BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
3'-Azido-3'-deoxythymidine 2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester is a valuable compound used in biomedicine. With its excellent antiviral properties, it is instrumental in treating HIV infections. This compound acts as a prodrug, specifically targeting HIV reverse transcriptase, preventing viral replication and further progression of the disease. Synonyms: 3'-Azido-3'-deoxy-D-thymidine 2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester. Molecular formula: C23H29N5O13. Mole weight: 583.50.
3'-Azido-3'-deoxythymidine-5'-monophosphate lithium salt
3'-Azido-3'-deoxythymidine-5'-monophosphate lithium salt, an extraordinary antiviral pharmaceutical compound employed in the treatment of HIV/AIDS, showcases its potency by impeding the reverse transcriptase enzyme, an essential player in viral replication. With its roots in thymidine, this lithium salt not only bestows augmented cellular penetration but also amplifies antiviral efficacy against HIV. Molecular formula: C10H14N5O7P·xLi. Mole weight: 347.22 (free acid).
3'-Azido-3'-deoxythymidine 5'-monophosphate sodium salt
3'-Azido-3'-deoxythymidine 5'-monophosphate sodium salt is an indispensable element in the realm of biomedicine. It assumes a pivotal role as a significant intermediary during the production of antiviral medications, including Zidovudine (AZT). This compound emerges as a potent inhibitor of reverse transcriptase, thereby effectively combatting the relentless progression of HIV and AIDS. Synonyms: Zidovudine 5'-monophosphate sodium salt; AzTMP; 3'-Azido-3'-deoxy-D-thymidine 5'-monophosphate sodium salt. Grades: 97%. CAS No. 128506-29-6. Molecular formula: C10H13N5NaO7P. Mole weight: 369.23.
3'-Azido-3'-deoxythymidine 5'-triphosphate triethylammonium salt
3'-Azido-3'-deoxythymidine 5'-triphosphate triethylammonium salt is a valuable reagent used in biomedical research. It serves as an important precursor for synthesizing antiretroviral drugs utilized in the treatment of human immunodeficiency virus (HIV) infections. This compound acts as a nucleoside analog by inhibiting reverse transcriptase, an enzyme crucial for viral replication. Synonyms: Zidovudine 5'-triphosphate triethylammonium salt. Grades: 95%. CAS No. 127753-52-0. Molecular formula: C10H16N5O13P3·3C6H15N. Mole weight: 810.75.
3'-Azido-3'-deoxyuridine
3'-Azido-3'-deoxyuridine, renowned for its robust antiviral efficacy, is an exceptional nucleoside analogue. This nucleoside analogue unravels a remarkable mechanism of restraining viral replication through hampering the research and development of viral DNA. Synonyms: Uridine, 3'-azido-3'-deoxy-; 1-((2R,3R,4S,5S)-4-azido-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 70580-88-0. Molecular formula: C9H11N5O5. Mole weight: 269.21.
3'-Azido-5'-O-benzoyl-2',3'-dideoxyuridine
3'-Azido-5'-O-benzoyl-2',3'-dideoxyuridine, a compound widely utilized in the biomedical sector, holds immense value. Its predominant application lies in antiviral therapy for combating DNA viruses like herpes simplex virus and human immunodeficiency virus. Operating as a nucleoside analog, it obstructs viral replication and facilitates the suppression of crucial viral enzymes. Due to its distinctive configuration, it exhibits substantial prospects as an antiviral agent in the treatment of these viral afflictions. Synonyms: 3'-Azido-5'-O-benzoyl-2',3'-dideoxy-D-uridine. Molecular formula: C16H15N5O5. Mole weight: 357.32.
3'-Azido-5'-O-benzoyl-3'-deoxythymidine
3'-Azido-5'-O-benzoyl-3'-deoxythymidine is a formidable antiviral compound employed in the research of HIV infection, acting by impeding the indispensable reverse transcriptase enzyme crucial for viral replication. Synonyms: 1-[(2R,4S,5S)-4-azido-5-(phenylmethoxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione; 1-[(2R,4S,5S)-4-azido-5-(benzyloxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione. Grades: 98%. CAS No. 121456-55-1. Molecular formula: C17H17N5O5. Mole weight: 371.35.
3'-Azido-5'-O-tert-butyldimethylsilyl-2',3'-dideoxyuridine: A highly intricate and exceptionally potent antiviral compound, exquisitely effective in combatting a wide array of viral infections induced by both DNA and RNA viruses. Strikingly targeted towards viral reverse transcriptase, it profoundly attenuates the duplicative proclivities of HIV and various other retroviruses. Renowned for its unparalleled utility in the realms of relentless biomedical inquiry and pioneering pharmaceutical advancements, this invaluable entity resides at the forefront of progressive antiviral therapies. Synonyms: 3'-Azido-5'-O-tert-butyldimethylsilyl-2',3'-dideoxy-D-uridine. Molecular formula: C15H25N5O4Si. Mole weight: 367.48.
3'-Azido-5'- O-tert-butyldimethylsilyl-3'-deoxythymidine, commonly known as AZT, is a highly potent antiviral compound utilized in the therapeutic intervention against human immunodeficiency virus (HIV) infection. Mechanistically, it exerts its pharmacological action as a nucleoside reverse transcriptase inhibitor, effectively restraining the activity of the reverse transcriptase enzyme pivotal for viral replication. CAS No. 1254809-15-8. Molecular formula: C16H27N5O4Si. Mole weight: 381.51.
3'-Azido-N4-benzoyl-2',3'-dideoxycytidine
3'-Azido-N4-benzoyl-2',3'-dideoxycytidine, a formidable antiviral compound widely employed in the biomedical sector, exhibits remarkable efficacy against the pernicious pathogens of HIV and AIDS. Its unparalleled potency lies in its exceptional ability to suppress the reverse transcriptase enzyme, thereby impeding viral replication. Thus, this extraordinary product holds immense promise in the realm of therapeutics, offering a glimmer of hope for affliction-stricken individuals grappling with these formidable diseases. Grades: 98%. Molecular formula: C16H16N6O4. Mole weight: 356.34.
3'-Azido-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxycytidine, hailed as a paramount contender in the biomedical industry, exhibits remarkable efficacy as a potent antiviral agent. Renowned for its paramount significance in suppressing the replication mechanism of human immunodeficiency virus (HIV), it emerges as a breakthrough in the therapeutic armentarium of HIV infection. By perturbing the reverse transcriptase enzyme, this compound orchestrates an intricate dance, entailing the hindrance of viral DNA synthesis and the subsequent thwarting of viral replication. Molecular formula: C23H20N6O5. Mole weight: 460.44.
3'-Azido-N4-benzoyl-5'-O-tert-butyldimethylsilyl-2',3'-dideoxycytidine, a remarkable antiviral substance widely utilized in the biomedical field, exhibits potent efficacy against retroviral infections, particularly HIV. Functioning as a nucleoside reverse transcriptase inhibitor (NRTI), it proficiently hinders viral genetic material replication, effectively curbing the advancement of viral ailments. Profoundly valued within the scientific community, this compound stands as a vital tool in combating viral infections. Molecular formula: C22H30N6O4Si. Mole weight: 470.61.
3'-Azido-N4-benzoyl-5'-O-trityl-2',3'-dideoxyadenosine is an indispensable molecule in the biomedical realm, showcasing remarkable efficacy as an antiviral compound. It thwarts the conversion of viral RNA to DNA through reverse transcription. Molecular formula: C36H30N8O3. Mole weight: 622.68.
3'-Azido-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine, a vital element in the biomedical field, showcases immense complexity and variability. Its prominent application lies in the advancement of prospective antiviral therapeutics, predominantly aimed at RNA viruses. By obstructing viral replication, it demonstrates comprehensive antiviral efficacy against a diverse array of viruses. Molecular formula: C38H34N8O6. Mole weight: 698.73.
3'-Azido-N6-benzoyl-3'-deoxyadenosine
3'-Azido-N6-benzoyl-3'-deoxyadenosine, an extensively employed antiviral agent within the biomedical sector, exerts its effectiveness against DNA viruses, including herpes simplex virus (HSV) and human immunodeficiency virus (HIV). By impeding viral DNA synthesis, this compound exhibits exceptional prowess in thwarting viral replication, thereby presenting itself as a highly desirable and efficacious therapeutic intervention for combating these infections. Synonyms: 3'-azido-3-deoxy-N6-benzoyladenosine; 3'-azido-N-benzoyl-3'-deoxy-adenosine; N-[9-[(2R,3R,4S,5S)-4-azido-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]benzamide; N-Benzoyl-3'-azido-3'-deoxyadenosine. Grades: ≥95%. CAS No. 103597-10-0. Molecular formula: C17H16N8O4. Mole weight: 396.36.
3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine, a pivotal compound in the realm of biomedical research, holds immense promise. In the dynamic landscape of antiviral drug development, it assumes a paramount role in combatting viral infections, most notably HIV/AIDS. Its extraordinary molecular architecture enables the precise targeting of crucial enzymes, thus impeding viral replication. Molecular formula: C24H20N8O4. Mole weight: 484.47.
3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine, an esteemed biomedical marvel, boasts exceptional potency as an antiviral agent. With its unrivaled efficacy, this remarkable compound serves as a formidable weapon against the pernicious HIV, impeding its replication. Functioning as a nucleotide reverse transcriptase inhibitor, it disrupts the conversion of viral RNA to DNA, manifesting as a barrier to the proliferation of HIV. Grades: 95%. Molecular formula: C38H34N8O5. Mole weight: 682.73.
3'-b-C-Methylcytidine
3'-b-C-Methylcytidine, an eminent compound employed in the realm of biomedicine, proves pivotal in the amelioration of diverse ailments, including cancer and viral infections. With its remarkable capacity to impede neoplastic proliferation, this compound serves as an invaluable anti-cancer adjunct. Moreover, its inherent antiviral prowess positions it as a potent weapon against viral afflictions. Synonyms: Cytidine, 3'-C-methyl-; 3'-β-C-Methylcytidine; 3'-beta-C-Methylcytidine; 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-4-methyloxolan-2-yl]pyrimidin-2-one; 3'-C-methylcytidine. Grades: ≥95%. CAS No. 20724-72-5. Molecular formula: C10H15N3O5. Mole weight: 257.24.
3'-b-C-Methyl-N6-methyladenosine
3'-b-C-Methyl-N6-methyladenosine is a remarkable compound, holding immense potential in research of diverse ailments such as cancer and neurodegenerative disorders. Impressively, it performs as an influential suppressor of RNA methyltransferases, skillfully governing RNA metabolism and controlling gene expression. Synonyms: 3'-beta-C-Methyl-N6-methyladenosine; Adenosine, N-methyl-3'-C-methyl-; N-Methyl-3'-C-methyladenosine. Grades: ≥95%. CAS No. 565450-84-2. Molecular formula: C12H17N5O4. Mole weight: 295.29.
3'-b-C-Methyluridine
3'-b-C-Methyluridine, a compound highly regarded in the biomedical sector, showcases immense significance due to its broad applications. It manifests exceptional potential in combating various diseases, including cancer, viral infections, and autoimmune disorders. Notably, it possesses pharmacological attributes as an antineoplastic agent, effectively hindering viral replication and orchestrating the modulation of immune responses. The utilization of 3'-b-C-Methyluridine in drug development and comprehensive biomedicine investigations exhibits considerable promise, highlighting its paramount importance in scientific research. Synonyms: 3'-beta-C-Methyluridine; 1-(3-C-methyl-β-D-ribofuranosyl)uracil; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-4-methyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione; 3'-C-methyluridine; 3'-methyluridine. Grades: ≥95%. CAS No. 80541-15-7. Molecular formula: C10H14N2O6. Mole weight: 258.23.
3'-(Benzylamino)-3'-deoxyadenosine
3'-(Benzylamino)-3'-deoxyadenosine, a chemical compound, possesses a one-of-a-kind structure that facilitates its integration into DNA and ultimately leads to the destruction of cancerous cells. It serves a pivotal role in the development of drugs aimed at treating numerous types of cancer, primarily leukemia and lymphoma, while also demonstrating potential in treating prevalent viral infections such as hepatitis B and C. Its multipurpose nature and innovative molecular composition ensure it remains at the forefront of cancer research developments. Synonyms: 3'-Deoxy-3'-[(phenylmethyl)amino]-adenosine; Adenosine, 3'-deoxy-3'-[(phenylmethyl)amino]-. Grades: 97%. CAS No. 67313-10-4. Molecular formula: C17H20N6O3. Mole weight: 356.38.
3'-β-Amino-2',3'-dideoxy-5'-O-methoxytrityl-5-methyluridine, an intriguing and formidable nucleoside derivative, triumphantly thrives in the biomedical realm where it valiantly combats viral infections and specific cancer forms. Astonishingly, this compound showcases remarkable antiviral prowess against RNA viruses, thereby sparking immense interest as a potential candidate for antitumor interventions. Synonyms: 1-(3-Amino-2,3-dideoxy-5-O-methoxytrityl-β-D-threo-pentofuranosyl)-5-methyluracil; 3'-b-Amino-2',3'-dideoxy-5-methyl-5'-O-trityluridine; 1-(3-Amino-2,3-dideoxy-5-O-(triphenylmethyl)-β-D-threo-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 204688-08-4. Molecular formula: C29H29N3O4. Mole weight: 483.56.
3'-β-Amino-2',3'-dideoxyuridine
3'-β-Amino-2',3'-dideoxyuridine, an influential biomedical compound, is widely recognized for its remarkable antiviral properties. With extraordinary efficacy, it exhibits immense potential in combating viral infections originating from herpes simplex virus (HSV) and human immunodeficiency virus (HIV). Functioning as a nucleoside analog, this potent drug serves as a significant obstacle in viral replication by intricately interfering with the process of DNA synthesis. Synonyms: 1-(3-Amino-2,3-dideoxy-b-D-threo-pentafuranosyl)uracil; 1-((2R,4R,5S)-4-Amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2,4(1H,3H)-Pyrimidinedione, 1-(3-amino-2,3-dideoxy-β-D-threo-pentofuranosyl)-. Grades: ≥95%. CAS No. 101062-04-8. Molecular formula: C9H13N3O4. Mole weight: 227.22.
3'-beta-C-Methyl-5-methyluridine
3'-beta-C-Methyl-5-methyluridine is a biomedicine used for the treatment of certain viral infections and as an antiviral drug. It works by interfering with the replication process of the virus and inhibiting its growth. Synonyms: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-4-methyloxolan-2-yl]-5-methylpyrimidine-2,4-dione; Uridine, 5-methyl-3'-C-methyl-; 3'-β-C-Methyl-5-methyluridine; 5-Methyl-3'-C-methyluridine. Grades: ≥95%. CAS No. 934002-35-4. Molecular formula: C11H16N2O6. Mole weight: 272.25.
3'-beta-C-Methyladenosine
3'-beta-C-Methyladenosine is a groundbreaking biomedical compound, assuming a pivotal stance in the arena of drug discovery and scientific inquiry related cancer, viral affections, and immune-mediated pathogenesis. Synonyms: 3'-C-Methyladenosine; Adenosine, 3'-C-methyl-; 9-(3'-C-Methyl-β-D-ribofuranosyl)adenine; (2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 15397-13-4. Molecular formula: C11H15N5O4. Mole weight: 281.27.
3'-beta-C-Methylguanosine
3'-beta-C-Methylguanosine, a paramount compound in the realm of biomedicine, assumes a pivotal position. It not only serves as an active participant in the realm of antiviral therapeutics but also showcases promise as a prospective intervention against infectious ailments inflicted by RNA viruses. Its exceptional proficiency lies in its capacity to obstruct viral replication and RNA synthesis, which in turn manifests as an effective antiviral agent. Synonyms: 3'-C-Methylguanosine; 9-(3-C-methyl-β-D-ribofuranosyl)guanine; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-4-methyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one; 3'-β-C-Methylguanosine. Grades: ≥95%. CAS No. 115303-89-4. Molecular formula: C11H15N5O5. Mole weight: 297.27.
3-β-D-Ribofuranosyl-6-hydroxymethyl-furano[2,3-d]-pyrimidin-2-one, a highly potent antiviral compound, stands out as an exceptional pharmaceutical agent in combating diverse viral infections. Its extraordinary range of action encompasses a multitude of DNA and RNA viruses, including the notorious herpesviruses and retroviruses. By impeding nucleic acid synthesis, this compound exerts a remarkable antiviral activity, effectively inhibiting viral replication. Synonyms: 6-(Hydroxymethyl)-3-beta-D-ribofuranosylfuro[2,3-d]pyrimidin-2(3H)-one; 3-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-(hydroxymethyl)furo[2,3-d]pyrimidin-2(3H)-one. Grades: ≥95%. CAS No. 1058167-74-0. Molecular formula: C12H14N2O7. Mole weight: 298.25.
3'-β-Thymidine
As an intermediate in the production of fluorothymidine and phosphorylase derivatives 3'-β-Thymidine (Stavudine EP Impurity B) is used as an antiviral agent. Reverse transcriptase inhibitor. Synonyms: 1-(2-Deoxy-β-D-threo-pentofuranosyl)-5-methyluricil; 1-(2-Deoxy-b-D-xylofuranosyl)-5-methyluracil; 1-(2-Deoxy-β-D-threo-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-(2-Deoxy-β-D-threo-pentofuranosyl)-thymine; NSC 526738; Stavudine EP Impurity B; 1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 16053-52-4. Molecular formula: C10H14N2O5. Mole weight: 242.23.
3'-BHQ-1 CPG
3'-BHQ-1 CPG is a high-quality and specialized phosphoramidite that is crucial in the synthesis of oligonucleotides used in biomedical research for applications such as DNA sequencing, gene expression analysis, and antiviral drug development. Its unique black-hole-quencher (BHQ) design allows for the detection of specific genetic mutations and gene expression patterns, making it an essential tool in the study and treatment of diseases such as cancer and viral infections. Synonyms: 4'-(2-Nitro-4-toluyldiazo)-2'-methoxy-5'-methyl-azobenzene-4''-(N-ethyl-2-O-(4,4'-dimethoxytrityl))-N-ethyl-2-O-glycolate-CPG. Mole weight: 554.49.
3'-BHQ-1 Frits column (100nmol)
The 3'-BHQ-1 Frits column (100nmol) is an indispensable biomedical instrument facilitating drug exploration and investigation, particularly tailored for employment in high-performance liquid chromatography (HPLC) apparatus, serving to scrutinize and cleanse diverse medicinal preparations and substances. Synonyms: 3'-BHQ-1 Frits column.
3'-BHQ-1 Frits column (200nmol)
3'-BHQ-1 Frits column (200nmol) is an indispensable instrument deployed in the realm of biomedicine to fabricate oligonucleotides that flaunt fluorescence properties. Its composition entails a quintessential BHQ-1 quencher, pivotal in devising fluorogenic probes to ascertain the quantification and identification of DNA targets. Its implications are far-reaching and can be employed effectively in diagnosing infectious diseases, genetic anomalies, and oncogenic biomarkers. Synonyms: 3'-BHQ-1 Frits column.
3'-BHQ-2 CPG
3'-BHQ-2 CPG is a strategically-crafted synthetic phosphorothioate oligonucleotide, masterfully adorned with a 3'-Black Hole Quencher (BHQ-2) and 5'-dimethoxytrityl protected group. This illustrious product is pivotal in the oligonucleotide synthesis movement which looks towards the development of revolutionary oligonucleotide-based therapeutics to regulate gene expression, with exceeding ability. The medical industry envisages it to be the solution in the fight against malignant diseases, such as cancer and viral infections that pose a significant threat to human existence. Synonyms: 4'-(4-Nitro-phenyldiazo)-2'-methoxy-5'-methoxy-azobenzene-4''-(N-ethyl-2-O-(4,4'-dimethoxytrityl))-N-ethyl-2-O-glycolate-CPG. Mole weight: 556.47.
3'-BHQ-2 Frits column (100nmol)
3'-BHQ-2 Frits column (100nmol) is an indispensable instrument in the realm of biomedical research, serving a pivotal role in the labeling of nucleotides during oligonucleotide synthesis. The black hole quencher (BHQ) dye within the column functions as an impeccable quencher for fluorescent probes, rendering it optimally suited to applications that demand superior accuracy and precision including real-time PCR, as well as DNA sequencing. Moreover, this Frits column unequivocally proves its worth and potency in developing diagnostic assays for highly infectious and life-threatening diseases such as COVID-19. Synonyms: 3'-BHQ-2 Frits column.
3'-BHQ-2 Frits column (200nmol)
3'-BHQ-2 Frits column (200nmol) is a high-performance liquid chromatography (HPLC) column used for the purification of various oligonucleotides, including probes and primers for qPCR and gene expression analysis. Its unique design, with a 200nmol capacity and incorporation of 3'-BHQ-2, helps to improve sensitivity and reduce background fluorescence in downstream applications. This column is particularly useful in the diagnosis and treatment of infectious diseases, as well as for genetic research. Synonyms: 3'-BHQ-2 Frits column.
3'-BHQ-3 CPG
3'-BHQ-3 CPG, a modified nucleotide, is a vital component of oligonucleotide synthesis for scientific research. The merging of black hole quencher (BHQ) and 3' cytosine (C) modification endows it with magnified quenching capacity for fluorescent probes and enhanced nuclease stability that is imperative in the domain of diagnostics and therapeutics for addressing viral, cancerous, and immune disorders. Synonyms: 3-Diethylamino-5-phenylphenazium-7-diazobenzene-4''-(N-ethyl-2-O-(4,4'-dimethoxytrityl))-N-ethyl-2-O-glycolate-CPG. Mole weight: 597.63.
3'-BHQ-3 Frits column (100nmol)
3'-BHQ-3 Frits column (100nmol) is a valuable tool for those in the biomedical industry involved in drug discovery and disease research. This product aids in the purification and analysis of oligonucleotides used to treat a variety of diseases, including cancer, HIV, and genetic disorders. Its small particle size allows for efficient separation and removal of impurities, resulting in high-quality oligonucleotide samples for further study. Synonyms: 3'-BHQ-3 Frits column.
3'-BHQ-3 Frits column (200nmol)
3'-BHQ-3 Frits column (200nmol) is a sophisticated scientific apparatus meticulously developed for the purpose of conducting precise and meticulous experiments by utilizing the extraordinary capabilities of high-performance liquid chromatography (HPLC). Distinguished by its unprecedented 3'-BHQ-3 (BHQ = Black Hole Quencher) chemical composition, this exceptional column facilitates the efficacious damping of fluorescence emissions in test specimens. Accustomed to accommodate an impressive 200nmol loading capacity, this remarkable column is profoundly renowned for its remarkable proficiency in the purification and evaluation of minuscule molecules, peptides, and oligonucleotides. Synonyms: 3'-BHQ-3 Frits column.
3'-Biotin CPG 1000
3'-Biotin CPG 1000 is a commendable and superior biomedicine offering extensively employed within the biomedical realm, manifesting itself as an invaluable entity facilitating the composite amalgamation of biotinylated substances through the provision of unwavering solace.
3'-Biotin Frits column (200nmol)
3'-Biotin Frits column (200nmol) is intended for biomedical research endeavors, ingeniously crafted to cater to the specific demands of isolating and purifying biotin-labeled molecules. Its exceptional functionality facilitates meticulous scrutiny and identification of biotinylated compounds, imparting immeasurable insights into drug development, molecular diagnostics, and disease biomarkers. Execute your studies with utmost confidence, courtesy of this dependable and efficient separation apparatus. Synonyms: 3'-Biotin Frits column.
3'-BiotinTEG CPG
3'-BiotinTEG CPG, a vital ingredient, finds extensive application in the biomedicine sector. This imperative reagent is widely used in the synthesis of oligonucleotides coupled with biotin tags. It is a ubiquitous tool employed for the isolation and identification of diverse biomolecules like DNA and proteins. Furthermore, it plays a pivotal role in enhancing the diagnosis and treatment prospects for ailments such as cancer and viral infections by contributing to pioneering therapeutic and diagnostic agents. Synonyms: 1-Dimethoxytrityloxy-3-O-(N-biotinyl-3-aminopropyl)-triethyleneglycolyl-glyceryl-2-O-succinyl-long chain alkylamino-CPG. Mole weight: 569.61.
3'-Biotin TEG CPG 1000
3'-Biotin TEG CPG 1000, a highly sought-after chemical in the synthesis of biotinylated oligonucleotides, serves as a fundamental player in the biomedical industry. Its invaluable contributions are lauded in many critical procedures such as PCR amplification, DNA sequencing, and oligonucleotide hybridization assays, which collectively help in the detection and treatment of diverse illnesses ranging from cancer, infectious diseases to genetic disorders.
3'-BiotinTEG PS
3'-BiotinTEG PS, a vital chemical compound, is a binding reagent often employed in the highly advanced biomedicine industry. Mostly, it's used to develop targeted drug delivery systems and medical diagnostics, making it a remarkable tool in the field of biomedical research. With its high specificity and low toxicity, it's commonly employed to label proteins and nucleic acids, which can accurately detect a specific disease or drug target. Synonyms: 1-Dimethoxytrityloxy-3-O-(N-biotinyl-3-aminopropyl)-triethyleneglycolyl-glyceryl-2-O-succinyl-polystyrene. Mole weight: 569.61.
3'-Bromo-2',3'-dideoxy-5-methyluridine
3'-Bromo-2',3'-dideoxy-5-methyluridine, a compound of immense value in the biomedical industry, exhibits tremendous potential in the realm of antiviral therapies, especially for combatting RNA viral infections, exemplified by the notorious Hepatitis C. Synonyms: 3'-Bromo-3'-deoxythymidine; BrddT; 3'-Br-ddT; 3'-Bromo-2',3'-dideoxythymidine; 1-[(2R,4S,5R)-4-bromo-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione; 1-(3-bromo-2,3-dideoxy-β-D-erythro-pentofuranosyl)thymine. Grades: ≥95%. CAS No. 99785-51-0. Molecular formula: C10H13BrN2O4. Mole weight: 305.13.
3-Bromo-6-methylpicolinic acid
3-Bromo-6-methylpicolinic acid (CAS# 779344-30-8) is a useful research chemical. Synonyms: 3-bromo-6-methyl-2-pyridinecarboxylic acid; 3-bromo-6-methylpyridine-2-carboxylic acid. CAS No. 779344-30-8. Molecular formula: C7H6BrNO2. Mole weight: 216.03.
3-Bromoimidazo(1,2-A)Pyridine
3-Bromoimidazo(1,2-A)Pyridine (CAS# 4926-47-0) is a useful research chemical. Synonyms: 3-bromoimidazo[1,2-a]pyridine; 3-bromoimidazo[1,2-a]pyridine. CAS No. 4926-47-0. Molecular formula: C7H5BrN2. Mole weight: 197.03.
3'-Cholesterol CPG 1000
3'-Cholesterol CPG 1000 is a highly sought-after phosphoramidite building block, coveted by experts in the field for its impressive versatility and usefulness. Boasting numerous applications within the biomedical industry, its primary function is in the synthesis of oligonucleotides with cholesterol conjugates. Scientists and researchers alike utilize this remarkable product in their study of lipoprotein metabolism, and its effectiveness in the treatment of hypercholesterolemia-associated diseases such as atherosclerosis cannot be overstated.
3'-Cholesteryl-frits column (100nmol)
3'-Cholesteryl-frits column (100nmol) represents a sophisticated stationary phase utilized for liquid chromatography, that accurately separates and purifies cholesterol-containing molecules in diverse biological samples. The multifunctional and versatile column enables a comprehensive examination of lipoprotein composition, the diagnosis of lipid metabolism disorders, and offers a profound scope for developing therapeutic agents to combat cardiovascular diseases. Synonyms: 3'-Cholesteryl-frits column.
3'-Cholesteryl-TEG CPG
3'-Cholesteryl-TEG CPG is a bioactive and indispensable chemical used in biomedical research for drug discovery and development. Renowned for its exceptional capacity in oligonucleotide synthesis, where cholesterol conjugation is absolutely indispensable, it holds great promise in the fight against cholesterol-dependent diseases such as atherosclerosis and hypercholesterolemia. Its prowess in the arena is unchallenged and highly sought after. Synonyms: 1-Dimethoxytrityloxy-3-O-(N-cholesteryl-3-aminopropyl)-triethyleneglycol-glyceryl-2-O-succinoyl-long chain alkylamino-CPG. Mole weight: 755.97.
3'-CPR II CPG
3'-CPR II CPG, a vital tool in molecular biology, is renowned for unraveling the elusive role of Toll-like receptor 9 (TLR9) in shaping the immune system. In the domain of immunotherapy, the adjuvant supplements DNA vaccines and jumpstarts immune responses to eradicate cancer and infections. Dive into the intriguing world of 3'-CPR II CPG as its therapeutic potential has undergone rigorous scrutiny in pre-clinical and clinical trials. Synonyms: 3-(4,4'-Dimethoxytrityloxy)-2,2-(dicarboxymethylamido)propyl-1-O-succinoyl-long chain alkylamino-CPG. Mole weight: 79.98.
3'-CPR II CPG 1000
3'-CPR II CPG 1000, as a synthetic DNA molecule utilized in the biomedical industry, has been discovered to play a crucial role in invigorating the immune system against cancer, viral infections, and autoimmune diseases. This immune stimulant has the potential to amplify the effectiveness of drugs commonly used in such treatments by catalyzing an initial immune response. Additionally, 3'-CPR II CPG 1000 is being considered for employment in vaccine development to augment the immune response against antigens.
3-Cyanovinyl-9-(5'-O-DMT-2'-deoxyribofuranosyl)carbazole, an intriguing compound widely utilized in biomedicine, exhibits remarkable antitumor attributes. Its efficacy against diverse malignancies, including breast, lung, and colon cancer, has garnered substantial interest. By virtue of its distinctive chemical makeup, this prodigious product selectively targets malignant cells, impeding their proliferation while stimulating apoptosis. Its immense therapeutic potential confers profound value in the realm of cancer investigation and pharmaceutical advancement. CAS No. 1044273-26-8. Molecular formula: C41H36N2O5. Mole weight: 636.74.
3-Cyanovinylcarbazole phosphoramidite
3-Cyanovinylcarbazole phosphoramidite, an indispensable biomedicine product, finds its application in the synthesis of oligonucleotides for diverse scientific and medical purposes such as targeted drug delivery, gene therapy, and molecular diagnostics. It possesses a distinctive chemical configuration that facilitates effective conjugation with therapeutic molecules, thus elevating their stability and specificity. Synonyms: CNV-K. Grades: 95%. CAS No. 1157899-72-3. Molecular formula: C50H53N4O6P. Mole weight: 836.95.
3-Cyanovinylcarbazole Phosphoramidite (CNVK)
3-Cyanovinylcarbazole Phosphoramidite (CNVK) is a fundamental constituent for the purpose of the synthesis of oligonucleotide. The dissimilar chemical features of CNVK make it felicitous for the pragmatic incorporation of CNVK into oligonucleotides and, hence, an invaluable implement in the realm of biomedicine. CNVK-modified oligonucleotides have been utilized to target precise mRNA sequences, thereby proffering auspicious therapeutic prospects for diseases, viz. cancer and viral infections, amongst others. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-1'-(3-cyanovinylcarbazol-9-yl)-2'-deoxy-β-D-ribofuranosyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C50H53N4O6P. Mole weight: 836.95.
3'-Dabcyl CPG
3'-Dabcyl CPG, a nucleic acid synthesis product widely utilized in the biomedicine industry for oligonucleotide development, exhibits high-quality coupling efficiency. Moreover, it has proven efficacious in the treatment of a range of afflictions including cancer and viral infections, showcasing its superb utility in therapeutic applications. Synonyms: 1-Dimethoxytrityloxy-3-[O-(N-4'-carboxy-4-(dimethylamino)-azobenzene)-3-aminopropyl)]-propyl-2-O-succinoyl-long chain alkylamino-CPG. Mole weight: 462.44.
3'-Dabcyl-CPG-1000
3'-Dabcyl-CPG-1000 is a top-tier biomaterial extensively employed in the realm of compound, standing as an uncompromising pillar for oligonucleotide and peptide research and development. It finds remarkable utility in DNA sequencing investigations, gene therapeutic endeavors, and the fabrication of tailored drug transportation systems.
3'-Dabcyl frits column (100nmol)
The 3'-Dabcyl frits column (100nmol) is an indispensable tool utilized in the biomedicine industry for the meticulous analyzation and unravelling of molecules for research purposes, owing to its avant-garde chromatography mechanism. As a matter of fact, the column epitomizes distinct magnificence since its frits are loaded with the highly fluorescent 3'-Dabcyl, which serves as a potent quencher utilized in the DNA hybridization assays and consequently facilitates the detection of biomolecules such as peptides and proteins. Its therapeutic applications, including investigating the insidious nature of cancer, neurodegenerative diseases, and infectious diseases, render it a versatile pharmacologic agent with remarkable potential. Synonyms: 3'-Dabcyl frits column.
3'-Dabcyl PS
3'-Dabcyl PS, a molecular probe, finds its primary use in biomedical research, serving as a tool to detect nucleic acid interactions with other molecules. Owning to its commendable fluorescent properties, this molecular probe holds tremendous promise in the development of diagnostic assays for infectious diseases like HIV and Hepatitis C. Synonyms: 1-Dimethoxytrityloxy-3-[O-(N-4'-carboxy-4-(dimethylamino)-azobenzene)-3-aminopropyl)]-propyl-2-O-succinoyl-polystyrene. Mole weight: 462.44.
3'-Dabsyl CPG
3'-Dabsyl CPG is a solid support composed of controlled-pore glass (CPG) functionalized with the fluorescent dye Dabsyl. It is commonly used in oligonucleotide synthesis, specifically for the controlled and efficient attachment of nucleotides. The Dabsyl group allows for easy detection and monitoring during the synthesis process. This product is useful for researchers studying genetic diseases and designing drugs aimed at treating them. Synonyms: 1-Dimethoxytrityloxy-3-[O-(N-4'-sulfonyl-4-(dimethylamino)-azobenzene)-3-aminopropyl]-propyl-2-O-succinoyl-long chain alkylamino-CPG. Mole weight: 498.49.
3'-dA-CPG
3'-dA-CPG is a nucleotide analog consisting of 3'-deoxyadenosine covalently linked to a CPG (Controlled Pore Glass) support. It is used as a solid support in the synthesis of oligonucleotides and in DNA vaccination research. It has also been investigated for its potential in the treatment of viral infections and cancer. Synonyms: 5'-Dimethoxytrityl-N-benzoyl-3'-deoxyAdenosine, 2'-succinoyl-long chain alkylamino-CPG. Mole weight: 313.21.
3'-dC-CPG
3'-dC-CPG is a DNA product that plays an essential role in the biomedical industry. It is used to treat various viral diseases by stimulating the immune system to identify and eliminate infected cells. This is achieved by binding to Toll-like receptors and activating immune cells to produce antiviral cytokines. 3'-dC-CPG is also used in the development of vaccines and cancer therapies due to its ability to enhance the immune response against cancer cells. Synonyms: 5'-Dimethoxytrityl-N-benzoyl-3'-deoxyCytosine, 2'-succinoyl-long chain alkylamino-CPG 500. Mole weight: 289.18.
3-Deaza-2'-deoxyuridine-5'-triphosphate
3-Deaza-2'-deoxyuridine-5'-triphosphate is an impurity of 3-Deazauridine-5'-triphosphate Triethylamine Salt; the active metabolite of the anticancer drug 3-Deazauridine. 3-Deazauridine-5'-triphosphate Triethylamine Salt can suppress cytidine triphosphate synthetase activity in tumor cells. CAS No. 1881279-84-0. Molecular formula: C10H16NO14P3. Mole weight: 467.15.
3-Deaza-2'-O-methyluridine
3-Deaza-2'-O-methyluridine is a remarkable nucleoside analog extensively utilized in the biomedical sector with efficacy in restraining viral replication. Unquestionably, this compound's multifaceted attributes hold great potential in the research of viral infections and cancer. Synonyms: DTXSID90972626; 2-Hydroxy-1-(2-O-methylpentofuranosyl)pyridin-4(1H)-one; 2(1H)-Pyridinone, 4-hydroxy-1-(2-O-methyl-beta-D-ribofuranosyl)-. CAS No. 57165-33-0. Molecular formula: C11H15NO6. Mole weight: 257.24.
3-Deaza-3-methyl-dA CEP
3-Deaza-3-methyl-dA CEP, a pivotal compound within the biomedicine realm, boasts indispensability. Its principal application resides in the amalgamation of DNA analogs and the adjustment of nucleosides, serving as a catalyst for cutting-edge investigations. By assuming a critical role in anti-viral drug development and genetic disease analysis, this product furnishes invaluable perspectives on diverse therapeutic interventions. Synonyms: Benzamide, N-benzoyl-N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-beta-D-erythro-pentofuranosyl]-7-methyl-1H-imidazo[4,5-c]pyridin-4-yl]-; DTXSID001098448; N-Benzoyl-N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-beta-D-erythro-pentofuranosyl]-7-methyl-1H-imidazo[4,5-c]pyridin-4-yl]benzamide. CAS No. 1031750-37-4. Molecular formula: C56H59N6O8P. Mole weight: 975.08.
3-Deaza-3'-O-methyluridine
3-Deaza-3'-O-methyluridine is a paramount compound specifically tailored for research of RNA-associated afflictions. This unparalleled compound substantially propels the investigation of viral maladies. Synonyms: 4-Hydroxy-1-(3-O-methyl-b-D-ribofuranosyl)-2(1H)-Pyridinone. Molecular formula: C11H15NO6. Mole weight: 257.24.
3-Deazaadenosine
3-Deazaadenosine (3-DZA) is an inhibitor of SAH hydrolase (Ki = 3.9 μM). Synonyms: Deaza-Ado; (2R,3R,4S,5R)-2-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 3-Deaza-rA; 1-(beta-D-ribofuranosyl)-1H-imidazo[4,5-c]pyridin-4-amine; 4-Amino-1-(β-D-ribofuranosyl)-1H-imidazo(4,5)-pyridine. Grades: ≥97% by HPLC. CAS No. 6736-58-9. Molecular formula: C11H14N4O4. Mole weight: 266.26.
3-Deazaadenosine hydrochloride
It is an S-adenosine homocysteine hydrolase inhibitor. It has anti-inflammatory effects, inhibiting leukocyte adhesion and chemotaxis, lymphocyt-mediated cytolysis, phagocytosis, degranulation and NF-κB signal transduction. Synonyms: 3-Deaza-Adenosine hydrochloride; 3-Deaza-rA Hcl; 1-(β-D-Ribofuranosyl)-1H-imidazo[4,5-c]pyridin-4-amine hydrochloride (1:1); 1H-Imidazo[4,5-c]pyridin-4-amine, 1-β-D-ribofuranosyl-, hydrochloride (1:1). Grades: ≥97% by HPLC. CAS No. 86583-19-9. Molecular formula: C11H15ClN4O4. Mole weight: 302.71.
3-Deazauridine-5'-triphosphate sodium salt
3-Deazauridine-5'-triphosphate sodium salt, an indispensable molecule within the biomedical realm, assumes the mantle as a prospective panacea against an array of maladies including viral afflictions and malignant neoplasms. Given its idiosyncratic chemical attributes, this substance occupies an imperative niche, steering the course of targeted pharmacotherapy and groundbreaking remedial modalities. Grades: 90%. Molecular formula: C10H16NO15P3·xNa. Mole weight: 483.15 (free acid).
3-Deazauridine-5'-triphosphate Triethylamine Salt
3-Deazauridine-5'-triphosphate Triethylamine Salt is the active metabolite of the anticancer drug 3-Deazauridine and can suppress cytidine triphosphate synthetase activity in tumor cells. Synonyms: 1-[5-O-[Hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-2, 4 (1H, 3H) -pyridinedione Triethylamine Salt; 3-Deaza-UTP Triethylamine Salt; 3-Deazauridine Triphosphate Triethylamine Salt. Molecular formula: C10H16NO15P3 XC6H15N. Mole weight: 483.15.
3'-Deoxy-2'-O-methyladenosine
3'-Deoxy-2'-O-methyladenosine, an indispensable biomedical compound, embraces immense potential in the amelioration of diverse ailments. Through its profound impact on RNA modifications and epigenetic regulation, this exceptional substance introduces itself as a cardinal player in the combat against cancer and neurodegenerative afflictions. With its exquisite ability to manipulate targeted routes inclusive of DNA reparation and protein synthesis, the realm of biomedicine is blessed with a groundbreaking therapeutic intervention. Synonyms: 3'-Deoxy-2'-O-methyl-D-adenosine; 2'-O-Methyl-3'-deoxyadenosine. Grades: 98%. Molecular formula: C11H15N5O3. Mole weight: 265.27.