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dCTP - lyophilized
The lyophilized form of dCTP. dCTP is a nucleoside triphosphate used in DNA synthesis by being incorporated into DNA strand. Synonyms: 2'-Deoxycytidine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C9H13N3Na3O13P3* 3H2O. Mole weight: 587.14.
dCTP solution - Lithium Salt
The lithium salt solution form of dCTP. dCTP is a nucleoside triphosphate used in DNA synthesis by being incorporated into DNA strand. Grades: ≥ 99% by HPLC. Molecular formula: C9H16N3O13P3 (free acid). Mole weight: 467.15 (free acid).
dCTP solution - Sodium Salt
The sodium salt solution form of dCTP. dCTP is a nucleoside triphosphate used in DNA synthesis by being incorporated into DNA strand. Grades: ≥ 99% by HPLC. Molecular formula: C9H16N3O13P3 (free acid). Mole weight: 467.15 (free acid).
ddATP-α-S
ddATP-α-S is used in mass spectrometric genotyping. Synonyms: 2', 3'- Dideoxyadenosine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers. Grades: ≥ 95% by HPLC for mixture of Rp-/Sp-isomers. CAS No. 154902-26-8. Molecular formula: C10H16N5O10P3S (free acid). Mole weight: 491.3 (free acid).
ddCTP
ddCTP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddCTP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dCTP in cells. Uses: Ddctp is an inhibitor of reverse transcriptases from retroviruses. Synonyms: 2',3'-Dideoxycytidine-5'-Triphosphate; Zalcitabine triphosphate; Cytidine 5'-(tetrahydrogen triphosphate), 2',3'-dideoxy-. Grades: ≥95% by AX-HPLC. CAS No. 66004-77-1. Molecular formula: C9H16N3O12P3 (free acid). Mole weight: 451.16 (free acid).
ddCTP-α-S
ddCTP-α-S is used in mass spectrometry genotyping. Synonyms: 2', 3'- Dideoxycytidine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers. Grades: ≥ 95% by HPLC for mixture of Rp-/Sp-isomers. CAS No. 154771-49-0. Molecular formula: C9H16N3O11P3S (free acid). Mole weight: 467.2 (free acid).
D-Desthiobiotin-7-dATP
D-Desthiobiotin-7-dATP is a vital component in biomedical research, widely used for DNA labeling and sequencing applications. It serves as a high-affinity substrate for certain DNA polymerases and DNA-modifying enzymes. This product aids in the study of DNA-protein interactions. Synonyms: N6-(6-Amino)hexyl-dATP - D-Desthiobiotin; N6-(6-Amino)hexyl-2'-deoxyadenosine-5'-triphosphate - D-Desthiobiotin, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C26H45N8O14P3. Mole weight: 786.6.
ddGTP-α-S
ddGTP-α-S is used in mass spectrometric genotyping. Synonyms: 2', 3'- Dideoxyguanosine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers. Grades: ≥ 95% by HPLC for mixture of Rp-/Sp-isomers. CAS No. 154771-50-3. Molecular formula: C10H16N5O11P3S (free acid). Mole weight: 507.3 (free acid).
ddNTP bundle
ddNTP bundle is a mixture of ddATP, ddTTP, ddGTP and ddCTP. ddNTP is an inhibitor of DNA polymerase used to terminate chain extension. Uses: Ddntp is an inhibitor of dna polymerase. Synonyms: 2',3'-Dideoxyadenosine-5'-triphosphate, Lithium salt; 2',3'-Dideoxycytidine-5'-triphosphate, Lithium salt; 2',3'-Dideoxyguanosine-5'-triphosphate, Lithium salt; 2',3'-Dideoxythymidine-5'-triphosphate, Lithium salt. Grades: ≥ 98% by HPLC, functionally tested by chain termination sequencing reactions. Molecular formula: ddATP: C10H16N5O11P3 (free acid); ddCTP: C9H16N3O12P3 (free acid); ddGTP: C10H16N5O12P3 (free acid); ddTTP: C10H17N2O13P3 (free acid). Mole weight: ddATP: 475.18 (free acid); ddCTP: 451.16 (free acid); ddGTP: 491.18 (free acid); ddTTP: 466.17 (free acid).
ddTTP
ddTTP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddTTP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dTTP in cells. Uses: Ddttp is an inhibitor of reverse transcriptases from retroviruse. Synonyms: 2',3'-Dideoxythymidine-5'-Triphosphate. Grades: ≥95% by AX-HPLC. CAS No. 611-60-9. Molecular formula: C10H17N2O13P3 (free acid). Mole weight: 466.17 (free acid).
ddUDP
ddUDP is a cutting-edge compound, proudly flaunting its title as a modified nucleotide analog. This exceptional creation acts as a premier substrate for none other than DNA polymerases. Synonyms: 2',3'-Dideoxyuridine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C9H14N2O10P2 (free acid). Mole weight: 372.16 (free acid).
ddUTP
ddUTP, a nucleotide analogue widely employed as a substrate in various molecular biology techniques such as PCR and sequencing, serves as a quintessential tool in studies pertaining to viral replication, cancer research, and drug development for diseases like AIDS. Its incorporation into DNA yields chain termination and evinces promising results in investigating DNA replication and repair mechanisms. Synonyms: ddUTP; dideoxyuridine-triphosphate. Grades: ≥90% by AX-HPLC. CAS No. 84445-38-5. Molecular formula: C9H15N2O13P3 (free acid). Mole weight: 452.14 (free acid).
ddUTP-α-S
ddUTP-α-S is used in mass spectrometric genotyping. Synonyms: 2', 3'- Dideoxyuridine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers (Rp-/Sp-ddUTP-α-S). Grades: ≥ 95% by HPLC for mixture of Rp-/Sp-isomers. CAS No. 1053668-88-4. Molecular formula: C9H15N2O12P3S (free acid). Mole weight: 468.2 (free acid).
DEAC-dUTP
DEAC-dUTP is a remarkable nucleotide, finding application in the field of molecular biology studies. It contributes indispensably to endeavors encompassing DNA sequencing, PCR techniques and DNA labeling. Synonyms: Aminoallyl-dUTP - DEAC; Diethylaminocoumarin-5-dUTP; Diethylaminocoumarin-5-aminoallyl-2'-deoxyuridine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C26H33N4O17P3 (free acid). Mole weight: 766.48 (free acid).
Decitabine Related Compound B
4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one is a derivative of β-Decitabine which is used as cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines. Synonyms: 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one; β-Decitabine-3',5'-bis(4-chlorobenzoate). Grades: > 95%. CAS No. 1034301-08-0. Molecular formula: C22H18Cl2N4O6. Mole weight: 505.31.
Deoxy Chlorocytarabine
Deoxy Chlorocytarabine is a lipophilic DNA synthesis inhibitor and has antileukemic activity. Synonyms: 2'-Chloro-2'-deoxy-1-β-D-arabinofuranosylcytosine; 5'-Chloro-5'-deoxyarabinosylcytosine; 5'-Chloroarabinosylcytosine; NSC 318799; 4-Amino-1-(5-chloro-5-deoxy-β-D-arabinofuranosyl)pyrimidin-2(1H)-one; 4-Amino-1-((2R,3S,4S,5S)-5-(chloromethyl)-3,4-dihydroxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one. CAS No. 32659-31-7. Molecular formula: C9H12ClN3O4. Mole weight: 261.66.
Deoxyribonucleic acid sodium salt
Cas No. 9007-49-2.
Descyclopropyl Abacavir
Abacavir Intermediate. Synonyms: Abacavir Related Compound A; (1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)-2-cyclopentene-1-methanol; USP Abacavir Related Compound A. Grades: > 95%. CAS No. 124752-25-6. Molecular formula: C11H14N6O. Mole weight: 246.27.
Desthiobiotin-6-Aminoallyl-2'-deoxycytidine-5'-Triphosphate is a highly specialized reagent in biomedicine used to introduce Desthiobiotin and aminoallyl groups to DNA. It is an essential tool for researchers conducting DNA labeling, detection, and purification assays. This product allows for the labeling of specific DNA sequences for downstream applications including genomic analysis, protein characterization, and DNA-protein interaction studies. Synonyms: Desthiobiotin-6-dCTP; Desthiobiotin-dCTP. Grades: ≥95% by AX-HPLC. Molecular formula: C22H37N6O15P3. Mole weight: 718.40.
Desulpho-CoA
Desulpho-CoA is an essential coenzyme that plays a crucial role in biosynthetic processes involved in the metabolism of sulfur-containing compounds. It acts as a co-substrate in various enzymatic reactions, including the degradation of cysteine and methionine. Desulpho-CoA is particularly valuable in compound for studying and developing researchs related to diseases associated with impaired sulfur metabolism, such as cystathioninuria and homocystinuria. Synonyms: Desulpho-Coenzym A, Sodium salt; Desulfocoenzyme A, Dethiocoenzyme A. Grades: ≥ 95% by HPLC. Molecular formula: C21H36N7O16P3 (free acid). Mole weight: 735.47 (free acid).
D-Fructose 1-phosphate disodium salt
D-Fructose 1-phosphate disodium salt is a crucial component used in the biomedical industry playing a vital role in the research of metabolic disorders and genetic diseases associated with defects in fructose metabolism. This product acts as a substrate for the enzymatic reaction leading to the conversion of fructose-1-phosphate to fructose-6-phosphate, facilitating normal fructose metabolism. Synonyms: D-Fructofuranose, 1-(dihydrogen phosphate), disodium salt. Grades: 90%. CAS No. 71662-09-4. Molecular formula: C6H11Na2O9P. Mole weight: 304.10.
dGDPαS
dGDPαS, a guanine nucleotide analog, is a petite molecule immensely employed in exploring GTPases, critical proteins playing crucial roles in several cellular paths. It has a remarkable utility in investigating drug mechanisms targeted at GTPases and studying illnesses like cancer, inflammatory diseases, and neurodegenerative disorders. Its varied applications in the biomedical industry have elevated its popularity and importance. Synonyms: 2'-Deoxyguanosine-5'-(α-thio)-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H15N5O9P2S (free acid). Mole weight: 443.26 (free acid).
dGpCpp
dGpCpp, a pyrophosphate analog employed in biomedical research for studying RNA and DNA polymerase activity, possesses anti-proliferative action against cancerous cells and showcases potential benefits in certain viral infections. Notably, the compound serves as an inhibitor of protein synthesis through the stimulation of mRNA degradation and the targeting of elongation factors. Synonyms: (dGMPCPP); 2'-Deoxyguanosine-5'-[(α,β)-methyleno]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 941569-34-2. Molecular formula: C11H18N5O12P3 (free acid). Mole weight: 505.21 (free acid).
dGpNHpp
dGpNHpp, a minuscule molecule, is capable of disrupting protein-protein interactions with a specific focus on the nucleotide binding domain (NBD) of CFTR, a protein afflicted with mutation in cystic fibrosis. Its viability as a therapeutic agent lies in its probable ability to rectify the rogue folding and movement patterns of the mutated CFTR protein while opening up new dimensions unconquered until now. Synonyms: (dGMPNPP); 2'-Deoxyguanosine-5'-[(α,β)-imido]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 756797-73-6. Molecular formula: C10H17N6O12P3 (free acid). Mole weight: 506.19 (free acid).
dGppNHp
dGppNHp is a modified nucleotide widely employed in studying intricate protein kinase signaling pathways. Serving as a non-hydrolyzable analog of GTP, this indispensable biochemical entity assumes a pivotal role in experimental investigations, particularly those concerning GTPases. Synonyms: (dGMPPNP); 2'-Deoxyguanosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grades: ≥ 90% by HPLC. Molecular formula: C10H17N6O12P3 (free acid). Mole weight: 506.20 (free acid).
dGTP
The lyophilized form of dGTP. dGTP is a nucleoside triphosphate used in the synthesis of DNA. Synonyms: Deoxyguanosine Triphosphate; Deoxy-GTP; Deoxyguanosine 5'-Triphosphate; 2'-Deoxyguanosine 5'-Triphosphate; 5'-DGTP; 2'-deoxy-guanosine 5'-(tetrahydrogen triphosphate); Guanosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-. Grades: ≥95% by HPLC. CAS No. 2564-35-4. Molecular formula: C10H16N5O13P3. Mole weight: 507.18.
dGTPαS
dGTPαS, a nucleotide analog, is commonly employed in enzymatic assays that investigate the mechanisms of G-protein catalyzed nucleotide exchange reactions. In addition to this, it finds widespread application as a substrate for DNA polymerase and sequencing techniques, including PCR. Its multifaceted nature makes it an essential component of numerous research studies. Synonyms: 2'-Deoxyguanosine-5'-(α-thio)-triphosphate, Sodium salt (1 : 1 Mixture of Rp and Sp isomers). Grades: ≥ 95% by HPLC. CAS No. 82337-56-2. Molecular formula: C10H16N5O12P3S (free acid). Mole weight: 523.24 (free acid).
dGTP solution - Lithium Salt
The lithium salt solution form of dGTP. dGTP is a nucleoside triphosphate used in the synthesis of DNA. Grades: ≥ 99% by HPLC. Molecular formula: C10H16N5O13P3 (free acid). Mole weight: 507.18 (free acid).
dGTP solution - Sodium Salt
The sodium salt solution form of dGTP. dGTP is a nucleoside triphosphate used in the synthesis of DNA. Grades: ≥ 99% by HPLC. Molecular formula: C10H16N5O13P3 (free acid). Mole weight: 507.18 (free acid).
Dibutyryladenosine cyclic 3',5'-monophosphate
Bucladesine is a 3',5'-cyclic purine nucleotide that is the 2'-butanoate ester and 6-N-butanoyl derivative of 3',5'-cyclic AMP. It has a role as an agonist, a vasodilator agent and a cardiotonic drug. It is a butyrate ester, a 3',5'-cyclic purine nucleotide and a member of butanamides. It derives from a 3',5'-cyclic AMP. Synonyms: Bucladesine; Dibutyryl 3',5'-cyclic AMP; Bt2 cyclic AMP; 3',5'-Cyclic AMP dibutyrate; n-6,o-2'-dibutyryl adenosine cyclic 3':5'-monophosphate; Cyclic AMP dibutyrate; N6,2'-O-dibutyryl-cAMP; [(4aR,6R,7R,7aR)-6-[6-(butanoylamino)purin-9-yl]-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d]; Bucladesine, Disodium Salt; Bucladesine, Monosodium Salt; Bucladesine, Sodium Salt. Grades: 99%. CAS No. 362-74-3. Molecular formula: C18H24N5O8P. Mole weight: 469.39.
Didanosine (DDI)
Didanosine is a reverse transcriptase inhibitor with an IC50 of 0.49 μM. Uses: Anti-hiv agents; antimetabolites; reverse transcriptase inhibitors. Synonyms: 2',3'-Dideoxyinosine; NSC 612049; DDI; BMY 40900; Dideoxyinosine; Videx; 9-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one. Grades: ≥95%. CAS No. 69655-05-6. Molecular formula: C10H12N4O3. Mole weight: 236.23.
DIG-11-ddUTP
DIG-11-ddUTP is a novel deoxyuridine triphosphate (dUTP) derivative, serving as a prodigious tool in biomedical exploration for DNA labeling. Widely applicable in cutting-edge methodologies including fluorescence in situ hybridization (FISH) and Southern blotting, this sophisticated compound enables precise detection of specialized DNA sequences and gene expression patterns. Synonyms: Digoxigenin-3-O-methylcarbonyl-ε-aminocaproyl-[5-(3-aminopropargyl) -2',3'-dideoxyuridine-5'-triphosphate], Triethylammoniumsalt. Grades: ≥ 95% by HPLC. Molecular formula: C43H63N4O20P3 (free acid). Mole weight: 1048.90 (free acid).
DIG-11-dUTP
DIG-11-dUTP is an esteemed nucleotide analogue, adroitly employed for the purpose of DNA and RNA labeling. Employing this avant-garde compound alongside sophisticated methodologies including in situ hybridization and polymerase chain reaction (PCR) decidedly furnishes the remarkable ability to scrutinize distinctive nucleic acid sequences. Synonyms: Digoxigenin-X-5-aminoallyl-2'-deoxyuridine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C43H65N4O21P3 (free acid). Mole weight: 1066.91 (free acid).
DIG-11-UTP
DIG-11-UTP is a modified nucleotide used in biomedical research for the incorporation of digoxigenin (DIG) labels into RNA molecules during transcription. This versatile product allows specific detection and localization of RNA in various applications, including in situ hybridization, Northern blotting and RT-PCR analysis. Synonyms: Digoxigenin-X-5-aminoallyl-uridine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C43H65N4O22P3 (free acid). Mole weight: 1082.92 (free acid).
Digoxigenin-11-UTP
Digoxigenin-11-UTP has been used to label RNA probes. Synonyms: Digoxigenin-X-5-aminoallyl-uridine-5'-triphosphate; Dig-11-utp. Molecular formula: C43H65N4O22P3. Mole weight: 1082.92.
Dihydrozeatin riboside
Introducing Dihydrozeatin riboside is a profoundly efficacious compound functioning as a cytokinin. It exhibits remarkable anti-inflammatory attributes. Remarkably, this product has showcased auspicious outcomes in studying inflammatory states encompassing rheumatoid arthritand Crohn's disease. Its inhibitory efficacy resides in its immunomodulatory prowess, orchestrating immune responses. Synonyms: 6-(4-hydroxy-3-methylbutylamino)-9-b-D-ribofuranosylpurine. Grades: ≥ 98% (TLC). CAS No. 22663-55-4. Molecular formula: C15H23N5O5. Mole weight: 353.37.
Di-MANT-c-diAMP
Di-MANT-c-diAMP is a fluorescent analogue of c-diAMP, the bacterial second messenger. The MANT fluorophore (λexc355 nm; λem448 nm) is sensitive for its environment and can change its spectral properties while binding. Synonyms: 2'-,2''-O-(Di-N'-methylanthraniloyl)-cyclic diadenosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C36H38N12O14P2 (free acid). Mole weight: 924.7 (free acid).
Di-MANT-c-diGMP
Di-MANT-c-diGMP is a fluorescent analogue of c-diGMP, the bacterial second messenger. The MANT fluorophore (λexc355 nm; λem448 nm) is sensitive for its environment and can change its spectral properties while binding. Synonyms: 2'-,2''-O-(Di-N'-methylanthraniloyl)-cyclic diguanosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C36H38N12O16P2 (free acid). Mole weight: 956.7 (free acid).
Diphenhydramine 3,4,5-Triacetoxy-N-β-D-glucuronide-6-methyl Ester Bromide is an intermediate used for Diphenhydramine N-β-D-Glucuronide synthesis, which is a glucuronide metabolite of Diphenhydramine in humans. Molecular formula: C30H38BrNO10. Mole weight: 652.53.
dITP solution - Sodium Salt
The sodium salt solution form of dITP. dITP is a deoxyribonucleotide that can be incorporated into DNA by polymerases. dITP exist in all cells but the concentration is very low. dITP is potentially mutagenic, and the levels of these nucleotides are controlled by ITPase. Grades: ≥ 99% by HPLC. Molecular formula: C10H15N4O13P3 (free acid). Mole weight: 492.16 (free acid).
dKTP
dKTP is a triphosphate analogue with artificial base for directed mutagenesis experiments. Grades: ≥ 95% by HPLC. CAS No. 189278-08-8. Molecular formula: C11H19N6O13P3 (free acid). Mole weight: 536.2 (free acid).
DL-10-Camphorsulfonyl Chloride
DL-10-Camphorsulfonyl Chloride, a compound found in organic synthesis reactions, is a vital component in the creation of both pharmaceuticals and agrochemicals. As a starting material for derivative synthesis, the compound shows potential in numerous biomedical applications. Synonyms: UpU RNA Dinucleotide (5'-3'); Uridine monophosphate-uridine. Grades: ≥95% by AX-HPLC. CAS No. 2415-43-2. Molecular formula: C10H15ClO3S. Mole weight: 250.7423.
DMACM-caged 8-Br-cAMP
DMACM-caged 8-Br-cAMP is a fluorescent and caged precursor of 8-bromo cyclic AMP. 8-Br-cAMP and a fluorescent coumarin analogue are released by irradiation. Synonyms: (7- Dimethylaminocoumarin- 4- yl)methyl- 8- bromoadenosine- 3', 5'- monophosphate. Grades: ≥ 98% by HPLC. Molecular formula: C22H22BrN6O8P. Mole weight: 627.4.
DMACM-caged 8-Br-cGMP
DMACM-caged 8-Br-cGMP is a fluorescent precursor of 8-bromo cyclic cGMP. 8-Br-cGMP and a fluorescent coumarin analogue are released by irradiation. It is much more lipophilic and membrane-permeant. Synonyms: (7- Dimethylaminocoumarin- 4- yl)methyl- 8- bromoguanosine- 3', 5'- monophosphate. Grades: ≥ 98% by HPLC. Molecular formula: C22H22BrN6O9P. Mole weight: 634.3.
DMB-caged-ATP
DMB-caged-ATP is a caged ATP compound, which can be photochemically uncaged to release adenosine triphosphate upon light exposure. This enables precise temporal control over ATP release in studying ATP-dependent processes and cellular signaling pathways related to various diseases, including cancer and neurodegenerative disorders. Synonyms: Adenosine-5'-triphosphate, P3 -(1-(3',5'-dimethoxyphenyl)-2-oxo-2-phenyl-ethyl)-ester, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 159899-51-1. Molecular formula: C26H30N5O16P3(free acid). Mole weight: 761.46 (free acid).
DMNPE-caged ATP diammonium salt
DMNPE-caged ATP is a nucleotide analogue of ATP which esterified with a blocking group. It blocks ATP-sensitive K channels in cardiac muscle. Synonyms: Adenosine 5'-triphosphate P"-[1-(4,5-dimethoxy-2-nitrophenyl)ethyl] ester diammonium salt. Grades: ≥98% by HPLC. Molecular formula: C20H27N6O17P3.2NH3. Mole weight: 750.44.
DMT-2'Fluoro-dA(bz) Phosphoramidite
DMT-2'Fluoro-dA(bz) Phosphoramidite is an indispensable phosphoramidite derivative compound, used extensively in the synthesis of biomedical modified oligonucleotides. It emerges as a prominent tool aimed at studying multifarious afflictions, encompassing cancer, hereditary anomalies and insidious viral invasions. Synonyms: 2'-F-Bz-A-CEP. Molecular formula: C46H51FN7O7P. Mole weight: 863.91.
DMTr-dH2U-amidite
DMTr-dH2U-amidite is an invaluable entity, emerging prominently due to its indispensability in the synthesis of nucleotide analogs and customized oligonucleotides. It assumes a pivotal function in the advancement of pharmaceuticals designed to study an array of ailments, ranging from cancer to viral infections and genetic anomalies. Synonyms: 2-Deoxy-2'-deoxy-5'-(4,4'-dimethoxytrityl)uridine-3'-CED phosphoramidite; 4(1H)-Pyrimidinone, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-. Grades: ≥95%. CAS No. 151503-28-5. Molecular formula: C39H47N4O7P. Mole weight: 714.79.
DMTr-FNA-C(Bz)phosphoramidite
DMTr-FNA-C(Bz)phosphoramidite is an essential compound assuming the role of a phosphoramidite foundational component, expediting the fabrication of nucleic acid analogs. Through its distinctive configuration, it is harnessed in the fabrication of modified oligonucleotides, specifically tailored for investigative applications, notably in the precise targeting of disease-correlated DNA or RNA sequences encompassing afflictions like cancer and viral infections. Synonyms: N4-Benzoyl-1-[[2-O- (4, 4'-dimethoxytrityloxy) -1- (hydroxymethyl) ethoxy]methyl]cytosine CED phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-[[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]methoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl ester. Grades: ≥95%. CAS No. 326802-62-4. Molecular formula: C45H52N5O8P. Mole weight: 821.90.
dNaM
dNaM is a synthetic biology tool used in genetic research for nucleotide modification. It allows for the creation of synthetic sequence-specific DNA-binding proteins for gene regulation and therapy. It has potential applications in treating genetic disorders and diseases like cancer through targeted gene editing. Grades: ≥ 97%. CAS No. 1117893-19-2. Molecular formula: C16H18O7. Mole weight: 274.31.
DNP-TEG CEP
DNP-TEG CEP is a prominent biomedical compound, used in research of mitochondrial dysfunction. In its remarkable capacity as a mitochondrial uncoupler, it efficaciously facilitates energy dissipation while curbing ATP synthesis. Notably, this revolutionary compound exhibits immense promise in studying the burden of metabolic disorders like obesity and diabetes. Synonyms: 1-Dimethoxytrityloxy-3-O-[N-(2,4-dinitrophenyl)-3-N-aminopropyl-(triethyleneglycol)]-glyceryl-2-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; DNP-TEG Phosphoramidite. CAS No. 1027512-01-1. Molecular formula: C48H64N5O13P. Mole weight: 950.00.
A mixture solution of ultrapure dATP trisodium (1927-31-7), dCTP disodium (102783-51-7), dGTP trisodium (93919-41-6) and dTTP trisodium (18423-43-3). Used in PCR reaction. Synonyms: 4 x 100 mM (dATP, dCTP, dGTP, dTTP); 2'-Deoxyadenosine-5'-triphosphate, Sodium salt; 2'-Deoxycytidine-5'-triphosphate, Sodium salt; 2'-Deoxyguanosine-5'-triphosphate, Sodium salt; 2'-Deoxythymidine-5'-triphosphate, Sodium salt. Grades: ≥ 99 % by HPLC. Molecular formula: dATP 3Na: C10H13N5Na3O12P3; dCTP 2Na: C9H14N3Na2O13P3; dGTP 3Na: C10H13N5Na3O13P3; dTTP 3Na: C10H14N2Na3O14P3. Mole weight: dATP 3Na: 557.13; dCTP 2Na: 511.12; dGTP 3Na: 573.13; dTTP 3Na: 548.11.
dNTP Mix / 10 mM
An equimolar (10 nm) mixture solution of ultrapure dATP, dCTP, dGTP and dTTP. Synonyms: Premix of 10 mM dATP, dCTP, dGTP and dTTP; 2'-Deoxyadenosine 5'-triphosphate, Sodium salt; 2'-Deoxycytidine 5'-triphosphate, Sodium salt; 2'-Deoxyguanosine 5'-triphosphate, Sodium salt; 2'-Deoxythymidine 5'-triphosphate, Sodium salt. Grades: ≥ 99 % by HPLC. Molecular formula: C10H13N5O12P3(Anion); C9H13N3O13P3(Anion); C10H13N5O13P3(Anion); C10H14N2O14P3(Anion). Mole weight: 488.16 (Anion); 464.13 (Anion); 504.16 (Anion); 479.14 (Anion).
dNTP Mix / 25 mM
An equimolar (25 nm) mixture solution of ultrapure dATP, dCTP, dGTP and dTTP. Synonyms: Premix of 25 mM dATP, dCTP, dGTP and dTTP; 2'-Deoxyadenosine 5'-triphosphate, Sodium salt; 2'-Deoxycytidine 5'-triphosphate, Sodium salt; 2'-Deoxyguanosine 5'-triphosphate, Sodium salt; 2'-Deoxythymidine 5'-triphosphate, Sodium salt. Grades: ≥ 99 % by HPLC. Molecular formula: C10H13N5O12P3(Anion); C9H13N3O13P3(Anion); C10H13N5O13P3(Anion); C10H14N2O14P3(Anion). Mole weight: 488.16 (Anion); 464.13 (Anion); 504.16 (Anion); 479.14 (Anion).
dNTP Mix GCamplifier / 10 mM
Modified dNTP mixture that could be used for amplification of GC-rich sequences. Synonyms: Modified dNTP Mix for amplification of GC-rich sequences.
dNTP Mix incl. dUTP / 10 mM
An equimolar(10 nm) mixture solution of ultrapure dATP, dCTP, dGTP and dUTP. Synonyms: Premix of 10 mM dATP, dCTP, dGTP and 20 mM dUTP; 2'-Deoxyadenosine 5'-triphosphate, Sodium salt; 2'-Deoxycytidine 5'-triphosphate, Sodium salt; 2'-Deoxyguanosine 5'-triphosphate, Sodium salt; 2'-Deoxyuridine 5'-triphosphate, Sodium salt. Grades: ≥ 99 % by HPLC. Molecular formula: C10H13N5O12P3(Anion); C9H13N3O13P3(Anion); C10H13N5O13P3(Anion); C9H12N2O14P3(Anion). Mole weight: 488.16 (Anion); 464.13 (Anion); 504.16 (Anion); 465.12 (Anion).
dPTP
dPTP could be used in the studies of DNA polymerases (through interactions) and the generationg of a library of mutants. Synonyms: 2'-Deoxy-P-nucleoside-5'-Triphosphate. Grades: ≥ 95 % by HPLC. CAS No. 173964-83-5. Molecular formula: C11H14Na4N3O14P3. Mole weight: 597.15.
dT-Me Phosphoramidite
The dT-Me Phosphoramidite, a compound commonly utilized in the solid-phase synthesis of oligonucleotides incorporating methylated nucleosides, like 5-methylcytosine and N4-methylcytosine, has the propensity to improve the stability of RNA and DNA molecules. Therein lies the potential for a game-changing effect on the development of innovative treatments for challenging diseases such as cancer, viral infections or genetic disorders. Synonyms: 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-[(methyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 84416-85-3. Molecular formula: C38H48N3O8P. Mole weight: 705.79.
dTpCpp
dTpCpp is an extensively applied nucleotide analogue domain, exbibiting remarkable prospects in nucleic acid synthesand modification. The ingenious usage of dTpCpp extends to genetic investigations concerning the precise labeling of DNA and RNA at specific sites, thereby facilitating intricate investigations into replication, transcription and translation processes. Synonyms: dTMPCPP; 2'-Deoxythymidine-5'-[(α,β)-methyleno]triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C11H19N2O13P3(free acid). Mole weight: 480.20 (free acid).
dTpNHpp
dTpNHpp, a nucleotide analog employed in biomedical research, represents an intriguing prospect as an anti-cancer agent. As a potent and selective inhibitor of polo-like kinases (Plks), preclinical studies reveal its potential to bring about cell cycle arrest and stifle tumor growth. In fact, investigations into cancer therapy have even explored its viability in targeted drug delivery systems. Synonyms: dTMPNPP; 2'-Deoxythymidine-5'-[(α,β)-imido]triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 183584-80-7. Molecular formula: C10H14Na4N3O13P3. Mole weight: 569.14.
dTTPαS
dTTPαS is a modified nucleotide analogue used in enzymology and molecular biology research. It can be incorporated into DNA sequences during polymerase chain reaction (PCR) and is commonly used in site-directed mutagenesis studies. It has also been used in the study of DNA replication and repair mechanisms. Synonyms: 2'-Deoxythymidine-(α-thio)-triphosphate, Sodium salt (1 : 1 Mixture of Rp and Sp isomers). Grades: ≥ 95 % by HPLC. CAS No. 99749-43-6. Molecular formula: C10H17N2O13P3S.4Na. Mole weight: 586.19.
dTTP solution - Lithium Salt
dTTP could be used in the studies of DNA labeling reactions, polymerase chain reaction and sequencing/cycle sequencing analysis. Grades: ≥ 99 % by HPLC. Molecular formula: C10H17N2O14P3·xLi. Mole weight: 482.17 (free acid).
dTTP solution - Sodium Salt
Cas No. 3624-46-2.
dU-CPG 1000
dU-CPG 1000 is a remarkable synthetic modified nucleotide. With improved stability and effectiveness of nucleic acids, dU-CPG 1000 is more effective in fighting a range of diseases such as cancer and viral infections. Synonyms: 5'-Dimethoxytrityl-2'-deoxyUridine, 3'-succinoyl-long chain alkylamino-CPG 1000.
dUpCp
dUpCp, a nucleoside analogue hailed for its therapeutic potential in treating viral infections such as hepatitis C and HIV, has garnered attention for its capacity to inhibit viral replication and to stymie further infection. What's more, this potent analogous substance holds great promise in fighting cancer, with studies demonstrating its propensity to selectively trigger apoptosis in cancer cells. Although the ramifications of its usage as an antitumor agent call for further inquiry into its efficacy, it's an exciting prospect indeed. Synonyms: dUMPCP; 2'-Deoxyuridine-5'-[(α,β)-methyleno]diphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C10H16N2O10P2(free acid). Mole weight: 386.19 (free acid).
dUpCpp
dUpCpp - a chemical compound utilized in the field of biomedical research - holds promising potential as an enzyme activator which facilitates DNA and RNA replication. By augmenting the function of polymerases essential for viral replication, this unique substance presents a promising target for antiviral drug development. Furthermore, dUpCpp has been utilized to probe and unravel the mechanisms underlying the polymerization of DNA and RNA in a spectrum of systems. Synonyms: dUMPCPP; 2'-Deoxyuridine-5'-[(α,β)-methyleno]triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 170428-84-9. Molecular formula: C10H17N2O13P3.xNa. Mole weight: 466.17 (free acid).
dUpNHp
dUpNHp, a noteworthy biochemical research instrument, exhibits extensive applicability in the modification and examination of enzymatic activity within cells. Remarkably, its specificity in targeting and altering the activity of protein kinases and G proteins has proven invaluable within the realm of biomedicine, aiding in the study of prevalent diseases such as diabetes, cancer, and Alzheimer's whilst facilitating the development of new drugs targeted to combat them. Synonyms: dUMPNP;2'-Deoxyuridine-5'-[(α,β)-imido]diphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 178809-71-7. Molecular formula: C9H15N3O10P2.xNa. Mole weight: 387.17 (free acid).
dUpNHpp
dUpNHpp, a formidable small molecule inhibitor with potential therapeutic benefits, is a contender in the battle against cancer. Its mode of action rests on disrupting protein-protein interactions, resulting in the arrest of tumor growth. Ovarian and breast cancer, both notorious for their lethality, have been subject to clinical trials with auspicious outcomes. Synonyms: dUMPNPP;2'-Deoxyuridine-5'-[(α,β)-imido]triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 170428-86-1. Molecular formula: C9H16N3O13P3.xNa. Mole weight: 467.15 (free acid).
DyLight DY647 CEP
DyLight DY647 CEP is a fluorescent dye used for oligonucleotide labeling. Grades: ≥85%. Molecular formula: C47H63N4O5PS. Mole weight: 827.07.