BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| AMP-CP | AMP-CP is a non-hydrolytic analogue of ADP and a starting structure in the synthesis of α/β hydrolysis-resistant tri- and polyphosphates. It is also an inhibitor of CD73. Uses: Enzyme inhibitors. Synonyms: Adenosine 5'-methylenediphosphate; MethADP; phosphomethylphosphonic acid adenosyl ester; AMP-CP; Adenosine, 5'-(trihydrogen methylenebis(phosphonate)); Adenosine 5'-(hydrogen (phosphonomethyl)phosphonate); ALPHA,BETA-METHYLENEADENOSINE 5'-DIPHOSPHATE; 104835-70-3; AMPCP; CHEBI:40730; 0T2A5439OE; [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]methylphosphonic acid; alpha,beta-Methyleneadenosine 5'-diphosphate sodium salt; 5'-O-[hydroxy(phosphonomethyl)phosphoryl]adenosine; MethADP (Adenosine 5'-(alpha,beta-methylene)diphosphate). Grade: ≥ 95% by HPLC. CAS No. 104835-70-3. Molecular formula: C11H17N5O9P2 (free acid). Mole weight: 425.2(free acid). |  |
| Amperozide hydrochloride | Amperozide is an atypical antipsychotic that displays high affinity for 5-HT 2 receptors (K i=26 nM) and low affinity for D2 receptors. Synonyms: 4-(4,4-Bis(p-fluorophenyl)butyl)-N-ethyl-1-piperazinecarboxamide; FG 5606; FG-5606. Grade: >99 %. CAS No. 75558-90-6. Molecular formula: C23H29F2N3O. Mole weight: 401.50. | |
| Amphethinile | Amphethinile is an anti-tubulin agent. The affinity constant for the association (Ka) of Amphethinile with tubulin is 1.3 μM. Synonyms: Amphetinile; CRC 82-07; 2-Amino-3-cyano-5-(phenylthio)indole; NSC-383336. CAS No. 91531-98-5. Molecular formula: C15H11N3S. Mole weight: 265.33. | |
| Amphotericin B methyl ester | Amphotericin B methyl ester, a methyl ester derivative of the polyene antibiotic Amphotericin B, is a cholesterol binding compound with significant antifungal activity. It disrupts the production of HIV-1 particles and effectively inhibits HIV-1 replication. Synonyms: Methylamphotericin B; Amphotericin B Monomethyl Ester; Methyl (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate. Grade: ≥95%. CAS No. 36148-89-7. Molecular formula: C48H75NO17. Mole weight: 938.11. | |
| Amphotericin B methyl ester hydrochloride | Amphotericin B methyl ester hydrochloride, a methyl ester derivative of the polyene antibiotic Amphotericin B, is a cholesterol binding compound with significant antifungal activity. It disrupts the production of HIV-1 particles and effectively inhibits HIV-1 replication. Synonyms: AME hydrochloride; NSC 252624; Methyl (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate hydrochloride (1:1). Grade: ≥98%. CAS No. 35375-29-2. Molecular formula: C48H76ClNO17. Mole weight: 974.57. | |
| Ampicillin benzathine | Benzathine Ampicillin is an impurity of Ampicillin, which is a broad-spectrum antibiotic used to prevent and treat a variety of bacterial infections. Synonyms: N,N'-Dibenzylethylenediamine Ampicillin Disalt; Ampicillin Benzathine; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-, compd. with N1,N2-bis(phenylmethyl)-1,2-ethanediamine (2:1); 1,2-Ethanediamine, N,N'-bis(phenylmethyl)-, bis((2S-(2α,5α,6β(S*)))-6-((aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate). Grade: ≥95%. CAS No. 33276-75-4. Molecular formula: C16H20N2.2(C16H19N3O4S). Mole weight: 939.15. | |
| Ampicillin dimer | An impurity of Ampicillin, which is a broad-spectrum antibiotic used to prevent and treat a variety of bacterial infections. Synonyms: (2R)-(2R)-2-Phenylglycyl-(2R)-2-[(2R,4S)-4-carboxy-5,5-dimethyl-2-thiazolidinyl]glycyl-N-[(2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-phenylglycinamide. CAS No. 62326-82-3. Molecular formula: C32H38N6O8S2. Mole weight: 698.81. | |
| Ampicillin EP Impurity B | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: L-Ampicillin. Grade: > 95%. CAS No. 19379-33-0. Molecular formula: C16H19N3O4S. Mole weight: 349.41. | |
| Ampicillin EP Impurity C | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: Diketopiperazines of ampicillin. Molecular formula: C16H19N3O4S. Mole weight: 349.40. | |
| Ampicillin EP Impurity D | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: penicilloic acids of ampicillin; Ampicillin Impurity D. Grade: > 95%. CAS No. 1642629-93-3. Molecular formula: C16H21N3O5S. Mole weight: 367.43. | |
| Ampicillin EP Impurity E | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: Ampicillinyl-D-phenylglycine. Grade: > 95%. CAS No. 1207726-28-0. Molecular formula: C24H26N4O5S. Mole weight: 482.56. | |
| Ampicillin EP Impurity F (2R-Isomer) | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: 4-Thiazolidinecarboxylic acid, 2-[[(aminophenylacetyl)amino]methyl]-5,5-dimethyl-, [2R-[2α(R*),4β]]-; 4-Thiazolidinecarboxylic acid, 2-[[[(2R)-aminophenylacetyl]amino]methyl]-5,5-dimethyl-, (2R,4S)-; Ampicillin EP Impurity F. Grade: > 95%. CAS No. 124774-48-7. Molecular formula: C15H21N3O3S. Mole weight: 323.41. | |
| Ampicillin EP Impurity F (2S-Isomer) | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: 4-Thiazolidinecarboxylic acid, 2-[[(aminophenylacetyl)amino]methyl]-5,5-dimethyl-, [2S-[2α(S*),4α]]-. CAS No. 124774-49-8. Molecular formula: C15H21N3O3S. Mole weight: 323.41. | |
| Ampicillin EP Impurity G | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: 3,6-Diphenylpiperazine-2,5-dione, (3R,6R)-. Grade: > 95%. CAS No. 31485-02-6. Molecular formula: C16H14N2O2. Mole weight: 266.3. | |
| Ampicillin EP Impurity H | An impurity of Ampicillin and Cefaclor. Synonyms: 3-Phenylpyrazin-2-ol; Cefaclor EP Impurity F. Grade: > 95%. CAS No. 73200-73-4. Molecular formula: C10H8N2O. Mole weight: 172.18. | |
| Ampicillin EP Impurity I | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: D-Phenylglycylampicillin. Grade: > 95%. CAS No. 10001-82-8. Molecular formula: C24H26N4O5S. Mole weight: 482.56. | |
| Ampicillin EP Impurity J | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: (2S,5R,6R)-6-[(2,2-Dimethylpropanoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. Grade: > 95%. CAS No. 6489-58-3. Molecular formula: C13H20N2O4S. Mole weight: 300.38. | |
| Ampicillin EP Impurity K | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: (2R)-2-[(2,2-Dimethylpropanoyl)amino]-2-phenylacetic acid. Grade: > 95%. CAS No. 40610-41-1. Molecular formula: C13H17NO3. Mole weight: 235.29. | |
| Ampicillin EP Impurity M | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: co-oligomers of ampicillin and of penicilloic acids of ampicillin. | |
| Ampicillin EP Impurity N | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: (3S)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-2,2-dimethyl-7-oxo-2,3,4,7-tetrahydro-1,4-thiazepine-3-carboxylic acid. Molecular formula: C16H19N3O4S. Mole weight: 349.40. | |
| Ampicillin oligomer 1 (dimer) | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Molecular formula: C32H38N6O8S2. Mole weight: 698.81. | |
| Ampicillin oligomer 1 (trimer) | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. CAS No. 114977-84-3. Molecular formula: C48H57N9O12S3. Mole weight: 1048.21. | |
| Ampicillin oligomer 2 | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Molecular formula: C32H40N6O9S2. Mole weight: 716.82. | |
| Ampicillin open ring dimer | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: (4S)-2-{1-[(R)-2-amino-2-phenylacetamido]-2-[(1R)-2-{[(4S)-4-carboxy-5,5-dimethylthiazolidin-2-yl]methylamino}-2-oxo-1-phenylethylamino]-2-oxoethyl}-5,5-dimethylthiazolidine-4-carboxylic acid. Molecular formula: C31H40N6O7S2. Mole weight: 672.82. | |
| Ampicillin sodium | Ampicillin is a beta-lactam antibiotic that is a part of the aminopenicillin family. It is mainly used for infections and sepsis of the lungs, intestines, biliary tract, urinary tract caused by sensitive bacteria. Synonyms: D-(-)-6-(2-Amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Monosodium Salt; [2S-[2α,5α,6β(S*)]]-6-[(Aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Monosodium Salt; (2S,5R,6R)-6-[[(2R)-Aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Monosodium Salt; Alpen N; Amcill S; Ampi-Dry 5000; Ampicillin Sodium; Ampicillin Sodium Salt; Ampicillin-Na; Ampicin; Anhypen; Binotal Sodium; Britapen Injection; Cilleral; D-α-Aminobenzylpenicillin Sodium Salt; Monosodium Ampicillin; Omnipen N; Pamecil; Pen A/N; Penbritin S; Pentrex; Polycillin N; Principen N; Sodium 6-(2-Amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; Benzylpenicillin Sodium; Amcill-S; Ampicillin natrium. Grade: 97%. CAS No. 69-52-3. Molecular formula: C16H18N3NaO4S. Mole weight: 371.39. | |
| Ampilloyl aminopenicillanic acid | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: (2S,5R,6R)-6-{2-[(R)-2-Amino-2-phenylacetamido]-2-[(4S)-4-carboxy-5,5-dimethylthiazolidin-2-yl]acetamido}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. Molecular formula: C24H31N5O7S2. Mole weight: 565.66. | |
| Ampiroxicam | Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug. Synonyms: CP 65703; CP65703; CP-65703. Grade: >98%. CAS No. 99464-64-9. Molecular formula: C20H21N3O7S. Mole weight: 447.46. | |
| AMPK activator | AMP-activated protein kinase (AMPK) is a central regulator of energy homeostasis, which coordinates metabolic pathways and thus balances nutrient supply with energy demand. D942 is thought to activate AMPK by inhibiting mitochondrial complex I, producing an increase in AMP levels. AMPK activator stimulates glucose uptake in L6 myocytes and promotes phosphorylation of acetyl-CoA carboxylase, which shown to enhance glucose uptake in L6 myocytes (EC50 = 11.7 μM). Reduces blood glucose levels in ZDF rats in vivo (oral dose 30-100 mg/kg). Because of the favorable physiological outcomes of AMPK activation on metabolism, AMPK has been considered to be an important therapeutic target for controlling human diseases including metabolic syndrome and cancer. Synonyms: D942; AMPK activator; 5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]furan-2-carboxylic Acid. Grade: ≥95%. CAS No. 849727-81-7. Molecular formula: C22H21FO4. Mole weight: 368.4. | |
| AMPK activator 1 | AMPK activator 1 is an AMPK activator extracted from patent WO2013116491A1 (compound No.1-75, EC50 < 0.1μM). Synonyms: 2-Benzofurancarboxamid?e, N-[1-(4-pyridinylmethyl)?-4-piperidinyl]?-5-[[1-[4-(trifluoromethyl)?phenyl]?-4-piperidinyl]?oxy]?-. CAS No. 1152423-98-7. Molecular formula: C32H33F3N4O3. Mole weight: 578.62. | |
| AMPK activator 4 | AMPK activator 4 is a potent AMPK activator without inhibition of mitochondrial complex I. AMPK activator 4 selectively activates AMPK in the muscle tissues. Anti-hyperglycemic effect. Synonyms: AMPK activator 4; 2493239-46-4; CHEMBL4798218; MS-27389; HY-131334; CS-0133422; 2-(4-chlorophenoxy)-N-[4-[(4-cyanophenyl)methoxy]phenyl]-2-methylpropanamide. Grade: 99%. CAS No. 2493239-46-4. Molecular formula: C24H21ClN2O3. Mole weight: 420.89. | |
| Ampkinone | Ampkinone, an AMPK activitor, has been found to have potential effect in the treatment of diabete and obesity. IC50: 4.3 uM(EC50). Uses: Ampkinone is an ampk activitor that has been found to have potential effect in the treatment of diabete and obesity. Synonyms: 2-(4-Benzoylphenyl)-6-hydroxy-7-methoxy-4,4-dimethyl-[1]Benzopyrano[3,4-e]isoindole-1,3(2H,4H)-dione. Grade: 98%. CAS No. 1233082-79-5. Molecular formula: C31H23NO6. Mole weight: 505.52. | |
| AMP-PCP | AMP-PCP is an ATP analogue and can bind to the N-terminal domain of Hsp90 with a Kd of 3.8 μM. AMP-PCP binding is beneficial to the formation of Hsp90 active homodimer. Synonyms: Phosphomethylphosphonic acid adenylate ester; L-betagamma-meATP; beta,gamma-Methylene ATP; 5'-O-(Hydroxy{[hydroxy(phosphonomethyl)phosphoryl]oxy}phosphoryl)adenosine; 5'-adenylic acid, monohydride with methylenebis(phosphonic acid); 5'-adenylyl (β,γ-methylene)diphosphonate; 9H-Purin-6-amine, 9-[5-O-[hydroxy[[hydroxy(phosphonomethyl)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-. Grade: ≥95%. CAS No. 3469-78-1. Molecular formula: C11H18N5O12P3. Mole weight: 505.21. | |
| AMP PNP | AMP PNP is an analogue of AMP and has been found to be a Kir6 (KATP) channel blocker. Synonyms: Adenosine-5'-[(β,γ)-imido]triphosphate tetralithium salt. Grade: ≥90% by HPLC. CAS No. 72957-42-7. Molecular formula: C10H13Li4N6O12P3. Mole weight: 529.93. | |
| Amprenavir | Amprenavir promotes the specific interactions between the nuclear receptor pregnane X receptor (PXR) and the coactivators SRC-1 and PBP. Uses: Amprenavir is indicated in combination with other antiretroviral agents in the treatment of hiv-1 infection. Synonyms: VX-478; VX 478; VX478; Amprenavir; Agenerase; Prozei. Grade: >98%. CAS No. 161814-49-9. Molecular formula: C25H35N3O6S. Mole weight: 505.63. | |
| Amprolium | Amprolium, a thiamine derivative, could be commonly useful in poultry as a coccidiostat. Uses: Amprolium could be commonly useful in poultry as a coccidiostat. Synonyms: Amprolium; Amprolio; Amprolium[ban:inn]; Amprolium [INN-Latin]; Amprolio [INN-Spanish]. Grade: 98%. CAS No. 121-25-5. Molecular formula: C14H19ClN4. Mole weight: 278.78. | |
| Amredobresib | Amredobresib is a potent BET inhibitor that inhibits the binding of brominated domains to acetylated lysine on histones H3 and H4, and is therefore an important regulator of gene transcription. It is used in acute myeloid leukemia (AML) and cancer research. (Extracted from patent WO2019145410A1 and WO2021175824A1). Synonyms: 1,2,4-Triazolo(4,3-a)pyrazin-8-amine, N,3-dimethyl-6-(6-(4-methyl-1-piperazinyl)-1-(phenylmethyl)-1hbenzimidazol-2-yl)-; 6-(1-Benzyl-6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl)-N,3-dimethyl-(1,2,4)triazolo(4,3-a)pyrazin-8-amine; 6-[1-Benzyl-6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-N,3-dimethyl[1,2,4]triazolo[4,3-a]pyrazin-8-amine. CAS No. 1610044-98-8. Molecular formula: C26H29N9. Mole weight: 467.57. | |
| AMRI-59 | AMRI-59 is a potent inhibitor of PrxI with anti-tumor activity. Synonyms: 4-(4-(1H-pyrrol-1-yl)benzyl)-N-(3-acetylphenyl)piperidine-1-carboxamide. CAS No. 923515-92-8. Molecular formula: C25H27N3O2. Mole weight: 401.50. | |
| Amrinone | Amrinone is a selective cAMP phosphodiesterase (PDE-3) inhibitor with positive inotropic and vasodilatory activity. It is a simple, non-glycoside cardiotonic agent. It provides protection against ischemia-reperfusion injury in kidney, liver, and heart. It has the ability to stimulate calcium ion influx into the cardiac cell. It is used in the treatment of congestive heart failure. It increases cardiac contractility as a vasodilator. It acts by inhibiting the breakdown of both cAMP and cGMP by the phosphodiesterase (PDE3) enzyme. It is a drug that may improve the prognosis in patients with congestive heart failure. It has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). It was developed by Sanofi and has been listed. Uses: Amrinone is a simple, non-glycoside cardiotonic agent. it provides protection against ischemia-reperfusion injury in kidney, liver, and heart. it is used in the treatment of congestive heart failure. it increases cardiac contractility as a vasodilator. Synonyms: Inamrinone; Wincoram; Inocor; Cordemcura; Win-40680; Win40680; 3-Amino-5-pyridin-4-yl-1H-pyridin-2-one. Grade: 98%. CAS No. 60719-84-8. Molecular formula: C10H9N3O. Mole weight: 187.20. | |
| Amrioclomol | Amrioclomol is a drug candidate that amplifies the production of heat shock proteins (HSPs). Synonyms: (2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol; arimoclomol. Grade: 95%. CAS No. 289893-25-0. Molecular formula: C14H20ClN3O3. Mole weight: 313.78. | |
| Amrubicin-13C3 | Amrubicin is a synthetic anthracycline antibiotic that inhibits DNA topoisomerase II. Antineoplastic. Synonyms: (7S,9S)-9-Acetyl-9-amino-7-[(2-deoxy-β-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione-13C3. Molecular formula: C22[13C]3H25NO9. Mole weight: 486.45. | |
| Amrubicin hydrochloride | Amrubicin hydrochloride is a topoisomerase II inhibitor used in the treatment of lung cancer. Uses: Antineoplastic agents. Synonyms: Amrubicin HCl; SM-5887; Calsed; 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-9-acetyl-9-amino-7-((2-deoxy-beta-D-erythro-pentopyranosyl)oxy)-6,11-dihydroxy-, hydrochloride, (7S-cis)-; 5,12-Naphthacenedione, 9-acetyl-7-((2-deoxy-beta-D-erythro-pentopyranosyl)oxy)-7,8,9,10-tetrahydro-6,11-dihydroxy-, hydrochloride, (7S,9S)-. Grade: >98%. CAS No. 110311-30-3. Molecular formula: C25H26ClNO9. Mole weight: 519.93. | |
| Amrubicinol-13C3 (Mixture of Diastereomers) | A labelled metabolite of Amrubicin, which is active and possesses cytotoxicity 10 to 100 times that of the parent drug. Synonyms: (7S,9S)-9-Amino-7-[(2-deoxy-β-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-9-(1-hydroxyethyl)-5,12-naphthacenedione-13C3; 13-Hydroxy SM 5887-13C3. Molecular formula: C22[13C]3H27NO9. Mole weight: 488.46. | |
| Amrubicinol (Mixture of Diastereomers) | A metabolite of Amrubicin, which is active and possesses a cytotoxicity 10 to 100 times that of the parent drug. Uses: A metabolite of amrubicin, which is active and possesses a cytotoxicity 10 to 100 times that of the parent drug. Synonyms: (7S,9S)-9-Amino-7-[(2-deoxy-β-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-9-(1-hydroxyethyl)-5,12-naphthacenedione; 13-Hydroxy SM 5887. CAS No. 186353-53-7. Molecular formula: C25H27NO9. Mole weight: 485.48. | |
| Amsacrine | Amsacrine is an antineoplastic agent which can intercalate into the DNA of tumor cells. It also expresses topoisomerase inhibitor activity, specifically inhibiting topoisomerase II. Synonyms: AMSA; m-AMSA; CI 880, CI880, CI-880; SN-11841; SN 11841; SN11841; acridinyl anisidide. Grade: >98%. CAS No. 51264-14-3. Molecular formula: C21H19N3O3S. Mole weight: 393.46. | |
| Amsacrine hydrochloride | Amsacrine hydrochloride is an antineoplastic agent which can intercalate into the DNA of tumor cells. It also expresses topoisomerase inhibitor activity, specifically inhibiting topoisomerase II. Uses: Antineoplastic agents. Synonyms: AMSA hydrochloride; m-AMSA hydrochloride; CI-880 hydrochloride; SN-11841 hydrochloride; CI 880 hydrochloride; SN 11841 hydrochloride; CI880 hydrochloride; SN11841 hydrochloride; acridinyl anisidide hydrochloride. Grade: >98%. CAS No. 54301-15-4. Molecular formula: C21H20ClN3O3S. Mole weight: 429.92. | |
| Amsalog | Asulacrine isethionate is the isethionate salt of an amsacrine analogue with antineoplastic properties. Asulacrine inhibits the enzyme topoisomerase ll, thereby blocking DNA replication and RNA and protein synthesis. Synonyms: Asulacrine isethionate; CI-921. CAS No. 80841-48-1. Molecular formula: C26H30N4O8S2. Mole weight: 590.67. | |
| amsilarotene | Amsilarotene (TAC-101) is a retinobenzoic acid with potential antineoplastic activity. TAC-101 inhibits retinoblastoma-gene product (RB) phosphorylation and increases the presence of 2 cyclin-dependent kinase (CDK) inhibitors, resulting in cell cycle arrest. Synonyms: TAC-101; TAC 101; TAC101; Am 555S; Benzoic acid, 4-[[3,5-bis(trimethylsilyl)benzoyl]amino]-. Grade: 99%. CAS No. 125973-56-0. Molecular formula: C20H27NO3Si2. Mole weight: 385.61. | |
| AMTB hydrochloride | The hydrochloride salt form of AMTB, which has been found to be a TRPM8 channel blocker. Synonyms: N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamide hydrochloride. Grade: ≥99% by HPLC. CAS No. 926023-82-7. Molecular formula: C23H26N2O2S.HCl. Mole weight: 430.99. | |
| Amthamine dihydrobromide | Amthamine dihydrobromide is the dihydrobromide salt of amthamine, which is a highly selective histamine H2 receptor agonist. It is a weak antagonist at H3 and has no activity at H1 receptors. It decreases myogenic tone and induces vasodilation of cerebral arteries in vitro. It can be used in the suppression of the release of serotonin and H2 receptor-mediated eosinophil peroxidase (EPO). It has been used to study the effect of mast cells on T regulatory cell function. Synonyms: 5-(2-Aminoethyl)-4-methylthiazol-2-amine Dihydrobromide; A 4730 Dihydrobromide; 2-Amino-4-methyl-5-thiazoleethanamine dihydrobromide; 2-Amino-5-(2-aminoethyl)-4-methylthiazole dihydrobromide. Grade: ≥99% by HPLC. CAS No. 142457-00-9. Molecular formula: C6H13N3SBr2. Mole weight: 319.06. | |
| AMT hydrochloride | The hydrochloride salt form of AMT, which has been found to be a reversible inhibitor of iNOS and could probably be useful in treatment of inflammatory and autoimmune disorders. Synonyms: 2-Amino-5,6-dihydro-6-methyl-4H-1,3-thiazine hydrochloride. Grade: ≥95% by HPLC. CAS No. 21463-31-0. Molecular formula: C5H10N2S.HCl. Mole weight: 166.67. | |
| AM-TS23 | AM-TS23 has been found to be a DNA polymerase λ and β inhibitor and could be effective in studies of colorectal cancer. Synonyms: AM-TS23; AM TS23; AMTS23; (5Z)-5-[[(4-[(2-Methylphenyl)thio]-3-nitrophenyl]methylene]-2-thioxo-4-thiazolidinone. Grade: ≥98% by HPLC. CAS No. 1489285-17-7. Molecular formula: C17H12N2O3S3. Mole weight: 388.48. | |
| Amustaline dihydrochloride | Amustaline dihydrochloride is a nucleic acid targeted alkylator that is an effective pathogen inactivation agent for blood components containing red blood cells. It has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products). Synonyms: S-303 dihydrochloride; 2-[Bis(2-chloroethyl)amino]ethyl N-9-acridinyl-β-alaninate dihydrochloride; β-Alanine, N-9-acridinyl-, 2-[bis(2-chloroethyl)amino]ethyl ester, hydrochloride (1:2). Grade: ≥97%. CAS No. 210584-54-6. Molecular formula: C22H27Cl4N3O2. Mole weight: 507.28. | |
| Amuvatinib | Amuvatinib, also known as MP-470, is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity. MP470 inhibits activities of other receptor tyrosine kinases. This agent also suppresses the induction of DNA repair protein Rad51, thereby potentiating the activities of DNA damage-inducing agents. Synonyms: HPK 56; HPK-56; HPK56; MP-470; MP470; MP 470. Grade: 0.98. CAS No. 850879-09-3. Molecular formula: C23H21N5O3S. Mole weight: 447.513. | |
| AMXT-1501 tetrahydrochloride | AMXT-1501 tetrahydrochloride is an orally active inhibitor of polyamine transport. It blocks tumor growth in immunocompetent mice but not in athymic nude mice lacking T cells. Grade: ≥98%. Molecular formula: C32H72Cl4N6O2. Mole weight: 714.77. | |
| AMY-101 acetate | AMY-101 acetate inhibits naturally occurring periodontitis in non-human primates (NHPs). AMY-101 acetate exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation. Synonyms: Cp40 acetate. Grade: 99%. Molecular formula: C85H121N23O20S2. Mole weight: 1849.16. | |
| AMY-101 TFA | C3 Complement Inhibitor AMY-101 is a compstatin-based inhibitor of human complement component C3. AMY-101 TFA exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation. Synonyms: H-D-Tyr-Ile-Cys(1)-Val-Trp(Me)-Gln-Cp40 TFA; Asp-Trp-Sar-Ala-His-Arg-Cys(1)-N(Me)Ile-NH2.TFA. Grade: 98%. CAS No. 1789738-04-0. Molecular formula: C83H117N23O18S2.xC2HF3O2. | |
| Amycolatopsin A | Amycolatopsin A is a macrolide polyketide found in Amycolatopsis that has antimycobacterial and anticancer activities. It is active against M. bovis and M. tuberculosis (IC50s = 0.4 and 4.4 μM, respectively) but not B. subtilis, S. aureus, E. coli, or P. aeruginosa (IC50s = >30 μM for all). Amycolatopsin A is also cytotoxic to SW620 colorectal and NCI H460 lung cancer cells (IC50s = 0.08 and 1.2 μM, respectively). Grade: ≥95%. CAS No. 2209112-96-7. Molecular formula: C60H98O23. Mole weight: 1187.40. | |
| Amycolatopsin B | Amycolatopsin B is a bacterial metabolite produced by Amycolatopsis that has anticancer activity. It is cytotoxic to NCI H460 lung and SW620 colon cancer cells (IC50s = 0.28 and 0.14 μM, respectively). Grade: >95%. CAS No. 2209112-97-8. Molecular formula: C60H98O22. Mole weight: 1171.40. | |
| Amycolatopsin C | Amycolatopsin C is a polyketide macrolide that has been found in Amycolatopsis and has antimycobacterial and anticancer activities. It is active against M. bovis and M. tuberculosis (IC50s = 2.7 and 5.7 μM, respectively). Amycolatopsin C is also cytotoxic to SW620 colorectal and NCI H460 lung cancer cells (IC50s = 10 and 5.9 μM, respectively). Grade: ≥95%. Molecular formula: C47H76O17. Mole weight: 913.09. | |
| Amyl 2-acetamido-2-deoxy-b-D-glucopyranoside | Amyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a versatile biomedical compound, finding applications in the research of an array of ailments. Identified as N-acetylmuramic acid, this compound showcases notable antibacterial attributes, rendering it invaluable in the enzymatic assessment of bacterial muramidases. Crucially, it assumes an indispensable role in peptidoglycan research and development, a pivotal constituent of bacterial cell walls. Synonyms: N-((2R,3R,4R,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-(pentyloxy)tetrahydro-2H-pyran-3-yl)acetamide. CAS No. 94483-64-4. Molecular formula: C13H25NO6. Mole weight: 291.34. | |
| Amyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside | Amyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is an extensively employed compound in the realm of biomedicine, manifesting as an invaluable asset for the scrutiny of glycosylation mechanisms and the pioneering of groundbreaking pharmaceuticals. Synonyms: beta-D-Glucopyranoside, pentyl 2-(acetylamino)-2-deoxy-, 3,4,6-triacetate. CAS No. 146288-30-4. Molecular formula: C19H31NO9. Mole weight: 417.45. | |
| Amylin | It is a polypeptide sequence containing 37 amino acids. Synonyms: Diabetes-associated peptide; IAPP; IAPP protein; Insulinoma amyloid peptide; Insulinoma amyloid polypeptide; Islet amyloid polypeptide; Protein IAPP; Proteins, IAPP. Grade: 95%. CAS No. 106602-62-4. Molecular formula: C165H261N51O55S2. Mole weight: 3903.3. | |
| Amylin (human) (amidated) trifluoroacetate salt | Amylin is a pancreatic β-cell hormone that produces effects in several different organ systems. Amylin is a 37-amino-acid peptide that activates its specific receptors, which are multisubunit G protein and resulting in multiple receptor subtypes. Amylin's major role is as a glucoregulatory hormone, and it is an important regulator of energy metabolism in health and disease. Amidated amylin increases the rate of glycogen synthesis induced by insulin in isolated rat soleus muscle when used at a concentration of 1 nM, while linear non-amidated amylin has no effect. Synonyms: IAPP (human) (amidated); Islet Amyloid Polypeptide (human) (amidated). Grade: ≥95%. Molecular formula: C165H261N51O55S2·xCF3COOH. Mole weight: 3903.28. | |
| Amylin (human) trifluoroacetate salt | Amylin is a pancreatic β-cell hormone that produces effects in several different organ systems. Amylin is a 37-amino-acid peptide that activates its specific receptors, which are multisubunit G protein and resulting in multiple receptor subtypes. Amylin's major role is as a glucoregulatory hormone, and it is an important regulator of energy metabolism in health and disease. Amidated amylin increases the rate of glycogen synthesis induced by insulin in isolated rat soleus muscle when used at a concentration of 1 nM, while linear non-amidated amylin has no effect. Synonyms: IAPP (human); Islet Amyloid Polypeptide (human). Grade: ≥95%. Molecular formula: C165H260N50O56S2·xCF3COOH. Mole weight: 3904.27. | |
| Amylin (rat, mouse) trifluoroacetate salt | Amylin is a pancreatic β-cell hormone that produces effects in several different organ systems. Amylin is a 37-amino-acid peptide that activates its specific receptors, which are multisubunit G protein and resulting in multiple receptor subtypes. Amylin's major role is as a glucoregulatory hormone, and it is an important regulator of energy metabolism in health and disease. Amidated amylin increases the rate of glycogen synthesis induced by insulin in isolated rat soleus muscle when used at a concentration of 1 nM, while linear non-amidated amylin has no effect. Synonyms: IAPP (rat, mouse); Islet Amyloid Polypeptide (rat, mouse). Grade: ≥95%. Molecular formula: C167H272N52O53S2·xCF3COOH. Mole weight: 3920.40. | |
| amyloid P-IN-1 | Amyloid P-IN-1 is an orally available small molecule inhibitor of serum amyloid P component (SAP) binding to amyloid fibrils for the depletion of serum amyloid-P (SAP) component from the circulation. Synonyms: GSK-3039294; GSK 3039294. Grade: 99%. CAS No. 1819986-22-5. Molecular formula: C30H44N2O14. Mole weight: 656.68. | |
| Amylopectin - from maize | Amylopectin - from maize boasts its status as a paramount and environmentally sustainable byproduct obtained from maize starch. This versatile substance has been pervasively employed within the field of biomedical research due to its inherent biocompatibility and degradability. Serving as a formidable carrier for drug delivery systems and tissue engineering, its intricate composition exudes proficiency in encapsulating an array of pharmaceuticals, thus promoting precise release and optimized therapeutic effects. Synonyms: Amaizo 839; Amioca; Amioca Powder T; Amioca TF; Amioca WCS; Amylopectins; Farinex WM 55; Honen Alpha Waxy Starch; Kosol; Matsunorin A; Matsunorin N; Novation 5600; Pectin, amylo; Starch, waxy; Ultraamylopectin N; Ultrasperse A; Versasheen; Waxilys; Waxy Alpha Y; Waxy corn starch; Waxy Corn Starch Y; Waxy maize starch; Waxy potato starch; Waxy starch; Waxy Starch Y; WCS. CAS No. 9037-22-3. Molecular formula: (C6H10O5)n. | |
| Amylose | Amylose is a linear glucose polymer widely used in the biomedical industry utilized in the development of compound delivery systems, particularly for controlled release of compounds targeting various diseases. Synonyms: Amylose EX 1; AO 512; AS 10; AS 30 (carbohydrate); AS 70; Kleptose Linecaps 17; Polyamylose; Sigma AO 512; V Amylose; α-Amylose. CAS No. 9005-82-7. Molecular formula: (C6H10O5)n. | |
| Amylose azure | Amylose azure is a derivative of amylose, a polysaccharide composed of glucose units. It is often used in biochemical assays to study enzyme activity, particularly for amylases, which break down starch. It is used as a substrate to detect and measure the activity of amylase enzymes. Synonyms: Remazol brilliant blue carboxymethyl amylose; Alphachrome. CAS No. 71501-06-9. | |
| Amylostatin XG 1-Thiophenyl Nonaacetate | Amylostatin XG 1-Thiophenyl Nonaacetate is a protected intermediate of Amylostatin XG, an analogue of an α-glucosidase inhibitor, Acarbose. Molecular formula: C43H55NO21S. Mole weight: 953.96. | |
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