BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| TMC-171C | TMC-171C is a polyketide antibiotic produced by Gliocladium sp. TC 1304. It has cytotoxicity to cancer cells like HCT-1l6, H-60, U937, WiDr. Synonyms: TMC-171 C. Molecular formula: C41H72O15. Mole weight: 805. |  |
| TMC-1A | TMC-1A is a Manumycin-associated antibiotic produced by Streptomyces sp. A-230. It has activity against gram-positive bacteria and cytotoxicity to various cancer cells. Synonyms: TMC-1 A. Molecular formula: C28H36N2O7. Mole weight: 512.6. | |
| TMC-1B | TMC-1B is a Manumycin-associated antibiotic produced by Streptomyces sp. A-230. It has activity against gram-positive bacteria and cytotoxicity to various cancer cells. Synonyms: TMC-1 B. Molecular formula: C28H36N2O7. Mole weight: 512.6. | |
| TMC-1C | TMC-1C is a Manumycin-associated antibiotic produced by Streptomyces sp. A-230. It has activity against gram-positive bacteria and cytotoxicity to various cancer cells. Synonyms: TMC-1 C. Molecular formula: C30H38N2O7. Mole weight: 538.6. | |
| TMC-1D | TMC-1D is a Manumycin-associated antibiotic produced by Streptomyces sp. A-230. It has activity against gram-positive bacteria and cytotoxicity to various cancer cells. Synonyms: TMC-1 D. Molecular formula: C30H40N2O7. Mole weight: 540.6. | |
| TMC-256A1 | TMC-256A1 is an inhibitor of IL-4 signal transduction isolated from the fermentation broth of Aspergillus niger var niger TC 1629. It inhibited the IL-4 driven luciferase activity with IC50 values of 25 μmol/L. Synonyms: TMC-256 A1. CAS No. 3773-18-0. Molecular formula: C15H12O5. Mole weight: 272.25. | |
| TMC-256C1 | TMC-256C1 is an inhibitor of IL-4 signal transduction isolated from the fermentation broth of Aspergillus niger var niger TC 1629. It inhibited the IL-4 driven luciferase activity with IC50 values of 1.7 μmol/L. Synonyms: TMC-256 C1. Molecular formula: C15H12O5. Mole weight: 272.25. | |
| TMC-260 | TMC-260 is an inhibitor of IL-4 signal transduction produced by Acremonium kiliense Grütz TC 1703. It inhibited the IL-4 driven luciferase activity with IC50 values of 9 μmol/L. Synonyms: TMC 260. Molecular formula: C17H27NO5. Mole weight: 325.4. | |
| TMC-264 | TMC-264 is a STAT6 activation inhibitor produced by Phoma sp. TC 1674. It suppressed expression of IL-4 driven luciferase and germline Cepsilon mRNA with IC50 values of 0.3 and 0.4 μmol/L, respectively, and inhibited tyrosine phosphorylation of STAT6 with an IC50 value of 1.6 μmol/L. Synonyms: TMC 264. Molecular formula: C16H13ClO7. Mole weight: 352.72. | |
| TMC-2A | TMC-2A is a dipeptidyl peptidase IV (DPIV) inhibitor isolated from the fermentation broth of Aspergillus oryzae A374. It inhibited rat kidney DPIV with IC50 value of 8.1 μmol/L. Synonyms: TMC-2 A. Molecular formula: C28H34N4O9. Mole weight: 570.6. | |
| TMC-2B | TMC-2B is a dipeptidyl peptidase IV (DPIV) inhibitor isolated from the fermentation broth of Aspergillus oryzae A374. It inhibited rat kidney DPIV with IC50 value of 8.1 μmol/L. Synonyms: TMC-2 B. Molecular formula: C28H34N4O8. Mole weight: 554.6. | |
| TMC-2C | TMC-2C is a dipeptidyl peptidase IV (DPIV) inhibitor isolated from the fermentation broth of Aspergillus oryzae A374. It inhibited rat kidney DPIV with IC50 value of 8.1 μmol/L. Synonyms: TMC-2 C. Molecular formula: C28H34N4O8. Mole weight: 554.6. | |
| TMC-34 | TMC-34 is an macrolide antifungal antibiotic produced by Streptomyces sp. A-3030. Synonyms: TMC 34. Molecular formula: C54H93N3O17. Mole weight: 1056.3. | |
| TMC-49A | TMC-49A is a transcriptional up-regulator of low density lipoprotein receptor. It is produced by Streptomyces sp. AS1345. It enhanced the synthesis of LDL receptor in human hepatoma HepG2 cells as assessed by a receptor binding assay. Synonyms: TMC-49 A; 2-phenylethyl n-butyl carbamate. Molecular formula: C13H19NO2. Mole weight: 221.29. | |
| TMC-52A | TMC-52A is a cysteine proteinase inhibitor produced by Gliocladium sp. F-2665. It strongly inhibited cysteine proteinases, in particular, cathepsin L with IC50 value of 13 nM. Synonyms: TMC-52 A. Molecular formula: C20H30N4O6. Mole weight: 422.5. | |
| TMC-52B | TMC-52B is a cysteine proteinase inhibitor produced by Gliocladium sp. F-2665. It strongly inhibited cysteine proteinases, in particular, cathepsin L with IC50 value of 10 nM. Synonyms: TMC-52 B. Molecular formula: C20H30N4O6. Mole weight: 422.5. | |
| TMC-52C | TMC-52C is a cysteine proteinase inhibitor produced by Gliocladium sp. F-2665. It strongly inhibited cysteine proteinases, in particular, cathepsin L with IC50 value of 10 nM. Synonyms: TMC-52 C. Molecular formula: C20H30N4O5. Mole weight: 406.5. | |
| TMC-52D | TMC-52D is a cysteine proteinase inhibitor produced by Gliocladium sp. F-2665. It strongly inhibited cysteine proteinases, in particular, cathepsin L with IC50 value of 6 nM. Synonyms: TMC-52 D. Molecular formula: C20H30N4O5. Mole weight: 406.5. | |
| TMC-66 | TMC-66 is a selective endothelin conversion enzyme (ECE) inhibitor isolated from the culture broth of Streptomyces sp. A5008. Synonyms: TMC 66. Molecular formula: C29H21NO9. Mole weight: 527.5. | |
| TMC-69 | TMC-69 is an antitumor antibiotic isolated from the fermentation broth of a fungal strain Chrysosporium sp. TC 1068. It exhibited moderate in vitro cytotoxic activity. Synonyms: TMC 69. Molecular formula: C26H31NO4. Mole weight: 421.5. | |
| TMC-86A | TMC-86A is a 20S proteasome inhibitor isolated from the fermentation broth of Streptomyces sp. A5008. It inhibited the chymotrypsin-like and peptidylglutamyl-peptide hydrolyzing activities of 20S proteasome with IC50 values of 5.1 and 3.7 μmol/L, respectively. Synonyms: TMC-86 A. Molecular formula: C16H26N2O6. Mole weight: 342.39. | |
| TMC-86B | TMC-86B is a 20S proteasome inhibitor isolated from the fermentation broth of Streptomyces sp. A5008. It inhibited the chymotrypsin-like and peptidylglutamyl-peptide hydrolyzing activities of 20S proteasome with IC50 values of 1.1 and 31 μmol/L, respectively. Synonyms: TMC-86 B. Molecular formula: C20H34N2O7. Mole weight: 414.5. | |
| TMC-89A | TMC-89A is a 20S proteasome inhibitor produced by streptomyces sp. TC 1087. It inhibited chymotrypsin-like (ChT-L), trypsin-like (T-L), and peptidylglutamyl-peptide hydrolyzing (PGPH) activities of 20S proteasome with IC50 of 1.1, 0.39 and 7.2 μmol/L, respectively. Synonyms: TMC-89 A; N-[(2R)-3-amino-2-methyl-3-oxopropanoyl]-L-threonyl-N-{1-[2-(hydroxymethyl)oxiran-2-yl]-4-methyl-1-oxopentan-2-yl}-L-threoninamide. Molecular formula: C21H36N4O9. Mole weight: 488.5. | |
| TMC-89B | TMC-89B is a 20S proteasome inhibitor produced by streptomyces sp. TC 1087. It inhibited chymotrypsin-like (ChT-L), trypsin-like (T-L), and peptidylglutamyl-peptide hydrolyzing (PGPH) activities of 20S proteasome with IC50 of 1.1, 0.51 and 7.1 μmol/L, respectively. Synonyms: TMC-89 B; N-[(2S)-3-amino-2-methyl-3-oxopropanoyl]-L-threonyl-N-{1-[2-(hydroxymethyl)oxiran-2-yl]-4-methyl-1-oxopentan-2-yl}-L-threoninamide. Molecular formula: C21H36N4O9. Mole weight: 488.5. | |
| TMC-95A | TMC-95A is a proteasome inhibitor produced by Apiospora montagnei Sacc. TC 1093. It inhibited the chymotrypsin-like (ChT-L), trypsin-like (T-L), and peptidylglutamyl-peptide hydrolyzing (PGPH) activities of 20S proteasome with IC50 values of 5.4nM, 200nM, and 60nM, respectively. Synonyms: TMC-95 A. CAS No. 220666-21-7. Molecular formula: C33H38N6O10. Mole weight: 678.7. | |
| TMC-95B | TMC-95B is a proteasome inhibitor produced by Apiospora montagnei Sacc. TC 1093. It inhibited the chymotrypsin-like (ChT-L), trypsin-like (T-L), and peptidylglutamyl-peptide hydrolyzing (PGPH) activities of 20S proteasome to the same extent as TMC-95A. Synonyms: TMC-95 B. Molecular formula: C33H38N6O10. Mole weight: 678.7. | |
| TMC-95C | TMC-95C is a proteasome inhibitor produced by Apiospora montagnei Sacc. TC 1093. Synonyms: TMC-95 C. Molecular formula: C33H38N6O10. Mole weight: 678.7. | |
| TMC-95D | TMC-95D is a proteasome inhibitor produced by Apiospora montagnei Sacc. TC 1093. Synonyms: TMC-95 D. Molecular formula: C33H38N6O10. Mole weight: 678.7. | |
| TMC-96 | TMC-96 is a proteasome inhibitor produced by Saccharothrix sp. TC 1094. It inhibited the chymotrypsin-like and peptidylglutamyl-peptide hydrolyzing activities of 20S proteasome with IC50 values of 2.9 and 3.5 μmol/L, respectively. Synonyms: TMC 96. Molecular formula: C18H32N2O6. Mole weight: 372.5. | |
| Tolypomycin R | Tolypomycin R is produced by the strain of Str. tolypophorus B2847. It has a broad-spectrum antimicrobial effect, which protects mice infected with gram-positive bacteria, and also has an inhibitory effect on vaccine virus. Synonyms: B-2847-R; L-erythro-Hexopyranose, 2,3,4,6-tetradeoxy-4-((5,6,11,12,13,14,15,16,16a,17,17a,18,21,22-tetradecahydro-2,12,14,16,26-pentahydroxy-10-methoxy-3,6,11,13,15,20-hexamethyl-5,18,21-trioxo-10H-4,6-epoxy-1,23-methenobenzo(d)cycloprop(n)(1,9)oxaazacyclotetracosin-25-yl)amino)-, 12-acetate. Grade: >98%. CAS No. 33889-22-4. Molecular formula: C43H56N2O14. Mole weight: 824.91. | |
| Tolypomycin Y | Tolypomycin Y is produced by the strain of Str. tolypophorus B2847. It has a broad-spectrum antimicrobial effect, which protects mice infected with gram-positive bacteria, and also has an inhibitory effect on vaccine virus. Synonyms: NSC-177383; Tolypromycin Y. Grade: 96%. CAS No. 23412-26-2. Molecular formula: C43H54N2O14. Mole weight: 822.89. | |
| Topopyrone A | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone A selectively inhibits topoisomerase I with the IC50 of 1.22 ng/mL. It also has anti-Gram-positive bacteria activity. Molecular formula: C18H9ClO7. Mole weight: 372.71. | |
| Topopyrone B | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone B selectively inhibits topoisomerase I with the IC50 of 0.15 ng/mL. It also has anti-Gram-positive bacteria activity and it has a strong inhibitory effect on herpes virus, especially varicella zoster virus (VZV). Molecular formula: C18H9ClO7. Mole weight: 372.71. | |
| Topopyrone C | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone C selectively inhibits topoisomerase I with the IC50 of 4.88 ng/mL. It also has anti-Gram-positive bacteria activity. Molecular formula: C18H10O7. Mole weight: 338.27. | |
| Topopyrone D | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone A selectively inhibits topoisomerase I with the IC50 of 19.63 ng/mL. Molecular formula: C18H10O7. Mole weight: 338.27. | |
| Topostatin | Topostatin is originally isolated from Thermomonos pora alba No. 1520. It has inhibitory effects on human tumor cells, and the IC50 of SNB-75 and SNB-78 were 0.4 μmol/L and 7 μmol/L, respectively. Molecular formula: C36H58N4O11S. Mole weight: 754.93. | |
| Torreyanic acid | Torreyanic acid is a dimer quinone obtained from the endophytic bacterium Pestalotiopsis microspora. Torreyanic acid is cytotoxic to tumor cells and is 5-10 times more effective in cell lines sensitive to protein kinase C agonists. CAS No. 176260-42-7. Molecular formula: C38H44O12. Mole weight: 692.75. | |
| TPU-0031-A | TPU-0031-A is an antibiotic of the novobiocin group produced by Streptomyces sp. TP-A0556. It shows antibiotic activity against Gram-positive and -negative bacteria. Molecular formula: C30H34N2O11. Mole weight: 598.6. | |
| TPU-0031-B | TPU-0031-B is an antibiotic of the novobiocin group produced by Streptomyces sp. TP-A0556. It shows antibiotic activity against Gram-positive and -negative bacteria. Molecular formula: C30H34N2O11. Mole weight: 598.6. | |
| TPU-0037B | TPU-0037B is a lydicamycin congener with anti-MRSA activity isolated from a culture broth of an actinomycete strain. It is closely related to BN 4515N which was isolated from a strain of microtetraspora as a neuritogenic agent. Synonyms: TPU-0037 B. Molecular formula: C47H72N4O9. Mole weight: 837.09. | |
| TPU-0037D | TPU-0037D is a lydicamycin congener with anti-MRSA activity isolated from a culture broth of an actinomycete strain. It is closely related to BN 4515N which was isolated from a strain of microtetraspora as a neuritogenic agent. Synonyms: TPU-0037 D. Molecular formula: C47H74N4O9. Mole weight: 839.11. | |
| Trametol | Trametol is produced from the culture medium of Bjerkandera sp. BOS55. Synonyms: 1,2-Propanediol, 1-(3-chloro-4-methoxyphenyl)-, (1R,2S)-. Grade: ≥98%. CAS No. 169217-47-4. Molecular formula: C10H13ClO3. Mole weight: 216.66. | |
| trans-4-Hydroxymellein | It is produced by the strain of Apiospora camptospora and marine-derived Microsphaeropsis sp. H5-50. It is the constituent of Moringa oleifera (horseradish tree) and Septoria nodorum. Synonyms: 1H-2-Benzopyran-1-one, 3,4-dihydro-4,8-dihydroxy-3-methyl-, (3R,4S)-; (3R,4S)-hydroxymellein; (3R,4S)-4,8-dihydroxy-3-methylisochroman-1-one; 1H-2-Benzopyran-1-one, 3,4-dihydro-4,8-dihydroxy-3-methyl-, (3R-trans)-; (-)-trans-4-hydroxymellein. CAS No. 70287-70-6. Molecular formula: C10H10O4. Mole weight: 194.18. | |
| Transplatin | The less-active isomer of the DNA damanging, platinum antitumor drug cisplatin. Transplatin is used in the treatment of a variety of solid tumors. Transplatin's anti-tumor activity can be activated by light. Synonyms: Trans-Dichlorodiamineplatinum(II); Azane; Cisplatin. CAS No. 14913-33-8. Molecular formula: Cl2H6N2Pt. Mole weight: 300.05. | |
| Trehalosamine | Trehalosamine is a carbohydrate antibiotic originally isolated from Str. sp. It has anti-gram-positive bacteria and Pseudomonas aeruginosa and mycobacterium action. Synonyms: 2-Trehalosamine; 2-amino-2-deoxy-alpha-D-glucopyranosyl alpha-D-glucopyranoside; alpha-D-Glucopyranosyl 2-amino-2-deoxy-alpha-D-glucopyranoside. CAS No. 27208-79-3. Molecular formula: C12H23NO10. Mole weight: 341.31. | |
| Trestatin A | It is produced by the strain of Str. dimorphogenes NR-320-OM7HB. Trestatin A has a strong inhibitory effect on pancreatic α-amylase, and also inhibits the α-amylase of Bacillus subtilis and Aspergillus oryzae. Synonyms: Ro 09-0183. CAS No. 71884-70-3. Molecular formula: C56H94N2O40. Mole weight: 1435.33. | |
| Trestatin B | It is produced by the strain of Str. dimorphogenes NR-320-OM7HB. Trestatin B has a strong inhibitory effect on pancreatic α-amylase, and also inhibits the α-amylase of Bacillus subtilis and Aspergillus oryzae. Synonyms: Ro 09-0184; alpha-D-Glucopyranoside, alpha-D-glucopyranosyl O-4,6-dideoxy-4-((4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl)amino)-alpha-D-glucopyranosyl-(1-4)-O-alpha-D-glucopyranosyl-(1-4)-O-alpha-D-glucopyranosyl-(1-4)-, (1S-(1-alpha,4-alpha,5-beta,6-alpha))-. CAS No. 71869-92-6. Molecular formula: C37H63NO28. Mole weight: 969.88. | |
| Trestatin C | It is produced by the strain of Str. dimorphogenes NR-320-OM7HB. Trestatin C has a strong inhibitory effect on pancreatic α-amylase, and also inhibits the α-amylase of Bacillus subtilis and Aspergillus oryzae. Synonyms: Ro 09-0185. CAS No. 71892-68-7. Molecular formula: C75H125N3O52. Mole weight: 1900.78. | |
| Triacetylphloroglucinol | It is the most hydrophobic of a small molecular weight phenolic metabolite belonging to the phloroglucinol (1,3,5 trihydroxybenzene) family. It is produced by pseudomonas fluoresces and exhibits a broad range of biological activities. It is important for dereplication to eliminate leads due to high amounts of weakly potent actives. Synonyms: Phloroglucinol 2,4,6-Triacetate; 2,4,6-Triacetyl-1,3,5-trihydroxybenzene; 2,4,6-Triacetylphloroglucinol; 1,1',1''-(2,4,6-Trihydroxybenzene-1,3,5-triyl)triethanone. Grade: >98% by HPLC. CAS No. 2161-87-7. Molecular formula: C12H12O6. Mole weight: 252.22. | |
| Triacsin C | Triacsin C, originally isolated from Streptomyces sp., is a polyunsaturated fatty acid derivative. It has been found to be an acyl-CoA synthetase inhibitor as well as an effective vasodilator. It selectively inhibits arachidonoyl-CoA synthetase in intact cells and the nonspecific acyl-CoA synthetase in cell sonicates, as well as inhibits neutrophil functions. Synonyms: 2E,4E,7E-Undecatriene-1-triazene; WS 1228A; 1-Hydroxy-3-(2',4',7'-undecatrienylidine)triazene. Grade: ≥95%. CAS No. 76896-80-5. Molecular formula: C11H17N3O. Mole weight: 207.30. | |
| Trichodermin | Trichodermin is a terpenoid antibiotic which has anti-fungal and protozoal effects. It is originally isolated from Trichoderma viride. Synonyms: Trichoderonin; NSC 73846; 12,13-Epoxytrichothec-9-en-4-ol acetate; [(2S)-trimethylspiro[[?]-2,2'-oxirane]yl] acetate. Grade: 99%. CAS No. 4682-50-2. Molecular formula: C17H24O4. Mole weight: 292.37. | |
| Trichodimerol | BMS-182123 is a substance produced by Penicillum chrysogenum V39673 that can inhibit the production of Tumor necrosis factor (TNF-a). The IC50 of inhibiting lipopolysaccharide (LPS) induced TNF-a in murine macrophages and human monocytes were 600 ng/mL and 4.0 μg/mL, respectively. Synonyms: BMS-182123. CAS No. 145174-90-9. Molecular formula: C28H32O8. Mole weight: 496.55. | |
| Trichodion | Trichodion is originally isolated from Trichosporiella sp. It inhibits the expression of secretion alkaline phosphatase (SEAP) Reporter gene mediated by IFN-V with IC50 of 5-10 μg/mL, and it also inhibits the expression of human IFN-α promoter-driven Luciferase Reporter gene with IC50 of 2.5-5μg/mL. Molecular formula: C12H14O5. Mole weight: 238.24. | |
| Trichostatin D | Trichostatin D is a metamorphosis cell phenotype recovery inducer produced by the strain of Streptomyces violaceusniger. Synonyms: 1-O-({(2E,4E,6R)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxohepta-2,4-dienoyl}amino)-alpha-D-glucopyranose. CAS No. 157479-37-3. Molecular formula: C23H32N2O8. Mole weight: 464.51. | |
| Trichostatin RK | Trichostatin RK is a trigustatine derivative produced by the strain of Streptomyces sp. RK98-A74. It can induce luciferase, but its activity is lower than that of trigustatin. Molecular formula: C18H24N2O2. Mole weight: 300.39. | |
| Trichothecin | Trichothecin has anti-fungal and protozoal effects and it's produced by the strain of Trichothecium roseum. Synonyms: NSC 92492; 12,13-Epoxy-4-hydroxytrichothec-9-en-8-one crotonate. CAS No. 6379-69-7. Molecular formula: C19H24O5. Mole weight: 332.39. | |
| Trichoviridin | It is originally isolated from Trichoderma viride. Trichoviridin has anti-bacterial and fungal effects. Synonyms: Isonitrin C; Trichoviridine. CAS No. 56283-32-0. Molecular formula: C8H9NO4. Mole weight: 183.16. | |
| Triclosan | Triclosan is a broad-spectrum antibacterial and antifungal agent added in consumer products such as toothpaste, soaps, detergents, etc. Synonyms: Cloxifenolum; Irgasan. CAS No. 3380-34-5. Molecular formula: C12H7Cl3O2. Mole weight: 289.5. | |
| Tridecaptin A | It is an antibiotic with antimicrobial properties produced by the strain of Bacillus polymyxa AR-110. Synonyms: D-2,4-diaminobutanoylglycyl-Dseryl-D-tryptophyl-L-seryl-L-2,4-diaminobutanoyl-D-2,4-diaminobutanoyl-L-phenylalanyl-L-r-glutamyl-L-valyl-Dalloisoleucyl. CAS No. 67922-28-5. Molecular formula: C73H115N17O20. Mole weight: 1550.79. | |
| Tridecaptin C | It is an antibiotic with antimicrobial properties produced by the strain of Bacillus polymyxa B-2. CAS No. 67922-31-0. Molecular formula: C74H117N17O21. Mole weight: 1580.82. | |
| Triiodobenzoic Acid | Used as a plant growth regulator and controller. It suppresses somatic embryo formation and postembryonic shoot/root development in eleutherococcus senticosus. Synonyms: 2,3,5-TIBA; A 20812; Floraltone; Johnkolor; NSC 2582; TIB; TIBA. Grade: ≥ 98 %. CAS No. 88-82-4. Molecular formula: C7H3I3O2. Mole weight: 499.81. | |
| Trimethoprim lactate | Trimethoprim lactate salt is used as an antibacterial agent, primarily active against most gram-negative and gram-positive aerobic bacteria. It inhibits dihydrofolate reductase. Synonyms: Trimethoprim lactic Acid. Grade: ≥98%. CAS No. 23256-42-0. Molecular formula: C17H24N4O6. Mole weight: 380.39. | |
| Triostin A | The compound of triosteomycin exhibited anti-gram-positive bacteria and mycobacteria, and had a strong inhibitory effect on Miyono adenocarcinoma, Ridgway osteosarcoma, Mecca lymphoid sarcoma and leukemia. Synonyms: N,N'-[(1R,4S,7R,11S,14R,17S,20R,24S)-11,24-Diisopropyl-2,4,12,15,17,25-hexamethyl-3,6,10,13,16,19,23,26-octaoxo-9,22-dioxa-28,29-dithia-2,5,12,15,18,25-hexaazabicyclo[12.12.4]triacontan-7,20-diyl]di(2-chinoxalincarboxamid). Grade: 99%. CAS No. 13758-27-5. Molecular formula: C50H62N12O12S2. Mole weight: 1087.23. | |
| Triostin C | Triostin C is produced by the strain of Str. triostinicus S-2-210. Triostin C exhibited anti-gram-positive bacteria and mycobacteria activity, and had a strong inhibitory effect on Miyono adenocarcinoma, Ridgway osteosarcoma, Mecca lymphoid sarcoma and leukemia. Synonyms: BRN 1071175; N-[2,4,12,15,17,25-hexamethyl-11,24-bis(3-methylbutan-2-yl)-3,6,10,13,16,19,23,26-octakis(oxidanylidene)-20-(quinoxalin-2-ylcarbonylamino)-9,22-dioxa-28,29-dithia-2,5,12,15,18,25-hexazabicyclo[12.12.4]triacontan-7-yl]quinoxaline-2-carboxamide. CAS No. 10382-35-1. Molecular formula: C54H70N12O12S2. Mole weight: 1143.33. | |
| Tripropeptin A | Tripropeptin A is a cyclic peptide antibiotic originally isolated from Lysobacter sp. BMK333-48F3. It has anti-Gram-positive bacteria activity against Staphylococcus (including MRSA), Streptococcus and Enterococcus, with MIC of 0.78-12.5μg/mL. Molecular formula: C49H79N11O19. Mole weight: 1126.21. | |
| Tripropeptin B | Tripropeptin B is a cyclic peptide antibiotic originally isolated from Lysobacter sp. BMK333-48F3. It has anti-Gram-positive bacteria activity against Staphylococcus (including MRSA), Streptococcus and Enterococcus, with MIC of 0.78-12.5μg/mL. Molecular formula: C50H81N11O19. Mole weight: 1140.24. | |
| Tripropeptin C | Tripropeptin C is a cyclic peptide antibiotic originally isolated from Lysobacter sp. BMK333-48F3. It has anti-Gram-positive bacteria activity against Staphylococcus (including MRSA), Streptococcus and Enterococcus, with MIC of 0.78-12.5μg/mL. Molecular formula: C51H83N11O19. Mole weight: 1154.26. | |
| Trisarubicinol | It is an antibiotic with anti-tumor effects originally isolated from Aclacinomycin KE303. Synonyms: 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-8-(1-hydroxyethyl)-10-((2,3,6-trideoxy-4-O-(2,6-dideoxy-4-O-((2R-trans)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-. CAS No. 80470-08-2. Molecular formula: C40H51NO15. Mole weight: 785.83. | |
| Tryprostatin B | Tryprostatin B is a natural compound isolated from Aspergillus fumigatus and arrests cell cycle progression at the G2/M phase. Synonyms: triprostatin B; (-)-Tryprostatin B; (3S,8aS)-3-{[2-(3-methylbut-2-en-1-yl)-1H-indol-3-yl]methyl}hexahydropyrrolo[1,2-a]pyrazine-1,4-dione. CAS No. 179936-52-8. Molecular formula: C21H25N3O2. Mole weight: 351.44. | |
| TS 155-2 | A macrocyclic lactone related to hygrolidin but produced by a different streptomyces species. TS155-2 is an inhibitor of calcium entry into the cell induced by thrombin stimulation. It has antihypertensive, antiplatelet, antiischemia and anti-inflammatory activities. Synonyms: Antibiotic TS 155-2; 2E-butenedioic acid-1-[(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14E)-10-hydroxy-3-methoxy-7,9,11,13,15-pentamethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-yl] ester; JBIR 100. Grade: >95% by HPLC. CAS No. 303009-07-6. Molecular formula: C39H60O11. Mole weight: 704.89. | |
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