BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| AZD-3514 | AZD-3514 is a potent androgen receptor downregulator with potential anticancer cancer activity. AZD3514 is being evaluated in a Phase I clinical trial in patients with castrate-resistant prostate cancer. Synonyms: AZD3514; AZD 3514; AZD-3514. Grades: 0.98. CAS No. 1240299-33-5. Molecular formula: C25H32F3N7O2. Mole weight: 519.56. |  |
| AZD-3759 hydrochloride | AZD-3759 hydrochloride is an effective, orally active and central nervous system-penetrant EGFR inhibitor. AZD-3759 hydrochloride induces cancer cell apoptosis. Synonyms: AZD3759 hydrochloride; Zorifertinib HCl; Zorifertinib hydrochloride; (R)-4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl 2,4-dimethylpiperazine-1-carboxylate hydrochloride. CAS No. 1626387-81-2. Molecular formula: C22H24Cl2FN5O3. Mole weight: 496.36. | |
| AZD3839 | AZD3839, also called CHEMBL2177913, as a potent BACE1 inhibitor it is a clinical candidate for the treatment of Alzheimer's disease. Studies indicate that the inhibition of BACE1 impedes the production of Aβ peptide. Synonyms: AZD3839; AZD-3839; AZD 3839. (3S)-3-[2-(difluoromethyl)pyridin-4-yl]-7-fluoro-3-(3-pyrimidin-5-ylphenyl)isoindol-1-amine; CHEMBL2177913; I8ID590133; UNII-I8ID590133; I8ID590133; SCHEMBL1358337; BDBM50398264; (1S)-1-(2-(Difluoromethyl)pyridin-4-yl)-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine; 1227163-84-9; 1H-Isoindol-3-amine, 1-(2-(difluoromethyl)-4-pyridinyl)-4-fluoro-1-(3-(5-pyrimidinyl)phenyl)-, (1S)-. CAS No. 1227163-84-9. Molecular formula: C24H16F3N5. Mole weight: 431.41. | |
| AZD 3988 | AZD 3988 is a selective and potent diacylglycerol O-acyltransferase (DGAT) enzyme inhibitor with IC50 value of 0.6 nM. It is selective for DGAT-1 over DGAT-2, cytochrome P450 enzymes and Kv11.1 (hERG). It suppresses adipose tissue TAG synthesis and triacylglyceride (TAG) plasma excursion in rats. It reduces body weight of diet-induced obese rats and may be used as a potential treatment for diabetes and other metabolic diseases. It is orally bioavailable and cell permeable. Synonyms: AZD 3988; AZD-3988; AZD3988; trans-4- [- [ [ [5- [ (3, 4-Difluorophenyl) amino] -1, 3, 4-oxadiazol-2-yl] carbonyl] amino] phenyl] cyclohexaneacetic acid. Grades: ≥98% by HPLC. CAS No. 892489-52-0. Molecular formula: C23H22F2N4O4. Mole weight: 456.44. | |
| AZD4017 | AZD4017 is a potent, selective, and orally bioavailable 11β-HSD1 inhibitor (11β-hydroxysteroid dehydrogenase type 1 inhibitor). Inhibition of 11β-HSD1 is an attractive mechanism for the treatment of obesity and other elements of the metabolic syndrome. Synonyms: AZD-4017; AZD 4017; (S)-2-(1-(5-(Cyclohexylcarbamoyl)-6-(propylthio)pyridin-2-yl)piperidin-3-yl)acetic acid. Grades: 96%. CAS No. 1024033-43-9. Molecular formula: C22H33N3O3S. Mole weight: 419.58. | |
| AZD4877 | AZD4877 is a synthetic kinesin spindle protein (KSP) inhibitor with potential antineoplastic activity. AZD4877 selectively inhibits microtubule motor protein KSP (also called kinesin-5 or Eg5), which may result in the inhibition of mitotic spindle assembly. Synonyms: AZD-4877; AZD 4877; (+)-N-(3-Aminopropyl)-N-(1-(5-benzyl-3-methyl-4-oxo-(1,2)thiazolo(5,4-d)pyrimidin-6-yl)-2-methylpropyl)-4-methylbenzamide. CAS No. 1176760-49-8. Molecular formula: C28H33N5O2S. Mole weight: 503.66. | |
| AZD-5597 | AZD-5597 is a potent CDK inhibitor with in vitro anti-proliferative effects against a range of cancer cell lines. AZD-5597 has excellent physiochemical properties and large margins against inhibition of CYP isoforms and the hERG ion channel. Synonyms: AZD 5597; AZD5597; Methanone, [4-[[5-fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-2-pyrimidinyl]amino]phenyl][(3S)-3-(methylamino)-1-pyrrolidinyl]-; [4-[[5-Fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-2-pyrimidinyl]amino]phenyl][(3S)-3-(methylamino)-1-pyrrolidinyl]methanone; (S)-(4-((5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone. Grades: >98%. CAS No. 924641-59-8. Molecular formula: C23H28FN7O. Mole weight: 437.52. | |
| AZD-5672 | AZD5672 is CCR5 receptor antagonist originated by AstraZeneca. In Jul 2009, Phase-II for Rheumatoid arthritis in USA was discontinued. Uses: Rheumatoid arthritis. Synonyms: AZD-5672; AZD 5672; AZD5672; UNII-61XQN688TW; (R) -N- (1- (3- (3, 5-difluorophenyl) -3- (4- (methylsulfonyl) phenyl) propyl) piperidin-4-yl) -N-ethyl-2- (4- (methylsulfonyl) phenyl) acetamide. Grades: 98%. CAS No. 780750-65-4. Molecular formula: C32H38F2N2O5S2. Mole weight: 632.79. | |
| AZD-6126 | AZD6126 is a water-soluble phosphate prodrug of N-acetylcolchinol with potential antiangiogenesis and antineoplastic activities. Synonyms: AZD6126; AZD 6126; N-Acetylcochinol-O-phosphate; (5S)-5-acetamido-9,10,11-trimethoxy-6,7-dihydro-5H-dibenzo[a,c][7]annulen-3-yl dihydrogen phosphate; N-[9,10,11-Trimethoxy-3-(phosphonooxy)-6,7-dihydro-5H-dibenzo[a,c][7]annulen-5-yl]ethanimidic acid. CAS No. 219923-05-4. Molecular formula: C20H24NO8P. Mole weight: 437.38. | |
| AZD-6280 | AZD-6280 is a selective GABAA(α2/3) receptor modulator for the treatment of generalized anxiety disorder. Synonyms: AZD6280; UNII-B9Z1OEH19D; AZD 6280; B9Z1OEH19D; CHEMBL1783256. Grades: 98%. CAS No. 942436-93-3. Molecular formula: C20H22N4O3. Mole weight: 366.4. | |
| AZD-7325 | AZD7325 is a high-affinity and selective modulator of the GABAA receptor system. Synonyms: AZD7325. Grades: 98%. CAS No. 942437-37-8. Molecular formula: C19H19FN4O2. Mole weight: 354.4. | |
| AZD7545 | AZD7545 is a potent PDHK inhibitor with IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2, respectively. Synonyms: AZD7545; AZD-7545; AZD 7545. Grades: >98%. CAS No. 252017-04-2. Molecular formula: C19H18ClF3N2O5S. Mole weight: 478.87. | |
| AZD7648 | AZD7648 is a potent and selective DNA-PK inhibitor with anti-tumor activity. Synonyms: AZD-7648; AZD 7648. Grades: 98%. CAS No. 2230820-11-6. Molecular formula: C18H20N8O2. Mole weight: 380.4. | |
| AZD7687 | AZD7687 is a potent and selective DGAT1 inhibitor with an IC50 value of 80 nM (hDGAT1). Synonyms: AZD7687; AZD 7687; AZD-7687. Grades: >98%. CAS No. 1166827-44-6. Molecular formula: C21H25N3O3. Mole weight: 367.44. | |
| AZD8329 | AZD8329 is a potent, selective 11β-HSD1 inhibitor (11β-hydroxysteroid dehydrogenase type 1 inhibitor) with reduced acyl glucuronide liability. AZD8329 demonstrates to have improved technical profile in terms of both solubility and pharmacokinetics. The extent of acyl glucuronidation was reduced through structural optimization of both the carboxylic acid and amide substituents, coupled with a reduction in lipophilicity leading to an overall increase in metabolic stability. Synonyms: AZD-8329; AZD 8329; 4-(4-((1r,3r,5r,7r)-adamantan-2-ylcarbamoyl)-5-(tert-butyl)-1H-pyrazol-1-yl)benzoic acid. Grades: 98%. CAS No. 1048668-70-7. Molecular formula: C25H31N3O3. Mole weight: 421.54. | |
| AZD8797 | AZD8797 is a selective allosteric non-competitive modulator of the human CX3CR1 receptor (Ki = 3.9 nM), binding CX3CR1 and effecting G-protein signalling and β-arrestin recruitment in a biased way. AZD8797 has a 720 fold selectivity for CX3CR1 receptor over the CXCR2 receptor, a 246-fold selectivity versus hCCR1 and 187-fold versus hCCR2 and no significant antagonism of the CCR4, CCR5, CCR6, CXCR3, and CXCR5 receptors. Synonyms: AZD8797; AZD-8797; AZD 8797; (2R)-2-[[2-amino-5-[(1S)-1-phenylethyl]sulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol. CAS No. 911715-90-7. Molecular formula: C19H25N5OS2. Mole weight: 403.56. | |
| AZD 9272 | AZD 9272 is a potent, long-acting and selective nervous system penetrant mGlu5 antagonist with IC50 values of 2.6 and 7.6 nM for rat and human receptors, respectively. It shows >3900-fold selectivity for mGlu5 over other mGlu receptors and shows discriminative effects in rats. It is orally bioavailable and brain penetrant. It has psychoactive and psychomimetic effects. Synonyms: AZD-9272; AZD 9272; AZD9272; 3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile; 3-(5-Fluoropyrid-2-yl)-5-(3-cyano-5-fluorophenyl)-1,2,4-oxadiazole. Grades: ≥98% by HPLC. CAS No. 327056-26-8. Molecular formula: C14H6F2N4O. Mole weight: 284.22. | |
| AZD9496 maleate | AZD9496 maleate is potent downregulator of estrogen receptor in breast carcinoma cells and also antagonise ERα with good oral pharmacokinetic properties. It is in collaboration with parexel initiates enrolment in a phase I trial in health volunteers in US. Synonyms: (Z)-but-2-enedioic acid;(E)-3-[3,5-difluoro-4-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]phenyl]prop-2-enoic acidAZD9496 (maleate); AZD 9496 (maleate); AZD-9496 (maleate). CAS No. 1639042-28-6. Molecular formula: C29H29F3N2O6. Mole weight: 558.55. | |
| AZ Dyrk1B 33 | AZ Dyrk1B 33 is a potent and selective ATP-competitive Dyrk1B kinase inhibitor with IC50 value of 7 nM. It shows better selectivity than AZ 191 and shows no off-target effects against a panel of 124 kinases tested. It displays distinct cellular effects when compared to DYRK1B knockdown through siRNA and has been demonstrated cellular in vitro activity. Synonyms: AZ-Dyrk1B-33; 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine. Grades: ≥98% by HPLC. CAS No. 1679330-37-0. Molecular formula: C19H16N4. Mole weight: 300.36. | |
| Azelaic acid dichloride | Azelaic acid dichloride (CAS# 123-98-8) is a useful research chemical. Synonyms: nonanedioyl dichloride. Grades: 95 %. CAS No. 123-98-8. Molecular formula: C9H14Cl2O2. Mole weight: 225.11. | |
| Azelaic Acid-Hydroxypropyl-beta-Cyclodextrin | Synonyms: Azelaic Acid-Hydroxypropyl-b-Cyclodextrin; Azelaic Acid-Hydroxypropyl-β-Cyclodextrin. | |
| Azelastine | Azelastine, a phthalazine derivative, is a potent, second-generation, selective, histamine antagonist used as a first line therapy of mild intermittent. Uses: An antihistamine and mast cell stabilizer. Synonyms: 1(2h)-phthalazinone,4-((4-chlorophenyl)methyl)-2-(hexahydro-1-methyl-1h-azepin; 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1-one. Grades: ≥98%. CAS No. 58581-89-8. Molecular formula: C22H24ClN3O. Mole weight: 381.9. | |
| Azepane-2-Carboxylic Acid | Synonyms: Azocane-2-carboxylic acid; Hexahydro-1H-azepine-2-carboxylic acid. Grades: 95%. CAS No. 5227-53-2. Molecular formula: C7H13NO2. Mole weight: 143.18. | |
| Azepexole hydrochloride | Azepexole hydrochloride is an agonist of α2-adrenergic receptors (α2-ARs). It induces sedation and reduces motor activity in mice and causes concentration-dependent inhibition of peristaltic contractions. Synonyms: 4H-Oxazolo[4,5-d]azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-, hydrochloride (1:1); 6-ethyl-4H,5H,6H,7H,8H-[1,3]oxazolo[4,5-d]azepin-2-amine hydrochloride. Grades: >98.0%. CAS No. 147663-20-5. Molecular formula: C9H16ClN3O. Mole weight: 217.7. | |
| Azetidine | Synonyms: Azacyclobutane; Trimethylene imine; Trimethylenimine; 1,3-Propylenimine. Grades: 98%. CAS No. 503-29-7. Molecular formula: C3H7N. Mole weight: 57.09. | |
| AZ-GHS-22 | AZ-GHS-22 is an orally-available Ghrelin receptor (GHS-R1a) inverse agonist (IC50 = 0.77 nM) with very low CNS exposure. Synonyms: AZ-GHS-22; AZ GHS-22; AZ-GHS 22; AZ GHS 22; AZGHS22; 2-chloro-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-morpholin-4-ylbenzamide. Grades: 98%. CAS No. 1143020-91-0. Molecular formula: C27H33ClN6O5S2. Mole weight: 621.17. | |
| Azidobenzene solution | Azidobenzene solution (CAS# 622-37-7) is a useful research chemical. Synonyms: azidobenzene. CAS No. 622-37-7. Molecular formula: C6H5N3. Mole weight: 119.12. | |
| Azidomethyl phenyl sulfide | Azidomethyl phenyl sulfide (CAS# 77422-70-9 ) is a useful research chemical. Synonyms: azidomethylsulfanylbenzene. Grades: > 97.0 % (LC). CAS No. 77422-70-9. Molecular formula: C7H7N3S. Mole weight: 165.22. | |
| Azido-mono-amide-DOTA-tris(t-Bu ester) | Synonyms: DOTA-(COOt-Bu)3-azide. CAS No. 1402795-92-9. Molecular formula: C31H58N8O7. Mole weight: 654.85. | |
| Azido-PEG10-amine | Azido-PEG10-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: N3-PEG10-CH2CH2NH2; 32-Azido-3,6,9,12,15,18,21,24,27,30-decaoxadotriacontan-1-amine; O-(2-Aminoethyl)-O-(2-azidoethyl)nonaethylene Glycol; N3-PEG10-NH2. Grades: >97%. CAS No. 912849-73-1. Molecular formula: C22H46N4O10. Mole weight: 526.62. | |
| Azido-PEG2-alcohol | Azido-PEG2-alcohol is a polyethylene glycol (PEG)-based PROTAC linker. Azido-PEG2-alcohol can be used in the synthesis of a series of PROTACs. Synonyms: 2-(2-azidoethoxy)ethanol; 2-(2-azidoethoxy)ethan-1-ol. Grades: >95%. CAS No. 139115-90-5. Molecular formula: C4H9N3O2. Mole weight: 131.13. | |
| Azido-PEG3-acetic acid | N3-PEG3-CH2COOH is a PROTAC linker, which refers to the alkyl/ether composition. N3-PEG3-CH2COOH can be used in the synthesis of a series of PROTACs. N3-PEG3-CH2COOH is a PEG derivative containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. Synonyms: Azido-PEG3-CH2CO2H;11-Azido-3,6,9-trioxaundecanoic Acid; N3-PEG3-CH2COOH; {2-[2-(2-Azidoethoxy)ethoxy]ethoxy}acetic acid; Acetic acid, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-; Azido-PEG3-CH2COOH. Grades: >95%. CAS No. 172531-37-2. Molecular formula: C8H15N3O5. Mole weight: 233.22. | |
| Azido-PEG3-amine | A PEG derivative, which contains a free amine that can be conjugated to biological molecules directly by an amide linkage (or via the corresponding isothiocyanate) and an azide that can be reduced to an amine for conjugation to other molecules. PEG derivatives are water soluble. Bifunctional water soluble compounds with flexible dimensions allow for conjugation of small molecules to proteins or molecular probes. 1-amino-11-azido-3,6,9-trioxaundecane can be reacted with small organic molecules for the synthesis of heterobifunctional compounds. It has been used to synthesize a mannose-fluorescein conjugate for the study of cell-surface mannose-specific lectins. Synonyms: Azide-PEG4-Amine;1-Amino-11-azido-3,6,9-trioxaundecane; Amino-PEG3-C2-Azido; 1-[2-(2-aminoethoxy)ethoxy]-2-(2-azidoethoxy)ethane; N3-PEG3-CH2CH2NH2; Ethanamine, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-; 11-Azido-3,6,9-trioxaundecan-1-amine; 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethan-1-amine. Grades: ≥95%. CAS No. 134179-38-7. Molecular formula: C8H18N4O3. Mole weight: 218.25. | |
| Azido-PEG4-acetic Acid | N33-TEG-COOH is a PROTAC linker containing four polyethylene glycol (PEG) units. N33-TEG-COOH is a PEG derivative containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. Synonyms: Azido-PEG4-CH2CO2H;Azido-PEG4-CH2COOH; N3-TEG-COOH; N3-PEG4-CH2COOH; 14-azido-3,6,9,12-tetraoxatetradecanoic acid; Acetic acid, 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]-; 14-azido-3,6,9,12-tetraoxatetradecan-1-oic acid. Grades: ≥95%. CAS No. 201467-81-4. Molecular formula: C10H19N3O6. Mole weight: 277.27. | |
| Azido-PEG4-Amine | N3-PEG4-C2-NH2 is a polyethylene glycol (PEG)-based PROTAC linker. N3-PEG4-C2-NH2 can be used in the synthesis of a series of PROTACs. N3-PEG4-C2-NH2 is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Synonyms: 14-Azido-3,6,9,12-tetraoxatetradecan-1-amine; O-(2-Aminoethyl)-O'-(2-azidoethyl)triethylene Glycol; N3-PEG4-C2-NH2; N3-PEG4-CH2CH2NH2; 14-Amino-3,6,9,12-tetraoxatetradecanyl Azide; 1-Amino-14-azido-3,6,9,12-tetraoxatetradecane. Grades: ≥95%. CAS No. 951671-92-4. Molecular formula: C10H22N4O4. Mole weight: 262.31. | |
| Azido-PEG5-amine | Azido-PEG5-amine is a polyethylene glycol (PEG)-based PROTAC linker. Azido-PEG5-amine can be used in the synthesis of a series of PROTACs. Synonyms: O-(2-Aminoethyl)-O'-(2-azidoethyl)tetraethylene Glycol; 17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine; N3-PEG5-CH2CH2NH2; N3-PEG5-NH2; 1-Amino-17-azido-3,6,9,12,15-pentaoxaheptadecane; 17-Azido-3,6,9,12,15-pentaoxaheptadecanamine. Grades: ≥95%. CAS No. 516493-93-9. Molecular formula: C12H26N4O5. Mole weight: 306.36. | |
| Azido-PEG5-azide | Azido-PEG5-azide is a polyethylene glycol (PEG)-based PROTAC linker. Azido-PEG5-azide can be used in the synthesis of a series of PROTACs. Uses: A cross-linking reagent. Synonyms: 3,6,9,12,15-PENTAOXAHEPTADECANE-1,17-DIYL BIS-AZIDE. Grades: >95%. CAS No. 356046-26-9. Molecular formula: C12H24N6O5. Mole weight: 332.36. | |
| Azido-PEG8-alcohol | O-(2-Azidoethyl)heptaethylene glycol (CAS# 352439-36-2) is used in the synthesis of heterobifunctionalized oligo(ethylene glycol) linkers for use in drug delivery. Uses: Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. in the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. monodisperse azide-peg8-alcohol (n3-peg8-oh) is a click chemistry reagent with an azide(n3) and a terminal hydroxyl (oh) group. the azide group is reactive with alkyne, bcn, dbco via click chemistry to yield a stable triazole linkage. the hydroxyl (oh) group enables further derivatization or replacement with other functional groups. Synonyms: N3-PEG8-OH; Azide-PEG8-alcohol; 2- [2- [2- [2- [2- [2- [2- (2-azidoethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethanol. Grades: >97%. CAS No. 352439-36-2. Molecular formula: C16H33N3O8. Mole weight: 395.45. | |
| Azido-PEG8-amine | Azido-PEG8-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol; N3-PEG8-CH2CH2NH2; Azido-PEG8-NH2; N3-PEG8-NH2; 26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosan-1-amine. Grades: ≥90%. CAS No. 857891-82-8. Molecular formula: C18H38N4O8. Mole weight: 438.52. | |
| Azido-Thalidomide | Azido-Thalidomide is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand thalidomide conjugated to an alkyl linker with terminal azide group. Synonyms: E3 ligase Ligand-Linker Conjugates 18; N-(4-azidobutyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide. Grades: ≥98%. CAS No. 2098488-36-7. Molecular formula: C19H20N6O6. Mole weight: 428.405. | |
| Azilsartan-d5 | Cas No. 1346599-45-8. | |
| Azimilide | Azimilide, also called as Stedicor, a chlorophentlturany compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels. Phase III. Synonyms: 1-[(E)-[5-(4-chlorophenyl)furan-2-yl]methylideneamino]-3-[4-(4-methylpiperazin-1-yl)butyl]imidazolidine-2,4-dione 1-(((5-(4-chlorophenyl)-2-furanyl)methylene)amino)-3-(4-(4-methyl-1-piperazinyl)butyl)-2,4-imidazolidinedione dihydrochloride 2,4-Imidazolidi. CAS No. 149908-53-2. Molecular formula: C23H28ClN5O3. Mole weight: 457.95. | |
| Azimilide dihydrochloride | A Kv11.1 (hERG) channel blocker. Azimilide is a class III antiarrhythmic drug and it can be used to control abnormal heart rhythms. Uses: Anti-arrhythmia agents. Synonyms: 1-[[[5-(4-Chlorophenyl)-2-furanyl]methylene]amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4-imidazolidinedione dihydrochloride. Grades: ≥97% by HPLC. CAS No. 149888-94-8. Molecular formula: C23H28ClN5O3.2HCl. Mole weight: 530.88. | |
| Azimsulfuron | Azimsulfuron is an acetolactate synthase inhibitor used as a herbicide for the control of a variety of broad-leaved and sedge weeds in paddy fields and other aquatic situations. Synonyms: N-((4,6-Dimethoxypyrimidin-2-yl)carbamoyl)-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide; DPX 47; DPX-A 8947; IN-A 894; A8947; A 8947; A-8947; 1H-Pyrazole-5-sulfonamide, N-[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-; 1-(4,6-Dimethoxypyrimidin-2-yl)-3-[1-methyl-4-(2-methyl-2H-tetrazol-5-yl)pyrazol-5-ylsulfonyl]urea. Grades: ≥95%. CAS No. 120162-55-2. Molecular formula: C13H16N10O5S. Mole weight: 424.40. | |
| AZM-475271 | AZM475271 is orally Src tyrosine kinase inhibitor with potential anticancer and antimetastatic activities. AZM475271 remarkably inhibits growth and metastasis of orthotopically implanted human pancreatic carcinoma cells in nude mice. AZM475271 suppresses tumor growth and metastasis in vitro and in vivo potentially by anti-angiogenic mechanisms. Synonyms: AZM475271; AZM-475271; AZM 475271. Grades: 0.98. CAS No. 476159-98-5. Molecular formula: C23H27ClN4O3. Mole weight: 442.94. | |
| Azodicarboxylic dimorpholide | Azodicarboxylic dimorpholide (CAS# 10465-82-4 ) is a useful research chemical. Synonyms: (NE)-N-(morpholine-4-carbonylimino)morpholine-4-carboxamide. CAS No. 10465-82-4. Molecular formula: C10H16N4O4. Mole weight: 256.26. | |
| AzoLPA Ammonium salt | AzoLPA is embedded with an azobenzene photoswitch which enables the optical control of LPA receptor activation. The light-induced cis-form shows greater activation of LPA receptors than its dark-adapted trans-form. Lysophosphatidic acid (LPA) is an extracellular signaling molecule that activates LPA1-6 receptors. These receptors are particularly important in the nervous, cardiovascular, reproductive, gastrointestinal and pulmonary systems. Synonyms: 1- (E) -4- (4- ( (4-butylphenyl) diazenyl) phenyl) butanoyl]-2-hydroxy-sn-glycero-3-phosphate (ammonium salt). Grades: >99%. CAS No. 2389048-52-4. Molecular formula: C23H34N3O7P. Mole weight: 495.51. | |
| BBQ-650-DT CEP | BBQ-650-DT CEP is a revolutionary chemical amalgamation employed with an aim to precisely target cancerous cells. Its exceptionally selective inhibition explicitly curtails the activity of an intricate protein implicated in the pernicious development of tumors. Synonyms: 5'-Dimethoxytrityloxy-5-[6-(9-[4-nitro-2',5'-dimethoxyazobenz-4'-yldiazo]-julolidin-8-oxy)-hexylamidoethyl-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: 95%. CAS No. 905554-46-3. Molecular formula: C76H89N12O15P. Mole weight: 1441.57. | |
| β-Exotoxin | β-Exotoxin is a thermostable metabolite produced by some strains of Bacillus thuringiensis. β-Exotoxin can be used to screen and quantify indigenous thuringiensin-producing Bacillus thuringiensis isolates. β-Exotoxin can destroy cells or disrupte normal cellular metabolism to damage the host. Synonyms: O-5'-Deoxyadenosin-5'-yl-(5'?4)-O-α-D-glucopyranosyl-(1?2)-D-allaric Acid 4-(Dihydrogen Phosphate); Di Beta; NSC 197177; Thuringiensin; Thuringiensin A; Thurintox; Exotoxin. CAS No. 23526-02-5. Molecular formula: C22H32N5O19P. Mole weight: 701.49. | |
| β γ-methyleneadenosine 5'-Triphosphate Disodium Salt | Beta Gamma-methyleneadenosine 5'-Triphosphate Disodium Salt is a useful building block in the synthesis of various pharmaceuticals. Synonyms: 5'-Adenylic Acid Anhydride with Methylenediphosphonic Acid Disodium Salt; Anhydride of 5'-Adenylic Acid with Methylenediphosphonic Acid Di-Na Salt; Methylenedi-phosphonic Acid Anhydride with 5'-adenylic Acid Disodium Salt. CAS No. 7414-56-4. Molecular formula: C11H16N5Na2O12P3. Mole weight: 549.17. | |
| β-L-2'-Deoxyadenosine | β-L-2'-Deoxyadenosine, a vital chemical compound, is veritably an epitome of excellence when it comes to biomedical research. Its usage in exploring the impact of specific drugs on DNA replication and repair is unprecedented. What's more, it helps curb the growth of malignant cells, elucidating its significance as a potential anti-cancer drug. The procurement of this compound can be facilitated from various distinguished chemical suppliers, making the entire process efficient and hassle-free. Grades: ≥ 98% by HPLC. Molecular formula: C10H13N5O3. Mole weight: 251.24. | |
| β-L-2'-Deoxycytidine | β-L-2'-Deoxycytidine, a nucleoside analog employed in antiviral drug synthesis, has exhibited potential in combating viral infections such as hepatitis C. Additionally, it has proven useful in DNA methyltransferase inhibition for cancer research, providing a breakthrough in the search for new therapeutic treatments. Its unique and invaluable structure is a prime example of β-L-2'-Deoxycytidine's contributions to the ever-evolving world of medicine. Grades: ≥ 98% by HPLC. Molecular formula: C9H13N3O4. Mole weight: 227.22. | |
| β-L-2'-Deoxyguanosine | β-L-2'-Deoxyguanosine is a versatile pharmaceutical compound, finding myriad applications in the research of diverse ailments. Serving as a pivotal precursor for nucleotide-based compounds, this compound effectively aids in studying viral afflictions, like HIV and hepatitis B. Grades: ≥ 98% by HPLC. Molecular formula: C10H13N5O4. Mole weight: 267.24. | |
| β-L-2'-Deoxythymidine | β-L-2'-Deoxythymidine is an essential nucleoside analog, holding immense potential in the biomedical sector for its application in the development of groundbreaking antiviral drugs, primarily targeting a wide range of viral infections. By exhibiting an exceptional affinity towards thymidine kinase enzymes, it embodies a pivotal role in substantially impeding viral replication. Synonyms: Telbivudine. Grades: ≥ 98% by HPLC. Molecular formula: C10H14N2O5. Mole weight: 242.23. | |
| β-L-2'-Deoxyuridine | β-L-2'-Deoxyuridine is a multifaceted, remarkable compound product renowned for its boundless utility in studying viral infections and cancer. Serving as an indispensable antiviral drug, it diligently thwarts the nefarious replication strategy deployed by DNA viruses. Grades: ≥ 98% by HPLC. Molecular formula: C9H12N2O5. Mole weight: 228.2. | |
| β-L-Adenosine | β-L-Adenosine is a versatile biochemical compound extensively employed in the biomedical sector for advanced research studies, showcasing a profound significance in probing its exceptional efficacy against a gamut of ailments, including cancer, viral infections, as well as autoimmune disorders. Synonyms: L-Adenosine; L-rA; Beta-L-adenosine; (2S,3S,4R,5S)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 9-beta-L-Ribofuranosyladenine; 9-(b-L-Ribofuranosyl)adenine; 9-beta-L-Ribofuranosyl-9H-purine-6-amine. Grades: ≥97% by HPLC. CAS No. 3080-29-3. Molecular formula: C10H13N5O4. Mole weight: 267.24. | |
| β-L-Cytidine | β-L-Cytidine, a vital nucleoside analogue extensively used in the cure of viral infections, especially herpes simplex virus (HSV) alongside respiratory syncytial virus (RSV). Additionally, it serves as a constituent for the synthesis of vital biological entities, RNA and DNA, holding immense prominence in biomedical research. Grades: ≥ 98% by HPLC. Molecular formula: C9H13N3O5. Mole weight: 243.22. | |
| β-L-Guanosine | β-L-Guanosine is a nucleoside analog employed in the biomedical sector, used in the research of cancers, viral infections and autoimmune disorders. By incorporating into DNA or RNA, thereby impeding their synthesis and dismantling vital cellular mechanisms, this compound exerts its influence. Grades: ≥ 98% by HPLC. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
| β-L-Inosine | β-L-Inosine, a nucleoside precursor, finds extensive usage in biomedicine, playing a vital role in treating multiple medical conditions including cancer, viral infections, and autoimmune disorders. Studies have uncovered its antitumor and immunomodulatory effects, fueling its popularity as a potential remedy for cancer. Its immune function-boosting capabilities and inflammation-reducing properties further cement its position as a promising therapeutic agent in autoimmune disorders. Grades: ≥ 98% by HPLC. Molecular formula: C10H12N4O5. Mole weight: 268.23. | |
| β-L-Thymidine (riboside) | β-L-Thymidine (riboside), a nucleoside analogue, exhibits antiviral properties by inhibiting viral replication and displays potential therapeutic applications in DNA-related diseases such as cancer and genetic disorders. Moreover, recent research highlights its promising role in treating neurodegenerative diseases. Grades: ≥ 98% by HPLC. Molecular formula: C10H14N2O6. Mole weight: 258.23. | |
| β-L-Uridine | β-L-Uridine is a nucleoside derivative used in biomedical research. It acts as a precursor to synthesize RNA and has application in reactivating depleted dopamine levels in Parkinson's disease. Grades: ≥ 98% by HPLC. Molecular formula: C9H12N2O6. Mole weight: 244.2. | |
| β-NADPH Tetrasodium Salt Hydrate | One of the biologically active forms of nicotinic acid. Differs from NAD by an additional phosphate group at the 2'-position of the adenosine moiety. Serves as a coenzyme of hydrogenases and dehydrogenases. Present in living cells primarily in the reduced form (NADPH) and is involved in synthetic reactions. Synonyms: 2'-(Dihydrogen Phosphate) 5'-(Trihydrogen Pyrophosphate)adenosine 5'5'-Ester 1,4-Dihydro-1-β-D-ribofuranosylnicotinamide Tetrasodium Salt Hydrate;β-NADPH; 2'-NADPH Hydrate; Coenzyme II Reduced Tetrasodium Salt Hydrate; Triphosphopyridine Nucleotide Reduced Tetrasodium Salt Hydrate; Dihydronicotinamide Adenine Dinucleotide Phosphate Tetrasodium Salt Hydrate. Grades: 95%. Molecular formula: C21H26N7Na4O17P3 XH2O. Mole weight: 833.35. | |
| Beta-Nicotinamide Adenine Dinucleotide Sodium Salt | A metabolite of Nicotine,which is a potent parasympathomimetic stimulant. Synonyms: β-DPN, β-NAD, Coenzyme 1, Cozymase, DPN, Diphosphopyridine nucleotide, NAD, Nadide. Grades: > 95%. CAS No. 20111-18-6. Molecular formula: C21H26N7O14P2. Na. Mole weight: 662.43 22.99. | |
| β-Nicotinamide Adenine Dinucleotide Sodium Salt Hydrate | β-Nicotinamide Adenine Dinucleotide is a coeznyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate group. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins. Synonyms: Adenosine 5'-(Trihydrogen Diphosphate), P'?5'-Ester with 3-(Aminocarbonyl)-1-β-D-ribofuranosylpyridinium Hydroxide Sodium Salt Hydrate; Adenine-nicotinamide Dinucleotide Sodium Salt Hydrate; CO-I Sodium Salt Hydrate; Codehydrase I Sodium Salt Hydrate; Codehydrogenase I Sodium Salt Hydrate; Coenzyme I Sodium Salt Hydrate; Cozymase I Sodium Salt Hydrate; DPN Sodium Salt Hydrate; Diphosphopyridine Nucleotide Sodium Salt Hydrate; Enzopride Sodium Salt Hydrate; NAD Sodium Salt Hydrate; NAD+ Sodium Salt Hydrate; NSC 20272 Sodium Salt Hydrate; Nadide Sodium Salt Hydrate; Nicotinamide-adenine Dinucleotide Sodium Salt Hydrate; Oxidized diphosphopyridine Nucleotide Sodium Salt Hydrate; β-Diphosphopyridine Nucleotide Sodium Salt Hydrate; β-NAD Sodium Salt Hydrate; β-NAD+ Sodium Salt Hydrate. Grades: 95%. Molecular formula: C21H26N7NaO14P2 X(H2O). Mole weight: 685.41. | |
| β-Nicotinic Acid Mononucleotide | A nucleotide of nicotinic acid which is produced from quinolinic acid by quinolinate phosphoribosyltransferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH. Synonyms: 3-Carboxy-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium Inner Salt; 3-Carboxy-1-β-D-ribofuranosylpyridinium Hydroxide 5'-Phosphate Inner Salt; Nicotinate Mononucleotide; Nicotinate Ribonucleotide; Nicotinic Acid Ribonucleotide; Nicotinic Acid Ribotide; Nicotinic Mononucleotide; β-NaMN. Grades: 95%. CAS No. 321-02-8. Molecular formula: C11H14NO9P. Mole weight: 335.2. | |
| Binodenoson | Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A2A receptor agonist. It is used to diagnose coronary artery disease. Uses: Purinergic p1 receptor agonists. Synonyms: 2- (Cyclohexylmethylidenehydrazino) adenosine; 2-(2-(Cyclohexylmethylene)diazanyl)-9-beta-D-ribofuranosyl-9H-purin-6-amine; (2R,3R,4S,5R)-2-(6-Amino-2-(2-(cyclohexylmethylene)hydrazinyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 144348-08-3. Molecular formula: C17H25N7O4. Mole weight: 391.42. | |
| Biotin-11-CTP | Biotin-11-CTP is an indispensable compound in research of various diseases, widely employed as a substrate for DNA and RNA labeling. It notably facilitates the detection of intricate DNA or RNA sequences. Synonyms: Biotin-X-5-Propargylamino-CTP; γ-[N-(Biotin-6-amino-hexanoyl)]-5-propargylamino-cytidine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C28H44N7O17P3S (free acid). Mole weight: 875.67 (free acid). | |
| Biotin-11-dATP | Biotin-11-dATP is a biotinylated deoxyadenosine triphosphate analogue used in DNA labeling and detection assays. It plays an important role in biomedical research for diagnosis, prognostic evaluation, and treatment of diseases such as cancer. Biotin-11-dATP can be incorporated by DNA polymerases into newly synthesized strands during PCR amplification or DNA sequencing, and then used to analyze DNA structure, function and regulation. Synonyms: γ-[N-(Biotin-6-amino-hexanoyl)]-7-propargylamino-2'-deoxy-7-deaza-adenosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C30H45N8O15P3S (free acid). Mole weight: 882.71 (free acid). | |
| Biotin-11-dCTP | Biotin-11-dCTP is an essential compound assuming a pivotal role in exploring the intricate processes of DNA replication. Functioning as an indispensible indicator, it facilitates the discernment of biotinylated entities through the utilization of streptavidin-based analyses. Synonyms: Biotin-X-5-Propargylamino-dCTP; γ-[N-(Biotin-6-amino-hexanoyl)]-5-propargylamino-2'-deoxycytidine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 136632-30-9. Molecular formula: C28H44N7O16P3S (free acid). Mole weight: 859.67 (free acid). | |
| Biotin-11-ddATP | Biotin-11-ddATP is an indispensable compound in the biomedical field, serving as a remarkable instrument for exploring the intricacies of DNA replication. It stands as a prevalent modified nucleotide analog that remarkably fosters DNA sequencing and labeling methodologies. Synonyms: γ-[N-(Biotin-6-amino-hexanoyl)]-7-propargylamino-2',3'-dideoxy7-deaza-adenosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C30H45N8O14P3S (free acid). Mole weight: 866.71 (free acid). | |
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