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Basidalin
Basidalin is produced by the strain of Leucoagaricus naucina NZ157. It has the ability of anti-gram-positive bacteria, negative bacteria and inhibition of mouse leukemia L-1210 cell. Synonyms: (Z)-4-Amino-5-(formylmethylene)-2(5H)-furanone; (Z)-(3-Amino-5-oxo-2(5H)-furanylidene)acetaldehyde; Acetaldehyde, (3-amino-5-oxo-2(5H)-furanylidene)-. Molecular formula: C6H5NO3. Mole weight: 139.11.
Bassianin
Bassianin is a fungal metabolite isolated from Beauveria bassiana. Bassianin is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.91 and 12.12 μM, respectively. Grades: >95% by HPLC. CAS No. 54278-73-8. Molecular formula: C23H25NO5. Mole weight: 395.45.
Bassianolide
It is a cyclooctadepsipeptide antibiotic isolated from the entomopathogenic fungi. It is one of the active components of beauveria bassiana biocontrol products. It has insecticidal properties. Synonyms: (-)-Bassianolide; NSC 321804; BASS; cyclo[N(Me)Leu-D-OVal-N(Me)Leu-D-OVal-N(Me)Leu-D-OVal-N(Me)Leu-D-OVal]; cyclo[N-methyl-L-leucyl-N-oxa-D-valyl-N-methyl-L-leucyl-N-oxa-D-valyl-N-methyl-L-leucyl-N-oxa-D-valyl-N-methyl-L-leucyl-N-oxa-D-valyl]. Grades: >95% by HPLC. CAS No. 64763-82-2. Molecular formula: C48H84N4O12. Mole weight: 909.20.
Baumycin A1
Baumycin A1 is produced by the strain of Streptomyces sp. ME 130-A4. Synonyms: 5,12-Naphthacenedione, 8-acetyl-10-((3-amino-2,3,6-trideoxy-4-O-(3-hydroxy-1-(2-hydroxy-1-methylethoxy)butyl)-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-. CAS No. 64314-28-9. Molecular formula: C34H43NO13. Mole weight: 673.70.
Baumycin B1
Baumycin B1 is produced by the strain of Streptomyces sp. ME 130-A4. Synonyms: 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-8-acetyl-10-((3-amino-4-O-(1-(1-carboxyethoxy)-3-hydroxybutyl)-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-; 3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-4-o-[1-(1-carboxyethoxy)-3-hydroxybutyl]-2,3,6-trideoxyhexopyranoside. CAS No. 64253-72-1. Molecular formula: C34H41NO14. Mole weight: 687.69.
Baumycin C1
Baumycin C1, an impurity of Daunorubicin and Doxorubicin, is an anthracycline antibiotic isolated from Streptomyces coeruleorubidus. Baumycin C1 shows antitumor activity. Synonyms: N-((2S,3S,4S,6R)-6-(((1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl)oxy)-3-hydroxy-2-methyltetrahydro-2H-pyran-4-yl)formamide; N-Formyldaunorubicin; NSC 227012; 5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-((2,3,6-trideoxy-3-(formylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, (8S-cis)-; (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[(3-(formylamino)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-5,12-naphthacenedione. Grades: ≥95%. CAS No. 63084-42-4. Molecular formula: C28H29NO11. Mole weight: 555.53.
Bax inhibitor peptide, negative control
A negative control peptide for the Bax inhibitor peptide V5, which inhibits Bax translocation to mitochondria and Bax-mediated apoptosis in vitro. Synonyms: L-isoleucyl-L-prolyl-L-methionyl-L-isoleucyl-L-lysine. Grades: >98%. CAS No. 1315378-74-5. Molecular formula: C28H52N6O6S. Mole weight: 600.82.
BE-10988 is a topoisomerase-II inhibitor produced by Str. sp. BA 10988. It has the activity of inhibiting P388 murine leukemia cells. It inhibits P388 (P388S), vincristine-doxorubicin-resistant P388 (P388/VCR) and doxorubicin-resistant P388 (P388/MDR) cells with IC50 (μmol/L) of 0.5, 0.4, 2.0, respectively. CAS No. 135261-89-1. Molecular formula: C13H10N4O3S. Mole weight: 302.31.
BE-12406 A
BE-12406 A is an antitumor antibiotic produced by Streptomyces rutrersensis subsp. castelarensis. It has the activity of inhibiting murine P388 leukemia cells (IC50 is 0.8 μmol/L), and has the same activity against vincristine-doxorubicin resistant strains (P388/VCR) (IC50 is 0.2 μmol/L). It can inhibit the growth of S480 ascites carcinoma in mice. Synonyms: BE 12406A; 6H-Benzo(d)naphtho(1,2-b)pyran-6-one, 12-((6-deoxy-alpha-L-mannopyranosyl)oxy)-1-hydroxy-10-methoxy-8-methyl-. CAS No. 132417-96-0. Molecular formula: C25H24O9. Mole weight: 468.45.
BE-12406 B
BE-12406 B is an antitumor antibiotic produced by Streptomyces rutrersensis subsp. castelarensis. It has the activity of inhibiting murine P388 leukemia cells (IC50 is 7 μmol/L), and has the same activity against vincristine-doxorubicin resistant strains (P388/VCR) (IC50 is 7 μmol/L). It can inhibit the growth of S480 ascites carcinoma in mice. Synonyms: 12-((6-Deoxyhexopyranosyl)oxy)-1,10-dihydroxy-8-methyl-6H-benzo(d)naphtho(1,2-b)pyran-6-one. CAS No. 132417-97-1. Molecular formula: C24H22O9. Mole weight: 454.43.
BE-18257A
BE-18257 A is an endothelin binding inhibitor produced by Streptomyces misakiensis. Synonyms: Cyclo(valyl-leucyl-tryptophyl-glutamyl-alanyl); Cyclo(L-alanyl-D-valyl-L-leucyl-D-tryptophyl-D-alpha-glutamyl). CAS No. 136553-73-6. Molecular formula: C30H42N6O7. Mole weight: 598.69.
BE-18257B
BE-18257 B is an endothelin binding inhibitor produced by Streptomyces misakiensis. Synonyms: Cyclo(L-alanyl-D-alloisoleucyl-L-leucyl-D-tryptophyl-D-alpha-glutamyl); LS-55815. Molecular formula: C31H44N6O7. Mole weight: 612.72.
BE-19412A
BE-19412A is an antitumor antibiotic extracted from the culture medium of Streptomyces sp. A19412. It is toxic to mouse and human tumor cells such as P388, Ehrlich, DLD-1, PC-13, MKN-45 and Colon 26, with IC50 of 0.9-5.4 μg/mL, and can prolong the survival time of CDF1 mice with Ehrlich cancer. Synonyms: LS-94141. CAS No. 173774-90-8. Molecular formula: C28H22ClNO8. Mole weight: 535.93.
BE-19412B
BE-19412B is an antitumor antibiotic extracted from the culture medium of Streptomyces sp. A19412. It is toxic to mouse and human tumor cells such as P388, Ehrlich, DLD-1, PC-13, MKN-45 and Colon 26, with IC50 of 0.9-5.4 μg/mL, and can prolong the survival time of CDF1 mice with Ehrlich cancer. Synonyms: LS-94140. CAS No. 173774-91-9. Molecular formula: C30H26ClNO8. Mole weight: 563.98.
BE-23372M
BE-23372M is a protein tyrosine kinase inhibitor produced by Rhizoctonia solani. It has strong inhibition of epidermal growth factor (EGF) receptor kinase activity. Synonyms: (3E)-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)furan-2(3H)-one. CAS No. 145588-13-2. Molecular formula: C17H12O6. Mole weight: 312.27.
BE-29602
BE-29602 is a papulacandin antibiotic produced by Fusarium sp. F296O2. It has activity against Candida, Saccharomyces cerevisiae and other fungi, with an MIC of 0.20-0.7 μg/mL. It is cytotoxic and has an IC50 of 21 μg/mL to P388 murine leukemia cells. Molecular formula: C45H62O16. Mole weight: 858.96.
BE-31405
BE-31405 is an antifungal antibiotic produced by Penicillum minioluteum F31405. It has activity against pathogenic fungi such as Candida albicans and Cryptococcus neoformans (MIC 3.13-6.25 μg/mL), and has no cytotoxicity to mammalian cells (such as P388 murine leukemia, etc.). Molecular formula: C28H36O10. Mole weight: 532.58.
BE-32030A
BE-32030A is an antitumor antibiotic produced by Nocardia sp. A32030. It has inhibitory effect on the growth of P388, DLD-h PC-13 and MKN-45 tumor cells. Synonyms: BE-32030 A. CAS No. 161589-09-9. Molecular formula: C39H61N5O10. Mole weight: 759.93.
BE-32030B
BE-32030B is an antitumor antibiotic produced by Nocardia sp. A32030. It has inhibitory effect on the growth of P388, DLD-h PC-13 and MKN-45 tumor cells. Synonyms: Lysine, N(sup 2)-((4,5-dihydro-2-(2-hydroxyphenyl)-4-methyl-4-oxazolyl)carbonyl)-N(sup 6)-hydroxy-N(sup 6)-(1-oxotetradecyl)-, 3-((hexahydro-1-hydroxy-2-oxo-1H-azepin-3-yl)amino)-1-methyl-3-oxopropyl ester; BE-32030 B. CAS No. 161589-10-2. Molecular formula: C41H65N5O10. Mole weight: 787.98.
BE-32030C
BE-32030C is an antitumor antibiotic produced by Nocardia sp. A32030. It has inhibitory effect on the growth of P388, DLD-h PC-13 and MKN-45 tumor cells. Synonyms: BE-32030 C. CAS No. 161589-11-3. Molecular formula: C43H67N5O10. Mole weight: 814.02.
BE-32030D
BE-32030D is an antitumor antibiotic produced by Nocardia sp. A32030. It has inhibitory effect on the growth of P388, DLD-h PC-13 and MKN-45 tumor cells. Synonyms: BE-32030 D. CAS No. 161589-12-4. Molecular formula: C39H61N5O11. Mole weight: 775.93.
BE-32030E
BE-32030E is an antitumor antibiotic produced by Nocardia sp. A32030. It has inhibitory effect on the growth of P388, DLD-h PC-13 and MKN-45 tumor cells. Synonyms: BE-32030 E. CAS No. 161589-13-5. Molecular formula: C41H63N5O10. Mole weight: 785.97.
BE-40644
BE-40644 is an inhibitor of human Thioredoxin system produced by Actinoplanes sp. A40644. It can inhibit the growth of several tumor cells. Synonyms: 4,4,6aalpha,12bbeta-Tetramethyl-9-(hydroxymethyl)-1,3,4,4aalpha,5,6,6a,12,12aalpha,12b-decahydro-2H-benzo[a]xanthene-8,11-dione. CAS No. 172923-88-5. Molecular formula: C22H30O4. Mole weight: 358.47.
BE-40665D
BE-40665D is an antibiotic produced by Actinoplanes sp. A4O665. It has moderate anti-gram-positive bacteria activity and has no effect on gram-positive bacteria. CAS No. 183241-67-0. Molecular formula: C22H21BrO7. Mole weight: 477.30.
BE-43472B
BE-43472B is a bisanthraquinone antibiotic isolated from a streptomycete strain. It has antibacterial activity against MSSA, MRSA, TRSA and VRE. Synonyms: (8S,9S,9aR,18aS,20R)-8,9-Dihydro-4,6,8,16-tetrahydroxy-8,14,20-trimethyl-18a,9-(epoxymethano)-18aH-dianthra[1,2-b:4'a,10'-d]furan-5,12,17(7H)-trione; 18a,9-(Epoxymethano)-18aH-dianthra[1,2-b:4'a,10'-d]furan-5,12,17(7H)-trione, 8,9-dihydro-4,6,8,16-tetrahydroxy-8,14,20-trimethyl-, (8S,9S,9aR,18aS,20R)-. CAS No. 180027-59-2. Molecular formula: C32H24O9. Mole weight: 552.53.
BE-52440A
BE-52400A is a cytotoxicity produced by Streptomyces sp. A52400. It has anti-proliferative effect on mouse tumor cell lines such as P388 leukemia and colon 26 colon and human tumor cell lines such as DLD1 (colon), PC-13 (lung), MKN-45 (stomach), etc., with IC50 of 6.1, 2.1, 0.47, 3.9, 0.88 μg/mL. CAS No. 195051-22-0. Molecular formula: C34H34O14S. Mole weight: 698.69.
BE-52440B
BE-52400B is a cytotoxicity produced by Streptomyces sp. A52400. It has anti-proliferative effect on mouse tumor cell lines such as P388 leukemia and colon 26 colon and human tumor cell lines such as DLD1 (colon), PC-13 (lung), MKN-45 (stomach), etc., with IC50 of 1.1, 3.4, 0.69, 2.6, 2.9 μg/mL. CAS No. 195051-23-1. Molecular formula: C33H34O13S. Mole weight: 670.68.
BE-54238A
BE-54238A is a cytotoxic agent produced by Streptomyces sp. A54238. It has anti-proliferative effects on tumor cells such as P388, DLD4, PC-13, MKN-45, colon 26, etc., with IC50 of (μg/mL) 9.1, 3.5, 11.3, 8.1, 8.6. Synonyms: BE-54238 A; (-)-Be-54238a; 2-(5-Hydroxy-11-(1-hydroxyethyl)-4-methyl-6-oxo-1,4,6,9,10,11-hexahydro-2H-benzo(cd)pyrano(3,4-g)pyrrolo(1,2-a)indol-2-yl)acetic acid. CAS No. 205433-26-7. Molecular formula: C22H23NO6. Mole weight: 397.42.
BE-54238B
BE-54238B is a cytotoxic agent produced by Streptomyces sp. A54238. It has anti-proliferative effects on tumor cells such as P388, DLD4, PC-13, MKN-45, colon 26, etc., with IC50 of (μg/mL) 58.2, 10.1, 53.2, 45.6, 20.5. Synonyms: BE-54238 B. CAS No. 205433-27-8. Molecular formula: C22H21NO6. Mole weight: 395.40.
Beauvericin
Beauvericin is produced by the strain of Streptomyces sp. Ba cyclic depsipeptide isolated from several fungal genera, notably beauveria and fusarium; exhibits broad antifungal, antibacterial, antiprotozoan and insecticidal activities; exhibits ionophoric properties, and inhibits acyl-coa:Cholesterol acyltransferase activity; induces apoptosis by elevating intracellular calcium levels. Synonyms: Cyclo(-D-alpha-hydroxyisovaleryl-N-Me-Phe)3. Grades: >97% by HPLC. CAS No. 26048-05-5. Molecular formula: C45H57N3O9. Mole weight: 783.95.
Beauveriolide I
Beauveriolide I is produced by the strain of Beauveria sp. FO-6979. The effect of I and III can inhibit the formation of Lipid droplet. 10μmol/L can reduce the number and size of the cytolipid droplet in the macrophage but it is not cytotoxic to the macrophages. Synonyms: CHEMBL516093; SCHEMBL15474166. CAS No. 154491-55-1. Molecular formula: C27H41N3O5. Mole weight: 487.63.
Beauveriolide III
Beauveriolide III is produced by the strain of Beauveria sp. FO-6979. The effect of I and III can inhibit the formation of Lipid droplet. 10μmol/L can reduce the number and size of the cytolipid droplet in the macrophage but it is not cytotoxic to the macrophages. Synonyms: CHEMBL409855; SCHEMBL16174055. CAS No. 221111-70-2. Molecular formula: C27H41N3O5. Mole weight: 487.63.
Belactosin A
Belactosin A is produced by the strain of Streptomyces sp. No antibacterial activity. A inhibits the IC50 of HeLa S3 cells is 51μmol/L. Synonyms: (alphaS,1S)-alpha-(L-Alanylamino)-2beta-[[[(2R)-3alpha-[(S)-sec-butyl]-4-oxooxetane-2beta-yl]carbonyl]amino]cyclopropane-1beta-propionic acid. Molecular formula: C17H27N3O6. Mole weight: 369.41.
Belactosin C
Belactosin C is produced by the strain of Streptomyces sp. No antibacterial activity. C inhibits the IC50 of HeLa S3 cells is 200μmol/L. Synonyms: SCHEMBL3448978; CHEMBL1783833. CAS No. 189871-55-4. Molecular formula: C16H27N3O6. Mole weight: 357.40.
Benadrostin
Benadrostin is produced by the strain of Streptomyces flavovirens MH499-O'Flc. Poly-(adp-Ribose) synthetase was inhibited with IC50 of 35μmol/L. Synonyms: 8-Hydroxy-2H-1,3-benzoxazine-2,4(3H)-dione; 2H-1,3-Benzoxazine-2,4(3H)-dione, 8-hydroxy-. CAS No. 117241-60-8. Molecular formula: C8H5NO4. Mole weight: 179.13.
Benanomicin A
Benanomicin A is produced by the strain of Actinomadura sp. MH193-16F4. A and B have anti-candida, Cryptococcus neoforme, Saccharomyces cerevisiae and other fungal activities, while A has stronger activity. Xylose benamycin A and B showed similar or slightly stronger activity against candida, yeast and Cryptococcus, but decreased activity against aspergillus. The antifungal activity of 2-demethylbenamycin was similar to that of xylose Benamycin A. The synthesized 7-methoxybenamycin had little antifungal activity, but showed inhibitory activity of glucosinolase (EC 3.2.1.20) with IC50 of 60μg/mL. Synonyms: D-Alanine, N-((5-((6-deoxy-3-O-beta-D-xylopyranosyl-beta-D-galactopyranosyl)oxy)-5,6,8,13-tetrahydro-1,6,9,14-tetrahydroxy-11-methoxy-3-methyl-8,13-dioxobenzo(a)naphthacen-2-yl)carbonyl)-, (5S-trans)-. CAS No. 116249-65-1. Molecular formula: C39H41NO19. Mole weight: 827.74.
Benanomicin B
Benanomicin B is produced by the strain of Actinomadura sp. MH193-16F4. A and B have anti-candida, Cryptococcus neoforme, Saccharomyces cerevisiae and other fungal activities, while A has stronger activity. Xylose benamycin A and B showed similar or slightly stronger activity against candida, yeast and Cryptococcus, but decreased activity against aspergillus. The antifungal activity of 2-demethylbenamycin was similar to that of xylose Benamycin A. The synthesized 7-methoxybenamycin had little antifungal activity, but showed inhibitory activity of glucosinolase (EC 3.2.1.20) with IC50 of 60μg/mL. Synonyms: Pradimicin C; D-Alanine, N-((5-((4-amino-4,6-dideoxy-3-O-beta-D-xylopyranosyl-beta-D-galactopyranosyl)oxy)-5,6,8,13-tetrahydro-1,6,9,14-tetrahydroxy-11-methoxy-3-methyl-8,13-dioxobenzo(a)naphthacen-2-yl)carbonyl)-. CAS No. 116249-66-2. Molecular formula: C39H42N2O18. Mole weight: 826.75.
Benarthin
Benarthin is produced by the strain of Streptomyces xanthophaeus MJ 244-SF1. It inhibited the activity of pyroglutaminase and competed with the substrate, and the inhibitory constant Ki and Km was 1.2x10-6 mol/L and 3.3x10-5 mol/L, respectively. Synonyms: N-(N(sup 2)-(2,3-Dihydroxybenzoyl)-L-arginyl)-L-threonine; L-Threonine, N-(N2-(2,3-dihydroxybenzoyl)-L-arginyl)-. CAS No. 143651-45-0. Molecular formula: C17H25N5O7. Mole weight: 411.41.
Benastatin A
Benastatin A is produced by the strain of Streptomyces sp. MI 384-DF12. It can inhibit glutathione transferase (GST) activity. Synonyms: Benzo(a)naphthacene-2-carboxylic acid, 8,13-dihydro-13,13-dimethyl-8-oxo-3-pentyl-1,7,9,11-tetrahydroxy-. CAS No. 138968-85-1. Molecular formula: C30H28O7. Mole weight: 500.54.
Benastatin B
Benastatin B is produced by the strain of Streptomyces sp. MI 384-DF12. It can inhibit glutathione transferase (GST) activity. Synonyms: Benzo(a)naphthacene-2-carboxylic acid, 5,6,8,13-tetrahydro-13,13-dimethyl-8-oxo-3-pentyl-1,7,9,11-tetrahydroxy-. CAS No. 138968-86-2. Molecular formula: C30H30O7. Mole weight: 502.55.
Benastatin C
Benastatin C is produced by the strain of Streptomyces sp. MI 384-DF12. It can inhibit glutathione transferase (GST) activity. Synonyms: 13,13-Dimethyl-3-pentyl-1,7,9,11-tetrahydroxybenzo(a)naphthacen-8(13H)-one; Benzo(a)naphthacen-8(13H)-one, 1,7,9,11-tetrahydroxy-13,13-dimethyl-3-pentyl-. CAS No. 150151-88-5. Molecular formula: C29H28O5. Mole weight: 456.53.
Benesudon
Benesudon is produced by the strain of Mollisia benesuada. MIC 2.5-10μg/mL was found to be resistant to gram-positive bacteria, negative bacteria, yeast and fungi. It's cytotoxic and its IC50 of L1 210, RBL, BHK21 and B1 6-F1 cells is 1-2μg/mL. CAS No. 189506-36-3. Molecular formula: C16H24O5. Mole weight: 296.36.
Benzanthrin A
Benzanthrin A is produced by the strain of Nocardia lurida. It mainly has the activity of anti-gram-positive bacteria. B is 10 times more toxic to 9ASK cells than A. CAS No. 103523-24-6. Molecular formula: C35H42N2O9. Mole weight: 634.71.
Benzanthrin B
Benzanthrin B is produced by the strain of Nocardia lurida. It mainly has the activity of anti-gram-positive bacteria. B is 10 times more toxic to 9ASK cells than A. CAS No. 103618-16-2. Molecular formula: C35H42N2O9. Mole weight: 634.71.
Benzastatin A
Benzastatin A is produced by the strain of Streptomyces nitrosporeas 30643. All the components can inhibit the lipid peroxidation activity of rat liver microsomes. Molecular formula: C19H28N2O2. Mole weight: 316.44.
Benzastatin B
Benzastatin B is produced by the strain of Streptomyces nitrosporeas 30643. All the components can inhibit the lipid peroxidation activity of rat liver microsomes. Molecular formula: C18H26N2O. Mole weight: 286.41.
Benzastatin C
Benzastatin C is produced by the strain of Streptomyces nitrosporeas 30643. All the components can inhibit the lipid peroxidation activity of rat liver microsomes. Synonyms: CHEBI:65483; Q27133927. Molecular formula: C19H27ClN2O2. Mole weight: 350.88.
Benzastatin D
Benzastatin D is produced by the strain of Streptomyces nitrosporeas 30643. All the components can inhibit the lipid peroxidation activity of rat liver microsomes. Molecular formula: C19H28N2O3. Mole weight: 332.44.
Benzastatin H
Benzastatin H is produced by the strain of Streptomyces nitrosþoreas 30643. H and I can protect nerve cells from glutamate toxicity with EC50 of 30.3 and 31.6 μmol/L, which is similar to ldebenone, but its cytotoxicity (lC50 > 200 μmol/L) is much lower than that of lC50 4.0 μmol/L. Molecular formula: C18H26N2O2. Mole weight: 302.41.
Benzastatin I
Benzastatin I is produced by the strain of Streptomyces nitrosþoreas 30643. H and I can protect nerve cells from glutamate toxicity with EC50 of 30.3 and 31.6 μmol/L, which is similar to ldebenone, but its cytotoxicity (lC50 > 200 μmol/L) is much lower than that of lC50 4.0 μmol/L. Molecular formula: C18H26N2O2. Mole weight: 302.41.
Benzathine penicilline
Benzathine penicilline is an antibiotic useful for the treatment of a number of bacterial infections, which is also known as benzathine penicillin G. It has bacteriostatic and bacteriocidal actions against most Gram-positive bacteria and Gram-negative cocci. Uses: Anti-bacterial agents. Synonyms: Debecillin; Pendepon; Penduran. Grades: >98%. CAS No. 1538-09-6. Molecular formula: C48H56N6O8S2. Mole weight: 909.12.
Synonyms: (2S,3S)-H-Apns-OH HCl. Grades: ≥ 99% by HPLC. CAS No. 62023-62-5. Molecular formula: C10H13NO3. Mole weight: 195.22.
Benzomalvin A
It is produced by the strain of Penicillum sp. Benzomalvin A was isolated as an active inhibitor of substance P binding to mammalian neurokinin NK1 receptors. Benzomalvin A is a fungal metabolite produced by Penicillium. It inhibits yeast α-glucosidase in vitro with IC50 of 383.2 μM. Benzomalvin A also acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P to guinea pig, rat, and human NK1 (Kis = 12, 42, and 43 μM, respectively). Synonyms: (-)-Benzomalvin A; Enzomalvin-A. Grades: ≥95%. CAS No. 157047-96-6. Molecular formula: C24H19N3O2. Mole weight: 381.43.
Benzomalvin B
It is produced by the strain of Penicillum sp. Benzomalvin B was isolated as an active inhibitor of substance P binding to mammalian neurokinin NK1 receptors. Benzomalvin B is a fungal metabolite produced by Penicillium. It acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P by 24% in vitro when used at a concentration of 100 μg/ml. Synonyms: (-)-Benzomalvin B; Enzomalvin-B. Grades: ≥95%. CAS No. 157047-97-7. Molecular formula: C24H17N3O2. Mole weight: 379.41.
Benzomalvin C
Benzomalvin C is produced by the strain of Penicillum sp. It is a neurokinin NK1 receptor antagonist and IDO inhibitor. Synonyms: 6'-methyl-3-phenyl-13'h-spiro[oxirane-2,7'-quinazolino[3,2-a][1,4]benzodiazepine]-5',13'(6'h)-dione; GK3542; GK 3542; GK-3542; benzomalvin C. Grades: >98%. CAS No. 157047-98-8. Molecular formula: C24H17N3O3. Mole weight: 395.41.
One of the most convenient coupling reagents for peptide synthesis without carcinogenic by-products. It replaces BOP reagent. This is especially suitable for solid-phase peptide synthesis, avoids racemization. Synonyms: PyBOPl; BOPP; (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate; ((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate; bopp; MFCD00077411; PyBOP(R); benzotriazol-1-yl-oxytripyrrolidinphosphonium hexafluorophosphate. Grades: ≥ 99% (HPLC). CAS No. 128625-52-5. Molecular formula: C18H28F6N6OP2. Mole weight: 520.39.
Benzoxazomycin
Benzoxazomycin is an ansa antibiotic produced by Str. sp. MJ672-m3. It can inhibit the growth of tumor cells such as NCI-H522, NCI-H469, OVCAR-5, St-4 and BSY-1. Molecular formula: C36H48N2O8. Mole weight: 636.77.