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γ-[(6-Aminohexyl)imido]-dGTP - ATTO-647N
γ-[(6-Aminohexyl)imido]-dGTP - ATTO-647N is a fluorescent nucleotide analog used as a fundamental tool for DNA labeling and tracking during diverse biomedical applications. This distinct characteristic enables the exploration of DNA replication, DNA-protein interactions and DNA sequencing. Synonyms: γ-[(6-Aminohexyl)-imido]-2'-deoxyguanosine-5'-triphosphate, labeled with ATTO-647N, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C16H30N7O12P3- ATTO 647N (free acid). Mole weight: 1232.37 (free acid).
γ-[(6-Aminohexyl)imido]-dGTP - Cy3
γ-[(6-Aminohexyl)imido]-dGTP - Cy3 is a fluorescent nucleotide analog commonly used in biomedical research. This product is frequently employed in experiments involving DNA labeling or detection, such as fluorescence in situ hybridization (FISH). with Cy3 fluorescent dye, it enables visual detection and localization of DNA sequences associated with specific drugs or diseases. Synonyms: γ-[(6-Aminohexyl)-imido]-2'-deoxyguanosine-5'-triphosphate, labeled with Cy3, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C47H66N9O19P3S2(free acid). Mole weight: 1218.23 (free acid).
γ-[(6-Aminohexyl)imido]-dGTP - Cy5
γ-[(6-Aminohexyl)imido]-dGTP - Cy5, a nucleotide analog, is adeptly employed in biomedical research to detect both DNA and RNA precisely. Its fluorescent properties are quite valuable in applications like PCR and DNA sequencing, making it easy to pinpoint specific sequences. This powerful tool also has applications in diagnosing and treating various illnesses, including cancer. Clearly, this well-researched product offers a significant boost to scientific endeavors. Synonyms: γ-[(6-Aminohexyl)-imido]-2'-deoxyguanosine-5'-triphosphate, labeled with Cy5, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C49H68N9O19P3S2(free acid). Mole weight: 1244.16 (free acid).
γ-[(6-Aminohexyl)-imido]-dTTP
γ-[(6-Aminohexyl)-imido]-dTTP is a vital constituent employed in DNA synthesis within the biomedical sector assuming the role of an exceedingly efficient DNA polymerase substrate facilitating precise replication during PCR amplification. Synonyms: γ-[(6-Aminohexyl)-imido]-2'-deoxythymidine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C16H31N4O13P3(free acid). Mole weight: 580.36 (free acid).
γ-[(6-Aminohexyl)-imido]-dUTP
γ-[(6-Aminohexyl)-imido]-dUTP is a nucleotide found in molecular biology research dedicated to DNA sequencing and labeling, serving as a crucial reagent in enzymatic labeling of DNA oligonucleotides. This modified nucleotide can also aid in the investigation of DNA-protein interactions implicated in diseases, such as genetic disorders and cancer. Synonyms: γ-[(6-Aminohexyl)-imido]-2'-deoxyuridine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C15H29N4O13P3(free acid). Mole weight: 566.33 (free acid).
γ-[(6-Aminohexyl)-imido]-GTP
γ-[(6-Aminohexyl)-imido]-GTP, a compound utilized in the biomedical industry for studying G protein-coupled receptors (GPCRs) and their signaling pathways, is instrumental in investigating GTP binding and hydrolysis effects on GPCR functions. Moreover, it enhances the identification of likely therapeutic targets for diseases such as cancer, obesity, and diabetes. Synonyms: γ-[(6-Aminohexyl)-imido]-guanosine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C16H30N7O13P3(free acid). Mole weight: 621.37 (free acid).
γ-(6-Aminohexyl)-N6-Benzyl-ATP
γ-(6-Aminohexyl)-N6-Benzyl-ATP, a biochemical compound utilized in biomedicine, serves as a substrate for a multitude of kinases engaged in protein phosphorylation, proffering potential in investigating specific ailments, such as cancer and hereditary sensory neuropathy type 1. Employing this product may facilitate comprehending cellular signaling pathways and ultimately advance the creation of novel therapeutics. Synonyms: γ-(6-Aminohexyl)-N6-benzyl-adenosine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C23H35N6O13P3(free acid). Mole weight: 696.48 (free acid).
γ-(6-Aminohexyl)-N6-Benzyl-ATP - ATTO-647N
γ-(6-Aminohexyl)-N6-Benzyl-ATP - ATTO-647N is a fluorescent dye used for cell imaging and analysis in the biomedical industry. It is commonly employed in molecular biology and drug discovery research. This product finds extensive applications in studying ATP-dependent biological processes, including DNA replication, transcription and signal transduction pathways. with superior brightness and photostability, it facilitates high-resolution imaging and accurate quantification of cellular activities related to ATP metabolism. Synonyms: γ-(6-Aminohexyl)-N; -benzyl-adenosine-5'-triphosphate, labeled with ATTO 647N, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C23H35N6O13P3- ATTO 647N (free acid). Mole weight: 1324.34 (free acid).
γ-(6-Azidohexyl)-ATP
γ-(6-Azidohexyl)-ATP is a chemical compound that finds its application in the exploratory world of biomedicine as an essential photoaffinity labeling reagent concept for studying energy transduction systems in organisms. Furthermore, it has immense potential in the field of ATP synthesis analogs, directed towards treating various diseases that are allied with ATP metabolism, such as diabetes and cardiovascular diseases. Synonyms: γ-(6-Azidohexyl)-adenosine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C16H27N8O13P3(free acid). Mole weight: 632.35 (free acid).
γ-[(6-Azidohexyl)-imido]-ATP
γ-[(6-Azidohexyl)-imido]-ATP, bestowed with intriguing compound, propelling an astute exploration encompassing ATPase activity and nucleotide-binding entities. Remarkably, this polymorphic compound orchestrates a profound examination concerning pharmaceutical interplay, protein-protein amity and enzymatic machinations, dynamically propelling the frontier of therapeutic evolution and pathological research. Synonyms: γ-[(6-Azidohexyl)-imido]-adenosine-5'-triphosphate. Grades: ≥ 95 %. Molecular formula: C16H28N9O12P3(free acid). Mole weight: 631.37 (free acid).
γ-[(8-Aminooctyl)-imido]-2-Hydroxy-ATP
γ-[(8-Aminooctyl)-imido]-2-Hydroxy-ATP, a formidable and discriminating agonist for the P2Y11 receptor, a G protein-coupled receptor activated by ATP, exhibits potential for various immune-related conditions including chronic lymphocytic leukemia and rheumatoid arthritis. Its multifaceted properties as an immune modulator correspond to manifold roles, rendering it a promising therapeutic agent in the battle against immune-related maladies. Synonyms: γ-[(8-Aminooctyl)-imido]-2-hydroxy-adenosine-5'-triphosphate; γ-[(8-Aminooctyl)-imido]-iso-GTP. Grades: ≥ 95 % by HPLC. Molecular formula: C18H34N7O13P3(free acid). Mole weight: 649.42 (free acid).
γ-[(8-Aminooctyl)-imido]-8-Oxo-GTP
Gamma-[(8-Aminooctyl)-imido]-8-Oxo-GTP is an important compound utilized in the field of biomedical research to investigate the intricate interactions between G proteins and their signaling pathways. Moreover, it is also extensively employed in the study of diseases associated with G protein dysfunction, encompassing cancer, neurological disorders, and cardiovascular disorders. Synonyms: γ-[(8-Aminooctyl)-imido]-8-oxo-guanosine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C18H34N7O14P3(free acid). Mole weight: 665.42 (free acid).
γ-[(8-Aminooctyl)-imido]-ATP
γ-[(8-Aminooctyl)-imido]-ATP is a compound product used in the research of various diseases. This compound acts as a potent inhibitor of enzymatic reactions involving ATP, particularly those related to cell signaling and energy metabolism. Its research applications include targeting cancer cells, as well as managing autoimmune disorders and metabolic diseases. Synonyms: γ-[(8-Aminooctyl)-imido]-adenosine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C18H34N7O12P3(free acid). Mole weight: 633.42 (free acid).
γ-[(8-Aminooctyl)-imido]-CTP
γ-[(8-Aminooctyl)-imido]-CTP, a biochemical compound, functions as a substrate for enzymes essential for DNA synthesis and repair. Considerably employed in in vitro research for studying DNA replication and transcription and scrutinizing the aftermath of diverse drugs, γ-[(8-Aminooctyl)-imido]-CTP has an extensive range of potential therapeutic applications. Notably, it can be utilized for treating cancer and other ailments caused by glitches in DNA damage and repair mechanisms. Synonyms: γ-[(8-Aminooctyl)-imido]-cytidine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C17H34N5O13P3(free acid). Mole weight: 609.40 (free acid).
γ-[(8-Aminooctyl)-imido]-dCTP
γ-[(8-Aminooctyl)-imido]-dCTP, an esteemed modified nucleotide, finds varied biomedical applications. As a substrate for DNA polymerases, it facilitates exploration of DNA replication and repair, laying foundations for diagnostic tool development for detection of cancer and infectious diseases. These medicinal breakthroughs often employ the potential of this modified nucleotide in gene therapy for treatment of diseases including cystic fibrosis. Synonyms: γ-[(8-Aminooctyl)-imido]-2'-deoxycytidine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C17H34N5O12P3(free acid). Mole weight: 593.40 (free acid).
γ-[(8-Aminooctyl)-imido]-dUTP
γ-[(8-Aminooctyl)-imido]-dUTP, a modified nucleotide with an 8-carbon linker, exhibits great potential in molecular biology applications. Labeling DNA with fluorescent dyes or biotin had never been so easy! This versatile and dynamic molecule has been demonstrated to be highly effective in a wide spectrum of exercises including DNA sequencing and Nucleic Acid amplification. Its applications even extend to the study of DNA-protein interactions and imaging! Synonyms: γ-[(8-Aminooctyl)-imido]-2'-deoxyuridine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C17H33N4O13P3(free acid). Mole weight: 594.38 (free acid).
γ-[(8-Aminooctyl)-imido]-GTP
γ-[(8-Aminooctyl)-imido]-GTP is an essential biomolecule employed, exhibiting its prowess as a formidable and discriminating inhibitor specifically targeting GTPases implicated in cancer and neurological afflictions. Synonyms: γ-[(8-Aminooctyl)-imido]-guanosine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C18H34N7O13P3(free acid). Mole weight: 649.42 (free acid).
γ-[(8-Aminooctyl)-imido]-ITP
γ-[(8-Aminooctyl)-imido]-ITP, a biomedicine research compound, finds frequent use in investigations examining purinergic signaling and platelet biology, while simultaneously offering potential as a therapy for various platelet disorders. Synonyms: γ-[(8-Aminooctyl)-imido]-inosine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C18H33N6O13P3(free acid). Mole weight: 634.41 (free acid).
γ-[(8-Aminooctyl)-imido]-XTP
γ-[(8-Aminooctyl)-imido]-XTP, a biochemical reagent utilized for studying enzymes involved in RNA synthesis and processing, mimics ATP's structure and has demonstrated compatibility as a substrate for RNA polymerases. This versatile compound enables research on ribonucleases and ATP-dependent RNA helicases. Moreover, its utility extends to the study of the HIV-1 reverse transcriptase enzyme. Synonyms: γ-[(8-Aminooctyl)-imido]-xanthosine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C18H33N6O14P3(free acid). Mole weight: 650.41 (free acid).
γ-Aminophenyl-ATP
γ-Aminophenyl-ATP, a substrate analog, is widely utilized in biochemical research to investigate ATPases' activity. Such enzymes encompass a cohesive family responsible for expediting ATP hydrolysis. Furthermore, numerous studies have implicated γ-Aminophenyl-ATP in modulating the ABC transporter protein, P-glycoprotein. This protein, known for multidrug resistance, remains a potent candidate for future drug development. Synonyms: Adenosine-5'-[γ-(4-aminophenyl)]triphosphate. Grades: ≥ 95 % by HPLC. CAS No. 37866-02-7. Molecular formula: C16H21N6O13P3(free acid). Mole weight: 598.29 (free acid).
γ-Aminophenyl-m7GTP
γ-Aminophenyl-m7GTP is a crucial compound used in the biomedical industry for research and development purposes. It is commonly employed for studying molecular interactions between RNA and proteins, specifically in relation to the process of mRNA capping. Widely used in drug discovery, this compound plays a vital role in the development of novel therapeutic strategies targeting diseases such as cancer and viral infections. Synonyms: 7-Methylguanosine-5'-[γ-(4-aminophenyl)]triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C17H23N6O14P3(free acid). Mole weight: 628.05 (free acid).
γ-[Ethyl-CONH-(PEG4)]-ATP-Biotin
γ-[Ethyl-CONH-(PEG4)]-ATP-Biotin is a biochemical product that serves as an ATP analog and a biotinylating agent in biomedical research. It is commonly used to label and detect ATP-binding proteins in various biochemical assays and studies. Additionally, the product can also be used as a substrate to study the function and regulation of ATPases and kinases. Synonyms: γ-[Ethyl-CONH-(PEG4)]-Adenosine-5'-triphosphate-Biotin. Grades: ≥ 95 % by HPLC. Molecular formula: C33H56N9O20P3S (free acid). Mole weight: 1023.83 (free acid).
γ-PEG8-ATP-Biotin
γ-PEG8-ATP-Biotin, a nucleotide conjugate highly versatile in biomedical applications, ranging from enzymatic assays to protein target detection, is a potent label for biological molecule tracking in cell-based assays. This versatile affinity tag demonstrates immense potential for investigating various diseases and drug development, making it an essential component in scientific research. Synonyms: γ-PEG8-Adenosine-5'-triphosphate-Biotin. Grades: ≥ 95 % by HPLC. Molecular formula: C36H63N8O22P3S (free acid). Mole weight: 1084.91 (free acid).
γ-Propargyl-ATP
γ-Propargyl-ATP is an indispensable biomolecular compound functioning as a formidable hindrance to deoxyribonucleic acid synthesis, as well as a potent modifier of proteins. Its intrinsic value unfolds in the study against myriad malignant neoplasms and infectious maladies. Synonyms: Adenosine-5'-[γ-(propargyl)]triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C13H18N5O13P3(free acid). Mole weight: 545.23 (free acid).
γ-[(Propargyl)-imido]-ATP
γ-[(Propargyl)-imido]-ATP is a remarkably specialized product with applications aimed at studying the devastating impact of neurodegenerative afflictions. with unadulterated composition, it diligently engages with the intricate adenosine triphosphate (ATP) receptors, thereby augmenting synaptic transmission and fortifying the fundamental energy metabolism within cellular components. Synonyms: Adenosine-5'-[γ-(propargyl)-imido]triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C13H19N6O12P3(free acid). Mole weight: 544.24 (free acid).
GDPβS
GDPβS has been found to exhibit activities as an inhibitor of G-coupled protein. Synonyms: Guanosine-5'-(β-thio)-diphosphate, Sodium salt. Grades: ≥ 90 % by HPLC. Molecular formula: C10H15N5O10P2S (free acid). Mole weight: 459.26 (free acid).
GDP-D-glucose sodium salt
Cas No. 103301-72-0.
GDP-Gel / GDP-Agarose
GDP-Gel is the GDP coupled to a polymeric gel by the terminal phosphate, which can be used in the affinity purification of fucosyltransferases. Synonyms: Guanosine- 5'- O- diphosphate, immobilized on a polymeric matrix.
GDP-L-fucose
GDP-L-fucose is a pivotal biomolecule acting as a precursory compound to facilitate the synthesis of fucose-containing glycoconjugates implicated in diverse cellular phenomena. Its exceptional significance lies in the research of glycosylation patterns, evaluation of protein functioning repercussions and investigation into possible therapeutic approaches targeting conditions like cancer and inflammation. Synonyms: GDP-b-L-fucose; Guanosine 5-diphospho-b-L-fucose; GDP-Fucose; Guanosine diphosphofucose; Guanosine 5'-diphospho-beta-L-fucopyranose; guanosine 5'-[3-(6-deoxy-beta-L-galactopyranosyl) dihydrogen diphosphate]. Grades: ≥90%. CAS No. 15839-70-0. Molecular formula: C16H25N5O15P2. Mole weight: 589.34.
Gemcitabine-5'-diphosphate
A diphosphorylated derivative of Gemcitabine and has been found to exhibit potent activities as an inhibitor of ribonucleotide reductases (RNRs). Synonyms: 2'-deoxy-2',2'-difluorocytidine 5'-(trihydrogen diphosphate). Grades: ≥ 95 % by HPLC. CAS No. 116371-66-5. Molecular formula: C9H13F2N3O10P2. Mole weight: 423.16.
Gemcitabine-5'-triphosphate
A triphosphorylated derivative of Gemcitabine and has been found to exhibit potent activities as a cytotoxic agent and induce apoptosis. Synonyms: 2',2'-Difluorocytidine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C9H14N3O13P3F2. Mole weight: 503.14.
Gemcitabine Monophosphate
A monophosphorylated derivative of Gemcitabine and has been found to exhibit potent activities as a cytotoxic agent and induce apoptosis. Synonyms: 2',2'-difluorodeoxycytidine Monophosphate; Gemcitabine 5'-phosphate. Grades: ≥ 95 % by HPLC. CAS No. 116371-67-6. Molecular formula: C9H12F2N3O7P. Mole weight: 343.18.
GMP
Guanosine 5'-monophosphate has been found to be useful in studies of modulation of glutamatergic neurotransmission. Synonyms: Guanosine-5'-monophosphate; 5'-Guanylic Acid. Grades: ≥ 95 % by HPLC. Molecular formula: C10H14N5O8P. Mole weight: 363.22.
GMPαS
GMPαS, a synthesized protein of biotechnological application, is utilized in the biomedical sector for the purpose of investigation into the sprawling domain of inflammatory bowel disease (IBD). This recombinant compound fosters an effective anti-inflammatory response via the suppression of cytokine production associated with the onset of IBD. Additionally, GMPαS's therapeutic possibilities are gaining increasing scientific traction as a potential target for treating a gamut of autoimmune and underlying inflammatory maladies. Synonyms: Guanosine-5'-(α-thio)-monophosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C10H14N5O7PS (free acid). Mole weight: 379.28 (free acid).
GP2G
GP2G is an extraordinary pharmaceutical, finding applications in studying numerous autoimmune afflictions encompassing rheumatoid arthritand multiple sclerosis. Its mechanism of action entails robust immunosuppression alongside notable anti-inflammatory properties. Synonyms: P1-(5'-Guanosyl)-P2-(5'-guanosyl)-diphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C20H26N10O15P2(free acid). Mole weight: 708.43 (free acid).
GP2(Nic)
GP3G
GP3G is a kind of diguanosine polyphosphate, could be found in human plasma. Synonyms: G(5')ppp(5')G; P1-(Guanosyl) P3-(5'-(guanosyl))triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C20H27N10O18P3. Mole weight: 788.41.
GP3G (Unmethylated Cap Analog)
GP3G is a kind of diguanosine polyphosphate, could be found in human plasma. Synonyms: G(5')ppp(5')G Cap Analog; Diguanosine triphosphate; Diguanosine-5'-triphosphate; P1-(Guanosyl) P3-(5'-(guanosyl))triphosphate; CAP. Grades: ≥ 95 % by HPLC. CAS No. 6674-45-9. Molecular formula: C20H27N10O18P3. Mole weight: 788.41.
GP4G
GP4G, a naturally occurring compound found in green tea and seaweed, is a multifunctional ingredient commonly employed as a dietary supplement and cosmetic product ingredient. Various investigations indicate its significant role in augmenting skin cell metabolism and safeguarding against ultraviolet radiation-induced harm. Moreover, studies exhibit the potential of GP4G in bolstering brain function and exercise performance. The compound is also a promising candidate in treating afflictions such as Alzheimer's disease and stroke. Synonyms: P1-(5'-Guanosyl)-P4-(5'-guanosyl)-tetraphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C20H28N10O21P4. Mole weight: 868.39.
Gp4U
Gp4U is an innovative and groundbreaking biomedical compound, used for studying diverse malignancies such as breast, lung and colon cancer. Synonyms: P1- (5'- Guanosyl)- P4- (5'- uridyl)- tetraphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 79695-25-3. Molecular formula: C19H27N7O22P4 (free acid). Mole weight: 829.4 (free acid).
GpAp
GpAp is a synthetic linear dinucleotide not binding to the c-diGMP-I riboswitch. Synonyms: Guanylyl- (3' -≥ 5')- adenosine- 3'- O- phosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 17332-08-0. Molecular formula: C20H26N10O14P2. Mole weight: 692.4.
GpCpp
GpCpp is an analogue of GTP and could be used as a stabilizer in some microtubule cryoelectron microscopy studies. Uses: Antiviral agents. Synonyms: GMPCPP; Guanosine-5'-[(α,β)-methyleno]triphosphate. Grades: ≥ 95 % by HPLC. CAS No. 14997-54-7. Molecular formula: C11H18N5O13P3. Mole weight: 521.21.
GppNH2
GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPN; Guanosine-5'-(β-amino)-diphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C10H16N6O10P2. Mole weight: 442.21.
GppNHp - Tetralithium salt
The tetrasodium salt form of GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPNP; Guanosine-5'-[( β,γ )-imido]triphosphate, Tetralithium salt; GMPPNHP. Grades: ≥ 95 % by HPLC. CAS No. 64564-03-0. Molecular formula: C10H13N6ONa413P3. Mole weight: 611.13.
GTP-γ-AmNS
GTP-γ-AmNS is a fluorescent analogue of GTP used for the determination of enzymes specialized to cleave α/β-phosphodiester bonds. Synonyms: Guanosine- 5'- O- triphosphoro- γ- 1- (5- sulfonic acid)naphthylamidate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 76724-84-0. Molecular formula: C20H23N6O16P3S (free acid). Mole weight: 728.4 (free acid).
GTPγS
GTPγS is a stable G-protein-activating (GTP) analog. The physiological actions of GTPgammaS includestimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes. Synonyms: Guanosine-5'-(γ-thio)-triphosphate, Tetralithium salt; Guanosine-5'-(3-thio)-triphosphate; Guanosine-5'-(3-thiotriphosphate). Grades: ≥ 90 % by HPLC, contains < 10 % GDP. CAS No. 94825-44-2. Molecular formula: C10H16N5O13P3S (free acid). Mole weight: 539.24 (free acid).
Guanosine
Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Synonyms: 2-Amino-1,9-dihydro-9-β-D-ribofuranosyl-6H-purin-6-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-β-D-ribofuranosyl-; DL-Guanosine; Guanine ribonucleoside; Guanine, 9-β-D-ribofuranosyl-; Inosine, 2-amino-; NSC 19994; Vernine; β-D-Ribofuranoside, guanine-9. Grades: ≥95%. CAS No. 118-00-3. Molecular formula: C10H13N5O5. Mole weight: 283.24.
Guanosine-2',5'-bisphosphate
Guanosine-2',5'-bisphosphate is a paramount molecule in the biomedical sector, exhibiting its indispensability by serving as a substrate for enzymes participating in signal transduction pathways, thereby playing a seminal role in vital cellular processes. This multifunctional product finds extensive application in scientific investigations pertaining to G-proteins, kinases and ion channels, enabling researchers to gain deeper insights into cellular functions. Synonyms: Guanosine-2',5'-bisphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C10H15N5O11P2(free acid). Mole weight: 443.20 (free acid).
Guanosine-3',5'-bisphosphate
Guanosine-3',5'-bisphosphate is a robust and indispensable molecule within the biomedical sector is adeptly modulates intricate cellular proceedings. Exhibiting the prowess of a secondary messenger, this compound intricately navigates intracellular signaling pathways is adroitly orchestrating a symphony of diverse biological functionalities encompassing gene expression, protein synthesis and cellular proliferation. Synonyms: (pGp); Guanosine-3',5'-bisphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C10H15N5O11P2(free acid). Mole weight: 443.20 (free acid).
Guanosine 3',5'-cyclic monophosphate
Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'-and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. 3',5'-cyclic GMP is a 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine. It has a role as a plant metabolite, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a guanyl ribonucleotide and a 3',5'-cyclic purine nucleotide. It is a conjugate acid of a 3',5'-cyclic GMP(1-). Synonyms: D-Guanosine 3',5'-cyclic monophosphate; 3',5'-cyclic GMP; 2-Amino-6-oxo-6,9-dihydro-1H-purine 3-oxide; guanine-3-N-oxide; 2-Amino-1,7-dihydro-6H-purin-6-one 3-oxide; Cyclic guanosine monophosphate; 9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino-1H-purin-6-one. Grades: ≥ 95%. CAS No. 7665-99-8. Molecular formula: C10H12N5O7P. Mole weight: 345.21.
Guanosine 3',5'-Diphosphate Tetralithium Salt
Guanosine 3',5'-Diphosphate Tetralithium Salt is a drug transporter on the arachnoid barrier cells that contribute to blood-cerebrospinal fluid barrier. Synonyms: Guanosine 3',5'-Bis(dihydrogen Phosphate) Tetralithium Salt; 3',5'-Diphosphoguanosine Tetralithium Salt. CAS No. 55612-39-0. Molecular formula: C10H11Li4N5O11P2. Mole weight: 466.93.
Guanosine-3',5'-pentaphosphat
Guanosine 3'-diphosphate 5'-triphosphate
Guanosine 3'-diphosphate 5'-triphosphate is a pivotal molecule entwined in signal transduction and protein synthesis, emerging as an indispensable compound. It exert its prowess as an enthusiastic bestower of energy during translation, while adroitly orchestrating the activity of G-proteins. It assumes a role in unraveling the enigmatic dynamics of enzyme kinetics, nucleotide metabolism and the meticulous dissection of ailments synonymous to G-protein signaling cascades. Synonyms: Guanosine-3',5'-pentaphosphate; Guanosine pentaphosphate; pppGpp; Guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate); ( (2R, 3S, 4R, 5R) -5- (2-amino-6-oxo-1, 6-dihydro-9H-purin-9-yl) -4-hydroxy-3- ( (hydroxy (phosphonooxy) phosphoryl) oxy) tetrahydrofuran-2-yl) methyl tetrahydrogen triphosphate; 5'-Triphosphoguanosine 3'-diphosphate. Grades: ≥95%. CAS No. 38918-96-6. Molecular formula: C10H18N5O20P5. Mole weight: 683.14.
Guanosine 5'-monophosphate is a purine ribonucleoside 5'-monophosphate having guanine as the nucleobase. It has a role as a metabolite, a biomarker, an Escherichia coli metabolite and a mouse metabolite. It is a guanosine 5'-phosphate and a purine ribonucleoside 5'-monophosphate. It is a conjugate acid of a guanosine 5'-monophosphate(2-). Guanosine 5'-monophosphate. A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. Synonyms: 5-Guanylic Acid; 5'-GMP; GMP; Guanidine Monophosphate; Guanosine 5'-Phosphate; Guanosine 5'-Phosphoric Acid; Guanosine Monophosphate; Guanylic Acid. Grades: ≥95%. CAS No. 85-32-5. Molecular formula: C10H14N5O8P. Mole weight: 363.22.
Guanosine-5'-O-(1-Thiotriphosphate)
Guanosine-5'-O-(1-Thiotriphosphate) emerges as an indispensable compound within the biomedical industry serving as a substrate for diverse enzymatic reactions and a biophysical research instrument. Throughout investigations concerning GTP-binding proteins, signal transduction pathways and protein-protein interactions, its vital participation becomes apparent. Moreover, its utilization enables the exploration of key mechanisms involved in debilitating diseases, exemplified by cancer and neurological disorders. Synonyms: Alpha Thiol GTP; 1-Thio-GTP; Guanosine-5'-Rp-Alpha-Thio-Triphosphate. Grades: ≥90% by AX-HPLC. CAS No. 81570-50-5. Molecular formula: C10H16N5O13P3S. Mole weight: 539.3.
Guanosine 5'-O-(2-Thiodiphosphate) Trilithium Salt
Guanosine 5'-O-(2-Thiodiphosphate) Trilithium Salt is a GDP analog which could inhibits G-protein activation. Synonyms: 5'-Guanylic acid, monoanhydride with phosphorothioic acid, trilithium salt; EINECS 308-328-9; Guanosine 5'-O-(2-thiodiphosphate) trilithium salt; trilithium; [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dioxidophosphinothioyl phosphate; Guanosine 5'-[beta-thio]diphosphate trilithium salt; GDP-beta-S-Li3; GDPbetaS trilithium salt; Guanosine 5'-O-(2-Thiodiphosphate), Trilithium Salt; MFCD00057735; Guanosine 5-O-(2-thiodiphosphate)trilithium salt; Guanosine,5'-esterwith thiodiphosphoric acid([(ho)2p(o)]2s)(9ci); Guanosine 5'-[beta-thio]diphosphate trilithium salt, >=85% (HPLC), powder. CAS No. 97952-36-8. Molecular formula: C10H12Li3N5O10P2S. Mole weight: 477.07.
Guanosine 5'-(tetrahydrogen triphosphate) Sodium Salt (>80%)
Guanosine 5'-(tetrahydrogen triphosphate) Trisodium Salt, is the salt form of GTP, which is a substrate for the RNA synthesis during the transcription process or DNA during DNA replication. It is also used as an energy source for protein synthesis and gluconeogenesis. Synonyms: 5'-GTP Sodium Salt; Sodium GTP. Grades: 80%. CAS No. 24905-71-3. Molecular formula: C10H16N5O14P3 xNa. Mole weight: 523.18.
Guanosine 5'-triphosphate
Guanosine triphosphate (GTP) is a guanine nucleotide containing three phosphate groups esterified to the sugar moiety. GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. Synonyms: D-Guanosine 5'-triphosphate; Guanosine triphosphate; Guanosine 5'-triphosphoric acid; pppG; guanosine 5'-O-(triphosphate); [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate. Grades: ≥98% by AX-HPLC. CAS No. 86-01-1. Molecular formula: C10H16N5O14P3. Mole weight: 523.18.
Guanosine 5-triphosphate
Guanosine (N-iBu)
Guanosine (N-iBu) is an indispensable compound employed in biomedical investigation and pharmacological advancements assuming a pivotal stance in studying an assortment of ailments encompassing cancer, neurodegenerative conditions and viral afflictions. Grades: ≥ 98% by HPLC. Molecular formula: C14H19N5O6. Mole weight: 353.33.
Guanosine (N-PAC)
Guanosine (N-PAC), a petite yet significant molecule, finds extensive applications in the biomedical industry. Its capacity to serve as a precursor in the synthesis of nucleotides, facilitating the biosynthesis of DNA and RNA, is unparalleled. The treatment of viral infections, particularly hepatitis C and dengue fever, is another area where Guanosine (N-PAC) has proved its efficacy. Interestingly, studies reveal its potential in addressing neurological disorders like Parkinson's disease - a promising avenue indeed. Grades: ≥ 98% by HPLC. Molecular formula: C18H19N5O7. Mole weight: 417.37.
Guanosine (N-Phenyl acetyl)
Guanosine (N-Phenyl acetyl) is a chemical compound used in biomedical research for its potential anti-cancer properties. It has shown promise in inhibiting cell growth and inducing apoptosis in cancer cells. It is also used in the development of certain antiviral drugs due to its ability to inhibit viral replication. Grades: ≥ 98% by HPLC. Molecular formula: C18H19N5O6. Mole weight: 401.37.
guanylyl-3',5'-cytidine
Guanylyl-3',5'-cytidine, a biochemical compound, is a valuable tool in the biomedical industry for delving deep into the intricacies of RNA capping mechanisms. It mimics guanosine 5-triphosphate (GTP), a naturally occurring molecule, and is utilized to investigate the cellular processes of various RNA viruses, including hepatitis C virus (HCV). Furthermore, guanylyl-3',5'-cytidine holds the promise of therapeutic benefits for HCV and other RNA viral infections. Synonyms: Guanylyl-(3',5')-cytidine; GpC RNA Dinucleotide (5'-3'); Cytidylyl-(5'->3')-guanosine. Grades: 95%. CAS No. 4785-04-0. Molecular formula: C19H25N8O12P. Mole weight: 588.40.
Guanylyl-3'-5'-cytidine ammonium salt
Guanylyl-3'-5'-cytidine ammonium salt is an indispensable compound with sector assuming a pivotal role in the research of multifarious afflictions such as neoplastic disorders and rampant viral invasions. By virtue of its indispensability, this invaluable compound serves as an indispensable implement for nucleotide synthesand RNA molecular construction. Synonyms: GpC; [5-(2-amino-6-oxo-3H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl][5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate,azane. Grades: 98%. CAS No. 98046-67-4. Molecular formula: C19H25N8O12P·NH3. Mole weight: 605.46.
Guanylyl-(3'-5')-guanosine
Guanylyl-(3'-5')-guanosine is a highly significant compound extensively employed in biomedical research, emerging as an indispensable player in signal transduction. Its pivotal role lies in its capacity to function as a second messenger molecule, especially in the modulation of cyclic GMP levels. Diverse cellular phenomena, encompassing vasodilation, neurotransmission and immune responses is are meticulously investigated utilizing this molecule to scrutinize the cGMP-dependent pathways. Synonyms: GpG RNA Dinucleotide (5'-3'). Grades: ≥95% by AX-HPLC. CAS No. 3353-33-1. Molecular formula: C20H25N10O12P. Mole weight: 628.40.
Guanylyl-3'-5'-uridine ammonium salt
Guanylyl-3'-5'-uridine ammonium salt is an essential biomedical ingredient, playing a pivotal role in mRNA synthesand facilitates genetic information translation. Its diverse applications span the biomedical field, notably encompassing mRNA-related disease researchs and the advancement of mRNA-based therapies. Synonyms: GpU; [5-(2-amino-6-oxo-3H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl][5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate,azane. Grades: 98%. CAS No. 41547-83-5. Molecular formula: C19H24N7O13P·NH3. Mole weight: 606.45.
Hexaethylene glycol phosphoramidite
Hexaethylene glycol phosphoramidite is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required. Synonyms: 18-O-(4,4'-Dimethoxytrityl)-hexaethylene glycol-1-[[(2-cyanoethyl)-(N,N-diisopropyl)]- Phosphoramidite; 1,1-bis(4-methoxyphenyl)-1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl (2-cyanoethyl) diisopropylphosphoramidite; Spacer 18 Phosphoramidite. Grades: ≥95.0%. CAS No. 125607-09-2. Molecular formula: C42H61N2O10P. Mole weight: 784.91.
Idoxuridine
5-Iodo-2'-deoxyuridine is a nucleoside analog that can be incorporated into viral DNA replication to treat herpes simplex keratitis. Uses: 5-iodo-2'-deoxyuridine is a nucleoside analog treat herpes simplex keratitis. Synonyms: 5-Iodo-2'-deoxyuridine; IDU; 2'-Deoxy-5-iodouridine; 5-Iodo-2'-deoxy-D-uridine; 1-(2-Deoxy-β-D-ribofuranosyl)-5-iodouracil; IUdR; Dendrid; Emanil; NSC 39661; Ophthalmadine; Herpesil; Herpidu; Herplex; Stoxil; Stoxip; Synmiol; Virudox. Grades: ≥98% by HPLC. CAS No. 54-42-2. Molecular formula: C9H11IN2O5. Mole weight: 354.10.
IDP
IDP, or inhibitor of DNA binding protein, is an essential protein that modulates the cell cycle, exerting a significant influence on cancer growth and proliferation. Progress towards developing IDP inhibitors as promising cancer therapeutics has been made, especially with regards to breast, colon, and pancreatic cancer. Synonyms: Inosine-5'-diphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C10H14N4O11P2(free acid). Mole weight: 428.18 (free acid).