BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 6-Methoxy-2-naphthoic acid | A metabolite of Naproxen, which is a non-selective COX inhibitor. Synonyms: 6-methoxynaphthalene-2-carboxylic acid. Grades: 97 %. CAS No. 2471-70-7. Molecular formula: C12H10O3. Mole weight: 202.21. |  |
| 6-Methoxy-2-naphthol | A metabolite of Naproxen, which is a non-selective COX inhibitor. Synonyms: 2-Naphthalenol, 6-methoxy-; 2-Naphthol, 6-methoxy-; 6-Methoxy-2-naphthalenol; 2-Hydroxy-6-methoxynaphthalene; 2-Methoxy-6-naphthol; 6-Methoxy-2-hydroxynaphthalene; 6-Methoxy-β-naphthol; NSC 149908; Naproxen Impurity H. Grades: ≥95%. CAS No. 5111-66-0. Molecular formula: C11H10O2. Mole weight: 174.20. | |
| 6-Methoxynaphthalene-2-acetic Acid | A metabolite of Naproxen, which is a non-selective COX inhibitor. Synonyms: 2-(6-methoxy-2-naphthalenyl)acetic acid; 2-(6-methoxynaphthalen-2-yl)acetic acid. Grades: 97 %. CAS No. 23981-47-7. Molecular formula: C13H12O3. Mole weight: 216.23. | |
| 6-Oxo-(S,S)-Palonosetron | 6-Oxo-(S,S)-Palonosetron is an impurity of Palonosetron, which is a potent, single stereoisomeric 5-HT3 receptor antagonist developed to prevent chemotherapy-induced nausea and vomiting. Synonyms: 6-Oxo-(S,S)-Palonosetron (~90%); (S)-2-((S)-Quinuclidin-3-yl)-3,3a,4,5-tetrahydro-1H-benzo[de]isoquinoline-1,6(2H)-dione. Grades: 90%. CAS No. 848074-10-2. Molecular formula: C19H22N2O2. Mole weight: 310.39. | |
| (6S)-Hydroxy (S,S)-Palonosetron | An impurity of Palonosetron which is used for preventing nausea and vomiting caused by cancer chemotherapy. Synonyms: (3aS,6S)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-6-hydroxy-1H-benz[de]isoquinolin-1-one. Grades: > 95%. CAS No. 848074-08-8. Molecular formula: C19H24N2O2. Mole weight: 312.42. | |
| 7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene | An impurity of Raloxifene. Raloxifene is selective estrogen receptor modulator. It can be used in the prevention of osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast. Synonyms: 6-Hydroxy-2-(4-hydroxyphenyl)-7-[4-(2-piperidin-1-yl-ethoxy)benzoyl]-benzo[b]thien-3-yl]-[4-[2-(1-piperidinyl)ethoxy]phenyl]methanone; Raloxifene Impurity I. Grades: > 95%. CAS No. 1159977-58-8. Molecular formula: C42H44N2O6S. Mole weight: 704.89. | |
| 7,7'-Nonane-1,9-diylbis[estra-1,3,5(10)-triene-3,17β-diol] Tetraacetate | 7,7'-Nonane-1,9-diylbis[estra-1,3,5(10)-triene-3,17β-diol] Tetraacetate is an impurity of Fulvestrant, which is a drug for breast cancer. Synonyms: Fulvestrant Impurity D Tetraacetate. Molecular formula: C53H72O8. Mole weight: 837.13. | |
| 7,8-Dihydro Naphthol | 7,8-Dihydro-1-naphthalenol can be used as reagent/reactant in stereoselective preparation of indanes via chiral hypervalent iodine - mediated ring contraction of dihydronaphthalenes. Synonyms: 7,8-Dihydro-1-naphthol; 8-Hydroxy-1,2-dihydronaphthalene. Grades: > 95%. CAS No. 51927-48-1. Molecular formula: C10H10O. Mole weight: 146.19. | |
| 7,8-Dihydropteroate | Synonyms: Dihydropteroate; Dihydropteroic acid; 7,8-Dihydropteroic acid; Dihydropterate; 4-[(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)methylamino]benzoic acid. CAS No. 2134-76-1. Molecular formula: C14H14N6O3. Mole weight: 314.305. | |
| 7-alpha-Thiomethyl Spironolactone | A metabolite of Spironolactone. Synonyms: 17a-Hydroxy-7a-(methylthio)-3-oxo-pregn-4-ene-21-carboxylic Acid g-Lactone. Grades: > 95%. CAS No. 38753-77-4. Molecular formula: C23H32O3S. Mole weight: 388.57. | |
| 7-Aminocephalosporanic acid | It is the starting material for the semisynthesis of cephalosporin and can be prepared by mild acid hydrolysis or enzymatic hydrolysis of cephalosporin C. Synonyms: 7-ACA. Grades: >98%. CAS No. 957-68-6. Molecular formula: C10H12N2O5S. Mole weight: 272.28. | |
| 7-Beta-Spironolactone | the 7β-isomer of Spironolactone. Synonyms: (7β,17α)-7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic Acid γ-Lactone; 17-Hydroxy-7β-mercapto-3-oxo-17α-pregn-4-ene-21-carboxylic Acid γ-Lactone Acetate; 3'-(3-Oxo-7β-acetylthio-17β-hydroxyandrost-4-en-17α-yl)-propionic Acid Lactone; 7β-(Acetyl. Grades: > 95%. CAS No. 33784-05-3. Molecular formula: C24H32O4S. Mole weight: 416.58. | |
| 7-Epi-lincomycin 2,7-Dipalmitate | 7-Epi-lincomycin 2,7-Dipalmitate is a Lincomycin 2-diester, similar to Lincomycin 2-Palmitate, the monoester, which shows highly active anti-bacterial properties. Grades: > 95%. Molecular formula: C50H94N2O8S. Mole weight: 883.35. | |
| 7-Ethylmethylamino Analogue | Grades: > 95%. Molecular formula: C24H29N3O7. Mole weight: 471.51. | |
| 7-Hydroxy Granisetron | Synonyms: 7-Hydroxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide. Grades: > 95%. CAS No. 133841-15-3. Molecular formula: C18H24N4O2. Mole weight: 328.42. | |
| 7-Hydroxy Loxapine | 7-Hydroxy Loxapine is a metabolite of Loxapine, a neuroleptic medication used to treat patients with schizophrenia and obsessive compulsive disorder. Synonyms: 2-Chloro-11-(4-methyl-1-piperazinyl)-dibenz[b,f][1,4]oxazepin-7-ol; 2-Chloro-7-hydroxy-11-(4-methyl-1-piperazinyl)dibenz[b, f][1, 4]oxazepine; 2-Chloro-7-hydroxy-11-(4-methyl-1-piperazinyl)dibenz[b,f]oxazepine. Grades: > 95%. CAS No. 37081-75-7. Molecular formula: C18H18ClN3O2. Mole weight: 343.81. | |
| 7-Hydroxy-loxapine-glucuronide | 7-Hydroxy-loxapine-glucuronide is a metabolite of Loxapine, a dibenzoxazepine antipsychotic agent. Synonyms: (2S,3S,4S,5R,6S)-6-((2-Chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepin-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid. Grades: > 95%. Molecular formula: C24H26ClN3O8. Mole weight: 519.93. | |
| 7-Hydroxy Loxapine N-Oxide | 7-Hydroxy Loxapine N-Oxide is a metabolite of Loxapine, a dibenzoxazepine antipsychotic agent. Synonyms: 2-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-dibenz[b,f][1,4]oxazepin-7-ol; 2-Chloro-11-(4-methyl-1-piperazinyl)-dibenz[b,f][1,4]oxazepin-7-ol N-Oxide. Grades: > 95%. CAS No. 37081-77-9. Molecular formula: C18H18ClN3O3. Mole weight: 359.81. | |
| 7-Hydroxy-loxapine-sulfate Sodium Salt | 7-Hydroxy-loxapine-sulfate Sodium Salt is a metabolite of Loxapine, a dibenzoxazepine antipsychotic agent. Grades: > 95%. Molecular formula: C18H17ClN3O5SNa. Mole weight: 445.85. | |
| 7-Hydroxy Methotrexate | 7-Hydroxy Methotrexate is a metabolite of Methotrexate, which is used as a antineoplastic and antirheumatic. Uses: Folic acid antagonists. Synonyms: 7-Hydroxy Amethopterin, 4-Amino-7-hydroxy-10-methylpteroylglutamic Acid; N-[4-[[ (2, 4-Diamino-7, 8-dihydro-7-oxo-6-pteridinyl) methyl]methylamino]benzoyl]-L-glutamic Acid; NSC 380962. Grades: > 95%. CAS No. 5939-37-7. Molecular formula: C20H22N8O6. Mole weight: 470.44. | |
| 7-Hydroxy Methotrexate Trisodium Salt | 7-Hydroxy Methotrexate Trisodium Salt is one of methotrexate impurities. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Molecular formula: C20H19N8O6.3Na. Mole weight: 536.38. | |
| 7-Hydroxy N-Desalkyl Quetiapine | A metabolite of Quetiapine. Quetiapine is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. Grades: > 95%. CAS No. 232597-73-8. Molecular formula: C17H17N3OS. Mole weight: 311.41. | |
| 7-Hydroxy Ondansetron | An impurity of Ondansetron, which is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. Synonyms: 1,2,3,9-Tetrahydro-7-hydroxy-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]- 4H-carbazol-4-one. Grades: > 95%. CAS No. 126702-17-8. Molecular formula: C19H20N2O2. Mole weight: 311.39. | |
| 7-Hydroxy Quetiapine Hemifumarate | A metabolite of Quetiapine. Quetiapine is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. Grades: > 95%. Molecular formula: C21H25N3O3S. 0.5 C4H4O4. Mole weight: 457.56. | |
| 7-Hydroxy Ropinirole HBr | An impurity of Ropinirole.Ropinirole acts as a D2, D3, and D4 dopamine receptor agonist with highest affinity for D2. It is weakly active at the 5-HT2, and α2 receptors and is said to have virtually no affinity for the 5-HT1, GABA, mAChRs, α1, and β-adrenoreceptors. Grades: > 95%. CAS No. 81654-57-1. Molecular formula: C16H24N2O2. HBr. Mole weight: 357.29. | |
| 7-Methoxy-2-methylisoquinoline-1,3(2H,4H)-dione | 7-Methoxy-2-methylisoquinoline-1,3(2H,4H)-dione is an impurity of Gliquidone, which is an ATP-sensitive K+ channel antagonist. Synonyms: 1,3(2H,4H)-Isoquinolinedione, 7-methoxy-2-methyl-; 7-Methoxy-2-methyl-1,3(2H,4H)-isoquinolinedione; 4-Methoxy-N-methylhomophthalimide. Grades: ≥95%. CAS No. 76746-95-7. Molecular formula: C11H11NO3. Mole weight: 205.21. | |
| 7-METHYLGUANOSINE 5'-DIPHOSPHATE [TEA Salt] | Cas No. 104809-16-7. | |
| 7-Methyl Memantine Hydrochloride | 7-Methyl Memantine is an impurity of Memantine (HCl salt) which is used as an antiparkinsonian and antispasmodic. Synonyms: 3,5,7-Trimethyl-tricyclo[3.3.1.13,7]decan-1-amine Hydrochloride; 3,5,7-Trimethyl-1-adamantanamine Hydrochloride; 3,5,7-Trimethyl-tricyclo[3.3.1.13,7]decan-1-amine Hydrochloride. Grades: > 95%. CAS No. 15210-60-3. Molecular formula: C13H24ClN. Mole weight: 229.79. | |
| 7-(N-Benzyloxycarbonylglycyl-glycyl-leucyl)amino-4-methylcoumarin | 7-(N-Benzyloxycarbonylglycyl-glycyl-leucyl)amino-4-methylcoumarin is a fluorogenic substrate for the chymotrypsin-like activity of the 20S proteasome. Synonyms: 7-Z-Gly-gly-leu-ME; L-Leucinamide, N-[ (phenylmethoxy)carbonyl]glycylglycyl-N- (4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; Z-GGL-AMC. Grades: ≥98%. CAS No. 97792-39-7. Molecular formula: C28H32N4O7. Mole weight: 536.58. | |
| 8-epi Limaprost | an impurity of Limaprost. Grades: > 95%. Molecular formula: C22H36O5. Mole weight: 380.53. | |
| 8-epi-Misoprostol | Grades: > 95%. Molecular formula: C22H38O5. Mole weight: 382.55. | |
| 8-Gingerdione | Synonyms: (8)-Gingerdione; 8-Gingerdione; [8]-Gingerdione; 77334-06-6; UNII-70E1Y63Q2L; 70E1Y63Q2L; 3,5-Dodecanedione, 1-(4-hydroxy-3-methoxyphenyl)-; 1-(4-Hydroxy-3-methoxyphenyl)dodecane-3,5-dione; 4-Dodecen-3-one, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (4Z)-; CHEBI:175095; QDSRAFNZQKMHPZ-UHFFFAOYSA-N; DTXSID801316888; 3-(octadecylcarbamoyl)-2-sulfo-propanoic Acid; 8-GINGERDIONE: N=6 (CONSTITUENT OF GINGER); Q27265857; 1-(4-Hydroxy-3-methoxyphenyl)-3,5-dodecanedione, 9CI; 8-GINGERDIONE : N=6 (CONSTITUENT OF GINGER) [DSC]; 1339934-25-6. Grades: > 95%. CAS No. 77334-06-6. Molecular formula: C19H28O4. Mole weight: 320.43. | |
| 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) | 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2; L-Histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-L-argininamide; 7-36-Glucagon-like peptide 1 (Octodon degus), 8-glycine-36-L-argininamide-; Albiglutide; [Gly8,Arg36]-GLP 1 (7-36) amide (Octodon degus). Grades: ≥95%. CAS No. 224638-84-0. Molecular formula: C148H224N40O45. Mole weight: 3283.61. | |
| 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) TFA | 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) TFA is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2.TFA; L-Histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-L-argininamide trifluoroacetic acid; 7-36-Glucagon-like peptide 1 (Octodon degus), 8-glycine-36-L-argininamide-, trifluoroacetate; Albiglutide TFA; [Gly8,Arg36]-GLP 1 (7-36) amide (Octodon degus) TFA. Grades: ≥95%. Molecular formula: C150H225F3N40O47. Mole weight: 3397.63. | |
| 8-Hydroxy Loxapine | 8-Hydroxy Loxapine is the inactive metabolite of Loxapine. Synonyms: 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepin-8-ol. Grades: > 95%. CAS No. 61443-77-4. Molecular formula: C18H18ClN3O2. Mole weight: 343.81. | |
| 8-Hydroxy-loxapine-glucuronide | 8-Hydroxy-loxapine-glucuronide is a metabolite of Loxapine, a dibenzoxazepine antipsychotic agent. Synonyms: (2S,3S,4S,5R,6S)-6-((2-Chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepin-8-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid. Grades: > 95%. Molecular formula: C24H26ClN3O8. Mole weight: 519.93. | |
| 8-Hydroxy Loxapine N-Oxide | 8-Hydroxy Loxapine N-Oxide is a metabolite of Loxapine, a dibenzoxazepine antipsychotic agent. Synonyms: 2-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-dibenz[b,f][1,4]oxazepin-8-ol; 2-Chloro-11-(4-methyl-1-piperazinyl)-dibenz[b,f][1,4]oxazepin-8-ol N-Oxide. Grades: > 95%. Molecular formula: C18H18ClN3O3. Mole weight: 359.81. | |
| 8-Hydroxy-loxapine-sulfate Sodium Salt | 8-Hydroxy-loxapine-sulfate Sodium Salt is a metabolite of Loxapine, a dibenzoxazepine antipsychotic agent. Grades: > 95%. Molecular formula: C18H17ClN3O5SNa. Mole weight: 445.85. | |
| 8-Hydroxy Mianserin | 8-Hydroxy Mianserin is a metabolite of Mianserin. Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methyl-dibenzo[c,f]pyrazino[1,2-a]azepin-8-ol; 8-Hydroxymianserin. Grades: > 95%. CAS No. 57257-81-5. Molecular formula: C18H20N2O. Mole weight: 280.36. | |
| 8-Hydroxy Ondansetron | An impurity of Ondansetron, which is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. Synonyms: 1,2,3,9-Tetrahydro-8-hydroxy-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one. Grades: > 95%. CAS No. 126671-71-4. Molecular formula: C19H20N2O2. Mole weight: 311.39. | |
| 8-iso Misoprostol | 8-iso Misoprostol is a very widely sold analog of prostaglandin E1, which is potent but acts as a non-selective agonist towards the prostanoid EP receptor subgroup. Synonyms: 9-oxo-11α,16-Dihydroxy-16-methyl-(8β)-prost-13E-en-1-oic Acid Methyl Ester. Grades: > 95%. CAS No. 1256643-55-6. Molecular formula: C22H38O5. Mole weight: 382.53. | |
| 8-O-Demethyl Ivabradine HCl | Synonyms: 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-8-hydroxy-7-methoxy-2H-3-benzazepin-2-one HCl. Grades: > 95%. Molecular formula: C26H35ClN2O5. Mole weight: 491.03. | |
| 8-Oxo-desacetylated famciclovir | An impurity of Famciclovir. Famciclovir is used for the treatment of various herpesvirus infections, most commonly for herpes zoster. Synonyms: 4-(2-amino-8-oxo-7H-purin-9(8H)-yl)-2-(hydroxymethyl)butyl acetate. Grades: > 95%. Molecular formula: C12H17N5O4. Mole weight: 295.30. | |
| 9-Acetyl Latanoprost | An analog of Latanoprost, a prostaglandin analog, used to treat glaucoma and other degenerative diseases of the eye. Grades: > 95%. Molecular formula: C28H42O6. Mole weight: 474.64. | |
| 9-Didemethyl Minocycline | Cas No. 5874-95-3. | |
| 9-Monodemethyl Minocycline | 9-Monodemethyl Minocycline is a tetracycline derivative used in antibiotic pharmaceutical compositions. Grades: > 95%. CAS No. 4769-39-5. Molecular formula: C22H25N3O7. Mole weight: 443.45. | |
| (9S)-9-Deoxo-12-deoxy-9,12-epoxyerythromycin | (9S)-9-Deoxo-12-deoxy-9,12-epoxyerythromycin is a derivative of Erythromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: Erythromycin, 9-deoxo-12-deoxy-9,12-epoxy-, (9S)-; (1R,2R,5R,6S,7S,8R,11R,12S,13S)-8-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-9-hydroxy-6-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-1,5,7,9,11,13-hexamethyl-3,15-dioxabicyclo[10.2.1]pentadecane-4,14-dione. Grades: >95%. CAS No. 134108-11-5. Molecular formula: C37H68N2O13. Mole weight: 715.91. | |
| [Ala107]-MBP (104-118) acetate | [Ala107]-MBP (104-118) acetate is a non-competitive inhibitor of PKC with an IC50 value of 46-145 mM. It is a synthetic peptide analog of bovine myelin basic protein (MBP). Synonyms: H-Gly-Lys-Gly-Ala-Gly-Leu-Ser-Leu-Ser-Arg-Phe-Ser-Trp-Gly-Ala-OH.CH3CO2H; glycyl-L-lysyl-glycyl-L-alanyl-glycyl-L-leucyl-L-seryl-L-leucyl-L-seryl-L-arginyl-L-phenylalanyl-L-seryl-L-tryptophyl-glycyl-L-alanine acetate; [Ala107]-Myelin Basic Protein (104-118) acetate. Grades: ≥95%. Molecular formula: C67H104N20O19.C2H4O2. Mole weight: 1553.74. | |
| (Ala11.22.28)-VIP (human, mouse, rat) | (Ala11.22.28)-VIP (human, mouse, rat), a highly selective human VPAC1 receptor agonist, shows a 1000-fold higher efficiency in stimulating adenylate cyclase activity from VPAC1 than VPAC2 receptors. It is a valid pharmacological tool for characterizing VPAC1 receptor-mediated events. Synonyms: (Ala11.22.28)-Aviptadil; H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Ala-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Ala-Leu-Asn-Ser-Ile-Leu-Ala-NH2; L-histidyl-L-seryl-L-alpha-aspartyl-L-alanyl-L-valyl-L-phenylalanyl-L-threonyl-L-alpha-aspartyl-L-asparagyl-L-tyrosyl-L-alanyl-L-arginyl-L-leucyl-L-arginyl-L-lysyl-L-glutaminyl-L-methionyl-L-alanyl-L-valyl-L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-asparagyl-L-seryl-L-isoleucyl-L-leucyl-L-alaninamide. Grades: ≥95% by HPLC. CAS No. 291524-04-4. Molecular formula: C139H231N43O39S. Mole weight: 3160.65. | |
| [Ala113]-MBP (104-118) acetate | [Ala113]-MBP (104-118) acetate is a non-competitive inhibitor of PKC with IC50 of 28-62 μM. It is a synthetic peptide analog of bovine myelin basic protein (MBP). Synonyms: H-Gly-Lys-Gly-Arg-Gly-Leu-Ser-Leu-Ser-Ala-Phe-Ser-Trp-Gly-Ala-OH.CH3CO2H; Glycyl-L-lysyl-glycyl-L-arginyl-glycyl-L-leucyl-L-seryl-L-leucyl-L-seryl-L-alanyl-L-phenylalanyl-L-seryl-L-tryptophyl-glycyl-L-alanine acetic acid; [Ala113]-MBP acetate. Grades: ≥95%. Molecular formula: C69H108N20O21. Mole weight: 1553.74. | |
| (Ala13)-Apelin-13 acetate salt (human, bovine, mouse, rat) | (Ala13)-Apelin-13 acetate salt (human, bovine, mouse, rat) is an antioxidant with the ability to scavenge active oxygen species such as superoxide and hydroxyl radicals, and may have therapeutic effects on diseases (such as arthritis and cancer) damaged by hydroxyl radicals. Synonyms: H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala-OH acetate salt; L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysyl-glycyl-L-prolyl-L-methionyl-L-prolyl-L-alanine acetate salt. Molecular formula: C63H107N23O16S.C2H4O2. Mole weight: 1534.81. | |
| (Ala13)-Apelin-13 (human, bovine, mouse, rat) | (Ala13)-Apelin-13 (human, bovine, mouse, rat) is an antioxidant with the ability to scavenge active oxygen species such as superoxide and hydroxyl radicals, and may have therapeutic effects on diseases (such as arthritis and cancer) damaged by hydroxyl radicals. Synonyms: (Ala13)-Apelin 13, human; H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala-OH; L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysyl-glycyl-L-prolyl-L-methionyl-L-prolyl-L-alanine; L-Glutaminyl-N5-(diaminomethylene)-L-ornithyl-L-prolyl-N5-(diaminomethylene)-L-ornithyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-alanine; Apelin 13 F13A. Grades: ≥95%. CAS No. 568565-11-7. Molecular formula: C63H107N23O16S. Mole weight: 1474.73. | |
| (Ala1)-PAR-4 (1-6) (mouse) | (Ala1)-PAR-4 (1-6) (mouse) is a peptide used in compound to study the role of PAR-4 (Prostate Apoptosis Response 4) in mice. It is specifically designed to mimic the first six amino acids of mouse PAR-4 and is utilized to investigate its function and potential therapeutic targets in diseases such as cancer and apoptosis-related disorders. Synonyms: (Ala1)-Thrombin Receptor-Like 3 (1-6) (mouse); H-AYPGKF-OH; L-alanyl-L-tyrosyl-L-prolyl-glycyl-L-lysyl-L-phenylalanine; (Ala1)-Proteinase Activated Receptor 4 (1-6) (Mouse); (Ala1)-Coagulation Factor II Receptor-Like 3 (1-6) (Mouse). Grades: ≥95%. CAS No. 380900-00-5. Molecular formula: C34H47N7O8. Mole weight: 681.78. | |
| (Ala2)-Endothelin-3 (human, mouse, rabbit, rat) | Synonyms: (Ala2)-ET-3 (human, mouse, rat); H-Cys-Ala-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Disulfide bridge: Cys1-Cys15, Cys3-Cys11); L-Tryptophan, L-cysteinyl-L-alanyl-L-cysteinyl-L-phenylalanyl-L-threonyl-L-tyrosyl-L-lysyl-L-α-aspartyl-L-lysyl-L-α-glutamyl-L-cysteinyl-L-valyl-L-tyrosyl-L-tyrosyl-L-cysteinyl-L-histidyl-L-leucyl-L-α-aspartyl-L-isoleucyl-L-isoleucyl-, cyclic(1?15),(3?11)-bis(disulfide). Grades: ≥95%. CAS No. 2243207-08-9. Molecular formula: C120H166N26O32S4. Mole weight: 2613.06. | |
| [Ala5, beta-Ala8]-Neurokinin A (4-10) | It is a potent and selective agonist of NK-2 receptor. Synonyms: L-alpha-aspartyl-L-alanyl-L-phenylalanyl-L-valyl-beta-alanyl-L-leucyl-L-methioninamide; L-Methioninamide, L-α-aspartyl-L-alanyl-L-phenylalanyl-L-valyl-β-alanyl-L-leucyl-; (5S,8S,15S,18S,21S,24S)-24-Amino-18-benzyl-5-carbamoyl-8-isobutyl-15-isopropyl-21-methyl-7,10,14,17,20,23-hexaoxo-2-thia-6,9,13,16,19,22-hexaazahexacosan-26-oic acid; Asp-Ala-Phe-Val-β-Ala-Leu-Met-NH2; [ala5,β-ala8]-α-neurokinin fragment 4-10. Grades: ≥95%. CAS No. 127633-71-0. Molecular formula: C35H56N8O9S. Mole weight: 764.93. | |
| α1-Mating Factor TFA salt | Alpha1-Mating Factor a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor, facilitates in regulating the mating in yeast. Synonyms: α-Factor Mating Pheromone, yeast (TFA salt); Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr.TFA; Mating Factor α TFA salt. Molecular formula: C82H114N20O17S (free base). Mole weight: 1683.97 (free base). | |
| α2β1 Integrin Ligand Peptide acetate | α2β1 Integrin Ligand Peptide acetate is a potential antagonist of the α2β1 integrin receptor that interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors. Synonyms: DGEA acetate; H-Asp-Gly-Glu-Ala-OH acetate; a2b1 Integrin Recognition Sequence acetate; H-Asp-Gly-Glu-Ala-OH.CH3CO2H; L-alpha-aspartyl-glycyl-L-alpha-glutamyl-L-alanine acetic acid. Grades: ≥95%. CAS No. 2763588-78-7. Molecular formula: C16H26N4O11. Mole weight: 450.40. | |
| α,4-Dimethylphenylacetic acid | Cas No. 938-94-3. | |
| α-amanitin | Cas No. 23109-05-9. | |
| α-Conotoxin EI (free acid) | α-Conotoxin EI (free acid) is a nicotinic acetylcholine receptor ligand. Synonyms: α-Conotoxin El, Conus ermineus, free acid; H-Arg-Asp-Hyp-Cys-Cys-Tyr-His-Pro-Thr-Cys-Asn-Met-Ser-Asn-Pro-Gln-Ile-Cys-OH (Disulfide bridge: Cys4-Cys10, Cys5-Cys18). Grades: ≥95%. CAS No. 1926163-14-5. Molecular formula: C83H124N26O28S5. Mole weight: 2094.37. | |
| α-Conotoxin MI | α-Conotoxin MI has been isolated from the venom of the sea snail Conus imperialis. The conotoxin is a ligand for nicotinic acetylcholine receptors. Synonyms: Alpha-Conotoxin MI; Conotoxin G I, 1-(N2-glycyl-L-arginine)-4-L-histidine-9-L-lysine-10-L-asparagine-. CAS No. 88217-10-1. Molecular formula: C58H88N22O17S4. Mole weight: 1493.72. | |
| α-Cyclohexylmandelic acid | An impurity of Oxybutynin which is a prescription drug to reduce muscle spasms of the bladder and urinary tract. Synonyms: 2-cyclohexyl-2-hydroxy-2-phenylacetic acid. Grades: 98 %. CAS No. 4335-77-7. Molecular formula: C14H18O3. Mole weight: 234.29. | |
| α-Factor Mating Pheromone, yeast acetate | α-Factor Mating Pheromone, yeast acetate is a tridecapeptide secreted by Saccharomyces cerevisiae α cells via the Ste2p receptor, which facilitates in regulating the mating in yeast. Synonyms: H-Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr-OH.CH3CO2H; Mating Factor α acetate; alphaSC1-Pheromone acetate; L-tryptophyl-L-histidyl-L-tryptophyl-L-leucyl-L-glutaminyl-L-leucyl-L-lysyl-L-prolyl-glycyl-L-glutaminyl-L-prolyl-L-methionyl-L-tyrosine acetic acid. Grades: ≥95%. Molecular formula: C84H118N20O19S. Mole weight: 1744.05. | |
| α-helical CRF 9-41 acetate | α-helical CRF 9-41 acetate, a salt of α-helical CRF 9-41 that is a competitive CRF2 receptor antagonist and a partial agonist of CRF1 receptor. Grades: >95.0%. Molecular formula: C168H276N46O54S2. Mole weight: 3868.44. | |
| α-Lobeline Hydrochcloride | α-Lobeline Hydrochcloride is a neuronal nicotinic acetylcholine receptor agonist. It is also a CNS stimulant. Uses: The hydrochloride salt form of α-lobeline is a nicotinic receptor agonist that could be used against asphyxia and respiratory failure. Synonyms: 2-[(2R,6S)-6-[(2S)-2-Hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenylethanone Hydrochloride; Lobeline Hydrochloride; (-)-Lobeline Hydrochloride; (-)-α-Lobeline Hydrochloride; Lobelin Hydrochloride; Lobron; Zoolobelin. Grades: > 95%. CAS No. 134-63-4. Molecular formula: C22H28ClNO2. Mole weight: 373.92. | |
| α-MSH free acid | α-MSH is an MC3R and MC4R agonist with EC50s of 0.16 nM and 5.6 nM, respectively. It activates cAMP generation at MC3R and MC4R. Synonyms: (D-Leu2)-MIF-I; 13-Val-alpha-msh (1-13); alpha-Msh(1-13), valine(13)-; α-Melanocyte-Stimulating Hormone free acid. Grades: >95%. CAS No. 10466-28-1. Molecular formula: C77H108N20O20S. Mole weight: 1665.87. | |
| α-Naphthocyclinone | Synonyms: 6, 13-Methanonaphtho[2', 3':5, 6]cyclohepta[1, 2-g]-2-benzopyran-9-butanoic acid, 6-(acetyloxy)-1,3,4,6,8,11,13,14-octahydro-β,7,10,12,15-pentahydroxy-3-(2-methoxy-2-oxoethyl)-1-methyl-8,11,14-trioxo-, (βR,1S,3R,6S,13R)-; alpha-Naphthocyclinone; (R)-4-((1S, 3R, 6S, 13R)-6-acetoxy-7, 8, 12, 15-tetrahydroxy-3-(2-methoxy-2-oxoethyl)-1-methyl-10, 11, 14-trioxo-1, 3, 4, 6, 10, 11, 13, 14-octahydro-6, 13-methanonaphtho[2', 3':5, 6]cyclohepta[1, 2-g]isochromen-9-yl)-3-hydroxybutanoic acid; a-Naphthocyclinone. CAS No. 54826-93-6. Molecular formula: C33H30O15. Mole weight: 666.58. | |
| α-Synuclein (32-37) (human) | Synonyms: α-Synuclein (43-48) (human); H-Lys-Thr-Lys-Glu-Gly-Val-OH; L-Valine, L-lysyl-L-threonyl-L-lysyl-L-α-glutamylglycyl-; L-lysyl-L-threonyl-L-lysyl-L-alpha-glutamyl-glycyl-L-valine; H-KTKEGV-OH. Grades: ≥95%. CAS No. 865377-33-9. Molecular formula: C28H52N8O10. Mole weight: 660.76. | |
| α-Synuclein (34-45) (human) | The Parkinson's disease-associated protein α-synuclein (α-syn) is not only expressed in the cytoplasm of neurons, but also secreted in the extracellular space and internalized into glial cells through a lipid raft dependent process. The tilted peptide α-synuclein(67-78) has a high affinity with cholesterol and is toxic to cultured astrocytes. The glycosphingolipid-binding domain of alpha-synuclein (34-45) encapsulates a cholesterol-recognition consensus motif with a low affinity and no toxicity. Synonyms: α-syn (34-45) (human); H-Lys-Glu-Gly-Val-Leu-Tyr-Val-Gly-Ser-Lys-Thr-Lys-OH; L-Lysine, L-lysyl-L-α-glutamylglycyl-L-valyl-L-leucyl-L-tyrosyl-L-valylglycyl-L-seryl-L-lysyl-L-threonyl-. Grades: ≥95%. CAS No. 2170181-52-7. Molecular formula: C59H101N15O18. Mole weight: 1308.52. | |
| α-Synuclein (45-54) (human) | A pathogenic feature of Parkinson's disease (PD) is the aggregation of α-synuclein (α-syn) into toxic fibrils, and most of the early mutations are located between residues 46 and 53. Synonyms: H-Lys-Glu-Gly-Val-Val-His-Gly-Val-Ala-Thr-OH; L-Threonine, L-lysyl-L-α-glutamylglycyl-L-valyl-L-valyl-L-histidylglycyl-L-valyl-L-alanyl-; α-syn (45-54) (human). Grades: ≥95%. CAS No. 2243206-98-4. Molecular formula: C43H73N13O14. Mole weight: 996.12. | |
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