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Terphenyllin
Terphenyllin is a naturally abundant p-terphenyl metabolite isolated from the coral derived fungus Aspergillus candidus, has significant α-glucosidase inhibitory activity. Grade: >99% by HPLC. CAS No. 52452-60-5. Molecular formula: C20H18O5. Mole weight: 338.35.
Terreulactone A
Tetracycline A is an acetylcholinesterase (AchE, EC3. 1.1.7) inhibitor produced by Aspergillus terreus. It has a strong inhibition of AchE activity with IC50 of 0.23 μmol/L. Synonyms: 13-hydroxy-16-methoxy-8-(4-methoxyphenyl)-4,14,19,19-tetramethyl-5,9,18-trioxapentacyclo[14.2.1.01,14.04,13.06,11]nonadeca-6(11),7-diene-10,15,17-trione. Molecular formula: C28H30O9. Mole weight: 510.53.
Terreulactone B
Tetracycline B is an acetylcholinesterase (AchE, EC3. 1.1.7) inhibitor produced by Aspergillus terreus. It has a strong inhibition of AchE activity with IC50 of 0.09 μmol/L. Molecular formula: C27H30O7. Mole weight: 466.52.
Terreulactone C
Tetracycline C is an acetylcholinesterase (AchE, EC3. 1.1.7) inhibitor produced by Aspergillus terreus. It has a strong inhibition of AchE activity with IC50 of 0.06 μmol/L. Molecular formula: C27H32O7. Mole weight: 468.54.
Terreulactone D
Tetracycline D is an acetylcholinesterase (AchE, EC3. 1.1.7) inhibitor produced by Aspergillus terreus. It has a strong inhibition of AchE activity with IC50 of 0.42 μmol/L. Molecular formula: C30H36O10. Mole weight: 556.60.
Territrem B
Territrem B is a mycotoxin originally isolated from Aspergillus terreus that irreversibly inhibits acetylcholinesterase (AChE). Synonyms: (4aR,6aR,12aS,12bS)-4a,6,6a,12,12a,12b-Hexahydro-4a,12a-dihydroxy-4,4,6a,12b-tetramethyl-9-(3,4,5-trimethoxyphenyl)-4H,11H-naphtho[2,1-b]pyrano[3,4-e]pyran-1,11(5H)-dione; [4aR-(4aα,6aβ,12aα,12bβ)]-4a,6,6a,12,12a,12b-Hexahydro-4a,12a-dihydroxy-4,4,6a,12b-tetramethyl-9-(3,4,5-trimethoxyphenyl)-4H,11H-naphtho[2,1-b]pyrano[3,4-e]pyran-1,11(5H)-dione. Grade: ≥95%. CAS No. 70407-20-4. Molecular formula: C29H34O9. Mole weight: 526.57.
Testacein
Testosterone is isolated from the lichen Notoparmelia testacea. Molecular formula: C26H34O8. Mole weight: 474.55.
Tetradecanoyl-L-homoserine lactone
It is an active quorum sensing modulator first recognised in rhodobacter capsulatus. It has been detected in hundreds of bacterial species. Synonyms: C14-HSL; tDHL; N-Tetradecanoyl-L-homoserine lactone; (S)-N-(tetrahydro-2-oxo-3-furanyl)tetradecanamide; N-[(3S)-Tetrahydro-2-oxo-3-furanyl]tetradecanamide; (S)-N-tetradecanoyl-HSL; Tetradecanoylhomoserine lactone; N-Myristoyl-L-homoserine lactone. Grade: >99% by HPLC. CAS No. 202284-87-5. Molecular formula: C18H33NO3. Mole weight: 311.46.
Tetrafibricin
Tetrafibricin is a fibrinogen antagonist produced by Str. neyagawaensis NR0577. Tetrafibricin has a strong inhibitory effect on the binding of fibrinogen to the GP IIb/IIIa receptor with an IC50 of 46 nmol/L, and an IC50 of 46 mol/L for the inhibition of HeLa cell toxicity. Synonyms: 11,15,17,19,23,25,27,29,33,37-Decahydroxy-12-methyl-13-oxo-40-amino-2,4,6,8,20,30,34-tetracontaheptaenoic acid; 2,4,6,8,20,30,34-Tetracontaheptaenoic acid, 40-amino-11,15,17,19,23,25,27,29,33,37-decahydroxy-12-methyl-13-oxo-. CAS No. 151705-56-5. Molecular formula: C41H67NO13. Mole weight: 781.97.
Tetrahydroechinocandin B
Tetrahydroechinocandin B, a cyclic hexapeptide containing a fatty acyl side chain, inhibits 1,3-beta-D-glucan synthesis. It is an intermediate of anidulafungin. Synonyms: Echinocandin B, 1-[(4R,5R)-4,5-dihydroxy-N2-(1-oxooctadecyl)-L-ornithine]-; Echinocandin B, tetrahydro-; L 687,901; Octadecanimidic acid, N-[(2R,6S,7E,9S,11R,12R,14aS,15S,16S,20S,23R,24E,25aS)-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,3,5,6,9,10,11,12,14a,15,16,17,19,20,23,25a-hexadecahydro-2,8,11,12,14,15,22,25-octahydroxy-6,20-bis[(1R)-1-hydroxyethyl]-16-methyl-5,19-dioxo-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacycloheneicosin-9-yl]-; L-687901. Grade: 95% by HPLC. CAS No. 54651-06-8. Molecular formula: C52H85N7O16. Mole weight: 1064.27.
Tetrahymanol
Tetrahymanol is a natural compound isolated from Rhodopseudomonas palustris. Synonyms: Gammaceran-3β-ol; Wallichiniol; gammaceran-3beta-ol; 5α-Gammaceran-3β-ol; Gammaceran-3-ol, (3β)-. Grade: 98.0%. CAS No. 2130-17-8. Molecular formula: C30H52O. Mole weight: 428.73.
Tetrahymanol acetate
Tetrahymanol acetate is a natural compound isolated from Bradyrhizobium japonicum. Synonyms: Tetrahymanolacetate; Acetic acid 5alpha-gammaceran-3beta-yl ester; tetrahymanyl acetate; Gammaceran-3-ol, 3-acetate, (3β)-; Acetic acid (3S,6aR,14bR)-4,4,6a,6b,9,9,12a,14b-octamethyl-docosahydro-picen-3-yl ester. Grade: 98.0%. CAS No. 2130-22-5. Molecular formula: C32H54O2. Mole weight: 470.77.
Tetrahymanone
Tetrahymanone is isolated from Bradyrhizobium japonicum. Synonyms: Gammaceran-3-one; (6aR,14bR)-4,4,6a,6b,9,9,12a,14b-Octamethyl-icosahydro-picen-3-one. Grade: ≥96%. CAS No. 17822-06-9. Molecular formula: C30H50O. Mole weight: 426.72.
Tetranactin
It is a member of the macrotetrolide complex produced by a range of streptomyces sp. It is a monovalent cation ionophore with high selectivity for ammonium and potassium. Unlike the other macrotetrolides, tetranactin exhibits potent insecticidal activity. It is a glycoprotein transportation inhibitor, an immunosuppressant, an antiproliferative and an antiallergic agent. Synonyms: 5,14,23,32-Tetrademethyl-5,14,23,32-tetraethylnonactin; S-3466-C; 4,13,22,31,37,38,39,40-Octaoxapentacyclo[32.2.1.17,10.116,19.125,28]tetracontane-3,12,21,30-tetrone, 5,14,23,32-tetraethyl-2,11,20,29-tetramethyl-, (1R,2R,5R,7R,10S,11S,14S,16S,19R,20R,23R,25R,28S,29S,32S,34S)-. Grade: >95% by HPLC. CAS No. 33956-61-5. Molecular formula: C44H72O12. Mole weight: 793.04.
Tetrangomycin
Tetrangomycin is a quinone antibiotic produced by Str. rimosus var. sp. NRRL 3016. It has activity against gram-positive bacteria, but has no protective effect on mice infected with the Smith strain of golden staphylococcus aureus. Synonyms: (+)-3,4-dihydro-3,8-dihydroxy-3-methylbenz(a)anthracene-1,7,12(2H)-trione; (-)-tetrangomycin; Benzanthramycin. CAS No. 7351-8-8. Molecular formula: C19H14O5. Mole weight: 322.31.
Tetranolin
Tetranolin is a lactone antibiotic produced by Act. sp. SS-1018. It has anti-Gram-positive bacteria activity and weak anti-mycobacterial activity. Synonyms: Lissoclinolide; Kissoclinolide; lissoclinolide tetrenolin. Grade: >98%. CAS No. 132074-82-9. Molecular formula: C11H12O4. Mole weight: 208.21.
Tetrazomine
Tetrazomine is an antibiotic produced by Saccharothrix mulabilis subsp. chichijimaensis. It is active against gram-positive bacteria, gram-negative bacteria and mycobacteria. It has cytotoxic activity and inhibits lymphoid leukemia L1210 and leukemia P388 with IC50 of 0.047 and 0.0140 μg/mL, respectively. CAS No. 132073-72-4. Molecular formula: C24H34N4O5. Mole weight: 458.55.
Tetrocarcin E1
Tetrocarcin E1 is a small component produced by Micromonospora chalcea KY 11091. It has gram-positive bacterial activity, moderate activity against Bacillus subtilis, and weaker activity against Staphylococcus. Synonyms: Tetronolide, 9-O-(4-O-Acetyl-2,6-Dideoxy-Alpha-L-Ribo-Hexopyranosyl)-17-O-(2,3,4,6-Tetradeoxy-4-((Methoxycarbonyl)Amino)-3-C-Methyl-3-Nitro-Beta-D-Xylo-Hexopyranosyl)-. CAS No. 82925-71-1. Molecular formula: C49H66N2O17. Mole weight: 955.05.
Tetrocarcin E2
Tetrocarcin E2 is a small component produced by Micromonospora chalcea KY 11091. It has gram-positive bacterial activity, moderate activity against Bacillus subtilis, and weaker activity against Staphylococcus. Synonyms: Tetronolide, 9-O-(3-O-acetyl-2,6-dideoxy-alpha-L-ribo-hexopyranosyl)-17-O-(2,3,4,6-tetradeoxy-4-((methoxycarbonyl)amino)-3-C-methyl-3-nitro-beta-D-xylo-hexopyranosyl)-. CAS No. 83259-66-9. Molecular formula: C49H66N2O17. Mole weight: 955.05.
Tetrocarcin F
Tetrocarcin F is a small component produced by Micromonospora chalcea KY 11091. It has gram-positive bacterial activity, moderate activity against Bacillus subtilis, and weaker activity against Staphylococcus. Synonyms: Tetrocarcin A, 4B-O-de(2,6-dideoxy-4-O-(2,3,6-trideoxy-alpha-L-erythro-hexopyranosyl)-alpha-L-ribo-hexopyranosyl)-. CAS No. 82612-05-3. Molecular formula: C55H76N2O19. Mole weight: 1069.19.
Tetrocarcin F1
Tetrocarcin F1 is a small component produced by Micromonospora chalcea KY 11091. It has gram-positive bacterial activity, moderate activity against Bacillus subtilis, and weaker activity against Staphylococcus. Synonyms: Antibiotic F1; Tetrocarcin F-1. CAS No. 81319-50-8. Molecular formula: C41H54N2O13. Mole weight: 782.87.
Tetrodecamycin
It is produced by the strain of Streptomyces nashvillensis MJ885-mF8. It has anti-gram-positive bacteria (MIC is 6.25-12.5 μg/mL) and PasteureRci pisciccida (MIC is 1.56-3.12 μg/mL) activity. Synonyms: (-)-tetrodecamycin; 5,11-Methanofuro(3,4-d)(3)benzoxonin-1,12(3H,5H)-dione,6,6a,7,8,9,10,10a,11-octahydro-6,6a-dihydroxy-11,13-dimethyl-3-methylene-, (5R-(5R*,6S*,6aR*,10aR*,11S*,13R*))-. CAS No. 156980-57-3. Molecular formula: C18H22O6. Mole weight: 334.36.
Tetronasin
Tetronasin is extracted from Streptomyces longisporoflavus. It has anti-gram-positive bacteria and anti-eimeria tenella activity. Synonyms: Tetronasina; Tetronasine; Tetronasinum; Antibiotic M 139603; ICI 139603; M 139603. Molecular formula: C35H54O8. Mole weight: 602.80.
Tetronomycin Sodium
Tetronomycin Sodium is a polycyclic ionophore polyether antibiotic produced by Str. sp. nov. S53161/A. It has anti-Gram-positive bacteria, Neisseria and Mycoplasma activity. Molecular formula: C34H49NaO8. Mole weight: 608.74.
Tetronothiodin
Tetronothiodin is a trypsin secretin type B receptor antagonist produced by Str. sp. NR0489. Tetronothiodin can inhibit the binding of trypsin C-terminal 8 peptide to rat cortical trypsin B receptor, with IC50 of 3.6 μmol/L. CAS No. 139643-79-1. Molecular formula: C31H38O8S. Mole weight: 570.69.
Thailanstatin B
Thailanstatin B is a pre-mRNA splicing inhibitor. Thailanstatin B is used as a cytotoxin for ADCs. Synonyms: EX-A5053. CAS No. 1426953-23-2. Molecular formula: C28H42ClNO9. Mole weight: 572.1.
Thapsigargicin
It is a hexaoxygenated tetra-acylated sesquiterpene lactone tetraester isolated from roots of Thapsia garganica. It induces mast cell degranulation and histamine release. Synonyms: Hexanoic acid, (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl ester. Grade: ≥90%. CAS No. 67526-94-7. Molecular formula: C32H46O12. Mole weight: 622.70.
Thapsigargin
Potent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostatin. Induces apoptosis by disrupting intracellular free Ca2+ levels; incorporated into chemotherapeutic prodrug formulations. In cells, sarco/endoplasmic calcium ATPases (SERCAs) transport free calcium into the sarcoplasmic and endoplasmic reticula, lowering intracellular calcium levels to stop signaling through this cation. Thapsigargin is a non-competitive, cell permeable inhibitor of calcium transport by SERCAs (IC50 values are cell type-dependent and range from ~2-80 nM). Inhibition of SERCAs leads to an increase in intracellular calcium, which has been linked to cell activation, release of histamine from mast cells, and increased proliferation of certain types of cancer cells. In vivo, thapsigargin and related sesquiterpene lactones have anti-inflammatory and anti-cancer effects. Uses: Enzyme inhibitors. Synonyms: Octanoic acid. Grade: >99%. CAS No. 67526-95-8. Molecular formula: C34H50O12. Mole weight: 650.75.
Thelephoric acid
Thelephoric acid is a terphenylquinone pigment found in several fungi, such as Omphalotus subilludens and Polyozellus multiplex. It is derived from atromentin, and its precusor can be from cyclovariegatin. Thelephoric acid has been shown to inhibit prolyl endopeptidase, an enzyme that plays a role in processing proteins (specifically, amyloid precursor protein) in Alzheimer's disease. Synonyms: 2,3,8,9-Tetrahydroxybenzo[1,2-b:4,5-b']bisbenzofuran-6,12-dione; Thelephorsaure; PM-B; 2,3'-Carbonyl-3,2'-carbonylbis(5,6-dihydroxybenzofuran); Thelephate. CAS No. 479-64-1. Molecular formula: C18H8O8. Mole weight: 352.25.
Thermorubin
Thermorubin A is an antibiotic produced by Thermoactinomyces antibioticus TA/124. It has broad-spectrum antibacterial effect, but weaker effect on mycobacteria. Serum has the effect of reducing antibacterial activity. It has a protective effect on mice infected with Staphylococcus aureus by intraperitoneal administration. Synonyms: Thermorubin A. CAS No. 37577-75-6. Molecular formula: C32H24O12. Mole weight: 600.52.
Thiamine hydrochloride
Thiamine or vitamin B1 is a water-soluble vitamin of the B complex, its phosphate derivatives are involved in many cellular processes. Uses: Ingredient of health care products. Synonyms: 3-((4-amino-2-methylpyrimidin-5-yl)methyl)-5-(2-hydroxyethyl)-4-methylthiazol-3-ium chloride hydrochloride. Grade: >95% by HPLC. CAS No. 67-03-8. Molecular formula: C12H18Cl2N4OS. Mole weight: 337.27.
Thiazinotrienomycin A
Thiazinotrienomycin A is an ansa antibiotic produced by Str. sp. MJ672-m3. It has the effect of inhibiting cancer cells, and the IC50 for inhibiting HeLa cells is 5.0 ng/mL. CAS No. 165337-93-9. Molecular formula: C38H49N3O8S. Mole weight: 707.87.
Thiazinotrienomycin E
Thiazinotrienomycin E is an ansa antibiotic produced by Str. sp. MJ672-m3. It has the effect of inhibiting cancer cells, and the IC50 for inhibiting HeLa cells is 13 ng/mL. CAS No. 165337-97-3. Molecular formula: C38H51N3O8S. Mole weight: 709.89.
Thiazinotrienomycin F
Thiazinotrienomycin F is an ansa antibiotic produced by Str. sp. MJ672-m3. It can inhibit the growth of tumor cells such as NCI-H522, NCI-H469, OVCAR-5, St-4 and BSY-1. Molecular formula: C37H47N3O7S. Mole weight: 677.85.
Thiazinotrienomycin G
Thiazinotrienomycin G is an ansa antibiotic produced by Str. sp. MJ672-m3. It can inhibit the growth of tumor cells such as NCI-H522, NCI-H469, OVCAR-5, St-4 and BSY-1. Molecular formula: C37H49N3O7S. Mole weight: 679.86.
Thidiazuron
A cytokinin-lilke plant hormone routinely used to promote plant tissue regeneration. Synonyms: Defolit; Dropp; Urea, N-Phenyl-N'-1,2,3-Thiadiazol-5-Yl-; TDZ. Grade: ≥95%. CAS No. 51707-55-2. Molecular formula: C9H8N4OS. Mole weight: 220.25.
Thielavin A
Thielavin A is a glucose-6-phosphatase (G6Pase) inhibitor produced by Chaetomium carinthiacum. Grade: >95% by HPLC. CAS No. 71950-66-8. Molecular formula: C29H30O10. Mole weight: 538.54.
Thielavin B
Thiourea B is a fungal metabolite that contains O-substituted salicylic acid. It is a fungal metabolite closely related to thiobactin A. It is an effective inhibitor of phospholipase C, which can inhibit the formation of peptidoglycan and the biosynthesis of prostaglandin. Synonyms: Thielavin-B. Grade: >95% by HPLC. CAS No. 71950-67-9. Molecular formula: C31H34O10. Mole weight: 566.59.
Thielavin D
Thielavin D is a glucose-6-phosphatase (G6Pase) inhibitor produced by Chaetomium carinthiacum. Molecular formula: C30H32O10. Mole weight: 552.57.
Thielavin P
Thielavin P is a glucose-6-phosphatase (G6Pase) inhibitor produced by Chaetomium carinthiacum. Molecular formula: C30H32O10. Mole weight: 552.57.
Thioactin
Thioactin is produced by the strain of Str. sp. DP94. The minimum inducing concentration of X to the promoter TIP-1 was 40 ng/mL. Molecular formula: C43H40N14O11S4. Mole weight: 1057.12.
Thiocoraline
Thiocoraline is a peptide antibiotic produced by Micromonospora sp. L-13-ACM2-092. It has strong anti-Gram-positive bacteria and weak anti-Gram-negative bacteria activity. The effect of inhibiting RNA synthesis is stronger than that of inhibiting DNA synthesis. Cytotoxic activity. Synonyms: Thicoraline; Thi Coraline. Grade: >98%. CAS No. 173046-02-1. Molecular formula: C48H56N10O12S6. Mole weight: 1157.41.
Thioformin
Thioformin is produced by Pseudomonas sp. MCRL 10107. It has broad-spectrum antibacterial and antifungal activity. Synonyms: N-Methyl-N-thioformylhydroxylamine; Fluopsin. CAS No. 31335-60-1. Molecular formula: C2H5NOS. Mole weight: 91.13.
Thiomarinol A
Thiomarinol A is produced by a marine bacterium Alteromonas rava SANK T3390. It is resistant to Gram-positive and Gram-negative bacteria and also has an effect on MRSA. Synonyms: (5S)-1,5-anhydro-2-deoxy-2-[(2E,4R,5S)-5-hydroxy-4-methylhex-2-en-1-yl]-5-[(1R,2E)-1-hydroxy-2-methyl-4-oxo-4-({8-oxo-8-[(5-oxo-4,5-dihydro[1,2]dithiolo[4,3-b]pyrrol-6-yl)amino]octyl}oxy)but-2-en-1-yl]-L-arabinitol. Grade: 96%. CAS No. 146697-04-3. Molecular formula: C30H44N2O9S2. Mole weight: 640.81.
Thiomarinol B
Thiomarinol B is produced by a marine bacterium Alteromonas rava SANK T3390. It is resistant to Gram-positive and Gram-negative bacteria and also has an effect on MRSA. Synonyms: (5S)-1,5-anhydro-2-deoxy-5-[(1R,2E)-4-({8-[(2,2-dioxido-5-oxo-4,5-dihydro[1,2]dithiolo[4,3-b]pyrrol-6-yl)amino]-8-oxooctyl}oxy)-1-hydroxy-2-methyl-4-oxobut-2-en-1-yl]-2-[(2E,4R,5S)-5-hydroxy-4-methylhex-2-en-1-yl]-L-arabinitol. Molecular formula: C30H44N2O11S2. Mole weight: 672.81.
Thiomarinol D
Thiomarinol D is produced by a marine bacterium Alteromonas rava SANK T3390. It is resistant to Gram-positive and Gram-negative bacteria and also has an effect on MRSA. Synonyms: (5S)-1,5-anhydro-2-deoxy-2-[(2E,4R,5S)-5-hydroxy-4-methylhept-2-en-1-yl]-5-[(1R,2E)-1-hydroxy-2-methyl-4-oxo-4-({8-oxo-8-[(5-oxo-4,5-dihydro[1,2]dithiolo[4,3-b]pyrrol-6-yl)amino]octyl}oxy)but-2-en-1-yl]-L-arabinitol. Molecular formula: C31H46N2O9S2. Mole weight: 654.83.
Thiomarinol E
Thiomarinol E is produced by a marine bacterium Alteromonas rava SANK T3390. It is resistant to Gram-positive and Gram-negative bacteria and also has an effect on MRSA. Synonyms: (5S)-1,5-anhydro-2-deoxy-2-[(2E,4R,5S)-5-hydroxy-4-methylhex-2-en-1-yl]-5-[(1R,2E)-1-hydroxy-2-methyl-4-oxo-4-({10-oxo-10-[(5-oxo-4,5-dihydro[1,2]dithiolo[4,3-b]pyrrol-6-yl)amino]decyl}oxy)but-2-en-1-yl]-L-arabinitol. Molecular formula: C32H48N2O9S2. Mole weight: 668.86.
Thiomelin
Thiomelin is isolated from the lichens Rinodina thiomela (Nyl.) Miill. Arg. and Rinodina lepida (Nyl). Miill. Arg. CAS No. 113734-83-1. Molecular formula: C15H10Cl2O5. Mole weight: 341.14.
Thiophaninic acid
Thiophaninic acid is a xanthone compound derived from Australian lichen. Synonyms: Xanthen-9-one, 2,4-dichloro-1,3-dihydroxy-6-methoxy-8-methyl- (8CI); 2,4-Dichloro-1,3-dihydroxy-6-methoxy-8-methyl-9H-xanthen-9-one. CAS No. 22105-96-0. Molecular formula: C15H10Cl2O5. Mole weight: 341.14.
Thiotetromycin
It is originally isolated from Str. sp. OM-674. Thiotetromycin has the effect of resisting anaerobe fragile bacteroidetes, and also resisting other bacteria, but the activity is weak. Synonyms: Antibiotic OM 674; (R-(E))-3,5-Diethyl-4-hydroxy-5-(2-methyl-1,3-butadienyl)-2(5H)-thiophenone; (2R)-2,4-diethyl-5-hydroxy-2-[(1E)-2-methylbuta-1,3-dienyl]thiophen-3-one. CAS No. 85263-97-4. Molecular formula: C13H18O2S. Mole weight: 238.35.
Thioxamycin
Thioxamycin is produced by the strain of Str. sp. DP94. The minimum inducing concentration of X to the promoter TIP-1 was 80 ng/mL. Synonyms: Sulfomycin I, 58-(1-carboxyethenyl)-28-deethylidene-14-de(2-hydroxypropylidene)-21-demethoxy-17,31-didemethyl-28-methyl-14-((methylthio)methyl)-30-thia-. Grade: ≥98%. CAS No. 124883-37-0. Molecular formula: C52H48N16O15S4. Mole weight: 1265.29.
Thrazarine
Thrazarine is produced by the strain of Str. coerulescens MH802 fF5. It inhibits DNA synthesis and the growth of tumor cells. Synonyms: O-((3R)-2-Diazo-3-hydroxybutyryl)-L-serine; (Z,3R)-1-[(2S)-2-amino-2-carboxyethoxy]-2-diazonio-3-hydroxybut-1-en-1-olate. Grade: ≥98%. CAS No. 120128-14-5. Molecular formula: C7H11N3O5. Mole weight: 217.18.
Threonyl-asparagine
Threonyl-asparagine is a dipeptide composed of threonine and asparagine. Synonyms: Thr-Asn; L-Threonyl-L-asparagine. CAS No. 330601-56-4. Molecular formula: C8H15N3O5. Mole weight: 233.22.
Threonyl-histidine
Threonyl-histidine is a dipeptide composed of threonine and histidine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Histidine, L-threonyl-; L-threonyl-L-histidine; H-TH-OH; Thr-His; L-Thr-L-His; N-L-Threoninyl-L-histidine. Grade: ≥95%. CAS No. 55831-93-1. Molecular formula: C10H16N4O4. Mole weight: 256.26.
Threonyl-isoleucine
Threonyl-isoleucine is a dipeptide composed of threonine and isoleucine. Synonyms: Thr-Ile; TI dipeptide; threonylisoleucine; T-I Dipeptide. CAS No. 129050-49-3. Molecular formula: C10H20N2O4. Mole weight: 232.28.
Threonyl-lysine
Threonyl-lysine is a dipeptide composed of threonine and lysine. Synonyms: Thr-Lys. CAS No. 23161-31-1. Molecular formula: C10H21N3O4. Mole weight: 247.29.
Threonyl-threonine
Threonyl-threonine is a dipeptide composed of two threonine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Threonine, L-threonyl-; L-threonyl-L-threonine; H-TT-OH; Thr-Thr; L-Thr-L-Thr; H-L-Thr-L-Thr-OH. Grade: ≥95%. CAS No. 96337-78-9. Molecular formula: C8H16N2O5. Mole weight: 220.22.
Threonyl-tyrosine is a dipeptide composed of threonine and tyrosine. CAS No. 145295-02-9. Molecular formula: C13H18N2O5. Mole weight: 282.29.
Thuringione
Thuringione can inhibit the growth of mouse SV40-transformed ileocecal blastoma cells in vitro. Synonyms: Xanthen-9-one, 2,4,5-trichloro-1,6-dihydroxy-3-methoxy-8-methyl- (8CI). CAS No. 22105-34-6. Molecular formula: C15H9Cl3O5. Mole weight: 375.59.
Tiacumicin A
It is originally isolated from Dactylosporangium aurantiacum sub sp. hamdenensis subsp. nov. AB718C-41. Tiacumicin A has the effect of resisting gram-positive bacteria. CAS No. 109713-94-2. Molecular formula: C34H52O9. Mole weight: 604.77.
Tiacumicin C
It is originally isolated from Dactylosporangium aurantiacum sub sp. hamdenensis subsp. nov. AB718C-41. Tiacumicin C has the effect of resisting gram-positive bacteria. Synonyms: Clostomicin B2; Lipiarmycin B3; Benzoic acid, 3,5-dichloro-4,6-dihydroxy-2-ethyl-, 4'(3)-ester with 3-(((6-deoxy-2-O-methyl-beta-L-mannopyranosyl)oxy)methyl)-12-((6-deoxy-5-C-methyl-2-O-(2-methyl-1-oxopropyl)-beta-D-lyxo-hexopyranosyl)oxy)-11-ethyl-8-hydroxy-18-(1-hydroxyethyl)-9,13,15-trimethyloxacyclooctadeca-3,5,9,13,15-pentaen-2-one. CAS No. 106008-70-2. Molecular formula: C52H74Cl2O18. Mole weight: 1058.04.
Tiacumicin F
It is originally isolated from Dactylosporangium aurantiacum sub sp. hamdenensis sub sp. nov. AB718C-41. Tiacumicin C has the effect of resisting gram-positive bacteria. It also has the activity of inhibiting pathogenic Staphylococcus aureus and multi-dose drug-resistant bacteria. Synonyms: Clostomycin A; Benzoic acid, 3,5-dichloro-4,6-dihydroxy-2-ethyl-, 4'(3)-ester with 3-(((6-deoxy-2-O-methyl-beta-L-mannopyranosyl)oxy)methyl)-12-((6-deoxy-5-C-methyl-3-O-(2-methyl-1-oxopropyl)-beta-D-lyxo-hexopyranosyl)oxy)-11-ethyl-8-hydroxy-18-(1-hydroxyethyl)-9,13,15-trimethyloxacyclooctadeca-3,5,9,13,15-pentaen-2-one; Fidaxomicin Impurity 4. CAS No. 106008-69-9. Molecular formula: C52H74Cl2O18. Mole weight: 1058.04.
TL-119
TL-119 is an antibiotic isolated from Bacillus subtilis. It is effective against gram-positive bacteria and fungi. Synonyms: Antibiotic TL-119; TL 119. CAS No. 55599-68-3. Molecular formula: C42H57N7O9. Mole weight: 803.9.
TMC-135A
TMC-135A is a triene-ansamycin antibiotic produced by Streptomyces sp. TC 1190. It is cytotoxic to HCT-116, SK-BR-3, HeLa S3, WiDr, HT29 and HL-60 with IC50 values of 0.07, 0.88, 0.11, 0.20, 0.15 and 0.05 μmol/L, respectively. Synonyms: TMC-135 A. Molecular formula: C39H49N3O8S. Mole weight: 719.9.
TMC-135B
TMC-135B is a triene-ansamycin antibiotic produced by Streptomyces sp. TC 1190. It is cytotoxic to HCT-116, SK-BR-3, HeLa S3, WiDr, HT29 and HL-60. Synonyms: TMC-135 B. Molecular formula: C39H49N3O8S. Mole weight: 719.9.
TMC-154
TMC-154 is an antibiotic produced by Gliocladium sp. TC 1282. It has cytotoxicity to cancer cells like HCT-1l6, H-60, U937, WiDr. Synonyms: TMC 154. Molecular formula: C41H72O14. Mole weight: 789.
TMC-169
TMC-169 is an antibiotic of the aspochalasin group produced by Aspergillus flavipes TC 1446. It has cytotoxicity. Synonyms: TMC 169. Molecular formula: C24H35NO3. Mole weight: 385.5.
TMC-171A
TMC-171A is a polyketide antibiotic produced by Gliocladium sp. TC 1304. It has cytotoxicity to cancer cells like HCT-1l6, H-60, U937, WiDr. Synonyms: TMC-171 A. Molecular formula: C41H72O15. Mole weight: 805.
TMC-171B
TMC-171B is a polyketide antibiotic produced by Gliocladium sp. TC 1304. It has cytotoxicity to cancer cells like HCT-1l6, H-60, U937, WiDr. Synonyms: TMC-171 B. Molecular formula: C41H72O15. Mole weight: 805.