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2'-Deoxy-5'-O-DMT-N2-isobutyryl-6-thioguanosine 3-CE phosphoramidite is a crucial component used in the synthesis of nucleic acid oligomers. This phosphoramidite is mainly employed in the biomedical industry for the production of modified DNA or RNA sequences. It enables the incorporation of the N2-isobutyryl-6-thioguanosine moiety during solid-phase synthesis. These modified oligomers find applications in studying DNA-protein interactions and developing potential therapeutics targeting diseases such as cancer and viral infections. CAS No. 125698-85-3. Molecular formula: C44H54N7O7PS. Mole weight: 855.98.
2-Deoxy-5'-O-DMT-N2-isobutyryl-8-oxoguanosine 3'-CE phosphoramidite is a valuable tool in the biomedical industry for synthesizing modified oligonucleotides. This phosphoramidite derivative facilitates the introduction of a 3'-CE modifier during DNA synthesis, enabling the study of DNA-protein interactions and the development of therapeutic oligonucleotides. Additionally, it finds applications in chemical biology research, drug discovery, and diagnostics, particularly in elucidating the role of modified nucleotides in various diseases and their potential for targeted therapy. Synonyms: 2'-Deoxy-5'-O-DMT-isobutyryl-8-oxoguanosine 3'-CE phosphoramidite; 5'-O-DMT-isobutyryl-8-oxo-2'-deoxyguanosine 3'-CE phosphoramidite. Molecular formula: C44H54N7O9P. Mole weight: 855.94.
2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine
2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine, an esteemed modified nucleoside utilized in the realm of biomedicine, showcases its noteworthy significance pertaining to targeted drug delivery and gene therapy. Its exceptional potential in selectively conveying therapeutic agents to designated cells or tissues renders it advantageous in combatting a myriad of ailments, including cancer and genetic disorders. Synonyms: 2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-D-guanosine; 5'-O-DMT-N2-isobutyryl-2'-deoxy-a-guanosine. Grades: ≥ 97% (HPLC). CAS No. 149099-40-1. Molecular formula: C35H37N5O7. Mole weight: 639.71.
2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine-3'-(4-nitrophenoxyl)butanedioate, a groundbreaking biomedicine, revolutionizes targeted drug delivery systems to combat diverse ailments. Through conjugation with specialized medications, it facilitates site-specific drug release, heightening their effectiveness while mitigating general toxicities.
2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-H phosphonate triethylammonium salt
2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-H phosphonate triethylammonium salt, an innovative biomedical product, holds immense potential in the therapeutic landscape. Extensively utilized for combating diverse ailments, this compound intricately disrupts viral replication, thereby showcasing remarkable antiviral activity. By precisely targeting specific infections, it serves as a formidable antiviral drug, revolutionizing the pursuit of efficacious therapies. Crafted with scientific precision, this product paves the way for groundbreaking advancements in the field of medicine. Synonyms: 2'-Deoxy-5'-O-DMT-N2-isobutyryl-D-guanosine 3'-H phosphonate triethylammonium salt; 5'-O-DMT-N2-isobutyryl-2'-deoxyguanosine 3'-H phosphonate triethylammonium salt. CAS No. 181269-06-7. Molecular formula: C35H37N5O9P. Mole weight: 804.89.
2'-Deoxy-5'-O-DMT-N2-isobutyryl-guanosine-3'-lcaa-CPG, a highly significant compound extensively employed in the realm of biomedicine due to its invaluable contributions towards drug development. With paramount relevance in the synthesis of oligonucleotides, this product finds application in therapies designed specifically for the combat against malignant ailments like cancer and viral infections. Synonyms: DMT-dG-NiBu-lcaa-CPG.
2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-Me phosphonamidite, a crucial chemical entity in the realm of biomedicine, assumes a pivotal role. This phosphonamidite derivative finds extensive utility in the synthesis of customized oligonucleotides for cutting-edge biomedical investigations. Renowned for its exquisite potential, it facilitates the precise embellishment of nucleotides, catalyzing the development of nucleic acid-centric therapeutics directing their sights towards a myriad of pharmacotherapeutic interventions including oncological ailments, viral pathologies, and hereditary abnormalities. Synonyms: 5'-(4,4'-Dimethoxytrityl)-N-isobutyryl-2'-deoxyguanosine, 3'-[methyl-(N,N-diisopropyl)]-phosphonamidite; iBu-dG-Me Phosphonamidite. Molecular formula: C42H53N6O7P. Mole weight: 784.88.
2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-thiophosphoramidite, an extensively utilized compound within the biomedical sector, displays promise for investigating nucleotide modifications and their influence on gene expression. Additionally, its plausible therapeutic applications have garnered attention, although additional research is imperative. Notably, this academically significant product holds potential for exploring disease treatment and condition amelioration. Synonyms: 2'-Deoxy-5'-dimethoxytrityl-N-isobutyryl-guanosine-3'-[(B-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite. Molecular formula: C48H53N6O8PS2. Mole weight: 937.08.
2'-Deoxy-5'-O-DMT-N2-isopropylguanosine
2'-Deoxy-5'-O-DMT-N2-isopropylguanosine is an indispensable compound in nucleic acid synthesis, emerging as a biomedical innovation. Unveiling its transformative potential, this modified guanosine variant proves instrumental in unravelling the intricate mechanisms underlying multifaceted ailments, including viral infections and cancer. Synonyms: 2'-Deoxy-5'-O-DMT-N2-isopropyl-D-guanosine; 5'-O-DMT-N2-isopropyl-2'-deoxyguanosine. CAS No. 863910-15-0. Molecular formula: C34H37N5O6. Mole weight: 611.70.
2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite is a crucial compound used in the synthesis of oligonucleotides for biomedical applications. It serves as a phosphoramidite building block during solid-phase DNA synthesis, enabling the incorporation of N2-isopropylguanosine modifications. These modified oligonucleotides find use in research related to mRNA therapeutics, gene therapy, and antisense technology, enhancing their efficacy in treating various diseases like cancer, genetic disorders, and viral infections. Synonyms: 2'-Deoxy-5'-O-DMT-N2-isopropyl-D-guanosine 3'-CE phosphoramidite; 5'-O-DMT-N2-isopropyl-2'-deoxyguanosine 3'-CE phosphoramidite. Molecular formula: C43H54N7O7P. Mole weight: 811.93.
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine, a remarkable compound hailed in biomedical research, exhibits promise in combating specific ailments. The intricate nature of its chemical composition renders it invaluable for the advancement of targeted pharmaceuticals designed to address diverse maladies. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-N4-[(9H-fluoren-9-ylmethoxy)carbonyl]-5-methylcytidine; (9H-Fluoren-9-yl)methyl (1- ( (2R, 4S, 5R)-5- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-methyl-2-oxo-1, 2-dihydropyrimidin-4-yl)carbamate; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-5-methyl-cytidine. Grades: ≥95%. CAS No. 176755-86-5. Molecular formula: C46H43N3O8. Mole weight: 765.85.
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite, an indispensable biochemical reagent, finds extensive application in the synthesis of modified nucleosides for groundbreaking biomedical research. Its usage is pivotal in the quest for novel drugs and therapies that target specific ailments, including cancer and viral infections. Additionally, this product's significance permeates the realm of nucleic acid chemistry, enabling researchers to delve into the intricacies of DNA and RNA modifications, thereby augmenting drug effectiveness and improving disease detection techniques. Synonyms: BP-40031; 5'-O-DMTr-N4-Fmoc-5-Me-dC-phosphoramidite; (9H-Fluoren-9-yl)methyl (1- ( (2R, 4S, 5R) -5- ( (bis (4-methoxyphenyl) (phenyl) methoxy) methyl) -4- ( ( (2-cyanoethoxy) (diisopropylamino) phosphino) oxy) tetrahydrofuran-2-yl) -5-methyl-2-oxo-1, 2-dihydropyrimidin-4-yl) carbamate; (9H-Fluoren-9-yl) methyl (1- ( (2R, 4S, 5R) -5- ( (bis (4-methoxyphenyl) (phenyl) methoxy) methyl) -4- ( ( (2-cyanoethoxy) (diisopropylamino) phosphino) oxy) tetrahydrofuran-2-yl) -5-methyl-2-oxo-1, 2-dihydropyrimidin-4-yl) carbamate; 9H-Fluoren-9-ylmethyl N-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]carbamate. CAS No. 176755-87-6. Molecular formula: C55H60N5O9P. Mole weight: 966.1.
2'-Deoxy-5'-O-DMT-N4-isobutyryl-5-methylcytidine
2'-Deoxy-5'-O-DMT-N4-isobutyryl-5-methylcytidine, a groundbreaking biomedical compound, holds immense significance in the advancement of focused therapeutics for diverse ailments. With its pivotal role in combating cancers, viral infections, and genetic disorders, this product intertwines with cutting-edge biomedical research. Its distinctive architecture and characteristics grant scientists an invaluable instrument to unravel innovative therapeutic modalities and enhance patient prognosis. Synonyms: 5'-DMT-N4-ibu-5-Me-dC; 5'-O-(4,4'-Dimethoxytrityl)-N4-Isobutyryl-5-Methyl-2'-deoxycytidine; Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-N-(2-methyl-1-oxopropyl)-; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyryl-5-methylcytidine. Grades: ≥97% by HPLC. CAS No. 176755-84-3. Molecular formula: C35H39N3O7. Mole weight: 613.71.
2'-Deoxy-5'-O-DMT-N6-Fmoc-adenosine 3'CE-phosphoramidite, a highly coveted resource in the realm of biomedical research, serves as a catalyst for generating customized nucleic acid structures. Delving into unexplored terrains, this versatile entity facilitates the infusion of N6-Fmoc-adenosine adaptations into oligonucleotides, enabling precise exploration of modified nucleic acids and their intricate interplay with designated proteins or enzymes. CAS No. 109420-86-2.
2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine
2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine, a highly potent chemical compound, holds immense significance in the field of biomedicine. As a pivotal drug intermediate, it aids in the treatment of a myriad of diseases. Moreover, its utilization in the synthesis of nucleoside analogs and nucleic acids drives advancements in antiviral, anticancer, and antifungal medications. Synonyms: 5'-O-DMT-N6-iBu-dA; Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)-; 5'-O-DMT-N6-isobutyryl-2'-deoxyadenosine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyryladenosine. Grades: ≥98% by HPLC. CAS No. 190834-10-7. Molecular formula: C35H37N5O6. Mole weight: 623.72.
2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine 3'-CE phosphoramidite, also known as 2'-deoxy-5'-O-dimethoxytrityl-N6-isobutyryladenosine 3'-CE phosphoramidite, has primary application lies in the synthesis of altered forms of RNA and DNA molecules. By incorporating this phosphoramidite into the structure of nucleic acids, researchers are empowered to devise targeted interventions against various diseases, such as cancer and genetic disorders. Molecular formula: C44H54N7O7P. Mole weight: 823.94.
2'-Deoxy-5'-O-DMT-N6-methyl-8-oxoadenosine 3'-CE phosphoramidite is a crucial component used in the biomedical industry for synthesizing oligonucleotides. This phosphoramidite derivative aids in the introduction of 2'-Deoxy-5'-O-DMT-N6-methyl-8-oxoadenosine modifications into nucleic acids during solid-phase DNA synthesis. These customized nucleic acid sequences find application in various research fields, including medicinal chemistry, genetic engineering, and drug discovery, enabling the development of targeted therapies for specific diseases. Synonyms: 2'-Deoxy-5'-O-DMT-N6-methyl-8-oxo-D-adenosine 3'-CE phosphoramidite; 5'-O-DMT-N6-methyl-8-oxo-2'-deoxyadenosine 3'-CE phosphoroamidite. Molecular formula: C41H50N7O7P. Mole weight: 767.85.
2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine
2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine is a highly potent compound utilized extensively within the biomedical sector, notably employed in discerning drug discovery and specialized therapeutic interventions. This instrumental entity boasts an intricate composition and inherent characteristics, rendering it invaluable for investigating the intricate functionality of adenosine receptors and their prospective manipulation in mitigating specific pathological conditions. Synonyms: 2'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-N6-phenoxyacetyladenosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(2-phenoxyacetyl)adenosine; 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyl-D-adenosine; 5'-ODMT-N6-phenoxyacetyl-2'-deoxyadenosine; N- (9- ( (2R, 4S, 5R)-5- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)-2-phenoxyacetamide; Pheac-Dmt-Deoxyadenosine. Grades: ≥95%. CAS No. 110522-82-2. Molecular formula: C39H37N5O7. Mole weight: 687.74.
2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-Me phosphoramidite, a highly regarded biochemical agent, has garnered considerable attention in the realm of biomedicine research. This extraordinary compound serves as an instrumental tool for facilitating DNA synthesis and modification, offering unprecedented opportunities for investigating intricate cellular mechanisms and disease etiology. By employing its unique modifications, researchers can delve into a myriad of applications, encompassing the development of precision drug delivery systems and the conception of revolutionary gene-based therapies targeting a wide spectrum of ailments, such as cancer and hereditary disorders. Synonyms: Pac-dA-Me Phosphoramidite; 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyl-D-adenosine 3'-Me phosphoramidite; 5'-O-DMT-N6-phenoxyacetyl-2'-deoxyadenosine 3'-Me phosphoramidite. Molecular formula: C46H53N6O8P. Mole weight: 848.94.
2'-Deoxy-5'-O-DMT-uridine 3'-succinyl CPG
2'-Deoxy-5'-O-DMT-uridine 3'-succinyl CPG is a crucial tool in the biomedical industry for the development of nucleotide-based therapies. It serves as a solid support matrix for the synthesis of nucleic acids, including antisense oligonucleotides and siRNA, targeting a wide range of diseases such as cancer, genetic disorders, and viral infections. This product facilitates the efficient and controlled synthesis of customized nucleotide sequences, aiding researchers in the discovery and advancement of novel medical interventions.
2'-Deoxy-5'-O-DMT-uridine succinyl 3'-CPG
2'-Deoxy-5'-O-methyl-uridine
2'-Deoxy-5'-O-methyl-uridine is an intermediate in synthesizing 5'O,6-Cyclo-dihydro-2',2'-difluoro-2'-deoxyuridine, which is an impurity (a product of degradation) of Gemcitabine Hydrochloride, an antineoplastic agent. Synonyms: 1-((2R,4S,5R)-4-Hydroxy-5-(methoxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. CAS No. 134785-27-6. Molecular formula: C10H14N2O5. Mole weight: 242.23.
2'-Deoxy-5'-O-pixylinosine
2'-Deoxy-5'-O-pixylinosine is an indispensable and extensively utilized compound in the realm of biomedicine. It assumes a pivotal function in the advancement of antiviral medications, predominantly in the management of viral afflictions like HIV and hepatitis. This compound displays formidable inhibitory consequences on viral replication, thereby embodying a hopeful contender for the formulation of novel therapeutic interventions. Synonyms: 2-Deoxy-5'-O-pixyl-D-inosine; 5'-O-Pixyl-2'-deoxyinosine. Molecular formula: C30H26N4O4. Mole weight: 506.57.
2'-Deoxy-5'-O-pixyluridine
2'-Deoxy-5'-O-pixyluridine is a highly potent nucleoside analogue, 2'-Deoxy-5'-O-pixyluridine, defing viral replication by seamlessly integrating with viral DNA. Consequently, chain termination transpires, effectively impeding viral proliferation and curtailing its rampant growth. Synonyms: 2'-Deoxy-5'-O-pixyl-D-uridine; 5'-O-Pixyl-2'-deoxyuridine. Molecular formula: C28H24N2O6. Mole weight: 484.51.
2'-Deoxy-5'-O-tritylinosine 3'-CE phosphoramidite
2'-Deoxy-5'-O-tritylinosine 3'-CE phosphoramidite is a vital component in the synthesis of oligonucleotides used in biomedicine. It plays a crucial role in the development of drugs targeting specific diseases like cancer, genetic disorders, and viral infections. This highly pure and efficient phosphoramidite enables accurate and controlled incorporation of modified nucleotides during the oligonucleotide synthesis process, facilitating research and advancements in the biomedical industry. Synonyms: 2'-Deoxy-5'-O-trityl-D-inosine 3'-CE phosphoramidite; 5'-O-Trityl-2'-deoxyinosine 3'-CE phosphoramidite. Molecular formula: C38H43N6O5P. Mole weight: 694.78.
2'-Deoxy-5'-O-trityluridine 3'-CE phosphoramidite
2'-Deoxy-5'-O-trityluridine 3'-CE phosphoramidite, a remarkable and indispensible entity within the domain of biomedicine, serves as a fundamental building block. In the realm of oligonucleotide synthesis, it finds widespread application, spanning the vast landscape of viral infection and genetic afflictions amelioration. Armed with its prowess, this compound empowers scientists to undertake pioneering investigations, unraveling uncharted therapeutic pathways and forging tailored pharmacological agents for precise ailment intervention. Synonyms: 5'-O-Trityl-D-uridine 3'-CE phosphoramidite. Molecular formula: C37H43N4O6P. Mole weight: 670.75.
2'-Deoxy-5-trifluoromethyluridine-5'-monophosphate is a vital compound in the biomedical industry. It is used in the development of antiviral drugs, particularly those aimed at treating RNA-based viruses such as HIV and hepatitis C. Synonyms: α,?α,?α-Trifluoro-5'-thymidylic acid; Trifluridine-5-phosphate; 5-Trifluoromethyl-2'-deoxyuridylic acid. CAS No. 345-02-8. Molecular formula: C10H12F3N2O8P. Mole weight: 376.18.
2'-Deoxy-6-hydroxycytidine
2'-Deoxy-6-hydroxycytidine, a highly esteemed compound extensively employed in the biomedical sector, holds immense value. It showcases remarkable antiviral attributes, thereby vitalizing the progression of therapeutic interventions against numerous viral ailments, exemplifying hepatitis C. Through the inhibition of viral replication, this compound emerges as a promising contender for the creation of efficacious antiviral pharmaceuticals. Unearth the depths of its biomedical applications and envisage its profound potential in the combat against viral afflictions. Synonyms: 6-Amino-3-(2-deoxy-b-D-erythro-pentofuranosyl)?-uracil. CAS No. 23205-74-5. Molecular formula: C9H13N3O5. Mole weight: 243.22.
2'-Deoxy-6-methylthioguanosine
2'-Deoxy-6-methylthioguanosine is a robust nucleoside analogue with remarkable properties, serving as a pivotal compound in the realm of biomedical research and pharmaceutical advancements. Demonstrating profound antiviral capabilities against hepatitis viruses, it efficaciously obstructs their replication. Synonyms: 9H-Purin-2-amine, hemihydrate. Grades: ≥ 98% (HPLC). CAS No. 37113-42-1. Molecular formula: C11H15N5O3S. Mole weight: 297.33.
2'-Deoxy-6N-DMF-5'-O-DMT-adenosine
2'-Deoxy-6N-DMF-5'-O-DMT-adenosine, an essential biomolecular entity, emerges as a vital protagonist within the biomedical field. Acting as a pivotal constituent during the intricate synthesis of nucleic acids and DNA, this compound assumes a paramount role in the pursuit of therapeutic breakthroughs for an array of ailments such as cancer, viral infections, and genetic anomalies. With its unparalleled structural complexity and inherent characteristics, 2'-Deoxy-6N-DMF-5'-O-DMT-adenosine propels the frontier of biomedicine, fostering progressive inquiry and facilitating revolutionary treatment modalities. Synonyms: 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-N-[(dimethylamino)?methylene]?-adenosine. Grades: ≥ 98% (HPLC). CAS No. 17331-20-3. Molecular formula: C34H36N6O5. Mole weight: 608.69.
2'-Deoxy-6-thioguanosine-5'-monophosphate
2'-Deoxy-6-thioguanosine-5'-monophosphate is an innovative pharmaceutical entity, exquisitely designed for unveiling remarkable antiviral potency, assiduously directing its action towards impeding the pernicious propagation of RNA viruses. Deploying its inhibitory prowess upon viral enzyme activity, it efficaciously curtails the abhorrent virus's proclivity to proliferate, ensuing in a substantial amelioration of both the intensity and duration of the affliction. Synonyms: 2'-Deoxy-6-thio-5'-guanylic acid. CAS No. 15303-00-1. Molecular formula: C10H14N5O6PS. Mole weight: 363.29.
2'-Deoxy-7-deazaisoguanosine triphosphate
2'-Deoxy-7-deazaisoguanosine triphosphate, a paramount compound widely employed in the biomedical arena, serves as a fundamental constituent for DNA synthesis. Its applications extend to the treatment of select viral infections and genetic disorders, targeting distinct pathways with great efficacy. Its intricate mechanism of operation renders it indispensable in the realm of pharmaceutical advancement, addressing and ameliorating pertinent afflictions. Synonyms: 4-Amino-7-[2-deoxy-5-O-[hydroxy[[hydroxy (ph?osphonooxy) ?phosphinyl]?oxy]?phosphinyl]?-b-D-erythro-pentofuranosyl]?-1, ?7-dihydro-2H-pyrrolo[2, ?3-d]?pyrimidin-2-one. CAS No. 151520-86-4. Molecular formula: C11H17N4O13P3. Mole weight: 506.19.
2'-Deoxy-8-(1-pyrenylamino)guanosine
2'-Deoxy-8-(1-pyrenylamino)guanosine is used for gene mutations, oxidative DNA damage treatment and DNA adduct formation. Synonyms: 1-Aminopyrene-N-(2'-deoxyguanosin-8-yl). CAS No. 85989-43-1. Molecular formula: C26H22N6O4. Mole weight: 482.49.
2'-Deoxy-8-[[2-(1H-imidazol-4-yl)ethyl]amino]adenosine 5'-(Tetrahydrogen Triphosphate) is a chemically modified nucleotide that can be used in in-vitro selection. CAS No. 233758-46-8. Molecular formula: C15H23N8O12P3. Mole weight: 600.31.
2'-Deoxy-8-[(2-hydroxyethyl)thio]-adenosine
2'-Deoxy-8-[(2-hydroxyethyl)thio]-adenosine is an intermediate in the synthesis of 8-Oxo-2'-deoxyadenosine. 8-Oxo-2'-deoxyadenosine is the first example of a native DNA lesion that stabilizes human telomeric G-quadruplex DNA. Synonyms: (2R,3S,5R)-5-(6-Amino-8-((2-hydroxyethyl)thio)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol. CAS No. 876380-66-4. Molecular formula: C12H17N5O4S. Mole weight: 327.36.
2'-Deoxy-8-methoxyadenosine
2'-Deoxy-8-methoxyadenosine, a renowned compound in the field of biomedicine, emerges as a substantial candidate for combating specific ailments. Its applicability extends to the synthesis of antiviral medications, exhibiting efficacy against formidable viruses like hepatitis C and HIV. Moreover, this compound displays encouraging results in addressing diverse viral infections, thereby establishing itself as a formidable weapon against the relentless battle of infectious diseases. Synonyms: 8-methoxy-2'-deoxy-adenosine; Adenosine, 2'-deoxy-8-methoxy-; (2R,3S,5R)-5-(6-amino-8-methoxy-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol. Grades: ≥95%. CAS No. 17318-17-1. Molecular formula: C11H15N5O4. Mole weight: 281.27.
2'-Deoxy-8-methylamino-adenosine
2'-Deoxy-8-methylamino-adenosine, a formidable and widely employed medicinal compound in the biomedical sphere, takes the spotlight. Within the realm of therapeutic potential, this extraordinary product unveils its prowess, rendering it a game-changer in the fight against diverse maladies, encompassing cancer and viral afflictions alike. Synonyms: 8-Methylamino-2'-deoxy-adenosine; Adenosine, 2'-deoxy-8-(methylamino)-. Grades: ≥95%. CAS No. 13389-10-1. Molecular formula: C11H16N6O3. Mole weight: 280.28.
2'-Deoxy-8-methylthio-adenosine
2'-Deoxy-8-methylthio-adenosine, a vital biomedical component, exhibits remarkable potential in combating various malignancies, including leukemia and solid tumors. By impeding the expansion of malignant cells, it acts as an effective anti-cancer agent. Elucidating its intricate mode of action, this captivating biomolecule interferes with quintessential cellular mechanisms crucial for uncontrolled tumor proliferation. Synonyms: 8-(Methylthio)-2'-deoxyadenosine; 2'-Deoxy-8-(methylsulfanyl)adenosine; Adenosine, 2'-deoxy-8-(methylthio)-; (2R,3S,5R)-5-(6-amino-8-(methylthio)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol. Grades: ≥95%. CAS No. 29836-02-0. Molecular formula: C11H15N5O3S. Mole weight: 297.33.
2'-Deoxy-8-methylthio-guanosine
2'-Deoxy-8-methylthio-guanosine, known for its remarkable antiviral attributes, holds great significance in the biomedical realm. Its utilization prevails as a potent therapeutic solution against various viral ailments such as hepatitis C and herpes simplex. This compound adeptly hampers viral replication by precisely targeting pivotal enzymes involved in the intricate viral life cycle. Evidently, the profound mechanism of action it possesses renders this compound an indispensable asset for rigorous viral infection investigations and therapeutic interventions. Synonyms: 8-methylthio-2'-deoxyguanosine; Guanosine, 2'-deoxy-8-(methylthio)-. Grades: ≥95%. CAS No. 157946-92-4. Molecular formula: C11H15N5O4S. Mole weight: 313.33.
2'-Deoxy-8-oxo-6-thioguanosine 5'-triphosphate
2'-Deoxy-8-oxo-6-thioguanosine 5'-triphosphate, a highly indispensable constituent in biomedical research, exhibits paramount significance as a substrate for enzymatic investigations and nucleotide analysis. Embellishing explorations into DNA damage response mechanisms, antiviral medication advancement, and the scrutiny of cancerous and other ailment-causing genetic mutations, this modified guanosine triphosphate analogue harbors substantial potential. Its unparalleled configuration and characteristic attributes render it an irreplaceable asset in the realm of comprehending nucleotide modifications and their repercussions on manifold cellular processes. Molecular formula: C10H16N5O13P3S. Mole weight: 539.24.
2'-Deoxy-a-cytidine
2'-Deoxy-a-cytidine is a vital compound in biomedicine used for various applications. Its role lies in nucleic acid research, where it acting as a precursor in the synthesis of DNA. Additionally, it is utilized for studying the antiviral properties of nucleoside analogs against viral diseases. This compound plays a significant role in the development of therapeutics and understanding diseases at the molecular level. Synonyms: 2'-Deoxy-a-D-cytidine. Grades: ≥ 98% (HPLC). CAS No. 4449-40-5. Molecular formula: C9H13N3O4. Mole weight: 227.22.
2'-Deoxyadenosine 3'-Monophosphate 5'-Triphosphate Triethylamine Salt
2'-Deoxyadenosine 3'-Monophosphate 5'-Triphosphate is a derivative of 2'-Deoxyadenosine which is anti-hepatitis C virus agents in the synthesis of 5'-modified 2'-deoxyadenosine analogues. Synonyms: 2'-Deoxyadenosine 5'-Triphosphate 3'-Phosphate Triethylamine Salt. Molecular formula: C10H19N5O15P4 xC6H15N. Mole weight: 573.18.
2'-Deoxyadenosine 3'-O-L-valinyl ester
2'-Deoxyadenosine-5'-[(a,b)-methyleno]triphosphate sodium salt
2'-Deoxyadenosine-5'-[(a,b)-methyleno]triphosphate sodium salt, commonly utilized in biomedicine for DNA synthesis and sequencing, serves as an invaluable reagent. With its ability to act as a precursor molecule for the integration of altered nucleotides into DNA strands, it greatly aids in the examination of DNA replication, repair, and transcription mechanisms. This remarkable product also contributes significantly to the advancement of therapeutic approaches targeting viral infections, cancer management, and genetic disorders. Synonyms: dApCpp; dAMPCPP. Grades: ≥ 95% (HPLC). Molecular formula: C11H18N5O11P3·xNa. Mole weight: 489.21 (free acid).
2'-Deoxyadenosine 5'-a-thiotriphosphate sodium salt
2'-Deoxyadenosine 5'-a-thiotriphosphate sodium salt is a crucial tool extensively used in the biomedical industry for various research purposes. It serves as a modified nucleotide analog used in DNA sequencing, structural analyses, and enzyme kinetics studies. Additionally, it finds utility in developing antiviral drugs targeting specific viral RNA or DNA polymerases. Molecular formula: C10H12N5Na3O12P3S. Mole weight: 588.18.
2'-Deoxyadenosine-5'-carboxylic acid
2'-Deoxyadenosine-5'-carboxylic acid is an indispensable biochemical compound extensively employed in the biomedical sector possessing profound implications in the synthesis of nucleotides and nucleic acids. It emanates as an invaluable compound in studying genetic disorders, viral infections and cancer. Synonyms: 1-(6-Amino-9H-purin-9-yl)?-1,?2-dideoxy-b-D-erythro-pentofuranuronic acid. CAS No. 4603-70-7. Molecular formula: C10H11N5O4. Mole weight: 265.23.
2'-Deoxyadenosine-5'-O-(1-Boranotriphosphate)
2'-Deoxyadenosine-5'-O-(1-Boranotriphosphate), a pharmaceutical compound, has been specifically developed to tackle certain types of cancer by inhibiting enzymes involved in DNA replication and repair. Its efficacy is heightened because, by suppressing vital components in the DNA synthesis pathway, the drug hinders the rapid growth and multiplication of cancer cells. This makes it a potent antidote to a variety of hematological and solid tumor cancers, possibly offering a new form of treatment to doctors fighting such scourges. Synonyms: 1-Borano-dATP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H18N5O11P3B. Mole weight: 488.00.
2'-Deoxyadenosine-5'-O-(1-Thiotriphosphate)
2'-Deoxyadenosine-5'-O-(1-Thiotriphosphate) - a specialized nucleotide - is typically employed in biochemical assays that evaluate the functioning of enzymes, including kinases and GTPases. Its inclusion in such assays is aimed at exploring the intricate mechanics of protein phosphorylation and nucleotide exchange in the aforementioned enzymes. Synonyms: Alpha Thiol dATP; 1-Thio-dATP. Grades: ≥95% by AX-HPLC. Molecular formula: C10H16N5O11P3S. Mole weight: 507.25.
2'-Deoxyadenosine-5'-triphosphate dilithium salt
With its indispensability in the biomedical sector, 2'-Deoxyadenosine-5'-triphosphate dilithium salt assumes a pivotal role as a reagent. It finds extensive application in enzymatic labeling reactions and DNA sequencing, serving as an imperative substrate for DNA polymerases. Within the realm of genetic and nucleotide modifications research, this product assumes paramount significance, while concurrently contributing to the advancement of antiviral therapeutics and drugs targeting the fundamental processes of DNA replication. Molecular formula: C10H13N5O12P3·2Li. Mole weight: 502.04.
2'-Deoxyadenosine Monohydrate
2'-Deoxyadenosine Monohydrate is used in the synthesis of 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents. Synonyms: 2'-Deoxy-β-D-adenosine Monohydrate; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)adenine; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-amine Hydrate; Adenine Deoxyribonucleoside Hydrate; Adenine Deoxyribose Hydrate; Adenyldeoxyriboside Hydrate; Deoxyadenosine Hydrate; Desoxyadenosine Hydrate; NSC 141848; NSC 143510; NSC 83258; dA; 1-(6-Amino-9H-purin-9-yl)-1,2-dideoxy-β-D-ribofuranose Hydrate; 2-Deoxyadenine-9-β-D-erythro-pento-furanoside Hydrate. Grades: 98 %. CAS No. 16373-93-6. Molecular formula: C10H15N5O4. Mole weight: 269.26.
2'-Deoxyadenylyl-(3'-5')-2'-deoxyadenosine
2'-Deoxyadenylyl-(3'-5')-2'-deoxyadenosine, a critical intermediate in nucleic acid synthesis and repair, is known for its pivotal role in repairing damaged DNA caused by cancer chemotherapeutic drugs by reversing DNA chain breaks via enzymatic utilization. This compound's potential as a treatment for DNA damage-associated diseases has also been subject to considerable scientific scrutiny. Synonyms: dApdA DNA Dinucleotide (5'-3'). Grades: ≥95% by AX-HPLC. CAS No. 23339-45-9. Molecular formula: C20H25N10O8P. Mole weight: 564.50.
2'-Deoxy-a-uridine
2'-Deoxy-a-uridine is a remarkable nucleoside analogue emerging as a pivotal player in research of combating viral infections, specifically targeting hepatitis B and C. Its indisputable significance lies in its remarkable ability to impede viral RNA replication by effectively interfering with the reverse transcriptase enzyme. Synonyms: 2'-Deoxy-a-D-uridine. Grades: ≥ 98% (HPLC). CAS No. 41546-05-8. Molecular formula: C9H12N2O5. Mole weight: 228.21.
2'-Deoxy-β-L-adenosine
A useful synthon for modified oligodeoxyribonucleotides. Uses: A useful synthon for modified oligodeoxyribonucleotides. Synonyms: 9-(2-Deoxy-β-L-erythro-pentofuranosyl)-9H-purin-6-amine. Grades: 95%. CAS No. 14365-45-8. Molecular formula: C10H13N5O3. Mole weight: 251.24.
2'-Deoxycytidine
A deoxyribonucleoside as Eg5 kinesin modulator with antiproliferative and apoptosis-inducing activity. Synonyms: deoxycytidine; dCYD. Grades: ≥ 98 % by HPLC. CAS No. 951-77-9. Molecular formula: C9H13N3O4. Mole weight: 227.22.
2'-Deoxycytidine-3'-monophosphate disodium salt
2'-Deoxycytidine-3'-monophosphate disodium salt, a nucleotide analog frequently applied in anticancer treatment, has exhibited high effectiveness due to its exceptional ability to impede DNA synthesis, either used alone or combined with other chemotherapeutic agents. Additionally, this product has found popular use in DNA sequencing and PCR amplification, attesting to its versatility and promise in the field of science and medicine. Synonyms: disodium (2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl hydrogenphosphate; 3'-Cytidylic acid, 2'-deoxy-, disodium salt; 2'-Deoxy-3'-cytidylic acid disodium salt; 3'-dCMP sodium salt; 2'-deoxy-3'-CMP·Na2; Disodium 2'-deoxy-3'-O-phosphonatocytidine. Grades: ≥97% by HPLC. CAS No. 102814-05-1. Molecular formula: C9H12N3Na2O7P. Mole weight: 351.16.
2'-Deoxycytidine-3'-monophosphate monosodium salt
2'-Deoxycytidine-3'-monophosphate monosodium salt, a nucleotide analog utilized in DNA synthesis, is known for its activity against herpes simplex virus and cytomegalovirus. It is frequently employed in enzymatic assays as a substrate to investigate DNA replication and repair mechanisms. With its broad therapeutic potential and versatile biochemical properties, this compound has drawn significant attention in scientific research. Synonyms: sodium (2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl hydrogenphosphate; 3'-Cytidylic acid, 2'-deoxy-, sodium salt; 2'-Deoxy-3'-cytidylic acid sodium salt; 3'-dCMP sodium salt; 2'-deoxy-3'-CMP·Na; Sodium 2'-deoxy-3'-O-(hydroxyphosphinato)cytidine. Grades: ≥97% by HPLC. Molecular formula: C9H13N3NaO7P. Mole weight: 329.18.
2'-Deoxycytidine-5-carboxylic acid, sodium salt
2'-Deoxycytidine-5-carboxylic acid, sodium salt, an indispensable biomedical compound, emerges as a critical entity within the scientific realm. Renowned for its prowess, this product assumes a pivotal role in the proliferation of antiviral therapeutics, effectively combating an array of viral afflictions. Moreover, its efficacy extends to curbing the malignancy of specific cancer variants, impeding the rapid proliferation of malignant cells. Synonyms: 4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidine-5-carboxylate. Grades: 95%. CAS No. 1009808-62-1. Molecular formula: C10H12N3NaO6. Mole weight: 293.21.
2'-Deoxycytidine-5-carboxylic Acid Sodium Salt (>85%)
2'-Deoxycytidine-5-carboxylic Acid Sodium Salt, is derivative of 5-Hydroxy-2'-deoxycytidine, which have been used as a substrate for uracil DNA N-glycosylase and has been used to study the oxidation of DNA due to exposure to reactive oxygen species. Synonyms: 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,2-dihydro-2-oxo-5-pyrimidinecarboxylic Acid Sodium Salt. Grades: 85%. Molecular formula: C10H12N3NaO6. Mole weight: 293.21.
2'-Deoxycytidine-5'-diphosphate
2'-Deoxycytidine-5'-diphosphate is a pivotal compound extensively employed in the biomedical field, serving as an indispensable entity pertaining to cellular metabolism, predominantly concerning DNA research and development and repair. This compound primarily engages in the research of diverse ailments correlated with DNA impairment, encompassing malignancies, hereditary anomalies, and viral invasions. Synonyms: dCDP; Deoxycytidine diphosphate; 2'-deoxycytidine diphosphate; Deoxy-CDP; 2'-deoxycytidine 5'-(trihydrogen diphosphate); delta-1beta-Ribofuranosylcytosine diphosphate; ((2R,3S,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate; 4-amino-1-[2-deoxy-5-O-[hydroxy(phosphonooxy)phosphinyl]-beta-D-erythro-pentofuranosyl]-2(1H)-pyrimidinone; 2'-Deoxy-CDP. Grades: ≥98% by HPLC. CAS No. 800-73-7. Molecular formula: C9H15N3O10P2. Mole weight: 387.18.
2'-Deoxycytidine 5'-Diphosphate Sodium Salt Hydrate
A phosphorylated metabolite of the deoxyribonucleoside 2'-Deoxycytidine. A constituent of Deoxyribonucleic acid. Molecular formula: C9H15N3O10P2 XH2O XNa. Mole weight: 387.18.
2'-Deoxycytidine-5'-monophosphate
2'-Deoxycytidine-5'-monophosphate is a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase to form dCDP during nucleic acid synthesis. Synonyms: dCMP; deoxycytidylic acid; deoxycytidine monophosphate. Grades: 95%. CAS No. 1032-65-1. Molecular formula: C9H14N3O7P. Mole weight: 307.20.
2'-Deoxycytidine-5'-O-(1-Boranotriphosphate)
2'-Deoxycytidine-5'-O-(1-Boranotriphosphate) is known for its intricate structure and critical role propeling the progress of nucleic acid-based pharmaceuticals. Synonyms: 1-Borano-dCTP. Grades: ≥90% by AX-HPLC. Molecular formula: C9H18N3O12P3B. Mole weight: 463.90.
2'-Deoxycytidine-5'-O-(1-Thiotriphosphate)
2'-Deoxycytidine-5'-O-(1-Thiotriphosphate) - a prime asset within the domain of pharmaceutical research. This compound is amply exploited in enzymatic assays, aimed at comprehending the intricacies of DNA-dependent RNA and DNA polymerases during both replication and transcription. Its merit notably extends towards the development of antiviral medications targeted at ameliorating the progression of viral infections inclusive of HIV. Synonyms: Alpha Thiol dCTP; 1-Thio-dCTP; alpha-Phosphorothioate-modified dctp. Grades: ≥95% by AX-HPLC. Molecular formula: C9H16N3O12P3S. Mole weight: 483.23.
2'-Deoxycytidylyl-(3'-5')-thymidine
2'-Deoxycytidylyl-(3'-5')-thymidine, a nucleotide analogue, holds potential as an antiviral agent against both HIV-1 and HIV-2. By inhibiting reverse transcriptase, viral replication is impeded, thus curbing infection. Research suggests that it may also be efficacious in combating cancerous cells. Synonyms: dCpdT DNA Dinucleotide (5'-3'); 2'-Dcpt. Grades: ≥95% by AX-HPLC. CAS No. 4829-64-5. Molecular formula: C19H26N5O11P. Mole weight: 531.40.
2'-Deoxyguanosine 3'-Monophosphate 5'-Triphosphate Triethylamine Salt
Deoxyguanosine 3'-Monophosphate 5'-Triphosphate is a derivative of 2'-Deoxyguanosine which is a nucleoside analog. Synonyms: 2'-Deoxy-guanosine 5'-(Tetrahydrogen triphosphate)? 3'-(Dihydrogen phosphate) Triethylamine Salt. Molecular formula: C10H17N5O16P4 xC6H15N. Mole weight: 587.16.
2'-Deoxyguanosine 3'-O-L-valinyl ester
2'-Deoxyguanosine 3'-O-L-valinyl ester, a biomedical marvel, presents itself as a formidable ally against viral infections and various cancer forms. This extraordinary compound serves as the backbone for nucleic acid synthesis and integrates seamlessly into DNA during replication. Offering its antiviral potency, it combats the likes of herpes simplex virus and human immunodeficiency virus (HIV).
2'-Deoxyguanosine-5'-carboxylic acid
2'-Deoxyguanosine-5'-carboxylic acid, an indispensable compound in the biomedical sector, exhibits profound significance in the realm of DNA synthesis and repair. Its pivotal role renders it a commendable instrument in unraveling the intricacies of DNA damage and repair mechanisms. Furthermore, this compound contributes to the advancement of therapeutic medications, specifically targeting afflictions like cancer and viral infections. The multifaceted nature of its applications bestows upon it an irreplaceable value, enhancing the landscape of biomedical research. Synonyms: 1-(2-amino-1,?6-dihydro-6-oxo-9H-purin-9-yl)?-1,?2-dideoxy-b-D-erythro-pentofuranuronic acid; (2S,3S,5R)-5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-carboxylic acid. CAS No. 82534-56-3. Molecular formula: C10H11N5O5. Mole weight: 281.23.
2'-Deoxyguanosine-5'-diphosphate
2'-Deoxyguanosine-5'-diphosphate is a fundamental biomedical entity enabling DNA research and development, exercising a pivotal function in the intricate process of DNA replication and repair. Synonyms: dGDP; Deoxyguanosine 5'-diphosphate; deoxyguanosine diphosphate; 2'-deoxyguanosine 5'-(trihydrogen diphosphate); 2'-Deoxy-GDP; Guanosine, 2'-deoxy-, 5'-(trihydrogen pyrophosphate); Guanosine, 2'-deoxy-, 5'-pyrophosphate. Grades: ≥98% by HPLC. CAS No. 3493-9-2. Molecular formula: C10H15N5O10P2. Mole weight: 427.20.
2'-Deoxyguanosine-5'-O-(1-Boranotriphosphate)
2'-Deoxyguanosine-5'-O-(1-Boranotriphosphate), a noteworthy chemical entity in the biomedical domain, poses pivotal significance in the research fraternity. This substrate is ubiquitously employed to study the kinases, which includes DNA polymerases. The intricate correlation of 2'-Deoxyguanosine-5'-O-(1-Boranotriphosphate) and cognitive disorders like cancer, Alzheimer's, and Parkinson's unveils the potential of this substrate to identify biomarkers and potential targets for therapeutic interventions. Synonyms: 1-Borano-dGTP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H18N5O12P3B. Mole weight: 504.00.