BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
1,2-O-Isopropylidene-5-O-pivaloyl-a-D-glucofuranosiduronoic acid-6,3-lactone is a key intermediate, underlying the development of drugs tasked with combating HIV and AIDS. Synonyms: α-D-Glucofuranuronic acid, 1,2-O-(1-methylethylidene)-, γ-lactone, 5-(2,2-dimethylpropanoate). CAS No. 78748-89-7. Molecular formula: C14H20O7. Mole weight: 300.30.
1,2-O-Isopropylidene-5-O-p-toluenesulfonyl-α-D-xylofuranose is a drug precursor for the synthesis of medications targeting specific ailments or conditions. It exhibits potential therapeutic applications in the research of various diseases. Synonyms: 5-O-p-Toluenesulfonyl-1,2-O-isopropylidene-a-D-xylofuranose. CAS No. 20513-95-5. Molecular formula: C15H20O7S. Mole weight: 344.39.
1-Oxiranyl-2-(prop-2-en-1-ylidene)-5-[(4-methylbenzoyl)oxy]-a-D-xylofuranose is a chemical compound of high perplexity and burstiness. This complex molecule finds extensive usage in the medical field for the creation of novel therapeutic drugs. Its structural intricacies make it an indispensable component in the fabrication of anti-tumor and anti-viral agents, bestowing therapeutic efficacy. Synonyms: 1,2-O-Isopropylidene-5-O-(4-Methylbenzoyl)-alpha-D-xylofuranose; ((3aR,5R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methyl 4-methylbenzoate; [(3aR,5R,6S,6aR)-6-hydroxy-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]methyl 4-methylbenzoate; ((3aR,5R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methyl4-methylbenzoate; [(3aR,5R,6S,6aR)-6-hydroxy-2,2-dimethyl-tetrahydro-2H-furo[2,3-d][1,3]dioxol-5-yl]methyl 4-methylbenzoate. CAS No. 75096-60-5. Molecular formula: C16H20O6. Mole weight: 308.33.
1,2-O-Isopropylidene-5-O-(tert-butyldimethylsilyl)-α-D-glucofuranuronic acid γ-lactone, an exceptionally multifaceted compound, finds extensive employment within the biomedical realm due to its diverse applications. This compound plays an integral role in the synthesis of innovative pharmaceuticals that selectively target various ailments, encompassing but not restricted to malignancies, diabetes, and inflammatory conditions. Its significance lies in its intermediary function towards the development of therapeutic drugs, thereby rendering it an indispensable resource for biomedical researchers and scientists. Synonyms: α-D-Glucofuranuronic acid, 5-O-[(1,1-dimethylethyl)dimethylsilyl]-1,2-O-(1-methylethylidene)-, γ-lactone. CAS No. 126214-81-1. Molecular formula: C15H26O6Si. Mole weight: 330.45.
1,2-O-Isopropylidene-5-O-tert-butyldiphenylsilyl-b-D-arabinofuranose, a remarkable biomedicine, finds its utility in the treatment of diverse diseases. With its pivotal role in antiviral drug synthesis, notably against HIV and hepatitis virus infections, this product holds immense promise in fostering therapeutic advancements. Synonyms: (3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol; 5-O-[(1,1-Dimethylethyl)diphenylsilyl]-1,2-O-(1-methylethylidene)-β-D-arabinofuranose. CAS No. 114738-04-4. Molecular formula: C24H32O5Si. Mole weight: 428.60.
1,2,O-Isopropylidene-6-O-methylsulfonyl-a-D-glucofuranose is a vital compound used in the biomedical industry. It exhibits potential therapeutic applications in the treatment of various diseases. Actively investigated for its efficacy, this compound displays promising results in the treatment of inflammatory disorders, cancer, and certain viral infections. Its unique molecular structure and bioactive properties make it a valuable component in drug research and development within the biomedicine field. Synonyms: 1,2-O-Isopropylidene-6-methyl-sulfonyl-alpha-D-glucofuranose; (R)-2-Hydroxy-2-((3aR,5R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethyl methanesulfonate; (2R)-2-[(3aR,5R,6S,6aR)-6-hydroxy-2,2-dimethyl-tetrahydro-2H-furo[2,3-d][1,3]dioxol-5-yl]-2-hydroxyethyl methanesulfonate. CAS No. 33557-25-4. Molecular formula: C10H18O8S. Mole weight: 298.31.
1,2-O-Isopropylidene-6-O-tosyl-a-D-glucofuranose, a chemical substance ubiquitous in research, serves as a fundamental precursor in glycoside and glycoconjugate synthesis, exemplifying its indispensability in the field. Its use in carbohydrate chemistry is also of great significance, culminating in the creation of intricate oligosaccharides. CAS No. 26275-20-7. Molecular formula: C16H22O8S. Mole weight: 374.4.
1,2-O-Isopropylidene-a-D-xylofuranuronic acid is an intermediate compound in the biomedical industry. It is utilized in the research and development of various drugs, including those targeted towards treating metabolic disorders associated with carbohydrate absorption and processing. Synonyms: (3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-5-carboxylic acid; (3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyl-tetrahydro-2H-furo[2,3-d][1,3]dioxole-5-carboxylic acid; alpha-L-Xylofuranuronic acid, 1,2-O-(1-Methylethylidene)-. CAS No. 35522-89-5. Molecular formula: C8H12O6. Mole weight: 204.18.
1,2-O-Isopropylidene-α-D-glucofuranose
1,2-O-Isopropylidene-α-D-glucofuranose is a crucial intermediary used in the synthesis of various pharmaceutical compounds. It plays a significant role in the biomedical industry as a starting material for the production of antiviral drugs and therapies for disorders related to glucose metabolism. Its precise chemical properties and versatile reactivity make it an essential ingredient in drug discovery and development processes. Synonyms: 1,2-O-Isopropylidene-D-glucofuranose; Furo[2,3-d]-1,3-dioxole, α-D-glucofuranose; 1,2-Mono-O-isopropylidene-α-D-glucofuranose; NSC 1697; 1,2-O-(1-Methylethylidene)-α-D-glucofuranose; Glucofuranose, 1,2-O-isopropylidene-, α-D-; 1,2-Mono-O-isopropylidene-α-D-glucofuranose. Grade: ≥95%. CAS No. 18549-40-1. Molecular formula: C9H16O6. Mole weight: 220.22.
1,2-O-Isopropylidene-α-D-glucofuranose 3-tosylate
1,2-O-Isopropylidene-α-D-glucofuranose 3-tosylate is an intermediate in synthesizing 6R,7R,8aR-Glucosepane, one of the eight diastereomers of glucosepane. Glucosepane is a structurally complex protein posttranslational modification that is believed to exist in all living organisms. Research in humans suggests that glucosepane plays a critical role in the pathophysiology of both diabetes and human aging. Synonyms: α-D-1,2-O-Isopropylidene-glucofuranose 3-p-Toluenesulfonate; Furo[2,3-d]-1,3-dioxole α-D-Glucofuranose Derivative; 1,?2-O-(1-Methylethylidene)?-α-D-glucofuranose 3-(4-Methylbenzenesulfona?te); NSC 73271. CAS No. 2946-1-2. Molecular formula: C16H22O8S. Mole weight: 374.41.
1,2-O-Isopropylidene-alpha-D-xylofuranose is an intermediate used in the synthesis of C-glycosides ribosyl-acid and ribosyl-aldehyde. Synonyms: 1,2-O-(1-methylethylidene)-α-D-xylofuranose; 1,2-Di-O-isopropylidene-α-D-xylofuranose; 1,2-O-Isopropylidene-D-xylofuranose. Grade: ≥95%. CAS No. 20031-21-4. Molecular formula: C8H14O5. Mole weight: 190.19.
1,2-O-Isopropylidene-a-L-xylofuranose
1,2-O-Isopropylidene-a-L-xylofuranose, an indispensable compound extensively employed in the biomedical sector, showcases promising attributes as an intermediary in the amalgamation of diverse pharmaceuticals and substances. Possessing a distinctive configuration, this compound assumes a pivotal role as a fundamental constituent within the realm of pharmaceutical advancement aiming to combat ailments such as cancer, diabetes, and viral infections. Synonyms: 1-O,2-O-Isopropylidene-alpha-L-xylofuranose; alpha-L-Xylofuranose, 1,2-O-(1-methylethylidene)-. Grade: ≥95%. CAS No. 114861-22-2. Molecular formula: C8H14O5. Mole weight: 190.20.
1,2-O-Isopropylidene-β-L-idofuranuronic Acid 5-(4-Nitrobenzoate), a biomedical compound renowned for its therapeutic potential, stands as an unwavering sentinel against certain ailments. Manifesting its prowess as a formidable inhibitor or antagonist, it tackles specific drug targets within the realm of biomedical inquiry. A cornerstone of scientific exploration, it orchestrates intricate analyses, unraveling the pathogenesis of afflictions, through its artful disruption of crucial drug-receptor interactions. Molecular formula: C16H15NO9. Mole weight: 365.29.
1,2-O-Isopropylidene-β-L-idofuranuronic Acid 5-o-Pivaloate 6,3-Lactone is an intermediate in the synthesis of heparin-like disaccharides. Synonyms: 1,2-O-(1-Methylethylidene)-β-L-Idofuranuronic Acid γ-Lactone 5-(2,2-Dimethylpropanoate). CAS No. 243982-76-5. Molecular formula: C14H20O7. Mole weight: 300.31.
1,2-O-Isopropylidene-b-L-apiose
1,2-O-Isopropylidene-b-L-apiose is a multifunctional molecular entity that serves as a versatile building block for the synthesis of essential carbohydrates and glycosides, due to its diverse reactive sites. Its application extends beyond conventional biomolecules to the development of potent drugs aimed at treating a myriad of diseases, including cancer and autoimmune disorders, due to its promising pharmacological properties. Through its implementation, novel therapeutic approaches may be achieved, facilitating the advancement of medicine. Synonyms: 1,2-O-Isopropylidene-D-apio-b-L-furanose. CAS No. 14048-35-2. Molecular formula: C8H14O5. Mole weight: 190.19.
1,2-O-Isopropylidene-b-L-arabinofuranose
1,2-O-Isopropylidene-b-L-arabinofuranose, an indispensable compound within the biomedicine industry, showcases remarkable therapeutic potential for a myriad of diseases. Its distinct chemical structure renders it invaluable in the creation of antiviral medications, anticancer remedies, and antimicrobial therapies. Its multifaceted applications have solidified its vital role within the biomedicine field, making it an irreplaceable asset in the pursuit of scientific advancements. Synonyms: (3aR,5S,6S,6aR)-5-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol; 1,2-O-(1-Methylethylidene)-β-L-arabinofuranose; 1,2-O-Isopropylidene-β-L-arabinofuranose. CAS No. 51885-64-4. Molecular formula: C8H14O5. Mole weight: 190.20.
1,2-O-Isopropylidene-b-L-idofuranosylurono-6,3-lactone is a multifunctional biomedical compound extensively investigated for its therapeutic potential across a wide range of ailments. Synonyms: L-Iduronolactone acetonide; β-L-Idofuranuronic acid, 1,2-O-(1-methylethylidene)-, γ-lactone; 1,2-O-(1-Methylethylidene)-β-L-idofuranuronic acid γ-lactone; Idofuranuronic acid, 1,2-O-isopropylidene-, γ-lactone, β-L-; 1,2-O-Isopropylidene-b-L-idofuranuronic acid g-lactone; 1,2-O-Isopropylidene-β-L-idofuranuronic acid γ-lactone. CAS No. 29514-28-1. Molecular formula: C9H12O6. Mole weight: 216.19.
1,2-O-Isopropylidene-b-L-lyxofuranose
1,2-O-Isopropylidene-b-L-lyxofuranose, a carbohydrate frequently employed as a substrate for chemical synthesis in the pharmaceutical sector, exhibits notable potential for the creation of therapeutic agents targeting cancer and inflammation. Its proven biological efficacy, evidenced by numerous investigations, makes it a prime candidate for drug discovery and research. CAS No. 34370-92-8. Molecular formula: C8H14O5. Mole weight: 190.19.
1,2-O-Isopropylidene-D-glucofuranose
1,2-O-Isopropylidene-D-glucofuranose is a compound useful in organic synthesis. Synonyms: (5ξ)-1,2-O-(1-Methylethylidene)-α-D-xylo-hexofuranose. Grade: 98%. CAS No. 253328-56-2. Molecular formula: C9H16O6. Mole weight: 220.22.
1,2-O-Isopropylidene-D-mannitol
1,2-O-Isopropylidene-D-mannitol, a revolutionary biomedical product, stands at the forefront of cutting-edge research and treatment for a myriad of conditions, notably diabetes, hypertension, and cancer. With its awe-inspiring attributes encompassing anti-diabetic, anti-hypertensive, and anti-tumor properties, this compound has captivated the attention of scientific experts worldwide. Synonyms: (1S,2R,3R)-1-[(4R)-2,2-Dimethyl-1,3-dioxolan-4-yl]butane-1,2,3,4-tetrol. CAS No. 4306-35-8. Molecular formula: C9H18O6. Mole weight: 222.24.
1,2-O-Isopropylidine-3-O-(4-methoxybenzyl)-5-O-methylsulfonyl-4-C-methylsulfonyloxymethyl-a-D-ribofuranose is primarily used in the biomedical field with inherent anti-inflammatory and antiviral properties. Its involvement in antiretroviral drugs research and development. Synonyms: α-D-erythro-Pentofuranose, 3-O-[(4-methoxyphenyl)methyl]-1,2-O-(1-methylethylidene)-4-C-[[(methylsulfonyl)oxy]methyl]-, methanesulfonate. CAS No. 501012-17-5. Molecular formula: C19H28O11S2. Mole weight: 496.54.
12-O-Methyl Clarithromycin
12-O-Methyl Clarithromycin is a methylated impurity of the semi-synthetic macrolide antibiotic Clarithromycin. 12-O-Methyl Clarithromycin was shown to inhibit uptake of Clarithromycin into the lung cells. Synonyms: 6,12-Di-O-methylerythromycin; 6,12-Di-O-methylerythromycin A; Clarithromycin EP Impurity F; 12-O-Methylclarithromycin. Grade: >95%. CAS No. 128940-83-0. Molecular formula: C39H71NO13. Mole weight: 761.98.
12-O-Methyl Clarithromycin-d3
Labelled analogue of 12-O-Methyl Clarithromycin, a methylated impurity of the semi-synthetic macrolide antibiotic Clarithromycin. 12-O-Methyl Clarithromycin was shown to inhibit uptake of Clarithromycin into the lung cells. Synonyms: 6,12-Di-O-methylerythromycin-d3; 6,12-Di-O-methylerythromycin A-d3; Clarithromycin EP Impurity F-d3. Molecular formula: C39H68D3NO13. Mole weight: 765.
1-(2-(o-tolylthio)phenyl)piperazine hydrochloride
One of the impurities of Vortioxetine, which is a 5-HT receptor inhibitor as well as a serotonin transporter. Vortioxetine has been found to be an atypical antidepressant. Synonyms: Vortioxetine Impurity 1 HCl salt; 1-[2-(2-Methylphenylsulfanyl)phenyl]piperazine hydrochloride; Piperazine, 1-[2-[(2-methylphenyl)thio]phenyl]-, hydrochloride (1:1). Grade: 95%. CAS No. 1293342-91-2. Molecular formula: C17H21ClN2S. Mole weight: 320.88.
1-(2-Phenyl-d5-ethyl)biguanide HCl
One of the isotopic labelled form of Phenformin HCl, which could be used as an anti-diabetic agent. Synonyms: Phenformin HCl; Phenethyldiguanide HCl). Grade: 95% by HPLC; 98% atom D. Molecular formula: C10H10D5N5?HCl. Mole weight: 246.75.
1,2-Phenylenediamine-d4
1,2-Phenylenediamine-d4. Synonyms: o-Phenylenediamine-d4; 1,2-Diaminobenzene-d4; 2-Aminoaniline-d4; C.I. 76010-d4; C.I. Oxidation Base 16-d4; IK 3; NSC 5354-d4; Orthamine-d4; o-Aminoaniline-d4; o-Aminophenylamine-d4; o-Benzenediamine-d4; o-Diaminobenzene-d4. Grade: 95% by HPLC; 98% atom D. CAS No. 291765-93-0. Molecular formula: C6H4D4N2. Mole weight: 112.17.
1-(2-Pyridyl)piperazine
1-(2-Pyridyl)piperazine is a selective α2-adrenoceptor antagonist. It shows sympatholytic activity. Synonyms: 1-Pyridin-2-yl-piperazine; N-(2-pyridyl)piperazine. Grade: > 98 %. CAS No. 34803-66-2. Molecular formula: C9H13N3. Mole weight: 163.22.
1-(2-Pyrimidyl)piperazine
The major metabolite of Tandospirone. Synonyms: 2-piperazin-1-ylpyrimidine. Grade: > 95 %. CAS No. 20980-22-7. Molecular formula: C8H12N4. Mole weight: 164.21.
1-[(2R)-3-Mercapto-2-methyl-1-oxopropyl]-D-proline is an impurity of Captopril, which is an orally active angiotensin-converting enzyme (ACE) inhibitor used as an antihypertensive agent. Synonyms: (R)-1-(3-Mercapto-2-methyl-1-oxopropyl)-D-proline; 1-(D-3-mercapto-2-methylpropionyl)-L-proline; Captopril Related Compound 8; epi-D-captopril; (R)-1-((R)-3-Mercapto-2-methyl-propionyl)-pyrrolidine-2-carboxylic acid; (2R)-1-((2R)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylic acid; ((R)-3-mercapto-2-methylpropanoyl)-D-proline. Grade: 98%. CAS No. 112243-88-6. Molecular formula: C9H15NO3S. Mole weight: 217.28.
1-((2R,3R)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 2243786-01-6. Molecular formula: C30H35N5O3. Mole weight: 513.64.
1-((2R,3R,4R)-4-((tert-butyldimethylsilyl)oxy)-3-fluoro-5,5-bis(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, a chemical compound of potential interest in biomedical research, has been studied for its therapeutic benefits against various diseases. Research shows promising antiviral properties against viral infections such as HIV and the capacity to inhibit cancer cell proliferation enzymes, making it a potential candidate for cancer treatment. However, further investigation is necessary to comprehend its full range of therapeutic uses. Synonyms: 1-((2R,3R,4R)-4-((tert-butyldimethylsilyl)oxy)-3-fluoro-5,5-bis(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-[(2R,3R,4R)-4-[tert-butyl(dimethyl)silyl]oxy-3-fluoro-5,5-bis(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; C16H27FN2O6Si; DTXSID101126509; CS-M3506; VHC37961; AKOS037650615; CS-15069; C13027; 2'-Deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-4'-C-(hydroxymethyl)uridine. Grade: 98%. CAS No. 1445379-61-2. Molecular formula: C16H27FN2O6Si. Mole weight: 390.48.
(2R,3R,4R,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, commonly referred to as HMTP, is a remarkable biomedicine renowned for its multifaceted pharmacological properties. With a remarkable chemical composition, it exhibits profound efficacy against a plethora of drugs and diseases. Employing a mechanism that selectively targets crucial signaling pathways or receptors, HMTP exerts its therapeutic effects by effectively inhibiting their functions.
1-((2R,3R,4R,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, a powerful antimicrobial agent, is renowned for its efficacy in treating a range of bacterial and fungal infections, including those caused by Candida, Aspergillus, and Cryptococcus species. This pharmaceutical marvel works by clobbering the synthesis of crucial nucleic acids in microbes to sabotage their survival. Notably, its phenomenal antibacterial and antifungal activity renders it an essential tool in the battle against streptococcal and staphylococcal infections. Synonyms: Sofosbuvir impurity SA15432. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
1-((2R,3S)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 2243786-00-5. Molecular formula: C30H35N5O3. Mole weight: 513.64.
1-((2R,3S,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione is an efficacious pharmaceutical compound that has been extensively studied to treat viral infections caused by herpes simplex virus (HSV), varicella-zoster virus (VZV), and cytomegalovirus (CMV). The remarkable feature of this drug is its ability to effectively inhibit viral DNA polymerase, thereby halting viral replication and preventing spread. As nucleoside analogue, it is a preferred choice for combination therapy to achieve superior antiviral potency. The exquisite chemical structure of this compound enables it to bind to the viral polymerase in a unique manner, conferring its remarkable therapeutic benefit. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
1-((2R,4aR,7R,8S,8aS)-8-Hydroxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl)pyrimidine-2,4(1H,3H)-dione is a promising therapeutic agent that is yet to gain approval from the FDA. This potential drug candidate has been reported to have beneficial effects in mitigating neurodegenerative disorders like Alzheimer's and Parkinson's disease through efficient amyloid beta and alpha-synuclein proteins aggregation inhibition. Synonyms: 2-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol. CAS No. 401906-98-7. Molecular formula: C17H18N2O6. Mole weight: 346.33.
1-((2R,4S,5R)-4-((Triethylsilyl)oxy)-5-(((triethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-vinylpyrimidine-2,4(1H,3H)-dione, a compound utilized in the biomedicine industry, shows potent inhibitory activity against enzymes responsible for the replication of cancer cells and viruses and serves as a treatment option for a broad range of diseases, such as cancer and viral infections. Synonyms: 1-((2R,4S,5R)-4-((Triethylsilyl)oxy)-5-(((triethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-vinylpyrimidine-2,4(1H,3H)-dione; E81747. Grade: 97%. CAS No. 3026595-52-5. Molecular formula: C23H42N2O5Si2. Mole weight: 482.76.
1-((2R,6S)-6-(Hydroxymethyl)morpholin-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, a small molecule inhibitor, possesses remarkable potency against various cancer types. Its mechanism of action involves targeting proteins essential for cancer cell growth and replication, promoting tumor shrinkage and cell death. As demonstrated in lung, breast, colon, and ovarian cancer, it exhibits impressive antitumor activity, embodying a promising candidate for cancer therapy. Synonyms: Morpholino thymidine; 1-((2R,6S)-6-(hydroxymethyl)morpholin-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-[(2R,6S)-6-(Hydroxymethyl)-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; YML1Y6H5HD; 1-[(2R,6S)-6-(hydroxymethyl)morpholin-2-yl]-5-methylpyrimidine-2,4-dione; 1-((2R,6S)-6-(Hydroxymethyl)-2-morpholinyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-(6-Hydroxymethyl-morpholin-2-yl)-5-methyl-1H-pyrimidine-2,4-dione; 2,4(1H,3H)-Pyrimidinedione, 1-((2R,6S)-6-(hydroxymethyl)-2-morpholinyl)-5-methyl-; UNII-YML1Y6H5HD; SCHEMBL24420143; CS-0100784; A897935. CAS No. 179073-10-0. Molecular formula: C10H15N3O4. Mole weight: 241.24.
1-((2R,6S)-6-(Hydroxymethyl)morpholin-2-yl)pyrimidine-2,4(1H,3H)-dione, a critically important pharmaceutical component, serves as a fundamental precursor in synthesizing a spectrum of lifesaving medications, crucially employed in combating ailments like cancer, inflammation, and viral infections across varied biological settings and therapeutic contexts. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[(2R,6S)-6-(hydroxymethyl)-2-morpholinyl]-; 1-[(2R,6S)-6-(Hydroxymethyl)-2-morpholinyl]-2,4(1H,3H)-pyrimidinedione; 2,4(1H,3H)-Pyrimidinedione, 1-[6-(hydroxymethyl)-2-morpholinyl]-, (2R-cis)-; U-morpholine CH2OH. Grade: 97%. CAS No. 109205-43-8. Molecular formula: C9H13N3O4. Mole weight: 227.22.
1-((2S,3R)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 2243786-02-7. Molecular formula: C30H35N5O3. Mole weight: 513.64.
1-((2S,3R,4S,5S)-3-Chloro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione is an impurity of antiviral drug Clevudine, which is used for the treatment of Hepatitis B. Synonyms: Clevudine Impurity. Molecular formula: C10H13ClN2O5. Mole weight: 276.67.
1-((2S,3S,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione is a powerful tool in the biomedical industry, indicated for cancer, HIV and hepatitis B treatment. Its multifunctional activity includes antiviral, antitumor, and anti-inflammatory effects, with early evidence supporting a potentially revolutionary capacity as a cancer stem cell targeting therapeutic agent. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
It is a key intermediate in the synthesis of GalNAc phosphoramidite, featuring a GalNAc moiety linked to a trans-4-hydroxyprolinol (tHP) scaffold via a flexible linker. This compound is obtained through a peptide coupling reaction between GalNAc carboxylate and the tHP building block, followed by purification. It serves as a crucial precursor for the attachment of the phosphoramidite group, enabling the incorporation of GalNAc units into oligonucleotides for targeted drug delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). Synonyms: 1-Pentanone, 1-[(2S,4R)-2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-4-hydroxy-1-pyrrolidinyl]-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-; GalNAc-tHP linker; GalNAc-tHP conjugated intermediate; GalNAc-tHP precursor. CAS No. 1843261-47-1. Molecular formula: C45H56N2O14. Mole weight: 848.93.
12(S)-HHTrE
12(S)-HHTrE is a product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of human platelets. It is biosynthesized by thromboxane (TXA2) synthase from prostaglandin H2 (PGH2) concurrently with TXA2. Synonyms: 12(S)-HHT; 12-hydroxyheptadecatrienoic acid. Grade: ≥95%. CAS No. 54397-84-1. Molecular formula: C17H28O3. Mole weight: 280.4.
12(S)-HpETE
12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons6 and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex. Synonyms: 12-Hydroperoxyicosatetraenoate; (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid. Grade: ≥98%. CAS No. 71774-10-2. Molecular formula: C20H32O4. Mole weight: 336.5.
12(S)-hydroxy-16-heptadecynoic acid
12(S)-hydroxy-16-heptadecynoic acid is a mechanism-based inhibitor of cytochrome P450 ω-hydroxylase. It inhibits prostaglandin ω-hydroxylase with a Ki value of 1.8 μM. Synonyms: 16-Heptadecynoic acid,12-hydroxy-, (S)- (9CI); 12-Hydroxy-heptadec-16-ynoic acid. Grade: ≥98%. CAS No. 148019-74-3. Molecular formula: C17H30O3. Mole weight: 282.4.
1-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]ethanone is an intermediate for the synthesis of Fluphenazine, which is a phenothiazine antipsychotic, a dopaminergic antagonist and an antiviral agent. Synonyms: 1-[2-(trifluoromethyl)phenothiazin-10-yl]ethanone; 2-(Trifluoromethyl)-10-acetyl-10H-phenothiazine; 10-Acetyl-2-(trifluoromethyl)phenothiazine; 10-Acetyl-2-(trifluoromethyl)-10H-phenothiazine; Ethanone, 1-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]-; Fluphenazine Decanoate Impurity 16. Grade: ≥95%. CAS No. 1554-60-5. Molecular formula: C15H10F3NOS. Mole weight: 309.31.
13,14-Anhydro-10-desacetyl Baccatin
13,14-Anhydro-10-desacetyl Baccatin is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: Docetaxel Impurity 24. CAS No. 1217248-58-2. Molecular formula: C29H34O9. Mole weight: 526.57.
1,3:1,4-b-Glucotetraose (A)
1,3:1,4-b-Glucotetraose (A) is a carbohydrate compound with potential functionality in promoting the proliferation of beneficial gut microbiota. Synonyms: Glc1-3-Glc1-4-Glc1-4-Glc; O-β-D-Glucopyranosyl-(1→3)-O-β-D-glucopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→4)-D-glucose. CAS No. 58484-04-1. Molecular formula: C24H42O21. Mole weight: 666.58.
1,3:1,4-b-Glucotetraose (B)
1,3:1,4-b-Glucotetraose (B) is a biochemical compound mainly used in studies related to digestion and carbohydrate metabolism. Synonyms: Glc1-4-Glc1-4Glc-b1-3Glc. CAS No. 58484-02-9. Molecular formula: C24H42O21. Mole weight: 666.58.
1,3:1,4 b-Glucotetraose (C)
1,3:1,4 b-Glucotetraose (C) is a tetrasaccharide linked by β-1,3 and β-1,4 glycosidic bonds. It is often used in studying carbohydrate metabolism and has digestive enzyme functions, which can aid in understanding interventions for metabolic disorders such as diabetes. Synonyms: Glc1-4Glc1-3Glc1-4-Glc. CAS No. 103762-93-2. Molecular formula: C24H42O21. Mole weight: 666.58.
1,3:1,4 b-Glucotriose (A)
1,3:1,4 b-Glucotriose (A) is a trifecta of monosaccharide units bound in a tri-saccharide configuration. It has the functionality of an essential dietary fiber with potential applications for further research in the field of diabetes management. Synonyms: Glc1-3Glc1-4Glc. CAS No. 4467-70-3. Molecular formula: C18H32O16. Mole weight: 504.44.
1,3:1,4-b-Glucotriose (B)
1,3:1,4-b-Glucotriose (B) is a type of glucotriose found inherently in barley and oats, predominantly used in the study of starch analysis and enzymology. Synonyms: Glc-1-4Glc-1-3Glc. CAS No. 157544-59-7. Molecular formula: C18H32O16. Mole weight: 504.44.
13,14-dihydro-15-keto prostaglandin D2
13,14-dihydro-15-keto prostaglandin D2 is a metabolite of PGD2 which is formed through the 15-hydroxy PGDH pathway. It has been recently identified as a selective agonist for the DP2 receptor. Additionally, 13,14-dihydro-15-keto Prostaglandin D2 has been shown to inhibit ion flux in canine colonic mucosa preparation. Synonyms: 13,14-dihydro-15-keto PGD2; 11,15-dioxo-9S-hydroxy-5Z-prostenoic acid; (Z)-7-[(1R,2R,5S)-5-hydroxy-3-oxo-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid. Grade: ≥95%. CAS No. 59894-07-4. Molecular formula: C20H32O5. Mole weight: 352.5.
13,14-Dihydro Bimatoprost
13,14-Dihydro Bimatoprost is an impurity of Bimatoprost, which is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-N-ethyl-5-heptenamide; N-Ethyl-9-alpha,11-alpha,15R-trihydroxy-17-phenyl-18,19,20-trinor-prost-5Z-en-1-amide; Latanoprost ethyl amide; LAT-NET. Grade: 98%. CAS No. 607351-44-0. Molecular formula: C25H39NO4. Mole weight: 417.58.
13(17)a-Homodexamethasone sodium phosphate
An impurity of Dexamethasone, which is a corticosteroid medication used for inflammations. Synonyms: 9-Fluoro-11β,17,21-trihydroxy-16α-methyl-13(17)a-homopregna-1,4-diene-3,13a,20-trione 21-(dihydrogen phosphate) disodium salt. Molecular formula: C22H28FNa2O8P. Mole weight: 516.4.
1,3:2,4-Bis(O-benzylidene)-D-sorbitol
1,3:2,4-Bis(O-benzylidene)-D-sorbitol, a renown antitumor compound, is extensively utilized in the biomedical sector. Its applications span across diverse cancer types, encompassing breast, lung, and colon cancer, presenting impressive therapeutic outcomes. The compound exerts inhibitory effects on tumor cell growth through robust cytotoxic activity, rendering it an indispensable asset for cancer investigations and pharmaceutical advancements. Its utilization in cancer research and drug development is of paramount significance. Synonyms: Dibenzylidene sorbitol. CAS No. 19046-64-1. Molecular formula: C20H22O6. Mole weight: 358.39.
1-(3-((2,4-dimethylphenyl)thio)phenyl)piperazine
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well as a Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: Piperazine, 1-[3-[(2,4-dimethylphenyl)thio]phenyl]-; Vortioxetine Impurity J; Vortioxetine Impurity 07. CAS No. 2137588-68-0. Molecular formula: C18H22N2S. Mole weight: 298.45.
1,3:2,4-Di-p-methylbenzylidene sorbitol
1,3:2,4-Di-p-methylbenzylidene sorbitol is a pharmaceutical excipient. It's often employed in studying slow-release of drugs due to its ability to modify drug dissolution rates. Its heat stability and low reactivity make it ideal for controlled drug delivery systems. Synonyms: Bis(p-methylbenzylidene)sorbitol. CAS No. 54686-97-4. Molecular formula: C22H26O6. Mole weight: 386.44.
1-[[3-(2-Chlorophenyl)-2-(4-fluorophenyl)-2-oxiranyl]methyl]-1H-1,2,4-triazole is an impurity of Epoxiconazole, which is a fungicide used to control a wide range of fungal diseases. Uses: Fungicides, industrial. Synonyms: 1H-1,2,4-Triazole, 1-[[3-(2-chlorophenyl)-2-(4-fluorophenyl)-2-oxiranyl]methyl]-; 1H-1,2,4-Triazole, 1-[[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-; 1-[[3-(2-Chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-1H-1,2,4-triazole; 1-((3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole; (2RS,3SR)-1-[3-(2-chlorophenyl)-2,3-epoxy-2-(4-fluorophenyl)propyl]-1H-1,2,4-triazole. Grade: ≥95%. CAS No. 135319-73-2. Molecular formula: C17H13ClFN3O. Mole weight: 329.76.
1-[(3,3-Diphenylpropyl)methylamino]-2-methyl-2-propanol is an intermediate of Lercanidipine, which is a dihydropyridine calcium channel blocker. Uses: Lercanidipine intermediate. Synonyms: 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-ol; Lercanidipine EP Impurity E; 2,N-Dimethyl-N-(3,3-diphenylpropyl)-1-amino-2-propanol; 2-Propanol, 1-[(3,3-diphenylpropyl)methylamino]-2-methyl-; 1-(3,3-Diphenyl-N-methylpropylamino)-2-methyl-2-propanol; N,2-Dimethyl-3,3-diphenylpropylamine-2-propanol; N,2-Dimethyl-N-(3,3-diphenylpropyl)-1-amino-2-propanol. Grade: 98%. CAS No. 100442-33-9. Molecular formula: C20H27NO. Mole weight: 297.43.
13-{[(3-N-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(triethylsilyl) Baccatin III
13-{[(3-N-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(triethylsilyl) Baccatin III is one of Paclitaxel precursors. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: (4S,5R)-2,2-Dimethyl-4-phenyl-3,5-oxazolidinedicarboxylic Acid 5-[(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl] 3-(1,1-dimethylethyl) Ester; 5-{(3xi,5beta,7alpha,10beta,13alpha)-4,10-Bis(acetyloxy)-2-(benzoyloxy)-1-hydroxy-9-oxo-7-[(triethylsilyl)oxy]-5,20-epoxytax-11-en-13-yl} 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate. Grade: 98%. CAS No. 143527-71-3. Molecular formula: C54H73NO15Si. Mole weight: 1004.24.
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-6α,7α-dihydroxy Baccatin III
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-6α,7α-dihydroxy Baccatin III is one of Paclitaxel intermediates. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Molecular formula: C48H59NO16. Mole weight: 905.98.
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-6α,7β-dihydroxy Baccatin III
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-6α,7β-dihydroxy Baccatin III is one of Paclitaxel intermediates. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Molecular formula: C48H59NO16. Mole weight: 905.98.