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| Product | Description | |
|---|---|---|
| 8-Azido-3,6-dioxaoctanoyl-AEEA | Synonyms: N3-AEEA-AEEA; 8-(8-Azido-3,6-dioxaoctanoylamido)-3,6-dioxaoctanoic acid; 2- [2- [2- [ [2- [2- (2-Azidoethoxy) ethoxy] acetyl] amino] ethoxy] ethoxy] acetic acid. Grades: 99-100% (Assay by titration). CAS No. 1254054-60-8. Molecular formula: C12H22N4O7. Mole weight: 334.30. |  |
| 8-Azidoadenosine 5'-monophosphate sodium salt | 8-Azidoadenosine 5'-monophosphate sodium salt is a biomedical compound commonly used in drug discovery and development. This product plays a vital role in studying the detailed mechanisms of various diseases, including cancer, viral infections, and neurological disorders. By acting as a precursor to adenosine triphosphate (ATP), it aids in investigating and evaluating potential therapeutic targets and drug candidates for these conditions. CAS No. 60731-47-7. Molecular formula: C10H13N8O7P. Mole weight: 388.23. | |
| 8-Azidoadenosine 5'-triphosphate tetralithium salt | 8-Azidoadenosine 5'-triphosphate tetralithium salt, a pivotal agent in the field of biomedicine, serves as an indispensable resource for the investigation of kinase activity and phosphorylation occurrences. Through its utilization as a photoaffinity probe, this compound facilitates the identification and characterization of proteins that bind to adenosine triphosphate (ATP). Its remarkably potent nature renders it a valuable asset in the realm of drug discovery and development. Grades: 85%. Molecular formula: C10H15N8O13P3. Mole weight: 548.19. | |
| 8-Azido-ATP-gamma-biotin sodium salt | 8-Azido-ATP-gamma-biotin sodium salt is a paramount recompound employed in cutting-edge biomedical investigations, exhibiting extraordinary versatility in probing protein-nucleotide interactions. Its unique azide moiety facilitates the covalent conjugation of biotin, thereby facilitating the monitoring of biotin-labeled proteins within intricate biological frameworks. Grades: 95%. Molecular formula: C25H41N12O14P3S. Mole weight: 858.65 (free acid). | |
| 8-Benzyloxy-2'-deoxyadenosine | 8-Benzyloxy-2'-deoxyadenosine, an exceptionally powerful antiviral agent, finds its application in combating formidable viral adversaries like HIV and hepatitis B. Remarkably, its inhibitory effect on viral replication and consequential hinderance of viral dissemination unveil its therapeutic prowess. This extraordinary compound, when integrated into nucleic acids, induces a perturbation in viral RNA synthesis, culminating in the abatement of viral replication. Synonyms: (2R,3S,5R)-5-(6-Amino-8-(benzyloxy)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 8-BENZYLOXY-2/'-DEOXYADENOSINE; (2R,3S,5R)-5-(6-amino-8-phenylmethoxypurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol;(2R,3S,5R)-5-[6-amino-8-(benzyloxy)-9H-purin-9-yl]-2-(hydroxymethyl)oxolan-3-ol. Grades: ≥ 97%. CAS No. 142948-07-0. Molecular formula: C17H19N5O4. Mole weight: 357.37. | |
| 8-Br-2'-O-Me-cAMP | 8-Br-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF without affecting protein kinase A. Synonyms: 8- Bromo- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 612513-13-0. Molecular formula: C11H12BrN5O6P · Na. Mole weight: 444.1. | |
| 8-Br-2'-O-Me-Guo | 8-Br-2'-O-Me-Guo is an exceptional antiviral compound massively employed within the biomedical sector, showcasing Inhibitory efficacy in the research of diverse viral maladies such as influenza and respiratory syncytial virus. Synonyms: 8- Bromo- 2'- O- methylguanosine. CAS No. 847649-49-4. Molecular formula: C11H14N6O6Br. Mole weight: 376.2. | |
| 8-Br-5'-GMP | 8-Br-5'-GMP is an analogue of 5'-GMP used as a starting structure for 8-modified 5'-GMP derivatives. Synonyms: 8- Bromoguanosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 21870-09-7. Molecular formula: C10H13BrN5O8P (free acid). Mole weight: 442.1 (free acid). | |
| 8-Br-cAMP-AM | 8-Br-cAMP-AM is a precursor of the PKA activator 8-Br-cAMP. The polar active analogue is released after metabolism of 8-Br-cAMP-AM by esterases. Synonyms: 8- Bromoadenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 97% by HPLC for mixture of isomers. CAS No. 190522-24-8. Molecular formula: C13H15BrN5O8P. Mole weight: 480.2. | |
| 8-Br-cGMP | 8-Br-cGMP is a stimulator of cGMP dependent protein kinases I α, I β & type II and cGMP-gated ion channels (cGMP agonist). Compared to cGMP, it has a superior stability. Synonyms: 8- Bromoguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 51116-01-9. Molecular formula: C10H10BrN5O7P · Na. Mole weight: 446.1. | |
| 8-Br-cGMP-AM | 8-Br-cGMP-AM is a precursor of 8-Br-cGMP, the PKG activator. The polar active analogue is released after the metabolism of 8-Br-cGMP-AM by esterases. Synonyms: 8- Bromoguanosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 97% by HPLC for mixture of isomers. CAS No. 272445-71-3. Molecular formula: C13H15BrN5O9P. Mole weight: 496.2. | |
| 8-Br-dGTP | 8-Br-dGTP is an analogue of dGTP used for receptor mapping studies and a starting structure for 8-modified dGTP derivatives. Synonyms: 8- Bromo- 2'- deoxyguanosine- 5'- O- triphosphate. Grades: ≥ 95% by HPLC. CAS No. 66891-23-4. Molecular formula: C10H15BrN5O13P3 (free acid). Mole weight: 586.1 (free acid). | |
| 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-2'-deoxyguanosine | 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-2'-deoxyguanosine is a key compound used in biomedical research for studying DNA enhancement and repair. It is primarily utilized in the development of antiviral drugs and therapies targeting viral DNA replication as well as in understanding the mechanisms underlying cell signaling pathways involved in cancer progression and autoimmune diseases. Synonyms: 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-2'-deoxy-guanosine; 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-2'-deoxyguanosine. Molecular formula: C22H40BrN5O4Si2. Mole weight: 574.66. | |
| 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-6-O-benzyl-2'-deoxyguanosine | 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-6-O-benzyl-2'-deoxyguanosine is an exceptionally influential compound integral to the research of investigating nucleosides, DNA enhancement and the development of antiviral/anticancer drugs. Synonyms: 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-6-O-benzyl-2'-deoxy-guanosine; 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-6-O-benzyl-2'-deoxyguanosine. Molecular formula: C29H46BrN5O4Si2. Mole weight: 664.78. | |
| 8-Bromo-3'-deoxy-3'-fluorotoyocamycin | 8-Bromo-3'-deoxy-3'-fluorotoyocamycin is a potent compound used in the research of various cancers and viral infections. Its mechanism of action involves inhibiting nucleic acid enhancement, leading to the suppression of tumor growth and viral replication. CAS No. 2095417-57-3. Molecular formula: C12H11BrFN5O3. Mole weight: 372.15. | |
| 8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine | 8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine, renowned for its unparalleled efficacy, stands as an indispensable entity within the illustrious biomedical realm. Revered for its unrivaled specificity, this miraculous compound has revolutionized the field by combatting DNA viruses with remarkable prowess. Its potency is particularly evident in its success against the notorious herpes simplex virus (HSV) and hepatitis B virus (HBV). Grades: ≥ 97%. CAS No. 204582-53-6. Molecular formula: C34H35BrN6O6. Mole weight: 703.59. | |
| 8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-D-ribofuranosyl]guanine | 8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-D-ribofuranosyl]guanine is an innovative compound, holding immense potential in studying a range of viral infections, with its primary focus lying on DNA viruses. Molecular formula: C22H38BrN5O5Si2. Mole weight: 588.64. | |
| 8-Bromoadenosine 3',5'-Cyclic Monophosphate Sodium Salt Monohydrate | 8-Bromoadenosine 3',5'-Cyclic Monophosphate Sodium Salt Monohydrate is a biochemical which promotes cell division. Synonyms: 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT HYDRATE; 8-BROMOADENOSINE 3',5'-CYCLIC MONOPHOSPHORIC ACID, SODIUM SALT MONOHYDRATE; 8-bromoadenosine 3',5'-cyclic monophos-phoric aci; 8-BROMOADENOSINE 3',5'-CYCLIC MONOPHOS-P HORIC ACID, NA SALT MONO. Grades: 95%. CAS No. 123334-12-3. Molecular formula: C10H10BrN5NaO6P H2O. Mole weight: 430.08. | |
| 8-Bromoadenosine 3',5'-Cyclic Monophosphothioate Sp-Isomer Sodium Salt | 8-Bromoadenosine 3',5'-Cyclic Monophosphothioate Sp-Isomer Sodium Salt is an activator of cAMP-dependent PKA. Synonyms: 1573115-90-8; Rp-8-bromo-Cyclic AMPS (sodium salt); 8-Bromoadenosine 3',5'-cyclic monophosphothiaoate, Sp-isomer sodium salt; Rp-8-bromo-Cyclic AMPS; 127634-20-2; Sp-8-bromo-Cyclic AMPS (sodium salt); sodium; (4aR,6R,7R,7aS)-6-(6-amino-8-bromopurin-9-yl)-2-oxido-2-sulfanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol; 8-Bromoadenosine3',5'-CyclicMonophosphothioateSp-IsomerSodiumSalt; 8-bromo-adenosinecyclic3',5'-[hydrogen[P(R)]-phosphorothioate],monosodiumsalt; Rp-8-bromo-Cyclic AMPS sodium salt; Rp-8-Br-cAMPS; Rp-8-bromo-cAMPS; 8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer; Sodium (4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-7-hydroxy-2-sulfanylidene-hexahydro-2|E-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate; Sodium [(2R,4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-7-hydroxy-2-oxo-hexahydro-2|E-furo[3,2-d][1,3,2]dioxaphosphinin-2-yl]sulfanide. CAS No. 1573115-90-8. Molecular formula: C10H10BrN5NaO5PS. Mole weight: 446.15. | |
| 8-Bromo-ADP | 8-Bromo-ADP is a remarkable effector on purinergic receptors, which play vital roles in numerous intricate intracellular signaling cascades. This compound offering an invaluable avenue to probe the intricate repercussions of purinergic receptor activation on diverse cellular functionalities. Synonyms: (8Br-ADP); 8-Bromo-adenosine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 23600-16-0. Molecular formula: C10H14N5O10P2Br (free acid). Mole weight: 506.10 (free acid). | |
| 8-Bromo-AMP | 8-Bromo-AMP, a pharmaceutical compound widely employed in the biomedical sector, holds significant importance in the exploration and management of diverse diseases. As a derivative of adenosine monophosphate (AMP), it possesses altered characteristics that play a pivotal role in cellular metabolism and signaling. Moreover, owing to its utilization in signal transduction pathway investigations and assessment of adenylyl cyclase activation effects, 8-Bromo-AMP showcases its versatility. Synonyms: (8Br-AMP); 8-Bromo-adenosine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 23567-96-6. Molecular formula: C10H13BrN5O7P (free acid). Mole weight: 426.12 (free acid). | |
| 8-Bromo-ATP | 8-Bromo-ATP is a potent analog of adenosine triphosphate (ATP), a crucial energy carrier in cells. Widely used in biomedicine, 8-Bromo-ATP exhibits high affinity towards purinergic receptors and is often employed to study their function and signaling pathways. Additionally, this compound serves as a substrate for various enzymatic reactions, enabling researchers to investigate ATP-dependent processes in drug discovery and disease mechanisms. Synonyms: (8Br-ATP); 8-Bromo-adenosine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 23567-97-7. Molecular formula: C10H15N5O13P3Br (free acid). Mole weight: 586.08 (free acid). | |
| 8-Bromo-dATP | 8-Bromo-dATP is a nucleoside triphosphate analog primarily used in research to investigate DNA damage and repair mechanisms. It can be incorporated into DNA during replication, leading to altered DNA structure and function. Synonyms: (8Br-dATP); 8-Bromo-2'-deoxyadenosine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 92410-99-6. Molecular formula: C10H15N5O12P3Br (free acid). Mole weight: 570.08 (free acid). | |
| 8-Bromo-GTP | 8-Bromo-GTP is a GTP analog that can inhibit GTP-hydrolase. It competitively inhibits GTPase (IC50 = 32 μM) and competes with ATP for the binding center of RNA-polymerase. Synonyms: (8Br-GTP); 8-Bromo-guanosine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 23197-98-0. Molecular formula: C10H15N5O14P3Br (free acid). Mole weight: 602.07 (free acid). | |
| 8-Bromoguanine ( 8-Br-Gua ) | 8-Bromoguanine (8-Br-Gua), a potent and versatile compound widely employed in the field of biomedicine, offers immense potential for treating a myriad of ailments, including cancer, when combined with conventional chemotherapeutic agents. Its unprecedented capability to impede the proliferation of malignant cells has been unequivocally established through comprehensive scientific inquiry, positioning it as an auspicious contender for precise and targeted therapeutic interventions. Synonyms: 2-Amino-8-bromo-6-hydroxypurine; 2-amino-8-bromo-9H-purin-6-ol; 2-amino-8-bromo-1,9-dihydropurin-6-one; 2-amino-8-bromo-3,7-dihydropurin-6-one; 2-Amino-8-bromo-1H-purin-6(7H)-one; 2-Amino-8-bromo-1,7-dihydro-6H-purin-6-one; 2-amino-8-bromopurin-6-ol; NSC 7845. Grades: ≥97% by HPLC. CAS No. 3066-84-0. Molecular formula: C5H4BrN5O. Mole weight: 230.02. | |
| 8-Bromo-N6-benzoyl-dA CEP | The 8-Bromo-N6-benzoyl-dA CEP is an indispensable chemical compound that holds immense significance within the biomedicine industry. This remarkable product serves as a linchpin in the process of developing therapeutic drugs targeted towards tackling a myriad of diseases. It exhibits unparalleled utility in the synthesis of nucleotides and nucleic acid analogs, thereby facilitating revolutionary strides in the realm of anti-cancer and anti-viral treatments. Molecular formula: C47H51BrN7O7P. Mole weight: 936.83. | |
| 8-Bromo-N9-[3',5'-O-(1,1,3,3-tetrakis(isopropyl)-1,3-disiloxanediyl)-β-D-2'-deoxyribofuranosyl]guanine | 8-Bromo-N9-[3',5'-O-(1,1,3,3-tetrakis(isopropyl)-1,3-disiloxanediyl)-β-D-2'-deoxyribofuranosyl]guanine is a highly complex compound, standing renowned due to its exceptional antiviral properties. In the pursuit of research of DNA viruses, including herpesviruses, this compound finds its purpose. Through the inhibition of viral DNA replication, it diligently curbs the propagation of viral pathogens. Synonyms: 9-[(6aR,8R,9aR)-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-amino-8-bromo-1H-purin-6-one; 2-Amino-8-bromo-9-[(6aR,8R,9aR)-2,2,4,4-tetra(propan-2-yl)tetrahydro-2H,4H,6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-3,9-dihydro-6H-purin-6-one; 8-Bromo-N9-[3',5'-O-(1,1,3,3-tetrakis(isopropyl)-1,3-disiloxanediyl)-beta-D-2'-deoxyribofuranosyl]guani; DTXSID10747232; 8-Bromo-N9-[3 inverted exclamation mark ,5 inverted exclamation mark -O-(1,1,3,3-tetrakis(isopropyl)-1,3-disiloxanediyl)-|A-D-2 inverted exclamation mark -deoxyribofuranosyl]guanine. CAS No. 769141-88-0. Molecular formula: C22H38BrN5O5Si2. Mole weight: 588.64. | |
| 8-Br-PET-cGMP | 8-Br-PET-cGMP is a stimulator of isozymes I α and I β of cGMP-dependent protein kinase, which is used as an excellent cyclic nucleotide muscle relaxants. Grades: ≥ 98% by HPLC. CAS No. 144510-04-3. Molecular formula: C18H14BrN5O7P · Na. Mole weight: 546.2. | |
| 8-BT-cAMP | 8-BT-cAMP is a selective activator of cAMP-dependent protein kinase. Compared to cAMP, it has superior stability and membrane permeability. Synonyms: 8- Benzylthioadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 50655-17-9. Molecular formula: C17H17N5O6PS · Na. Mole weight: 473.4. | |
| 8-Chloro-2'-deoxyadenosine-5'-Triphosphate | 8-Chloro-2'-deoxyadenosine-5'-Triphosphate, an altered nucleoside triphosphate used in DNA synthesis and repair research, exhibits robust inhibition of DNA polymerase and is under investigation as a cancer treatment. In sequencing technology, 8-Chloro-2'-deoxyadenosine-5'-Triphosphate serves as a valuable probe. Synonyms: 8-Chloro-dATP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H15N5O12P3Cl. Mole weight: 525.60. | |
| 8-Chloro-2'-deoxyguanosine | 8-Chloro-2'-deoxyguanosine is an extraordinary compound masterpiece, meticulously impeding the replication of the sacred DNA of tumor cells. Synonyms: 8-Chloro-2'-deoxy-D-guanosine. Grades: 98%. CAS No. 437715-62-3. Molecular formula: C10H12ClN5O4. Mole weight: 301.69. | |
| 8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate | 8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate is a key compound used in biomedical research. It acts as an adenosine receptor agonist, exhibiting therapeutic potential in the treatment of various diseases including cancer, inflammation, and neurodegenerative disorders. Its unique properties make it an essential tool for studying nucleotide signaling pathways and developing targeted therapies to combat these conditions. Molecular formula: C10H11ClN5O6P·2H2O. Mole weight: 399.69. | |
| 8-Chloroguanosine | Burstiness and perplexity encapsulate two vital aspects of effective content writing. Introducing 8-Chloroguanosine, an invaluable chemical compound extensively utilized in the biomedical sector, aimed at investigating the intricate repercussions of oxidative stress-induced DNA impairment. Its eminent significance persists in the profound comprehension of DNA repair mechanisms and replication processes, primarily applicable in pioneering disease therapies, including cancer. Synonyms: 8-Cl-Guo; 2-Amino-8-chloro-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; Guanosine, 8-chloro-; 8-Chloro-D-guanosine. Grades: ≥98% by HPLC. CAS No. 2104-68-9. Molecular formula: C10H12ClN6O6. Mole weight: 317.69. | |
| 8-Cl-5'-AMP | 8-Cl-5'-AMP is a potential metabolite of 8-chloroadenosine-3',5'-cyclic monophosphate. Synonyms: 8- Chloroadenosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 37676-40-7. Molecular formula: C10H13ClN5O7P (free acid). Mole weight: 381.7 (free acid). | |
| 8-Cl-ADP | 8-Cl-ADP is a metabolite of 8-Cl-cAMP and 8-Cl-adenosine and a precursor of 8-modified ADP derivatives. Synonyms: 8- Chloroadenosine- 5'- O- diphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 185341-69-9. Molecular formula: C10H14ClN5O10P2 (free acid). Mole weight: 461.7 (free acid). | |
| 8-Cl-X | 8-Cl-X is a potential metabolite of 8-chloro cAMP. Synonyms: 8- Chloroxanthine. Grades: ≥ 95% by HPLC. CAS No. 13548-68-0. Molecular formula: C5H3ClN4O2. Mole weight: 186.6. | |
| 8-CPT-6-Phe-cAMP | 8-CPT-6-Phe-cAMP is a selective activator of protein kinase A (cAMP agonist). It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Grades: ≥ 98% by HPLC. CAS No. 72549-36-1. Molecular formula: C22H18ClN5O6PS·Na. Mole weight: 569.9. | |
| 8-CPT-cAMP-AM | 8-CPT-cAMP-AM is a precursor of 8-CPT-cAMP, the PKA activator. 8-CPT-cAMP is released after the metabolism of 8-CPT-cAMP-AM by esterases. Synonyms: 8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 97% by HPLC for mixture of isomers. CAS No. 663941-66-0. Molecular formula: C19H19ClN5O8PS. Mole weight: 543.9. | |
| 8-[Fluo]-cAMP | 8-[Fluo]-cAMP is a fluorescent cAMP analogue (λexc494 nm, λem517 nm). Synonyms: 8- (2-[Fluoresceinyl]aminoethylthio) adenosine-3', 5'-cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 293296-57-8. Molecular formula: C33H27N7NaO11PS2. Mole weight: 815.7. | |
| 8-Hydrazinoadenosine | 8-Hydrazinoadenosine is a key compound utilized in the field of biomedicine. With its potent properties, it plays a crucial role in the development of drugs targeting various diseases. Its applications include therapies for cancer, as well as neurological and cardiovascular disorders. Synonyms: Adenosine, 8-hydrazinyl-; 8-hydrazino-adenosine; (2R,3R,4S,5R)-2-(6-amino-8-hydrazineyl-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 3868-34-6. Molecular formula: C10H15N7O4. Mole weight: 297.27. | |
| 8-Hydroxy Guanosine 5'-Triphosphate Triethylammonium Salt | 8-Hydroxy Guanosine 5'-Triphosphate is an oxidized ribonucleotide cDNA induced mutations, suggesting disturbance of genetic information during transcription and/or reverse transcription. It is a potential antiviral drug that causes mutations in genomic RNA. Synonyms: 7,8-Dihydro-8-oxoguanosine 5'-(Tetrahydrogen Triphosphate) Triethylammonium Salt; 2-Amino-9-β-D-ribofuranosylpurine-6,8(1H,9H)-dione 5'-(Tetrahydrogen Triphosphate) Triethylammonium Salt; 8-Ketoguanosine 5'-Triphosphate Bis(triethylammonium) Triethylammonium Salt; 8-OH-GTP Di-TEA Triethylammonium Salt. Grades: 95%. Molecular formula: C10H16N5O15P3 xNEt3. Mole weight: 539.18. | |
| 8-Iodo-2,3-dihydro-(1,4)dioxino(2,3-b)pyridine | 8-Iodo-2,3-dihydro-(1,4)dioxino(2,3-b)pyridine (CAS# 1228666-17-8) is a useful research chemical. Synonyms: 8-iodo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine. CAS No. 1228666-17-8. Molecular formula: C7H6INO2. Mole weight: 263.03. | |
| 8-Methoxyadenosine | 8-Methoxyadenosine is a remarkable biomedical compound with antitumor and immunosuppressive properties effectively impeding RNA enhancement and viral replication. Synonyms: Adenosine, 8-methoxy-; (2R,3R,4S,5R)-2-(6-amino-8-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 3969-27-5. Molecular formula: C11H15N5O5. Mole weight: 297.27. | |
| 8-Methylthioadenosine | 8-Methylthioadenosine, an extensively researched biochemical compound, is widely employed in biomedical studies due to its involvement in diverse physiological processes. With its potential therapeutic implications in cancer, liver diseases, and immunological disorders, this nucleoside serves as a valuable asset for exploring innovative treatment strategies within the realm of biomedicine. Synonyms: 8-Methylthio-adenosine; 8-methylsulphanyladenosine; 8-MeS-adenosine; Adenosine, 8-(methylthio)-; (2R,3R,4S,5R)-2-(6-amino-8-(methylthio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 29836-01-9. Molecular formula: C11H15N5O4S. Mole weight: 313.33. | |
| 8-Methylthioguanosine | 8-Methylthioguanosine is a synthetic nucleoside analogue impeding viral polymerases, widely applied in the research of viral maladies encompassing hepatitis C and influenza. Synonyms: 8-Methylthio-guanosine; 8-methylsulfanyl-guanosine; 8-Methylmercapto-guanosine; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-(methylthio)-1H-purin-6(9H)-one; 8-(Methylthio)guanosine. Grades: ≥95%. CAS No. 2104-66-7. Molecular formula: C11H15N5O5S. Mole weight: 329.33. | |
| 8-N3-ε-cAMP | 8-N3-ε-cAMP is a cAMP analogue used for labelling of cAMP receptors. ε-cAMP can be fluorescent through immobilization by UV light illumination, which offers a label for cAMP receptors. Synonyms: 8-Azido-1,N6-ethenoadenosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 60902-12-7. Molecular formula: C12H10N8O6P. Mole weight: 394.24. | |
| 8-NBD-cAMP | 8-NBD-cAMP is a fluorescent activator (λexc471 nm, λem536 nm) of cAMP-dependent protein kinase. 8-NBD-cAMP fluoresces strongly in hydrophobic environments. Synonyms: 8- (2-[7-Nitro-4-benzofurazanyl]aminoethylthio) adenosine-3', 5'-cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 221905-51-7. Molecular formula: C18H17N9NaO9PS. Mole weight: 589.41. | |
| 8-NBD-cGMP | 8-NBD-cGMP is a fluorescent activator of both isozymes I α and I β of cGMP-dependent protein kinase. 8-NBD-cGMP fluoresces strongly in hydrophobic environments. Synonyms: 8- (2-[7-Nitro-4-benzofurazanyl]aminoethylthio) guanosine-3', 5'-cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 115993-88-9. Molecular formula: C18H17N9NaO10PS. Mole weight: 605.41. | |
| 8-NH2-ADP | 8-NH2-ADP is an analogue of adenosine-5'-O-diphosphate used in receptor mapping studies. Synonyms: 8- Aminoadenosine- 5'- O- diphosphate. Grades: ≥ 95% by HPLC. CAS No. 65312-53-0. Molecular formula: C10H16N6O10P2 (free acid). Mole weight: 442.2 (free acid). | |
| 8-NH2-ATP | 8-NH2-ATP is an analogue of adenosine-5'-triphosphate and a metabolite of the cytotoxic nucleoside 8-aminoadenosine that can be used for receptor mapping purposes. Synonyms: 8- Aminoadenosine- 5'- O- triphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 35874-49-8. Molecular formula: C10H17N6O13P3 (free acid). Mole weight: 522.2 (free acid). | |
| 8-Nitroguanosine 2',3',5'-Triacetate | 8-Nitroguanosine derivative. Used as chemical probes in protein S-guanylation by endogenous nitrated nucleosides. Synonyms: 8-Nitroguanosine 2',3',5'-Triacetate; 1096020-95-9; [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2-amino-8-nitro-6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl acetate; (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-8-nitro-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate; J-002308; [(2R,3R,4R,5R)-3,4-bis(acetyloxy)-5-(2-amino-8-nitro-6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methyl acetate. CAS No. 1096020-95-9. Molecular formula: C16H18N6O10. Mole weight: 454.35. | |
| 8-OH-cGMP | 8-OH-cGMP is a cyclic guanosine monophosphate (cGMP) analog used in biomedical research. It acts as a second messenger in signal transduction pathways. 8-OH-cGMP is mainly utilized for studying the role of cGMP in various cellular processes, including smooth muscle relaxation, cell proliferation, and neurotransmission. It is also commonly used to investigate the pathophysiology and potential therapeutic targets in diseases related to altered cGMP signaling, such as hypertension, cardiovascular disorders, and neurodegenerative diseases. Synonyms: 8- Hydroxyguanosine- 3', 5'- cyclic monophosphate. CAS No. 21082-28-0. Molecular formula: C10H11N5O8P · Na. Mole weight: 383.2. | |
| 8-Oxo-2'-deoxyadenosine | 8-Oxo-2'-deoxyadenosine is a crucial product in the biomedical industry used for studying and treating oxidative DNA damage caused by reactive oxygen species. It is a modified form of the nucleoside adenosine and serves as a biomarker for DNA damage and oxidative stress-related diseases like cancer, neurodegenerative disorders, and cardiovascular diseases. Synonyms: 2'-Deoxy-8-oxo-adenosine;8-Oxo-dA; 6-AMINO-9-[(2R,4S,5R)-4-HYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-7H-PURIN-8-ONE; 8-Oxo-7,8-dihydro-2'-deoxyadenosine; 8-Oxo-deoxyadenosine; 8-hydroxy-2'-deoxyadenosine;6-amino-9-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-7H-purin-8-one. Grades: ≥ 95%. CAS No. 62471-63-0. Molecular formula: C10H13N5O4. Mole weight: 267.24. | |
| 8-Oxo-2'-deoxyguanosine 5'-Triphosphate Triethylamine Salt | 8-Oxo-2'-deoxyguanosine-5'-Triphosphate, considered mutagenic dNTPs, it can be incorporated into DNA by PCR using standard Taq polymerase. Synonyms: 2'-Deoxy-7,8-dihydro-8-oxo-guanosine 5'-(tetrahydrogen triphosphate) Triethylamine Salt; 8-Hydroxy-2'-deoxyguanosine 5'-triphosphate Triethylamine Salt; 8-Oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate Triethylamine Salt; 8-Oxo-dGTP Triethylamine Salt; 8-Oxo-deoxyguanosine triphosphate Triethylamine Salt. Molecular formula: C10H16N5O14P3 xC6H15N. Mole weight: 523.18. | |
| 8-Oxoadenoosine-5'-Triphosphate | 8-Oxoadenosine-5'-Triphosphate, an ATP analog crucial for cell signaling and energy transfer, is integral to studying signal transduction pathways and disease mechanisms. It also aids in the DNA sequencing and mutagenesis studies through its ability to incorporate into DNA strands. Its widespread use in research has contributed to unravelling the mysteries hidden within cancer, inflammation, and neurological disorders. Synonyms: 8-Oxo-ATP; 8-Oxo-Adenosine-5'-Triphosphate. Grades: ≥95% by AX-HPLC. CAS No. 68745-44-8. Molecular formula: C10H16N5O14P3. Mole weight: 523.10. | |
| 8-pCPT-2'-O-Me-cAMP | 8-pCPT-2'-O-Me-cAMP is a PDE-stable activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It has high lipophilicity and membrane permeability. Synonyms: 8- (4- Chlorophenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥98% by HPLC. CAS No. 634207-53-7. Molecular formula: C17H16ClN5O6PS · Na. Mole weight: 507.8. | |
| 8-pCPT-2'-O-Me-cGMP | 8-pCPT-2'-O-Me-cGMP is a PDE-stable, high lipophilic and membrane-permeant analogue. It can be used as a control since it has no activated effect on protein kinase G or Epac. Synonyms: 8- (4- Chlorophenylthio)- 2'- O- methylguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 625112-42-7. Molecular formula: C17H16ClN5O7PS · Na. Mole weight: 523.8. | |
| 8-pCPT-5'-AMP | 8-pCPT-5'-AMP is a potential metabolite of 8-pCPT-cAMP that inhibits 5'-IMP dehydrogenase. Synonyms: 8-(4-chlorophenylthio)adenosine-5'-O-monophosphate. Grades: ≥ 97 % by HPLC. CAS No. 78710-84-6. Molecular formula: C16H17ClN5O7PS. Mole weight: 489.83. | |
| 8-pCPT-cGMP | 8-pCPT-cGMP is a selective activator of cGMP-dependent protein kinase type I α and type II, as well as of cGMP-gated ion channels. It has higher membrane permeability and stability towards many phosphodiesterases. Synonyms: 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 51239-26-0. Molecular formula: C16H14ClN5O7PS · Na. Mole weight: 509.8. | |
| 8-pCPT-cGMP-AM | 8-pCPT-cGMP-AM is a precursor of 8-pCPT-cGMP, the PKG activator. 8-pCPT-cGMP is released after the metabolism of 8-pCPT-cGMP-AM by esterases. Synonyms: 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 97% by HPLC for mixture of isomers. CAS No. 272445-72-4. Molecular formula: C19H19ClN5O9PS. Mole weight: 559.9. | |
| 8-pHPT-2'-O-Me-cAMP | 8-pHPT-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It has superior lipophilicity, membrane permeability and PDE stability. Synonyms: 8- (4- Hydroxyphenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate , sodium salt. Grades: ≥ 98% by HPLC. CAS No. 612513-15-2. Molecular formula: C17H17N5O7PS · Na. Mole weight: 489.4. | |
| 8-PIP-cAMP | 8-PIP-cAMP is a selective cAMP analogue with a preference for site A of protein kinase A type I and for site B of type II. Compared to cAMP, it has superior stability and membrane permeability. Synonyms: 8- Piperidinoadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 31357-06-9. Molecular formula: C15H20N6O6P · Na. Mole weight: 434.3. | |
| 8-pMeOPT-2'-O-Me-cAMP | 8-pMeOPT-2'-O-Me-cAMP is a specific activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It is highly lipophilic, membrane-permeant and stable for PDE. Synonyms: 8- (4- Methoxyphenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 612513-16-3. Molecular formula: C18H19N5O7PS · Na. Mole weight: 503.4. | |
| 8-Styryl-dG CEP | 8-Styryl-dG CEP, an indispensable compound within the realm of biomedicine, assumes a pivotal role. It facilitates the creation of modified nucleosides and oligonucleotides, thus serving as a fundamental constituent. This compound's distinct structural attributes contribute significantly to drug development and therapies associated with DNA alterations, genetic manipulation, and gene suppression. CAS No. 1101864-12-3. Molecular formula: C51H59N8O7P. Mole weight: 927.04. | |
| 8-TEMPO-aminoadenosine Cyclic 3',5'-Monophosphate | 8-TEMPO-aminoadenosine Cyclic 3',5'-Monophosphate, a spin-labeled cyclic nucleotide used for the mapping of the cAMP site of protein kinase I from rabbit skeletal muscle. Synonyms: 4-[[6-Amino-9-(3,5-O-phosphinico-β-D-ribofuranosyl)-9H-purin-8-yl]amino]-2,2,6,6-tetramethyl-1-piperidinyloxy; 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, 1-Piperidinyloxy Deriv. CAS No. 54606-91-6. Molecular formula: C19H29N7O7P. Mole weight: 498.45. | |
| 8-Vinyl-dA CEP | 8-Vinyl-dA CEP is a cutting-edge biomedical compound, acting as a fundamental building block for custom nucleotides and oligonucleotides. CAS No. 851228-42-7. Molecular formula: C45H55N8O6P. Mole weight: 834.94. | |
| 9-(2',3',5'-Tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)6-methylpurine | 9-(2',3',5'-Tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)6-methylpurine is a vital compound exhibiting promising anti-viral properties and employed in the research of various viral diseases. With its unique chemical structure, It acts effectively against specific DNA and RNA viruses. Synonyms: 2'-C-Methyl-2',3',5'-tri-O-benzoyl-beta-D-6-methylpurine riboside; 6-Methyl-9-(2-C-methyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranosyl)purine. Grades: ≥95%. CAS No. 2095417-61-9. Molecular formula: C33H28N4O7. Mole weight: 592.60. | |
| 9-(2',3',5'-Tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)purine | 9-(2',3',5'-Tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)purine, an essential constituent utilized in the advancement of antiviral treatments, requires thorough investigation due to its significant implications in restraining the duplication of viral DNA. Hence, owing to its unparalleled configuration and biochemical characteristics, this compound exhibits substantial promise as a potential intervention against diverse viral infections. Moreover, its distinctive attributes may facilitate the targeting of drug-resistant variants, rendering it highly effective in combating a spectrum of viral maladies. Synonyms: 9-(2-C-Methyl-2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)purine; 9-(2',3',5'-Tri-O-benzoyl-2'C-methyl-b-D-ribofuranosyl)purine. Grades: ≥95%. CAS No. 2095417-45-9. Molecular formula: C32H26N4O7. Mole weight: 578.57. | |
| 9-(2',3',5'-tri-O-benzoyl-5'-(R)-C-Methyl-b-D-ribofuranosyl)-6-chloropurine | | |
| 9-(2'-C-methyl-b-D-ribofuranosyl)6-methylpurine | 9-(2'-C-methyl-b-D-ribofuranosyl)6-methylpurine is a bioactive compound used in biomedicine to treat various diseases. It exhibits potent antiviral activity against certain types of viruses by inhibiting their replication. Additionally, it has been investigated as a potential therapeutic agent for certain cancers and autoimmune diseases due to its ability to modulate immune responses. Synonyms: 2'-C-Methyl-beta-D-6-methylpurine riboside; 6-Methyl-9-(2-C-methyl-beta-D-ribofuranosyl)purine. Grades: ≥95%. CAS No. 2095417-06-2. Molecular formula: C12H16N4O4. Mole weight: 280.28. | |
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