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| Product | Description | |
|---|---|---|
| Scytalol B | It is produced by the strain of Scytalidium sp. 36-93. Synonyms: 10H-Naphtho[2,3-c]pyran-10-one,1,3,4,4a,5,10a-hexahydro-5,9-dihydroxy-3,7-dimethoxy-3-methyl-, (3R,4aS,5S,10aR)-rel-(+)-. CAS No. 208183-20-4. Molecular formula: C16H20O6. Mole weight: 308.33. |  |
| Scytalol C | It is produced by the strain of Scytalidium sp. 36-93. Synonyms: Naphtho[1,2-b]furan-5(4H)-one,2,3,3a,9btetrahydro-6-hydroxy-2,8-dimethoxy-4-(methoxymethylene)-2-methyl-, (2R,3aR,4E,9bR)-rel-(-)-. CAS No. 208183-22-6. Molecular formula: C17H20O6. Mole weight: 320.34. | |
| Scytalol D | It is produced by the strain of Scytalidium sp. 36-93. It selectively inhibits biosynthesis of dihydroxynaphthalene melanin in Lachnellula sp. A32-89, but does not inhibit the growth of the strain. Synonyms: 1(2H)-Naphthalenone, 3,4-dihydro-4,8-dihydroxy-6-methoxy-3-(2-oxopropyl)-, (3R,4R)-rel-(+)-. CAS No. 208183-24-8. Molecular formula: C14H16O5. Mole weight: 264.27. | |
| (S)-Dihydroaeruginoic acid | It is a simple aromatic siderophore produced by several species of pseudomonas. It exhibits antibacterial, antifungal and antitumor activity. Synonyms: (4S)-4,5-Dihydro-2-(2-hydroxyphenyl)-4-thiazolecarboxylic Acid; CGP 52547; (S)-4,5-Dihydro-2-(2-hydroxyphenyl)-4-thiazolecarboxylic Acid; (+)-(S)-Dihydroaeruginoic Acid; (+)-Dihydroaeruginoic acid; 4-Thiazolecarboxylic acid, 4,5-dihydro-2-(2-hydroxyphenyl)-, (S)-; 4-Thiazolecarboxylic acid, 4,5-dihydro-2-(2-hydroxyphenyl)-, (4S)-; (S)-2-(2-Hydroxyphenyl)-4,5-dihydrothiazole-4-carboxylic acid; (4S)-Dihydroaeruginoic acid. Grade: >98% by HPLC. CAS No. 143209-04-5. Molecular formula: C10H9NO3S. Mole weight: 223.25. | |
| Seitomycin | It is an anthraquinone antibiotic produced by the strain of Streptomyces sp. GW 19/1251. It has moderate activity against Gram-positive bacteria such as Staphylococcus aureus and Bacillus subtilis, Gram-negative bacteria such as Escherichia coli and green Streptomyces chlorophyllus. Synonyms: Benz[a]anthracene-7,12-dione, 1,2,3,4-tetrahydro-1,3,11-trihydroxy-8-methoxy-3-methyl-. CAS No. 630391-05-8. Molecular formula: C20H18O6. Mole weight: 354.35. | |
| Sekikaic acid | Sekikaic acid. Synonyms: Benzoic acid, 2-hydroxy-3-[(2-hydroxy-4-methoxy-6-propylbenzoyl)oxy]-4-methoxy-6-propyl-; Sekikasaeure; 6-Hydroxy-5-(6-hydroxy-4-methoxy-2-propyl)-4-methoxy-2-propyl-benzoesaeure; 6-Oxy-4-methoxy-5-(6-oxy-4-methoxy-2-propyl-benzoyloxy)-2-propyl-benzoesaeure. CAS No. 607-11-4. Molecular formula: C22H26O8. Mole weight: 418.44. | |
| Seldomycin 1 | Seldomycin 1 is an aminoglycoside antibiotic produced by the strain of Str. hofunensis nor. sp. It has a broad spectrum of antimicrobial activity, and Seldomycin F5 has the strongest antimicrobial activity. It is cross-resistant to E. coli with aminoglycoside antibiotic passivation enzyme (such as APH (3')-1, APH(3')-II, AAC(6'), AAC(2)). ED50 is greater than 1000 mg/kg (abdominal infection in mice, intravenous administration). Synonyms: Antibiotic XK 88-1; XK 88-1; Seldomycin factor 1; D-Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2-amino-2-deoxy-alpha-D-xylopyranosyl-(1-6))-2-deoxy-; 4-O-(2-Amino-2-deoxy-α-D-glucopyranosyl)-6-O-(2-amino-2-deoxy-α-D-xylopyranosyl)-2-deoxy-D-streptamine. CAS No. 56276-04-1. Molecular formula: C17H34N4O10. Mole weight: 454.47. | |
| Seldomycin 2 | Seldomycin 2 is an aminoglycoside antibiotic produced by the strain of Str. hofunensis nor. sp. It has a broad spectrum of antimicrobial activity, and Seldomycin F5 has the strongest antimicrobial activity. It is cross-resistant to E. coli with aminoglycoside antibiotic passivation enzyme (such as APH (3')-1, APH(3')-II, AAC(6'), AAC(2)). ED50 is 36-60 mg/kg (abdominal infection in mice, intravenous administration). Synonyms: 4'-Deoxyneamine; Seldomycin factor 2; Antibiotic XK 88-2; XK 88-2; D-Streptamine, 2-deoxy-4-O-(2,6-diamino-2,4,6-trideoxy-alpha-D-xylo-hexopyranosyl)-. CAS No. 54333-78-7. Molecular formula: C12H26N4O5. Mole weight: 306.36. | |
| Seldomycin 3 | Seldomycin 3 is an aminoglycoside antibiotic produced by the strain of Str. hofunensis nor. sp. It has a broad spectrum of antimicrobial activity, and Seldomycin F5 has the strongest antimicrobial activity. It is cross-resistant to E. coli with aminoglycoside antibiotic passivation enzyme (such as APH (3')-1, APH(3')-II, AAC(6'), AAC(2)). Synonyms: 6-O-(2-Amino-2-deoxy-α-D-xylopyranosyl)-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine; Seldomycin factor-3; Xk-88-3; Antibiotic XK-88-3. CAS No. 56276-05-2. Molecular formula: C17H35N5O9. Mole weight: 453.49. | |
| Seldomycin 5 | Seldomycin 5 is an aminoglycoside antibiotic produced by the strain of Str. hofunensis nor. sp. It has a broad spectrum of antimicrobial activity, and Seldomycin F5 has the strongest antimicrobial activity. It is cross-resistant to E. coli with aminoglycoside antibiotic passivation enzyme (such as APH (3')-1, APH(3')-II, AAC(6'), AAC(2)). ED50 is 7.5-15 mg/kg (abdominal infection in mice, intravenous administration). Synonyms: 6-O-(2,3-Diamino-4-O-methyl-2,3-dideoxy-α-D-xylopyranosyl)-4-O-(2,6-diamino-2,4,6-trideoxy-α-D-xylo-hexopyranosyl)-2-deoxy-D-streptamine; Seldomycin factor-5; D-Streptamine, O-2,3-diamino-2,3-dideoxy-4-o-methyl-alpha-D-xylopyranosyl-(1-6)-o-(2,6-diamino-2,4,6-trideoxy-alpha-D-xylo-hexopyranosyl-(1-4))-2-deoxy-; Xk-88-5; Antibiotic XK-88-5. CAS No. 56276-26-7. Molecular formula: C18H38N6O7. Mole weight: 450.53. | |
| Senfolomycin A | It is produced by the strain of Str. ochrosporus NRRL 3146. It has the effect of anti-Gram-positive bacteria and mycobacterium, and also has the effect of anti-Staphylococcus aureus resistant to penicillin, streptomycin, neomycin, macrolide antibiotics. It also has weaker effect of anti-Gram-negative bacteria. Synonyms: Paulomycin E; 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-(4-C-acetyl-2,6-dideoxy-3-O-methyl-a-L-xylo-hexopyranosyl)-4-O-[(2Z)-2-isothiocyanato-1-oxo-2-butenyl]-b-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-; Antibiotic LL RA 6950BA. CAS No. 11017-36-0. Molecular formula: C29H36N2O16S. Mole weight: 700.66. | |
| Senfolomycin B | It is produced by the strain of Str. ochrosporus NRRL 3146. It has the effect of anti-Gram-positive bacteria and mycobacterium, and also has the effect of anti-Staphylococcus aureus resistant to penicillin, streptomycin, neomycin, macrolide antibiotics. It also has weaker effect of anti-Gram-negative bacteria. Synonyms: Paulomycin F; 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-[2,6-dideoxy-4-C-(1-hydroxyethyl)-3-O-methyl-α-L-xylo-hexopyranosyl]-4-O-[(2Z)-2-isothiocyanato-1-oxo-2-buten-1-yl]-β-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-; Antibiotic LL RA 6950BB. CAS No. 11031-56-4. Molecular formula: C29H38N2O16S. Mole weight: 702.68. | |
| Septamycin | It is a polyether antibiotic produced by the strain of Str. hygroscopicus NRRL 5678. It has anti-bacterial effect and is also effective against some drug-resistant bacteria (Resistance to penicillin, aminoglycoside antibiotics, etc). Synonyms: Antibiotic A-28695A; 2H-Pyran-2-acetic acid, 6-[[(2R,3R,4R,5S,7S,9R,10R)-3,9-dimethoxy-2,4,10-trimethyl-2-[(2S,2'R,5R,5'R)-octahydro-5'-[(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-1,6-dioxaspiro[4.5]dec-7-yl]methyl]tetrahydro-2-hydroxy-4-methoxy-a,3,5-trimethyl-5-[[(2S,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]oxy]-,(aR,2S,3S,4S,5S,6S)-; 2H-Pyran-2-acetic acid, 6-[[3,9-dimethoxy-2,4,10-trimethyl-2-[octahydro-5'-(tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl)[2,2'-bifuran]-5-yl]-1,6-dioxaspiro[4.5]dec-7-yl]methyl]tetrahydro-2-hydroxy-4-methoxy-a,3,5-trimethyl-5-[(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy]-, [2S-[2a,2(S*),3a,4b,5a(2R*,5R*,6S*),6b[2S*[2R*,2'S*,5S*,5'S*(2R*,3R*,5S*,6R*)],3S*,4S*,5R*,7R*,9S*,10S*]]]-. CAS No. 54927-63-8. Molecular formula: C48H82O16. Mole weight: 915.16. | |
| Septamycin Sodium salt | It is a polyether antibiotic produced by the strain of Str. hygroscopicus NRRL 5678. It has anti-bacterial effect and is also effective against some drug-resistant bacteria (Resistance to penicillin, aminoglycoside antibiotics, etc). Synonyms: Septamycin, monosodium salt. CAS No. 55924-40-8. Molecular formula: C48H81NaO16. Mole weight: 937.13. | |
| Serratamolide | It is a depsipeptide antibiotic produced by the strain of Serratia marcescens HY-3. It has anti-gram-positive bacteria, mycobacteria and fungi activity, but the activity is weak. Synonyms: Serrawettin W1; serratamolide A; NSC 81415; Cyclic(D-beta-hydroxydecanoyl-L-seryl-D-beta-hydroxydecanoyl-L-seryl). CAS No. 5285-25-6. Molecular formula: C26H46N2O8. Mole weight: 514.65. | |
| Seryl-arginine | Seryl-arginine is a dipeptide composed of serine and arginase. Synonyms: Ser-Arg; L-Seryl-L-arginine. CAS No. 13261-11-5. Molecular formula: C9H19N5O4. Mole weight: 261.28. | |
| Seryl-isoleucine | Seryl-isoleucine is a dipeptide composed of serine and isoleucine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Isoleucine, L-seryl-; Ser-Ile; H-SI-OH; L-seryl-L-isoleucine; L-Ser-L-Ile. Grade: ≥95%. CAS No. 91086-51-0. Molecular formula: C9H18N2O4. Mole weight: 218.25. | |
| Seryl-lysine | Seryl-lysine is a dipeptide composed of serine and lysine. Synonyms: L-Serinyl-L-lysine; seryl lysine. CAS No. 22677-61-8. Molecular formula: C9H19N3O4. Mole weight: 233.26. | |
| Seryl-threonine | Seryl-threonine is a dipeptide composed of serine and threonine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Threonine, L-seryl-; L-seryl-L-threonine; Ser-Thr; Serinylthreonine; ST dipeptide; L-Ser-L-Thr. Grade: ≥95%. CAS No. 61043-85-4. Molecular formula: C7H14N2O5. Mole weight: 206.20. | |
| Seryl-tryptophan | Seryl-tryptophan is a dipeptide composed of serine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: Ser-Trp-OH; Ser-Trp; L-Tryptophan, L-seryl-; Seryltryptophan; S-W Dipeptide; Serine Tryptophan dipeptide; L-seryl-L-tryptophan; H-SW-OH. Grade: ≥95%. CAS No. 94421-70-2. Molecular formula: C14H17N3O4. Mole weight: 291.30. | |
| Seryl-Valine | Seryl-Valine is a dipeptide composed of serine and valine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: H-SV-OH; L-seryl-L-valine; L-Valine, L-seryl-; Serinyl-Valine; L-Ser-L-Val. Grade: ≥95%. CAS No. 51782-06-0. Molecular formula: C8H16N2O4. Mole weight: 204.22. | |
| Setosusin | Setosusin is a meroterpenoid fungal metabolite originally isolated from corynascus setosus. It reduces neurotoxicity induced by amyloid-β (Aβ) aggregates in PC12 cells (EC50 = 112.6 μM). In vivo, setosusin (30 mg/kg) induces tremors in mice. Grade: ≥99%. CAS No. 182926-45-0. Molecular formula: C29H38O8. Mole weight: 514.61. | |
| SF-1623 | SF-1623 is a cephamycin antibiotic produced by the the fermentation of Streptomyces chartreusis. It is active against gram-negative bacteria. Synonyms: SF 1623. CAS No. 56487-86-6. Molecular formula: C15H21N3O10S3. Mole weight: 499.5. | |
| SF 2315 A | SF 2315 A is a quinone antibiotic produced by Excellospora viridilutea SF2315. It exhibits inhibitory effect against Avian myelobastosis virus reverse transcriptase with IC50 of 100 μg/mL. It has weak activity against gram-positive bacteria. Synonyms: Antibiotic SF 2315A; SF 2315A; SF2315A; cis-(+)-4a,5,6,12b-Tetrahydro-4a,8-dihydroxy-3-methylbenz(a)anthracene-1,7,12(4H)-trione. CAS No. 114687-52-4. Molecular formula: C19H16O5. Mole weight: 324.3. | |
| SF 2315 B | SF 2315 B is a quinone antibiotic produced by Excellospora viridilutea SF2315. It exhibits inhibitory effect against Avian myelobastosis virus reverse transcriptase with IC50 of 40 μg/mL. It has weak activity against gram-positive bacteria. Synonyms: Antibiotic SF 2315B; SF 2315B; SF2315B. CAS No. 114687-53-5. Molecular formula: C19H20O5. Mole weight: 344.4. | |
| SF-2330 | SF-2330 is a quinone antibiotic produced by Streptomyces sp. SF-2330. It exhibits activity against gram-positive bacteria. Synonyms: Antibiotic SF-2330; SF 2330; 4H-Anthra(1,2-b)pyran-4,7,12-trione, 2-(2,2'-bioxiran)-2-yl-11-hydroxy-5-methyl-. CAS No. 103947-06-4. Molecular formula: C22H14O7. Mole weight: 390.3. | |
| SF-2415A1 | SF-2415A1 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415A1; SF 2415A1. CAS No. 110200-32-3. Molecular formula: C26H31ClN2O5. Mole weight: 487. | |
| SF-2415A2 | SF-2415A2 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415A2; SF 2415A2. CAS No. 110200-31-2. Molecular formula: C26H30N2O5. Mole weight: 450.5. | |
| SF-2415A3 | SF-2415A3 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415A3; SF 2415A3. CAS No. 110200-33-4. Molecular formula: C26H30Cl2N2O5. Mole weight: 521.4. | |
| SF-2415B1 | SF-2415B1 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415B1; SF 2415B1. CAS No. 110200-34-5. Molecular formula: C26H33ClO5. Mole weight: 461. | |
| SF-2415B2 | SF-2415B2 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415B2; SF 2415B2. Molecular formula: C26H32O5. Mole weight: 424.53. | |
| SF-2415B3 | SF-2415B3 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415B3; SF 2415B3. Molecular formula: C26H32Cl2O5. Mole weight: 495.43. | |
| SF 2446A1 | SF 2446A1 is a quinone antibiotic produced by Steptomyces sp. SF2446. SF 2446A1, SF 2446A2, SF 2446B1 have potent activity against mycoplasma with MIC of 0.01-0.03μg/mL, and activity against gram-positive bacteria. Synonyms: Antibiotic SF 2446A1; SF2446A1. Molecular formula: C34H35NO15. Mole weight: 697.6. | |
| SF 2446A2 | SF 2446A2 is a quinone antibiotic produced by Steptomyces sp. SF2446. SF 2446A1, SF 2446A2, SF 2446B1 have potent activity against mycoplasma with MIC of 0.01-0.03μg/mL, and activity against gram-positive bacteria. Synonyms: Antibiotic SF 2446A2; SF2446A2. Molecular formula: C34H35NO15. Mole weight: 697.6. | |
| SF 2446A3 | SF 2446A3. Synonyms: SF2446A3. CAS No. 115834-24-7. Molecular formula: C26H21NO11. Mole weight: 523.4. | |
| SF 2446B1 | SF 2446B1 is a quinone antibiotic produced by Steptomyces sp. SF2446. SF 2446A1, SF 2446A2, SF 2446B1 have potent activity against mycoplasma with MIC of 0.01-0.03μg/mL, and activity against gram-positive bacteria. Synonyms: Antibiotic SF 2446B1; SF2446B1. Molecular formula: C34H35NO14. Mole weight: 681.6. | |
| SF 2446B2 | SF 2446B2. Synonyms: SF2446B2. Molecular formula: C34H35NO14. Mole weight: 681.6. | |
| SF2457 | SF2457 is an antibiotic related to amicetin, which is isolated from the fermentation broth of Nocardia brasiliensis SF2457. It exhibits inhibitory activity against Gram-positive and Gram-negative bacteria. Synonyms: SF-2457; SF 2457. CAS No. 115748-04-4. Molecular formula: C27H38N6O9. Mole weight: 590.6. | |
| SF 2487 | SF 2487 is a polyether antibiotic produced by Actinomadura sp. SF2487. It has moderate activity against gram-positive bacteria including staphylococcus and enterococcus with MIC of 0.10-0.39 μg/mL. It also effective against Influenza A virus. Synonyms: SF-2487; SF2487; SF 2487 sodium salt; Antibiotic SF 2487 sodium salt; LS-70212. Molecular formula: C42H63NaO12. Mole weight: 782.9. | |
| SF2738C | SF2738C is an antibiotic produced by the strain of Streptomyces sp. It has moderate activity against gram-positive, gram-negative bacteria and fungi. Synonyms: SF-2738C; SF 2738C. Molecular formula: C13H14N2O2S. Mole weight: 262.33. | |
| SF-773α | SF-773α is an antibiotic produced by Streptomyces sp. It is active against gram-positive bacteria. Synonyms: SF 773α. Molecular formula: C17H34N4O10. Mole weight: 454.5. | |
| Shincomycin B | It is a macrolide antibiotic produced by the strain of Str. flavochromogenes R-903. It has anti-gram-positive bacteria and mycoplasma activity, and has no cross-resistance with erythromycin and mycomycin. Grade: 99%. CAS No. 11053-05-7. Molecular formula: C52H90NO20. Mole weight: 1049.26. | |
| Shinorine | Shinorine, a mycosporine-like amino acid (MAA) and an analog of porphyra-344, is a small molecule sunscreen produced by some bacteria with antioxidant, anti-UV, and sun protection properties. Shinorine ameliorates chromium-induced toxicity in zebrafish hepatocytes through facultatively activating the Nrf2-Keap1-ARE pathway. Both porphyrin-334 and Shinorine antioxidants and direct antagonists of Keap1-Nrf2 binding. Shinorine may be an effective drug to prevent or delay the progression of a variety of degenerative aging diseases. Synonyms: L-Serine, N-[3-[(carboxymethyl)amino]-5-hydroxy-5-(hydroxymethyl)-2-methoxy-2-cyclohexen-1-ylidene]-; demethyl-analog of Porphyra 334; N-[3-[(Carboxymethyl)amino]-5-hydroxy-5-(hydroxymethyl)-2-methoxy-2-cyclohexen-1-ylidene]-L-serine. Grade: ≥95%. CAS No. 73112-73-9. Molecular formula: C13H20N2O8. Mole weight: 332.31. | |
| Shurimycin A | It is produced by the strain of Str. hygroscopicus A1491. It has anti-gram-positive bacteria and fungi effects. Synonyms: Scopafungin, 2,3-didehydro-35-de[11-[[imino(methylamino)methyl]amino]-1,3-dimethyl-7-undecenyl]-2-demethyl-3-deoxy-35-[9-[[imino(methylamino)methyl]amino]-1-methyl-5-nonenyl]-30-methyl-; MBA 028-24A; Antibiotic MBA 028-24A. CAS No. 143906-47-2. Molecular formula: C56H95N3O17. Mole weight: 1082.36. | |
| Shurimycin B | It is produced by the strain of Str. hygroscopicus A1491. It has anti-gram-positive bacteria and fungi effects. Synonyms: Scopafungin, 35-[9-[[bis(methylamino)methylene]amino]-1-methyl-5-nonenyl]-2,3-didehydro-35-de[11-[[imino(methylamino)methyl]amino]-1,3-dimethyl-7-undecenyl]-2-demethyl-3-deoxy-30-methyl-; Antibiotic MBA 028-24B. CAS No. 143906-45-0. Molecular formula: C57H97N3O17. Mole weight: 1096.39. | |
| Siastatin B | A-72363 B is a Heparanase inhibitor produced by Streptomyces nobilis SANK 60192. Synonyms: A-72363 B; 3-Piperidinecarboxylic acid, 6-(acetylamino)-4,5-dihydroxy-, (3S-(3-alpha,4-alpha,5-alpha,6-beta))-; Siastatin B microbial; (2s,3r,4s,5s)-2-(Acetylamino)-5-Carboxy-3,4-Dihydroxypiperidinium. Grade: 95%. CAS No. 54795-58-3. Molecular formula: C8H14N2O5. Mole weight: 218.21. | |
| Sibanomicin | It is produced by the strain of Micronconospora sp. SF2364. It has weak effect against gram-positive bacteria. Mice inoculated with leukemic P388 cells were given 2.1 and 1.0 mg/kg, which extended the survival time by 96% and 69% compared with the control group. Synonyms: 7-[[3-C-Methyl-4-(methylamino)-4,6-dideoxy-α-L-mannopyranosyl]oxy]-1,2,3,11a-tetrahydro-2-[(E)-propylidene]-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one; 5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 7-[[4,6-dideoxy-3-C-methyl-4-(methylamino)-a-L-mannopyranosyl]oxy]-1,2,3,11a-tetrahydro-2-propylidene-, (2E)-; Antibiotic SF 2364. CAS No. 117782-84-0. Molecular formula: C23H31N3O5. Mole weight: 429.51. | |
| Siderochelin A | It is produced by the strain of Nocardia sp. SC 113, Act. sp. 69-209B-89. It has the effect against aerobic and anaerobic bacteria, and has anti-Gram-positive bacteria, Gram-negative bacteria and fungal effects but no anti-Candida albicans effect. The antibacterial activity of Siderochelin A is weaker than iron chelating agent Apoferrosamine. Fe2+, Fe3+, CO2+ and Zn2+ have antagonistic effects on Siderochelin A. Synonyms: 2H-Pyrrole-2-carboxamide, 3,4-dihydro-4-hydroxy-5-(3-hydroxy-2-pyridinyl)-4-methyl-, (2S,4R)-; 2H-Pyrrole-2-carboxamide, 3,4-dihydro-4-hydroxy-5-(3-hydroxy-2-pyridinyl)-4-methyl-, (2S-trans)-; Antibiotic EM 4940A. CAS No. 77550-87-9. Molecular formula: C11H13N3O3. Mole weight: 235.24. | |
| Siderochelin B | It is produced by the strain of Nocardia sp. SC 113, Act. sp. 69-209B-89. It has only weak effect against individual strains, such as E. coli. Synonyms: (2R)-3,4-Dihydro-4β-hydroxy-5-(3-hydroxypyridin-2-yl)-4-methyl-2H-pyrrole-2β-carboxamide. CAS No. 77518-26-4. Molecular formula: C11H13N3O3. Mole weight: 235.24. | |
| Siderochelin C | It is produced by the strain of Act. sp. 69-209B-89. It has only weak effect against individual strains, such as E. coli. Synonyms: (2S)-3,4-Dihydro-4β-hydroxy-5-(3-hydroxypyridin-2-yl)-4-ethyl-2H-pyrrole-2α-carboxamide; (2S,4R,5Z)-4-ethyl-4-hydroxy-5-(3-oxopyridin-2-ylidene)pyrrolidine-2-carboxamide; 2H-Pyrrole-2-carboxamide, 4-ethyl-3,4-dihydro-4-hydroxy-5-(3-hydroxy-2-pyridinyl)-, (2S-trans)-. CAS No. 93973-61-6. Molecular formula: C12H15N3O3. Mole weight: 249.27. | |
| Simocyclinone D4 | It is produced by the strain of Streptomyces antibioticus Tu 6040. It has moderate anti-gram-positive bacteria activity and has inhibitory effect on a variety of tumor cells. It inhibits HMO2, MCF7 and HEP G2 cells with GI50 (μmol/L) of 0.30, 5.6 and 8.5, respectively. Molecular formula: C46H43NO18. Mole weight: 897.83. | |
| Simocyclinone D8 | It is produced by the strain of Streptomyces antibioticus Tu 6040. It has moderate anti-gram-positive bacteria activity and has inhibitory effect on a variety of tumor cells. It inhibits HMO2, MCF7 and HEP G2 cells with GI50 (μmol/L) of 0.50, 0.95 and >50, respectively. Synonyms: 9-[4-O-Acetyl-3-O-[10-[(8-chloro-4,7-dihydroxy-2-oxo-2H-1-benzopyran-3-yl)amino]-1,10-dioxo-2,4,6,8-decatetraenyl]-2,6-dideoxy-beta-D-arabino-hexopyranosyl]-4a,5,6,12b-tetrahydro-4a,6,7,8,12b-pentahydroxy-3-methyl-6a,12a-epoxybenz[a]anthracene-1,12(4H,7H)-dione; (1R)-4-O-acetyl-1,5-anhydro-3-O-{(2E,4E,6E,8E)-10-[(8-chloro-4,7-dihydroxy-2-oxo-2H-chromen-3-yl)amino]-10-oxodeca-2,4,6,8-tetraenoyl}-2,6-dideoxy-1-[(4aR,6S,6aS,7S,12aS,12bR)-4a,6,7,8,12b-pentahydroxy-3-methyl-1,12-dioxo-1,4,4a,5,6,7,12,12b-octahydro-6a,12a-epoxytetraphen-9-yl]-D-arabino-hexitol. Grade: ≥95%. CAS No. 301845-97-6. Molecular formula: C46H42ClNO18. Mole weight: 932.27. | |
| Simonyellin | Simonyellin is a naphthopyran from the lichen Simonyella variegata Steiner. CAS No. 173322-91-3. Molecular formula: C14H10O6. Mole weight: 274.23. | |
| Siomycin | Siomycin is a peptide antibiotic that interacts with the 50S ribosomal subunit and inhibits binding of factor G and aminoacyl-tRNA. It exhibits antitumor activity against certain cancer cell lines. CAS No. 11017-43-9. Molecular formula: C64H88N16O22S4. Mole weight: 1561.73. | |
| Sirodesmin A | Sirodesmin A is a diketopiperazine antibiotic isolated from the culture broth of Microsphaeropsis sp. FL-16144. TAN-1496 inhibited the relaxation of supercoiled pBR322 DNA by calf thymus topoisomerase I but did not affect the decatenation of kinetoplast DNA by calf thymus topoisomerase II at concentration up to 500 microM. Synonyms: TAN-1496B; TAN 1496B. CAS No. 52988-50-8. Molecular formula: C20H26N2O8S2. Mole weight: 486.6. | |
| Sirodesmin B | It is produced by the strain of Sirodesmum diversum. It has antiviral effect. Synonyms: Spiro[furan-2(3H),9'(10'H)-[5,11a](iminomethano)[11aH]cyclopenta[4,5]pyrrolo[2,1-e][1,2,3,4,6]tetrathiazocine]-3,6',12'(5'H)-trione, 10'-(acetyloxy)-4,5,7'a,8',10'a,11'-hexahydro-10'ahydroxy-5'-(hydroxymethyl)-4,4,5,13'-tetramethyl-, (2R,5'R,7'aR,10'S,10'aS,11aR)-. CAS No. 52988-51-9. Molecular formula: C20H26N2O8S4. Mole weight: 550.69. | |
| Sirodesmin C | It is produced by the strain of Sirodesmum diversum. It has antiviral effect. Synonyms: Spiro[furan-2(3H),8'(9'H)-[4,10a](iminomethano)[10aH]cyclopenta[4,5]pyrrolo[2,1-d][1,2,3,5]trithiazepine]-3,5',11'(4'H)-trione, 9'-(acetyloxy)hexahydro-9'a-hydroxy-4'-(hydroxymethyl)-4,4,5,12'-tetramethyl-, (2R,4'R,5R,6'aR,9'S,9'aS,10aR)-. CAS No. 52988-52-0. Molecular formula: C20H26N2O8S3. Mole weight: 518.62. | |
| Sirodesmin G | It is produced by the strain of Sirodesmum diversum. It has antiviral effect. CAS No. 64599-26-4. Molecular formula: C20H26N2O8S2. Mole weight: 486.56. | |
| Sisomicin B | It is an aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis. It has broad-spectrum antimicrobial activity. Synonyms: Sisomicin B; 6-O-[3-Deoxy-3-(methylamino)-α-D-xylopyranosyl]-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hexa-4-enopyranosyl)-2-deoxy-D-streptamine; Antibiotic 66-40B; 6640B; D-Streptamine, O-3-deoxy-3-(methylamino)-alpha-D-xylopyranosyl-(1-6)-o-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-4))-2-deoxy-. CAS No. 53797-16-3. Molecular formula: C18H35N5O7. Mole weight: 433.50. | |
| Sisomicin D | It is an aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis. It has broad-spectrum antimicrobial activity. Synonyms: 6-O-[3-Deoxy-3-(methylamino)-β-L-arabinopyranosyl]-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hexa-4-enopyranosyl)-2-deoxy-D-streptamine; Antibiotic 66-40D; 66-40D. CAS No. 53759-50-5. Molecular formula: C18H35N5O7. Mole weight: 433.50. | |
| SM 196A | SM 196A is a quinone antibiotic produced by Streptomyces sp. DMS 4769. It exhibits activity against gram-positive bacteria. Synonyms: SM-196A. CAS No. 135635-82-4. Molecular formula: C20H20O5. Mole weight: 340.4. | |
| SM 196B | SM 196B is a quinone antibiotic produced by Streptomyces sp. DMS 4769. Its activity against gram-positive bacteria is more potent than that of SM 196A. It also has anti-Herpes simplex virus activity. Synonyms: SM-196B. CAS No. 135635-83-5. Molecular formula: C20H18O5. Mole weight: 338.4. | |
| SMTP-1 | SMTP-1 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C25H35NO5. Mole weight: 429.5. | |
| SMTP-2 | SMTP-2 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. The activity of SMTP-2 is weaker than SMTP-1. Molecular formula: C25H37NO7. Mole weight: 463.6. | |
| SMTP-3 | SMTP-3 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C26H35NO7. Mole weight: 473.6. | |
| SMTP-4 | SMTP-4 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C32H39NO6. Mole weight: 533.7. | |
| SMTP-5 | SMTP-5 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C29H41NO6. Mole weight: 499.6. | |
| SMTP-6 | SMTP-6 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C34H40N2O6. Mole weight: 572.7. | |
| SN-706 | SN-706 is an anthracycline antibiotic produced by Actinomadura reseoviolacea var miuraensis. It is active against gram-positive and gram-negative bacteria, as well as inhibits KB and HeLa cells with IC50 of 0.54 ng/mL. Synonyms: Antibiotic SN 706; SN 706. CAS No. 114511-93-2. Molecular formula: C36H45NO14. Mole weight: 715.7. | |
| SNA-4606-1 | SNA-4606-1 is an elaiophylin antibiotic isolated from Streptomyces sp. SNA-4606. It acts as a testosterone 5 alpha-reductase inhibitor with IC50 of 6.6 μmol/L. Molecular formula: C52H84O18. Mole weight: 997.2. | |
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