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YN-0165J-A
YN-0165J-A is an enteromycin group antibiotic produced by Streptomyces strain YN-0165J. It is effective against Gram-positive and -negative bacteria, but is inactive to Enterobacter cloacae and Pseudomonas aeruginosa. CAS No. 102692-05-7. Molecular formula: C7H13N3O4. Mole weight: 203.2.
Yokonolide A
It is produced by the strain of Streptomyces diastatochromogenes B59. It can inhibit the signal transduction of thaliphin. Synonyms: (1S,4E,6R,6'R,7S,8R,9R,10R,11S,12S,16E,18S,19S,21S,23R,25R)-6,7,9,11,19-Pentahydroxy-6'-[(2R)-2-hydroxybutyl]-18-[(2S)-3-hydroxy-2-methylpropyl]-6,8,12,25-tetramethyl-3-oxo-3',4',5',6'-tetrahydrospiro[2,22-dioxabicyclo[19.3.1]pentacosa-4,16-diene-23,2'-pyran]-10-yl 2,4,6-trideoxy-4-(dimethylamino)-alpha-L-lyxo-hexopyranoside. Molecular formula: C47H83NO14. Mole weight: 886.16.
YS-822A
YS-822A is a polyene macrolide antibiotic isolated from the culture filtrate of a mutant strain H-8 of Streptoverticillium eurocidicum var. asterocidicus S-822. It has antifungal activity with MIC of 3.12-12.5μg/mL for yeast. Synonyms: YS 822A; Antibiotic YS 822A; 10,29-Dioxabicyclo(23.3.1)nonacosa-15,17,19,21-tetraene-26-carboxylic acid, 23-((3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy)-1,3,5,6,27-pentahydroxy-11-(1-methylethyl)-9-oxo-. CAS No. 130767-46-3. Molecular formula: C37H59NO14. Mole weight: 741.9.
YUA001
YUA001 is an aldose reductase inhibitor produced from alkalophilic Corynebacterium sp. YUA25. It has no antimicrobial activity. Synonyms: YUA-001. Molecular formula: C13H19NO2. Mole weight: 221.29.
Z-β-alanine has been utilized for various synthesis applications including palladium-catalyzed asymmetric allylation of β-diketones, branched linker that can increase the potency of doxorubicin immunoconjugates, and diacridines that intercalate nucleic acids and inhibit DNA synthesis. Synonyms: Z-β-Ala-OH; 3-Z-aminopropanoic acid; Z-beta-Ala-OH; carbobenzyloxy-beta-alanine; N-Cbz-beta-alanine; Cbz-beta-alanine; N-Benzyloxycarbonyl-beta-alanine; Cbz-beta-Ala-OH; N-Carbobenzoxy-beta-alanine; 3-(benzyloxycarbonylamino)propanoic acid; 3-{[(benzyloxy)carbonyl]amino}propanoic acid; Z beta Ala OH; Cbz beta Ala OH. Grade: ≥ 99% (HPLC). CAS No. 2304-94-1. Molecular formula: C11H13NO4. Mole weight: 223.20.
Z-β-alanine amide
Z-β-alanine amide. Synonyms: Z-β-Ala-NH2; 3-Z-aminopropionamide; benzyl N-(2-carbamoylethyl)carbamate; Z-BETA-ALA-NH2; Z-beta-alanine amide; benzyl N-(3-amino-3-oxopropyl)carbamate; Benzyloxycarbonyl-beta-alaninamide; Z BETA ALA NH2. Grade: ≥ 99% (HPLC). CAS No. 886-64-6. Molecular formula: C11H14N2O3. Mole weight: 222.24.
A minor component of the zearalenone complex produced by several species of fusarium. Zearalanone is an estrogen receptor agonist (EC50 = 0.11 μM). Synonyms: (S)-Zearalanone; P 1502; Zanone. Grade: >99% by HPLC. CAS No. 5975-78-0. Molecular formula: C18H24O5. Mole weight: 320.38.
Zearalenone
Zearalenone is a mycotoxin produced by Fusarium. The 100 ppm acetonitrile solution of Zearalenone, a kind of natural estrogen, could be used as standard solution. Uses: Estrogens, non-steroidal. Synonyms: (3S,11E)-3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2 -benzoxacyclotetradecin-1,7(8H)-dione; (-)-Zearalenone; Mycotoxin F 2; Toxin F2; Zenone; trans-Zearalenone. CAS No. 17924-92-4. Molecular formula: C18H22O5. Mole weight: 318.37.
Zerbaxa (Ceftolozane/tazobactam)
Zerbaxa (Ceftolozane/tazobactam), a combination product consisting of a cephalosporin-class antibacterial drug and a beta-lactamase inhibitor, is a combination antibiotic medication used for the treatment of complicated urinary tract infections and complicated intra-abdominal infections in adults. Synonyms: Ceftolozane-tazobactam mixt.; CXA 201 sulfate-tazobactam mixt.; 1H-Pyrazolium, 5-amino-4-[[[(2-aminoethyl)amino]carbonyl]amino]-2-[[(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, inner salt, mixt. with (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide. CAS No. 1613740-46-7. Molecular formula: C23H30N12O8S2.C10H12N4O5S. Mole weight: 966.98.
Zg
Zg is a red quinone piment produced from Streptomyces Thermoviolaceus sub sp. pigens var WR-141. Molecular formula: C22H18O8. Mole weight: 410.4.
ZG-1494α
ZG-1494α is a platelet-activating factor (PAF) acetyltransferase inhibitor, which is isolated from an ethyl acetate extract of a culture broth of Penicillium rubrum through bioassay guided fractionation. Synonyms: Talaroconvolutin B; ZG-1494alpha. Molecular formula: C32H43NO4. Mole weight: 505.7.
Zgg is a red quinone piment produced from Streptomyces Thermoviolaceus sub sp. pigens var WR-141. CAS No. 63972-29-2. Molecular formula: C22H16O8. Mole weight: 408.4.
Z-Leu-Arg-7-Amino-4-Methylcoumarin is a fluorescent substrate for cathepsin L, S, and V, human tissue kallikrein and the falcipains I-III. It is the preferred substrate for falcipain II, a hemoglobin-degrading cysteine protease from Plasmodium falciparum, one of the most promising targets for antimalarial drug design. It is used to detect cathepsin K, an enzyme involved in osteoclast bone resorption. Synonyms: Z-LR-AMC; Cbz-Leu-Arg-AMC; Cathepsin K Substrate (fluorogenic); benzyloxycarbonyl-Leu-Arg-7-amino-4-methyl-coumarin; benzyl (S)-1-((S)-5-guanidino-1-(4-methyl-2-oxo-2H-chromen-7-ylamino)-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-ylcarbamate; L-Argininamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; Benzyloxycarbonyl-L-leucyl-L-arginine 4-methylcoumaryl-7-amide. Grade: 99%. CAS No. 156192-32-4. Molecular formula: C30H38N6O6. Mole weight: 578.66.
Z-Leu-Arg-Gly-Gly-AMC
Z-Leu-Arg-Gly-Gly-AMC is a fluorescent substrate based on the C-terminal isopeptidase T (IPaseT) of ubiquitin and other ubiquitin C-terminal hydrolases (UCH). Synonyms: Z-LRGG-AMC.TFA; UCH Substrate. Grade: >95%. CAS No. 167698-68-2. Molecular formula: C36H45F3N8O10. Mole weight: 692.77.
Z-Leu-Leu-OH. Synonyms: Z-L-leucyl-L-leucine; N-Carbobenzoxy-L-leucyl-L-leucine; (S)-2-((S)-2-(((Benzyloxy)Carbonyl)Amino)-4-Methylpentanamido)-4-Methylpentanoic Acid; Z Leu Leu OH. Grade: ≥ 95% (HPLC). CAS No. 7801-71-0. Molecular formula: C20H30N2O5. Mole weight: 378.47.
Z-Leu-Leu-Tyr-α-keto aldehyde
Z-Leu-Leu-Tyr-α-keto aldehyde, an excellent inhibitor of serine and cysteine proteases, is an excellent inhibitor of chymotryptic-like activity of the proteasome with a Ki of about 3.0 nM. It may be valuable in identifying the role of the proteasome in the normal and abnormal pathways of protein catabolism in cells. Synonyms: L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-[(4-hydroxyphenyl)methyl]-2,3-dioxopropyl]-; Z-LLY-α-keto aldehyde; N-[(Benzyloxy)carbonyl]-L-leucyl-N-[(2S)-1-(4-hydroxyphenyl)-3,4-dioxo-2-butanyl]-L-leucinamide; benzyl ((S)-1-(((S)-1-(((S)-1-(4-hydroxyphenyl)-3,4-dioxobutan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)carbamate; Cbz-Leu-Leu-Tyr-α-keto aldehyde. Grade: ≥95%. CAS No. 204649-66-1. Molecular formula: C30H39N3O7. Mole weight: 553.66.
Z-Leu-Phe-OH
Substrate for carboxypeptidase Y from baker's yeast. Synonyms: Z-L-leucyl-L-phenylalanine; (S)-2-((S)-2-(benzyloxycarbonylamino)-4-methylpentanamido)-3-phenylpropanoic acid; Z Leu Phe OH. Grade: ≥ 99% (HPLC). CAS No. 6401-63-4. Molecular formula: C23H28N2O5. Mole weight: 412.49.
Z-Leu-Trp-OH
Z-Leu-Trp-OH. Synonyms: Z-L-leucyl-L-tryptophan; (S)-2-((S)-2-(benzyloxycarbonylamino)-4-methylpentanamido)-3-(1H-indol-3-yl)propanoic acid; Z Leu Trp OH. Grade: ≥ 99% (TLC). CAS No. 53262-00-3. Molecular formula: C25H29N3O5. Mole weight: 451.52.
Z-Leu-Tyr-chloromethylketone
Z-Leu-Tyr-chloromethylketone is an E.coli ClpP inhibitor. Synonyms: Carbobenzyloxyleucyl-tyrosine chloromethyl ketone; Z-LY-CMK; 2-{[(Benzyloxy)(hydroxy)methylidene]amino}-N-[4-chloro-1-(4-hydroxyphenyl)-3-oxobutan-2-yl]-4-methylpentanimidic acid. CAS No. 56979-35-2. Molecular formula: C24H29ClN2O5. Mole weight: 460.95.