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5'-O-Tosylguanosine
As an intermediate in the synthesis of Adenosine 5'-Triphosphate Disodium Salt, 5'-O-Tosylguanosine is a multifunctional nucleoside triphosphate used in cells as a coenzyme of intracellular energy transfer. Synonyms: Guanosine 5'-(4-Methylbenzenesulfonate); NSC 62628. CAS No. 39947-33-6. Molecular formula: C17H19N5O7S. Mole weight: 437.43.
5-O-Trityl-2,3'-anhydrothymidine
5-O-Trityl-2,3'-anhydrothymidine is a vital compound in the biomedical industry. It is commonly used in the synthesis of novel antiviral drugs for the treatment of various viral diseases. This product exhibits potent antiviral activity, making it an essential tool in drug development research targeting viral infections. Its reliable quality ensures accurate and reproducible results in multiple applications within the biomedical field. Synonyms: (2R,3R,5R)-8-Methyl-3-((trityloxy)methyl)-2,3-dihydro-2,5-methanopyrimido[2,1-b][1,5,3]dioxazepin-9(5H)-one; 2,3'-Anhydro-1-(2-deoxy-5-O-trityl-beta-D-threo-pentofuranosyl)thymine; 5-O-Triphenylmethyl-2-deoxy-2,3-didehyrothymidine. Grades: ≥95%. CAS No. 25442-42-6. Molecular formula: C29H26N2O4. Mole weight: 466.53.
5'-O-trityl-2'-deoxyinosine
5'-O-trityl-2'-deoxyinosine, a nucleoside analog of immense therapeutic potential, has displayed tremendous promise in the treatment of a variety of cancers and viral infections. Its efficacy in cancer treatment stems from its inherent ability to disrupt DNA replication and transcription, while its antiviral activity is primarily attributed to its potent inhibition of viral reverse transcriptase - an enzyme that is quintessential for the replication of the HIV virus. Synonyms: 5'-Trt-2'-dI; 5''-O-trityl-2''-deoxyinosine; Trt-dI; 5'-O-Trt-dI; Inosine, 2'-deoxy-5'-O-(triphenylmethyl)-; 2'-Deoxy-5'-O-tritylinosine. Grades: ≥98% by HPLC. CAS No. 911430-74-5. Molecular formula: C29H26N4O4. Mole weight: 494.54.
5-O-Trityl-3'-deoxy-3'-fluorothymidine
An intermediate in the synthesis of thymidine monophosphate analogues. Uses: An intermediate in the preparation of thymidine monophosphate analogues. Synonyms: 3'-Deoxy-3'-fluoro-5'-O-(triphenylmethyl)thymidine. Grades: 95%. CAS No. 135197-63-6. Molecular formula: C29H27FN2O4. Mole weight: 486.53.
5'-O-Tritylinosine
KIN59 is a purine riboside derivative that suppresses thymidine phosphorylase (TPase). TPase is an enzyme catalyzing the reversible phosphorolysis of pyrimidine deoxynucleosides to 2-deoxy-d-ribose-1-phosphate and their respective pyrimidine bases. KIN59 noncompetitively inhibits TPase-induced angiogenesis in the chorioallantoic membrane assay. Synonyms: 5'-Trt-rI; (2R,3R,4S,5R)-9-(3,4-Dihydroxy-5-trityloxymethyl-tetrahydrofuran-2-yl)-1,9-dihydropurin-6-one; KIN-59; Inosine, 5'-O-(triphenylmethyl)-; 5'-O-(triphenylmethyl)-inosine. Grades: ≥98% by HPLC. CAS No. 4152-77-6. Molecular formula: C29H26N4O5. Mole weight: 510.55.
5'-O-Tritylthymidine
5'-O-Tritylthymidine (CAS# 7791-71-1) is a useful research chemical compound. Synonyms: 5'-O-Trityl-thymidine. Grades: ≥ 95 % (HPLC). CAS No. 7791-71-1. Molecular formula: C29H28N2O5. Mole weight: 484.54.
5'-Oxo-2'-deoxy-8,5'-cycloadenosine
5'-Oxo-2'-deoxy-8,5'-cycloadenosine is a potential therapeutic compound used in the biomedical industry. It exhibits promising anti-viral and immunomodulatory activities, making it an ideal candidate for treating viral infections and autoimmune diseases. Grades: ≥ 97%. CAS No. 869355-08-8. Molecular formula: C10H9N5O3. Mole weight: 247.21.
5-Phenylcytidine
5-Phenylcytidine, an indispensable pharmaceutical compound extensively employed in the realm of biomedical research, showcases its exceptional efficacy in modulating a plethora of disorders, encompassing malignancies, viral pathologies, and neurological afflictions. Remarkably, owing to its distinctive chemical configuration, this compound unveils an auspicious potential as an anti-neoplastic, antiviral, and neuroprotective agent, thereby serving as a profound instrument in forging pioneering curative strategies and unraveling intricate mechanisms underlying diseases. Synonyms: 4-Amino-1-(β-D-furanosyl)-5-phenyl-2(1H)-pyrimidinone; 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-phenylpyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 83866-19-7. Molecular formula: C15H17N3O5. Mole weight: 319.31.
5'-Phosphoryl-(3'-amino-3'-deoxyguanylyl)-(3'-5')-3'-amino-3'-deoxycytidine is a highly significant compound extensively employed in the biomedical sector, holding immense therapeutic potential for research of viral infections. Moreover, this remarkable compound exhibits auspicious outcomes in impeding the proliferation of neoplastic cells. Synonyms: [(2R,3S,4R,5R)-4-Amino-2-[[(2R,3S,4R,5R)-4-amino-5-(4-amino-2-oxo-pyri midin-1-yl)-3-phosphonooxy-oxolan-2-yl]methoxymethyl]-5-(2-amino-6-oxo-3H-purin-9-yl)oxolan-3-yl]oxyphosphonic acid; 5'-Guanylic acid,3'-amino-3'-deoxycytidylyl-(5'-3')-3'-amino-3'-deoxy; Padgdc. CAS No. 109679-54-1. Molecular formula: C19H28N10O13P2. Mole weight: 666.43.
5-Propargyloxy-dU CEP
5-Propargyloxy-dU CEP is a vital compound in biomedicine, commonly used to develop nucleotide analogues for antiviral or anticancer drugs. With its unique properties, it facilitates the synthesis of modified DNA molecules that specifically target and inhibit viral replication or cancer cell growth. CAS No. 1311144-61-2. Molecular formula: C42H49N4O9P. Mole weight: 784.83.
5-Propynyl-2'-deoxycytidine-5'-Triphosphate
5-Propynyl-2'-deoxycytidine-5'-Triphosphate is a vital tool in compound used for various applications. It functions as a chain terminator during DNA research and development, specifically targeting cancer cells. This compound is commonly used in the development of anticancer drugs and research focused on understanding and studying hematological malignancies. Synonyms: 5-Propynyl-dCTP; 5-(1-Propynyl)-2'-deoxycytidine 5'-triphosphoric acid. Grades: ≥90% by AX-HPLC. Molecular formula: C12H18N3O13P3. Mole weight: 505.20.
5-Propynyl-2'-deoxyuridine-5'-Triphosphate
5-Propynyl-2'-deoxyuridine-5'-Triphosphate - a powerful and versatile nucleoside analogue that integrates into DNA during replication, impeding viral DNA polymerase and bringing about chain termination. Its broad-spectrum antiviral qualities have made it a primary focus for treating viral infections, including herpes simplex and varicella zoster viruses. Synonyms: 5-Propynyl-dUTP; alpha-Ethylidynethymidine 5'-triphosphoric acid. Grades: ≥90% by AX-HPLC. Molecular formula: C12H17N2O14P3. Mole weight: 506.10.
5'-Pyrene Cap Phosphoramidite
5'-Pyrene Cap Phosphoramidite is a molecule used in the field of biomedicine as a reagent during oligonucleotide synthesis. It is commonly used to introduce fluorescence properties into nucleic acid molecules for use in various diagnostic techniques and imaging studies. Additionally, this product may be used to develop new drugs for the treatment of cancer, viral diseases, and other genetic-based conditions. Synonyms: (N-(1-pyrenylmethyl)-pyrrolidin-3-oxy)-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite. Molecular formula: C30H36N3O2P. Mole weight: 501.60.
5'-QD-1 CE Phosphoramidite
5'-QD-1 CE Phosphoramidite, a vital pharmaceutical product in biomedicine and molecular biology research, is an exceptional building block that guarantees high-purity oligonucleotide synthesis, enriched with fluorescent labelling capabilities for the thorough detection of genetic diseases and mutations. With its extraordinary stability, this remarkable tool fuses chemical innovation and cutting-edge science - a force to be reckoned with in modern gene therapy. Grades: >95% by HPLC. Molecular formula: C34H45N8O5P. Mole weight: 676.75.
5'-QD-2 CE Phosphoramidite
5-QD-2 CE Phosphoramidite, a crucial biomedicine product of the nucleotide-based therapeutic field, stands as an unparalleled aid in the modification of oligonucleotides, especially antisense oligonucleotides and siRNAs. With its enhanced stability and efficacy, the biomedical industry holds it in high esteem, treating it as an essential ingredient for targeted disease treatment research. Grades: >95% by HPLC. Molecular formula: C33H43N8O6P. Mole weight: 678.73.
5'-(R)-C-Methyl-2-thiouridine
5'-(R)-C-Methyl-2-thiouridine, a nucleoside derivative widely explored within the biomedical domain, emerges as an intriguing candidate endowed with antiviral prowess. Elucidating its intricate mechanisms of action renders this compound an invaluable asset in the realm of pioneering antiviral therapeutics. Synonyms: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-((R)-1-hydroxyethyl)tetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one. Molecular formula: C10H14N2O5S. Mole weight: 274.29.
5'(R)-C-Methyl-5-fluorouridine
5'(R)-C-Methyl-5-fluorouridine is an impactful antiviral nucleoside analog extensively utilized within the biomedical realm, showcasing remarkable selectivity in its cytotoxicity towards specific cancer cells. Its pivotal role lies in research of diverse viral infections, exemplified by its utilization in hepatitis C. This remarkable compound impeccably assumes the capacity of a nucleoside reverse transcriptase inhibitor, effectively hindering viral replication and, thereby, facilitating the mitigating of viral ailments. Synonyms: 5'-C-Methyl-5-fluorouridine. Grades: ≥95%. Molecular formula: C10H13FN2O6. Mole weight: 276.22.
5'(R)-C-Methyl-5-methyluridine
5'(R)-C-Methyl-5-methyluridine - an essential constituent in the biomedicine sector, precisely utilized for the advancement of antiviral medications. Demonstrating remarkable effectiveness against RNA viruses, it presents substantial value in combating viral infections. Its exceptional molecular configuration holds immense therapeutic promise, signifying a gateway for extensive examination and propitious advancements in antiviral therapeutics. Synonyms: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(1R)-1-hydroxyethyl]oxolan-2-yl]-5-methylpyrimidine-2,4-dione. Grades: ≥95%. CAS No. 129745-35-3. Molecular formula: C11H16N2O6. Mole weight: 272.25.
5'(R)-C-Methyladenosine
5'(R)-C-Methyladenosine is an extraordinary biomedical compound manifesting itself as an exquisite and highly selective viral replication suppressor. Synonyms: NSC 18193; (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-((R)-1-hydroxyethyl)tetrahydrofuran-3,4-diol; 9-(6-Deoxy-β-D-allofuranosyl)-9H-purin-6-amine; 9-(6-Deoxy-β-D-allofuranosyl)adenine. Grades: ≥95%. CAS No. 3253-81-4. Molecular formula: C11H15N5O4. Mole weight: 281.27.
5'(R)-C-Methylcytidine
5'(R)-C-Methylcytidine is a prominent pharmaceutical compound utilized in the compound sector, playing a crucial role in research of viral infections, especially those affecting the respiratory system. By effectively impeding viral replication, this compound emerges as a formidable force in diminishing the infection's intensity and duration. With its distinctive configuration and intricate mode of operation, it becomes an auspicious contender in the realm of antiviral drug development. Synonyms: 4-Amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-((R)-1-hydroxy-ethyl)-tetrahydro-furan-2-yl]-1H-pyrimidin-2-one; 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(1R)-1-hydroxyethyl]oxolan-2-yl]pyrimidin-2-one; 1-(6-deoxy-β-D-allofuranosyl)cytosine. Grades: ≥95%. CAS No. 72159-53-6. Molecular formula: C10H15N3O5. Mole weight: 257.24.
5'(R)-C-Methylguanosine
5'(R)-C-Methylguanosine, a vital research tool in the biomedical industry, is a highly intricate biomedicine product. This modified guanosine derivative holds immense significance in RNA metabolism. Its utilization primarily centers around the exploration of RNA modification's profound influence on gene expression. Moreover, this compound provides invaluable insights into the involvement of modified nucleosides in various afflictions like cancer and neurological disorders. Empowering scientific investigations, it serves as an indispensable asset for discerning the intricacies of disease pathogenesis and therapeutic interventions. Synonyms: NSC 347203; 9-(6'-Deoxy-beta-D-allofuranosyl)guanine; 2-Amino-9-(6-deoxy-β-D-allofuranosyl)-3,9-dihydro-6H-purin-6-one; 9-DAFG. Grades: ≥95%. CAS No. 85421-89-2. Molecular formula: C11H15N5O5. Mole weight: 297.27.
5'(R)-C-Methyl-N6-methyladenosine
5'(R)-C-Methyl-N6-methyladenosine is a profound biomedical compound widely employed in research investigations, serving as an exquisite analog of the indigenous RNA alteration known as N6-methyladenosine (m6A). Notably, this intriguing modification materializes as a pivotal player within epitranscriptomics. Remarkably, this chemically enhanced nucleoside pioneers the unveiling of profound insights into the intricate interplay between RNA methylation, gene expression, transcript stability is and RNA-protein interactions. Grades: ≥95%. Molecular formula: C12H17N5O4. Mole weight: 295.29.
5'(R)-C-Methyluridine
5'(R)-C-Methyluridine is an essential biomedical compound, serving as an indispensable weapon in research of viral infections and cancer. Its remarkable antiviral properties enable the effective suppression of RNA-based viruses such as hepatitis and HIV. Moreover, by actively participating in the intricate process of RNA and DNA research and development, this compound greatly aids in unraveling the complexities of genetic diseases. Synonyms: 1-(6-Deoxy-b-D-allofuranosyl)-2,4(1H,3H)pyrimidinedione; 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-((R)-1-hydroxy-ethyl)-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione; 1-(6-deoxy-β-D-allofuranosyl)uracil; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(1R)-1-hydroxyethyl]oxolan-2-yl]pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 72159-54-7. Molecular formula: C10H14N2O6. Mole weight: 258.23.
(5'S)-2'-Deoxy-8,5'-cycloadenosine
(5'S)-2'-Deoxy-8,5'-cycloadenosine is an extraordinary synthetic nucleoside, holding immense potential for biomedical applications. Its astounding antiviral capabilities against a wide array of RNA viruses, encompassing the formidable hepatitis C virus (HCV) and unruly flaviviruses. Functioning as a disruptive nucleoside analog, it effectively thwarts viral replication and impedes the viral polymerase enzyme's activity. This distinctive structure and mechanism have positioned it as a formidable contender in the realm of antiviral therapies, particularly those targeting RNA viruses. Grades: ≥ 97%. CAS No. 117182-88-4. Molecular formula: C10H11N5O3. Mole weight: 249.23.
5'-S-[3-(1,?3-Dihydro-1,?3-dioxo-2H-isoindol-2-yl)?propyl]?-2',?3'-O-(1-methylethylidene)?-5'-thio-adenosine is an intermediate in synthesizing Decarboxylated S-Adenosylmethionine Sulfate Salt, a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine. Synonyms: 2-(3-((((3aS,4S,6R,6aR)-6-(6-Amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl)thio)propyl)isoindoline-1,3-dione. CAS No. 263715-50-0. Molecular formula: C24H26N6O5S. Mole weight: 510.57.
5'-S-(3-Aminopropyl)?-5'-thio-adenosine Sulfate is an intermediate in synthesizing Decarboxylated S-Adenosylmethionine Sulfate Salt, a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine. Synonyms: (2R, 3R, 4S, 5S) -2- (6-Amino-9H-purin-9-yl) -5- ( ( (3-aminopropyl) thio) methyl) tetrahydrofuran-3, 4-diol Sulfate. CAS No. 99019-00-8. Molecular formula: C13H20N6O3S H2SO4. Mole weight: 340.41.
(5S)-5'-O-(Dimethoxytrityl)-5,6-dihydrothymidine
(5S)-5'-O-(Dimethoxytrityl)-5,6-dihydrothymidine, an essential compound utilized in the biomedical sector, holds immense significance in the development of antiviral medications. Particularly efficacious against DNA viruses, this compound's unrivaled chemical constitution and inherent characteristics render it an optimal foundational constituent for formulating remedies against diverse viral infections. Synonyms: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5,6-dihydro- (9CI); 1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-5-methyl-1,3-diazinane-2,4-dione; 5/'-O-(DIMETHOXYTRITYL)-5,6-DIHYDROTHYMIDINE; 1- ( (2R, 4S, 5R)-5- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-methyldihydropyrimidine-2, 4 (1H, 3H)-dione. Grades: ≥ 97%. CAS No. 113974-50-8. Molecular formula: C31H34N2O7. Mole weight: 546.62.
(5'S)-8,5'-Cyclodeoxyadenosine CE phosphoramidite
(5'S)-8,5'-Cyclodeoxyadenosine CE phosphoramidite is a crucial compound used in the synthesis of modified DNA strands for biomedical research. It enables the introduction of 8,5'-cyclodeoxyadenosine into nucleic acid sequences, offering opportunities for drug development and DNA-based diagnostics targeting various diseases including cancer and viral infections. Synonyms: 5'-Dimethoxytrityl-N-benzoyl-(5'S)-8,5'-cyclo-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 8,5'-Cyclo-dA CE Phosphoramidite. CAS No. 211919-91-4. Molecular formula: C47H50N7O7P. Mole weight: 855.92.
(5'S)-8,5'-Cyclodeoxyguanosine (THP) CEP
(5'S)-8,5'-Cyclodeoxyguanosine (THP) CEP, a highly sought-after compound within the biomedical industry, serves as an invaluable asset in the synthesis of therapeutic oligonucleotides. Its pivotal contribution to the realm of anti-cancer and anti-viral drug development stems from its inherent capability to seamlessly integrate modified guanosine residues into nucleic acids. Molecular formula: C28H42N7O7P. Mole weight: 619.65.
5-taurinomethyl-2-thiouridine
5-taurinomethyl-2-thiouridine - a molecularly modified nucleoside present in transfer RNA - has been lauded for its extensive usage as an auxiliary tool to bolster the effectiveness of anticancer drugs. Research has revealed that, drawing upon its ability to curb tumor expansion and induce apoptosis within them, 5-taurinomethyl-2-thiouridine has the potential to serve as a curative measure for cancer patients. Synonyms: Ethanesulfonic acid, 2-[[(1,2,3,4-tetrahydro-4-oxo-1-b-D-ribofuranosyl-2-thioxo-5-pyrimidinyl)methyl]amino]-. CAS No. 497258-54-5. Molecular formula: C12H19N3O8S2. Mole weight: 397.43.
5-taurinomethyluridine
5-taurinomethyluridine is a remarkable compound widely utilized in the research of neurological disorders and neurodegenerative maladies. Evidently, this exceptional compound exhibits remarkable neuroprotective attributes, coupled with its antioxidant prowess. Synonyms: Ethanesulfonic acid, 2-[[(1,2,3,4-tetrahydro-2,4-dioxo-1-b-D-ribofuranosyl-pyrimidinyl)methyl]amino]-. CAS No. 497258-53-4. Molecular formula: C12H19N3O9S. Mole weight: 381.36.
5'-tert-Butyldimethylsilyloxy-2'-deoxyguanosine
5'-tert-Butyldimethylsilyloxy-2'-deoxyguanosine, a modified guanosine, is a pivotal compound in biomedical research, facilitating DNA synthesis. It provides an ideal substrate for DNA polymerases while also being a key ingredient in nucleic acids chemistry, useful in exploring the relationship between DNA damage and cancer. Additionally, its application as a tool to focus on the structure-function links of DNA-repair enzymes has been extensive, unveiling novel research opportunities. Synonyms: 5'-O-TBDMS-2'-deoxyguanosine; 2-Amino-9-((2R,4S,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 5'-O-TBDMS-dG; 2'-Deoxy-5'-O-[dimethyl(2-methyl-2-propanyl)silyl]guanosine. Grades: ≥97% by HPLC. CAS No. 51549-33-8. Molecular formula: C16H27N5O4Si. Mole weight: 381.51.
5'-tert-butyldimethylsilyloxy-N4-acetyl-5-iodo-cytidine, a pharmaceutical intermediate renowned for its antiviral properties, is widely employed in the production of antiviral drugs. Its efficacy has been empirically proven against herpes simplex virus, cytomegalovirus, and varicella-zoster virus. Additionally, this product serves as a potent weapon in the biomedical industry's battle against numerous other viral infections that threaten public health. Synonyms: 5'-O-TBDMS-N4-acetyl-5-iodo-cytidine. Grades: ≥97% by HPLC. Molecular formula: C17H28IN3O6Si. Mole weight: 525.42.
5'-Tetrachloro-Fluorescein CE Phosphoramidite(6-TET)
5'-Tetrachloro-Fluorescein CE Phosphoramidite (6-TET) is an exceptional nucleoside derivatizing reagent. Significantly, its high sensitivity and specificity are beneficial for the fluorescence-based detection methods when examining single nucleotide polymorphisms, gene expression, or DNA sequencing. Moreover, novel investigations show that it could be imperative when studying mitochondrial DNA damages commonly implicated in both cancer and neurological disorders. Synonyms: 6-[(4,7,2',7'-Tetrachloro-3',6'-dipivaloylfluoresceinyl)-carboxamido]-hexyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: >97% by HPLC. Molecular formula: C46H54CI4N3O10P. Mole weight: 981.73.
5-TFA-aha-2'-Deoxycytidine
5-TFA-aha-2'-Deoxycytidine, a synthetic nucleoside analog with potential therapeutic properties against multiple cancer types including breast, lung, and pancreatic cancer, works by incorporating into the DNA strands of cancer cells resulting in the inhibition of cellular replication and ultimately, cell death. Its effective application in combatting cancer renders it an intriguing area of study towards developing novel cancer treatments. Synonyms: TFA-aha-dC; 5-TFA-aha-dC. Grades: ≥98% by HPLC. Molecular formula: C20H28F3N5O6. Mole weight: 491.46.
5-TFA-ap-2',3'-Dideoxycytidine
5-TFA-ap-2',3'-Dideoxycytidine, a nucleoside analogue implemented as an antiviral agent to counteract human immunodeficiency virus (HIV) infections, functions by obstructing the reverse transcriptase enzyme crucial for viral replication. Its utilization as a potent antiviral compound has been studied extensively due to its promising therapeutic capabilities in restraining the detrimental spread of HIV. Synonyms: 5-[(Trifluoracetyl)amino]propynyl-ddC; 5-TFA-ap-ddC; 2',3'-Dideoxy-5-[3-[(trifluoroacetyl)amino]-1-propynyl]-cytidine; Cytidine, 2',3'-dideoxy-5-[3-[(trifluoroacetyl)amino]-1-propynyl]-; 5-(3-Trifluoroacetamido-1-propynyl)-2',3'-dideoxycytidine; N-(3-{4-Amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-2-oxo-1,2-dihydro-5-pyrimidinyl}-2-propyn-1-yl)-2,2,2-trifluoroacetamide. Grades: ≥97% by HPLC. CAS No. 114748-58-2. Molecular formula: C14H15F3N4O4. Mole weight: 360.29.
5-TFA-ap-2',3'-Dideoxyuridine
5-TFA-ap-2',3'-Dideoxyuridine is an exceptionally potent antiviral compound extensively used in the research of viral infections, especially the ones attributed to DNA viruses. Its outstanding efficacy lies in its ability to thwart viral DNA enhancement, thereby effectively curbing viral replication and averting the pernicious expansion of the viral affliction. Synonyms: 5-[(Trifluoracetyl)amino]propynyl-ddU; 5-(3-trifluoroacetamido-1-propynyl)-2',3'-dideoxyuridine; 2',3'-Dideoxy-5-[3-(trifluoroacetylamino)-1-propynyl]uridine; Uridine, 2',3'-dideoxy-5-[3-[(trifluoroacetyl)amino]-1-propynyl]-; 5-TFA-AP-DDU; 2,2,2-Trifluoro-N-(3-{1-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl}-2-propyn-1-yl)acetamide. Grades: ≥97% by HPLC. CAS No. 114748-60-6. Molecular formula: C14H14F3N3O5. Mole weight: 361.27.
5'-Thiol-Modifier C6
5'-Thiol-Modifier C6, a biomedical agent, serves as a transformative tool for DNA sequence modification, gear towards tailor-made treatment of neoplastic disorders, viral contagions, as well as genetic anomalies. By minimizing harm to healthy cells while directing medicines to diseased cells, its role in therapeutic regimes for cancer, viral infections, and genetics is eminent and valuable. Synonyms: S-Trityl-6-mercaptohexyl-1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N,N-Diisopropylamide phosphorous acid (2-cyanoethyl)[6-(tritylthio)hexyl] ester. CAS No. 116919-17-6. Molecular formula: C34H45N2O2PS. Mole weight: 576.78.
5'-TMPS
5'-TMPS is a potent, competitive inhibitor that regulates enzymes. It can interact with thymidine-5'-monophosphate. Synonyms: Thymidine- 5'- O- monophosphorothioate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 15548-51-3. Molecular formula: C10H15N2O7PS (free acid). Mole weight: 338.3 (free acid).
5'-Tosyl-2'-deoxy Guanosine
In the synthesis of α,β-methylene-2'-deoxynucleoside 5'-triphosphates, novel 2'-deoxycyclonucleosides are used as noncleavable substrates for DNA polymerases. Uses: A novel 2'-deoxycyclonucleosides. Synonyms: 5'-(4-Methylbenzenesulfonate) 2'-Deoxyguanosine. Grades: 95%. CAS No. 109954-64-5. Molecular formula: C17H19N5O6S. Mole weight: 421.43.
A derivative of 5'-Tosyl-2'-deoxy Cytidine, which is a nucleoside used to synthesize vitamin B12 coenzyme analogs containing 2'-deoxynucleoside. Synonyms: 5'-(4-Methylbenzenesulfonate)-3'-tert-butyldimethylsilyl-2'-deoxycytidine. Molecular formula: C22H33N3O6SiS. Mole weight: 495.66.
As a derivative of 5'-Tosyl-2'-deoxy Cytidine, 5'-Tosyl-2'-deoxy-3'-tert-butyldimethylsilyl-N-[(dimethylamino)methylene]-Cytidine is a nucleoside used to synthesize vitamin B12 coenzyme analogs containing 2'-deoxynucleoside. Synonyms: 5'-(4-Methylbenzenesulfonate)-3'-tert-butyldimethylsilyl-N-[(dimethylamino)methylene]-2'-deoxycytidine. Molecular formula: C25H38N4O6SiS. Mole weight: 550.74.
5'-Tosyl Adenosine
5'-Tosyl Adenosine (CAS# 5135-30-8) is a compound useful in organic synthesis. Synonyms: Adenosine 5'-(4-Methylbenzenesulfonate); 5'-O-Toluenesulfonyladenosine; 5'-Tosyladenosine. Grades: 95 %. CAS No. 5135-30-8. Molecular formula: C17H19N5O6S. Mole weight: 421.43.
5-(Trifluoromethyl)cytidine
5-(Trifluoromethyl)cytidine, a remarkable antiviral compound, demonstrates exceptional potency in research of RNA virus-induced infections. This compound can be used in flaviviruses and picornaviruses, including notorious hepatitis C and poliovirus. Its mechanism of action involves the inhibition of viral replication and cellular protein research and development. Synonyms: 5-trifluoromethylcytidine; 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-(trifluoromethyl)pyrimidin-2-one. Grades: ≥95%. CAS No. 76514-02-8. Molecular formula: C10H12F3N3O5. Mole weight: 311.21.
5'-Trimethoxystilbene Cap Phosphoramidite
5'-Trimethoxystilbene Cap Phosphoramidite is an indispensable biomedical wonder unfurling boundless possibilities in the realm of oligonucleotide research and development, amplifying the horizons of drug development. This ingenious compound bestows researchers with an unparalleled capacity to fabricate customized nucleic acids. Synonyms: (3,4,5-trimethoxystilbene-4'-yl)-(3-carboxamidopropyl)-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite. Molecular formula: C30H42N3O6P. Mole weight: 571.65.
5'-Trt-N2-ibu-rG
5'-Trt-N2-ibu-rG, a nucleoside analog, exhibits strong potential as an effective anticancer agent, as it has been demonstrated to impede the growth and spread of certain cancer cell types, including leukemia and breast cancer. The mechanism behind its tumor suppression lies in its specific targeting of the RNA polymerase II enzyme, a key factor in the transcription of cancer-promoting genes, thus providing a promising avenue for chemotherapy. Synonyms: 5'-O-Trt-N2-ibu-rG. Grades: ≥98% by HPLC. Molecular formula: C33H32N5O6. Mole weight: 595.65.
5'-UMPS
5'-UMPS is a potent, competitive inhibitor that regulates enzymes. It can interact with uridine-5'-monophosphate. Synonyms: Uridine- 5'- O- monophosphorothioate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 15548-52-4. Molecular formula: C9H13N2O8PS (free acid). Mole weight: 340.3 (free acid).
5'-Uridylic acid disodium salt xhydrate
5'-Uridylic acid disodium salt xhydrate is a key component for RNA synthesis, while also serving as a top-rated dietary supplement that effectively boosts immune function and reduces inflammation. As if its unrivaled use wasn't enough, it has additionally exhibited remarkable therapeutic potential in treating Hepatitis and liver diseases, making it a must-have in any scientific lab or healthcare setting. Synonyms: Uridine 5'-monophosphate disodium salt hydrate. CAS No. 681435-27-8. Molecular formula: C9H13N2Na2O10P. Mole weight: 386.16.
5-Vinylcytidine
5-Vinylcytidine, an analog of nucleoside with promising prospects in combating specific malignancies like acute myeloid leukemia (AML) and solid tumors, presents an appealing avenue for investigation. Additionally, this compound serves as a viable substrate in synthesizing nucleoside-derived therapeutics tailored for cancer cell suppression. Comprehensive insight into its chemical attributes and prospective utilities can be obtained through perusal of diverse biomedical online platforms. Grades: ≥95%. CAS No. 1846584-62-0. Molecular formula: C11H15N3O5. Mole weight: 269.25.
5'-Xanthylic Acid Triethylammonium Salt
5'-Xanthylic Acid Triethylammonium Salt, an invaluable biomedical element renowned for its intrinsic therapeutic potential, is a meticulously formulated remedy, designed with utmost precision to combat an array of afflictions. Its distinctive attribute as a nucleotide analog empowers it to efficaciously impede viral replication, captivatingly curbing the proliferation of meticulously targeted viruses. Synonyms: Xanthosine 5'-Monophosphate Triethylammonium Salt. Grades: 97%. Molecular formula: C22H43N6O9P. Mole weight: 566.59.
6-(1-MeBu)-ATP
6-(1-MeBu)-ATP is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach). Grades: ≥ 95% by HPLC. CAS No. 252889-13-7. Molecular formula: C15H26N5O13P3 (free acid). Mole weight: 577.3 (free acid).
6-(1-Piperizinyl)-9-(b-D-ribofuranosyl)-9H-purine
6-(1-Piperizinyl)-9-(b-D-ribofuranosyl)-9H-purine is a compound widely explored in the biomedical sector, boasting a chemical framework that amalgamates a ribofuranosyl factioning a piperizinyl component and a purine foundation. Synonyms: 6-(1-Piperizinyl)purine riboside; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-[6-(1-piperazinyl)-9H-purin-9-yl]tetrahydro-3,4-furandiol; 9H-Purine, 6-(1-piperazinyl)-9-β-D-ribofuranosyl-. Grades: ≥95%. CAS No. 121370-61-4. Molecular formula: C14H20N6O4. Mole weight: 336.35.
6,2'-Dimethyladenosine 5'-Monophosphate
6,2'-Dimethyladenosine 5'-Monophosphate was used to synthesize its ATP analog, N6,O2'-Dimethyladenosine, using phosphoenolpyruvate synthetase. Synonyms: N-Methyl-2'-O-methyl 5'-Adenylic Acid. CAS No. 60091-05-6. Molecular formula: C12H18N5O7P. Mole weight: 375.27.
6-(2H4-Furfurylamino)purine riboside
6-(2H4-Furfurylamino)purine riboside is an outstanding and discriminating antagonist, finding extensive application in the research of diverse ailments encompassing malignancy and viral infestations. It exerts its effect by precisely aiming at particular enzymatic entities, thereby inducing obstruction of anomalous cellular proliferation and impeding viral particle duplication. Synonyms: Kinetin-d4 riboside.
6-(2H4-Furfurylamino)purine riboside-5-triphosphate sodium salt
6-(2H4-Furfurylamino)purine riboside-5-triphosphate sodium salt, a fundamental compound within the biomedical sector, possesses numerous significant scientific implications. Frequently employed as a nucleotide analog for the examination of RNA or DNA metabolism, its multifaceted nature extends to pharmaceutical research, facilitating the creation and refinement of medications that combat maladies such as cancer, viral infections, and genetic disorders. Synonyms: Kinetin-d4 riboside triphosphate.
6-(2-MeBu)-ADP
6-(2-MeBu)-ADP is a precursor in the synthesis of the corresponding radio-labelled triphosphate used in the chemical genetics approach. Grades: ≥ 95% by HPLC. CAS No. 681175-77-9. Molecular formula: C15H25N5O10P2 (free acid). Mole weight: 497.3 (free acid).
6-(2-MeBu)-ATP
6-(2-MeBu)-ATP is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach). Grades: ≥ 95% by HPLC. CAS No. 252889-14-8. Molecular formula: C15H26N5O13P3 (free acid). Mole weight: 577.3 (free acid).
6-(2-Pyridylmethylthio)-9-(b-D-ribofuranosyl)purine, a significant compound in the biomedical field, is held in high regard for its prospective application in antiviral therapies. Notably, this product showcases commendable antiviral activity against a range of viral diseases, serving as an efficacious viral replication inhibitor. Synonyms: 6-(2-Pyridylmethylthio)-9-b-D-ribofuranosyl-9H-purine. Molecular formula: C16H17N5O4S. Mole weight: 375.40.
6-(2-Pyridylmethylthio)-9-β-D-ribofuranosyl-9H-purine, known as an efficacious antiviral agent, is widely employed in addressing viral infections, including hepatitis B and C. Its mechanism of action entails a targeted inhibition of viral RNA synthesis, thus impeding the replication process and averting further dissemination of the virus. Molecular formula: C16H17N5O4S. Mole weight: 375.4.
6-(3-MeBn)-ADP
6-(3-MeBn)-ADP is a precursor in the synthesis of the corresponding radio-labelled triphosphate used in the chemical genetics approach. Grades: ≥ 95% by HPLC. CAS No. 681175-78-0. Molecular formula: C18H23N5O10P2 (free acid). Mole weight: 531.4 (free acid).
6-(3-MeBn)-ATP
6-(3-MeBn)-ATP is an analogue used to specifically interact with modified receptor proteins (chemical genetics). Grades: ≥ 95% by HPLC. CAS No. 215321-95-2. Molecular formula: C18H24N5O13P3 (free acid). Mole weight: 611.3 (free acid).
6-(4-Morpholino)-9-(b-D-ribofuranosyl)-9H-purine
6-(4-Morpholino)-9-(b-D-ribofuranosyl)-9H-purine is a potent antiviral drug used in the research of certain viral infections exhibiting inhibitory activity against RNA viruses, including influenza and hepatitis C. With its unique molecular structure, this compound interferes with viral replication by targeting key enzymes involved in viral RNA enhancement. Synonyms: 6-(4-Morpholino)purine riboside; 9H-Purine, 6-(4-morpholinyl)-9-β-D-ribofuranosyl-; (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-morpholino-9H-purin-9-yl)tetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 52940-48-4. Molecular formula: C14H19N5O5. Mole weight: 337.33.
6-[(4-Nitrobenzyl)thio]-9-(b-D-ribofuranosyl)purine-5'-monophosphate disodium salt
6-[(4-Nitrobenzyl)thio]-9-(b-D-ribofuranosyl)purine-5'-monophosphate disodium salt, an exceptional pharmaceutical compound renowned for its remarkable efficacy in addressing specific malignancies and viral infections, operates via the inhibition of DNA synthesis to impede cellular proliferation. This extraordinary therapeutic agent exhibits immense potential in combating various cancers such as leukemia, lymphoma, and solid tumors. Molecular formula: C17H16N5Na2O9PS. Mole weight: 543.36.
6-[(4-Nitrobenzyl)thio]-9-β-D-ribofuranosylpurine-5'-monophosphate, Disodium Salt
Used in therapy of mouse leukemia L1210 in combinations with Nebularin and Nitrobenzylthioinosine 5'-monophosphate. Synonyms: 6-Nitrobenzylthioinosine 5'-Monophosphate Disodium Salt; 6-S-[(4-Nitrophenyl)methyl]-6-thio-5'-Inosinic Acid Disodium Salt. Grades: 98%. Molecular formula: C17H16N5Na2O9PS. Mole weight: 543.36.
6-AB-ADP
6-AB-ADP is a ligand in affinity chromatography and can be modified with fluorophores or other markers. Synonyms: N6- (4- Aminobutyl)adenosine- 5'- O- diphosphate. Grades: ≥ 95% by HPLC. CAS No. 767272-34-4. Molecular formula: C14H24N6O10P2 (free acid). Mole weight: 498.3 (free acid).
6-AE-cAMP
6-AE-cAMP is often used as a ligand for affinity chromatography of cAMP and cGMP binding proteins. Synonyms: N6- (2- Aminoethyl)adenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 66311-08-8. Molecular formula: C12H17N6O6P. Mole weight: 372.3.
6-AH-cAMP
6-AH-cAMP is a ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and other markers. Synonyms: N6- (6- Aminohexyl)adenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 66311-09-9. Molecular formula: C16H25N6O6P. Mole weight: 428.4.
6-Amino-2-(2-deoxy-β-D-ribofuranosyl)-2,5-dihydro-4H-pyrazolo-[3,4-d]-pyrimidin-4-one, a robust antiviral compound, exhibits remarkable efficacy against diverse viral infections. Its distinctive mechanism of action involves targeted suppression of viral enzymes and disruption of nucleic acid biosynthesis. Grades: ≥ 95%. CAS No. 109737-94-2. Molecular formula: C10H13N5O4. Mole weight: 267.24.
6-Amino-2,5-dihydro-2-(b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one, a nucleoside analog with remarkable potency, finds profound utility within the biomedical industry. Its proven effectiveness against viral infections, including hepatitis B and HIV, has revolutionized treatment strategies. Through the inhibition of viral replication, this compound drastically diminishes viral burden, leading to enhanced patient prognosis. Synonyms: 6-Amino-1,2-dihydro-2-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one; 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-amino-2,5-dihydro-2-β-D-ribofuranosyl-. Grades: ≥95%. CAS No. 85426-86-4. Molecular formula: C10H13N5O5. Mole weight: 283.24.
6-Amino-2-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine, a remarkable compound extensively employed in the biomedical sector, assumes profound significance. With its pivotal role in addressing a myriad of ailments and pathologies, it exhibits unparalleled effectiveness as an antiviral agent targeting viruses like hepatitis C and herpes. Synonyms: 2-Chloro-6-amino-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine. Molecular formula: C16H18ClN5O7. Mole weight: 427.8.