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Sanglifehrin C
It is a cyclophilin combination produced by the strain of Streptomyces sp. A92-308110. The affinity of Sanglifehrin C to Cyclophilin is similar to Cyclosporin A. The immunosuppressive effect of Sanglifehrin is lower than Cyclosporin A by mixed lymphocyte reaction assay. Synonyms: SFC. Molecular formula: C61H93N5O13. Mole weight: 1104.41.
Sanglifehrin D
It is a cyclophilin combination produced by the strain of Streptomyces sp. A92-308110. The affinity of Sanglifehrin D to Cyclophilin is similar to Cyclosporin A. The immunosuppressive effect of Sanglifehrin is lower than Cyclosporin A by mixed lymphocyte reaction assay. Synonyms: SFD. Molecular formula: C61H91N5O12. Mole weight: 1086.40.
Sannamycin B
It is an aminoglycoside antibiotic produced by the strain of Str. sannanensis sp. nov. It has only weak antibacterial activity against a few bacteria. Synonyms: Istamycin A0; Antibiotic KA 7038III; KA 7038III; L-chiro-Inositol, 4-amino-3-O-(2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-D-erythro-hexopyranosyl)-1,4,5-trideoxy-6-O-methyl-1-(methylamino)-; 4-Amino-3-O-[2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-D-erythro-hexopyranosyl]-1,4,5-trideoxy-6-O-methyl-1-(methylamino)-L-chiro-inositol; ara-sangivamycin. CAS No. 72503-80-1. Molecular formula: C15H32N4O4. Mole weight: 332.44.
Sannamycin C
It is an aminoglycoside antibiotic produced by the strain of Str. sannanensis sp. nov. It has weak antibacterial activity against Gram-positive bacteria. Synonyms: 5-Amino-6-O-[2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-D-erythro-hexopyranosyl]-2,4,5-trideoxy-3-O-methyl-2-(methylamino)-D-epi-inositol; Antibiotic KA-7038VI; KA-7038VI; D-Epi-inositol, 5-amino-6-o-(2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-D-erythro-hexopyranosyl)-2,4,5-trideoxy-3-o-methyl-2-(methylamino)-; 3-Episannamycin B. CAS No. 73522-71-1. Molecular formula: C15H32N4O4. Mole weight: 332.44.
Sannamycin E
It is an aminoglycoside antibiotic produced by the strain of Str. sannanensis sp. nov. It has weak antibacterial activity against Gram-positive bacteria. Synonyms: Istamycin AP; 3-Amino-2,3,6-trideoxy-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-6-methylamino-D-myo-inositol; Antibiotic KA-7038II; KA-7038-II. CAS No. 73051-92-0. Molecular formula: C13H28N4O4. Mole weight: 304.39.
Sannamycin F
It is an aminoglycoside antibiotic produced by the strain of Str. sannanensis sp. nov. It has weak antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Synonyms: 5-Amino-3-O-methyl-2-(methylamino)-6-O-[2-[[(formylamino)acetyl]amino]-6-(methylamino)-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl]-2,4,5-trideoxy-D-epi-inositol; Antibiotic KA-7038VIII. CAS No. 83931-91-3. Molecular formula: C18H35N5O6. Mole weight: 417.50.
Sannamycin G
It is an aminoglycoside antibiotic produced by the strain of Str. sannanensis sp. nov. It has only weak antibacterial activity against a few bacteria. Synonyms: 2-Amino-1,2,5-trideoxy-3-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-6-O-methyl-5-(methylamino)-D-chiro-inositol; Antibiotic KA-7038V; Istamycin X0; KA-7038V; D-Chiro-inositol, 2-amino-1,2,5-trideoxy-3-o-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl)-6-o-methyl-5-(methylamino)-. CAS No. 73522-72-2. Molecular formula: C14H30N4O4. Mole weight: 318.41.
Sannamycin H
It is an aminoglycoside antibiotic produced by the strain of Str. sannanensis sp. nov. It has only weak antibacterial activity against a few bacteria. Synonyms: Istamycin Y0; 3-Amino-2,3,6-trideoxy-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-1-O-methyl-6-(methylamino)-D-myo-inositol; Antibiotic KA-7038VII; KA-7038VII; D-myo-Inositol, 3-amino-2,3,6-trideoxy-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl)-1-O-methyl-6-(methylamino)-. CAS No. 73491-61-9. Molecular formula: C14H30N4O4. Mole weight: 318.41.
Sannamycin J
It is an aminoglycoside antibiotic produced by the strain of Str. sannanensis sp. nov. It has weak antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Synonyms: 5-Amino-6-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-3-O-methyl-2-(methylamino)-2,4,5-trideoxy-D-epi-inositol; Antibiotic KA-7038IX; KA-7038IX. CAS No. 83997-42-6. Molecular formula: C14H30N4O4. Mole weight: 318.41.
Sannamycin K
It is an aminoglycoside antibiotic produced by the strain of Str. sannanensis sp. nov. It has weak antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Synonyms: 3-Amino-4-O-[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]-6-(methylamino)-2,3,6-trideoxy-D-myo-inositol; Antibiotic KA-7038X; KA-7038X; 4',5'-Didehydrosannamycin E. CAS No. 83919-30-6. Molecular formula: C13H26N4O4. Mole weight: 302.37.
Sannamycin L
It is an aminoglycoside antibiotic produced by the strain of Str. sannanensis sp. nov. It has weak antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Synonyms: 3,6-Diamino-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-2,3,6-trideoxy-D-myo-inositol; Antibiotic KA-7038XI; KA-7038XI. CAS No. 83946-32-1. Molecular formula: C12H26N4O4. Mole weight: 290.36.
Santin
Santin is a flavonoid compound found in Alnus japonica and Grindelia glutinosa. It has anti-inflammatory activity and inhibits cyclo-oxygenase and 5-lipoxygenase pathways of arachidonic metabolism. Synonyms: 2-(4-Methoxyphenyl)-5,7-dihydroxy-3,6-dimethoxy-4H-1-benzopyran-4-one; 3,4',6-Trimethoxy-5,7-dihydroxyflavone; 5,7-Dihydroxy-3,6,4'-trimethoxyflavone; 6-Hydroxykaempferol 3,4',6-trimethyl ether; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3,6-dimethoxy-2-(4-methoxyphenyl)-; Centauridin; 3-Methylbetuletol. Grade: ≥95%. CAS No. 27782-63-4. Molecular formula: C18H16O7. Mole weight: 344.32.
Sapurimycin
It is produced by the strain of Str. sp. DO-116. It has anti-gram-positive bacteria effect. In vivo, it has the effect of anti-leukemia P388 and sarcoma 180 cells. Determination in vitro, it has the effect of causing single strand breaks in superhelical plasmid DNA. Synonyms: Antibiotic DC 116; 4H-Anthra(1,2-b)pyran-5-acetic acid, 7,12-dihydro-8,11-dihydroxy-2-(2-methyl-3-(1-propenyl)oxiranyl)-4,7,12-trioxo-, (2-alpha,3-alpha(Z))-(+)-. CAS No. 133021-37-1. Molecular formula: C25H18O9. Mole weight: 462.40.
Saquayamycin A
It is produced by the strain of Str. nodosus MH190-16F3. It has antimicrobial effect, but it has weaker effect against gram-negative bacteria. It has inhibitory effect on leukemia P388 cells and adriamycin-resistant P388 cells. Synonyms: saquayamycin; Benz[a]anthracene-1,7,12(2H)-trione, 9-[2,6-dideoxy-4-O-[(2R,6S)-5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl]-b-D-arabino-hexopyranosyl]-3-[[(2S,5S,6S)-5-[[(2R,6S)-5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl]oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-, (3R,4aR,12bS)-; Benz[a]anthracene-1,7,12(2H)-trione, 9-[2,6-dideoxy-4-O-[(2R-trans)-5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl]-b-D-arabino-hexopyranosyl]-3-[[5-[(5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-,[2S-[2a(3S*,4aS*,12bR*),5b(2S*,6R*),6b]]-. CAS No. 99260-65-8. Molecular formula: C43H48O16. Mole weight: 820.83.
Saquayamycin B
It is produced by the strain of Str. nodosus MH190-16F3. It has antimicrobial effect, but it has weaker effect against gram-negative bacteria. It has inhibitory effect on leukemia P388 cells and adriamycin-resistant P388 cells. Synonyms: Benz[a]anthracene-1,7,12(2H)-trione, 9-[[2',3-anhydro]-2,6-dideoxy-4-O-(3,6-dideoxy-a-L-erythro-hexopyranos-4-ulos-1-yl)-b-D-arabino-hexopyranosyl]-3-[[(2S,5S,6S)-5-[[(2R,6S)-5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl]oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-, (3R,4aR,12bS)-; Benz[a]anthracene-1,7,12(2H)-trione, 9-[[2',3-anhydro]-2,6-dideoxy-4-O-(3,6-dideoxy-a-L-erythro-hexopyranos-4-ulos-1-yl)-b-D-arabino-hexopyranosyl]-3-[[5-[(5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-, [2S-[2a(3S*,4aS*,12bR*),5b(2S*,6R*),6b]]-. CAS No. 99260-67-0. Molecular formula: C43H48O16. Mole weight: 820.83.
Saquayamycin B1
It is produced by the strain of Str. nodosus MH190-16F3. It has antimicrobial effect, but it has weaker effect against gram-negative bacteria. It has inhibitory effect on leukemia P388 cells and adriamycin-resistant P388 cells. Synonyms: Benz[a]anthracene-1,7,12(2H)-trione, 9-[[2',3-anhydro]-2,6-dideoxy-4-O-(3,6-dideoxy-RL-erythro-hexopyranos-4-ulos-1-yl)-a-Darabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3,4a,8,12b-tetrahydroxy-3-methyl-, (3R,4aR,12bS)-. Grade: ≥95%. CAS No. 99260-68-1. Molecular formula: C31H32O12. Mole weight: 596.58.
Saquayamycin C
It is produced by the strain of Str. nodosus MH190-16F3. It has antimicrobial effect, but it has weaker effect against gram-negative bacteria. It has inhibitory effect on leukemia P388 cells and adriamycin-resistant P388 cells. Synonyms: Benz[a]anthracene-1,7,12(2H)-trione, 9-[2,6-dideoxy-4-O-[(2R,6S)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-b-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-3-[[(2S,5S,6S)-tetrahydro-6-methyl-5-[[(2R,6S)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]oxy]-2H-pyran-2-yl]oxy]-, (3R,4aR,12bS)-; Benz[a]anthracene-1,7,12(2H)-trione, 9-[2,6-dideoxy-4-O-[(2R-trans)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-b-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-3-[[tetrahydro-6-methyl-5-[(tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl)oxy]-2H-pyran-2-yl]oxy]-, [2S-[2a(3S*,4aS*,12bR*),5b(2S*,6R*),6b]]-. CAS No. 99260-70-5. Molecular formula: C43H52O16. Mole weight: 824.86.
Saquayamycin C1
It is produced by the strain of Str. nodosus MH190-16F3. It has antimicrobial effect, but it has weaker effect against gram-negative bacteria. It has inhibitory effect on leukemia P388 cells and adriamycin-resistant P388 cells. Synonyms: (3R)-9-[4-O-[(2R,6S)-Tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-2,6-dideoxy-β-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3α,4aα,8,12bα-tetrahydroxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione. CAS No. 99260-69-2. Molecular formula: C31H34O12. Mole weight: 598.59.
Saquayamycin D
It is produced by the strain of Str. nodosus MH190-16F3. It has antimicrobial effect, but it has weaker effect against gram-negative bacteria. It has inhibitory effect on leukemia P388 cells and adriamycin-resistant P388 cells. Synonyms: Benz[a]anthracene-1,7,12(2H)-trione, 9-[[2',3-anhydro]-2,6-dideoxy-4-O-(3,6-dideoxy-a-L-erythro-hexopyranos-4-ulos-1-yl)-b-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-3-[[(2S,5S,6S)-tetrahydro-6-methyl-5-[[(2R,6S)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]oxy]-2H-pyran-2-yl]oxy]-, (3R,4aR,12bS)-; Benz[a]anthracene-1,7,12(2H)-trione, 9-[[2',3-anhydro]-2,6-dideoxy-4-O-(3,6-dideoxy-a-L-erythro-hexopyranos-4-ulos-1-yl)-b-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-3-[[tetrahydro-6-methyl-5-[(tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl)oxy]-2H-pyran-2-yl]oxy]-, [2S-[2a(3S*,4aS*,12bR*),5b(2S*,6R*),6b]]-. CAS No. 99260-71-6. Molecular formula: C43H50O16. Mole weight: 822.85.
Saricandin
It is produced by the strain of Fusarium sp. AB 2202 W-161. It has weak antifungal activity. Sorbitol can offset its antifungal activity. It inhibits glucan synthase with ID50 of 242.0 μg/mL. Synonyms: -D-Galactopyranoside, (1S,3'R,4'R,5'R,6'R)-3',4',5',6'-tetrahydro-3',5,7-trihydroxy-6'-(hydroxymethyl)-4'-[[(2E,4E,8E,10E)-7-hydroxy-1-oxo-2,4,8,10-hexadecatetraenyl]oxy]-spiro[isobenzofuran-1(3H),2'-[2H]pyran]-5'-yl,6-[(2E)-3-phenyl-2-propenoate]. CAS No. 178494-90-1. Molecular formula: C44H54O16. Mole weight: 838.89.
Sarkomycin A
It is a cyclopentane derivative of antibiotic produced by the strain of Str. erythrochromogenes W-115-C. It has anti-bacterial effect, but the effect is weak. Serum and cysteine can reduce its antibacterial activity. It can inhibit HeLa cells and Eichler ascites cancer cells in vitro. Synonyms: Sarkomycin; (r)-sarkomycin; (R)-2-methylene-3-oxocyclopentanecarboxylic acid; Cyclopentanecarboxylic acid, 2-methylene-3-oxo-, (R)-; Sarcomycin. CAS No. 489-21-4. Molecular formula: C7H8O3. Mole weight: 140.14.
Sartorypyrone A
Sartorypyrone A is a meroditerpene metabolite produced by Neosartorya fungal species, displaying antibacterial and antibiofilm activities. It shows inhibitory effects against various Gram-positive bacteria. It also suppresses the growth of MCF-7 breast, NCI-H460 lung and A375-C5 melanoma cancer cell lines. Synonyms: 20-O-Acetyl Sartorypyrone D; rel-(+)-3-[(2E,6E)-9-[(1R,3S)-3-(acetyloxy)-2,2-dimethyl-6-methylenecyclohexyl]-3,7-dimethyl-2,6-nonadien-1-yl]-4-hydroxy-6-methyl-2H-pyran-2-one. Grade: ≥95%. CAS No. 1452396-10-9. Molecular formula: C28H40O5. Mole weight: 456.61.
Sarubicin B
It is produced by the strain of Str. violaceoruber sp. JA 2861. It has anti-gram-positive bacteria effect, but no anti-gram-negative bacteria, fungi and yeast effects. Synonyms: 2-Naphthalenecarboxamide, 5-acetyl-3-amino-1,4-dihydro-1,4-dioxo-. CAS No. 84745-01-7. Molecular formula: C13H10N2O4. Mole weight: 258.23.
SB-203207
SB-203207 is a tRNA synthetase inhibitor produced by Streptomyces sp. NCIMB 40513. Synonyms: SB 203207; SB203207. Molecular formula: C19H31N5O8S. Mole weight: 489.5.
SB-203208
SB-203208 is a tRNA synthetase inhibitor produced by Streptomyces sp. NCIMB 40513. Synonyms: SB 203208; SB203208. Molecular formula: C29H42N6O9S. Mole weight: 650.7.
SB-219383
SB-219383 is a tyrosyl tRNA synthetase inhibitor produced by Micromonospora sp. NCIMB 40684. Synonyms: SB 219383; SB219383. Molecular formula: C17H23N3O9. Mole weight: 413.4.
SB 22484
SB 22484 is a member of the aurodox type antibiotic group produced in submerged-fermentation cultures of Streptomyces sp. NRRL 15496. It is composed of two pairs of isomers with MW's of 752 and 766. It strongly inhibited neisseriae and were also active against Streptococci, Ureaplasma urealyticum and Haemophilus influenzae. Synonyms: SB-22484; SB22484; Antibiotic SB 22484.
SB-253514
SB-253514 is an inhibitor of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579. Synonyms: SB 253514; SB253514. Molecular formula: C28H46N2O9. Mole weight: 554.7.
SB-311009
SB-311009 is an inhibitor of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579. Synonyms: SB 311009; SB311009. Molecular formula: C22H36N2O5. Mole weight: 408.5.
SB-315021
SB-315021 is an inhibitor of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579. Synonyms: SB 315021; SB315021. Molecular formula: C28H46N2O9. Mole weight: 554.7.
SC-28762
SC-28762 is an antibiotic produced by Spicaria divaricata NRRL 5771. It has moderate activity against gram-positive, gram-negative bacteria and fungi. Synonyms: SC 28762; SC28762. CAS No. 35483-50-2. Molecular formula: C34H30O14. Mole weight: 662.6.
SC-28763
SC-28763 is an antibiotic produced by Spicaria divaricata NRRL 5771. It has activity against gram-positive, gram-negative bacteria and fungi, which is stronger than that of SC-28762. Synonyms: SC 28763; SC28763. CAS No. 55051-93-9. Molecular formula: C34H30O13. Mole weight: 646.6.
SC-30532
SC-30532 is an antibiotic produced by Spicaria divaricata NRRL 5771. It has moderate activity against Clostridium perfringens and Trichomonas vaginolis at low concentrations. Synonyms: SC 30532; SC30532. CAS No. 64596-90-3. Molecular formula: C34H30O12. Mole weight: 630.6.
Scabrosin acetate butanoate
Scabrosin acetate butanoate is an antitumor epidithiapiperazinedione isolated from the lichen Usnea. Synonyms: (1aS,2S,4aR,6aS,6bR,7aS,8S,10aR,12aS,12bR)-8-(Acetyloxy)-1a,2,6a,6b,7a,8,12a,12b-octahydro-5,11-dioxo-5H,11H-4a,10a-epidithio-4H,10H-bisoxireno[g,g']pyrazino[1,2-a:4,5-a']diindol-2-yl butanoate; Butanoic acid, (1aS,2S,4aR,6aS,6bR,7aS,8S,10aR,12aS,12bR)-8-(acetyloxy)-1a,2,6a,6b,7a,8,12a,12b-octahydro-5,11-dioxo-5H,11H-4a,10a-epidithio-4H,10H-bisoxireno[g,g']pyrazino[1,2-a:4,5-a']diindol-2-yl ester; Ambewelamide A. CAS No. 220345-71-1. Molecular formula: C24H24N2O8S2. Mole weight: 532.59.
Scensidin is a new depsidone isolated from the lichen Buellia canescens. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 2,7-dichloro-3,8-dimethoxy-1,6-dimethyl-; 2,8-dichloro-3,9-dimethoxy-1,7-dimethylbenzo[b][1,4]benzodioxepin-6-one. CAS No. 86190-23-0. Molecular formula: C17H14Cl2O5. Mole weight: 369.20.
Sch-20561
Sch-20561 is a cyclic dehydropeptide lactone produced by Aeromonas sp. W-10 NRRL B11053. It is a major component of W-10 antifungal antibiotic. Synonyms: Sch 20561. Molecular formula: C57H86N12O16. Mole weight: 1195.4.
Sch-20562
Sch-20562 is a cyclic dehydropeptide lactone produced by Aeromonas sp. W-10 NRRL B11053. It is a major component of W-10 antifungal antibiotic. Synonyms: Sch 20562. Molecular formula: C63H96N12O21. Mole weight: 1357.5.
Sch 218157
Sch 218157 is a cyclodepsipeptide isolated from an unidentified fungus MYCO-2833. It selectively binds to NK2 receptor with IC50 of 68 nmol/L. Synonyms: Sch-218157. Molecular formula: C57H89N11O13. Mole weight: 1136.4.
Sch-31828
Sch-31828 is a novel antibiotic from a Microbispora sp. SCC 1438. It is commonly used as methyl ether form. Synonyms: Sch 31828; Antibiotic EV22; EV 22. CAS No. 115216-83-6. Molecular formula: C17H18O6. Mole weight: 318.32.
Sch-38516
Sch-38516 is a macrolactam antibiotic produced by Actinomadura sp. SCC 1776 and SCC 1777. It exhibits activity against Candida sp. with MIC of 0.91 μg/mL. Synonyms: Sch 38516. CAS No. 128563-23-5. Molecular formula: C24H46N2O5. Mole weight: 442.6.
Sch-38518
Sch-38518 is a macrolactam antibiotic produced by Actinomadura sp. SCC 1776 and SCC 1777. It exhibits activity against Candida sp. with MIC of 1.81 μg/mL. Synonyms: Sch 38518. CAS No. 135559-94-3. Molecular formula: C25H48N2O5. Mole weight: 456.7.
Sch-39185
Sch-39185 is a macrolactam antibiotic produced by Actinomadura sp. SCC 1776 and SCC 1777. It exhibits activity against Candida sp. with MIC of 2 μg/mL. Synonyms: Sch 39185. CAS No. 135559-95-4. Molecular formula: C25H48N2O5. Mole weight: 456.7.
Sch 40832
Sch 40832 is an antibiotic produced by Micromonospora carbonacea var africana. It exhibits activity against gram-positive bacteria with MIC of 0.1-1.0 μg/mL. Synonyms: Antibiotic Sch 40832; Sch-40832. Molecular formula: C84H104N18O26S5. Mole weight: 1942.2.
Sch 420789
Sch 420789 is a phospholipase D inhibitor produced by an unidentified fungus SCF 0953. Synonyms: Sch-420789. Molecular formula: C27H36O6. Mole weight: 456.6.
Sch 42137
Sch 42137 is an antifungal antibiotic isolated from Actinoplanes sp. It exhibited MIC values less than 0.125 μg/mL against yeasts and dermatophytes. Synonyms: Antibiotic Sch 42137; Sch-42137. CAS No. 142383-44-6. Molecular formula: C29H27NO10. Mole weight: 549.5.
Sch 466457
Sch 466457 is a peptide active against Candida, dermatophytes and Aspergillus with MIC of 8.9, 20 and 16 microg/mL. Synonyms: Sch-466457. Molecular formula: C80H140N20O20. Mole weight: 1702.08.
Sch 47554
Sch 47554 is an antifungal antibiotic produced from Streptomyces sp. SCC-2135. Synonyms: Antibiotic Sch 47554; Sch-47554. CAS No. 150050-20-7. Molecular formula: C37H38O13. Mole weight: 690.7.
Sch 47555
Sch 47555 is an antifungal antibiotic produced from Streptomyces sp. SCC-2135. Synonyms: Antibiotic Sch 47555; Sch-47555. CAS No. 150050-21-8. Molecular formula: C37H42O13. Mole weight: 694.7.
Sch 484129
Sch 484129 is a glycolipid antibiotic isolated from the fermentation broth of Basidiomycete HAM-240. It displayed antifungal activity against Saccharomyces and Aspergillus strains. Synonyms: Sch-484129. Molecular formula: C31H54O12. Mole weight: 618.8.
Sch 484130
Sch 484130 is a glycolipid antibiotic isolated from the fermentation broth of Basidiomycete HAM-240. It displayed antifungal activity against Saccharomyces and Aspergillus strains. Synonyms: Sch-484130. Molecular formula: C31H54O12. Mole weight: 618.8.
Sch 50673
Sch 50673 is an antitumor metabolite produced by Nattrassia mangiferae. Synonyms: Sch-50673. Molecular formula: C21H14O8. Mole weight: 394.3.
Sch 50676
Sch 50676 is an antitumor metabolite produced by Nattrassia mangiferae. Synonyms: Sch-50676. Molecular formula: C20H14O5. Mole weight: 334.3.
Sch 528647
Sch 528647 is an antitumor antibiotic produced by Aspergillus fumigatus. Synonyms: Sch-528647. Molecular formula: C26H34O6. Mole weight: 442.5.
Sch 52900
Sch 52900 is an inhibitor of c-fos proto-oncogene induction, which is isolated from the fermentation of broth of the fungal culture (SCF-1168), Gliocladium sp. Synonyms: Sch-52900. Molecular formula: C31H30N6O7S4. Mole weight: 726.9.
Sch 52901
Sch 52901 is an inhibitor of c-fos proto-oncogene induction, which is isolated from the fermentation of broth of the fungal culture (SCF-1168), Gliocladium sp. Synonyms: Sch-52901. Molecular formula: C31H30N6O6S4. Mole weight: 710.9.
Sch 56396
Sch 56396 is a c-fos proto-oncogene inhibitor produced by the fungus Tolypocladium sp. Synonyms: Sch-56396. Molecular formula: C17H20N2O3S. Mole weight: 332.4.
Sch 57404
Sch 57404 is an antifungal antibiotic produced by an unidentified fungus SCF1082A. Synonyms: Sch-57404. Molecular formula: C27H36O9. Mole weight: 504.6.
Sch 575867
Sch 575867 is an antifungal antibiotic isolated from a deep-water marine sponge Astroscleridae. It is effective against brewer's yeast with MIC of 15 μg/mL. Synonyms: Sch-575867. Molecular formula: C32H51Na3O13S3. Mole weight: 808.9.
Sch 599473
Sch 599473 is a sesterterpene isolated from from a marine sponge, Ircinia sp. It inhibits CCR7 receptor with IC50 of 33 μg/mL. Synonyms: Sch-599473. Molecular formula: C25H40O5S. Mole weight: 452.6.
Sch 725674
It is a macrocyclic lactone structurally related to gloeosporone. It is a self-germination inhibitor produced by colletotrichum gloeosporioides. It exhibits moderate antifungal activity. Synonyms: Antibiotic Sch 725674; (3E,5R,6S,8R,14R)-5,6,8-Trihydroxy-14-pentyloxacyclotetradec-3-en-2-one; Sch-725674; 5R,6S,8R-trihydroxy-14R-pentyl-oxacyclotetradec-3E-en-2-one. Grade: >95% by HPLC. CAS No. 877061-66-0. Molecular formula: C18H32O5. Mole weight: 328.44.
It is a squalene synthase inhibitor produced by the strain of Schizophyllum commune SANK 17785. It inhibits squalene synthase with IC50 of 0.84 μmol/L. 1000 μg/mL of Schizostatin has no antibacterial effect on the tested bacteria, mycobacteria, yeast and mycoplasma. Synonyms: schizostatin E; 2-Butenedioic acid, 2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-, (2E)-; 2-Butenedioic acid, 2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-, (E,E,E)-. CAS No. 163564-55-4. Molecular formula: C20H30O4. Mole weight: 334.45.
Sclerotigenin
Sclerotigenin is a natural benzodiazepine originally isolated from Penicillium sclerotigenum that acts as an insect growth regulator and has an anti-insectan activity against the caterpillar, Helicoverpa zea. Synonyms: 6,7-dihydro-5H,13H-quinazolino[3,2-a][1,4]benzodiazepine-5,13-dione; (±)-Sclerotigenin; 6,7-dihydro-6,8,13a-triaza-benzo[3,4]cyclohepta[1,2-b]naphthalene-5,13-dione; 6,7-dihydrobenzo[6,7][1,4]diazepino[2,1-b]quinazoline-5,13-dione. Grade: ≥95%. CAS No. 65641-84-1. Molecular formula: C16H11N3O2. Mole weight: 277.28.
Sclerotioramine
Sclerotioramine has strong antifouling activity. Synonyms: (+)Sclerotiolamine; 6,8(2H,7H)-Isoquinolinedione, 7-(acetyloxy)-5-chloro-3-(3,5-dimethyl-1,3-heptadienyl)-7-methyl- (9CI). Grade: >95% by HPLC. CAS No. 34695-81-3. Molecular formula: C21H24ClNO4. Mole weight: 389.87.
Sclerotiorin
Sclerotiorin is a metabolite isolated from Penicillium species. It inhibits soybean lipoxygenase-1 (LOX-1) with IC50 value of 4.2 μM. It also exhibits antioxidant property by scavenging free radical with an ED50 of 0.12 μM. Synonyms: [(7R)-5-chloro-3-[(1E,3E,5S)-3,5-dimethylhepta-1,3-dienyl]-7-methyl-6,8-dioxoisochromen-7-yl] acetate. Grade: ≥98%. CAS No. 549-23-5. Molecular formula: C21H23ClO5. Mole weight: 390.86.
Scorodonin
It is produced by the strain of Marasmius scorodonius. It has anti-bacterial, Streptomyces and fungal effects. In vitro it inhibits DNA-dependent RNA polymerases with IC50 of 25 μg/mL. Synonyms: (R)-7-Chloro-2,3-heptadien-5-yn-1-ol; 2,3-Heptadien-5-yn-1-ol, 7-chloro-, (R)-. CAS No. 74660-77-8. Molecular formula: C7H7ClO. Mole weight: 142.58.
Scyphostatin
It is a mammalian N-SMase inhibitor produced by the strain of Trichopeziza mollissima SANK 13892. It inhibits N-SMase with IC50 of 1.0 μmol/L. Synonyms: (2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl-hexadeca-2,4,6,12-tetraenoic acid [(S)-1-hydroxymethyl-2-((1S,2S,6S)-2-hydroxy-3-oxo-7-oxa-bicyclo[4.1.0]hept-4-en-2-yl)-ethyl]-amide; (2'S,2''E,4S,4''E,5S,6S,6''E,8''R,10''S,12''E,14''R)-4,5-epoxy-6-hydroxy-6-[3'-hydroxy-2'-(8'',10'',12'',14''-tetramethylhexadeca-2'',4'',6'',12''-tetraenoylamino)-propyl]-2-cyclohexen-1-one; (+)-scyphostatin. CAS No. 169062-93-5. Molecular formula: C29H43NO5. Mole weight: 485.66.
Scytalidin
It is a terpenoid antibiotic produced by the strain of Scytalidium sp. FSC-470. It has antifungal effect. The antibacterial activity is strongest when the pH value of liquid determination is 3.5, and the activity decreases when the pH value increases. Synonyms: Scytalidic-acid; NSC-236264; 1H-Cyclonona(1,2-c:5,6-c')difuran-1,3,6,8(4H)-tetrone, 10-butyl-5,9,10,11-tetrahydro-10-hydroxy-4-pentyl-, (4S,10R)-; 1H-Cyclonona[1,2-c:5,6-c']difuran-1,3,6,8(4H)-tetrone, 10-butyl-5,9,10,11-tetrahydro-10-hydroxy-4-pentyl-, [4S-(4R*,10S*)]-. CAS No. 39012-16-3. Molecular formula: C22H28O7. Mole weight: 404.45.
Scytalol A
It is produced by the strain of Scytalidium sp. 36-93. It selectively inhibits biosynthesis of dihydroxynaphthalene melanin in Lachnellula sp. A32-89, but does not inhibit the growth of the strain. Synonyms: 10H-Naphtho[2,3-c]pyran-10-one,1,3,4,4a,5,10a-hexahydro-3,5,9-trihydroxy-7-methoxy-3-methyl-, (3R,4aS,5S,10aR)-rel-(+)-. CAS No. 208183-19-1. Molecular formula: C15H18O6. Mole weight: 294.30.