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5-epi Emtricitabine Carboxylic Acid
5-epi Emtricitabine Carboxylic Acid is an impurity of 5-epi Emtricitabine; an epimer of Emtricitabine which is a nucleoside reverse transcriptase inhibitor approved for treatment of HIV-1. Emtricitabine also has antagonistic activity against the hepatitis B virus. Synonyms: (2R,5R)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid. Molecular formula: C8H8FN2O4S. Mole weight: 261.23.
5-Ethyl-2'-deoxyuridine-d5
Isotope labelled 5-Ethyl-2'-deoxyuridine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil, a potent antineoplastic agent in clinical use. Synonyms: 2'-Deoxy-5-ethyluridine-d5; 5-Ethyl-1-(2'-deoxy-β-D-ribofuranosyl)uracil-d5; 5-Ethyl-2'-deoxyuridine-d5; 5-Ethyldeoxyuridine-d5; Aedurid-d5; EDU-d5; EUDR-d5; Edoxudine-d5; Epoxudine-d5; ORF 15817-d5; RWJ 15817-d5; β-5-Ethyl-2'-deoxyuridine-d5; β-5-Ethyldeoxyuridine-d5. Molecular formula: C11H11D5N2O5. Mole weight: 261.29.
5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine is a remarkable antiviral compound, used in research of herpes simplex virus (HSV) infections. By functioning as a nucleoside analog and effectively hampering viral DNA enhancement, it efficaciously obstructs viral replication. The distinctive structure of this compound renders it exceptionally promising for extensive biomedical exploration and drug development directed towards HSV-associated afflictions. Synonyms: Uridine, 2'-deoxy-5-ethyl-, 3',5'-bis(p-chlorobenzoate). Grades: 98%. CAS No. 25137-84-2. Molecular formula: C25H22Cl2N2O7. Mole weight: 533.36.
5'-Ethynyl-2'-deoxycytidine
5'-Ethynyl-2'-deoxycytidine (EdC) is a nucleoside analog that inhibits replication of the herpes simplex virus-1 (HSV-1) KOS strain (ID50 = 0.2 μg/mL). It also reduces virus-induced cytopathogenicity of HSV-1, HSV-2, and vaccinia virus strains in PRK cells (MICs = 0.2-0.4, 1-2, and 5 μg/ml, respectively). Synonyms: EdC; 2'-deoxy-5-Ethynylcytidine; 5-Ethynyl-2-deoxycytidine. Grades: ≥98%. CAS No. 69075-47-4. Molecular formula: C11H13N3O4. Mole weight: 251.2.
5-Ethynylcytidine
5-Ethynylcytidine is an eminent biomedical compound, employed as a nucleoside analog. It vigorously impedes viral replication and ushers in the righteous realm of apoptosis within malignant cells. Indeed, its profound efficacy can be attributed to its tenacious interference with nucleic acid research and development and relentless disruption of protein functionality. Synonyms: 5-ethynyl-cytidine. Grades: ≥ 97% (HPLC). CAS No. 65223-78-1. Molecular formula: C11H13N3O5. Mole weight: 267.24.
5-Ethynylpyrimidine
5-Ethynylpyrimidine, an indispensable compound within the biomedical sector, assumes a pivotal function in the synthesis of pharmaceuticals and innovative drug candidates targeting a myriad of diseases. Its exceptional attributes facilitate profound investigations crucial for advancing therapeutic interventions across diverse medical domains including cancer, viral infections, and neurological disorders. Synonyms: Pyrimidine, 5-ethynyl-(9CI). Grades: 95%. CAS No. 153286-94-3. Molecular formula: C6H4N2. Mole weight: 104.11.
5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-5'-O-acetyl-b-L-ribofuranosyl)-uracil is a highly efficacious synthetic nucleoside analog utilized in the research of human immunodeficiency virus (HIV) infection. Its mechanism of action involves robust inhibition of HIV reverse transcriptase, impeding viral replication and significantly ameliorating viral burden. Synonyms: 5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-5'-O-acetyl-β-L-ribofuranosyl)-uracil; [(2R,5S)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methyl acetate. CAS No. 1421336-32-4. Molecular formula: C11H11FN2O5. Mole weight: 270.22.
5-Fluoro-1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-b-L-arabinofuranosyl)-uracil is also known as F-deoxy-F-BzAraU, utilized in the research of specific DNA viruses including herpes simplex and varicella-zoster. Through hinderance of viral DNA replication, it effectively curbs the dissemination and development of viral infections. Synonyms: 1-(3,5-Di-O-benzoyl-2-deoxy-2-fluoro-beta-L-arabinofuranosyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione; 2,4(1H,3H)-Pyrimidinedione, 1-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-L-arabinofuranosyl)-5-fluoro-. CAS No. 178687-87-1. Molecular formula: C23H18F2N2O7. Mole weight: 472.40.
5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil is a robust compound, used in research of diverse viral infections, breast, lung and gastrointestinal tumors. Embodying exceptional inhibitory activity, this compound serves as an invaluable asset for the research and development of both antiviral and antitumor. Synonyms: 5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-β-L-lyxofuranosyl)-uracil. Grades: ≥95%. Molecular formula: C28H24F2N2O5. Mole weight: 506.51.
5-Fluoro-1-(b-L-ribofuranosyl)-uracil
5-Fluoro-1-(b-L-ribofuranosyl)-uracil is a powerful antineoplastic compound, exhibiting immense potential in research of diverse malignancies. Renowned for its impact on inhibiting DNA enhancement and impeding cell proliferation, this remarkable compound emerges as an invaluable asset in the research and development of oncology. Synonyms: 1-beta-L-Ribofuranosyl-5-fluorouracil; L-5-Fluorouridine; 1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-fluoro-pyrimidine-2,4-dione; 5-Fluoro-1-(β-L-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione; L-β-Ribofuranosyl-5'-fluorouracil. Grades: 95%. CAS No. 77210-26-5. Molecular formula: C9H11FN2O6. Mole weight: 262.19.
5-Fluoro-2'-deoxyuridine 5'-Monophosphate Ammonium Salt (up to 20% 3'-monophosphate)
5-Fluoro-2'-deoxyuridine 5'-Monophosphate is used in the preparation of diaminomitosene nucleotide derivatives with anti-neoplastic activity. Synonyms: 2'-Deoxy-5-fluoro-5'-uridylic Acid Ammonium Salt. Grades: 90%. Molecular formula: C9H12FN2O8P xNH3. Mole weight: 326.17.
5-Fluoro-3-pyridylboronic acid
5-Fluoro-3-pyridylboronic acid is used as a pharmaceutical intermediate. Synonyms: ACMC-209qir; Boric acid fluoride-3-5; SCHEMBL27969; 3-fluoro-5-pyridineboronic acid; (5-fluoranylpyridin-3-yl)boronic acid; AKOS005258007; ZINC169743450; AB31983; 5-Fluoropyridine-3-boronic acid. Grades: > 98 % (HPLC). CAS No. 872041-86-6. Molecular formula: C5H5BFNO2. Mole weight: 140.91.
5-Fluoro-4'-C-methylcytidine
5-Fluoro-4'-C-methylcytidine, an exceptional antiviral compound, exhibits remarkable potential in biomedical applications for targeting diverse viral infections. Its unparalleled efficacy extends to RNA viruses, such as hepatitis C virus (HCV) and the notorious SARS-CoV-2. This nucleotide analog disrupts viral RNA synthesis, effectively impeding viral replication. Captivating studies have unveiled its promising role as a therapeutic agent for combating viral diseases, thereby instigating renewed interest in intensified research and development of cutting-edge antiviral treatments. Proceeding into the realm of this scientific wonder, we embark upon a profound exploration. Synonyms: Cytidine, 5-fluoro-4'-C-methyl-; 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-5-methyloxolan-2-yl]-5-fluoropyrimidin-2-one; 4-Amino-1-[5-deoxy-4-(hydroxymethyl)-α-L-lyxofuranosyl]-5-fluoro-2(1H)-pyrimidinone. Grades: ≥95%. CAS No. 791585-24-5. Molecular formula: C10H14FN3O5. Mole weight: 275.23.
5-Fluoro-4'-C-methyluridine
5-Fluoro-4'-C-methyluridine is a pivotal chemical compound widely employed in the biomedical sector, showcasing remarkable antiviral attributes. It is tailored for research of viral infections. Synonyms: Uridine, 5-fluoro-4'-C-methyl-; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-5-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione; 1-[5-Deoxy-4-(hydroxymethyl)-α-L-lyxofuranosyl]-5-fluoro-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 660845-69-2. Molecular formula: C10H13FN2O6. Mole weight: 276.22.
5'-Fluoro-5'-deoxy-adenosine
5'-Fluoro-5'-deoxy-adenosine is an impressive antiviral compound, exhibiting inhibitory efficacy in studying an array of viral afflictions including influenza, herpes and HIV. This compound, revered for its impeccable inhibitory capabilities restraining viral replication while thwarting viral dissemination, emerges as an auspicious contender for the development of avant-garde antiviral researchs. Synonyms: 5'-FDA; 5'-fluoro-5'-deoxyadenosine; 5'-deoxy-5'-fluoroadenosine. CAS No. 731-98-6. Molecular formula: C10H12FN5O3. Mole weight: 269.23.
5-Fluoro ent-Lamivudine Acid D-Menthol Ester
5-Fluoro ent-Lamivudine Acid D-Menthol Ester is an intermediate in the synthesis of Emtricitabine, which is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Synonyms: (2S,5R)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid (1S,2R,5S)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester; (1S,2R,5S)-2-Isopropyl-5-methylcyclohexyl (2S,5R)-5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylate; 1,3-Oxathiolane-2-carboxylic acid, 5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-, (1S,2R,5S)-5-methyl-2-(1-methylethyl)cyclohexyl ester, (2S,5R)-. Grades: 98%. CAS No. 764659-79-2. Molecular formula: C18H26FN3O4S. Mole weight: 399.48.
5-Fluoropyrimidin-2-One beta-Ribofuranoside
5-Fluoropyrimidin-2-One beta-Ribofuranoside is an antiviral compound with applications in the research of diverse ailments, encompassing specific cancers and viral afflictions. By impeding crucial DNA research and development and replication processes, this pharmaceutical compound thwarts cancer cell propagation and viral replication. Synonyms: 1beta-D-Ribofuranosyl-5-fluoropyrimidin-2(1H)-one; 5-fluorozebularine; 5-F-Zebularine; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidin-2-one; 5-Fluoro-zebularine; 5-Fpor; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidin-2(1H)-one; 5-Fluoropyrimidin-2-one riboside; 5-Fluoropyrimidin-2-one ribonucleoside; 5-fluoropyrimidin-2-one-ribonucleoside; NSC 318509; 2(1H)-Pyrimidinone, 5-fluoro-1-beta-D-ribofuranosyl-. CAS No. 64967-16-4. Molecular formula: C9H11FN2O5. Mole weight: 246.19.
Protected 5-Fluorouracil N-β-D-Glucuronide, a derivative of 5-Fluorouracil. 5-Fluorouracil N-β-D-Glucuronide unlike its O-glucuronide analog does not possess significant antitumor activity. Synonyms: 1-Deoxy-1-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-β-D-glucopyranuronic Acid Methyl Ester, 2,3,4-Triacetate. CAS No. 77476-81-4. Molecular formula: C17H19FN2O11. Mole weight: 446.34.
5-Fluorouridine-13C,15N2
5-Fluorouridine-13C,15N2 is a compound useful in organic synthesis. Synonyms: 5-FU-3C, 15N2. Grades: 98%; 98.8% atom 13C,15N. Molecular formula: C8[13C]H11F[15N]2O6. Mole weight: 265.17.
5-Fluorouridine 5'-Diphosphate Galactose
5-Fluorouridine 5'-Diphosphate Galactose is a crucial molecule in biomedicine used for treating certain diseases. It plays a vital role as a competitive inhibitor of UDP-galactose 4-epimerase, which is involved in the synthesis of glycoproteins and glycolipids. This product finds applications in the development of targeted therapies for cancer, as it acts by inhibiting the galactosylation process essential for tumor growth and metastasis. Synonyms: Fudp-5. CAS No. 92748-40-8. Molecular formula: C15H23FN2O17P2. Mole weight: 584.29.
5-Fluorouridine-5'-diphosphate sodium salt
5-Fluorouridine-5'-diphosphate sodium salt, a pivotal biomedicine entity, demonstrates profound significance in diverse ailments, particularly cancer. Operating as an efficient anticancer intervention, this sodium salt derivative effectively impedes the expansion and reproduction of malignant cells. Its mechanism involves interrupting DNA synthesis, thereby facilitating the control over specific cancer variants. Molecular formula: C9H14FN2O12P2. Mole weight: 422.15.
5-Fluorouridine-5'-monophosphate sodium salt
5-fluorouridine 5'-monophosphate is a pyrimidine ribonucleoside 5'-monophosphate having 5-fluorouracil as the pyrimidine component. It has a role as a drug metabolite. It is a pyrimidine ribonucleoside 5'-monophosphate and an organofluorine compound. It derives from a uridine 5'-monophosphate. Synonyms: 5F-UMP. Molecular formula: C9H12FN2O9P. Mole weight: 342.17 (free acid).
5-Fluorouridine-5'-O-b-D-galactopyranoside
5-Fluorouridine-5'-O-b-D-galactopyranoside is also known as FUG, meticulously employed for the efficacious research of an array of intricate and multifaceted cancers. It magnanimously arrests the pernicious proliferation and dissemination of malignant cell. Synonyms: Gal-FUrd; 5-Fluoro-D-uridine-5'-O-b-D-galactopyranoside; 5'-O-beta-D-Galactosyl-5-fluorouridine; 5'-O-Galactosyl-5-fluorouridine; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxolan-2-yl]-5-fluoropyrimidine-2,4-dione. Grades: 95%. CAS No. 149965-92-4. Molecular formula: C15H21FN2O11. Mole weight: 424.33.
5-Fluorouridine-5'-triphosphate triethylammonium salt
5-Fluorouridine-5'-triphosphate triethylammonium salt, an indispensable compound within the field of biomedicine, serves as a pivotal reagent. Its essence lies in its ability to serve as a substrate for RNA synthesis, permitting the infusion of the vital anticancer agent, 5-fluorouracil, into RNA molecules. Synonyms: Uridine 5'-(tetrahydrogen triphosphate),5-fluoro-,compd with N,N-diethylethanamine(1:3)(9CI). Grades: 95%. Molecular formula: C33H74N6O15P3F. Mole weight: 906.89.
5-Fluorouridine-diphosphate disodium salt
5-Fluorouridine-diphosphate disodium salt, a potent biochemical, holds great promise in treating cancer. Its dual mechanism of RNA synthesis inhibition and nucleotide metabolism inhibition leads to its effectiveness in minimizing tumor growth. Remarkably, it has been proven to specifically target breast, colon, and pancreatic cancers. Clinical insights indicate that it is applied in combination chemotherapy to achieve maximum efficacy. Synonyms: 5-Fluorouridine 5'-(Trihydrogen Diphosphate) disodium salt; 5-Fluoro-Udp disodium salt. Grades: ≥97% by HPLC. Molecular formula: C9H11FN2Na2O12P2. Mole weight: 466.11.
5-Formyl-2'-deoxycytidine-5'-Triphosphate
5-Formyl-2'-deoxycytidine-5'-Triphosphate (5F-dCTP) is a paramount ingredient as a modified nucleotide employed for investigations pertaining to the intricate domain of epigenetics and DNA modification, specifically in the comprehensive scrutiny of DNA methylation and gene expression. Synonyms: 5-Formyl-dCTP; 5-fdCTP; 5-CHO-dCTP; 5-Fo-dCTP; 2'-Deoxy-5-Formylcytidine 5'-(Tetrahydrogen Triphosphate); 5-formyl-deoxycytidine triphosphate. Grades: ≥90% by AX-HPLC. Molecular formula: C10H16N3O14P3. Mole weight: 495.10.
5-Formyl-2'-deoxyuridine-5'-Triphosphate
5-Formyl-2'-deoxyuridine-5'-Triphosphate - an essential synthetic nucleotide that's proven incredibly effective in biomedical research. Most notably, its use in conjunction with DNA polymerases has provided invaluable insight into the mechanisms behind mutations and their correction. But that's not all - this revolutionary molecule has even been shown to increase the sensitivity of cancer cells to chemotherapy drugs. Researchers worldwide trust 5-Formyl-2'-deoxyuridine-5'-Triphosphate to deliver consistent and reliable results whilst paving the way for new discoveries. Synonyms: 5-Formyl-dUTP; 5-CHO-dUTP; 5-Fo-dUTP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H15N2O15P3. Mole weight: 496.10.
5-formyl-2'-O-methylcytidine
5-formyl-2'-O-methylcytidine is an intriguing and intricate biochemical, having promising anti-cancer attributes. Synonyms: Cytidine, 5-formyl-2'-O-methyl-; 4-Amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde. Grades: ≥95%. CAS No. 176858-79-0. Molecular formula: C11H15N3O6. Mole weight: 285.26.
5-Formyl-?2'-?O-?methyluridine
5-Formyl-2'-O-methyluridine is an intriguing compound boasting remarkable potential in combatting the propagation of specific viral ailments. Its aptitude to encumber the RNA enhancement process of RNA viruses. Synonyms: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2,4-dioxopyrimidine-5-carbaldehyde. CAS No. 220090-12-0. Molecular formula: C11H14N2O7. Mole weight: 286.24.
5-Formyl-CTP
5-Formyl-CTP is a paramount compound, holding great significance for elucidating RNA metabolism and signaling pathways. Functioning as a modified nucleotide, it actively participates in RNA formation as a substrate during transcription. By facilitating the exploration of RNA processing, modifications and diverse cellular processes such as gene expression and regulation, this compound serves as a powerful tool for comprehensive studies. Synonyms: 5-Formylcytidine-5'-Triphosphate; 5-fCTP; 5-FoCTP. Grades: ≥95% by AX-HPLC. Molecular formula: C10H16N3O15P3. Mole weight: 511.17.
5-Formyl dC III CE Phosphoramidite
5-Formyl dC III CE Phosphoramidite is a paramount compound, unveiling its indispensable role within DNA sequencing and research and development. This prodigious recompound is an epitome of efficacy, facilitating the introduction of 5-formyl deoxycytidine (dC) modifications into the intricate tapestry of DNA strands. Synonyms: 5'-O-(dimethoxytrityl)-N4-(4-methoxybenzoyl)-5-(1,3-dioxan-2-yl)-2'-deoxycytidine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Aminolink phosphoramidite. Molecular formula: C51H60N5O11P. Mole weight: 950.02.
5-Formylindole-CE Phosphoramidite
5-Formylindole-CE Phosphoramidite, a critical reagent utilized to create modified nucleotides integrating into synthetic DNA/RNA molecules, is a significant contributor to the development of specific and effective drugs employed for the remediation of viral and bacterial infections, genetic disorders, cancer, and other fatal diseases. Synonyms: 5'-Dimethoxytrityl-2'-deoxy-3-formylindole-ribofuranosyl, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C44H50N3O7P. Mole weight: 763.86.
5-Formyl-UTP
5-Formyl-UTP is an indispensable constituent predominantly applied in investigations pertaining to RNA modifications and transcriptional regulation. This invaluable compound contributes to the research of diverse medical conditions, including cancer. By acting as a substrate for RNA labeling and detection, it expedites the exploration of these ailments. Furthermore, its integration into RNA sequences facilitates an enhanced comprehension of RNA metabolism and intricate cellular mechanisms. Synonyms: 5-Formyluridine-5'-Triphosphate; 5-fUTP; 5-FoUTP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H15N2O16P3. Mole weight: 512.15.
5-(Furan-2-yl)-2'-deoxyuridine
5-(Furan-2-yl)-2'-deoxyuridine, a groundbreaking antiviral compound widely employed in the field of biomedicine, holds remarkable potential for combatting pernicious herpes viruses. Through its remarkable capacity to impede viral DNA synthesis, it effectively stifles the replication of the herpes simplex virus (HSV), consequently furnishing a promising therapeutic avenue for HSV infections. Grades: ≥ 97%. CAS No. 92233-50-6. Molecular formula: C13H14N2O6. Mole weight: 294.26.
5'-(Furan-2-yl)-2'-O-methyluridine
5'-(Furan-2-yl)-2'-O-methyluridine, an extraordinary biomedicine compound, exhibits remarkable efficacy in combating a wide range of viral infections, such as hepatitis C and influenza. By impeding RNA synthesis, this nucleoside analog effectively obstructs viral replication, thereby curbing their proliferation. Distinguished by its distinctive structure, it precisely targets viral polymerases, presenting a highly promising and pioneering approach to antiviral therapy. Synonyms: 5-(Furan-2-yl)-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5-Furan-2-yl-2'-O-Methyl uridine. Grades: ≥95%. CAS No. 2095417-32-4. Molecular formula: C14H16N2O7. Mole weight: 324.29.
5'-(Furan-2-yl)-5'-O-DMT-2'-O-methylcytidine
5'-(Furan-2-yl)-5'-O-DMT-2'-O-methylcytidine is a remarkable biomedical compound, operating as an unrivaled antiviral warrior. This astounding compound zealously stifles viral replication, catapulting it to the forefront of viral ailment research. By engaging in a precisely orchestrated dance with intricate RNA viruses, it emerges as an illustrious contender for the annihilation of these infectious assailants. Synonyms: 5-Furan-2-yl-2'-O-methyl-5'-O-DMTr-cytidine; 5-Furan-2-yl-2'-O-methyl-5'-O-(4,4'-dimethoxytrityl)cytidine. Grades: ≥95%. CAS No. 2095417-02-8. Molecular formula: C35H35N3O8. Mole weight: 625.67.
5-(Furan-2-yl)-dC CEP
5-(Furan-2-yl)-dC CEP, a fundamental compound extensively utilized in the biomedical field, holds immense significance for the synthesis of altered nucleosides. Its indispensable role lies in the progression of pharmaceutical agents aimed at combatting an array of ailments including malignant neoplasms, viral afflictions, and hereditary disorders. CAS No. 1119734-65-4. Molecular formula: C50H54N5O9P. Mole weight: 899.97.
5'-GalNAc C3 Phosphoramidite
5'-GalNAc C3 Phosphoramidite is a building block for oligonucleotide synthesis containing GalNAc (N-acetylgalactosamine) modification. In biomedicine, it is used for the targeted delivery of nucleic acid therapeutics to treat various diseases, including cancer, viral infections, and genetic disorders. The GalNAc modification enhances cellular uptake and facilitates delivery to specific tissues and organs, improving therapeutic efficacy. Synonyms: (4- (Trimethoxytrityloxymethyl) -1- (6- (4- (3, 4, 6-O-triacetyl-2-acetylamino-2-deoxy-β -D-galactopyranosyl) butanamido) hexanoyl) piperidin-4-yl) methyl-O-[ (2-cyanoethyl) - (N, N-diisopropyl) ] phosphoramidite. Molecular formula: C62H88N5O17P. Mole weight: 1206.38.
5'-Hexachloro-Fluorescein CE Phosphoramidite(6-HEX)
5'-Hexachloro-Fluorescein CE Phosphoramidite (6-HEX), a cutting-edge phosphoramidite fluorescent dye reagent, expertly designed for both the labeling and detection of DNA and RNA sequences. With its superior sensitivity, this reagent is ideal for use in a variety of experiments, including gel electrophoresis, high-throughput sequencing, and hybridization. This innovative technology not only boasts impressive capabilities for real-time PCR, but is also an essential tool for gene expression analysis. Experience the unparalleled precision of 6-HEX, and revolutionize your research today. Grades: >95% by HPLC. Molecular formula: C46H52CI6N3O10P. Mole weight: 1050.62.
5'-Hexynyl CE Phosphoramidite
5'-Hexynyl CE Phosphoramidite, an essential reagent in biomedical research for oligonucleotide synthesis, offers versatility in sequencing modification through its alkyne functionality, enabling conjugation with diverse biomolecules. The reagent presents vast potential in critical fields such as gene therapy, drug discovery, and disease diagnosis and management. Its unique characteristics position it as a promising asset in achieving complex nucleotide sequencing, furthering our understanding of genetic health and disease. Molecular formula: C15H27N2O2P. Mole weight: 298.37.
5-hme-CTP
5-hme-CTP, a nucleotide analog, has been found to selectively activate purinergic P2Y1 receptors, thereby enhancing biomedical research efforts aimed at uncovering cellular signaling pathways relevant to diverse biological phenomena such as platelet activation. Given its multifaceted role, it comes as no surprise that beyond being a great tool for scientific inquiry, 5-hme-CTP holds great potential for therapeutic interventions in diseases associated with compromised cellular function, such as stroke, multiple sclerosis, and Alzheimer's disease. Synonyms: 5-Hydroxymethylcytidine-5'-Triphosphate; 5-hm-CTP; 5-HmCTP; 5-Hydroxymethyl-CTP; 5-(Hydroxymethyl)cytidine 5'-triphosphoric acid. Grades: ≥90% by AX-HPLC. Molecular formula: C10H18N3O15P3. Mole weight: 513.18.
5'-Hydrazino-5'-deoxyguanosine
5'-Hydrazino-5'-deoxyguanosine is a valuable biomolecule acting as a key reagent in DNA and RNA research for specialized investigations. It has shown significant potential in the research and development of anti-viral and anti-cancer therapies. Synonyms: 5'-deoxy-2',3'-O-methylethylidene-5'-methylaminoadenosine; 5'-deoxy-5'-methylamino-2',3'-isopropylideneadenosine; 5'-methylamino-O2',O3'-isopropylidene-5'-deoxy-adenosine. CAS No. 1189743-60-9. Molecular formula: C10H15N7O4. Mole weight: 297.27.
5-Hydroxy-CTP
5-Hydroxy-CTP is a metabolite assuming a pivotal function in the intricate process of nucleic acid and RNA research, seamlessly acting as a precursor to the revered CTP. Its versatility extends further, encompassing intricate investigations pertinent to pharmaceutical discovery as well as the efficacious intervention against a spectrum of ailments, notably viral infections and enigmatic neurological disorders. Synonyms: 5-Hydroxycytidine-5'-Triphosphate; 5hoCTP; 5-OH-CTP. Grades: ≥95% by AX-HPLC. Molecular formula: C9H16N3O15P3. Mole weight: 499.1.
5-Hydroxycytidine
5-Hydroxycytidine is a nucleoside derivative primarily used in compound for studying the role of modified nucleosides in cancer therapy and antiviral drug development. With its potential antitumor and antiviral activities, 5-Hydroxycytidine serves as an important tool in the exploration of drug targets and research strategies for various types of cancers and viral infections. Synonyms: 4-Imino-1-pentofuranosyl-1,4-dihydropyrimidine-2,5-diol; 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxypyrimidin-2-one. CAS No. 39638-73-8. Molecular formula: C9H13N3O6. Mole weight: 259.22.
5-(Hydroxymethyl)-2',3'-O-(1-methylethylidene)cytidine is used in the synthesis of tRNA's anticodon stem and loop domain containing the 5-formylcytidine modification. Also, it is an intermediate used in 5-Formylcytidine synthesis, which is a modified nucleoside found at the first position of the anticodon of bovine mitochondrial tRNAMet. Synonyms: Furo[3,4-d]-1,3-dioxole Cytidine Deriv. CAS No. 72472-12-9. Molecular formula: C13H19N3O6. Mole weight: 313.31.
5-Hydroxymethyl-2'C-methyluridine
5-Hydroxymethyl-2'C-methyluridine is a paramount compound employed in the biomedical domain, exhibiting exceptional potential in research of a myriad of ailments, including cancer and viral infections. Unveiling its distinctive configuration and properties, this compound assumes a momentous function in the realm of pharmaceutical development and exploration.
5-Hydroxymethyl-2'-deoxyuridine-5'-Triphosphate
5-Hydroxymethyl-2'-deoxyuridine-5'-Triphosphate is a pivotal compound, holding paramount significance in DNA labeling and sequencing endeavors. Functioning as a modified nucleotide triphosphate, it exhibits competencies in assimilating within DNA during the process of polymerization, thereby facilitating the identification of DNA alterations. This invaluable compound assumes a critical role in the comprehensive exploration of epigenetic modifications and the consequential impact of oxidative stress on DNA replication and repair pathways. Synonyms: 5-hmdUTP; 5-Hydroxymethyl-dUTP; Hydroxymethyldeoxyuridine triphosphate. Grades: ≥90% by AX-HPLC. CAS No. 14167-70-5. Molecular formula: C10H17N2O15P3. Mole weight: 498.10.
5-Hydroxymethyl-2'-O-(2-methoxyethyl)uridine
5-Hydroxymethyl-2'-O-(2-methoxyethyl)uridine is an acclaimed compound, quashing viral replication and precipitously diminishing the burden of viral entities. Synonyms: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 2095417-51-7. Molecular formula: C13H20N2O8. Mole weight: 332.31.
5-Hydroxymethyl-dC
It is a modified pyrimidine that is capable of producing interstrand cross-links in duplex DNA. It can be analyzed to quantify DNA hydroxymethylation levels in biological samples. Synonyms: 5-Hydroxymethyl-2'-deoxycytidine; hm-Dcmp; 2'-deoxy-5-(hydroxymethyl)cytidine; 5-(Hydroxymethyl)deoxycytidine; 4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 7226-77-9. Molecular formula: C10H15N3O5. Mole weight: 257.24.
5-Hydroxymethyl-dC II-CE Phosphoramidite
5-Hydroxymethyl-dC II-CE Phosphoramidite, a frequently employed reagent in genomic research, is indispensable for synthesizing modified oligonucleotides. Its site-specific labeling aptitude benefits the subsequent detection and analysis of DNA and RNA strands. Besides, the application of 5-Hydroxymethyl-dC II-CE Phosphoramidite in anti-cancer and anti-HIV therapies development also renders it an integral tool in the medical field. Synonyms: 5'-Dimethoxytrityl-5-hydroxymethyl-N,O-carbamoyl-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N,5-(Carbonyloxymethylene)-3'-O-[diisopropylamino(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine. CAS No. 1257247-42-9. Molecular formula: C41H48N5O9P. Mole weight: 785.82.
5-Hydroxymethyldeoxycytidylic acid
5-Hydroxymethyldeoxycytidylic acid, an indispensable component in the realm of biomedicine, stands as a compound of paramount importance. Renowned for its potential therapeutic value, this nucleoside analog assumes a pivotal role in combatting DNA-related ailments, encompassing malignant neoplasms and pervasive viral afflictions. Researchers earnestly employ this organic entity to unravel the intricate intricacies of DNA structure-function associations and genetic manipulation techniques. Synonyms: 5-Hydroxymethyldeoxycytidylic acid; 5-Hmdcyt; 5-Hydroxymethyldeoxycytidylate; 2'-deoxy-5-(hydroxymethyl)cytidine 5'-(dihydrogen phosphate). Grades: 95%. CAS No. 13009-95-5. Molecular formula: C10H16N3O8P. Mole weight: 337.22.
5-Hydroxymethyl uridine
5-Hydroxymethyl uridine is an esteemed compound, having applications in research of varied neurological ailments encompassing Alzheimer's disease and Parkinson's disease. Synonyms: 5-Hydroxymethyluridine; 5-(hydroxymethyl)uridine; Uridine, 5-(hydroxymethyl)-; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 30414-00-7. Molecular formula: C10H14N2O7. Mole weight: 274.23.
5-I-dC-CE Phosphoramidite
5-I-dC-CE Phosphoramidite, an essential reagent in the synthesis of modified oligonucleotides, serves as a precursor for 5-iodo-2'-deoxycytidine-containing oligos, exhibiting impressive therapeutic efficacy against viral infections and cancer. Its incorporation into oligonucleotides results in improved stability and enzyme recognition, priming itself as a potent candidate for targeted molecular therapeutics. Synonyms: 5'-Dimethoxytrityl-N-benzoyl-5-iodo-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 178925-44-5. Molecular formula: C46H51IN5O8P. Mole weight: 959.83.
5'-Iodo-2',3'-dideoxyuridine
5'-Iodo-2',3'-dideoxyuridine, known for its potent antiviral properties, is a remarkable therapeutic agent utilized in combating herpes simplex virus (HSV) infections. Through its ability to selectively impede viral DNA synthesis, it effectively hampers the replication of HSV, consequently providing relief from symptoms and shortening the duration of outbreaks. Molecular formula: C9H11N2O4I. Mole weight: 338.10.
5-Iodo-2'-C-methylcytidine
5-Iodo-2'-C-methylcytidine, an indispensable compound within biomedicine, encompasses formidable antiviral and antineoplastic attributes. Renowned for its unique nucleoside analogue nature, this compound finds extensive employment in pharmaceutical advancements targeting RNA viruses such as coronaviruses, flaviviruses, and retroviruses. Its unparalleled configuration and intricately orchestrated mechanism of action render it a propitious contender in the battle against diverse viral infections and specific malignancies. Synonyms: 5-Iodo-2'-C-methyl-1-β-D-ribofuranosylcytosine; 5-Iodo-2'-C-methyl Cytidine; 5-Iodo-2'-β-C-methyl cytidine; 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-5-iodopyrimidin-2-one. Grades: ≥95%. CAS No. 2072145-60-7. Molecular formula: C10H14IN3O5. Mole weight: 383.14.
5-Iodocytidine
5-Iodocytidine is an intermediate for research in the field of nucleic acids and nucleic acid-protein interactions. Synonyms: 1-β-D-Ribofuranosyl-5-iodocytosine; 5-Iodo-cytidine; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one. Grades: ≥ 95 %. CAS No. 1147-23-5. Molecular formula: C9H12IN3O5. Mole weight: 369.11.
5-Iodocytidine 5'-triphosphate sodium salt
5-Iodocytidine 5'-triphosphate sodium salt is a highly significant recompound in the field of compound, exhibiting profound importance in diverse areas including DNA sequencing, mutagenesis studies, nucleic acid development, RNA labeling research, gene expression analysis and viral diagnostics. Synonyms: Sodium ((2R,3S,4R,5R)-5-(4-amino-5-iodo-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate; 59259-76-6. CAS No. 59259-76-6. Molecular formula: C9H15IN3O14P3. Mole weight: 609.05.
5-Iodo-dCTP
5-Iodo-dCTP is a crucial tool in biomedicine used for various applications. It serves as a labeled nucleotide analog and finds extensive use in DNA sequencing and labeling techniques. This product enables precise detection and identification of specific DNA sequences, aiding in genetic research, disease diagnostics, and drug development. It is commonly employed in studies related to cancer mutations and genetic disorders. Synonyms: 5I-dCTP; 5-Iodo-2'-deoxycytidine-5'-Triphosphate. Grades: ≥90% by AX-HPLC. CAS No. 31747-59-8. Molecular formula: C9H15N3O13P3I (free acid). Mole weight: 593.05 (free acid).
5-Iodo-dUMP
5-Iodo-dUMP is a critical compound extensively utilized in the biomedical field with pivotal function in obstructing DNA enhancement. It can impede the proliferation of malignant cells and thwarting the metastatic cascade. Synonyms: (5I-dUMP); 5-Iodo-2'-deoxyuridine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1763-02-6. Molecular formula: C9H12N2O8PI (free acid). Mole weight: 434.08 (free acid).
5-Iodo-N4-DMF-2'-deoxycytidine
5-Iodo-N4-DMF-2'-deoxycytidine is a highly potent and efficacious antiviral compound, finding application in the therapeutic research of diverse viral affections, notably those stemming from DNA viruses. Its exceptional effectiveness becomes evident in research of infections caused by herpes simplex virus (HSV) and cytomegalovirus (CMV). Leveraging its distinctive molecular composition, this compound exerts its therapeutic action as a nucleoside analog, inducing disruption of viral replication mechanisms and consequentially impeding the development of viral pathologies. Synonyms: N4-DMF-5-I-dC; Cytidine, 2'-deoxy-N-[(dimethylamino)methylene]-5-iodo-; N-(Dimethylaminomethylene)-5-iodo-2'-deoxycytidine. Grades: ≥97% by HPLC. CAS No. 717876-93-2. Molecular formula: C12H17IN4O4. Mole weight: 408.20.
5-Iodouridine
It is a Rho-GTPase cell protein inhibitor. Synonyms: NSC 523375; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione; 2,4-Dihydroxy-5-iodo-1-β-D-ribofuranosylpyrimidine; 5-Iodo-1-(β-D-ribofuranosyl)uracil. Grades: ≥95%. CAS No. 1024-99-3. Molecular formula: C9H11IN2O6. Mole weight: 370.10.
5-(isopentenylaminomethyl)-2'-O-methyluridine
5-(Isopentenylaminomethyl)-2'-O-methyluridine, an essential nucleoside analog, holds a pivotal position in RNA modification research for its impact on RNA function and structure. Besides, it excites the scientific community with its reported antiviral efficacy against HIV. Researchers can leverage this potent tool in Unlocking the secrets of RNA modification and curbing viral infections. Synonyms: Uridine, 2'-O-methyl-5-[[(3-methyl-2-butenyl)amino]methyl]-. CAS No. 872710-80-0. Molecular formula: C16H25N3O6. Mole weight: 355.39.
5-(isopentenylaminomethyl)-2-thiouridine
5-(Isopentenylaminomethyl)-2-thiouridine, a modified nucleoside utilized in RNA research within the biomedical sector, has exhibited a notable influence over translation regulation. Its promising implications in both cancer and viral infections have experts exploring its therapeutic potential towards numerous maladies. Alongside its role in RNA research, 5-(Isopentenylaminomethyl)-2-thiouridine possesses the power to revolutionize the treatment methods of various diseases. Synonyms: Uridine, 5-[[(3-methyl-2-butenyl)amino]methyl]-2-thio-. CAS No. 872710-78-6. Molecular formula: C15H23N3O5S. Mole weight: 357.43.
5'-Maleimide-Modifier Phosphoramidite
5'-Maleimide-Modifier Phosphoramidite is a phosphoramidite reagent used for chemical modification of single-stranded DNA or RNA oligonucleotides. This product facilitates the site-specific attachment of a maleimide-activated molecule to the 5'-end of the oligonucleotide, allowing for a wide range of applications in biomedicine, such as targeted drug delivery and detection of specific biomolecules for disease diagnosis and therapy. Synonyms: 2-(1,7-Dimethyl-3,5-dioxo-10-oxa-4-azatricyclo[5.2.1.02,6]dec-8-en-4-yl)-ethyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C21H32N3O5P. Mole weight: 437.47.
5-Me-dC Brancher Phosphoramidite
5-Me-dC Brancher Phosphoramidite, an indispensable instrument for biopharmaceutical R&D, is widely utilized in the production of customized oligonucleotides to study cancer, viral infections, and novel therapeutic strategies. Its superior synthesis efficiency and high-quality performance have made it a top choice among scientists in the field. Synonyms: 5'-Dimethoxytrityl-N4-(O-levulinyl-6-oxyhexyl)-5-Methyl-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C51H68N5O10P. Mole weight: 942.10.
5-Methoxy-2-thiouridine
5-Methoxy-2-thiouridine, an extraordinary biomedical substance, manifests remarkable therapeutic efficacy across a myriad of afflictions. Its profound antioxidative attributes not only combat oxidative stress but also unveil groundbreaking prospects in combating neoplasms such as leukemia and pancreatic cancer. Synonyms: 5-Methoxy-1-beta-D-ribofuranosyl-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one. Grades: ≥95%. CAS No. 30771-43-8. Molecular formula: C10H14N2O6S. Mole weight: 290.29.
5-Methoxy-4-thiouridine
5-Methoxy-4-thiouridine, a revolutionary biomedical marvel, is an exquisite solution meticulously formulated for combating an array of treacherous viral afflictions. Harnessing its extraordinary antiviral potential, this unparalleled creation wages a relentless war against notorious RNA viruses such as HIV-1 and hepatitis C virus, engendering their impotence and annihilation. With its awe-inspiring ability to stymie viral replication and impede viral protein synthesis, it shines as the epitome of viral deterrence. Synonyms: 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxy-4-thioxo-3,4-dihydropyrimidin-2(1H)-one; 5-methoxy-4-thio-uridine; 5-Methoxy-1-(β-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone. Grades: ≥95%. CAS No. 37805-89-3. Molecular formula: C10H14N2O6S. Mole weight: 290.29.
5-Methoxy-4'-thiouridine
5-Methoxy-4'-thiouridine, a modified nucleoside that has been widely investigated for its viable therapeutic applications in tackling viral infections and cancer, has shown great promise in blocking viral replication and instigating apoptosis in malignant cells. This anti-tumor activity might stem from the influential impact it has on RNA transcription and translation by interfering in DNA synthesis. Grades: ≥95%. Molecular formula: C10H14N2O6S. Mole weight: 290.29.
5-Methoxycarbonylmethyl-2'-O-methyluridine
5-Methoxycarbonylmethyl-2'-O-methyluridine, an indispensable biomedical compound, is extensively employed in the realm of research and development for antiviral drugs. This multifaceted compound assumes a paramount role in tackling diverse viral infections, meticulously targeting distinctive RNA viruses. Its eminent significance stems from its peculiar chemical structure which confers it with the potential to exhibit vigorous antiviral activity, hindering viral replication. Synonyms: 5-(Methoxycarbonyl)methyl-2'-O-Methyl uridine; (2-OMe-MCM5U); 2'-O-Methyluridine 5-acetic acid methyl ester; 1,2,3,4-Tetrahydro-1-(2-O-methyl-beta-D-ribofuranosyl)-2,4-dioxo-5-pyrimidineacetic acid methyl ester; 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-1-(2-O-methyl-b-D-ribofuranosyl)-2,4-dioxo-, methyl ester; Methyl 2-(1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetate. Grades: ≥95%. CAS No. 60197-31-1. Molecular formula: C13H18N2O8. Mole weight: 330.29.
5-methoxycarbonylmethyl-2-thiouridine
5-(Methoxycarbonylmethyl)-2-thiouridine can be used as analyte in biological study for attomole quantification and global profile of RNA modifications in study of epitranscriptome of human neural stem cells. It can also be used to biological computational studies to provide insights into effects of modified ribonucleotides and Mg2+ on structures and stabilities of tRNAs. A trace nucleoside, isolated from yeast transfer RNA. A nucleoside in the anticodon at the wobble position of some Saccharomyces cerevisiae bacteria. Synonyms: 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-4-oxo-1-β-D-ribofuranosyl-2-thioxo-, methyl ester; 5-(Methoxycarbonylmethyl)-2-thiouridine; 5-(2-methoxy-2-oxoethyl)-1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 5-(2-methoxy-2-oxoethyl)2-thiouridine. Grades: ≥95%. CAS No. 20299-15-4. Molecular formula: C7H8N2O3S. Mole weight: 332.33.