BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Valanimycin | Valanimycin is produced by the strain of Str. viridifaciens MG456-hF10 (FERMP8146). It has anti-Gram-positive bacteria and negative bacteria action and the effect on anti-Gram-negative bacteria is stronger. In vitro, the IC50 of it on murine leukemia cell line L-1210 was 0.79 μg/mL. Synonyms: 2-[(2-methylpropyl)-ONN-azoxy]acrylic acid. CAS No. 101961-60-8. Molecular formula: C7H12N2O3. Mole weight: 172.18. |  |
| Vanoxonin | Vanoxonin is produced by the strain of Saccharopolyspora hirsuta. It can inhibit thymidylate synthase (IC50 = 0.7μg/mL). And the MIC of the complex against L-1210 and Ehrlich ascites cancer cells was 25 μg/mL. Synonyms: Antibiotic MG 245CF2A; N(sup 5)-Acetyl-N(sup 2)-(N-(2,3-dihydroxybenzoyl)-L-threonyl)-N(sup 5)-hydroxy-L-ornithine; (S)-2-((2S,3R)-2-(2,3-dihydroxybenzamido)-3-hydroxybutanamido)-5-(N-hydroxyacetamido)pentanoic acid. CAS No. 86933-99-5. Molecular formula: C18H25N3O9. Mole weight: 427.40. | |
| Variamycin | Variamycin is a glycoside antibiotic originally isolated from Streptomyces olivovariabilis 6604-9. It has the effect of resisting gram-positive bacteria, fungi and tumors. Synonyms: Variamitsin; Varamycin; NSC 269146; Antibiotic 6604-9A; 3(C)-Demethyl-4(C)-O-methylmithramycin. CAS No. 12677-11-1. Molecular formula: C52H76O24. Mole weight: 1085.14. | |
| VD-846 | VD-846 is an antibiotic produced by Streptomyces sp. with activity against gram-positive and -negative bacteria. Synonyms: Antibiotic VD 846 B; VD 846 B. CAS No. 21787-66-6. Molecular formula: C6H4N2O2S2. Mole weight: 200.2. | |
| VERATRIDINE | Veratridine, a pentacyclic triterpene acid compound, has been found to be a steroid-derived alkaloid neurotoxin and could be used as a voltage-gated Na+ channel opener. Synonyms: Veratrin (Amorphous); (3β,4α,16β)-4,12,14,16,17,20-Hexahydroxy-4,9-epoxycevan-3-yl 3,4-dimethoxybenzoate. Grade: ≥90% by HPLC. CAS No. 71-62-5. Molecular formula: C36H51NO11. Mole weight: 673.79. | |
| Verdamycin | It is produced by the strain of Micromonospora grisea. Verdamycin has anti-bacterial effect. In in vivo test of mice, it has protective effect on the infection of Escherichia coli, Pseudomonas aeruginosa and Staphylococcus. Synonyms: Verdamicin; O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6-)-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-threo-hept-4-enopyranosyl-(1-4))-2-deoxy-D-streptamine. Grade: 98%. CAS No. 49863-48-1. Molecular formula: C20H39N5O7. Mole weight: 461.55. | |
| Verlamelin | It is a depsipeptide antibiotic produced by the strain of Fungi MF 4683. It has anti-fungal activity against plant pathogens. Synonyms: MSD-A-43F; Verlamelin; A-43F; Antibiotic MSD-A-43F; Antibiotic A-43F; Cyclo[D-Tyr-5-L-Val-oxytetradecanoyl-D-aThr-D-Ala-L-Pro-L-Glu(NH2)-]. CAS No. 74758-64-8. Molecular formula: C45H71N7O11. Mole weight: 886.09. | |
| Vermiculine | Vermiculine is produced by the strain of Pen. vermiculatum CCM-F-2. It has anti-protozoal and anti-tumor effects, and it also has a less potent effect against gram-positive bacteria. Synonyms: Vermiculin; NSC657321; (-)-Vermiculine; 1,11-diene-2,5,10,13-tetrone,8,16-bis(2-oxopropyl)-, (3E,8S,11E,16S)-. CAS No. 37244-00-1. Molecular formula: C20H24O8. Mole weight: 392.40. | |
| Vermistatin | It is a new metabolite from mine-dwelling Penicillium vermiculatum. It is an antibiotic with cytotoxic effects. Synonyms: (R,E)-4,6-dimethoxy-3-(4-oxo-6-(prop-1-en-1-yl)-4H-pyran-3-yl)isobenzofuran-1(3H)-one; Fijiensin; (-)-Fijiensin; NSC 656107; 1(3H)-Isobenzofuranone, 4,6-dimethoxy-3-(4-oxo-6-(1-propenyl)-4H-pyran-3-yl)-, (R)-; 5-(4,6-Dimethoxy-3R-phthalidy)-2-(1E)-propenyl-4H-pyran-4-one. CAS No. 72669-21-7. Molecular formula: C18H16O6. Mole weight: 328.32. | |
| Vernamycin B | Vernamycin B is originally isolated from Str. loidensis. Vernamycin B has an antimicrobial effect, but is less effective against gram-negative bacteria and mycobacteria. CAS No. 9040-14-6. Molecular formula: C62H85N7O16S. Mole weight: 1216.44. | |
| Verrucarin B | It is produced by the strain of Myrothecium verrucaria NRRL 3003. Verrucarin B has an effect on Ascites carcinoma, also has a weak inhibitory effect on fungi. Synonyms: (2'S,3'R)-2'-Deoxy-2',3'-oxyverrucarin A. CAS No. 2290-11-1. Molecular formula: C27H32O9. Mole weight: 500.54. | |
| Verrucarin K | Verrucarin K is produced by the strain of Myrothecium verrucaria NRRL 3003. The ED50 of Verrucarin K on giant cell tumor P-815 cells was about 0.001 μg/mL. Synonyms: BRN 1276841; Verrucarin A, 12,13-deepoxy-12,13-didehydro-. CAS No. 63739-93-5. Molecular formula: C27H34O8. Mole weight: 486.55. | |
| Verrucofortine | A diketopiperazine alkaloid derived from tryptophan and leucine. It is a fungal metabolite isolated from penicillium verrucosum. It exhibits no apparent toxicity in mice even at high doses in vivo. Synonyms: Fructigenine B; Verrucosine; Verrucozine; (-)-Verrucofortine; (3S-(3alpha,5aalpha,10balpha,11abeta))-6-Acetyl-10b-(1,1-dimethyl-2-propenyl)-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino(1',2':1,5)pyrrolo(2,3-b)indole-1,4-(3H,5aH)-dione; (3S,5aR,10bR,11aS)-6-acetyl-10b-(1,1-dimethyl-2-propen-1-yl)-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione. Grade: >99% by HPLC. CAS No. 113706-21-1. Molecular formula: C24H31N3O3. Mole weight: 409.52. | |
| Verruculogen | Verruculogen is a tremorgenic mycotoxin isolated from penicillium verruculosu. It can inhibit the K+ channel activated by ca2+, and is a cell cycle inhibitor that prevents M phase division. Synonyms: TR 1 toxin. Grade: >95% by HPLC. CAS No. 12771-72-1. Molecular formula: C27H33N3O7. Mole weight: 511.57. | |
| Versicolin | Versicolin is originally isolated from Asp. versicolor. It only has antibacterial effect on filamentous fungi, and has no inhibitory effect on yeast-like fungi and bacteria. Synonyms: 2,3,6-Trihydroxytoluene; Toluene-2,3,6-triol; BRN 2249549; 1-methyl-2,3,6-trihydroxybenzene. CAS No. 4389-44-0. Molecular formula: C7H8O3. Mole weight: 140.14. | |
| Versicolorin A | Versicolorin A is a quinone antibiotic produced by the strain of Asp. versicolor. It has the effect of anti-tuberculosis Mycobacterium H37RV and other mycobacteria. Synonyms: Z-(-)-4,6,8-Trihydroxy-3a,12a-dihydroanthra(2,3-b)furo(3,2-d)furan-5,10-dione; NSC 274542; (3aS,12aR)-4,6,8-trihydroxy-3a,12a-dihydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione. Grade: 98%. CAS No. 6807-96-1. Molecular formula: C18H10O7. Mole weight: 338.27. | |
| Versicolorin B | Versicolorin B is a quinone antibiotic produced by the strain of Asp. versicolor. It has the effect of anti-tuberculosis Mycobacterium H37RV and other mycobacteria. Synonyms: (3aS,12aR)-4,6,8-trihydroxy-2,3,3a,12a-tetrahydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione; Anthra(2,3-b)furo(3,2-d)furan-5,10-dione, 2,3,3a,12a-tetrahydro-4,6,8-trihydroxy-, cis-(+-)-. CAS No. 4331-22-0. Molecular formula: C18H12O7. Mole weight: 340.28. | |
| Verticillin B | Verticillin B is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Synonyms: (6S,6'S)-19-Deoxy-6,6'-dihydroxychetocin. CAS No. 52212-86-9. Molecular formula: C30H28N6O7S4. Mole weight: 712.84. | |
| Vertimycin | It is a cyclopentane derivative of antibiotic produced by the strain of Streptoverticillium sp. JA 4498. It has anti-gram-positive bacteria and fungal effects. It has weak effect on Ehrlich ascites cancer cells in vitro. Synonyms: Cyclopentanone, 2-(2-hydroxyethoxy)-5-(hydroxymethyl)-; 1-Ethylenodiolo-3-methylolo-cyclopentanone-2; 1-(Aethylendiol-1,2)-methylol-3-cyclopentanon-2. CAS No. 14477-60-2. Molecular formula: C8H14O4. Mole weight: 174.19. | |
| Vertisporin | It is an antibiotic produced by the strain of Verticimonosporium diffractum TM-2098 and TM-2492. It has the effect against a few fungal. It is cytotoxic to HeLa cells with ED50 of 0.001 μg/mL. Synonyms: Spiro[4H-3a,22-(epoxyethano)-10,12-methano-17H,18H-furo[2',3':10,11][1,6]dioxacyclohexadecino[3,4-d][1]benzopyran-11(12H),2'-oxirane]-8,20(5H,22aH)-dione,2,3,10,10a,13a,16-hexahydro-2,3-dihydroxy-10a,15-dimethyl-, (2R,2'S,3R,3aR,6Z,10R,10aS,12R,13aR,17aR,21E,21bR)-. CAS No. 57100-32-0. Molecular formula: C29H36O10. Mole weight: 544.59. | |
| Vibralactone B | Vibralactone B is an antibacterial compound produced from liquid fermentations of Stereum hirsutum that inhibits the growth of E. coli and Pseudomonas aeruginosa. Synonyms: (1beta)-2alpha-Prenyl-3beta-hydroxy-5beta-(hydroxymethyl)-6-oxabicyclo[3.1.0]hexane-2-carboxylic acid 2,3-lactone; 3,7-Dioxatricyclo[4.2.0.02,4]octan-8-one, 4-(hydroxymethyl)-1-(3-methyl-2-buten-1-yl)-, (1S,2R,4R,6S)-; (1S,2R*,3R*,5S)-2,3-epoxyvibralactone. Grade: ≥98%. CAS No. 1093230-95-5. Molecular formula: C12H16O4. Mole weight: 224.25. | |
| Vibralactone D | Vibralactone D is isolated from Boreostereum vibrans and exhibits weak inhibitory effect against isozymes of 11beta-hydroxysteroid dehydrogenases (HSD). Synonyms: (1S,5R,6S)-6-hydroxy-5-(3-methylbut-2-enyl)-3-oxabicyclo[3.2.1]octan-4-one; 3-Oxabicyclo[3.2.1]octan-2-one, 7-hydroxy-1-(3-methyl-2-buten-1-yl)-, (1R,5S,7S)-. Grade: ≥98%. CAS No. 1251748-32-9. Molecular formula: C12H18O3. Mole weight: 210.27. | |
| Vibralactone K | Vibralactone K is isolated from Boreostereum vibrans and has no cytotoxicity against five human cancer cell lines. Synonyms: 1H-Cyclopenta[c]furan-1-one, hexahydro-6-hydroxy-5-(3-methyl-2-buten-1-yl)-, (3aS,5S,6R,6aR)-. Grade: ≥98%. CAS No. 1623786-66-2. Molecular formula: C12H18O3. Mole weight: 210.27. | |
| Vibralactone L | Vibralactone L is isolated from Boreostereum vibrans and has no cytotoxicity against five human cancer cell lines. Synonyms: 3-Furanpropanoic acid, 2,5-dihydro-α-(3-methyl-2-buten-1-yl)-5-oxo-, ethyl ester, (+)-. Grade: ≥98%. CAS No. 1623786-67-3. Molecular formula: C14H20O4. Mole weight: 252.31. | |
| Vicanicin | Vicanicin is a depsidone isolated from the lichen Teloschistesflavicans (Sw.) Norm. Vicanicin can induce apoptosis of DU-145 and LNCaP cells. Synonyms: 2,7-Dichloro-3-hydroxy-8-methoxy-1,4,6,9-tetramethyl-11H-dibenzo[b,e][1,4]dioxepin-11-one. CAS No. 33211-22-2. Molecular formula: C18H16Cl2O5. Mole weight: 383.22. | |
| Vicenistatin | It is a macrocyclic lipid antibiotic produced by the strain of Str. sp. HC34. In vitro it is cytotoxic to human leukemia HL-60 cells and human colon cancer Co-LO205 cells with IC50 (μg/mL) of 0.12 and 0.19, respectively. Synonyms: Azacycloeicosa-3,5,10,13,15-pentaen-2-one, 7,11,13,19-tetramethyl-8-[[2,4,6-trideoxy-4-(methylamino)-β-D-ribo-hexopyranosyl]oxy]-, (3E,5E,7S,8S,10E,13E,15E,19S)-; Antibiotic HC34; NSC 641691; Vicenistatine. CAS No. 150999-05-6. Molecular formula: C30H48N2O4. Mole weight: 500.71. | |
| Vicenistatin M | It is produced by the strain of Streptomyces sp. HC-34. It is a homologue of Mycarose replacing amino sugars in the Vicenstatin molecule, and it loses the cytotoxicity of Vicenstatin. Synonyms: (6S,7S,18S)-20-aza-6,10,12,18-tetramethyl-7-O-(2',6'-dideoxy-3'-C-methyl-β-D-ribo-hexopyranosyl)-cycloicosa-2,4,9,12,14-pentaen-1-one; (3E,5E,10E,13E,15E)-(7S,8S,19S)-8-((2R,4S,5R,6R)-4,5-Dihydroxy-4,6-dimethyl-tetrahydro-pyran-2-yloxy)-7,11,13,19-tetramethyl-azacycloicosa-3,5,10,13,15-pentaen-2-one; Vicenistatine M. CAS No. 312532-50-6. Molecular formula: C30H47NO5. Mole weight: 501.70. | |
| Victoxinine | Victoxinine is a toxic metabolite of Helminthosporium victoriae. Synonyms: (4aalpha,8aalpha)-Decahydro-8-methyl-9-methylene-5beta-isopropyl-4beta,8beta-methanoisoquinoline-2-Ethanol; Victoxinin; 4,8-Methanoisoquinoline-2(1H)-Ethanol, octahydro-8-methyl-9-methylene-5-(1-methylethyl)-, (4R,4aR,5R,8R,8aS)-rel-(+)-. Grade: ≥98%. CAS No. 39965-06-5. Molecular formula: C17H29NO. Mole weight: 263.42. | |
| Vinaxanthone | It is a semaphorin inhibitor produced by the strain of Penicillinm sp. SPF-3059. It inhibits Semaphorin with IC50 of 0.1 μg/mL. Synonyms: Antibiotic 411F; Antibiotic Ro-09-1450; 9H-Xanthene-1-carboxylic acid, 5,7-diacetyl-6-(5-carboxy-6,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl)-2,3-dihydroxy-9-oxo-. CAS No. 133293-89-7. Molecular formula: C28H16O14. Mole weight: 576.42. | |
| Vinblastine | Vinblastine, an inhibitor of nAChR, is a natural alkaloid isolated from the plant Vinca rosea Linn. It binds to tubulin and inhibits microtubule formation, leading to disruption of mitotic spindle assembly and arrest of tumor cells in the M-phase of the cell cycle. It may also interfere with the metabolism of amino acids, cyclic AMP, and glutathione. It is used to treat malignant lymphoma. Uses: Antitumor. Synonyms: [3aR-[3aa,4b,5b,5ab,9(3R*,5S*,7R*,9S*),10bR*,13aa]]-Methyl 4-(acetyloxy)-3a-ethyl-9-[5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-1H-indolizino[8,1-cd]carbazole-5-carboxylate; 1H-Indolizino[8,1-cd]carbazole, vincaleukoblastine deriv.; 1H-Indolizino(8,1-cd)carbazole-5-carboxylic acid, 4-(acetyloxy)-3a-ethyl-9-(5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino(5,4-b)indol-9-yl)-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-, methyl ester, (3aR-(3aα,4β,5β,5aβ,9(3R*,5S*,7R*,9S*),10bR*,13aα))-; Rozevin; (+)-Vinblastine; Vincaleukoblastine. Grade: >98%. CAS No. 865-21-4. Molecular formula: C46H58N4O9. Mole weight: 810.97. | |
| Vinetorin | Vinetorin is a xanthone compound. Synonyms: Xanthen-9-one, 4-chloro-3,8-dihydroxy-6-methoxy-1-methyl- (8CI); 4-Chloro-3,8-dihydroxy-6-methoxy-1-methyl-9H-xanthen-9-one. CAS No. 23460-01-7. Molecular formula: C15H11ClO5. Mole weight: 306.7. | |
| Vinylamycin | It is a depsipeptide antibiotic produced by the strain of Streptomyces sp. M1982-63F1. It has activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 1.56-3.13 μg/mL. Synonyms: (8E,12S,15R)-3-(1-Methylheptyl)-4-(2-hydroxyethyl)-7-methylene-12-methyl-15-isopropyl-2-oxa-6,11,14-triazacyclopentadecane-8-ene-1,5,10,13-tetraone; 1-Oxa-4,7,12-triazacyclotetradec-9-ene-2,5,8,13-tetrone, 14-[1-(2-hydroxyethyl)-2-methyloctyl]-6-methyl-11-methylene-3-(1-methylethyl)-, (3R,6S,9E)-. CAS No. 224427-91-2. Molecular formula: C26H43N3O6. Mole weight: 493.64. | |
| Violaceol II | It is a mycotoxin isolated from Emericella violacea and Aspergillus spp. It has weak activity against Gram-positive bacteria, Gram-negative bacteria, fungi and yeast. Synonyms: violacerol-II; 3-(2,6-dihydroxy-4-methylphenoxy)-5-methylbenzene-1,2-diol; 5-methyl-2-[5-methyl-2,3-bis(oxidanyl)phenoxy]benzene-1,3-diol; 2-(2,3-dihydroxy-5-methyl-phenoxy)-5-methyl-resorcinol. CAS No. 81827-49-8. Molecular formula: C14H14O5. Mole weight: 262.26. | |
| Viomycin trihydrochloride | It is a peptide antibiotic produced by the strain of Str. puniceus 1314-5 and Str. floridae A5014. It has broad-spectrum antibacterial and strong anti-mycobacterium effect. 1-10 μg/mL of Viomycin can inhibit the growth of most tuberculosis bacilli, the main effect is to inhibit the protein synthesis of bacteria, but bacteria are prone to develop drug resistance. In clinical application, it is only used as a second-line drug to treat tuberculosis. Synonyms: Florimycin trihydrochloride; Viomycinum trihydrochloride; Vinacetin A trihydrochloride; Hexanamide, 3,6-diamino-N-[(3S,6Z,9S,12S,15S)-6-[[(aminocarbonyl)amino]methylene]-3-[(4R,6S)-2-amino-1,4,5,6-tetrahydro-6-hydroxy-4-pyrimidinyl]-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,1 3-pentaazacyclohexadec-15-yl]-, (3S)-, hydrochloride (1:3). CAS No. 39750-31-7. Molecular formula: C25H43N13O10.3HCl. Mole weight: 795.07. | |
| Vioxanthin | Vioxanthin is an antibiotic produced by Malbranchea pulchella var. sulfurea. It is active against gram-positive bacteria and bacteroides fragilis. Synonyms: Tf-26Vx. CAS No. 15447-05-9. Molecular formula: C30H26O10. Mole weight: 546.5. | |
| Viranamycin A | It is produced by the strain of Str. sp. CH 41. It can inhibit the growth of murine leukemia cell P388 with IC50 of 5.8 ng/mL, and it can also inhibit KB human multi-squamous cell carcinoma cells with IC50 of 6.4 ng/mL. Synonyms: Concanamycin A, 23-O-(3-carboxy-1-oxo-2-propenyl)-23-O-de[4-O-(aminocarbonyl)-2,6-dideoxy-b-D-arabino-hexopyranosyl]-25-de(1-propenyl)-25-methyl-. CAS No. 139595-03-2. Molecular formula: C41H64O13. Mole weight: 764.94. | |
| Viranamycin B | It is produced by the strain of Str. sp. CH 41. It can inhibit the growth of murine leukemia cell P388 with IC50 of 2.8 ng/mL, and it can also inhibit KB human multi-squamous cell carcinoma cells with IC50 of 1.9 ng/mL. Synonyms: Concanamycin A, 25-de(1-propenyl)-25-methyl-. CAS No. 139595-04-3. Molecular formula: C44H73NO14. Mole weight: 840.05. | |
| Virensic acid | It is a lichen acid with enzyme inhibitory potential. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 4-formyl-3,8-dihydroxy-1,6,9-trimethyl-11-oxo-; 10-formyl-3,9-dihydroxy-1,4,7-trimethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylic acid; Granulatine; NSC 685587. CAS No. 668-14-4. Molecular formula: C18H14O8. Mole weight: 358.30. | |
| Virginiamycin S2 | It is a depsipeptide antibiotic produced by the strain of Str. virginiae and Str. virginiae var. sp. It has anti-gram-positive bacteria and mycobacterium effects, and the antibacterial activity of component M of Virginiamycin against cocci is stronger than component S, while the activity is stronger than component M. Synonyms: Staphylomycin-S2; 4-L-Phenylalanine-5-(cis-4-hydroxy-L-2-piperidinecarboxylic acid)virginiamycin S1; N-[(3-Hydroxy-2-pyridinyl)carbonyl]cyclo[L-Thr*-D-Abu-L-Pro-L-Phe-[(4R)-4-hydroxy-L-pipecoloyl]-L-phenyl-Gly-]; N-[(3-Hydroxy-2-pyridyl)carbonyl]-cyclo[L-Thr*-D-Abu-L-Pro-L-Phe-4β-hydroxy-L-Hpr-L-phenyl-Gly-]. CAS No. 33477-38-2. Molecular formula: C42H49N7O10. Mole weight: 811.88. | |
| Virginiamycin S3 | It is a depsipeptide antibiotic produced by the strain of Str. virginiae and Str. virginiae var. sp. It has anti-gram-positive bacteria and mycobacterium effects, and the antibacterial activity of component M of Virginiamycin against cocci is stronger than component S, while the activity is stronger than component M. Synonyms: Staphylomycin S3; Virginiamycin S1, 5-(5-hydroxy-4-oxo-L-2-piperidinecarboxylic acid)-; N-[(3-Hydroxy-2-pyridinyl)carbonyl]cyclo[L-Thr*-D-Abu-L-Pro-N-methyl-L-Phe-4-oxo-5-hydroxy-L-pipecoloyl-L-phenyl-Gly-]. CAS No. 33477-39-3. Molecular formula: C43H49N7O11. Mole weight: 839.89. | |
| Viridicatol | Viridicatol is a fungal metabolite found in various Penicillium species as well as Phoma. It suppresses the expression of COX-2 and inducible nitric oxide synthase (iNOS) and inhibits production of nitric oxide and prostaglandin E2 (PGE2) in LPS-stimulated RAW 264.7 and BV2 cells. Synonyms: 2(1H)-Quinolinone, 3-hydroxy-4-(3-hydroxyphenyl)-; Carbostyril, 3-hydroxy-4-(m-hydroxyphenyl)-; 3-hydroxy-4-(3-hydroxyphenyl)carbostyril; 4-(3-Hydroxyphenyl)-2,3-quinolinediol. Grade: ≥95%. CAS No. 14484-44-7. Molecular formula: C15H11NO3. Mole weight: 253.25. | |
| Viridicatumtoxin | A tetracycline-like metabolite produced by several species of penicillium. It causes myocardial deterioration, renal tubule necrosis and spleen atrophy. It is a mycotoxin and a potent antibacterial with activity against S. Aureus including MRSA and QRSA strains. Synonyms: NSC 159628; viridicatumtoxin A; (1R,7'aR,11'aR,12'R)-rel-(-)-7',7'a,8',11',11'a,12'-hexahydro-5',6',7'a,10',11'a,12'-hexahydroxy-3'-methoxy-2,6,6-trimethyl-7',8'-dioxo-spiro[2-cyclohexene-1,2'(1'H)-cyclopenta[de]naphthacene]-9'-carboxamide; (2'α,7'aβ,11'aβ,12'β)-(-)-7',7'a,8',11',11'a,12'-Hexahydro-5',6',7'a,10',11'a,12'-hexahydroxy-3'-methoxy-2,6,6-trimethyl-7',8'-dioxo-spiro[2-cyclohexene-1,2'(1'H)-cyclopenta[de]naphthacene]-9'-carboxamide. Grade: >98% by HPLC. CAS No. 39277-41-3. Molecular formula: C30H31NO10. Mole weight: 565.57. | |
| Viridin | It is a steroidal antibiotic produced by the strain of Gliocladium virens. It has anti-fungal and gram-positive bacterial effects. Synonyms: (1S-(1alpha,2alpha,11balpha))-1,7,8,11b-Tetrahydro-1-hydroxy-2-methoxy-11b-methylcyclopenta(7,8)phenanthro(10,1-bc)furan-3,6,9(2H)-trione; 18-Norandrosta-5,8,11,13-tetraeno(6,5,4-bc)furan-3,7,17-trione, 1-hydroxy-2-methoxy-, (1beta,2beta)-; Cyclopenta(7,8)phenanthro(10,1-bc)furan-3,6,9(2H)-trione, 1,7,8,11b-tetrahydro-1-hydroxy-2-methoxy-11b-methyl-, (1S,2R,11bS)-. CAS No. 3306-52-3. Molecular formula: C20H16O6. Mole weight: 352.34. | |
| Viridomycin F | It is a viridomycin antibiotic produced by the strain of Streptomyces sp. K96-0188. It has weak insecticidal and nematocidal activity. It also has weak activity against Piricularia oryzae and Acholeplasma laidlawii. Synonyms: Antibiotic K 96-0188. CAS No. 221394-79-2. Molecular formula: C21H14N3O9Fe. Mole weight: 508.20. | |
| Vitamin B12 | Vitamin B12 is a water-soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Uses: Ingredient of health care products. Synonyms: 5,6-Dimethyl-1-(3-O-phosphono-α-D-ribofuranosyl)-1H-benzimidazole Monoester Cobinamide Cyanide Inner Salt; 5,6-Dimethylbenzimidazolyl Cyanocobamide; 5,6-Dimethylbenzimidazolyl-Co-cyanocobamide; Anacobin; Antipernicin; Apikobal; B-Twelve; B-Twelve Ora; Bedodeka; Bedoz; Behepan; Berubi; Berubigen; Dobetin; Docemine; Docibin; Poyamin; Rebramin; Redamina; Vitarubin; Vitral; Cyanocobalamin; Docigram; NSC 80365; NSC-80365; NSC80365; Norethisterone. Grade: >98%. CAS No. 68-19-9. Molecular formula: C63H88CoN14O14P. Mole weight: 1355.36. | |
| WA8242A | WA8242A is a PLA2 inhibitor consisting of A1 and A2. It is produced by Steptomyces violaceusniger No. 8242. Synonyms: WA-8242A. Molecular formula: C39H74N2O7. Mole weight: 683. | |
| WA8242B | WA8242B is a PLA2 inhibitor produced by Steptomyces violaceusniger No. 8242. Synonyms: WA-8242B. Molecular formula: C40H76N2O7. Mole weight: 697. | |
| Waol A | It is a trihydrofuran derivative with cytotoxicity produced by the strain of Myceliophthora lutea TF-0409. It has very weak anti-staphylococcus aureus activity. In cell culture, its cytoplasmic activity against HL 60, P388, T24, HeLa and A549 was 8-10 times weaker than adriamycin, but its cytoplasmic activity against HL 60/ADM was stronger than adriamycin (IC50 is 2.0 μg/mL). IC50 is 0.1 μg/mL. Synonyms: FD-211; NSC726144; NSC-726144; 5H-Furo[3,4-b]pyran-5-one, 2,3,7,7a-tetrahydro-3-hydroxy-2,7-di-(1E)-1-propen-1-yl-, (2R,3R,7S,7aR)-. Molecular formula: C13H16O4. Mole weight: 236.26. | |
| Waol B | It is a trihydrofuran derivative with cytotoxicity produced by the strain of Myceliophthora lutea TF-0409. It has very weak anti-staphylococcus aureus activity. In cell culture, its cytoplasmic activity against HL 60, P388, T24, HeLa and A549 was 8-10 times weaker than adriamycin, but its cytoplasmic activity against HL 60/ADM was stronger than adriamycin (IC50 is 2.0 μg/mL). IC50 is 0.2 μg/mL. Synonyms: FD-212; Propanoic acid, 3-[(2R,4S,5S)-dihydro-4-hydroxy-2,5-di-(1E)-1-propen-1-yl-3(2H)-furanylidene]-2-hydroxy-, methyl ester, (3E)-. Molecular formula: C14H20O5. Mole weight: 268.31. | |
| WAP-8294A II | WAP-8294A II is the main component of WAP-8294A, the anti-MRSA antibiotic isolated from the fermentation broth of Lysobacter sp. Synonyms: WAP-8294 A2. Molecular formula: C73H111N17O21. Mole weight: 1562.76. | |
| Watasemycin A | It is produced by the strain of Streptomyces sp. TP-A0597. It has anti-staphylococcus aureus, bacillus subtilis, proteus bizarre and cryptococcus neoformans activity with MIC (μg/mL) of 12.5, 25.0, 0.39 and 20.0, respectively. Synonyms: 4-Thiazolidinecarboxylic acid, 2-[(4R,5S)-4,5-dihydro-2-(2-hydroxyphenyl)-5-methyl-4-thiazolyl]-3,4-dimethyl-, (2S,4S)-. Molecular formula: C16H20N2O3S2. Mole weight: 352.47. | |
| Watasemycin B | It is produced by the strain of Streptomyces sp. TP-A0597. It has anti-staphylococcus aureus, bacillus subtilis, proteus bizarre and cryptococcus neoformans activity, but its antibacterial activity is lower than Watasemycin A. Synonyms: 4-Thiazolidinecarboxylic acid, 2-[(4R,5S)-4,5-dihydro-2-(2-hydroxyphenyl)-5-methyl-4-thiazolyl]-3,4-dimethyl-, (2R,4S)-. Molecular formula: C16H20N2O3S2. Mole weight: 352.47. | |
| WB-3559A | WB-3559A is a fibrinolytic metabolite produced by Flavobacterium sp. Synonyms: WB-3559 A; WB 3559 A. CAS No. 96053-97-3. Molecular formula: C36H66N2O7. Mole weight: 638.9. | |
| WB-3559B | WB-3559B is a fibrinolytic metabolite produced by Flavobacterium sp. Synonyms: WB-3559 B; WB 3559 B. CAS No. 96053-96-2. Molecular formula: C37H68N2O7. Mole weight: 652.9. | |
| WB-3559C | WB-3559C is a fibrinolytic metabolite produced by Flavobacterium sp. Synonyms: WB-3559 C; WB 3559 C. CAS No. 96095-05-5. Molecular formula: C36H68N2O7. Mole weight: 640.9. | |
| WB-3559D | WB-3559D is a fibrinolytic metabolite produced by Flavobacterium sp. Synonyms: WB-3559 D; WB 3559 D. CAS No. 96095-04-4. Molecular formula: C37H70N2O7. Mole weight: 655. | |
| WF-10129 | WF-10129 is an angiotensin converting enzyme (ACE) inhibitor produced by Doratomyces putredinis, with IC50 of 1.4 X 10(-8) M. Synonyms: WF 10129. CAS No. 109075-64-1. Molecular formula: C20H28N2O8. Mole weight: 424.4. | |
| WF11605 | WF11605 is an antagonist of leukotriene B4 (LTB4) isolated from the fungal strain F11605. It inhibited LTB4-induced chemotaxis of rabbit polymorphonuclear leukocytes (PMNLs) with an IC50 value of 1.7 x 10(-7) M and blocked 3H-LTB4 binding to PMNL membranes at 5.6 x 10(-6) M (IC50). It also inhibited LTB4-induced degranulation of rabbit PMNLs at 3.0 x 10(-6) M (IC50). Synonyms: WF 11605; WF-11605. CAS No. 127475-47-2. Molecular formula: C38H60O11. Mole weight: 692.9. | |
| WF11899A | WF11899A is a lipopeptide antibiotic isolated from the culture broth of Coleophoma empetri F-11899. It shows antifungal activity against Candida spp. Synonyms: WF-11899A. Molecular formula: C51H82N8O21S. Mole weight: 1175.3. | |
| WF11899B | WF11899B is a lipopeptide antibiotic isolated from the culture broth of Coleophoma empetri F-11899. It shows antifungal activity against Candida spp. Synonyms: WF-11899B. Molecular formula: C51H82N8O20S. Mole weight: 1159.3. | |
| WF11899C | WF11899C is a lipopeptide antibiotic isolated from the culture broth of Coleophoma empetri F-11899. It shows antifungal activity against Candida spp. Synonyms: WF-11899C. Molecular formula: C51H82N8O19S. Mole weight: 1143.3. | |
| WF-1360B | WF-1360B is one component of Rhizoxin complex produced by Rhizopus sp. No. F-1360. It was highly active against leukemia L1210 and melanoma B16. Synonyms: Antibiotic WF-1360B. Molecular formula: C34H45NO8. Mole weight: 595.72. | |
| WF-1360C | WF-1360C is one component of Rhizoxin complex produced by Rhizopus sp. No. F-1360. It was highly active against leukemia L1210 and melanoma B16. Synonyms: Antibiotic WF-1360C. Molecular formula: C34H45NO9. Mole weight: 611.72. | |
| WF-1360E | WF-1360E is one component of Rhizoxin complex produced by Rhizopus sp. No. F-1360. It was highly active against leukemia L1210 and melanoma B16. Synonyms: Antibiotic WF-1360E. Molecular formula: C37H53NO9. Mole weight: 655.82. | |
| WF-1360F | WF-1360F is one component of Rhizoxin complex produced by Rhizopus sp. No. F-1360. It was highly active against leukemia L1210 and melanoma B16. Synonyms: Antibiotic WF-1360F. Molecular formula: C35H47NO8. Mole weight: 609.75. | |
| WF14861 | WF14861 is a cathepsins B and L inhibitor obtained from the culture mycelium of a fungus strain Colletotrichum sp. No. 14861. Synonyms: WF 14861; WF-14861. Molecular formula: C20H30N4O6. Mole weight: 422.5. | |
| WF14865A | WF14865A is a cathepsins B and L inhibitor with IC50 of 8.4 X 10(-9) and 6.6 X 10(-8) mol/L, respectively. It is produced by Aphanoascus fulvescens. Synonyms: WF-14865A. Molecular formula: C16H25N5O5. Mole weight: 367.4. | |
| WF14865B | WF14865B is a cathepsins B and L inhibitor with IC50 of 1.3 X 10(-8) and 7.2 X 10(-8) mol/L, respectively. It is produced by Aphanoascus fulvescens. Synonyms: WF-14865B. Molecular formula: C17H27N5O5. Mole weight: 381.43. | |
| WF-2421 | WF-2421 is an aldose reductase inhibitor produced by Humicola grisea. Synonyms: WF 2421. CAS No. 128429-19-6. Molecular formula: C19H20N2O8. Mole weight: 404.4. | |
| WF-3161 | WF-3161 is an antitumor antibiotic produced by a strain of fungus, Petriella guttulata. It inhibited the growth of Trichophyton asteroides. Synonyms: Antibiotic WF 3161; WF 3161; Antibiotic FR 900261; WF-3161. CAS No. 86402-37-1. Molecular formula: C31H44N4O6. Mole weight: 568.7. | |
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