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5-Hydroxymethylxylo-uridine
5-Hydroxymethylxylo-uridine is a potent biomedical compound widely utilized in the realm of neurology, exhibiting remarkable neuroprotective efficacy. Synonyms: 5-hydroxymethyl-1-β-D-xylofuranosyl-1H-pyrimidine-2,4-dione; 1-β-D-Xylofuranosyl-5-hydroxymethyl-uracil; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-hydroxymethyl-1H-pyrimidine-2,4-dione; 1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione; 5-(Hydroxymethyl)-1-(β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione. Grade: ≥95%. CAS No. 52448-09-6. Molecular formula: C10H14N2O7. Mole weight: 274.23.
5-Hydroxynepafenac-d5
5-Hydroxynepafenac-d5 is a labelled imourity of nepafenac. Nepafenac is a nonsteroidal anti-inflammatory drug (NSAID) ued to treat inflammations. Grade: 95% by HPLC; 98% atom D. Molecular formula: C15H9D5N2O3. Mole weight: 275.31.
5-hydroxy-Nω-methyl tryptamine oxalate
5-Hydroxy-Nω-methyl tryptamine is a metabolite of serotonin in humans that has also been found in plants. Synonyms: N-methyl-5-HT; N-methyl Serotonin; N-methyl-5-hydroxy Tryptamine; 3-(2-Methylaminoethyl)indol-5-ol oxalate. Grade: ≥95%. CAS No. 15558-50-6. Molecular formula: C11H14N2O·xC2H2O4. Mole weight: 280.3.
5-Hydroxy Omeprazole
5-Hydroxy Omeprazole is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: 5-Hydroxyomeprazole; 4-Methoxy-6-{[(5-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl}-5-methyl-3-pyridinemethanol; 5-Methoxy-2-{[(5-hydroxymethyl-4-methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole; Hydroxyomeprazole. Grade: >95%. CAS No. 92340-57-3. Molecular formula: C17H19N3O4S. Mole weight: 361.42.
5-Hydroxy Omeprazole-d3 Sulfone
A metabolite of Omeprazole, which is a proton pump inhibitor used in the treatment of dyspepsia. Synonyms: (4-methoxy-6-(((5-methoxy-1H-benzo[d]imidazol-2-yl)sulfonyl)methyl)-5-methylpyridin-3-yl)methanol-d3. Grade: > 95%. Molecular formula: C17H16D3NO5S. Mole weight: 380.44.
5-Hydroxyomeprazole sulphide
5-Hydroxyomeprazole sulphide is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: 4-Methoxy-6-[[(5-methoxy-1H-benzimidazol-2-yl)thio]methyl]-5-methyl-3-pyridinemethanol; (4-Methoxy-6-(((5-methoxy-1H-benzo[d]imidazol-2-yl)thio)methyl)-5-methylpyridin-3-yl)methanol. CAS No. 103876-99-9. Molecular formula: C17H19N3O3S. Mole weight: 345.42.
5'-Hydroxyphenyl carvedilol
A metabolite of Carvedilol. It is used in the treatment of hypertension. Synonyms: 3-[2-[[3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-4-methoxyphenol; 5-Hydroxycarvedilol; BM 140830. Grade: > 95%. CAS No. 142227-51-8. Molecular formula: C24H26N2O5. Mole weight: 422.49.
5'-Hydroxyphenyl Carvedilol Sulfate
5'-Hydroxyphenyl Carvedilol Sulfate is a metabolite of Carvedilol, which is a medication used to treat high blood pressure, congestive heart failure (CHF), and left ventricular dysfunction in otherwise stable people. Synonyms: 3-[2-[[3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-4-methoxyphenol 1-(Hydrogen Sulfate); Phenol, 3-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-4-methoxy-, 1-(hydrogen sulfate). Grade: ≥95%. CAS No. 142227-53-0. Molecular formula: C24H26N2O8S. Mole weight: 502.54.
5-Hydroxy Propafenone β-D-Glucuronide
A metabolite of Propafenone.Propafenone is an anti-arrhythmic medication.It can be used for the treatment of illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias. Synonyms: 1-[5-Hydroxy-2-[2-β-D-glucopyranuronosyl-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone; 1-[5-Hydroxy-2-[3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone Glucuronide. Grade: > 95%. Molecular formula: C27H35NO10. Mole weight: 533.58.
5-Hydroxy propafenone HCl
A metabolite of Propafenone.Propafenone is an anti-arrhythmic medication.It can be used for the treatment of illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias. Synonyms: 1-[5-Hydroxy-2-[2-hydroxy-3-(propylamino)propoxy]phenl]-3-phenyl-1-propanone Hydrochloride; GPV 129. Grade: > 95%. CAS No. 86384-10-3. Molecular formula: C21H27NO4.HCl. Mole weight: 393.91.
5-Hydroxy propafenone sulfate
A metabolite of Propafenone.Propafenone is an anti-arrhythmic medication.It can be used for the treatment of illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias. Synonyms: 1-[5-Hydroxy-2-[2-sulfo-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone; 1-[5-Hydroxy-2-[3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone Sulfate. Grade: > 95%. CAS No. 1346598-57-9. Molecular formula: C21H27NO7S. Mole weight: 437.52.
5-Hydroxy propranolol
5-Hydroxy propranolol is a metabolite of propranolol, a β-adrenergic receptor antagonist. Synonyms: 1-Naphthalenol, 5-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-. Grade: ≥98%. CAS No. 81907-82-6. Molecular formula: C16H21NO3. Mole weight: 275.3.
5-Hydroxypropranolol-b-D-glucuronide
5-Hydroxypropranolol-b-D-glucuronide is a vital pharmaceutical compound, a noteworthy metabolite derived from Propranolol. Known for its nonselective beta-adrenergic antagonist qualities, this compound showcases exceptional antiarrhythmic properties. Molecular formula: C22H29NO9. Mole weight: 451.47.
5'-Hydroxypropranolol-b-D-glucuronoside
5'-Hydroxypropranolol-b-D-glucuronoside is a remarkably efficacious pharmaceutical compound adeptly manifesting commendable beta-adrenergic blockade attributes, thereby displaying remarkable proficiencies in the research of cardiovascular maladies. Molecular formula: C22H29NO9. Mole weight: 451.47.
5-Hydroxy Propranolol Glucuronide (Mixture of Diastereomers)
A metabolite of Propranolol. Propranolol is a Beta 1 adrenergic receptor antagonist. It can be used for the treatment of high blood pressure, several types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors. Synonyms: 5-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-1-naphthalenyl β-D-glucopyranosiduronic acid. Grade: >95%. CAS No. 127182-49-4. Molecular formula: C22H29NO9. Mole weight: 451.48.
5-Hydroxy Propranolol HCl
A metabolite of Propranolol.Propranolol is Beta 1 adrenergic receptor antagonist. It can be used for the treatment of high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors. Synonyms: 5-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-1-naphthalenol; 5'-Hydroxypropranolol Hydrochloride; ORF 12592. Grade: > 95%. CAS No. 62117-35-5. Molecular formula: C16H21NO3. HCl. Mole weight: 311.71.
5-Hydroxy rosiglitazone
An impurity of Rosiglitazone.Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. Synonyms: 5-[[4-[2-[(5-Hydroxy-2-pyridinyl)methylamino]ethoxy]phenyl]methyl]-2,4-thiazolidinedione. Grade: > 95%. CAS No. 257883-22-0. Molecular formula: C18H19N3O4S. Mole weight: 373.43.
5-Hydroxy rosiglitazone-d4 sulphate potassium salt
A labelled impurity of Rosiglitazone. Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. Grade: > 95%. Molecular formula: C18H14N3O7S2D4·K. Mole weight: 495.61.
5-Hydroxy rosiglitazone sulphate potassium salt
An impurity of Rosiglitazone.Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. Grade: > 95%. Molecular formula: C18H18N3O7S2.K. Mole weight: 491.59.
5-Hydroxy Saxagliptin
An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Uses: Dipeptidyl-peptidase iv inhibitors. Synonyms: 5-Hydroxy saxagliptin; 841302-24-7; Saxagliptin metabolite M2; PB91NV4HAN; Hydroxy Saxagliptin; UNII-PB91NV4HAN; BMS 510849; (1S,3S,5S)-2-((2S)-2-Amino-2-(3,5-dihydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)-2-azabicyclo(3.1.0)hexane-3-carbonitrile; 2-Azabicyclo(3.1.0)hexane-3-carbonitrile, 2-((2S)-2-amino-2-(3,5-dihydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)-, (1S,3S,5S)-; (1S,3S,5S)-2-[(2S)-2-Amino-2-(3,5-dihydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile; CHEMBL3350936; SCHEMBL13096265; BDBM11543; CHEBI:186991; PD045384; (S)-3,5-Dihydroxyadamantylglycine-L-cis-4,5-methanoprolinenitrile TFA salt; (1S,3S,5S)-2-((S)-2-amino-2-((1r,3R,5S,7S)-3,5-dihydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile; (1S,3S,5S)-2-[(2S)-2-amino-2-(3,5-dihydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile; 2,2,2-trifluoroacetic acid. Grade: > 95%. CAS No. 841302-24-7. Molecular formula: C18H25N3O3. Mole weight: 331.42.
5-Hydroxy Saxagliptin-13C3
An impurity of saxagliptin. Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Synonyms: (1S,3S,5S)-2-[(2S)-2-amino-2-(3,5-dihydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-Azabicyclo[3.1.0]hexane-3-carbonitrile-13C3. Grade: > 95%. Molecular formula: C1513C3H25N3O3. Mole weight: 334.39.
5-Hydroxy saxagliptin hydrochloride
5-Hydroxy saxagliptin is a major active metabolite of saxagliptin. Grade: ≥95%. Molecular formula: C18H25N3O3·HCl. Mole weight: 367.87.
5-Hydroxythalidomide
A metabolite of Thalidomide which was prescribed as an anti-nausea agent to help pregnant women with morning sickness but withdrawn from the market when it was discovered to cause birth defects. Synonyms: Thalidomide-5-OH; alpha-N-(4-Hydroxyphthalimido)-glutarimide. CAS No. 64567-60-8. Molecular formula: C13H10N2O5. Mole weight: 274.23.
5-Hydroxytoluene-2,4-disulphonic acid diammonium
5-Hydroxytoluene-2,4-disulphonic acid diammonium is an impurity of Policresulen, a topical hemostatic and antiseptic agent. Synonyms: 4-Hydroxy-6-methyl-1,3-benzenedisulfonic acid diammoniate; 1,3-Benzenedisulfonic acid, 4-hydroxy-6-methyl-, diammonium salt. Grade: ≥95%. Molecular formula: C7H14N2O7S2. Mole weight: 302.33.
5-Hydroxyuridine
5-Hydroxyuridine is an anticancer agent. 5-Hydroxyuridine is a modified nucleoside derived from uridine, commonly found in RNA molecules, especially in transfer RNA (tRNA), where it plays a significant role in RNA structure and function. Synonyms: Uridine, 5-hydroxy-; 1-(beta-D-ribofuranosyl)-5-hydroxypyrimidine-2,4(1H,3H)-dione; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-hydroxy-pyrimidine-2,4-dione; 1-β-D-Ribofuranosylisobarbituric acid; Isobarbituridine. Grade: ≥95%. CAS No. 957-77-7. Molecular formula: C9H12N2O7. Mole weight: 260.20.
5-Hydroxy-UTP
5-Hydroxy-UTP is an indispensable nucleotide analog, emerging as an alluring vanguard for unveiling the intricate foundations of RNA editing processes. Its resplendent implications extend their tendrils towards an incomparable studying of afflictions such as cancer and neurological disorders. Synonyms: 5-Hydroxyuridine-5'-Triphosphate; 5-hoUTP. Grade: ≥ 95% by HPLC. Molecular formula: C9H15N2O16P3 (free acid). Mole weight: 499.96 (free acid).
5-Hydroxyvitamin D3 25-glucuronide
5-Hydroxyvitamin D3 25-glucuronide is an esteemed and formidable biomolecule harnessed within the biomedical arena, used to study ailments stemming from vitamin D inadequacy, including osteoporosis, rickets and osteomalacia. Emanating from the glucuronidation process of 5-Hydroxyvitamin D3, this compound assumes a paramount role in governing the intricate balance of calcium and phosphate metabolism, fostering unyielding fortitude in skeletal architecture and augmenting the holistic fortification of the immune system. CAS No. 84344-78-5. Molecular formula: C33H52O8. Mole weight: 576.76.
5-I-dC-CE Phosphoramidite
5-I-dC-CE Phosphoramidite, an essential reagent in the synthesis of modified oligonucleotides, serves as a precursor for 5-iodo-2'-deoxycytidine-containing oligos, exhibiting impressive therapeutic efficacy against viral infections and cancer. Its incorporation into oligonucleotides results in improved stability and enzyme recognition, priming itself as a potent candidate for targeted molecular therapeutics. Synonyms: 5'-Dimethoxytrityl-N-benzoyl-5-iodo-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 178925-44-5. Molecular formula: C46H51IN5O8P. Mole weight: 959.83.
5-Iminodaunorubicin
5-Iminodaunorubicin, a quinone-modified anthracycline with antitumor activity, produces protein-concealed DNA strand breaks in cancer cells. Synonyms: NSC-833900; 5(8H)-Naphthacenone, 8-acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,9,10,12-tetrahydro-6,8,11-trihydroxy-12-imino-1-methoxy-, (8S-cis)-; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-11-imino-10-methoxy-6-oxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside. Grade: ≥95%. CAS No. 72983-78-9. Molecular formula: C27H30N2O9. Mole weight: 526.54.
5-Iminodaunorubicin hydrochloride
5-Iminodaunorubicin hydrochloride, a quinone-modified anthracycline with antitumor activity, produces protein-concealed DNA strand breaks in cancer cells. Synonyms: 5(8H)-Naphthacenone, 8-acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,9,10,12-tetrahydro-6,8,11-trihydroxy-12-imino-1-methoxy-, monohydrochloride, (8S-cis)-; NSC 254681; 8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,9,10,12-tetrahydro-6,8,11-trihydroxy-12-imino-1-methoxy-5(8H)-naphthacenone hydrochloride; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-11-imino-10-methoxy-6-oxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride (1:1). Grade: ≥95%. CAS No. 67324-99-6. Molecular formula: C27H31ClN2O9. Mole weight: 563.00.
5-Indole-aa-2'-deoxyuridine
5-Indole-aa-2'-deoxyuridine, known for its prominent role in the biomedical sector, is an exceptional antiviral marvel. Its unparalleled efficacy against the DNA polymerase of herpes simplex virus type 1 (HSV-1) propels it to the forefront of HSV-1 infection treatment. Synonyms: 5-Indole-aa-dU. Grade: ≥97% by HPLC. Molecular formula: C23H26N4O6. Mole weight: 454.48.
5'-Inosinic Acid Disodium Salt Hydrate
5'-Inosinic Acid Disodium Salt Hydrate, a quintessential biochemical reagent employed in the pharmaceutical industry, has been deployed to cure a myriad of afflictions such as gout, arthritis and hyperuricemia while simultaneously doubling up as a flavor enhancer in the world of food and beverage. Synonyms: 5'-Inosinic acid, sodium salt, hydrate (1:2:x); 5'-Inosinic acid, disodium salt, hydrate; Sodium 5'-inosinate hydrate (2:1:x); Inosinic-5'-disodium phosphate hydrate; Disodium 5'-inosinate hydrate. Grade: 97%. CAS No. 352195-40-5. Molecular formula: C10H11N4Na2O8P.xH2O. Mole weight: 392.17 (anhydrous basis).
5'-Inosinic acid, homopolymer, potassium salt
5'-Inosinic acid, homopolymer, potassium salt is a remarkable pharmaceutical compound, used for studying immune deficiencies and formidable viral infections. Synonyms: 5'-Inosinic acid, polymers, potassium salt; PolyI potassium salt; Potassium poly(I). CAS No. 26936-41-4. Molecular formula: (C10H13N4O8P)x.xK.
5-Iodo-1-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-imidazo-4-carbonitrile is a compound useful in organic synthesis. Synonyms: [(2R,3R,4R,5R)-3,4-Diacetyloxy-5-(4-cyano-5-iodoimidazol-1-yl)oxolan-2-yl]methyl acetate; 5-Iodo-1-(2',3',5'-tri-O-acetyl-beta-D-ribofuranosyl)-imidazo-4-carbonitrile; 5-IODO-1-(2',3',5'-TRI-O-ACETYL-B-D-RIBOFURANOSYL)-IMIDAZO-4-CARBONITRILE; 5-Iodo-1-(2',3',5'-tri-O-acetyl- beta -D-ribofuranosyl)-imidazo-4-carbonitrile; 5-Iodo-1-(2',3',5'-tri-O-acetyl-?-D-ribofuranosyl)-imidazo-4-carbonitrile; 5-Iodo-1-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-1H-imidazole-4-carbonitrile; 5-Iodo-1-(2 inverted exclamation mark ,3 inverted exclamation mark ,5 inverted exclamation mark -tri-O-acetyl-|A-D-ribofuranosyl)-imidazo-4-carbonitrile. CAS No. 59354-00-6. Molecular formula: C15H16IN3O7. Mole weight: 477.21.
5'-Iodo-2',3'-dideoxycytidine
It can be used as an antibiotic, and it is particularly effective against mycobacteria. Synonyms: 2',3'-dideoxy-5-iodocytidine; 5'-Iddc; 4-Amino-1-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one; IddC; 5-Iodo-2',3'-Dideoxy-D-Cytidine. Grade: ≥95%. CAS No. 114748-57-1. Molecular formula: C9H12IN3O3. Mole weight: 337.11.
5'-Iodo-2',3'-dideoxyuridine
5'-Iodo-2',3'-dideoxyuridine, known for its potent antiviral properties, is a remarkable therapeutic agent utilized in combating herpes simplex virus (HSV) infections. Through its ability to selectively impede viral DNA synthesis, it effectively hampers the replication of HSV, consequently providing relief from symptoms and shortening the duration of outbreaks. Molecular formula: C9H11N2O4I. Mole weight: 338.10.
5-Iodo-2'-C-methylcytidine
5-Iodo-2'-C-methylcytidine, an indispensable compound within biomedicine, encompasses formidable antiviral and antineoplastic attributes. Renowned for its unique nucleoside analogue nature, this compound finds extensive employment in pharmaceutical advancements targeting RNA viruses such as coronaviruses, flaviviruses, and retroviruses. Its unparalleled configuration and intricately orchestrated mechanism of action render it a propitious contender in the battle against diverse viral infections and specific malignancies. Synonyms: 5-Iodo-2'-C-methyl-1-β-D-ribofuranosylcytosine; 5-Iodo-2'-C-methyl Cytidine; 5-Iodo-2'-β-C-methyl cytidine; 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-5-iodopyrimidin-2-one. Grade: ≥95%. CAS No. 2072145-60-7. Molecular formula: C10H14IN3O5. Mole weight: 383.14.
5-Iodo-2'-C-methyluridine
5-Iodo-2'-C-methyluridine, renowned for its extraordinary biomedical capabilities, offering an innovative solution in research of viral infections. By impeding viral RNA research and development, this compound effectively hinders viral replication and subsequent dissemination. Synonyms: 5-Iodo-2'-C-methyl-1-β-D-ribofuranosyluracil; 1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione; 5-Iodo-2'-β-C-methyluridine. Grade: ≥95%. CAS No. 1203461-96-4. Molecular formula: C10H13IN2O6. Mole weight: 384.12.
5-Iodo-2'-deoxytubercidin
It is a derivative of 7-Iodo-7-deazadenine and is designed to be incorporated into DNA by using Vent(exo-) polymerase primers extension. Uses: Pharmaceutical intermediates. Synonyms: 4-Amino-5-iodo-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 2'-Deoxy-7-fluorotubercidin; 7-Iodo-7-deaza-2'-deoxyadenosine; 7-Deaza-2'-deoxy-7-iodoadenosine; 7-Iodo-2'-deoxy-7-carbaadenosine; (2R,3S,5R)-5-(4-Amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine. Grade: ≥95%. CAS No. 166247-63-8. Molecular formula: C11H13IN4O3. Mole weight: 376.15.
5-Iodo-2'-O-methylcytidine
5-Iodo-2'-O-methylcytidine, a nucleoside analogue (NSA), is a chemotherapeutic agent that induces neuronal differentiation. Synonyms: 5-Iodo-2'-O-methyl-cytidine; 5-I-2'-O-Me-Cr; Cytidine, 5-iodo-2'-O-methyl-; 4-Amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one. Grade: ≥95%. CAS No. 847650-69-5. Molecular formula: C10H14IN3O5. Mole weight: 383.14.
5-Iodo-3'-deoxy-3'-fluorouridine
5-Iodo-3'-deoxy-3'-fluorouridine is an antineoplastic compound specifically impeding the growth and multiplication of malignant cells. Remarkably, it finds extensive application across a spectrum of cancers including breast cancer, liver cancer and leukemia. Synonyms: 5-iodo-1-[(2R,3S,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-fluorooxolan-2-yl]pyrimidine-2,4-dione. Grade: ≥95%. CAS No. 2072145-21-0. Molecular formula: C9H10FIN2O5. Mole weight: 372.09.
5-Iodo-3-indolyl b-D-galactopyranoside
5-Iodo-3-indolyl β-D-galactopyranoside is a vital reagent used in biomedicine to detect β-galactosidase activity, an enzyme frequently employed as a reporter in molecular biology. Through hydrolysis, this compound generates a blue-colored precipitate, enabling researchers to visualize the expression of the lacZ gene and study genetic regulation, protein localization, and cellular processes related to drug development and disease progression. Synonyms: Purple b-D-Gal; 5-Iodo-1H-indol-3-yl β-D-galactopyranoside; 5-Iodo-3-indolyl β-D-galactoside; Iodo-Gal; 5-Iodo-3-indoxyl-beta-D-galactopyranoside; (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-((5-iodo-1H-indol-3-yl)oxy)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 36473-36-6. Molecular formula: C14H16INO6. Mole weight: 421.18.
5-Iodo-3-indolyl-b-D-galactopyranoside-6-sulfate sodium salt
5-Iodo-3-indolyl-b-D-galactopyranoside-6-sulfate sodium salt is a compound commonly used in the biomedical industry for staining and detecting galactosidase activity in cells and tissues. It offers high sensitivity and specificity allowing for the identification and analysis of cells expressing the enzyme. Synonyms: β-D-Galactopyranoside, 5-Iodo-1H-indol-3-yl, 6-(hydrogen sulfate) sodium salt. Molecular formula: C14H15INNaO9S. Mole weight: 523.24.
Important precursors for the synthesis of nucleotides, sugar nucleosides and as biologically active substances. Uses: Important precursors for the synthesis of nucleotides, sugar nucleosides and as biologically active substances. Synonyms: 5'-Deoxy-5'-iodoadenosine; 5'-Iodo-5'-deoxyadenosine. Grade: 98%. CAS No. 4099-81-4. Molecular formula: C10H12IN5O3. Mole weight: 377.14.
5-Iodo-7-(2-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a remarkable biomedical compound, showcasing exceptional potential for studying numerous ailments. Its profound antiviral and antitumor effects emanate from its exquisite ability to intricately influence vital intracellular mechanisms. Synonyms: 4-Amino-5-iodo-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; (2R,3R,4R,5R)-2-(4-amino-5-iodo-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-3,4-diol. Grade: ≥95%. CAS No. 847551-49-9. Molecular formula: C12H15IN4O4. Mole weight: 406.18.
5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative is a precursor to 5-Iodo-A-85380, which is a highly selective and potent ligand for AChR α4β2. It is used in radioiodination. Synonyms: (2S)-2-[[[5-(Trimethylstannyl)-3-pyridinyl]oxy]methyl]-1-azetidinecarboxylic acid, t-butyl ester. Grade: ≥98% by HPLC. CAS No. 213766-21-3. Molecular formula: C17H28N2O3Sn. Mole weight: 427.11.
5-Iodo-A-85380 dihydrochloride
5-Iodo-A-85380 dihydrochloride is the dihydrochloride salt of 5-Iodo-A-85380, which is a highly potent and subtype-selective agonist for α4β2 and α6β2 nicotinic acetylcholine receptors. It activates α-CTx-MII-sensitive and -insensitive components of [3H]dopamine release from rat striatal synaptosomes. Synonyms: Pyridine, 3-[(2S)-2-azetidinylmethoxy]-5-iodo-, hydrochloride (1:2); (S)-3-(Azetidin-2-ylmethoxy)-5-iodopyridine dihydrochloride; 3-[(2S)-2-Azetidinylmethoxy]-5-iodopyridine dihydrochloride. Grade: ≥99% by HPLC. CAS No. 1217837-17-6. Molecular formula: C9H13IN2OCl2. Mole weight: 363.03.
5-Iodo-A-85380 trifluoroacetate salt
5-Iodo-A-85380 trifluoroacetate salt is the salt of 5-Iodo-A-85380, which is a highly potent and subtype-selective agonist for α4β2 and α6β2 nicotinic acetylcholine receptors. Synonyms: Pyridine, 3-[(2S)-2-azetidinylmethoxy]-5-iodo-, 2,2,2-trifluoroacetate (2:5); Pyridine, 3-[(2S)-2-azetidinylmethoxy]-5-iodo-, trifluoroacetate (2:5); bis((S)-3-(azetidin-2-ylmethoxy)-5-iodopyridine) pentakis(2,2,2-trifluoroacetate). Grade: ≥95%. CAS No. 213764-92-2. Molecular formula: C9H11IN2O.5/2C2HF3O2. Mole weight: 575.15.
5-Iodoarabinouridine
5-Iodoarabinouridine, a biomedical compound, displays remarkable potential for research of various diseases. Exerting its influence as an RNA research and development inhibitor, this compound takes center stage in the arena of cancer research. Its proficiency lies in the selective targeting of RNA molecules, effectively curbing the malignant growth and propagation of cancer cells. Synonyms: 1-(β-D-Arabinofuranosyl)-5-iodouracil; NSC 82221; I-araU; 2,4(1H,3H)-Pyrimidinedione, 1-beta-D-arabinofuranosyl-5-iodo-; 1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione; 1-β-D-Arabinofuranosyl-5-iodo-2,4(1H,3H)-pyrimidinedione; Uracil, 1-β-D-arabinofuranosyl-5-iodo-; 1-β-D-Arabinofuranosyl-5-iodouracil; NSC 82221. Grade: ≥95%. CAS No. 3052-06-0. Molecular formula: C9H11IN2O6. Mole weight: 370.10.
5-Iodo-CDP
5-Iodo-CDP, a nucleotide analog utilized in experimental research and development for antiviral drugs, presents an inhibitory effect on a plethora of RNA viruses. From the notorious SARS-CoV to the insidious Lassa fever virus, this biomedicine product interferes with viral RNA synthesis and thereby suppresses viral replication. With its favorable outcomes in preclinical studies, this compound offers a considerable potential in the fight against viral infections. Synonyms: (5I-CDP); 5-Iodo-cytidine-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C9H14N3O11P2I (free acid). Mole weight: 529.07 (free acid).
5-Iodo-CTP
5-Iodo-CTP is an indispensable constituent extensively utilized in the biomedical sector for investigative proceedings, representing a tailored rendition of Cytidine Triphosphate (CTP), harboring an iodine constituent. Esteemed for its distinct attributes, this particular compound finds vast utility in delving into nucleotide modifications and their consequential influence on cellular mechanisms. Synonyms: (5I-CTP); 5-Iodo-cytidine-5'-triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C9H15N3O14P3I (free acid). Mole weight: 609.05 (free acid).
5-Iodocytidine
5-Iodocytidine is an intermediate for research in the field of nucleic acids and nucleic acid-protein interactions. Synonyms: 1-β-D-Ribofuranosyl-5-iodocytosine; 5-Iodo-cytidine; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one; 5-Iodo-ribo Cytidine. Grade: ≥95%. CAS No. 1147-23-5. Molecular formula: C9H12IN3O5. Mole weight: 369.11.
5-Iodo-cytidine
5-Iodo-cytidine, a potent nucleoside analog with antineoplastic properties, exhibits incredible efficacy in bladder cancer and leukemia treatment. By disturbing DNA synthesis, 5-Iodo-cytidine efficiently facilitates cell death. Its potential in halting cancer cell growth warrants further investigation. Grade: ≥ 98% by HPLC. Molecular formula: C9H12IN3O5. Mole weight: 369.11.
5-Iodocytidine 5'-triphosphate sodium salt
5-Iodocytidine 5'-triphosphate sodium salt is a highly significant recompound in the field of compound, exhibiting profound importance in diverse areas including DNA sequencing, mutagenesis studies, nucleic acid development, RNA labeling research, gene expression analysis and viral diagnostics. Synonyms: Sodium ((2R,3S,4R,5R)-5-(4-amino-5-iodo-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate; 59259-76-6. CAS No. 59259-76-6. Molecular formula: C9H15IN3O14P3. Mole weight: 609.05.
5-Iodo-dCTP
5-Iodo-dCTP is a crucial tool in biomedicine used for various applications. It serves as a labeled nucleotide analog and finds extensive use in DNA sequencing and labeling techniques. This product enables precise detection and identification of specific DNA sequences, aiding in genetic research, disease diagnostics, and drug development. It is commonly employed in studies related to cancer mutations and genetic disorders. Synonyms: 5I-dCTP; 5-Iodo-2'-deoxycytidine-5'-Triphosphate. Grade: ≥90% by AX-HPLC. CAS No. 31747-59-8. Molecular formula: C9H15N3O13P3I (free acid). Mole weight: 593.05 (free acid).
5-Iodo-dUMP
5-Iodo-dUMP is a critical compound extensively utilized in the biomedical field with pivotal function in obstructing DNA enhancement. It can impede the proliferation of malignant cells and thwarting the metastatic cascade. Synonyms: (5I-dUMP); 5-Iodo-2'-deoxyuridine-5'-monophosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 1763-02-6. Molecular formula: C9H12N2O8PI (free acid). Mole weight: 434.08 (free acid).
5-Iodo-dUTP
5-Iodo-dUTP is used in the synthesis of Texas Red-5-dUTP, a fluorescence-labelled nucleotide analog. Texas Red-5-dUTP is used diagnostically for detection of rearranged SS18 in formalin-fixed, paraffin-embedded synovial sarcoma. Synonyms: 5-Iodo-2'-deoxyuridine-5'-Triphosphate. Grade: ≥ 95% by HPLC. CAS No. 3731-55-3. Molecular formula: C9H14N2O14P3I (free acid). Mole weight: 594.04 (free acid).
5-Iodo-indirubin-3'-monoxime
5-Iodo-indirubin-3'-monoxime is a potent inhibitor of GSK-3β, CDK5/P25 and CDK1/cyclin B that competes with ATP to bind to the catalytic site of the kinase with IC50s of 9, 20 and 25 nM, respectively. Synonyms: 2H-Indol-2-one, 3-[1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-5-iodo-; 3-[3-(Hydroxyimino)-1,3-dihydro-2H-indol-2-ylidene]-5-iodo-1,3-dihydro-2H-indol-2-one. Grade: ≥95%. CAS No. 331467-03-9. Molecular formula: C16H10IN3O2. Mole weight: 403.17.
5-Iodo-N4-DMF-2'-deoxycytidine
5-Iodo-N4-DMF-2'-deoxycytidine is a highly potent and efficacious antiviral compound, finding application in the therapeutic research of diverse viral affections, notably those stemming from DNA viruses. Its exceptional effectiveness becomes evident in research of infections caused by herpes simplex virus (HSV) and cytomegalovirus (CMV). Leveraging its distinctive molecular composition, this compound exerts its therapeutic action as a nucleoside analog, inducing disruption of viral replication mechanisms and consequentially impeding the development of viral pathologies. Synonyms: N4-DMF-5-I-dC; Cytidine, 2'-deoxy-N-[(dimethylamino)methylene]-5-iodo-; N-(Dimethylaminomethylene)-5-iodo-2'-deoxycytidine. Grade: ≥97% by HPLC. CAS No. 717876-93-2. Molecular formula: C12H17IN4O4. Mole weight: 408.20.
5'-Iodoresiniferatoxin
5'-Iodoresiniferatoxin is a very potent and strong competitive antagonist of the transient receptor potential vanilloid 1 (TRPV1) receptor. It is derived from resiniferatoxin (RTX), which is produced by the Moroccan succulent Euphorbia resinifera. It is iodinated at the 5-position and can be prepared from RTX by electrophilic aromatic substitution. It binds to TRPV1 (VR1) receptors expressed in HEK293 cells with Kd value of 4.3 nM and Ki value of 5.8 nM. It binds to the VR1 receptor with high affinity but does not induce RTX- or capsaicin-like effects in Xenopus laevis oocytes expressing VR1. It is 40-fold more potent than capsazepine. Synonyms: 5-I-RTX; 5'-IRTX; 6,7-Deepoxy-6,7-didehydro-5-deoxy-21-dephenyl-21-(phenylmethyl)-daphnetoxin,20-(4-hydroxy-5-iodo-3-methoxybenzeneacetate). Grade: ≥98% by HPLC. CAS No. 535974-91-5. Molecular formula: C37H39IO9. Mole weight: 754.60.
5-Iodotubercidin
It is an adenosine kinase inhibitor, protein kinase inhibitor and activator, nucleoside transporter inhibitor. Uses: An analogue of the antibiotic tubercidin, a pyrrolo[2,3-d]pyrimidine nucleoside antibiotic. a potent inhibitor of adenosine kinase from rat or guinea pig brain. inhibits uptake of 3h-adenosine into brain slices. Synonyms: 7-Iodo-tubercidin; 7-Deaza-7-iodoadenosine; 4-Amino-5-iodo-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine; NSC 113939; 5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 7-iodo-7-deazaadenosine; 7-deaza-7-I-Ar. Grade: ≥95%. CAS No. 24386-93-4. Molecular formula: C11H13IN4O4. Mole weight: 392.15.
5-Iodo-UDP
5-Iodo-UDP is an extensively utilized chemical compound assuming as a precursor for synthesizing diverse pharmaceutical intermediates and therapeutic compounds. Its substantial involvement in anti-cancer developments, coupled with its potentiality to study manifold neurological maladies, underscores its significance. Synonyms: (5I-UDP); 5-Iodo-uridine-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C9H13N2O12P2I (free acid). Mole weight: 530.06 (free acid).
5-Iodo-UMP
5-Iodo-UMP is an indispensable compound, pragmatically utilized for research of viral infections and specific malignancies. This pivotal compound exerts substantial influence by restraining the proliferation and duplication of neoplastic cells. Moreover, its possession of potent antiviral characteristics renders it an integral constituent within the formulation of antivirals. Synonyms: (5I-UMP); 5-Iodo-uridine-5'-monophosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C9H12N2O9PI (free acid). Mole weight: 450.08 (free acid).
5-Iodouridine
It is a Rho-GTPase cell protein inhibitor. Synonyms: NSC 523375; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione; 2,4-Dihydroxy-5-iodo-1-β-D-ribofuranosylpyrimidine; 5-Iodo-1-(β-D-ribofuranosyl)uracil; 5-Iodo Uridine. Grade: ≥95%. CAS No. 1024-99-3. Molecular formula: C9H11IN2O6. Mole weight: 370.10.
5-Iodo-uridine
5-Iodo-uridine is a nucleoside analog that has shown promise in the treatment of viral infections such as hepatitis B and C. It works by inhibiting viral replication through its interference with the nucleic acid synthesis of the virus. Additionally, it has also been investigated for potential use in cancer treatment due to its ability to induce apoptosis in cancer cells. Grade: ≥ 98% by HPLC. Molecular formula: C9H11IN2O6. Mole weight: 370.1.
5-Iodo-UTP
5-Iodo-UTP is a modified nucleotide used to detect RNA expression and to label RNA for hybridization. It is commonly used in biomedical research such as in vitro transcription for the synthesis of labeled RNA and in RNA-protein interaction assays. Synonyms: (5I-UTP); 5-Iodo-uridine-5'-triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 34198-43-1. Molecular formula: C9H14N2O15P3I (free acid). Mole weight: 610.04 (free acid).
5-(isopentenylaminomethyl)-2'-O-methyluridine
5-(Isopentenylaminomethyl)-2'-O-methyluridine, an essential nucleoside analog, holds a pivotal position in RNA modification research for its impact on RNA function and structure. Besides, it excites the scientific community with its reported antiviral efficacy against HIV. Researchers can leverage this potent tool in Unlocking the secrets of RNA modification and curbing viral infections. Synonyms: Uridine, 2'-O-methyl-5-[[(3-methyl-2-butenyl)amino]methyl]-. CAS No. 872710-80-0. Molecular formula: C16H25N3O6. Mole weight: 355.39.
5-(isopentenylaminomethyl)-2-thiouridine
5-(Isopentenylaminomethyl)-2-thiouridine, a modified nucleoside utilized in RNA research within the biomedical sector, has exhibited a notable influence over translation regulation. Its promising implications in both cancer and viral infections have experts exploring its therapeutic potential towards numerous maladies. Alongside its role in RNA research, 5-(Isopentenylaminomethyl)-2-thiouridine possesses the power to revolutionize the treatment methods of various diseases. Synonyms: Uridine, 5-[[(3-methyl-2-butenyl)amino]methyl]-2-thio-. CAS No. 872710-78-6. Molecular formula: C15H23N3O5S. Mole weight: 357.43.
5-(isopentenylaminomethyl)uridine
5-(Isopentenylaminomethyl)uridine is a modified nucleoside used primarily in biomedical research for its ability to enhance RNA stability and regulate protein translation. It has also shown potential in the treatment of certain cancers and viral infections. Synonyms: Uridine, 5-[[(3-methyl-3-butenyl)amino]methyl]-. CAS No. 872710-76-4. Molecular formula: C15H23N3O6. Mole weight: 341.36.