong herbicide effect, especially on the seeds of dicotyledonous plants. Resormycin also has anti-fungal action, resisting some plant pathogenic fungi, but not resisting bacteria and yeast. Molecular formula: C21H31ClN4O7. Mole weight: 486.95. | |
| Resorthiomycin | It is produced by the strain of Str. collinus 45H6 and it can inhibit L5178Y of leukemia cells in vitro. Synonyms: 6-Acetyl-4-(3-hydroxybutyl)-2-methyl-5-methylthioresorcinol. CAS No. 126651-92-1. Molecular formula: C14H20O4S. Mole weight: 284.37. | |
| Respinomycin A1 | Respinomycin A1 is produced by the strain of Str. xanthocidicus RK-483 and it causes the differentiation of leukemic K-562 cells. Synonyms: 13-[(6-Deoxy-3-C-methyl-2-O-methylhexopyranosyl)oxy]-23-(dimethylamino)-11,15,22-trihydroxy-12-methoxy-1,11-dimethyl-6,17-dioxo-20,25-dioxahexacyclo[19.3.1.02,19.05,18.07,16.09,14]pentacosa-2, 4,7(16),8,14,18-hexaen-24-yl 3-amino-2,3,6-trideoxy-4-O-(6-deoxy-3-C-methyl-2-O-methylhexopyranosyl)-3-methylhexopyranoside. Grade: >99%. CAS No. 138843-19-3. Molecular formula: C51H72N2O20. Mole weight: 1033.12. | |
| Respinomycin A2 | Respinomycin A2 is produced by the strain of Str. xanthocidicus RK-483 and it causes the differentiation of leukemic K-562 cells. Synonyms: 2,6-Epoxy-2H-naphthaceno(1,2-b)oxocin-9,16-dione, 3,4,5,6,11,12,13,14-octahydro-5-((3-amino-2,3,6-trideoxy-4-O-(6-deoxy-3-C-methyl-2-O-methyl-alpha-mannopyranosyl)-3-C-methyl-beta-ribo-hexopyranosyl)oxy)-6,12-dimethyl-4-(dimethylamino)-13-methoxy-3,12,15-trihydroxy-, (2-alpha,3-beta,4-alpha,5-alpha,6-alpha,12-beta,13-alpha)-(+)-. CAS No. 151233-04-4. Molecular formula: C43H58N2O15. Mole weight: 842.92. | |
| Respirantin | Respirantin. Synonyms: Cyclodepsipeptide 1. CAS No. 149598-67-4. Molecular formula: C37H53N3O13. Mole weight: 747.83. | |
| Reticulol | An isocoumarin metabolite produced by selected species of streptomyces. It is a potent inhibitor of cyclic nucleotide phosphodiesterase. It also causes dose-dependent inhibition of lung metastasis in the B16F10 melanoma model. Synonyms: 6,8-Dihydroxy-7-methoxy-3-methylisocoumarin; 6,8-Dihydroxy-7-methoxy-3-methyl-1H-2-benzopyran-1-one; K 251-1; NSC 294978. Grade: >95% by HPLC. CAS No. 26246-41-3. Molecular formula: C11H10O5. Mole weight: 222.19. | |
| Reumycin | It is originally isolated from Act. sp. Reumycin is toxic to Airy carcinoma, sarcoma-180, sarcoma-37, lymphosarcoma and other tumor cells. Synonyms: Reumitsin; Rheumygin; 1-demethyltoxoflavin; NSC 99733; 6-Methylpyrimido(5,4-e)-as-triazine-5,7(1H,6H)-dione. CAS No. 5016-18-2. Molecular formula: C6H5N5O2. Mole weight: 179.14. | |
| Reveromycin A | The dominant analogue of complex of spiroketals isolated from streptomyces sp. It is an inhibitor of the mitogenic activity of EGF and a G1 phase cell cycle inhibitor. It selectively inhibits isoleucyl-trna synthetase. It has anti-proliferation effect on human cell lines KB and K562, and has potent antifungal activity. Synonyms: (-)-Reveromycin A; [2S-[2α(1E,3E),3β,6α[8S*(2E,4E,6R*,7R*,8E),9R*]]]-butanedioic acid mono[3-butyl-8-(9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrienyl)-2-(4-carboxy-3-methyl-1,3-butadienyl)-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] Ester; Butanedioic Acid Mono[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrienyl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadienyl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] Ester. Grade: >99% by HPLC. CAS No. 134615-37-5. Molecular formula: C36H52O11. Mole weight: 660.79. | |
| Reveromycin D | Reveromycin D is a bacterial metabolite isolated from Streptomyces. It inhibits EGF-induced mitotic activity in Balb/MK cells and has pH-dependent antifungal activity against Candida albicans. Grade: >95% by HPLC. CAS No. 144860-70-8. Molecular formula: C37H54O11. Mole weight: 674.82. | |
| Rhizonic acid | Rhizonic acid. Synonyms: Benzoic acid, 2-hydroxy-4-methoxy-3,6-dimethyl-; Rhizoninsaure; 6-Oxy-4-methoxy-2,5-dimethyl-benzoesaeure. Grade: ≥97%. CAS No. 479-26-5. Molecular formula: C10H12O4. Mole weight: 196.20. | |
| Rhodirubin A | It is produced by the strain of Str. sp. ME505-HE1. Rhodirubin A has a strong anti-gram-positive bacteria effect, and also has an effect on Mycobacterium. It can also prolong the survival time of mice inoculated with leukemia L-1210. Synonyms: 1-Hydroxy-MA-144-N1; MA144 N2; 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,10-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-4-0-(2,6-dideoxy-4-O-((2S-(2-alpha,5-beta,6-beta))-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-. CAS No. 64253-73-2. Molecular formula: C42H55NO16. Mole weight: 829.88. | |
| Rhodirubin B | It is produced by the strain of Str. sp. ME505-HE1. Rhodirubin B has a strong anti-gram-positive bacteria effect, and also has an effect on Mycobacterium. It can also prolong the survival time of mice inoculated with leukemia L-1210. Synonyms: 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-2-ethyl-2,5,7,10-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-4-O-((2S-(2-alpha,5-beta(2R*,5R*,6R*),6-beta))-tetrahydro-6-methyl-5-((tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)oxy)-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-. CAS No. 64502-82-5. Molecular formula: C42H55NO15. Mole weight: 813.88. | |
| Rhodomycin | Rhodomycin are a family of antibiotics produced by a red-pigmented mutant of Streptomyces griseus. They possess anti-gram-positive bacteria, anti-gram-negative bacteria and antifungal properties. Synonyms: Epsilon-Rhodomycin. CAS No. 1401-16-7. | |
| Rhodomycin A | Rhodomycin A is originally isolated from Str. purpurascens 340. It has the activity of anti-gram-positive bacteria and weak effect on anti-gram-negative bacteria and fungi. Synonyms: beta-Rhodomycin II; NSC-136044; 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-7,10-bis((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, (7R,8R,10S)-. CAS No. 23666-50-4. Molecular formula: C36H48N2O12. Mole weight: 700.77. | |
| Rhodomycin B | Rhodomycin B is originally isolated from Str. purpurascens 340. It has the activity of anti-gram-positive bacteria and weak effect on anti-gram-negative bacteria and fungi. Synonyms: beta-Rhodomycin I; Betaclamycin T; BRN 0073612. Grade: ≥95%. CAS No. 1404-52-0. Molecular formula: C28H33NO10. Mole weight: 543.56. | |
| Rhodopeptin C1 | Rhodopeptin C1 is a cyclic tetrapeptide originally isolated from Rhodococcus sp. Mer-N1033. It has anti-candida and cryptococcus neoformant activities, and the MIC (μg/mL) was 1.25~2.5 and 0.63~1.25, respectively. Synonyms: (3S,6S)-6-(3-aminopropyl)-3-isopropyl-13-(7-methylnonyl)-1,4,7,10-tetrazacyclotridecane-2,5,8,11-tetrone. Molecular formula: C25H47N5O4. Mole weight: 481.67. | |
| Rhodopeptin C2 | Rhodopeptin C2 is a cyclic tetrapeptide originally isolated from Rhodococcus sp. Mer-N1033. It has anti-candida and cryptococcus neoformant activities, and the MIC (μg/mL) was 1.25~2.5 and 0.63~1.25, respectively. Synonyms: (3S,6S)-6-(3-aminopropyl)-13-(7-methylnonyl)-3-sec-butyl-1,4,7,10-tetrazacyclotridecane-2,5,8,11-tetrone. Molecular formula: C26H49N5O4. Mole weight: 495.70. | |
| Rhodopeptin C3 | Rhodopeptin C3 is a cyclic tetrapeptide originally isolated from Rhodococcus sp. Mer-N1033. It has anti-candida and cryptococcus neoformant activities, and the MIC (μg/mL) was 1.25~2.5 and 0.63~1.25, respectively. Synonyms: (3S,6S)-6-(3-aminopropyl)-3-isopropyl-13-(9-methyldecyl)-1,4,7,10-tetrazacyclotridecane-2,5,8,11-tetrone. Molecular formula: C26H49N5O4. Mole weight: 495.70. | |
| Rifamycin L | Rifamycin L is produced by the strain of Amycolatopsis mediterranei ME/83. It has the antibacterial action of rifamycin. Synonyms: Rifamycin, 4-(hydroxyacetate). Grade: >98%. CAS No. 26117-02-2. Molecular formula: C39H49NO14. Mole weight: 755.80. | |
| Rifamycin W | Rifamycin W is originally isolated from Amycolatopsis mediterranei ME/83. It has anti-gram-positive bacterial activity. CAS No. 53904-81-7. Molecular formula: C35H45NO11. Mole weight: 655.73. | |
| Rimocidin | It is originally isolated from Str. rimosus and it has antifungal and protozoan effects. Synonyms: Rimocidine. Grade: >98%. CAS No. 1393-12-0. Molecular formula: C39H61NO14. Mole weight: 767.90. | |
| Ripromycin | Ripromycin is produced by the strain of Streptomyces sp Tu 6239. It has moderate anti-gram-positive bacterial activity, but not anti-gram-negative bacteria or fungi. It inhibited the proliferation of HM02 and MCF cells with IC50 of 1.6 and 2.0 μg/mL, respectively. Molecular formula: C30H40N2O6. Mole weight: 524.65. | |
| RIT D-2214 | RIT D-2214 is a penicillin antibiotic produced by Acremonium chrysogenum. It is active against gram-positive and gram-negative bacteria. Molecular formula: C13H19N3O6S2. Mole weight: 377.4. | |
| RK-1009 | RK-1009 is an antibiotic produced by Streptomyces sp. RK-1009. Synonyms: RK 1009; RK1009. Molecular formula: C45H64N2O10. Mole weight: 793. | |
| RK-286C | RK-286C is a protein kinase C (PKC) inhibitor produced by Streptomyces sp. RK-286. It inhibits PKC activity with IC50 of 3.0 μmol/L, as well as suppresses platelet aggregation induced by collagen and ADP. Synonyms: RK 286C; RK286C. CAS No. 126572-73-4. Molecular formula: C27H23N3O4. Mole weight: 453.5. | |
| RK-397 | RK-397 is a macrolide antibiotic produced by Streptomyces sp. 87-397. It is cytotoxic against human leukemia HL-60 and K-562 cells at a concentration of 50 μg/mL. It induces bleb-formation on K-562 cells at the concentrations over 0.05 μg/mL. Synonyms: RK 397; RK397; 14-demethyl-mycoticin; 14-demethylmycoticina. CAS No. 154396-73-3. Molecular formula: C35H56O10. Mole weight: 636.8. | |
| RK-682 hemicalcium | It is a dimeric calcium complex of the major analogue of tetronic acid complex isolated from streptomyces. It inhibits protein tyrosine phosphatases, phospoholipase A2, heparinase and HIV-1 protease. Synonyms: 332131-32-5; TAN 1364B, CI 010; calcium; (2R)-4-hexadecanoyl-2-(hydroxymethyl)-5-oxo-2H-furan-3-olate; RK-682 (calcium salt); Calcium (R)-2-(hydroxymethyl)-5-oxo-4-palmitoyl-2,5-dihydrofuran-3-olate. Grade: >95% by HPLC. CAS No. 332131-32-5. Molecular formula: C18H14ClF4NO4. Mole weight: 419.8. | |
| Ro 09-1679 | Ro 09-1679 is a thrombin inhibitor produced by Mortierella alpina NR6773. It inhibits thrombin, Factor Xa, trypsin and papain with IC50 values of 33.6, 3.3, 0.04 and 0.0346 μmol/L. Synonyms: L-Leucinamide, N2-(3-carboxy-1-oxo-2-propenyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-, (S-(E))-. CAS No. 141426-89-3. Molecular formula: C22H39N9O6. Mole weight: 525.61. | |
| Robustol methyl ether | Robustol methyl ether. CAS No. 27825-39-4. Molecular formula: C29H42O4. Mole weight: 454.64. | |
| Roccellaric acid | Roccellaric acid. Synonyms: 3-Furancarboxylic acid, tetrahydro-4-methyl-5-oxo-2-tridecyl-, [2R-(2α,3β,4α)]-; (2R,3S,4S)-Tetrahydro-4-methyl-5-oxo-2-tridecyl-3-furancarboxylic acid; (+)-Roccellaric acid; Dihydroneoprotolichesteric acid; Nephromopsinic acid (-). CAS No. 19464-85-8. Molecular formula: C19H34O4. Mole weight: 326.47. | |
| Rodaplutin | Rodaplutin is a peptidylnucleoside antibiotic produced by Streptomyces sp. Sch 36605. It exhibits anti-inflammatory and moderate antibacterial activity. Synonyms: Sch-36605; Sch 36605. CAS No. 108351-49-1. Molecular formula: C24H39N9O7. Mole weight: 565.6. | |
| Roquefortine C | A potent tremorgenic mycotoxin originally isolated from penicillium roqueforti. It is a penicillium commercially used to ripen blue-veined cheese. Synonyms: Roquefortine; NSC 292134; (3E,5aS,10bR,11aS)-10b-(1,1-Dimethyl-2-propen-1-yl)-6,10b,11,11a-tetrahydro-3-(1H-imidazol-5-ylmethylene)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione; (-)-Roquefortine C; Roquefortin. Grade: >99% by HPLC. CAS No. 58735-64-1. Molecular formula: C22H23N5O2. Mole weight: 389.45. | |
| Roquefortine E | An analogue of roquefortine C, containing an additional isoprenyl unit on the imidazole similar to phenylhistin. Roquefortine E is an antimitotic agent. It is a selective, albeit weakly active, antitumour agent. Grade: >95% by HPLC. CAS No. 871982-52-4. Molecular formula: C27H31N5O2. Mole weight: 457.57. | |
| Roridin C | Roridin C is a fungal sesquiterpene derived from Myrothecium roridum S-1135 (NRRL 3005). Synonyms: Trichodermol; BRN 1287601; 12,13-Epoxytrichothec-9-en-4-beta-ol; (2S,2'R,4'R,5'S,5a'R,9a'R)-5',5a',8'-trimethyl-2',3',4',5',5a',6',7',9a'-octahydrospiro[oxirane-2,10'-[2,5]methanobenzo[b]oxepin]-4'-ol. Grade: >98%. CAS No. 2198-93-8. Molecular formula: C15H22O3. Mole weight: 250.33. | |
| Roridin D | Roridin D is originally isolated from Myrothecium roridum S-1135 (NRRL 3005). Synonyms: Roridin-D; 7'-Deoxo-2'-deoxy-2',3'-epoxy-7'-(1-hydroxyethyl)verrucarin A; Verrucarin A, 7'-deoxo-2'-deoxy-2',3'-epoxy-7'-(1-hydroxyethyl)-; NSC-374338. CAS No. 14682-29-2. Molecular formula: C29H38O9. Mole weight: 530.61. | |
| Roridin E | Roridin E is a macrocyclic trichothecene mycotoxin that has been found in M. verrucaria. It exhibits anticancer activity against various cancer cell lines. Synonyms: Verrucarin A, 2',3'-didehydro-7'-deoxo-2'-deoxy-7'-((1R)-1-hydroxyethyl)-, (2'E,7'R)-. Grade: ≥95% by HPLC. CAS No. 16891-85-3. Molecular formula: C29H38O8. Mole weight: 514.61. | |
| Roridine H | Roridin E is originally isolated from Myrothecium roridum S-1135 (NRRL 3005). Synonyms: CL-72-VB-s; CL-72-VB-2; NSC 274540; Verrucarin A, 2',3'-didehydro-7'-deoxo-2'-deoxy-7',5'-(ethylideneoxy)-. CAS No. 29953-50-2. Molecular formula: C29H36O8. Mole weight: 512.59. | |
| Roridin J | Roridin J is originally isolated from Myrothecium roridum S-1135 (NRRL 3005) and it has anti-leukemia effect in mice. Synonyms: NSC-319082. CAS No. 74072-83-6. Molecular formula: C29H36O9. Mole weight: 528.59. | |
| Roridin L2 | Roridin L2 is originally isolated from M. roridum var. and it has antibacterial and antitumor effects. Synonyms: (2S,2'R,4'R,5'S,5a'R,9a'R)-5a'-(hydroxymethyl)-5',8'-dimethyl-2',3',4',5',5a',6',7',9a'-octahydrospiro[oxirane-2,10'-[2,5]methanobenzo[b]oxepin]-4'-yl (2Z,4E)-7-hydroxy-6-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethoxy)octa-2,4-dienoate. Grade: >70%. CAS No. 85124-22-7. Molecular formula: C29H38O9. Mole weight: 530.61. | |
| Roselipin 1A | Roselipin 1A is produced by the strain of Gliocladium roseum KF-1040. It inhibited the DGAT of rat hepatic microcosm with IC50 of 15~22 μmol/L. CAS No. 232258-17-2. Molecular formula: C40H72O14. Mole weight: 776.99. | |
| Roselipin 1B | Roselipin 1B is produced by the strain of Gliocladium roseum KF-1040. It inhibited the DGAT of rat hepatic microcosm with IC50 of 15~22 μmol/L. CAS No. 232258-18-3. Molecular formula: C40H72O14. Mole weight: 776.99. | |
| Roselipin 2A | Roselipin 2A is produced by the strain of Gliocladium roseum KF-1040. It inhibited the DGAT of rat hepatic microcosm with IC50 of 15~22 μmol/L. Synonyms: Roselipin-2A. CAS No. 232258-26-3. Molecular formula: C42H74O15. Mole weight: 819.03. | |
| Roselipin 2B | Roselipin 2B is produced by the strain of Gliocladium roseum KF-1040. It inhibited the DGAT of rat hepatic microcosm with IC50 of 15~22 μmol/L. Synonyms: Roselipin-2B. CAS No. 232258-27-4. Molecular formula: C42H74O15. Mole weight: 819.03. | |
| Roseocardin | A new cyclodepsipeptide, designated roseocardin, was isolated from the culture broth of Trichothecium roseum TT103. Roseocardin as well as the other cyclodepsipeptides were shown to produce positive inotropic effects on rat heart muscles. Molecular formula: C31H53N5O7. Mole weight: 607.78. | |
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