BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 9-(2-C-Methyl-b-D-ribofuranosyl)purine | 9-(2-C-Methyl-b-D-ribofuranosyl)purine is a formidable nucleoside analogrenowned for its unwavering antiviral prowess. This exceptional compound operates as a potent nucleoside reverse transcriptase inhibitor, skillfully impeding viral replication via the artful blockade of the reverse transcriptase enzyme. Synonyms: 9-(2-C-Methyl-β-D-ribofuranosyl)purine; 9H-Purine, 9-(2-C-methyl-beta-D-ribofuranosyl)-; (2R,3R,4R,5R)-5-(Hydroxymethyl)-3-methyl-2-(9H-purin-9-yl)tetrahydrofuran-3,4-diol; 9-(2-C-Methyl-β-D-ribofuranosyl)-9H-purine. Grades: ≥95%. CAS No. 690269-86-4. Molecular formula: C11H14N4O4. Mole weight: 266.25. |  |
| 9-(2'-Deoxy-2'-fluoro-a-D-arabinofuranosyl)-9H-purin-6-amine | 9-(2'-Deoxy-2'-fluoro-α-D-arabinofuranosyl)-9H-purin-6-amine, a remarkable compound renowned for its potent antiviral properties, is extensively utilized within the esteemed biomedical sector. This exceptional therapeutic agent plays a pivotal role in combatting a plethora of viral infections triggered by the herpes simplex, varicella-zoster, and Epstein-Barr viruses. By impeding the replication of viral DNA, it actively thwarts the proliferation and recurrence of these notorious viral maladies. Synonyms: (2R,3R,4S,5S)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol. CAS No. 20187-82-0. Molecular formula: C10H12FN5O3. Mole weight: 269.23. | |
| 9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)hypoxantine | 9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)hypoxanthine, a remarkable antiviral agent and immunosuppressant, exhibits significant potential in combating viral infections such as herpes simplex virus and cytomegalovirus. A potent mechanism arises from its ability to impede viral DNA replication through chain termination, thereby obstructing viral DNA elongation. Synonyms: 2'-FANA-I. Grades: 97%. Molecular formula: C10H11FN4O4. Mole weight: 270.22. | |
| 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine | 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine, an extraordinary antiviral compound, exhibits immense potential in the biomedical field for combating viral infections induced by DNA viruses. Its exceptional efficacy stems from its ability to disrupt viral DNA synthesis, thereby impeding viral replication. This nucleoside analogue has demonstrated remarkable effectiveness against a multitude of viruses, including herpes simplex virus type 1 (HSV-1) and 2 (HSV-2), varicella-zoster virus (VZV), and Epstein-Barr virus (EBV). Synonyms: 2'-Deoxy-2'-fluoro-2-fluoroadenosine. Grades: 95%. CAS No. 147048-53-1. Molecular formula: C10H11F2N5O3. Mole weight: 287.23. | |
| 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine | 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine, an esteemed biomedical compound, stands as a paramount weapon in combatting egregious viral entities. Harnessing its remarkable antiviral potential, this compound seamlessly infiltrates viral life cycles by selectively impeding the replication of viral enzymes. Synonyms: 2'-Deoxy-2'-fluoroisoguanosine. Grades: 98%. Molecular formula: C10H12FN5O4. Mole weight: 285.24. | |
| 9-(2-Deoxy-2-fluoro-b-D-xylofuranosyl)-9H-purin-6-amine | 9-(2-Deoxy-2-fluoro-b-D-xylofuranosyl)-9H-purin-6-amine, commonly known as DFXY, is a remarkable antiviral agent employed for combatting specific viral infections, including hepatitis B and C. With its precise mechanism of action targeting the viral polymerase enzyme, DFXY displays remarkable effectiveness in hindering viral replication. Synonyms: (2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol; 9H-Purin-6-amine, 9-(2-deoxy-2-fluoro-β-D-xylofuranosyl)-. Grades: ≥97% by HPLC. CAS No. 123334-75-8. Molecular formula: C10H12FN5O3. Mole weight: 269.23. | |
| 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine | 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine is a cutting-edge biomedicine product used for the treatment of viral infections caused by Herpesviridae family, specifically herpes simplex viruses (HSV) and varicella-zoster virus (VZV). This compound exhibits potent antiviral activity by inhibiting viral DNA synthesis, thus preventing the replication of these viruses. Molecular formula: C35H36FN5O7. Mole weight: 657.69. | |
| 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite | The 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-beta-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite has been proven effective against cancer. Synonyms: 5'-O-DMT-2'-fluoro-N2-isobutyryl-2'-arabinofuranosyl-deoxyguanosine 3'-CE phosphoramidite; 2'-F-2'-ara-N2-ibu-dG phosphoramidite; Propanamide, N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methyl-; N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-fluoro-2'-arabinoguanosine-3'-CED-phosphoramidite; 9-{5-O-[Bis (4-methoxyphenyl) (phenyl)methyl]-3-O-[ (2-cyanoethoxy) (diisopropylamino)phosphino]-2-deoxy-2-fluoro-β -D-arabinofuranosyl}-2- (isobutyrylamino)-1, 9-dihydro-6H-purin-6-one. Grades: ≥97% by HPLC. CAS No. 1404463-20-2. Molecular formula: C44H53FN7O8P. Mole weight: 857.93. | |
| 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt | 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt, an esteemed asset within the biomedical sector, stands as a pivotal driving force for combating various ailments. Notably, this heralded innovation serves as an efficacious intervention for distinct malignancies, viral affections, and autoimmunity predicaments. Imbued with an unparalleled amalgamation and intricate architecture, it inherently offers targeted remedial measures, endowing it with unsurpassed potential within the realm of precision medicine. Molecular formula: C39H39FN5O10·C6H16N. Mole weight: 858.97. | |
| 9-(2'-Deoxy-5'-O-DMT-b-D-xylofuranosyl)adenine | 9-(2'-Deoxy-5'-O-DMT-b-D-xylofuranosyl)adenine, a remarkably potent nucleoside analogue, finds extensive application in the realm of biomedicine. It serves as a valuable asset in crafting antiviral medications, specifically designed to combat viral DNA polymerases. Its efficacy in addressing a wide range of viral afflictions, such as HIV, herpes simplex, and hepatitis B, exhibits tremendous potential. | |
| 9-(2'-Deoxy-b-D-xylofuranosyl)adenine | 9-(2'-Deoxy-b-D-xylofuranosyl)adenine, also referred to as 2'-deoxyadenosine, holds paramount importance in the realm of biomedical investigation. This nucleoside analog serves as a pivotal component in diverse applications, predominantly as an antiviral agent and as a constituent in cancer chemotherapy. Encouraging outcomes have been witnessed concerning its efficacy in combatting viral infections such as HIV and herpes. Synonyms: 9-(2-Deoxy-beta-D-threo-pentofuranosyl)adenine; 9H-Purin-6-amine, 9-(2-deoxy-beta-D-threo-pentofuranosyl)-; (2R,3R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 1-(2'-Deoxy-beta-threopentofuranosyl)adenine; 9-(2-Deoxy-β-D-threo-pentofuranosyl)-9H-purin-6-amine. Grades: ≥95%. CAS No. 13276-53-4. Molecular formula: C10H13N5O3. Mole weight: 251.24. | |
| 9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl-b-L-ribofuranosyl)-6-chloropurine | 9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl-b-L-ribofuranosyl)-6-chloropurine, an exceptional antiviral compound, exhibits remarkable potency against diverse viral infections. Its mechanism of action involves the precise targeting of vital viral enzymes and components crucial for the life cycle of the virus. Embracing a scientific approach, this product presents a highly prospective therapeutic alternative for susceptible viral-induced diseases, exhibiting substantial efficacy validated through preclinical and clinical investigations. Synonyms: 6-Chloro-9-[2-O-acetyl-5-O-(p-toluoyl)-3-azido-3-deoxy-beta-L-ribofuranosyl]-9H-purine. Grades: ≥95%. CAS No. 2095417-30-2. Molecular formula: C20H18ClN7O5. Mole weight: 471.85. | |
| 9- ( (2R, 4S, 5R) -4- ( (tert-Butyldimethylsilyl) oxy) -5- ( ( (tert-butyldimethylsilyl) oxy) methyl) tetrahydrofuran-2-yl) -9H-purin-6-amine | 9- ( (2R, 4S, 5R) -4- ( (tert-Butyldimethylsilyl) oxy) -5- ( ( (tert-butyldimethylsilyl) oxy) methyl) tetrahydrofuran-2-yl) -9H-purin-6-amine is a complex and multi-faceted compound that has found application in the research of purine metabolism as well as in the development of cancer treatments. Its capacity to impede cancer cell growth and proliferation via the manipulation of specific purine pathways is well documented. Moreover, studies have shown that it possesses immense potential in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's. Synonyms: Adenosine, 2'-deoxy-3',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-;3',5'-Bis-O-TBDMS-2'-Deoxyadenosine;3',5'-Bis-O-(tert-butyldimethylsilyl)-deoxyadenosine; 3',5'-Bis-O-(tert-butyldimethylsi lyl)-deoxyadenosine; 3',5'-O-Bis(tert-butyldimethylsilyl)-2'-deoxyadenosine; 3',5'-O-bis(tert-butyldimethylsiyl)-2'-deoxy-adenosine; 9-[ (2R, 4S, 5R)-4-[tert-butyl (dimethyl)silyl]oxy-5-[[tert-butyl (dimethyl)silyl]oxymethyl]oxolan-2-yl]purin-6-amine. Grades: 98%. CAS No. 51549-32-7. Molecular formula: C22H41N5O3Si2. Mole weight: 479.76. | |
| 9-(3',5'-Di-O-acetyl-2'-O-methyl-b-D-ribofuranosyl)-6-chloropurine | 6-Chloropurine (9-(3',5'-Di-O-acetyl-2'-O-methyl-b-D-ribofuranosyl)) is an exceptionally potent antiviral agent extensively employed for the therapeutic management of viral infections, specifically hepatitis B and C. Its mechanism of action involves profound interference with viral DNA or RNA synthesis, thereby effectively suppressing viral replication. Synonyms: 6-chloro-9-[3',5'-di-O-acetyl-2'-O-methyl-β-D-ribofuranosyl] purine; Acetic acid (2R,3R,4R,5R)-2-acetoxymethyl-5-(6-chloro-purin-9-yl)-4-methoxy-tetrahydro-furan-3-yl ester. CAS No. 194034-61-2. Molecular formula: C15H17ClN4O6. Mole weight: 384.77. | |
| 9- ( (3aR, 4R, 6R, 6aR) -2, 2-Dimethyl-6- ( (methylamino) methyl) tetrahydrofuro[3, 4-d][1, 3]dioxol-4-yl) -9H-purin-6-amine | 9- ( (3aR, 4R, 6R, 6aR) -2, 2-Dimethyl-6- ( (methylamino) methyl) tetrahydrofuro[3, 4-d][1, 3]dioxol-4-yl) -9H-purin-6-amine is a formidable and effective suppressor of adenosine kinases, utilized in the amelioration of malignancies and inflammatory disorders, in addition to assorted neurological ailments rooted in adenosine signaling. Its molecular configuration bears striking resemblance to adenosine, facilitating facile assimilation into cellular paths. This enables the thwarting of intracellular effects of adenosine, leading to beneficial outcomes. CAS No. 34245-49-3. Molecular formula: C14H20N6O3. Mole weight: 320.35. | |
| 9-(3'-Deoxy-3'-fluoro-b-D-ribofuranosyl)-6-[6-(4-methylpiperazinyl)pyridin-3-yl]purine | 9-(3'-Deoxy-3'-fluoro-b-D-ribofuranosyl)-6-[6-(4-methylpiperazinyl)pyridin-3-yl]purine is a pharmaceutical compound, showcasing remarkable promise in research of diverse viral infections and cancers. Synonyms: 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-methylpiperazinyl)pyridin-3-yl]purine; (2R,3S,4S,5R)-4-fluoro-5-(hydroxymethyl)-2-[6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]purin-9-yl]oxolan-3-ol. Grades: ≥95%. CAS No. 1612191-99-7. Molecular formula: C20H24FN7O3. Mole weight: 429.45. | |
| 9-(3'-O-Methyl-b-D-xylofuranosyl)adenine | | |
| 9-(5'-Methyl-b-D-ribofuranosyl)-6-chloropurine | 9-(5'-Methyl-b-D-ribofuranosyl)-6-chloropurine is an immensely powerful antiviral substance widely utilized in research of various pernicious viral infections, including hepatitis B and C, in conjunction with specific herpes strains. Synonyms: 6-Chloropurine-9-(5-methyl-beta-D-ribofuranoside). Molecular formula: C11H13ClN4O5. Mole weight: 316.7. | |
| 9-(b-D-Arabinofuranosyl)-8-chloroadenine | 9-(b-D-Arabinofuranosyl)-8-chloroadenine is a highly efficacious antiviral pharmaceutical, exhibiting remarkable potential in research of viral infections originating from the herpes family of viruses. Harnessing its exceptional inhibitory properties against viral DNA enhancement, this compound profoundly impedes viral multiplication. Synonyms: 8-Chloro-arabinoadenosine; (2R,3S,4S,5R)-2-(6-amino-8-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 769872-68-6. Molecular formula: C10H12ClN5O4. Mole weight: 301.69. | |
| 9-(b-D-Arabinofuranosyl)isoguanine | 9-(b-D-Arabinofuranosyl)isoguanine, a biomedical marvel, stands tall as a potent weapon against a variety of viral infections. Operating as an exceptional antiviral agent, it exerts its therapeutic might by impeding the replication of viral DNA/RNA. In the realms of herpetic maladies and the notorious cytomegalovirus, this prodigious product thrives as a guardian of wellness. Synonyms: Arabinosyl-isoguanine. Grades: 98%. CAS No. 38819-11-3. Molecular formula: C10H13N5O5. Mole weight: 283.25. | |
| 9-(b-D-Arabinofuranosyl)-N6-benzoyladenine | 9-(b-D-Arabinofuranosyl)-N6-benzoyladenine, a highly potent antiviral agent widely employed in the management of viral infections, exhibits immense potential in countering viral diseases like influenza and herpes. Its remarkable ability to impede viral replication has unveiled promising outcomes. This efficacy stems from its unique mode of action, which involves obstructing a crucial viral enzyme involved in the synthesis of viral DNA. Synonyms: N6-Benzoyl-9-β-D-arabinofuranosyladenine; N6-Benzoylarabinoadenosine; N6-Benzoyl-ara-adenosine; 9-(b-D-Arabinofuranosyl)-N6-benzoyl-D-adenine; N-Benzoyl-9-beta-D-arabinofuranosyl-9H-purine-6-amine; N6-Bz-2'-ara-rA; 9-(β-D-Arabinofuranosyl)-N-benzoyl-9H-purin-6-amine. Grades: ≥95%. CAS No. 79896-97-2. Molecular formula: C17H17N5O5. Mole weight: 371.35. | |
| 9-(b-L-Arabinofuranosyl)guanine | 9-(b-L-Arabinofuranosyl)guanine, a profoundly powerful antiviral agent, finds application in combatting an array of viral afflictions such as herpes simplex and herpes zoster. Its mechanism entails impeding viral DNA replication, impeding the proliferation and subsequent harm inflicted by the virus. Grades: 95%. CAS No. 469887-93-2. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
| 9-Dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 | 9-Dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 is the major DNA adduct formed by the liver carcinogen aflatoxin B1. Synonyms: 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6, 9-dihydro-7-(1, 2, 3, 6a, 8, 9, 9a, 11-octahydro-9-hydroxy-4-methoxy-1, 11-dioxocyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h][1]benzopyran-8-yl)-6-oxo-1H-purinium; AFB1-N7-Gua; Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran, 1H-purinium deriv. CAS No. 64585-66-6. Molecular formula: C27H26N5O11. Mole weight: 596.52. | |
| 9-Fluorenylmethyl Carbamate | Reagent for the introduction of the Fmoc-group. Synonyms: Fmoc-NH2; Fmoc-amide; 9-Fluorenylmethyl carbamate; N-(9-Fluorenylmethoxycarbonyl)amide; ACMC-209pum; fluoren-9-ylmethyl aminooate; KSC448A6B; SCHEMBL113270; SCHEMBL2192202. Grades: ≥ 99 % (HPLC). CAS No. 84418-43-9. Molecular formula: C15H13NO2. Mole weight: 239.27. | |
| 9H-?Purin-?2-?amine, 9-? [2-? O-? acetyl-? 3-? azido-? 3-? deoxy-? 5-? O-? (4-? methylbenzoyl) ? -? β -? D-? ribofuranosyl] ? -? 6-? chloro-? N-? [ (4-? methoxyphenyl) ? diphenylmethyl] ? - | 9H-Purin-2-amine, 9-[2-O-acetyl-3-azido-3-deoxy-5-O-(4-methylbenzoyl)-β-D-ribofuranosyl]-6-chloro-N-[(4-methoxyphenyl)diphenylmethyl] is a novel biomedical compound utilized in the research of various viral infections and certain types of cancer. It exhibits potent antiviral and anticancer properties, targeting specific pathways involved in viral replication and cancer progression. CAS No. 2299278-18-3. Molecular formula: C40H35ClN8O6. Mole weight: 759.21. | |
| [Aba5-14] BTD-2 | [Aba5-14] BTD-2 is an antimicrobial peptide produced by Synthetic construct. It has antibacterial activity. Synonyms: Gly-Val-Cys-Arg-X-Val-Cys-Arg-Arg-Gly-Val-Cys-Arg-X-Val-Cys-Arg-Arg. Grades: >98%. | |
| [Ala107]-MBP (104-118) | [Ala107]-MBP (104-118) is a non-competitive inhibitor of PKC with IC50 value of 46-145 mM. It is a synthetic peptide analog of bovine myelin basic protein (MBP). Synonyms: [Ala107]-Myelin Basic Protein (104-118). Grades: >98%. CAS No. 99026-77-4. Molecular formula: C67H104N20O19. Mole weight: 1493.68. | |
| [Ala113]-MBP (104-118) | [Ala113]-MBP (104-118) is a non-competitive inhibitor of PKC with IC50 value of 46-145 mM. It is a synthetic peptide analog of bovine myelin basic protein (MBP). Synonyms: [Ala113]-Myelin Basic Protein (104-118). Grades: >98%. CAS No. 99026-78-5. Molecular formula: C67H104N20O19. Mole weight: 1493.68. | |
| [Ala1,3,11,15]-Endothelin 1 | [Ala1,3,11,15]-Endothelin is a selective ETB endothelin receptor agonist (IC50 = 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors, respectively). Synonyms: [Ala1,3,11,15]-Endothelin 1. CAS No. 121204-87-3. Molecular formula: C109H163N25O32S. Mole weight: 2367.67. | |
| α-2'-Deoxy Zebularine | α-2'-Deoxy Zebularine is the α-anomer of β-2'-Deoxy Zebularine; a Zebularine metabolite which can be used as an inhibitor of human deoxycytidylate deaminase. Synonyms: 1-(2-Deoxy-α-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone. CAS No. 68780-64-3. Molecular formula: C9H12N2O4. Mole weight: 212.2. | |
| α-Clofarabine | α-Clofarabine is a second generation purine nucleoside analog; antimetabolite that inhibits DNA synthesis and resists deamination by adenosine deaminase. Antineoplastic. Synonyms: 2-Chloro-9-(2-deoxy-2-fluoro-α-D-arabinofuranosyl)-9H-purin-6-amine. CAS No. 491594-60-6. Molecular formula: C10H11ClFN5O3. Mole weight: 303.68. | |
| α-Conotoxin AuIB | α-Conotoxin AuIB is a selective antagonist of α3β4 nicotinic acetylcholine receptors. It shows > 100-fold selectivity over other receptor subunit combinations. Synonyms: alfa-Conotoxin AuIB; Gccsyppcfa tnpdc. CAS No. 216299-21-7. Molecular formula: C65H89N17O21S4. Mole weight: 1572.76. | |
| α-Conotoxin EI | α-Conotoxin EI is a selective antagonist of neuromuscular nicotinic receptors α1β1γ&delta. It shows selectivity for α/δ sites over α/γ sites in Torpedo. Synonyms: RDXCCYHPTC NMSNPQIC; 170663-33-9; alpha-Conotoxin EI; ALPHA-CONOTOXIN EL; ?-Conotoxin EI; PD079395. Grades: >96%. CAS No. 170663-33-9. Molecular formula: C83H125N27O27S5. Mole weight: 2093.4. | |
| α-Conotoxin GI | α-conotoxin GI (alpha-conotoxin GI) is a conopeptide that has been isolated from the venom of the cone snail Conus geographus. α-conotoxin GI is a competitive antagonist of the muscle-type nicotinic acetylcholine receptors (nAChR) such as α-conotoxin MI or d-Turbocurarine. Synonyms: Conotoxin GI; Conotoxin G I; alpha-Conotoxin G I; Myotoxin from Conus geographus venom; alpha-Conotoxin G I (reduced), cyclic (2-7),(3-13)-bis(disulfide). Grades: > 95 %. CAS No. 76862-65-2. Molecular formula: C55H80N20O18S4. Mole weight: 1437.61. | |
| α-Conotoxin MII | α-Conotoxin MII is a nicotinic acetylcholine receptor antagonist. It is highly potent, selective and competitive for α3β2 subunit. Its IC50 value is 0.5-3.5 nM at α3β2 expressed in Xenopus oocytes. It also potently prevents β3-containing neuronal nicotinic receptors. Synonyms: Alpha-Conotoxin MII; H-Gly-Cys(1)-Cys(2)-Ser-Asn-Pro-Val-Cys(1)-His-Leu-Glu-His-Ser-Asn-Leu-Cys(2)-NH2; glycyl-L-cysteinyl-L-cysteinyl-L-seryl-L-asparagyl-L-prolyl-L-valyl-L-cysteinyl-L-histidyl-L-leucyl-L-alpha-glutamyl-L-histidyl-L-seryl-L-asparagyl-L-leucyl-L-cysteinamide (2->8),(3->16)-bis(disulfide). Grades: ≥95%. CAS No. 175735-93-0. Molecular formula: C67H103N23O22S4. Mole weight: 1710.99. | |
| α-Conotoxin PnIA | α-Conotoxin PnIA is a nicotinic acetylcholine receptor antagonist. It is selective for α3β2 nAChR receptors with IC50 value of 9.56 nM. It was sold under license for Cognetix for research purposes only. Synonyms: alpha-conotoxin PnIA; 705300-84-1; A-CONOTOXIN PNIACHEMBL4443205GTPL3982. Grades: >97%. CAS No. 705300-84-1. Molecular formula: C65H95N19O22S4. Mole weight: 1622.82. | |
| α-Sofosbuvir Desphosphate | As a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate, α-Sofosbuvir Desphosphate is a possible metabolite of Sofosbuvir is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| α-Tocopherol-TEG Phosphoramidite | α-Tocopherol-TEG Phosphoramidite, a potent reagent utilized in the synthesis of modified nucleotides, boasts antiviral activity against RNA viruses including the ever-dreaded hepatitis C virus (HCV). Application of this reagent results in superior stability, potency, and delivery of modified nucleotides to the targeted cells. Synonyms: 1-Dimethoxytrityloxy-3-O-[(9-DL-α-tocopheryl)-triethyleneglycol-1-yl]-glyceryl-2-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C68H103N2O10P. Mole weight: 1139.56. | |
| (Amino-3,3-Me2-BChept-2-yl)acetic acid HCl(R,S,S) | Synonyms: [(1R,2S,4S)-2-amino-3,3-dimethylbicyclo[2.2.1]hept-2-yl]acetic acid hydrochloride. CAS No. 1335031-66-7. Molecular formula: C11H19NO2·HCl. Mole weight: 233.73. | |
| (Amino-3,3-Me2-BChept-2-yl)acetic acid(R,S,S) | Synonyms: [(1R,2S,4S)-2-amino-3,3-dimethylbicyclo[2.2.1]hept-2-yl]acetic acid. Molecular formula: C11H19NO2. Mole weight: 197.27. | |
| (Amino-6,6-Me2-BChept-2-yl)acetic acid HCl(R,S,S) | Synonyms: [(1R,2S,5S)-2-amino-6,6-dimethylbicyclo[3.1.1]hept-2-yl]acetic acid hydrochloride. CAS No. 1335031-82-7. Molecular formula: C11H19NO2·HCl. Mole weight: 233.73. | |
| (Amino-6,6-Me2-BChept-2-yl)acetic acid(R,S,S) | Synonyms: [(1R,2S,5S)-2-amino-6,6-dimethylbicyclo[3.1.1]hept-2-yl]acetic acid. CAS No. 1335093-14-5. Molecular formula: C11H19NO2. Mole weight: 197.27. | |
| ?Aminocaproic acid | Aminocaproic acid is a derivative and analogue of the amino acid lysine, which makes it an effective inhibitor for enzymes that bind that particular residue. Such enzymes include proteolytic enzymes like plasmin, the enzyme responsible for fibrinolysis. Uses: Antifibrinolytic agents. Synonyms: Aminocaproic acid; NSC 400230; NSC-400230; NSC400230. Grades: >98%. CAS No. 60-32-2. Molecular formula: C6H13NO2. Mole weight: 131.17. | |
| B2RP-ERa | B2RP-ERa is an antimicrobial peptide produced by Hylarana erythraea, Asia. It has antibacterial and antifungal activity. Synonyms: brevinin-2-related peptide-ERa (B2RP-ERa); H.erythraea B2RP; Gly-Val-Ile-Lys-Ser-Val-Leu-Lys-Gly-Val-Ala-Lys-Thr-Val-Ala-Leu-Gly-Met-Leu-NH2. Grades: ≥96%. Molecular formula: C86H159N23O21S. Mole weight: 1883.42. | |
| Bac4 (cattle) | Bac4 is an extended-helical cathelicidin produced by Bos primigenius, cattle. It has antimicrobial activity. Synonyms: Arg-Arg-Leu-His-Pro-Gln-His-Gln-Arg-Phe-Pro-Arg-Glu-Arg-Pro-Trp-Pro-Lys-Pro-Leu-Ser-Leu-Pro-Leu-Pro-Arg-Pro-Gly-Pro-Arg-Pro-Trp-Pro-Lys-Pro-Leu; Bac4. Grades: 98%. | |
| Bac 5 | Bac 5 is an antimicrobial peptide isolated from large granules of bovine neutrophils. It exhibits antibacterial activity against gram-negative bacteria. Synonyms: H-Arg-Phe-Arg-Pro-Pro-Ile-Arg-Arg-Pro-Pro-Ile-Arg-Pro-Pro-Phe-Tyr-Pro-Pro-Phe-Arg-Pro-Pro-Ile-Arg-Pro-Pro-Ile-Phe-Pro-Pro-Ile-Arg-Pro-Pro-Phe-Arg-Pro-Pro-Leu-Gly-Pro-Phe-Pro-OH; Bactenecin 5; PR-42; Cathelicidin-2. Grades: >98%. | |
| BacCH91 | BacCH91 is an antimicrobial peptide produced by Staphylococcus aureus CH-91. It has antibacterial activity. Synonyms: BacCH91 (Bacteriocin). Grades: >98%. | |
| Bactenecin | Bactenecin is an antibacterial peptide isolated from Bos taurus. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Cathelicidin-1; Cyclic dodecapeptide precursor; H-Arg-Leu-Cys(1)-Arg-Ile-Val-Val-Ile-Arg-Val-Cys(1)-Arg-OH. Molecular formula: C63H118N24O13S2. Mole weight: 1483.9. | |
| Bactenecin-1 (sheep) | Bactenecin-1 is an antimicrobial peptide produced by Ovis aries (Sheep). It has antibacterial activity against gram-negative bacteria and gram-positive bacteria. Synonyms: Cathelicidin-1; Bac1; Cyclic dodecapeptide; Arg-Ile-Cys-Arg-Ile-Ile-Phe-Leu-Arg-Val-Cys-Arg (Disulfide bridge: Cys3-Cys11). Grades: >95%. Molecular formula: C68H120N24O13S2. Mole weight: 1545.98. | |
| Bactenecin 5 (bovine) | Bactenecin 5 (bovine) is an antimicrobial peptide isolated from Bos taurus (bovine). It has antibacterial activity. Synonyms: Arg-Phe-Arg-Pro-Pro-Ile-Arg-Arg-Pro-Pro-Ile-Arg-Pro-Pro-Phe-Tyr-Pro-Pro-Phe-Arg-Pro-Pro-Ile-Arg-Pro-Pro-Ile-Phe-Pro-Pro-Ile-Arg-Pro-Pro-Phe-Arg-Pro-Pro-Leu-Arg-Phe-Pro. Grades: >98%. | |
| Bactenecin 7 | Bactenecin 7 is an antimicrobial peptide isolated from Bovine neutrophils and Bos taurus. It has antibacterial activity against gram-negative bacteria. Synonyms: bac 7, Pro-rich; bovine cathelicidin; Arg-Arg-Ile-Arg-Pro-Arg-Pro-Pro-Arg-Leu-Pro-Arg-Pro-Arg-Pro-Arg-Pro-Leu-Pro-Phe-Pro-Arg-Pro-Gly-Pro-Arg-Pro-Ile-Pro-Arg-Pro-Leu-Pro-Phe-Pro-Arg-Pro-Gly-Pro-Arg-Pro-Ile-Pro-Arg-Pro-Leu-Pro-Phe-Pro-Arg-Pro-Gly-Pro-Arg-Pro-Ile-Pro-Arg-Pro-Leu. Grades: >98%. | |
| Bactericidin B-2 | Bactericidin B-2 is an antimicrobial peptide produced by Manduca sexta (Tobacco hornworm). It has antibacterial activity. Synonyms: Cecropin-like peptide B-2; Trp-Asn-Pro-Phe-Lys-Glu-Leu-Glu-Arg-Ala-Gly-Gln-Arg-Val-Arg-Asp-Ala-Val-Ile-Ser-Ala-Ala-Pro-Ala-Val-Ala-Thr-Val-Gly-Gln-Ala-Ala-Ala-Ile-Ala-Arg-Gly. Grades: ≥97%. Molecular formula: C169H276N54O49. Mole weight: 3848.38. | |
| Bacteriocin acidocin 8912 | Bacteriocin acidocin 8912 is an antimicrobial peptide found in Lactobacillus acidophilus TK8912. It has bactericidal effect on sensitive cells but no bacteriolytic effect. Synonyms: Acidocin 8912 (Bacteriocin); acdT; Lys-Thr-His-Tyr-Pro-Thr-Asn-Ala-Trp-Lys-Ser-Leu-Trp-Lys-Gly-Phe-Trp-Glu-Ser-Leu-Arg-Tyr-Thr-Asp-Gly-Phe. Grades: >96%. CAS No. 142106-05-6. Molecular formula: C154H212N38O39. Mole weight: 3219.61. | |
| Bacteriocin bavaricin-MN | Bacteriocin bavaricin-MN is an antimicrobial peptide found in Lactobacillus sakei. It has antimicrobial activity. Synonyms: Bavaricin-MN (Bacteriocin); Thr-Lys-Tyr-Tyr-Gly-Asn-Gly-Val-Tyr-Cys-Asn-Ser-Lys-Lys-Cys-Trp-Val-Asp-Trp-Gly-Gln-Ala-Ala-Gly-Gly-Ile-Gly-Gln-Thr-Val-Val-X-Gly-Trp-Leu-Gly-Gly-Ala-Ile-Pro-Gly-Lys. Grades: >85%. CAS No. 144376-92-1. | |
| Bacteriocin curvacin-A | Bacteriocin curvacin-A is an antimicrobial peptide found in Lactobacillus curvatus LTH1174. It has antibacterial activity. It inhibits closely related Lactobacilli, Listeria monocytogenes and ivanovvi, Enterococcus faecalis, Carnobacterium sp and Brocothrix thermosphacta. Synonyms: Curvacin A (Bacteriocin); curA; Ala-Arg-Ser-Tyr-Gly-Asn-Gly-Val-Tyr-Cys-Asn-Asn-Lys-Lys-Cys-Trp-Val-Asn-Arg-Gly-Glu-Ala-Thr-Gln-Ser-Ile-Ile-Gly-Gly-Met-Ile-Ser-Gly-Trp-Ala-Ser-Gly-Leu-Ala-Gly-Met. Grades: >85%. CAS No. 146239-44-3. Molecular formula: C184H288N56O56S4. Mole weight: 4308.89. | |
| Bacteriocin curvaticin FS47 | Bacteriocin curvaticin FS47 is an antimicrobial peptide found in Lactobacillus curvatus FS47. It has an inhibitory effect on Listeria monocytogenes, Lactobacillus, Pediococcus, Enterococcus, and Bacillus spp. Synonyms: Curvaticin FS47 (Bacteriocin); Tyr-Thr-Ala-Lys-Gln-Cys-Leu-Gln-Ala-Ile-Gly-Ser-Cys-Gly-Ile-Ala-Gly-Thr-Gly-Ala-Gly-Ala-Ala-Gly-Gly-Pro-Ala-Gly-Ala-Phe-Val-Gly-Ala-X-Val-Val-X-Ile. Grades: >85%. CAS No. 157243-19-1. | |
| Bacteriocin E50-52 | Bacteriocin E50-52 is an antimicrobial peptide found in Enterococcus faecium (Streptococcus faecium). It has antibacterial activity against the Gram-negative bacteria C.jejuni, Y.enterocolitica and Y.pseudotuberculosis, and the Gram-positive bacteria S.aureus, S.epidermidis, L.monocytogenes and Listeria spp. Synonyms: Thr-Thr-Lys-Asn-Tyr-Gly-Asn-Gly-Val-Cys-Asn-Ser-Val-Asn-Trp-Cys-Gln-Cys-Gly-Asn-Val-Trp-Ala-Ser-Cys-Asn-Leu-Ala-Thr-Gly-Cys-Ala-Ala-Trp-Leu-Cys-Lys-Leu-Ala. Grades: >85%. CAS No. 1016899-89-0. | |
| Bacteriocin hiracin-JM79 | Bacteriocin hiracin-JM79 is an antimicrobial peptide found in Enterococcus hirae DCH5. It has antibacterial activity against the Gram-positive bacteria: Listeria, Enterococcus, Propionibacterim, Staphylococcus and some strains of Clostridium, Lactobacillus and Pediococcus, and no antibacterial activity against Gram-negative bacteria. Synonyms: HirJM79 (Bacteriocin); Hiracin-JM79 (Bacteriocin); Ala-Thr-Tyr-Tyr-Gly-Asn-Gly-Leu-Tyr-Cys-Asn-Lys-Glu-Lys-Cys-Trp-Val-Asp-Trp-Asn-Gln-Ala-Lys-Gly-Glu-Ile-Gly-Lys-Ile-Ile-Val-Asn-Gly-Trp-Val-Asn-His-Gly-Pro-Trp-Ala-Pro-Arg-Arg. Grades: >85%. CAS No. 1030628-30-8. Molecular formula: C232H340N66O61S2. Mole weight: 5093.78. | |
| Bacteriocin lactocin-S | Bacteriocin lactocin-S is an antimicrobial peptide produced by Lactobacillus sakei L45. It has antibacterial activity and inhibits the growth of selected species of the genera Lactobacillus, Pedicoccus, and Leuconostoc. It contains at least two lanthionines, which are probably formed between the serine in position 23 and the cysteine in position 28, and between the serine in position 32 and the cysteine in position 37. Synonyms: Ser-Thr-Pro-Val-Leu-Ala-Ser-Val-Ala-Val-Ser-Met-Glu-Leu-Leu-Pro-Thr-Ala-Ser-Val-Leu-Tyr-Ser-Asp-Val-Ala-Gly-Cys-Phe-Lys-Tyr-Ser-Ala-Lys-His-His-Cys; lasA; Lactocin S (Bacteriocin). Grades: >85%. CAS No. 125387-34-0. | |
| Bacteriocin leucocin-A | Bacteriocin leucocin-A is an antimicrobial peptide produced by Leuconostoc gelidum UAL187. It has antibacterial activity against Gram-positive bacteria: Lactic acid bacteria, Listeria monocytogenes. Synonyms: lcnA; Leucocin A-UAL 187; Leu A; Leucocin-A; Leucocin A-TA33a; Leucocin A-QU15; Lys-Tyr-Tyr-Gly-Asn-Gly-Val-His-Cys-Thr-Lys-Ser-Gly-Cys-Ser-Val-Asn-Trp-Gly-Glu-Ala-Phe-Ser-Ala-Gly-Val-His-Arg-Leu-Ala-Asn-Gly-Gly-Asn-Gly-Phe-Trp (Disulfide bridge: Cys9-Cys14). Grades: >85%. CAS No. 139069-78-6. Molecular formula: C174H246N52O50S2. Mole weight: 3930.32. | |
| Bacteriocin leucocin C | Bacteriocin leucocin C is an antimicrobial peptide produced by Leuconostoc mesenteroides. It has antibacterial activity against a wide spectrum of lactic acid bacteria. Synonyms: Leucocin C; Leu C; Lys-Asn-Tyr-Gly-Asn-Gly-Val-His-Cys-Thr-Lys-Lys-Gly-Cys-Ser-Val-Asp-Trp-Gly-Tyr-Ala-Trp-Thr-Asn-Ile-Ala-Asn-Asn-Ser-Val-Met-Asn-Gly-Leu-Thr-Gly-Gly-Asn-Ala-Gly-Trp-His-Asn. Grades: >85%. CAS No. 386254-62-2. Molecular formula: C198H291N61O61S3. Mole weight: 4598.04. | |
| Bacteriocin SRCAM 37 | Bacteriocin SRCAM 37 is an antimicrobial peptide produced by Paenibacillus polymyxa (Bacillus polymyxa). It has antibacterial activity against Gram-positive bacteria: Clostridium jejuni. Synonyms: Phe-Val-Tyr-Gly-Asn-Gly-Val-Thr-Ser-Ile-Leu-Val-Gln-Ala-Gln-Phe-Leu-Val-Asn-Gly-Gln-Arg-Arg-Phe-Phe-Tyr-Thr-Pro-Asp-Lys. Grades: >97%. Molecular formula: C162H242N42O43. Mole weight: 3465.96. | |
| Bacteriocin SRCAM 602 | Bacteriocin SRCAM 602 is an antimicrobial peptide produced by Paenibacillus polymyxa (Bacillus polymyxa). It has antibacterial activity against Gram-positive bacteria: Clostridium jejuni. Synonyms: Ala-Thr-Tyr-Tyr-Gly-Asn-Gly-Leu-Tyr-Cys-Asn-Lys-Gln-Lys-His-Tyr-Thr-Trp-Val-Asp-Trp-Asn-Lys-Ala-Ser-Arg-Glu-Ile-Gly-Lys-Ile-Thr-Val-Asn-Gly-Trp-Val-Gln-His. Grades: ≥96%. Molecular formula: C211H307N59O58S. Mole weight: 4630.19. | |
| Bacteriocin sublancin-168 | Bacteriocin sublancin-168 is an antimicrobial peptide produced by Bacillus phage SPbeta (Bacillus phage SPBc2, Bacteriophage SP-beta). It has antibacterial activity against Gram-positive bacteria. It is an unusual S-linked glycopeptide with a glucose (Glc) moiety β-linked to cysteine-22 (Cys-22). Synonyms: Sublancin-168 (Bacteriocin); Gly-Leu-Gly-Lys-Ala-Gln-Cys-Ala-Ala-Leu-Trp-Leu-Gln-Cys-Ala-Ser-Gly-Gly-Thr-Ile-Gly-Cys(Glc)-Gly-Gly-Gly-Ala-Val-Ala-Cys-Gln-Asn-Tyr-Arg-Gln-Phe-Cys-Arg (Disulfide bridge: Cys7-Cys36, Cys14-Cys29). Grades: >85%. | |
| Bacteriocin thuricin-S | Bacteriocin thuricin-S is an antimicrobial peptide produced by Bacillus thuringiensis subsp. entomocidus. It has antibacterial activity against Gram-positive bacteria L.monocytogenes, B.subtilis and other Bacillus, E.cloacae, L.acidophilus, L.lactis, P.acidilactici, S.thermophilus, and several Gram-negative bacteria including S.cholerae, S.flexneri and P.aeruginosa. Synonyms: Thuricin-S (Bacteriocin); DWTAWSALVAAACSVELL. Grades: >85%. | |
| Bactofencin A | Bactofencin A is an antimicrobial peptide produced by Lactobacillus salivarius DPC6502. It has antibacterial activity against Listeria monocytogenes and Staphylococcus aureus. Synonyms: Lys-Arg-Lys-Lys-His-Arg-Cys-Arg-Val-Tyr-Asn-Asn-Gly-Met-Pro-Thr-Gly-Met-Tyr-Arg-Trp-Cys (Disulfide bridge: Cys7-Cys22). Grades: >98%. Molecular formula: C119H188N42O28S4. Mole weight: 2783.32. | |
| Bactrocerin-1 | Bactrocerin-1 is an antimicrobial peptide produced by Bactrocera dorsalis. It has a very broad spectrum of anti-microbial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. Synonyms: Val-Gly-Lys-Thr-Trp-Ile-Lys-Val-Ile-Arg-Gly-Ile-Gly-Lys-Ser-Lys-Ile-Lys-Trp-Gln; L-valylglycyl-L-lysyl-L-threonyl-L-tryptophyl-L-isoleucyl-L-lysyl-L-valyl-L-isoleucyl-L-arginylglycyl-L-isoleucylglycyl-L-lysyl-L-seryl-L-lysyl-L-isoleucyl-L-lysyl-L-tryptophyl-L-glutamine. Grades: 96%. CAS No. 1100646-39-6. Molecular formula: C110H185N31O24. Mole weight: 2325.87. | |
| Bak BH3 | Bak BH3, derived from the BH3 domain of Bak, was found to antagonize the protective effects of microinjected Bcl-xL in a-Fas-treated HeLa cells, whereas a mutant Bak BH3 peptide that no longer binds Bcl-xL was inactive. Synonyms: BakBH3; Bak-BH3; H-Gly-Gln-Val-Gly-Arg-Gln-Leu-Ala-Ile-Ile-Gly-Asp-Asp-Ile-Asn-Arg-OH; glycyl-L-glutaminyl-L-valyl-glycyl-L-arginyl-L-glutaminyl-L-leucyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-alpha-aspartyl-L-alpha-aspartyl-L-isoleucyl-L-asparagyl-L-arginine. Grades: ≥95%. Molecular formula: C72H125N25O24. Mole weight: 1724.95. | |
| [bAla8]-Neurokinin A (4-10) | An agonist of neurokinin 2 (NK2) receptor. Synonyms: MEN 10210; H-Asp-Ser-Phe-Val-bAla-Leu-Met-NH2; DSFVXLM; L-alpha-aspartyl-L-seryl-L-phenylalanyl-L-valyl-beta-alanyl-L-leucyl-L-methioninamide. Grades: ≥95%. CAS No. 122063-01-8. Molecular formula: C35H56N8O10S. Mole weight: 780.93. | |
| BAM-22P | BAM 22P is a potent endogenous agonist peptide for sensory neuron specific receptor (SNSR) (EC50 = 13 and 16 nM for human SNSR3 and SNSR4, respectively). BAM 22P is also a potent opioid agonist (IC50 = 1.3 nM in guinea pig ileum preparation) displaying opioid- and non-opioid receptor mediated antinociceptive effects in vivo. Synonyms: Bovine adrenal medulla-22P; Bam 22P; H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-methionyl-L-arginyl-L-arginyl-L-valyl-glycyl-L-arginyl-L-prolyl-L-alpha-glutamyl-L-tryptophyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-arginyl-L-tyrosyl-glycine. Grades: ≥95%. CAS No. 76622-26-9. Molecular formula: C130H184N38O31S2. Mole weight: 2839.22. | |
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