BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 5'-DMT-7-deaza-2'-deoxyguanosine (N-iBu) | 5'-DMT-7-deaza-2'-deoxyguanosine (N-iBu): a compound integral to the advancement of antiviral medications against hepatitis B and C. Its exceptional nucleoside analog characteristics enable the inhibition of viral DNA synthesis, inducing viral DNA base-pairing dysfunction, thereby proving efficacious for antiviral treatments. This compound also uniquely supports the study of DNA-protein interactions through its exceptional structural qualities. Grade: ≥ 98% by HPLC. Molecular formula: C36H38N4O7. Mole weight: 638.71. |  |
| 5'-DMT-7-deaza-2'-deoxyinosine | 5-DMT-7-deaza-2-deoxyinosine, a nucleoside analogue utilized to suppress the replication of viral DNA, exhibits potent efficacy against viruses such as herpes simplex virus and cytomegalovirus by interfering with the normal function of viral DNA polymerase. Its inhibitory action cripples the virus from proliferating, showcasing its unique ability to hinder viral replication. Grade: ≥ 98% by HPLC. Molecular formula: C32H31N3O6. Mole weight: 553.61. | |
| 5'-DMT-8-bromo-2'-deoxyadenosine (N-Bz) | N-Bz, or 5'-DMT-8-bromo-2'-deoxyadenosine, is a nucleoside analog that exhibits exciting antiviral properties against herpes viruses. Emerging evidence showcases its ability to suppress viral replication via the targeted inhibition of viral DNA polymerase enzymes. Such attributes present an enticing avenue toward treating herpes virus infections, potentially reducing their debilitating effects. Grade: ≥ 98% by HPLC. Molecular formula: C38H34BrN5O6. Mole weight: 736.61. | |
| 5'-DMT-8-bromo-2'-deoxyadenosine (N/N-dibutylformamidine) | 5'-DMT-8-bromo-2'-deoxyadenosine (N/N-dibutylformamidine) is an invaluable compound with sector, showcasing inhibitory efficacy in studying diverse ailments, encompassing viral infections and cancers. Grade: ≥ 98% by HPLC. Molecular formula: C40H47BrN6O5. Mole weight: 771.74. | |
| 5'-DMT-8-bromo-2'-deoxyguanosine (N-iBu) | 5'-DMT-8-bromo-2'-deoxyguanosine (N-iBu) is a crucial intermediary compound that is frequently harnessed in the manufacture of nucleoside analogues meant for treating viral infections, particularly hepatitis B and C. However, it is not just another run-of-the-mill small molecule. Indeed, researchers and practitioners alike have come to recognize it for its unique utility as a scientific tool for investigating nucleoside metabolism as well as drug resistance mechanisms. Grade: ≥ 98% by HPLC. Molecular formula: C35H36BrN5O7. Mole weight: 718.59. | |
| 5'-DMT-8-bromo-adenosine (N/N-dibutylformamidine) | 5'-DMT-8-bromo-adenosine (N/N-dibutylformamidine), a chemical compound extensively employed in biomedical research, is a highly promising modulator of adenosine receptors offering potential applications as an effective anti-cancer therapeutic in inhibiting cancer cell growth. Furthermore, current studies suggest that this compound could be a viable option to treat various neurological disorders including Parkinson's disease. Its marked effectiveness gives hope to further developments in the field of treating complex diseases. Grade: ≥ 98% by HPLC. Molecular formula: C40H47BrN6O6. Mole weight: 787.74. | |
| 5'-DMT-adenosine (N-Bz) | 5'-DMT-adenosine (N-Bz) emerges as a remarkably robust and focused activator, exhibiting profound selectivity towards the adenosine A1 receptor. Its strong affinity has garnered significant scientific interest in comprehending the intricate involvement of adenosine receptors across diverse physiological spectrums. Grade: ≥ 98% by HPLC. Molecular formula: C38H35N5O7. Mole weight: 673.71. | |
| 5'-DMT-adenosine (N-Fmoc) | 5'-DMT-adenosine (N-Fmoc) standing as an exceptional biomedical compound, extensively deployed to study select diseases fusing the advantageous attributes of 5'-DMT-adenosine and the safeguarding prowess of N-Fmoc. Grade: ≥ 98% by HPLC. Molecular formula: C46H41N5O8. Mole weight: 791.85. | |
| 5'-DMT-adenosine (N-PAC) | 5'-DMT-adenosine (N-PAC) is a remarkable biomedical compound, used to study intricate cardiovascular maladies like cardiac arrhythmias and coronary artery diseases. Its profound efficacy derives from its exquisite modulation of adenosine receptors. Grade: ≥ 98% by HPLC. Molecular formula: C39H37N5O8. Mole weight: 703.74. | |
| 5'-DMT-cytidine (N-Ac) | 5'-DMT-cytidine (N-Ac) is a nucleoside analog, widely used in the biomedical industry for treating various types of cancers and viral infections. It acts as an antiproliferative agent by inhibiting DNA synthesis and induces apoptosis in cancer cells. Furthermore, it also exhibits antiviral activity against several viruses like cytocidal activity against Hepatitis B and C virus. Grade: ≥ 98% by HPLC. Molecular formula: C32H33N3O8. Mole weight: 587.62. | |
| 5'-DMT-cytidine (N-Bz) | 5'-DMT-cytidine (N-Bz) is a prodigious inhibitor, unveiling its tremendous potential in studying cancer. It dexterously directs its assault towards specific enzymes intricately entwined in the delicate processes of DNA replication and repair. Grade: ≥ 98% by HPLC. Molecular formula: C37H35N3O8. Mole weight: 649.69. | |
| 5'-DMT-cytidine (N-Fmoc) | 5'-DMT-cytidine (N-Fmoc) is a prominent research chemical in the biomedicine industry. Its utilization is widespread, with its effectiveness being investigated in the activity of cytidine analogues subjected to N-terminus modification. Such research is imperative for the production of new drugs with greater potency intended for cancer and viral disease treatment. Grade: ≥ 98% by HPLC. Molecular formula: C45H41N5O9. Mole weight: 767.82. | |
| 5'-DMT-cytidine (N-iBu) | 5'-DMT-cytidine (N-iBu), an immensely potent antiviral nucleoside analog, conspicuously stands out in treating viral infections, for instance, the stubborn hepatitis B and C. Chemical biochemistry declares that it breaks in and incapacitates the viral DNA polymerase, curtailing the growth and spread of viruses within the body. Comprising of therapeutic powers beyond the virulent world, preliminary studies have also legitimized its probable role in the treatment of certain cancer genres. Grade: ≥ 98% by HPLC. Molecular formula: C34H37N3O8. Mole weight: 615.67. | |
| 5'-DMT-cytidine (N-PAC) | 5'-DMT-cytidine (N-PAC), a compelling prospective anti-cancer drug, operates via regulation of DNA methylation, a key contributor to the progression of malignant tumors. Encouraging outcomes have emerged, evidently indicating its potential effectiveness in treating lung cancer, leukemia, and other malignancies. Grade: ≥ 98% by HPLC. Molecular formula: C38H37N3O9. Mole weight: 679.72. | |
| 5'-DMT-guanosine (N-Fmoc) | 5'-DMT-guanosine (N-Fmoc). A derivative of nucleotides, this compound has far-reaching applications in biomedical research - chiefly, but not exclusively, in the creation of oligonucleotides. Fantastic potential is expected for new developments in treatments for cancer, viral infections, and other such diseases, with this compound acting as a key starting material. Grade: ≥ 98% by HPLC. Molecular formula: C46H41N5O9. Mole weight: 807.85. | |
| 5'-DMT-guanosine (N-iBu) | 5'-DMT-guanosine (N-iBu) is an indispensable compound specifically aiming in studying neurological ailments such as Alzheimer's disease and Parkinson's disease. Grade: ≥ 98% by HPLC. Molecular formula: C35H37N5O8. Mole weight: 655.7. | |
| 5'-DMT-guanosine (N-PAC) | N-PAC, also known as 5'-DMT-guanosine, is an intriguing nucleotide analogue that holds promise in chemical biology research. Among its many properties, it stands out as a selective inhibitor of Francisella tularensis, the causative agent of tularemia. But that's just the tip of the iceberg- N-PAC may also have exciting implications for chemotherapy treatment of triple-negative breast cancer. With its multifaceted potential, N-PAC is a compound that is sure to pique the interest of researchers and clinicians alike. Grade: ≥ 98% by HPLC. Molecular formula: C39H37N5O9. Mole weight: 719.74. | |
| 5'-DMT-N1-Methyl-PseudoUridine | 5'-DMT-N1-Methyl-PseudoUridine is a pivotal compound in studying viral infections and gene therapeutic interventions. This compound orchestrates an inhibitory effect on viral replication. Distinguished by its unparalleled chemical configuration, it impeccably accommodates RNA modifications. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-N1-methylpseudoUridine; 5'-O-DMT-N1-methylpseudouridine; 5'-O-(4,4'-dimethoxitrityl)-1-N-methylpseudouridine; 5-[(2S,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-1-methylpyrimidine-2,4-dione. Grade: ≥95%. CAS No. 875302-39-9. Molecular formula: C31H32N2O8. Mole weight: 560.59. | |
| 5'-DMT-N3-methyl-2'-deoxythymidine | 5'-DMT-N3-methyl-2'-deoxythymidine is a vital compound playing a crucial role in studying and developing diagnostic tools and antiviral therapies for diseases like HIV/AIDS. It can be used to study viral replication and design potent antiretroviral drugs making it an indispensable tool in the fight against viral infections. Grade: ≥ 98% by HPLC. Molecular formula: C32H34N2O7. Mole weight: 558.62. | |
| 5'-DMT-NHS-Carboxy dU 3'-Phosphoramidite | 5'-DMT-NHS-Carboxy dU 3'-Phosphoramidite is a phosphoramidite compound used in the synthesis of oligonucleotides. It is designed to incorporate a modified deoxyuridine nucleotide into DNA strands, which can enhance the stability and functionality of the synthesized oligonucleotides. This compound is used to improve the metabolic stability and binding affinity of the synthesized oligonucleotides, making them more suitable for specific biological applications such as gene regulation, and antisense therapy. Synonyms: N-Hydroxysuccinimide carboxy-dT phosphoramidite; 2-Propenoic acid, 3-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 3-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-2-propenoate; NHS-Carboxy-dT; 5'-Dimethoxytrityl-5-[3-acrylate NHS ester]-2'-deoxyUridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-DMT-5-NHS-carboxy-2'-deoxy-rU 3'-Phosphoramidite. CAS No. 1354695-41-2. Molecular formula: C46H52N5O12P. Mole weight: 897.91. | |
| 5'-DMT-PseudoUridine | 5'-DMT-PseudoUridine, a pivotal compound within the field of biomedicine, plays a profound and indispensable part in the therapeutic approach towards various diseases, enabling the alteration of RNA molecules. Its unparalleled characteristics not only bolster RNA stability but also foster heightened protein synthesis and regulate cellular mechanisms. Synonyms: SCHEMBL1750218; 144429-55-0; 5-((2S,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. CAS No. 144429-55-0. Molecular formula: C30H30N2O8. Mole weight: 546.57. | |
| 5'-DMT-uridine | 5'-DMT-uridine is a remarkable compound, exhibiting its efficacy in the research of neurodegenerative disorders, such as Alzheimer's and Parkinson's disease. It has unparalleled ability to induce neuroregeneration and shield neurons from oxidative stress. Grade: ≥ 98% by HPLC. Molecular formula: C30H30N2O8. Mole weight: 546.57. | |
| 5'-dUMPS | 5'-dUMPS is a potent, competitive inhibitor that regulates enzymes. It can interact with 2'-deoxypyrimidine-5'- monophosphate. Synonyms: 2'- Deoxyuridine- 5'- O- monophosphorothioate, sodium salt. Grade: ≥ 97 % by HPLC. CAS No. 205379-91-5. Molecular formula: C9H13N2O7PS (free acid). Mole weight: 324.3 (free acid). | |
| 5-epi Emtricitabine Carboxylic Acid | 5-epi Emtricitabine Carboxylic Acid is an impurity of 5-epi Emtricitabine; an epimer of Emtricitabine which is a nucleoside reverse transcriptase inhibitor approved for treatment of HIV-1. Emtricitabine also has antagonistic activity against the hepatitis B virus. Synonyms: (2R,5R)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid. Molecular formula: C8H8FN2O4S. Mole weight: 261.23. | |
| 5-epi-Isofagomine | 5-epi-isofagomine, a highly potent and selective inhibitor, has garnered substantial attention in the biomedical realm due to its remarkable efficacy against Gaucher disease. This scientific marvel operates by skillfully impeding the glucocerebrosidase enzyme, ensuring an impediment in the accumulation of glucocerebroside within cells. Synonyms: 5-epi-(3R,4R,5R)-5-(hydroxymethyl)-3,4-piperidinediol; (3R,4R,5S)-5-(Hydroxymethyl)-3,4-piperidinediol; 3,4-Piperidinediol, 5-(hydroxymethyl)-, [3R-(3α,4β,5β)]-; 3,4-Piperidinediol, 5-(hydroxymethyl)-, (3R,4R,5S)-. CAS No. 202979-51-9. Molecular formula: C6H13NO3. Mole weight: 147.17. | |
| 5-epi-Jinkoheremol | 5-epi-Jinkoheremol shows the stronger fungicidal activity than validamycin. Synonyms: 2-Naphthalenemethanol, 1,2,3,5,6,7,8,8a-octahydro-α,α,8,8a-tetramethyl-, (2R,8R,8aR)-. CAS No. 2567930-96-3. Molecular formula: C15H26O. Mole weight: 222.37. | |
| 5-Ethoxymethyluridine | 5-Ethoxymethyluridine, a remarkable biomedicine, stands as an invaluable asset for combatting an extensive array of diseases. Functioning as a nucleoside analog, it significantly hinders viral replication, rendering it indispensable in the battle against RNA viruses. Synonyms: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(ethoxymethyl)pyrimidine-2,4-dione. Grade: ≥95%. CAS No. 95468-92-1. Molecular formula: C12H18N2O7. Mole weight: 302.28. | |
| 5-Ethyl-10-methoxy dibenzazepine | An impurity of Oxcarbazepine which is an anticonvulsant and mood stabilizing therapeutic for neuropathic pain, epilepsy, and affective disorders. Synonyms: 5-Ethyl-10-methoxy dibenzazepine; 5-Ethyl-10-methoxy iminostilbene; 11-ethyl-5-methoxybenzo[b][1]benzazepine; 5-Ethyl-10-methoxy-5H-dibenzo(b,f)azepine; 5H-Dibenz(b,f)azepine, 5-ethyl-10-methoxy-; 5-Ethyl-10-methoxy-5H-dibenz[b,f]azepine; 5-Ethyl-10-methoxy-5H-dibenzo[b,f]azepine. Grade: > 95%. CAS No. 15882-79-8. Molecular formula: C17H17NO. Mole weight: 251.33. | |
| 5-Ethyl-1,3-dihydro-1-(2,3,5,6-tetrafluorophenyl)-2H-indol-2-one | 5-Ethyl-1,3-dihydro-1-(2,3,5,6-tetrafluorophenyl)-2H-indol-2-one is an impurity of Robenacoxib, a nonsteroidal anti-inflammatory drug (NSAID) used for the relief of pain and inflammation in cats and dogs. Synonyms: N-(2,3,5,6-tetrafluorophenyl)-5-ethyloxindole; 5-Ethyl-1-(2,3,5,6-tetrafluorophenyl)indolin-2-one. CAS No. 220991-61-7. Molecular formula: C16H11F4NO. Mole weight: 309.26. | |
| 5-Ethyl-2'-deoxyuridine-d5 | Isotope labelled 5-Ethyl-2'-deoxyuridine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil, a potent antineoplastic agent in clinical use. Synonyms: 2'-Deoxy-5-ethyluridine-d5; 5-Ethyl-1-(2'-deoxy-β-D-ribofuranosyl)uracil-d5; 5-Ethyl-2'-deoxyuridine-d5; 5-Ethyldeoxyuridine-d5; Aedurid-d5; EDU-d5; EUDR-d5; Edoxudine-d5; Epoxudine-d5; ORF 15817-d5; RWJ 15817-d5; β-5-Ethyl-2'-deoxyuridine-d5; β-5-Ethyldeoxyuridine-d5. Molecular formula: C11H11D5N2O5. Mole weight: 261.29. | |
| 5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine | 5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine is a remarkable antiviral compound, used in research of herpes simplex virus (HSV) infections. By functioning as a nucleoside analog and effectively hampering viral DNA enhancement, it efficaciously obstructs viral replication. The distinctive structure of this compound renders it exceptionally promising for extensive biomedical exploration and drug development directed towards HSV-associated afflictions. Synonyms: Uridine, 2'-deoxy-5-ethyl-, 3',5'-bis(p-chlorobenzoate). Grade: 98%. CAS No. 25137-84-2. Molecular formula: C25H22Cl2N2O7. Mole weight: 533.36. | |
| 5-ethyl 3-isopropyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate | An impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. CAS No. 2170716-02-4. Molecular formula: C22H29ClN2O5. Mole weight: 436.93. | |
| 5-Ethyl-4-thiouridine | 5-Ethyl-4-thiouridine is a paramount biomedical compound, intricately contributing to nucleotide research. Profoundly utilized as a chemical probe in RNA modification studies, this compound augments inquiries into the ramifications of thiouridine on RNA's structure and functionality. Manifesting its significance in relation to ailments encompassing cancer, RNA-related disorders and viral infections, it fosters comprehension of its disease-associated role. Synonyms: Uridine, 5-ethyl-4-thio-; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one. Grade: ≥95%. CAS No. 148744-32-5. Molecular formula: C11H16N2O5S. Mole weight: 288.32. | |
| 5'-Ethylcarboxamido-2',3'-isopropylidene Adenosine | A useful template for the development of A2B adenosine receptor agonists. It was confirmed to be a full agonist in a functional assay based on the measurement of its capacity to modulate cAMP levels in CHO cells expressing the hA2B receptor. Synonyms: 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide; 2',3'-O-isopropylidene-NECA. CAS No. 39491-53-7. Molecular formula: C15H20N6O4. Mole weight: 348.36. | |
| 5'-Ethylcarboxamido-adenosine | 5'-Ethylcarboxamido-adenosine, a remarkable biomedicine, exhibits its prowess in cancer therapeutics. This extraordinary compound operates as an adenosine receptor agonist, effectively restraining the proliferation of malignant cells while orchestrating apoptosis. Uses: Vasodilator agents. Synonyms: NECA; 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-b-D-ribofuranuronamide; 5'-Ethylcarboxamido-D-adenosine. Grade: ≥ 95% by HPLC. CAS No. 35920-39-9. Molecular formula: C12H16N6O4. Mole weight: 308.29. | |
| 5-Ethylcarboxy-dC(Bz) Phosphoramidite | 5-Ethylcarboxy-dC(Bz) Phosphoramidite is a modified phosphoramidite where the cytosine base is functionalized with an ethylcarboxy group at the 5-position and protected with a benzoyl (Bz) group on the exocyclic amine. The sugar moiety is designed with a 3'-phosphoramidite functionality for compatibility with automated DNA synthesis. This compound is commonly used to introduce chemically modified cytosine residues into oligonucleotides, enabling studies on DNA-protein interactions, epigenetic modifications, and the effects of base alterations on nucleic acid stability and function. It is particularly useful in therapeutic oligonucleotide development and molecular biology research. Synonyms: 5-Pyrimidinecarboxylic acid, 4-(benzoylamino)-1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-, ethyl ester; 5-Carboxy-dC-CE Phosphoramidite; 5'-Dimethoxytrityl-N-benzoyl-5-ethylcarboxy-2'-deoxycytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; DNA 5-carbethoxy-C(Bz) amidite. Grade: ≥95%. CAS No. 1535202-71-1. Molecular formula: C49H56N5O10P. Mole weight: 905.97. | |
| 5-Ethylcytidine | 5-Ethylcytidine is a vital compound extensively used in the biomedical industry for developing antiviral and antitumor drugs. Synonyms: 5-ethyl-cytidine; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethylpyrimidin-2(1H)-one. Grade: ≥95%. CAS No. 56367-98-7. Molecular formula: C11H17N3O5. Mole weight: 271.27. | |
| 5-Ethyl-demethyl Lercanidipine | 5-Ethyl-demethyl Lercanidipine is an impurity of Lercanidipine, which is a dihydropyridine calcium channel blocker. Synonyms: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid; 3-[2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-ethyl Ester; 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid; 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Ethyl Ester; Lercandipine Impurity II. Grade: 98%. CAS No. 786625-22-7. Molecular formula: C37H43N3O6. Mole weight: 625.75. | |
| 5-Ethyluridine | 5-Ethyluridine, a remarkable biomedicine, occupies a pivotal position in the scientific realm, facilitating extensive exploration of pharmacological realms. Notably, this compound finds widespread employment in the synthesis and formulation of antiviral agents, with a particular focus on countering the perilous human immunodeficiency virus (HIV). Synonyms: Uridine, 5-ethyl-; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethylpyrimidine-2,4(1H,3H)-dione. Grade: ≥95%. CAS No. 25110-76-3. Molecular formula: C11H16N2O6. Mole weight: 272.25. | |
| 5-Ethynyl-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-β-D-ribofuranosyl)imidazo-4-carbonitrile | 5-Ethynyl-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-β-D-ribofuranosyl)imidazo-4-carbonitrile is a compound useful in organic synthesis. Synonyms: 5-Ethynyl-1-[2,3,5-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-1H-imidazole-4-carbonitrile. CAS No. 147212-83-7. Molecular formula: C29H53N3O4Si3. Mole weight: 592.01. | |
| 5-Ethynyl-1-(β-D-ribofuranosyl)-imidazo-4-carbonitrile | 5-Ethynyl-1-(β-D-ribofuranosyl)-imidazo-4-carbonitrile is a compound useful in organic synthesis. Synonyms: 1-[(2R,3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-5-ETHYNYLIMIDAZOLE-4-CARBONITRILE; 1H-Imidazole-4-carbonitrile, 5-ethynyl-1-beta-D-ribofuranosyl-; 5-Ethynyl-1-(beta-D-ribofuranosyl)-imidazo-4-carbonitrile; SCHEMBL9697576; CHEMBL4463936; OAMMFSMFVAEFOI-GWOFURMSSA-N; 5-ETHYNYL-1-(B-D-RIBOFURANOSYL)-IMIDAZO-4-CARBONITRILE; 5-Ethynyl-1-(?-D-ribofuranosyl)-imidazo-4-carbonitrile; 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carbonitrile. CAS No. 126004-13-5. Molecular formula: C11H11N3O4. Mole weight: 249.22. | |
| 5'-Ethynyl-2'-deoxycytidine | 5'-Ethynyl-2'-deoxycytidine (EdC) is a nucleoside analog that inhibits replication of the herpes simplex virus-1 (HSV-1) KOS strain (ID50 = 0.2 μg/mL). It also reduces virus-induced cytopathogenicity of HSV-1, HSV-2, and vaccinia virus strains in PRK cells (MICs = 0.2-0.4, 1-2, and 5 μg/ml, respectively). Synonyms: EdC; 2'-deoxy-5-Ethynylcytidine; 5-Ethynyl-2-deoxycytidine. Grade: ≥98%. CAS No. 69075-47-4. Molecular formula: C11H13N3O4. Mole weight: 251.2. | |
| 5-Ethynyl-2'-deoxy-cytidine (5-EdC) | 5-Ethynyl-2'-deoxy-cytidine (5-EdC) is an ethynyl-labeled deoxycytidine. It is incorporates into replicating DNA to measures de novo DNA synthesis during S-phase. Synonyms: 5-Ethynyl-2'-deoxycytidine. Grade: ≥ 99% by HPLC. Molecular formula: C11H13N3O4. Mole weight: 251.24. | |
| 5-Ethynylcytidine | 5-Ethynylcytidine is an eminent biomedical compound, employed as a nucleoside analog. It vigorously impedes viral replication and ushers in the righteous realm of apoptosis within malignant cells. Indeed, its profound efficacy can be attributed to its tenacious interference with nucleic acid research and development and relentless disruption of protein functionality. Synonyms: 5-ethynyl-cytidine. Grade: ≥ 97% (HPLC). CAS No. 65223-78-1. Molecular formula: C11H13N3O5. Mole weight: 267.24. | |
| 5-Ethynyl Nicotine | 5-Ethynyl Nicotine is a potent synthetic compound, serving as a valuable tool for exploring the intricate ramifications of nicotine on the highly intricate central nervous system. It is renowned for its extensive utilization in delving into the perplexing research of nicotine addiction. Uses: An intermediate of nicotinic acetylcholine receptor agonist sib-1508y. used for the treatment of neurological disorders. Synonyms: 3-Ethynyl-5-[(2S)-1-methyl-2-pyrrolidinyl]pyridine; (S)-3-Ethynyl-5-(1-methyl-2-pyrrolidinyl)pyridine; Altinicline; SIB 1508. Grade: 96%. CAS No. 179120-92-4. Molecular formula: C12H14N2. Mole weight: 186.25. | |
| 5-Ethynylpyrimidine | 5-Ethynylpyrimidine, an indispensable compound within the biomedical sector, assumes a pivotal function in the synthesis of pharmaceuticals and innovative drug candidates targeting a myriad of diseases. Its exceptional attributes facilitate profound investigations crucial for advancing therapeutic interventions across diverse medical domains including cancer, viral infections, and neurological disorders. Synonyms: Pyrimidine, 5-ethynyl-(9CI). Grade: 95%. CAS No. 153286-94-3. Molecular formula: C6H4N2. Mole weight: 104.11. | |
| 5-Ethynyl-UTP | 5-Ethynyl-UTP is a compound acting as a ubiquitous substrate to foster DNA research and development and modification. Synonyms: 5-Ethynyluridine 5'-(tetrahydrogen triphosphate); 5-Ethynyl-deoxyuridine triphosphate; 5-Ethynyl uridine-triphosphate. Grade: ≥95% by HPLC. CAS No. 1004955-96-7. Molecular formula: C11H15N2O15P3. Mole weight: 508.16. | |
| 5'-Ferrocene CE Phosphoramidite | 5'-Ferrocene CE Phosphoramidite is an oligonucleotide synthesis reagent that adds the electromagnetic group ferrocene to the oligonucleotide chain for application in oligonucleotide labeling. The absorption wavelength of 5'-Ferrocene CE Phosphoramidite is 438 nm and the extinction coefficient is 230M-1 cm-1. Synonyms: 5'-Ferrocene Amidite; N-Ferrocenoyl-6-aminohexan-1-(2-cyanoethyl-diisoproylamino phoshoramidite). Molecular formula: C26H40FeN3O3P. Mole weight: 529.44. | |
| 5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-5'-O-acetyl-b-L-ribofuranosyl)-uracil | 5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-5'-O-acetyl-b-L-ribofuranosyl)-uracil is a highly efficacious synthetic nucleoside analog utilized in the research of human immunodeficiency virus (HIV) infection. Its mechanism of action involves robust inhibition of HIV reverse transcriptase, impeding viral replication and significantly ameliorating viral burden. Synonyms: 5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-5'-O-acetyl-β-L-ribofuranosyl)-uracil; [(2R,5S)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methyl acetate. CAS No. 1421336-32-4. Molecular formula: C11H11FN2O5. Mole weight: 270.22. | |
| 5-Fluoro-1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-b-L-arabinofuranosyl)-uracil | 5-Fluoro-1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-b-L-arabinofuranosyl)-uracil is also known as F-deoxy-F-BzAraU, utilized in the research of specific DNA viruses including herpes simplex and varicella-zoster. Through hinderance of viral DNA replication, it effectively curbs the dissemination and development of viral infections. Synonyms: 1-(3,5-Di-O-benzoyl-2-deoxy-2-fluoro-beta-L-arabinofuranosyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione; 2,4(1H,3H)-Pyrimidinedione, 1-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-L-arabinofuranosyl)-5-fluoro-. CAS No. 178687-87-1. Molecular formula: C23H18F2N2O7. Mole weight: 472.40. | |
| 5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil | 5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil is a robust compound, used in research of diverse viral infections, breast, lung and gastrointestinal tumors. Embodying exceptional inhibitory activity, this compound serves as an invaluable asset for the research and development of both antiviral and antitumor. Synonyms: 5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-β-L-lyxofuranosyl)-uracil. Grade: ≥95%. Molecular formula: C28H24F2N2O5. Mole weight: 506.51. | |
| 5-Fluoro-1-(β-D-ribopyranosyl)-2,4(1H,3H)-pyrimidinedione | 5-Fluoro-1-(β-D-ribopyranosyl)-2,4(1H,3H)-pyrimidinedione is a remarkable compound, showcasing its antiviral properties. This concoction exerts a inhibitory efficacy against certain RNA virus strains. Its modus operandi lies in its adeptness at impeding viral replication through disruption of the intricate enhancement of viral genetic material. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-β-D-ribopyranosyl-; 5-fluoro-1-((2R,3R,4R,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grade: ≥95%. CAS No. 77180-80-4. Molecular formula: C9H11FN2O6. Mole weight: 262.19. | |
| 5-Fluoro-1-(b-L-ribofuranosyl)-uracil | 5-Fluoro-1-(b-L-ribofuranosyl)-uracil is a powerful antineoplastic compound, exhibiting immense potential in research of diverse malignancies. Renowned for its impact on inhibiting DNA enhancement and impeding cell proliferation, this remarkable compound emerges as an invaluable asset in the research and development of oncology. Synonyms: 1-beta-L-Ribofuranosyl-5-fluorouracil; L-5-Fluorouridine; 1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-fluoro-pyrimidine-2,4-dione; 5-Fluoro-1-(β-L-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione; L-β-Ribofuranosyl-5'-fluorouracil. Grade: 95%. CAS No. 77210-26-5. Molecular formula: C9H11FN2O6. Mole weight: 262.19. | |
| 5-fluoro 203 | The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. 5-fluoro 203 is a cytotoxic compound that at 1 μM activates AhR signaling. Synonyms: NSC 703786; 4-(5-fluoro-1,3-benzothiazol-2-yl)-2-methylaniline. Grade: ≥98%. CAS No. 260443-89-8. Molecular formula: C14H11FN2S. Mole weight: 258.3. | |
| 5-Fluoro-2'-deoxyuridine 5'-Monophosphate Ammonium Salt (up to 20% 3'-monophosphate) | 5-Fluoro-2'-deoxyuridine 5'-Monophosphate is used in the preparation of diaminomitosene nucleotide derivatives with anti-neoplastic activity. Synonyms: 2'-Deoxy-5-fluoro-5'-uridylic Acid Ammonium Salt. Grade: 90%. Molecular formula: C9H12FN2O8P xNH3. Mole weight: 326.17. | |
| 5-Fluoro-2'-deoxyuridine-5'-triphosphate (triethylammonium salt form) | An impurity of UTP. UTP is a pyrimidine nucleoside triphosphate as a substrate in the biosynthesis of RNA. Synonyms: FdUTP (triethylammonium salt form). Grade: 95%. CAS No. 1621676-99-0. Molecular formula: C9H14N2O14P3F.C6H15N. Mole weight: 486.135 (free acid). | |
| 5-Fluoro-2-ethoxy-4(1H)pyrimidinone | Fluorouracil Impurity F is a derivative of 5-fluorouracil. Uses: Ethoxy-5-fluoro-4(3h)-pyrimidinone (fluorouracil ep impurity f) is a derivative of 5-fluorouracil (3c,15n2 labelled, f596002) which is a potent antineoplastic agent in clinical use. Synonyms: 2-ethoxy-5-fluoro-1H-pyrimidin-6-one. Grade: > 95 %. CAS No. 56177-80-1. Molecular formula: C6H7FN2O2. Mole weight: 158.13. | |
| 5-Fluoro-2-methoxypyridine-3-carboxaldehyde | 5-Fluoro-2-methoxypyridine-3-carboxaldehyde is an essential constituent in pharmaceutical synthesis is assumes paramount significance in the creation of medicinal agents that study an array of maladies including malignancies, inflammations and neural malfunctions. Synonyms: 3-Pyridinecarboxaldehyde, 5-fluoro-2-methoxy-; 5-Fluoro-2-methoxy-3-pyridinecarboxaldehyde; 5-Fluoro-2-methoxynicotinaldehyde. Grade: ≥95%. CAS No. 351410-62-3. Molecular formula: C7H6FNO2. Mole weight: 155.13. | |
| 5-Fluoro-2'-O-methyl-4-(methylithio)uridine | 5-Fluoro-2'-O-methyl-4-(methylithio)uridine is a potent compound, garnering significant attention owing to its exceptional efficacy in research of a myriad of viral infections. Its mechanism of action lies in proficiently inhibiting viral replication. Synonyms: 5-Fluoro-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-4-methylsulfanylpyrimidin-2-one; 5-FLUORO-2'-O-METHYL-4-(METHYLTHIO)PYRIMIDIN-2-ONE. Grade: 95%. CAS No. 869222-67-3. Molecular formula: C11H15FN2O5S. Mole weight: 306.22. | |
| 5-Fluoro-2'-O-methyl-4-thiouridine | 5-Fluoro-2'-O-methyl-4-thiouridine is an esteemed compound, unraveling itself through potent antiviral attributes. With astute acumen, this compound assiduously curbs viral replication, emerging as an invaluable asset in the research of influenza infection. Synonyms: 5-FLUORO-2'-O-METHYL-4-THIOURIDINE. Grade: 95%. CAS No. 869355-51-1. Molecular formula: C10H13FN2O5S. Mole weight: 292.29. | |
| 5-Fluoro-2'-O-methyluridine | 5-Fluoro-2'-O-methyluridine is a highly bioactive nucleoside compound, finding extensive utilization in the research and development of groundbreaking antiviral medications. Boasting remarkable potential, this compound showcases inhibitory efficacy against distinct RNA viruses. Synonyms: 5-Fluoro-2'-O-methyl-D-uridine; 5-Fluoro-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione. CAS No. 61671-80-5. Molecular formula: C10H13FN2O6. Mole weight: 276.22. | |
| 5-Fluoro-2-oxindole | 5-Fluoro-2-oxindole is an impurity of Sunitinib, which is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). Synonyms: 2H-Indol-2-one, 5-fluoro-1,3-dihydro-; 5-Fluoro-1,3-dihydro-2H-indol-2-one; 5-Fluoro-2,3-dihydro-2-oxoindole; 5-Fluoro-2,3-dihydroindol-2-one; 5-Fluoro-2-oxoindoline; 5-Fluoroindolin-2-one; 5-Fluorooxindole. Grade: ≥95%. CAS No. 56341-41-4. Molecular formula: C8H6FNO. Mole weight: 151.14. | |
| 5-Fluoro-3'-beta-C-methyluridine | 5-Fluoro-3'-beta-C-methyluridine is an immensely powerful antiviral entity, exhibiting inhibitory efficacy against select RNA viruses, notably hepatitis C virus and Zika virus. Focusing on its modus operandi, it exerts its effects by markedly impeding theenhancement and replication of viral RNA. Synonyms: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-4-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione; 5-Fluoro-3'-C-methyluridine. Grade: ≥95%. Molecular formula: C10H13FN2O6. Mole weight: 276.22. | |
| 5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)ethyl]-4(3H)-quinazolinone | 5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)ethyl]-4(3H)-quinazolinone is an impurity of Idelalisib, which is a kinase inhibitor used in combination with rituximab for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL). Synonyms: 4(3H)-Quinazolinone, 5-fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)ethyl]-; 4(3H)-Quinazolinone, 5-fluoro-3-phenyl-2-[(1S)-1-(1H-purin-6-ylamino)ethyl]-; (S)-2-(1-(9H-Purin-6-ylamino)ethyl)-5-fluoro-3-phenylquinazolin-4(3H)-one. Grade: 95%. CAS No. 870281-17-7. Molecular formula: C21H16FN7O. Mole weight: 401.40. | |
| 5-Fluoro-4'-C-methylcytidine | 5-Fluoro-4'-C-methylcytidine, an exceptional antiviral compound, exhibits remarkable potential in biomedical applications for targeting diverse viral infections. Its unparalleled efficacy extends to RNA viruses, such as hepatitis C virus (HCV) and the notorious SARS-CoV-2. This nucleotide analog disrupts viral RNA synthesis, effectively impeding viral replication. Captivating studies have unveiled its promising role as a therapeutic agent for combating viral diseases, thereby instigating renewed interest in intensified research and development of cutting-edge antiviral treatments. Proceeding into the realm of this scientific wonder, we embark upon a profound exploration. Synonyms: Cytidine, 5-fluoro-4'-C-methyl-; 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-5-methyloxolan-2-yl]-5-fluoropyrimidin-2-one; 4-Amino-1-[5-deoxy-4-(hydroxymethyl)-α-L-lyxofuranosyl]-5-fluoro-2(1H)-pyrimidinone. Grade: ≥95%. CAS No. 791585-24-5. Molecular formula: C10H14FN3O5. Mole weight: 275.23. | |
| 5-Fluoro-4'-C-methyluridine | 5-Fluoro-4'-C-methyluridine is a pivotal chemical compound widely employed in the biomedical sector, showcasing remarkable antiviral attributes. It is tailored for research of viral infections. Synonyms: Uridine, 5-fluoro-4'-C-methyl-; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-5-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione; 1-[5-Deoxy-4-(hydroxymethyl)-α-L-lyxofuranosyl]-5-fluoro-2,4(1H,3H)-pyrimidinedione. Grade: ≥95%. CAS No. 660845-69-2. Molecular formula: C10H13FN2O6. Mole weight: 276.22. | |
| 5-Fluoro-4'-thio-cytidine | 5-Fluoro-4'-thio-cytidine is a remarkably potent antiviral compound extensively employed in the biomedical sector, acting a cytidine-derived substance. This compound proves integrally indispensable for research of combatting viral maladies. Grade: ≥95%. Molecular formula: C9H12FN3O4S. Mole weight: 277.27. | |
| 5-Fluoro-4'-thiouridine | 5-Fluoro-4'-thiouridine is an influential pharmaceutical compound, used for studying diverse ailments, encompassing leukemia, pancreatic cancer and viral afflictions. Its inhibitory effects against both viruses and cancer cells are attributed to the inhibition of RNA enhancement and the initiation of apoptosis. Synonyms: Uridine, 5-fluoro-4'-thio-; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-5-fluoropyrimidine-2,4-dione. Grade: ≥95%. CAS No. 56527-42-5. Molecular formula: C9H11FN2O5S. Mole weight: 278.26. | |
| 5'-Fluoro-5'-deoxy-adenosine | 5'-Fluoro-5'-deoxy-adenosine is an impressive antiviral compound, exhibiting inhibitory efficacy in studying an array of viral afflictions including influenza, herpes and HIV. This compound, revered for its impeccable inhibitory capabilities restraining viral replication while thwarting viral dissemination, emerges as an auspicious contender for the development of avant-garde antiviral researchs. Synonyms: 5'-FDA; 5'-fluoro-5'-deoxyadenosine; 5'-deoxy-5'-fluoroadenosine. CAS No. 731-98-6. Molecular formula: C10H12FN5O3. Mole weight: 269.23. | |
| 5-Fluoro-6-iodouridine | 5-Fluoro-6-iodouridine is an exceptionally powerful compound with remarkable antiviral attributes due to its distinctive amalgamation of fluorine and iodine moieties. It operates by proficiently impeding viral replication while concurrently diminishing the viral burden. Synonyms: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoro-6-iodopyrimidine-2,4-dione. Grade: ≥ 95%. CAS No. 87818-06-2. Molecular formula: C9H10FIN2O6. Mole weight: 388.09. | |
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