BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 1-(5-(Difluoromethoxy)-1H-benzo[d]imidazol-2-yl)-3-methoxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid | An impurity of Pantoprazole, which is a prescription drug used as a short-term treatment for gastroesophageal reflux disease (GERD). Synonyms: Pantoprazole Impurity 51; 1-[6-(Difluoromethoxy)-1H-benzimidazol-2-yl]-1,4-dihydro-3-methoxy-4-oxo-2-pyridinecarboxylic acid. Grade: ≥95%. CAS No. 2512209-15-1. Molecular formula: C15H11F2N3O5. Mole weight: 351.26. |  |
| 1,5-Di-O-acetyl-2,3-O-isopropylidene-D-ribofuranose | 1,5-Di-O-acetyl-2,3-O-isopropylidene-D-ribofuranose is a biological reagent playing a role in synthesizing various nucleotide and nucleoside analogs. CAS No. 141979-56-8. Molecular formula: C12H18O7. Mole weight: 274.27. | |
| 1-[(5E)-3-O-[(Bis-di-isopropylamino)(2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]-5-methyluracil | 1-[(5E)-3-O-[(Bis-di-isopropylamino)(2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]-5-methyluracil is an exceptionally powerful antiviral therapy that has shown remarkable promise in fighting HIV-1 and other retroviral infections. With its distinctive molecular structure and inhibitive function against the viral genetic makeup, this drug has the potential to pave the way for a new generation of antiviral treatments. Clinical trials have proven its efficacy, highlighting its vital role in the treatment of conditions previously thought incurable. The uniqueness of this product lies in its complexity its scientific brilliance lies in its simplicity. Experience the power of science with 1-[(5E)-3-O-[(Bis-di-isopropylamino)(2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]-5-methyluracil. Synonyms: 3-[[(2R,3R,4R,5R)-2-[(E)-2-diethoxyphosphorylethenyl]-4-(2-methoxyethoxy)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile. Grade: ≥95%. CAS No. 1345562-47-1. Molecular formula: C27H46N4O10P2. Mole weight: 648.62. | |
| 1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]uracil | 1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]uracil - a remarkable pharmaceutical compound known for its potency against viral infections. Deemed an anti-DNA virus agent, this unique product is effective against formidable pathogens like herpes simplex virus (HSV), varicella-zoster virus (VZV), and even the notorious human immunodeficiency virus (HIV). By restraining viral DNA polymerase, it deftly curtails virus replication, ultimately conferring unparalleled therapeutic benefits. Grade: ≥95%. Molecular formula: C26H44N4O10P2. Mole weight: 634.60. | |
| 1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy)phos-phino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]uracil | 1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy)phos-phino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]uracil, a potent agent for the treatment of human immunodeficiency virus (HIV) infections, functions as a viral replication inhibitor by suppressing the reverse transcriptase enzyme. Its intricate molecular structure reflects the sophisticated nature of modern pharmaceuticals, which require cutting-edge research and development to ultimately undo the feats of viruses and other elusive adversaries. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[(5E)-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]-. Grade: ≥95%. CAS No. 2361324-80-1. Molecular formula: C24H40N4O9P2. Mole weight: 590.54. | |
| 1-[(5E)-5',6'-Dideoxy-6'-diethoxylphosphinyl-2'-O-methyl-b-D-ribo-hex-5-enofuranosyl]uracil 3'-CE phosphoroamidite | 1-[(5E)-5',6'-Dideoxy-6'-diethoxylphosphinyl-2'-O-methyl-b-D-ribo-hex-5-enofuranosyl]uracil 3'-CE phosphoroamidite, an indispensable compound in the biomedical field, assumes a noteworthy position. This derivative of phosphoroamidite assumes a pivotal role in the synthesis of modified oligonucleotides, a critical pursuit in both research and therapeutic contexts. Its distinctive structure empowers the integration of altered nucleosides into DNA or RNA strands, bolstering their stability and advancing their therapeutic potential. Grade: 95%. Molecular formula: C22H36N4O9P2. Mole weight: 562.49. | |
| 1-[(5E)-5,6-Dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]uracil | The nucleoside analogue, 1-[(5E)-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]uracil, is a potent antiviral weapon against both HIV and hepatitis B. By inhibiting viral reverse transcriptase, it has the power to eliminate viral replication and halt spreading within the body. Its effectiveness is further amplified when used in tandem with other antiretroviral drugs, which substantially reduces the risk of drug resistance. Grade: ≥95%. Molecular formula: C17H27N2O9P. Mole weight: 434.38. | |
| 1-[(5E)-5,6-Dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-b-D-ribo-hex-5-enofuranosyl]uracil | 1-[(5E)-5,6-Dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-b-D-ribo-hex-5-enofuranosyl]uracil, an immensely powerful antiviral compound, finds its application in the management of viral infections. It exhibits remarkable efficacy in selectively impeding RNA virus replication by perturbing their genetic material. Its utility extends to combatting ailments caused by RNA viruses, such as influenza, hepatitis C, and respiratory syncytial virus. This prodigious molecule, with its distinctive molecular architecture and mode of action, assumes invaluable importance within the realm of biomedical science, offering unprecedented prospects in combating detrimental viral pathogens. | |
| 1-[(5E)-5,6-Dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]uracil | 1-[(5E)-5,6-Dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]uracil, an extraordinary biomedicine, manifests its potential as a breakthrough antiviral agent. By adeptly targeting the viral uracil-DNA glycosylase enzyme, it inhibits viral replication and hinders viral DNA synthesis. Its molecular architecture, distinctive and resolute, engenders unrivaled selectivity and efficacy across diverse viral strains. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[(5E)-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]-; 1-[(2R,3R,4R,5R)-5-[(E)-2-diethoxyphosphorylethenyl]-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione. Grade: ≥95%. CAS No. 2095417-05-1. Molecular formula: C15H23N2O8P. Mole weight: 390.33. | |
| 1-[(5E)-5,6-Dideoxy-6-phosphono-2-O-methyl-β-D-ribo-hex-5-enofuranosyl)uracil | 1-[(5E)-5,6-Dideoxy-6-phosphono-2-O-methyl-β-D-ribo-hex-5-enofuranosyl)uracil, an inhibitor derived amidst nucleoside analogues, is widely employed to counteract hepatitis B virus contagion, reflecting its potential to quash the reverse transcriptase enzyme's functionality, ultimately mitigating the virus's replication ability and, in turn, reducing the viral load in the body. Its efficacy, when combined with other antiviral drugs, exponentially augments its curative prowess, making it the go-to option for preemptive treatment of prolonged hepatitis B. Grade: ≥95%. CAS No. 2095417-50-6. Molecular formula: C11H15N2O8P. Mole weight: 334.22. | |
| 15-epi Bimatoprost | 15-epi Bimatoprost is an intermediate in the production of Bimatoprost. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenamide; (15R)-Bimatoprost. Grade: > 95%. CAS No. 1163135-92-9. Molecular formula: C25H37NO4. Mole weight: 415.58. | |
| 15-epi-Travoprost | One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester. CAS No. 1420791-14-5. Molecular formula: C26H35F3O6. Mole weight: 500.56. | |
| 15-epi-Travoprost Epoxide | One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Molecular formula: C26H35F3O7. Mole weight: 516.56. | |
| 15-Hydroxofeudomycin B | 15-Hydroxofeudomycin B is an impurity of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-9-(3-hydroxy-2-oxopropyl)-8,10-dihydro-7H-tetracene-5,12-dione. Molecular formula: C28H31NO11. Mole weight: 557.55. | |
| 15-Hydroxy Lubiprostone | 15-Hydroxy Lubiprostone is a synthetic derivative of prostaglandin E1 used in the biomedical industry. It acts as a local intestinal chloride channel activator and is employed in the research of chronic idiopathic constipation and irritable bowel syndrome with constipation. Synonyms: 9-oxo-11α,15S-dihydroxy-16,16-difluoro-prostan-1-oic acid. Grade: > 95%. CAS No. 475992-30-4. Molecular formula: C20H34F2O5. Mole weight: 392.5. | |
| 15-Hydroxy lubiprostone-d4 | 15-Hydroxy lubiprostone-d4 is a labelled impurity of lubiprostone. Lubiprostone is a medication indicated for the treatment of certain types of constipation. Synonyms: 7-[2-(4,4-difluoro-3-hydroxyoctyl)-3-hydroxy-5- oxocyclopentyl](2,2,4,4-D4)heptanoic acid. Grade: > 95%. Molecular formula: C20H30F2O5D4. Mole weight: 396.51. | |
| 1,5-Isoquinolinediol | 1,5-Isoquinolinediol is a PARP1 inhibitor (IC50 value 0.39 - 1.00 μM) and neuroprotective agent leading to an increase up to 8-fold in the absolute frequency of gene targeting in the correction of the mutation at the stable integrated HSV tk gene in mouse Ltk cells. 1,5-Isoquinolinediol is also an inducible nitric oxide synthase (NOS2) inhibitor. 1,5-Isoquinolinediol significantly inhibited mitochondrial membrane potential loss, AIF (apoptosis inducing factor) and cytochrome c release from the mitochondria. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: 1,5-Dihydroxyisoquinoline; Isoquinoline-1,5-diol; 5-Hydroxy-1(2H)-isoquinolinone; 5-Hydroxyisocarbostyril. Grade: 99%. CAS No. 5154-2-9. Molecular formula: C9H7NO2. Mole weight: 161.16. | |
| 15-keto-17-phenyl trinor prostaglandin F2α | 15-keto-17-phenyl-13,14-dihydro trinor PGF2α isopropyl ester is a miotic in the normal cat eye, causing an 8 mm reduction in pupillary diameter at 5 μg/eye. Synonyms: 15-keto-17-phenyl trinor PGF2α; (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxo-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid. Grade: ≥98%. CAS No. 949564-89-0. Molecular formula: C23H30O5. Mole weight: 386.5. | |
| 15-Keto Bimatoprost | 15-Keto Bimatoprost is an impurity of Bimatoprost. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E)-3-oxo-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenamide; Bimatoprost Impurity III. Grade: > 95%. CAS No. 1163135-96-3. Molecular formula: C25H35NO4. Mole weight: 413.56. | |
| 15-Keto Latanoprost | a metabolite of Latanoprost. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; [1R-[1α(Z),2β,3α,5α]]-7-[3,5-Dihydroxy-2-(3-oxo- 5-phenylpentyl)cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester. Grade: > 95%. CAS No. 135646-98-9. Molecular formula: C26H38O5. Mole weight: 430.59. | |
| 15-Keto Latanoprost Acid | a potential metabolite of latanoprost when administered to animals. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-5-heptenoic Acid. Grade: > 95%. CAS No. 369585-22-8. Molecular formula: C23H32O5. Mole weight: 388.51. | |
| 15-keto Limaprost | an impurity of Limaprost. Synonyms: (2E,11α,13E,17S)-11-Hydroxy-17,20-dimethyl-9,15-dioxoprosta-2,13-dien-1-oic Acid. Grade: > 95%. Molecular formula: C22H34O5. Mole weight: 378.51. | |
| 15-Keto Prostaglandin E1 | An impurities of Prostaglandin E1. Prostaglandin E1 is a naturally occurring prostaglandin. It is used to treat erectile dysfunction. Synonyms: (11α,13E)-11-Hydroxy-9,15-dioxo-prost-13-en-1-oic Acid; 3-Hydroxy-5-oxo-2-(3-oxo-1-octenyl)-cyclopentaneheptanoic Acid; 15-Keto-PGE1; 15-Oxo-PGE1; 15-Oxoprostaglandin E1; U 22409. Grade: > 95%. CAS No. 22973-19-9. Molecular formula: C20H32O5. Mole weight: 352.48. | |
| 15-Keto prostaglandin E2 | 15-Keto prostaglandin E2 is a metabolite of PGE2 formed by 15-hydroxy PGDH. Synonyms: 15-keto PGE2; 15-Oxo-PGE2. Grade: ≥95%. CAS No. 26441-05-4. Molecular formula: C20H30O5. Mole weight: 350.5. | |
| 15-Keto Travoprost | One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; 15-keto Fluprostenol Isopropyl Ester. CAS No. 404830-45-1. Molecular formula: C26H33F3O6. Mole weight: 498.54. | |
| 15-Lipoxygenase Inhibitor 1 | 15-Lipoxygenases (15-LO) inhibitor 1 is a heterocyclic pyrimidobenzothiazine compound that inhibits 15-LO with an IC50 value of 18 μM. Synonyms: 15-LO Inhibitor 1; 4-methyl-2-(4-methylpiperazin-1-yl)-5H-pyrimido[4,5-b][1,4]benzothiazine. Grade: ≥95%. CAS No. 928853-86-5. Molecular formula: C16H19N5S. Mole weight: 313.4. | |
| 15-LOX-1 inhibitor i472 | 15-LOX-1 inhibitor i472 is an inhibitor of 15-lipoxygenase-1 (15-LOX-1) with an IC50 value of 0.19 μM. In vitro, 15-LOX-1 inhibitor i472 protected cells from lipopolysaccharide-induced cell death, inhibiting NO formation and lipid peroxidation. Synonyms: (E)-Ethyl 6-chloro-3-(3-(2-methoxybenzylamino)-3-oxoprop-1-enyl)-1H-indole-2-carboxylate; 6-Chloro-3-[(1E)-3-[[(2-methoxyphenyl)methyl]amino]-3-oxo-1-propen-1-yl]-1H-indole-2-carboxylic acid, ethyl ester. Grade: 98%. CAS No. 2349374-37-2. Molecular formula: C22H21ClN2O4. Mole weight: 412.87. | |
| 1,5-methano-1H-3-benzazepine | 1,5-methano-1H-3-benzazepine is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It is a prescription drug used to treat cigarette addiction. Synonyms: 1-(7,8-dinitro-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one; 2,3,4,5-Tetrahydro-7,8-dinitro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine; 1-(4,5-dinitro-10-aza-tricyclo[6.3.1.0(2,7)]dodeca-2(7),3,5-triene-10-yl)-2,2,2-trifluoro-ethanone; 2,2,2-Trifluoro-1-(1,2,4,5-tetrahydro-7,8-dinitro-1,5-methano-3H-3-benzazepin-3-yl)ethanone. Grade: ≥ 95%. CAS No. 230615-59-5. Molecular formula: C13H10F3N3O5. Mole weight: 345.23. | |
| 1-[(5-Methylisoxazol-3-yl)methyl]piperazine | 1-[(5-Methylisoxazol-3-yl)methyl]piperazine is a P2Y12 inhibitor. Synonyms: 1-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazine. CAS No. 173850-51-6. Molecular formula: C9H15N3O. Mole weight: 181.23. | |
| 15-Methyl PGE2 methyl ester | 15-Methyl PGE2 methyl ester. Synonyms: Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-15-methyl-9-oxo-, methyl ester, (5Z,11α,13E,15S)-; (15S)-15-Methyl PGE2 methyl ester; (15S)-15-Methylprostaglandin E2 methyl ester; 15(S)-15-Methyl-PGE2 methyl ester; 15(S)-Methyl-PGE2 methyl ester; 15(S)-Methylprostaglandin E2 methyl ester; 15-Methylprostaglandin E2 methyl ester. CAS No. 36210-00-1. Molecular formula: C22H36O5. Mole weight: 380.52. | |
| 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-deoxy-β-D-threo-pentofuranosyl]-2,4(1H,3H)-pyrimidinedione | 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-deoxy-β-D-threo-pentofuranosyl]-2,4(1H,3H)-pyrimidinedione is a vital compound extensively utilized in the field of biomedicine. This product acts as a key reagent in the synthesis of modified nucleotides for research purposes. It is commonly employed in DNA and RNA synthesis, particularly in the development of oligonucleotides for therapeutic interventions targeting various diseases, such as cancer and viral infections. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-deoxy-β-D-threo-pentofuranosyl]-; 5-O-(4,4'-Dimethoxytrityl)-2-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1,3-dideoxy-1-uracil-1-yl-beta-D-threo-pentofuranose; (2R,3S,5S)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 3'-ara-dU Phosphoramidite; 5'-O-DMTr-3'-deoxyuridine ara-2'-phosphoramidite. Grade: ≥95%. CAS No. 161503-98-6. Molecular formula: C39H47N4O8P. Mole weight: 730.79. | |
| 1-(5-O-(Dimethoxytrityl)-β-D-2-deoxyribofuranosyl)-3-nitropyrrole | 1-(5-O-(Dimethoxytrityl)-β-D-2-deoxyribofuranosyl)-3-nitropyrrole is a biochemical utilized in synthesizing oligonucleotides. This chemical compound essentially aids drugs used in genetic research and in treating genetic diseases with gene therapy. Synonyms: 1-(5-O-(DIMETHOXYTRITYL)-BETA-D-2-DEOXYRIBOFURANOSYL)-3-NITROPYRROLE; (2R,3S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(3-nitropyrrol-1-yl)oxolan-3-ol; (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(3-nitro-1H-pyrrol-1-yl)tetrahydrofuran-3-ol; 1H-Pyrrole,1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-b-D-erythro-pentofuranosyl]-3-nitro-. Grade: ≥ 95%. CAS No. 166984-63-0. Molecular formula: C30H30N2O7. Mole weight: 530.58. | |
| 1-(5-O-(Dimethoxytrityl)-β-D-2-deoxyribofuranosyl)-4-methylindole | 1-(5-O-(Dimethoxytrityl)-β-D-2-deoxyribofuranosyl)-4-methylindole is a nucleoside mimic. Its paramount function involves participating in the construction of antiviral pharmacological substances, thus potentially reinforcing the potency against pathological conditions borne from viral incursions. Grade: ≥ 97%. CAS No. 180737-32-0. Molecular formula: C35H35NO5. Mole weight: 549.68. | |
| 1-(5-O-(Dimethoxytrityl)-β-D-2-deoxyribofuranosyl)-5-nitroindole | 1-(5-O-(Dimethoxytrityl)-β-D-2-deoxyribofuranosyl)-5-nitroindole is an integral element in the synthesis of oligonucleotides, manifesting its criticality in genetic research endeavours, specifically for ameliorating genetic afflictions. This compound's significance is pronounced in the constitution of antisense drugs that target selective DNA or RNA sequences. Synonyms: 1-(5-O-(DIMETHOXYTRITYL)-beta-D-2-DEOXYRIBOFURANOSYL)-5-NITROINDOLE; (2R,3S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(5-nitroindol-1-yl)oxolan-3-ol; 1-(5'-O-DMT-b-D-2-deoxyribofuranosyl)-5-nitroindole; (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-nitro-1H-indol-1-yl)tetrahydrofuran-3-ol. Grade: ≥ 97%. CAS No. 869355-18-0. Molecular formula: C34H32N2O7. Mole weight: 580.63. | |
| 1-(5'-O-DMT-b-D-xylofuranosyl)thymine | 1-(5'-O-DMT-b-D-xylofuranosyl)thymine, a highly potent antiviral agent extensively employed in biomedical studies, warrants utmost caution. Renowned for its commendable efficacy against formidable viral adversaries like HIV and hepatitis B, this product symbolizes hope in the realms of therapeutic interventions. Through its remarkable ability to impede viral DNA replication and synthesis, it emerges as an indispensable instrument in unraveling the intricacies of antiviral remedies, augmenting our understanding of these maladies. | |
| 1-(5-O-Methoxytrityl-2-deoxy-b-D-xylofuranosyl)uracil | 1-(5-O-Methoxytrityl-2-deoxy-b-D-xylofuranosyl)uracil is an indispensable element in oligonucleotide synthesis. It can be used to catalyze the formulation of potent antiviral drugs aimed at diseases such as Hepatitis and HIV. Synonyms: 1-[(2S,4R,5R)-4-hydroxy-5-[[(4-methoxyphenyl)-diphenylmethoxy]methyl]oxolan-2-yl]pyrimidine-2,4-dione; 2'-Deoxy-5'-O-MMT-uridine; 5'-O-MMT-2'-deoxyuridine. Grade: ≥95%. CAS No. 2072145-82-3. Molecular formula: C29H28N2O6. Mole weight: 500.54. | |
| 15(R)-15-Methyl prostaglandin D2 | 15(R)-15-Methyl PGD2 is a selective, potent agonist for the CRTH2/DP2 receptor. Synonyms: 15(R)-15-methyl PGD2; 15(R)-15-methyl Prostaglandin D2. Grade: ≥95%. CAS No. 210978-26-0. Molecular formula: C21H34O5. Mole weight: 366.5. | |
| 15(R)-17-Phenyl trinor prostaglandin F2α | 15(R)-17-Phenyl trinor prostaglandin F2α is an impurity of the antiglaucoma agent Bimatoprost. It is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor. Synonyms: 15-epi Bimatoprost; 15(R)-Bimatoprost; 15(R)-17-phenyl trinor PGF2α; (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid. Grade: ≥98%. CAS No. 41639-71-8. Molecular formula: C23H32O5. Mole weight: 388.5. | |
| 15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester | 15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 value for the free acid forms of 15(R)-17-phenyl trinor PGF2α wa determined to be 30 nM in a FP receptor binding assay using the cat iris sphincter muscle. Synonyms: 9α,11α,15R-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid, isopropyl ester; 15-epi Bimatoprost isopropylester; 15(R)-Bimatoprost isopropyl ester; 15(R)-17-phenyl trinor PGF2α isopropyl ester; Isopropyl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl}-5-heptenoate; 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)-. Grade: 98%. CAS No. 130273-87-9. Molecular formula: C26H38O5. Mole weight: 430.59. | |
| 15(R)-Prostaglandin D2 | Many of the effects of prostaglandin D2 (PGD2) are transduced via a traditional 7-transmembrane GPCR, the DP1 receptor. 15(R)-15-methyl PGD2 is a surprisingly potent agonist at the DP2 receptor. Synonyms: 15(R)-PGD2; (5Z,9a,13E,15R)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic acid. Grade: ≥98%. CAS No. 59894-05-2. Molecular formula: C20H32O5. Mole weight: 352.5. | |
| 15(R)-Prostaglandin E1 | 15(R)-PGE1 is the unnatural C-15 stereoisomer of PGE1. Synonyms: 15(R)-PGE1; 15-epi PGE1; 15-Epiprostaglandin E1. Grade: ≥95%. CAS No. 20897-91-0. Molecular formula: C20H34O5. Mole weight: 354.5. | |
| 15(R)-Prostaglandin F2α | 15(R)-PGF2α is the C-15 epimer of the naturally occurring mammalian autacoid PGF2α. It has only 25% of the potency of PGF2α in hamster antifertility studies, which may be due to reduced affinity for FP receptors. Synonyms: 15-beta PGF2α; Prostaglandin F2α (15 beta epimer); 15-epi-PGF2alpha; 15R-Prostaglandin F2alpha. Grade: >99%. CAS No. 37658-84-7. Molecular formula: C20H34O5. Mole weight: 354.49. | |
| 15(R)-trans-Latanoprost (10.0 mg in 1. 0ml methyl acetate) | 15(R)-trans-Latanoprost is a prostaglandin analog, exhibiting remarkable efficacy in the research of both glaucoma and ocular hypertension, reducing intraocular pressure and thereby averting the perils of vision deterioration. Grade: > 95%. Molecular formula: C26H40O5. Mole weight: 432.61. | |
| 15(S)-Fluprostenol | 15(S)-fluprostenol is less active as an FP agonist than 15(R)-fluprostenol. Synonyms: 16-(3-(Trifluoromethyl)phenoxy)-17,18,19,20-tetranor-2,3-cis-didehydro-pgf1-alpha; (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoic acid. Grade: ≥98%. CAS No. 54276-24-3. Molecular formula: C23H29F3O6. Mole weight: 458.5. | |
| 15(S)-HEDE | 15(S)-HEDE has been identified in psoriatic skin scale extracts (undetermined 15-OH stereochemistry) and inhibits 5-LO (5-lipoxygenase) with an IC50 of 26 μM. Synonyms: (15S)-15-hydroxyicosa-11,13-dienoic acid. Grade: ≥98%. CAS No. 92693-04-4. Molecular formula: C20H36O3. Mole weight: 324.5. | |
| 15(S)-HEPE | 15(S)-HEPE is a polyunsaturated fatty acid that is a monohydroxy fatty acid synthesized from EPA by the action of 15-LO. Synonyms: 15S-hydroxy-5Z,8Z,11Z,13E,17Z-eicosapentaenoic acid. Grade: ≥95%. CAS No. 86282-92-0. Molecular formula: C20H30O3. Mole weight: 318.45. | |
| 15(S)-HETE ethanolamide | Arachidonoyl ethanolamide (AEA) was the first endogenous cannabinoid (CB) to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as THC. 15(S)-HETE ethanolamide is less potent than AEA at the CB1 receptor (Ki of 600 versus 90 nM). 15(S)-HETE ethanolamide also inhibits fatty acid amide hydrolase. Synonyms: 15(S)-hydroxy-N-(2-hydroxyethyl)-5Z,8Z,11Z,13E-eicosatetraenamide; 15(S)-HAEA. Grade: >98%. CAS No. 161744-53-2. Molecular formula: C22H37NO3. Mole weight: 363.5. | |
| 15(S)-HETrE | 15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of DGLA. It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 μM. Synonyms: (15S)-15-hydroxyicosa-8,11,13-trienoic acid. Grade: ≥98%. CAS No. 92693-02-2. Molecular formula: C20H34O3. Mole weight: 322.5. | |
| 15(S)-HpETE | 15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. Synonyms: (S)-15-hpete; 15-Hydroperoxyicosatetraenoate; 15-Hydroperoxyeicosatetraenoate. Grade: ≥98%. CAS No. 70981-96-3. Molecular formula: C20H32O4. Mole weight: 336.5. | |
| 15(S)-Latanoprost | An impurity of Latanoprost, a medication used to treat glaucoma and ocular hypertension. Synonyms: (15S)-Latanoprost; Latanoprost USP Related Compound B. Grade: > 95%. CAS No. 145773-22-4. Molecular formula: C26H40O5. Mole weight: 432.61. | |
| 16:0-18:1 PI(4)P Diammonium salt | 16:0-18:1 PI(4)P Diammonium salt, a phosphatidylinositol, is a complex molecule embedded within the cell membrane. It has been closely associated with pathologies such as cancer, Alzheimer's, and diabetes, lending it to extensive biomedical research. The salt is particularly notable for its capacity to regulate specific cellular pathways in drug development. Understanding the complex implications of this molecule requires a multidisciplinary approach, involving the integration of biochemistry, pharmacology, and medical sciences. Synonyms: 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-myo-inositol-4'-phosphate) (ammonium salt); D-myo-Inositol, 4-(dihydrogen phosphate) 1-[(2R)-3-[(1-oxohexadecyl)oxy]-2-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propyl hydrogen phosphate], ammonium salt (1:2). Grade: >99%. CAS No. 2260795-75-1. Molecular formula: C43H88N2O16P2. Mole weight: 951.11. | |
| 16:0 Azido Coenzyme A Ammonium salt | 16:0 Azido Coenzyme A Ammonium salt is a biochemical reagent mostly used in research related to lipid metabolism and protein modification studies. This product can also help to investigate possible new treatment approaches for metabolic disorders or diseases. Synonyms: 16-azidohexadecanoyl Coenzyme A (ammonium salt). Grade: >99%. CAS No. 2260670-37-7. Molecular formula: C37H74N13O17P3S. Mole weight: 1098.05. | |
| 16:0 Lyso PA (sodium salt) | 1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of five different G protein-coupled receptors (GPCRs) to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Synonyms: 1-hexadecanoyl-sn-glycero-3-phosphate (sodium salt); PA(16:0/0:0); 1-Palmitoyl lysophosphatidic acid sodium salt. Grade: ≥98%. CAS No. 17618-08-5. Molecular formula: C19H38NaO7P. Mole weight: 454.45. | |
| 16:0 Lyso PE | 16:0 Lyso PE is a naturally occurring lysophospholipid. 16:0 Lyso PE inhibits the growth of L. donovani promastigotes. It has been used to degranulate human eosinophils. Synonyms: 16:0 LPE; 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine; 1-Palmitoyl-2-hydroxy-sn-glycero-3-Phosphoethanolamine. Grade: ≥98%. CAS No. 53862-35-4. Molecular formula: C21H44NO7P. Mole weight: 453.55. | |
| 16:0 PA-PEG3-mannose Ammonium salt | The molecular weight and exact mass are averages based on the polydispersity of PEG. Synonyms: 1,2-dipalmitoyl-sn-glycero-3-phospho((ethyl-1',2',3'-triazole)triethyleneglycolmannose) (ammonium salt); D-L-Mannopyranoside, 2-[2-[2-[4-[(7R)-4-hydroxy-4-oxido-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacos-1-yl]-1H-1,2,3-triazol-1-yl]ethoxy]ethoxy]ethyl, ammonium salt (1:1). Grade: >99%. CAS No. 2260670-46-8. Molecular formula: C51H99N4O16P (average MW due to polydispersity of PEG). Mole weight: 1055.32. | |
| 16,16-Dimethyl prostaglandin A1 | 16,16-Dimethyl prostaglandin A1 is a metabolism resistant analog of PGA1. In vitro, it inhibits the viral replication in both HSV and HIV-1 infection systems at concentrations that do not adversely alter cellular DNA synthesis. Synonyms: Dmpga1; 16,16-Dimethylprostaglandin A1; 16,16-dimethyl Prostaglandin A1; 41692-24-4; 16,16-Dime-pga1; 16,16-dimethyl-PGA1; 7-[(1R,2S)-2-[(E,3R)-3-hydroxy-4,4-dimethyloct-1-enyl]-5-oxocyclopent-3-en-1-yl]heptanoic acid; 16,16-dimethyl-Prostaglandin A1; 5668IJK40E; Prosta-10,13-dien-1-oic acid, 15-hydroxy-16,16-dimethyl-9-oxo-, (13E,15R)-; 9-oxo-15R-hydroxy-16,16-dimethyl-10Z,13E-prostadienoic acid; 16,16-dimethyl PGA1; UNII-5668IJK40E; SCHEMBL5700532; CHEBI:156175; CTQQHQGBBMYJPT-DZFVFWAGSA-N; DTXSID401347768; HMS3648C15; LMFA03010085; AKOS040755003; PD021483; HY-116758; CS-0066467; SR-01000946197; SR-01000946197-1; Q27261379; 9-Oxo-15R-hydroxy-16,16-dimethylprosta-10,13E-dien-1-oic acid; 7-[(1R,2S)-2-[(E,3R)-3-hydroxy-4,4-dimethyl-oct-1-enyl]-5-oxo-cyclopent-3-en-1-yl]heptanoic acid. Grade: ≥98%. CAS No. 41692-24-4. Molecular formula: C22H36O4. Mole weight: 364.52. | |
| 16,16-Dimethyl prostaglandin A2 | 16,16-Dimethyl prostaglandin A2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. Synonyms: 16,16-dimethyl PGA2; (Z)-7-[(1R,2S)-2-[(E,3R)-3-hydroxy-4,4-dimethyloct-1-enyl]-5-oxocyclopent-3-en-1-yl]hept-5-enoic acid. Grade: ≥98%. CAS No. 41691-92-3. Molecular formula: C22H34O4. Mole weight: 362.5. | |
| 16,16-Dimethyl Prostaglandin E2 | 16,16-Dimethyl Prostaglandin E2, a prostaglandin E2 derivative, could induce an increase in hematopoietic stem cell (HSC) numbers in mouse model. Uses: Anti-ulcer agents. Synonyms: 16,16-Dimethyl-pge2; 16,16-dimethylprostaglandin E2; 16,16-Dimethyl-prostaglandin E2; dmpge2; (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-4,4-dimethyloct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid. Grade: >98%. CAS No. 39746-25-3. Molecular formula: C22H36O5. Mole weight: 380.52. | |
| 16,16-Dimethyl prostaglandin F2α | 16,16-Dimethyl prostaglandin F2α is a metabolically stable analog of PGF2α. Synonyms: 16,16-dimethyl PGF2α; 16,16-Dimethylprostaglandin F2alpha. Grade: ≥98%. CAS No. 39746-23-1. Molecular formula: C22H38O5. Mole weight: 382.5. | |
| 16(17)a-17R-Homodexamethasone sodium phosphate | An impurity of Dexamethasone, which is a corticosteroid medication used for inflammations. Synonyms: 9-Fluoro-11β,17a,21-trihydroxy-16β-methyl-16(17)a-homopregna-1,4-diene-3,16a,20-trione 21-(dihydrogen phosphate) disodium salt. Molecular formula: C22H28FNa2O8P. Mole weight: 516.4. | |
| 16(17)a-Homobetamethasone sodium phosphate | An impurity of Dexamethasone, which is a corticosteroid medication used for inflammations. Synonyms: 9-Fluoro-11β,17,21-trihydroxy-16β-methyl-16(17)a-homopregna-1,4-diene-3,16a,20-trione 21-(dihydrogen phosphate) disodium salt. Molecular formula: C22H28FNa2O8P. Mole weight: 516.4. | |
| 16(17)a-Homodexamethasone sodium phosphate | An impurity of Dexamethasone, which is a corticosteroid medication used for inflammations. Synonyms: 9-Fluoro-11β,17,21-trihydroxy-16α-methyl-16(17)a-homopregna-1,4-diene-3,16a,20-trione 21-(dihydrogen phosphate) disodium salt. Molecular formula: C22H28FNa2O8P. Mole weight: 516.4. | |
| 16,17-Dehydro Capsaicin | A dehydrogenated metabolite of Capsaicin. Synonyms: (6E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6,8-nonadienamide. Grade: > 95%. CAS No. 509101-57-9. Molecular formula: C18H25NO3. Mole weight: 303.4. | |
| 16(17)-Dehydro Levonorgestrel | An impurity of Levonorgestrel, an emergency contraceptive used to prevent pregnancy. Synonyms: 13-Ethyl-18,19-dinorpregna-4,16-dien-20-yn-3-one; Levonorgestrel Impurity 9; (8R,9S,10R,13S,14S)-13-Ethyl-17-ethynyl-1,2,6,7,8,9,10,11,12,13,14,15-dodecahydro-3H-cyclopenta[a]phenanthren-3-one. Grade: ≥95%. CAS No. 61921-57-1. Molecular formula: C21H26O. Mole weight: 294.44. | |
| 16,17-Dihydroheronamide C | 16,17-Dihydroheronamide C, an antifungal agent, is designed as a probe for analyzing the mode-of-action of heronamide C. Synonyms: (3E,5E,7E,9S,10R,11Z,13E,15E,20S)-9,10-dihydroxy-7,15-dimethyl-20-((2E,4E)-octa-2,4-dien-1-yl)azacycloicosa-3,5,7,11,13,15-hexaen-2-one. CAS No. 2698333-36-5. Molecular formula: C29H41NO3. Mole weight: 451.64. | |
| 1,6:2,3-Dianhydro-4-O-(2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyl)-b-D-mannopyranose | Purportedly an efficacious chemical in inhibiting the pathological propagation of bacteria and viruses, 1,6:2,3-Dianhydro-4-O-(2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyl)-b-D-mannopyranose is a vital substance involved in the biomedical field. Its mechanism of action involves significantly impeding the growth and spreading of deleterious microorganisms within the human body, resulting in the treatment and prevention of bacterial and viral infections. Synonyms: (2S,3R,4S,5R,6R)-2-(((1R,2S,4S,5R,6R)-3,8,9-Trioxatricyclo[4.2.1.02,4]nonan-5-yl)oxy)-6-(acetoxymethyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate. CAS No. 103702-87-0. Molecular formula: C20H26O13. Mole weight: 474.41. | |
| 1,6:2,3-Dianhydro-4-O-(2,3-di-O-benzyl-4,6-O-benzylidene-b-D-glucopyranosyl)-b-D-mannopyranose | 1,6:2,3-Dianhydro-4-O-(2,3-di-O-benzyl-4,6-O-benzylidene-b-D-glucopyranosyl)-b-D-mannopyranose is a potent compound used in biomedicine to inhibit the growth of various cancer cells. It can used to study breast, lung, and colon cancers. CAS No. 99541-22-7. Molecular formula: C33H34O9. Mole weight: 574.62. | |
| 1,6:2,3-Dianhydro-4-O-(2,3-di-O-benzyl-b-D-glucopyranosyl)-b-D-mannopyranose | 1,6:2,3-Dianhydro-4-O-(2,3-di-O-benzyl-b-D-glucopyranosyl)-b-D-mannopyranose is a compound prominently utilized in the flourishing biomedical industry, established as a potent antagonist of predefined pharmacological targets. This compound expediently facilitates the research and development of novel pharmaceutical interventions targeting specific facets of cancer. Molecular formula: C26H30O9. Mole weight: 486.51. | |
| 1,6:2,3-Dianhydro-4-O-(2,3-di-O-benzyl-β-D-glucopyranosyl)-β-D-mannopyranose | 1,6:2,3-Dianhydro-4-O-(2,3-di-O-benzyl-β-D-glucopyranosyl)-β-D-mannopyranose. Synonyms: 1,6:2,3-Dianhydro-4-O-[2,3-bis-O-(phenylmethyl)-β-D-glucopyranosyl]-β-D-mannopyranose. CAS No. 2088617-55-2. Molecular formula: C26H30O9. Mole weight: 486.51. | |
| 1,6:2,3-Dianhydro-4-O-(4,6-O-benzylidene-β-D-glucopyranosyl)-β-D-mannopyranose | 1,6:2,3-Dianhydro-4-O-(4,6-O-benzylidene-β-D-glucopyranosyl)-β-D-mannopyranose. Synonyms: 1,6:2,3-Dianhydro-4-O-[4,6-O-(phenylmethylene)-β-D-glucopyranosyl]-β-D-mannopyranose. CAS No. 150126-09-3. Molecular formula: C19H22O9. Mole weight: 394.37. | |
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