BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| IMP | Inosine monophosphate, a versatile nucleotide, plays a pivotal role in the synthesis of RNA and DNA. Its diverse applications span from treating neuropathic pain and viral infection to serving as a therapeutic agent for gout. Beyond its pharmacological benefits, IMP is also found in many nutritional supplements, promising a wealth of health-promoting effects. At a cellular level, IMP exhibits potent anti-tumor and anti-inflammatory properties, opening up new avenues of research in this domain. Synonyms: Inosine-5'-monophosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 108250-70-0. Molecular formula: C10H13N4O8P (free acid). Mole weight: 348.20 (free acid). |  |
| Inosine-3',5'-cyclic-monophosphate | Inosine-3',5'-cyclic-monophosphate, a multifaceted signaling molecule, participates in diverse physiological processes including muscle contraction, neurotransmission, and ion channel regulation. This intriguing biomolecule has captivated scientific attention for its prospective therapeutic applications in neurological disorders, cardiovascular pathologies, and malignant conditions. Its aptitude in promoting neuroprotection and augmenting synaptic plasticity renders it a fascinating candidate for tackling the symptoms of Alzheimer's and various other neurodegenerative afflictions. Synonyms: 3',5'-Cyclic IMP. CAS No. 3545-76-4. Molecular formula: C10H11N4O7P. Mole weight: 330.19. | |
| Inosine-3',5'-cyclic Monophosphate Sodium Salt | Inosine-3',5'-cyclic monophosphate is a cyclic nucleotide that stimulates steroidogenesis by adrenocortical cells in rats. Inosine-3',5'-cyclic monophosphate also stimulates insulin secretion in hamster pancreas cells. Synonyms: Inosine Cyclic 3',5'-(Hydrogen Phosphate) Sodium Salt; Inosine 3',5'-Phosphate (Cyclic) Sodium Salt; Inosine Cyclic 3',5'-(Hydrogen Phosphate) Monosodium Salt; 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin Inosine Deriv.; 3',5'-cIMP Sodium Salt. Grades: 95%. CAS No. 41092-64-2. Molecular formula: C10H10N4NaO7P. Mole weight: 352.17. | |
| Inosine-5'-diphosphate | Inosine-5-diphosphate is a nucleoside diphosphate that is indubitably vital to cellular energy metabolism. It serves as a crucial substrate for enzymes involved in purine salvage pathways and contributes to the biosynthesis of purine nucleotides. Additionally, IDP has been linked to an array of signal transduction pathways and has the ability to modulate the activity of ion channels. There is promising potential for IDP to become an effective therapy option for diseases characterized by purine metabolism imbalances. Synonyms: Inosine diphosphate; Riboxin; Inosine 5'-pyrophosphate; IDP; riboxine; Inosine pyrophosphate; Inosine 5'-(trihydrogen diphosphate); 9-{5-O-[Hydroxy(phosphonooxy)phosphoryl]-β-D-ribofuranosyl}-9H-purin-6-ol; 5'-IDP; Inosine 5'-diphosphoric acid. Grades: ≥98% by HPLC. CAS No. 86-04-4. Molecular formula: C10H14N4O11P2. Mole weight: 428.19. | |
| Inosine 5'-diphosphate disodium salt | Inosine 5'-diphosphate disodium salt, a pivotal biochemical compound sought after in the biomedical industry, assumes an indispensable function in the generation and modulation of intracellular signaling molecules. Given its implication in cellular energy metabolism and nucleotide biosynthesis, this particular product finds application in ameliorating distinct metabolic disorders and neurodegenerative ailments. Synonyms: Inosine 5'-(trihydrogen diphosphate), disodium salt. Grades: 95%. CAS No. 54735-61-4. Molecular formula: C10H12N4O11P2·2Na. Mole weight: 472.15. | |
| Inosine 5'-monophosphate | Inosine 5'-monophosphate (IMP) is a profound molecular compound magnanimously entrusted with the profound responsibility of studying an extensive array of afflictions, encompassing neurologic dysfunctions, cardiac anomalies and immunological imperfections. Synonyms: Inosinic acid; IMP; 1-5'-P; inosinemonophosphate; [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate. Grades: ≥ 98%. CAS No. 131-99-7. Molecular formula: C10H13N4O8P. Mole weight: 348.20. | |
| Inosine-5'-monophosphate disodium salt octahydrate | Inosine-5'-monophosphate disodium salt octahydrate, a pivotal compound in biomedicine, holds immense significance due to its involvement in the biosynthesis of purine and nucleoside derivatives. Synonyms: 5'-IMP-Na2; Disodium 5'-inosinate octahydrate. Grades: 98%. CAS No. 20813-76-7. Molecular formula: C10H27N4Na2O16P. Mole weight: 536.29. | |
| Inosine 5'-(tetrahydrogen triphosphate) | Inosine 5'-(tetrahydrogen triphosphate) is a bioactive organic molecule with immense therapeutic potential in addressing an array of ailments- from cancer, metabolic afflictions, to viral infections. It functions as an indispensable precursor for purine nucleotide synthesis, thereby stimulating ATP production, augmenting cellular energy reserves, and activating immune cells such as T-cells to ramp up response to various intruders. Synonyms: ITP; Hypoxanthine; Inosine-5'-Triphosphate. Grades: ≥98% by AX-HPLC. CAS No. 132-06-9. Molecular formula: C10H15N4O14P3. Mole weight: 508.10. | |
| Inosine 5'-triphosphate disodium salt | Inosine 5'-triphosphate disodium salt, a nucleotide precursor to ATP, is a pivotal biochemistry molecule. Its utility in probing purine nucleotides' influence on enzyme activity, coupled with its broad applicability in enzymatic and biochemical assays, render it a versatile research tool. Its involvement in hindering leukemia occurrence through DNA incorporation and synthesis blockade further underscores its therapeutic potential. Synonyms: INOSINE-5-TRIPHOSPHORIC ACID SODIUM SALT; INOSINE-5'-TRIPHOSPHATE TRISODIUM SALT; sodium((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-2-yl)methyl dihydrogentriphosphate. Grades: ≥ 95%. CAS No. 36051-67-9. Molecular formula: C10H13N4O14P3·2Na. Mole weight: 552.13. | |
| INS37217 | INS-37217, also known as Denufosol, is a long- acting P2Y2 receptor agonist potentially for the treatment of cystic fibrosis. INS-37217 exhibits an EC50 of ~10 μM for P2Y2 receptor activation. Synonyms: INS37217; INS 37217; INS-37217; Uridine 5'-(pentahydrogen tetraphosphate)?, P'''?5'-ester with 2'-deoxycytidine, sodium salt (1:4). CAS No. 318250-11-2. Molecular formula: C18H27N5Na4O21P4. Mole weight: 865.28. | |
| Ip5I | Ip5I is an anatagonist of P2X1/P2X3 receptor. Synonyms: P1, P5- Di- (inosine- 5')- pentaphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1294478-76-4. Molecular formula: C20H27N8O24P5 (free acid). Mole weight: 918.3 (free acid). | |
| IppNHp | IppNHp is a synthetic peptide that is commonly used in pharmaceutical research to study voltage-gated calcium channels and their role in diseases such as epilepsy and chronic pain. It can also be used in the development of new drugs targeting these channels. Synonyms: (IMPPNP); Inosine-5'-[(β,γ)-imido]triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C10H16N5O13P3(free acid). Mole weight: 507.18 (free acid). | |
| Isocytidine Triphosphate Triethylamine Salt | Isocytidine triphosphate triethylamine salt, a fundamental constituent in the biomedical industry, represents a paramount importance. It finds utility within the domain of nucleic acid synthesis, acting as a substrate for DNA and RNA polymerases. Indispensable in combating specific viral ailments and malignancies, this compound displays its worth by impeding viral replication and disrupting tumor proliferation. Synonyms: 4(1H)-Pyrimidinone, 2-amino-1-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-, triethylamine salt (1:x); 2-Amino-1-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-4 (1H) -pyrimidinone Triethylamine Salt; ((2R,3S,4R,5R)-5-(2-amino-4-oxopyrimidin-1(4H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate triethylamine salt. Molecular formula: C9H16N3O14P3.xC6H15N. Mole weight: 483.16 (free base). | |
| Isoguanosine (N/N-diisobutylformamidine) | Isoguanosine is also known as N/N-diisobutylformamidine, renowned for its remarkable antiviral attributes. This exceptional compound serves as a pivotal compound in studying RNA viruses, predominantly hepatitis C and influenza, which afflict the human population. Its effectiveness lies in the potent inhibition of viral replication, thus rendering it an indispensable instrument for advanced antiviral drug investigation and development. Grades: ≥ 98% by HPLC. Molecular formula: C19H30N6O5. Mole weight: 422.48. | |
| Isoguanosine Triacetate | Isoguanosine Triacetate is a compound useful in organic synthesis. Synonyms: 1,2-Dihydro-2-oxo-adenosine 2',3',5'-Triacetate; 9-β-D-Ribofuranosylisoguanine Triacetate; Crotonosid Triacetate; Crotonoside Triacetate; Isoguanine Riboside Triacetate; 2-Hydroxyadenosine Triacetate. Grades: 98%. CAS No. 173098-06-1. Molecular formula: C16H19N5O8. Mole weight: 409.35. | |
| Isoprinosine | Isoprinosine is a complex of acetaminobenzoic acid, dimethylaminoisopropanol, and inosine with the ratio of 3:3:1. It is an immunomodulatory drug approved in several countries for the treatment of viral infections. Synonyms: Inosine pranobex; Inosiplex; Delimmun; Imunovir. Grades: ≥98% (HPLC). CAS No. 36703-88-5. Molecular formula: C52H78N10O17. Mole weight: 1115.249. | |
| ITPγS | ITPγS, a renowned pharmaceutical product extensively employed in the domain of biomedicine, serves as an invaluable tool for investigating and comprehending cellular responses orchestrated by IP3 receptors, including intricate processes like calcium ion release and intracellular signaling cascades. The non-hydrolyzable analogue of inositol trisphosphate (IP3), ITPγS assumes the role of a specialized agonist for G protein-coupled receptor signaling pathways. Synonyms: Inosine-5'-(γ-thio)-triphosphate, Sodium salt. Grades: ≥ 90 % by HPLC. CAS No. 77065-87-3. Molecular formula: C10H15N4O13P3S (free acid). Mole weight: 524.22 (free acid). | |
| Kinetin Riboside | It is used as an anticancer and antiviral agent. Synonyms: Furfurylaminopurineriboside; N6-Furfuryladenosine; 6-Furfurylaminopurine Riboside, N-(2-Furanylmethyl)adenosine; NSC 120958; Ribosylkinetin; Kinetin-9-riboside; N6-(2-Furanyl-methyl)adenosine; N-(2-Furylmethyl)-9-pentofuranosyl-9H-purin-6-amine. Grades: ≥95%. CAS No. 4338-47-0. Molecular formula: C15H17N5O5. Mole weight: 347.33. | |
| Lagociclovir | Lagociclovir is a prodrug of 3'-fluoro-2',3'-dideoxyguanosine with high oral bioavailability in humans and potent activity against HBV. Uses: Antiviral agents. Synonyms: MIV-210; MIV 210; MIV210; 3'-FddG; Fddguo; Lagociclovir. Grades: >98%. CAS No. 92562-88-4. Molecular formula: C10H12FN5O3. Mole weight: 269.23. | |
| Lamivudine 5'-monophosphate ammonium salt | Lamivudine 5'-monophosphate ammonium salt astutely presents itself as a paramount pharmaceutical compound, which aptly grapples with the dire repercussions of viral infections. Functioning as a formidable nucleotide analog reverse transcriptase inhibitor, its unwavering focus lies in the meticulous targeting of both HIV-1 and hepatitis B virus infections. Uses: A metabolite of lamivudine (l172500). Synonyms: 4-Amino-1-[(2R,5S)-2-[(phosphonooxy)methyl]-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone ammonium salt; 2',3'-Dideoxy-3'-thia-cytidine-5'-monophosphate; Ammonium [(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl]methyl hydrogen phosphate. Grades: 95%. CAS No. 1187058-40-7. Molecular formula: C8H15N4O6PS. Mole weight: 326.27. | |
| Lamivudine Diphosphate Ammonium Salt | Lamivudine Diphosphate Ammonium Salt is a metabolite of Lamivudine, a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has also been used for treatment of chronic hepatitis B. Synonyms: P-[[(2R,5S)-5-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl] Ester Diphosphoric Acid Ammonium Salt; Diphosphoric acid, [(2R,5S)-5-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl ester, diammonium salt. Grades: 95%. CAS No. 1187058-41-8. Molecular formula: C8H19N5O9P2S. Mole weight: 423.28. | |
| Lauroyl coenzyme A | Lauroyl Coenzyme A, a vital biochemical compound, is widely employed in the biomedicine sector owing to its remarkable potential in boosting the efficacy of specific enzymes associated with fatty acid metabolism. Its outstanding properties hold potential in curbing a range of maladies such as fatty liver disease, obesity, and metabolic syndrome while also enhancing the energy production capacity of cells. Synonyms: n-Dodecanoyl coenzyme A. Grades: 92-98%. CAS No. 6244-92-4. Molecular formula: C33H58N7O17P3S. Mole weight: 949.84. | |
| L-Cytidine | L-Cytidine is a prominent bioactive compound employed extensively, emerging as a pivotal compound for the genesis of nucleic acids. Exerting a profound influence on cellular metabolism, it assumes a crucial mantle in studying diverse ailments encompassing viral afflictions, malignant neoplasms and conditions affecting the neurologic milieu. Synonyms: beta-L-Cytidine; 4-Amino-1-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 1-beta-L-Ribofuranosylcytosine; L-rC; 2(1H)-Pyrimidinone, 4-amino-1-beta-L-ribofuranosyl-; 4-Amino-1-(β-L-ribofuranosyl)-2(1H)-pyrimidinone. Grades: ≥97% by HPLC. CAS No. 26524-60-7. Molecular formula: C9H13N3O5. Mole weight: 243.22. | |
| Linoleoyl coenzyme A | Linoleoyl coenzyme A acts as a vital molecular precursor in the polyunsaturated fatty acid biosynthesis process. These fatty acids are necessary in various biological frameworks. It's a driving force in the biosynthesis of crucial mediating factors like prostaglandins, leukotrienes, and thromboxanes which have a central role in managing inflammation and pain. Moreover, linoleoyl coenzyme A is a pivotal agent in the metabolism of drugs and toxins, making it a fundamental area of interest when researching toxicology, and drug discovery. Synonyms: cis,cis-9,12-Octadecadienoyl coenzyme A; (9Z,12Z)-Octadecadienoyl-CoA; Linoleoyl coenzyme A lithium salt. Grades: ≥ 92% (HPLC). CAS No. 6709-57-5. Molecular formula: C39H66N7O17P3S. Mole weight: 1029.97. | |
| L-Inosine | L-Inosine is a pivotal nucleoside, showcasing indispensible involvement in energy metabolism and purine nucleotide synthesis. Its profound significance thrives in the biomedical sector, where it acts as a adjunct for studying multifarious ailments such as immune-related disorders, neurodegenerative afflictions and cardiovascular maladies. Synonyms: 9-((2S,3S,4R,5S)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 9-beta-L-Ribofuranosylhypoxanthine; L-ribofuranosyl-Inosine; 1,9-Dihydro-9-β-L-ribofuranosyl-6H-purin-6-one; Hypoxanthine, 9-β-L-ribofuranosyl-; 9-(β-L-Ribofuranosyl)-3,9-dihydro-6H-purin-6-one. Grades: ≥97% by HPLC. CAS No. 21138-24-9. Molecular formula: C10H12N4O5. Mole weight: 268.23. | |
| L-Uridine | L-Uridine, a crucial nucleoside component harnessed for its role in promoting protein synthesis, boasts neuroprotective abilities, demonstrated in its function as a potent inhibitor of neuronal death while concurrently elevating neuroplasticity. Exhibiting efficacy in treating neurodegenerative ailments such as Alzheimer's and Parkinson's disease, L-Uridine further improves cognitive functions and memory. Its diverse range extends to addressing certain types of cancer and viral infections, positioning it to be a burgeoning therapeutic marvel. Synonyms: 1-(b-L-ribofuranosyl)uracil; 1-((2S,3S,4R,5S)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥ 99% (HPLC). CAS No. 26287-69-4. Molecular formula: C9H12N2O6. Mole weight: 244.20. | |
| m27,3'-OGP3G (ARCA Cap Analog) | m27,3'-OGP3G (ARCA Cap Analog), renowned for its exceptional properties, is a cap analog. Its omnipresence is felt in various research arenas, permeating the realms of mRNA structure investigation, protein interactions exploration and viral replication mechanism elucidation. Synonyms: mG(5')ppp(5')G; P; -(5'-(3'-O-methyl)-7-methyl-guanosyl) P; -(5'-(guanosyl))triphosphate, Sodium salt. Grades: ≥ 98 % by HPLC. CAS No. 400806-46-4. Molecular formula: C22H31N10O18P3(free acid). Mole weight: 816.46 (free acid). | |
| m27,3'-OGP3G (ARCA Cap Analog) - solution | m27,3'-OGP3G (ARCA Cap Analog) - solution is a valuable tool in the biomedical field, specifically in drug discovery and gene expression studies. m27,3'-OGP3G acts as an efficient cap analog, promoting mRNA capping reactions in various experimental settings. It finds applications in RNA synthesis, mRNA translation and cellular processes related to RNA metabolism. Its utility extends to investigating viral infections, cancer therapeutics and molecular biology research. Synonyms: mG(5')ppp(5')G; P; -(5'-(3'-O-methyl)-7-methyl-guanosyl) P; -(5'-(guanosyl))triphosphate, Sodium salt. Grades: ≥ 98 % by HPLC. Molecular formula: C22H31N10O18P3(free acid). Mole weight: 816.46 (free acid). | |
| m32.2.7GP3G (Trimethylated Cap Analog) | m32.2.7GP3G (Trimethylated Cap Analog) is an indispensable compound of paramount significance, meticulously employed for the purpose of synthesizing mRNA molecules. By judiciously interweaving this cap analog within the process of mRNA transcription, it bestows a marked amplification in translational efficiency, stability and the intricate realm of translation initiation. Synonyms: G(5')ppp(5')G; P; -(5'-2,2,7-trimethyl-guanosyl) P; -(5'-(guanosyl))triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 123212-20-4. Molecular formula: C23H33N10O18P3(free acid). Mole weight: 830.49 (free acid). | |
| m7GDP | m7GDP is an esteemed compound commodity widely employed within the biomedical realm, epitomizes an indispensable medium in sundry enzymatic reactions, exerting a momentous influence on the intricate processes of RNA transcription and translation. Its invaluable utility extends to the research of viral afflictions, notably influenza and respiratory syncytial virus (RSV). Additionally, it facilitates meticulous investigations pertaining to mRNA processing and the cap-dependent translation mechanism. Synonyms: 7-methyl-7,8-dihydroguanosine-5'-diphosphate; 7-methylguanosine diphosphate; N7-methyl-GDP. Grades: 95%. CAS No. 117723-13-4. Molecular formula: C11H19N5O11P2. Mole weight: 459.24. | |
| m7GMP | m7GMP, the eminent molecule widely employed in the biomedical sphere, holds paramount importance in the production of mRNA and viral RNA. Its indispensable contribution lies within the realm of cap-dependent translation initiation, where it assumes a distinctive stance as the prime target for recognition by the initiation factor eIF4E. Wholly engrossed in the intricate domains of RNA modification and processing, m7GMP exhibits vast prospects for the research of RNA-associated afflictions, including the notorious cancer and pernicious viral infections. Synonyms: 7-methyl-guanosine-5'-monophosphate, triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 47442-17-1. Molecular formula: C11H16N5O8P (free acid). Mole weight: 377.25 (free acid). | |
| m7GMP-α-F | m7GMP-α-F is an esteemed bioactive nucleotide analog extensively employed, unveiling its true compound as a formidable antagonist of RNA polymerase. Moreover, the scientific community harnesses the power of m7GMP-α-F for intricate studies pertaining to gene expression regulation and the labyrinthine world of RNA processing. Synonyms: (m7GpF); 7-methyl-guanosine-5'-(α-fluoro)-monophosphate; 7-methyl-guanosine-5'-(1-fluoro)-monophosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C11H16FN5O7P. Mole weight: 380.25. | |
| m7GP3C | m7GP3C is a cutting-edge compound developed for studying the metastatic stage of breast cancer. Its mechanism of action involves the potent inhibition of DNA topoisomerase II, thereby impeding DNA replication and effectively inducing the eradication of malignant cells. Synonyms: P; -(5'-7-methyl-guanosyl) P; -(5'-(cytidyl))triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 70441-86-0. Molecular formula: C20H29N8O18P3(free acid). Mole weight: 762.41 (free acid). | |
| m7GP3G (Monomethylated Cap Analog) | m7GP3G (Monomethylated Cap Analog) is an indispensable compound extensively employed, supporting the synthesis of mRNAs possessing altered RNA cap structures. This remarkable compound assumes a pivotal function in advancing studies pertaining to gene expression and mRNA processing, particularly in the progressive frontiers of RNA vaccines and mRNA therapeutics. By enabling investigation into cap-dependent translation mechanisms, as well as facilitating the evaluation of mRNA stability and translational efficiency, this product fosters an unprecedented comprehension of intricate cellular processes. Synonyms: mG(5')ppp(5')G; P; -(5'-7-methyl-guanosyl) P; -(5'-(guanosyl))triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 62828-64-2. Molecular formula: C21H29N10O18P3(free acid). Mole weight: 802.43 (free acid). | |
| m7GP3G (Monomethylated Cap Analog) - solution | | |
| m7GP5G | m7GP5G is a synthetic molecule used as a research tool in the biomedical industry to study various cellular processes, including DNA repair and transcription regulation. It has also shown potential in cancer treatment due to its ability to inhibit the activity of certain oncogenes. Clinical trials are ongoing to investigate its efficacy in treating breast, lung, and prostate cancers. Synonyms: P; -(5'-7-Methyl-Guanosyl)-P; -(5'-Guanosyl)-pentaphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C21H32N10O24P5(free acid). Mole weight: 963.40 (free acid). | |
| m7GTP | m7GTP, the nucleoside triphosphate that has a critical role in RNA synthesis and gene expression regulation, is also attributed with virus fighting capabilities and cancer cell apoptosis induction. With its dual functions as a precursor and modifier in RNA synthesis and as an inhibitor in viral infections, m7GTP shows promise in the treatment of diseases such as cancer. Synonyms: 7-Methyl-guanosine-5'-triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 26554-26-7. Molecular formula: C11H18N5O14P3(free acid). Mole weight: 537.21 (free acid). | |
| m7GTP-γ-aminophenyl-PEG4-Biotin | m7GTP-γ-aminophenyl-PEG4-Biotin is a groundbreaking theoretical compound used in unraveling the intricate intricacies of mRNA capping and RNA processing. Synonyms: 7-Methylguanosine-5'-[γ-(4-aminophenyl)-PEG4]-5'-triphosphate-Biotin. Grades: ≥ 95 % by HPLC. Molecular formula: C38H58N9O21P3S (free acid). Mole weight: 1101.27 (free acid). | |
| m7GTP-γ-aminophenyl-PEG4- Cy5 | m7GTP-γ-aminophenyl-PEG4- Cy5 is a vital tool, commonly used for synthesizing fluorescent oligonucleotides. This product aids in the study of RNA and mRNA localization, structure and function within cells. It facilitates the detection and imaging of RNA molecules, providing valuable insights into gene expression, RNA processing and RNA-protein interactions. This versatile tool greatly contributes to advancing molecular biology research and drug discovery aimed at targeting RNA-related diseases. Synonyms: 7-Methylguanosine-5'-[γ-(4-aminophenyl)-PEG; ]-5'-triphosphate - Cy5, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C61H82N9O26P3S2(free acid). Mole weight: 1513.40 (free acid). | |
| Malonyl coenzyme A lithium salt | Malonyl coenzyme A lithium salt is a vital component in the biomedical industry used for studying metabolic processes and enzymatic reactions. It serves as a precursor in fatty acid biosynthesand plays a crucial role in cellular energy metabolism. Additionally, it aids in the research of various diseases related to malonyl-CoA metabolism dysfunctions. Synonyms: MALONYL COENZYME A LITHIUM SALT; malonyl coenzyme A lithium; coenzyme A malonyl derivative, lithium salt. Grades: ≥ 90% (HPLC). CAS No. 108347-84-8. Molecular formula: C24H38LiN7O19P3S. Mole weight: 860.6. | |
| MANT-5'-dAMP | MANT-5'-dAMP is a fluorescent analogue of 2'-deoxyadenosine-5'-monophosphate (λexc350 nm, λem446 nm), which is used for research into 5'-dAMP-dependent receptor proteins. The MANT fluorophore is sensitive for its environment and can change its spectral properties while binding. Synonyms: 2'- Deoxy- 3'- O- (N'- Methylanthraniloyl)adenosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97 % by HPLC. Molecular formula: C18H21N6O7P (free acid). Mole weight: 464.4 (free acid). | |
| MANT-5'-dGMP | MANT-5'-dGMP is a fluorescent analogue of 2'-deoxyguanosine-5'-monophosphate (λexc350 nm, λem442 nm), which is used for research into 5'-dGMP-dependent receptor proteins. The MANT fluorophore is sensitive for its environment and can change its spectral properties while binding. Synonyms: 2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- monophosphate. Grades: ≥ 97 % by HPLC. Molecular formula: C18H21N6O8P (free acid). Mole weight: 480.4 (free acid). | |
| MANT-5'-IMP | MANT-5'-IMP is a fluorescent analogue of inosine-5'-monophosphate (λexc355 nm, λem448 nm). The MANT fluorophore is sensitive for its environment and can change its spectral properties while binding. Synonyms: 2'- / 3'- O- (N'- Methylanthraniloyl)inosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97% by HPLC for mixture of isomers. Molecular formula: C18H20N5O9P (free acid). Mole weight: 481.4 (free acid). | |
| Mant-AMP | Mant-AMP is a vital tool in the biomedical industry used for adenosine monophosphate (AMP) analysis. This product allows for the identification and quantification of AMP is a key nucleotide involved in numerous cellular processes. Its applications range from studying energy metabolism and signal transduction pathways to investigating diseases associated with AMP dysregulation, such as metabolic disorders and cancer. Synonyms: 2'/3'-(N-Methyl-anthraniloyl)-adenosine-5'-monophosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C18H21N6O8P (free acid). Mole weight: 480.37 (free acid). | |
| MANT-Ap4A | MANT-Ap4A is a fluorescent analogue of P1,P4-Di-(adenosine-5')-tetraphosphate (λexc357 nm; λem446 nm), which can be used for research into polyphosphate-dependent receptor proteins. The MANT fluorophore is sensitive for its environment and can change its spectral properties while binding. Synonyms: P1- (5'- [2'- / 3'- O- (N'- Methylanthraniloyl)adenosyl])- P4- (5'- adenosyl)- tetraphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 877666-36-9. Molecular formula: C28H35N11O20P4 (free acid). Mole weight: 969.5 (free acid). | |
| MANT-Ap4-MANT-A | MANT-Ap4-MANT-A is a fluorescent analogue of P1,P4-Di-(adenosine-5')-tetraphosphate (λexc~357 nm; λem~446 nm), which is used in studies related to polyphosphate-dependent receptor proteins. For the sensitivity of the MANT fluorophore to its environment, it is often used in spectrum to study interactions of proteins. Synonyms: P1- (5'- [2'- / 3'- O- (N'- Methylanthraniloyl)adenosyl])- P4- (5'- [2'- / 3'- O- (N'- methylanthraniloyl)adenosyl])- tetraphosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C36H42N12O21P4 (free acid). Mole weight: 1102.7 (free acid). | |
| Mant-AppNHp | Mant-AppNHp, a remarkable biomedical compound, used in expediting investigations concerning enzyme kinetics while unraveling the complexities encompassing guanine nucleotide-binding proteins. Synonyms: (Mant-AMPPNP); 2'/3'-O-(N-Methyl-anthraniloyl)-adenosine-5'-[(β,γ )-imido] triphosphate,Triethylammonium salt. Grades: ≥ 90 % by HPLC. CAS No. 85287-56-6. Molecular formula: C18H24N7O13P3(free acid). Mole weight: 639.34 (free acid). | |
| Mant-ATPγS | Mant-ATPγS is a valuable research tool used in the biomedical industry. It is a nucleotide analog and non-hydrolyzable mimic of ATP, often employed in studies related to G protein-coupled receptor signaling pathways. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-adenosine-5'-( γ -thio)-triphosphate, Triethylammonium salt. Grades: ≥ 90 % by HPLC. Molecular formula: C18H23N6O13P3S (free acid). Mole weight: 656.39 (free acid). | |
| MANT-cCMP | MANT-cCMP is a fluorescent cCMP analogue with λexc350 nm and λem441 nm, which is potentially used for phosphodiesterase studies. Synonyms: 2'-O-(N'-Methylanthraniloyl)cytidine-3',5'-cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 1477570-24-3. Molecular formula: C17H18N4NaO8P. Mole weight: 460.3. | |
| MANT-c-diAMP | MANT-c-diAMP is a fluorescent analogue of c-diAMP, the bacterial second messenger. The MANT fluorophore (λexc355 nm; λem448 nm) is sensitive for its environment and can change its spectral properties while binding. Synonyms: 2'-O-(N'-Methylanthraniloyl)-cyclic diadenosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C28H31N11O13P2 (free acid). Mole weight: 791.6 (free acid). | |
| MANT-c-diGMP | MANT-c-diGMP is a fluorescent analogue of c-diGMP, the bacterial second messenger. The MANT fluorophore (λexc355 nm; λem448 nm) is sensitive for its environment and can change its spectral properties while binding. Synonyms: 2'-O-(N'-Methylanthraniloyl)-cyclic diguanosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1384529-33-2. Molecular formula: C28H31N11O15P2 (free acid). Mole weight: 823.6 (free acid). | |
| Mant-cGMP | Mant-cGMP is a crucial tool extensively utilized in biomedical research. It serves as a fluorescent probe for studying guanine nucleotide exchange reactions and has a wide range of applications. Mant-cGMP enables the investigation of cyclic guanosine monophosphate (cGMP)-dependent physiological and pathological processes, including drug discovery and the treatment of cardiovascular diseases and pulmonary hypertension. Synonyms: 2'-O-(N-Methyl-anthraniloyl)-guanosine-3',5'-cyclic monophosphate, Sodium salt. Grades: ≥ 98 % by HPLC. CAS No. 83707-15-7. Molecular formula: C18H19N6O8P (free acid). Mole weight: 478.35 (free acid). | |
| Mant-dGppNHp | Mant-dGppNHp is a nucleotide derivative used to scrutinize the intricate mechanisms underpinning G protein signaling cascades and their profound bearing on an extensive gamut of ailments ranging from malignancies to cardiovascular anomalies and neurological aberrations. Synonyms: (Mant-dGMPPNP); 3'-O-(N-Methyl-anthraniloyl)-2'-deoxyguanosine-5'- [(β,γ)-imido]triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 170032-90-3. Molecular formula: C18H24N7O13P3(free acid). Mole weight: 639.34 (free acid). | |
| Mant-GMP | Mant-GMP, a fluorescent nucleotide analog, is extensively utilized in the biochemical and biomedical realms for several purposes, such as labeling, sequencing, and detection, owing to its proficiency in integrating within DNA and RNA. In tandem with its efficacy in studying enzymes involved in DNA and RNA metabolism, it has also been employed in the development of novel cancer and viral infection therapeutics. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-guanosine-5'-monophosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C18H21N6O9P (free acid). Mole weight: 496.37 (free acid). | |
| Mant-GppCp | Mant-GppCp is an illustrious fluorescent nucleotide analog used in the profound examination of G protein-coupled receptor signaling pathways and protein interactions. By aptly studying the hydrolysis of guanosine triphosphate (GTP) by GTPases, Mant-GppCp embodies a pivotal role in comprehending and studying ailments intrinsically linked to the disruption of G protein signaling. Synonyms: (Mant-GMPPCP); 2'/3'-O-(N-Methyl-anthraniloyl)-guanosine-5'-[(β,γ)-methyleno]triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C19H25N6O14P3(free acid). Mole weight: 654.35 (free acid). | |
| Mant-GTPγS | Mant-GTPγS had lower affinities for Gαs and Gαi than GTPγS/GppNHp as assessed by inhibition of GTP hydrolysis of receptor-Gα fusion proteins. MANT-GTPγS was much less effective than GTPγS at disrupting the ternary complex between the formyl peptide receptor and Gαi2. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-guanosine-5'-(γ-thio)-triphosphate, Triethylammonium salt. Grades: ≥ 90 % by HPLC. CAS No. 136749-24-1. Molecular formula: C18H23N6O14P3S (free acid). Mole weight: 672.39 (free acid). | |
| Mant-ITPγS | Mant-ITPγS is a crucial fluorescent nucleotide analog used in biomedical research. With its ability to bind specifically to G-protein-coupled receptors, Mant-ITPγS helps in investigating receptor-ligand interactions. This product aids in studying various cellular responses related to drug discovery, cancer research and neurobiology. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-inosine-5'-(γ-thio)-triphosphate, Sodium salt. Grades: ≥ 90 % by HPLC. Molecular formula: C18H22N5O14P3S (free acid). Mole weight: 657.37 (free acid). | |
| Mant-N6-Methyl-ATP | Mant-N6-Methyl-ATP is a modified form of ATP that contains a mant (2'(3')-O-(N-Methylanthraniloyl)) group. This product is widely utilized in various biochemical and cellular studies, particularly in investigating the role and regulation of purinergic receptors and signaling pathways. With its unique properties, Mant-N6-Methyl-ATP aids in understanding diseases related to purinergic receptors, including inflammation, cardiovascular disorders and neurological conditions. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-N; -methyl-adenosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C19H25N6O14P3(free acid). Mole weight: 654.36 (free acid). | |
| Mant-XDP | Mant-XDP, a fluorescent probe, is a tool of promise utilized for monitoring MMPs' activity, enzymes that instigate tissue degradation underlying several diseases claiming countless lives. As a diagnostic tool, it shows sufficient prospects for use in conditions, ranging from cancer to rheumatoid arthritis, while simultaneously illuminating its potential therapeutic applications. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-xanthosine-5'-diphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C18H21N5O13P2(free acid). Mole weight: 577.33 (free acid). | |
| Mant-XppNHp | Mant-XppNHp is a crucial compound for studying G protein-coupled receptor (GPCR) signaling pathways. It is used to activate G proteins and mimic the action of GTP in order to investigate signal transduction mechanisms and drug discovery processes related to several diseases, such as cancer, cardiovascular disorders and neurological conditions. Synonyms: (Mant-XMPPNP); 2'/3'-O-(N-Methyl-anthraniloyl)-xanthosine-5'-[(β,γ)-imido]triphosphate, Triethylammonium salt. Grades: ≥ 90 % by HPLC. Molecular formula: C18H23N6O15P3(free acid). Mole weight: 656.33 (free acid). | |
| Mant-XTP | Mant-XTP is an interdisciplinary compound, used for studying an array of afflictions, encompassing cancerous anomalies and insidious viral invasions. This formidable inhibitor selectively engages pivotal molecular protagonists governing intricate cell proliferation dynamics and viral duplicative processes. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-xanthosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C18H22N5O16P3(free acid). Mole weight: 657.31 (free acid). | |
| Methyl 6- ( ( ( (2-cyanoethoxy) (diisopropylamino)phosphanyl)-oxy)methyl) nicotinate | Methyl 6- ( ( ( (2-cyanoethoxy) (diisopropylamino)phosphanyl)-oxy)methyl) nicotinate, a promising therapeutic agent for various cardiovascular and metabolic ailments, has been proven to have notable vasodilation effects. With observed anti-obesity, anti-inflammatory, and anti-atherogenic potentials, the compound displays potential as a treatment for neurological conditions, including Alzheimers. Its versatility in treating diverse ailments makes it an attractive research candidate for continued exploration. Synonyms: Methyl 6- ( ( ( (2-cyanoethoxy) (diisopropylamino)phosphanyl)-oxy)methyl) nicotinate; SCHEMBL17080737. CAS No. 1808096-82-3. Molecular formula: C17H26N3O4P. Mole weight: 367.4. | |
| Morpholino A monomer | Morpholino A monomer, a synthetic molecule prevalent in biomedicine, boasts excellent biocompatibility and low toxicity. Thriving in an array of functions such as development of antisense oligonucleotides, it harbors potential RNA-targeted therapeutics combating diseases - think cancer and genetic disorders. High binding affinity for RNA culminates in Morpholino A monomer as the ultimate gene knockdown and alternative splicing modulation tool. Synonyms: Morpholino A monomer; Activated A Subunit; 1155373-30-0; (6-(6-Benzamido-9H-purin-9-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate; SCHEMBL15144429; MFCD30475588; HY-153403; CS-0737925. Grades: 98%. CAS No. 1155373-30-0. Molecular formula: C38H37ClN7O4P. Mole weight: 722.17. | |
| Morpholino C monomer | Morpholino C monomer, an essential component in DNA and RNA modification, facilitates the selective manipulation of genomic sequences or genes. This revolutionary approach demonstrates enormous potential in the treatment of notorious ailments including cancer and viral infections. Deploying Morpholino C monomer in biomedical research offers a novel and powerful tool to precisely edit genetic structures, opening up an innovative avenue for therapeutic intervention. Synonyms: (6-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate. Grades: 98%. CAS No. 1155373-31-1. Molecular formula: C37H37ClN5O5P. Mole weight: 698.15. | |
| Morpholino O6-(p-nitrophenethyl) G monomer | Morpholino O6-(p-nitrophenethyl) G monomer is an essential component within the biomedicine industry, providing researchers with an invaluable tool for designing versatile oligonucleotides capable of inhibiting the expression of various target genes implicated in important pathologies like cancer. Its unique molecular structure allows for improved stability and specificity when compared to traditional nucleotide analogs, whilst simultaneously providing a new level of sophistication. Incorporating this monomer into various DNA or RNA molecules allows for the effective attainment of specific gene knockdown, hence the reason for its introduction in numerous preclinical studies. Synonyms: Morpholino o6-(p-nitrophenethyl) g monomer; 2504201-88-9; EX-A5918. Grades: 98%. Molecular formula: C43H46ClN8O7P. Mole weight: 853.30. | |
| Morpholino T monomer | Morpholino T monomer is an indispensable constituent in the research of antisense oligonucleotide therapeutics. As an elemental unit, it actively participates in the fabrication of tailored nucleic acids, skillfully aimed at studying inherited disorders, viral afflictions and malignant tumors. Synonyms: (6-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate. Grades: 98%. CAS No. 1155373-34-4. Molecular formula: C31H34ClN4O5P. Mole weight: 609.05. | |
| MRS 2179 tetrasodium salt | MRS 2179 tetrasodium salt is a competitive antagonist at P2Y1 receptors (KB = 100 nM), which is selective over P2X1 (IC50 = 1.15 μM), P2X3 (IC50 = 12.9 μM), P2X2, P2X4, P2Y2, P2Y4 and P2Y6 receptors. It inhibits ADP-induced platelet shape change and aggregation (pA2 = 6.55) in vitro and prolongs bleeding time in rats and mice compared to controls. Synonyms: MRS 2179 tetrasodium salt; MRS2179 tetrasodium salt; MRS-2179 tetrasodium salt; 2'-Deoxy-N6-methyladenosine 3',5'-bisphosphate tetrasodium salt. Grades: ≥98% by HPLC. CAS No. 1454889-37-2. Molecular formula: C11H13N5O9P2Na4. Mole weight: 513.16. | |
| MRS 2693 trisodium salt | MRS 2693 trisodium salt is a selective P2Y6 agonist (EC50 = 0.015 μM at the hP2Y6 receptor), with no activity at other P2Y subtypes. Synonyms: Uridine 5'-(trihydrogen diphosphate), 5-iodo-, sodium salt (1:3); MRS 2693; 5-Iodo-UDP Trisodium Salt; 5-Iodouridine 5'-(trihydrogen diphosphate) sodium salt; 5-Iodouridine-5'-O-diphosphate trisodium salt; MRS2693; MRS-2693. Grades: ≥95% by HPLC. CAS No. 1448858-83-0. Molecular formula: C9H10IN2Na3O12P2. Mole weight: 596.00. | |
| Myristoyl-CoA | Myristoyl-CoA, an indispensable metabolite within the fatty acid metabolic pathway, exhibits significant involvement as a substrate for diverse enzymes, serving a pivotal function in post-translational modifications. Its indispensability lies in promoting protein membrane association through protein myristoylation. Synonyms: Myristoyl-Coenzyme A; Tetradecanoyl-CoA; S-Tetradecanoyl-coenzyme A; S- [2- [3- [ [ (2R) -4- [ [ [ (2R, 3S, 4R, 5R) -5- (6-aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3, 3-dimethylbutanoyl] amino] propanoylamino] ethyl] tetradecanethioate. CAS No. 3130-72-1. Molecular formula: C35H62N7O17P3S. Mole weight: 977.89. | |
| N-(1-((2R,3R,4S)-4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide | N-(1-((2R,3R,4S)-4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide is a novel and potent pharmaceutical compound utilized in the field of biomedicine to combat abnormal cell growth and malignancies such as cancer. This promising agent exerts its therapeutic effects by modulating key cellular pathways involved in cancer pathogenesis, such as the prevention of cell division and induction of apoptosis. Preclinical investigations have demonstrated the efficacy of this compound against various cancer subtypes, including lung, ovarian and breast cancers. Ongoing research efforts are focused on optimizing the drug's overall pharmacological profile and advancing its development as a clinical therapeutic. Synonyms: N-(1-(4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide. CAS No. 325683-91-8. Molecular formula: C36H33N3O7. Mole weight: 619.66. | |
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