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PG 97-269
PG 97-269, a selective high affinity VPAC1 receptor antagonist, has negligible affinity for PACAP type I receptors, with Kis of 15±5 and 2±1 nM for the rat and human VPAC1 receptors, respectively. It can be used to evaluate the physiological role of VIP in rats and human tissues. Synonyms: Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27); Ac-His-D-Phe-Asp-Ala-Val-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Lys-Arg-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-NH2; L-Leucinamide, N-acetyl-L-histidyl-D-phenylalanyl-L-α-aspartyl-L-alanyl-L-valyl-L-phenylalanyl-L-threonyl-L-asparaginyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-L-lysyl-L-arginyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-isoleucyl-. Grades: ≥95%. CAS No. 202463-00-1. Molecular formula: C150H246N44O38. Mole weight: 3273.83.
PGLa acetate
PGLa is an antimicrobial peptide (AMP) composed of 21 amino acids which form an alpha-helical secondary structure. It has a wide variety of antimicrobial activity including activity against fungi, viruses, gram-negative and gram-positive bacteria, and cancer cells. Synonyms: PYLa/PGLa precursor acetate; Gla peptide acetate. Molecular formula: C90H166N26O24S. Mole weight: 2028.51.
ACTH (1-24) is a fragment of the ACTH hormone, which stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. Synonyms: 2-Phenylalanyl-4-norleucine-acth(1-24); ACTH (1-24), phe(2)-nle(4)-; alpha1-24-Corticotropin, 2-L-phenylalanine-4-L-norleucine-; (Phe2,Nle4)-ACTH (1-24) (human, bovine, rat). CAS No. 97773-00-7. Molecular formula: C137H212N40O30. Mole weight: 2899.40.
Phe-Met-Arg-Phe Like Peptide acetate
Phe-Met-Arg-Phe Like Peptide acetate is an FMRF-like peptide derived from the visceral and somatic muscles of the Snail Helix aspersa. FMRF (Phe-Met-Arg-Phe) is a neuropeptide peptide composed of 4 amino acid residues. Synonyms: Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersa, acetate; H-Pyr-Asp-Pro-Phe-Leu-Arg-Phe-NH2.CH3CO2H; L-pyroglutamyl-L-alpha-aspartyl-L-prolyl-L-phenylalanyl-L-leucyl-L-arginyl-L-phenylalaninamide acetate; 5-Oxo-L-prolyl-L-α-aspartyl-L-prolyl-L-phenylalanyl-L-leucyl-L-arginyl-L-phenylalaninamide acetate. Grades: ≥95%. Molecular formula: C46H65N11O12. Mole weight: 964.07.
Phenarctin
Phenarctin is obtained from Nephroma arcticum. Synonyms: 3-Hydroxy-4-(methoxycarbonyl)-2,5,6-trimethylphenyl 3,5-diformyl-2,4-dihydroxy-6-methylbenzoate; β-Resorcylic acid, 3,5-diformyl-6-methyl-, 4-ester with methyl 3,5,6-trimethyl-β-resorcylate (8CI). CAS No. 27839-39-0. Molecular formula: C21H20O9. Mole weight: 416.38.
It is produced by the strain of Str. sp. 833. It is a phenazine Substance that has the protective effect of new neuron cells. It can scavenge free radicals, protect N18-RE 105 nerve cells from glutamate toxicity, and inhibit lipid peroxidation. It inhibits glutamate toxicity in N18-RE-105 cells with EC50 of 0.34 μg/mL. Molecular formula: C28H20N4O3. Mole weight: 460.48.
Phenazostatin B
It is produced by the strain of Str. sp. 833. It is a phenazine Substance that has the protective effect of new neuron cells. It can scavenge free radicals, protect N18-RE 105 nerve cells from glutamate toxicity, and inhibit lipid peroxidation. It inhibits glutamate toxicity in N18-RE-105 cells with EC50 of 0.33 μg/mL. Molecular formula: C32H26N4O4. Mole weight: 530.57.
Phenazostatin C
It is produced by the strain of Streptomyces sp. 833. It can protect N18-RE-105 nerve cells from glutamate toxicity with EC50 of 0.37 μmol/L (similar to Phenazinastatin A) and inhibit lipid peroxidation. It has low toxicity, and 100 μmol/L of Phenazostatin C is not cytotoxic. Molecular formula: C30H22N4O4. Mole weight: 502.52.
Phenformin HCl
Cas No. 834-28-6.
Phenindione
Phenindione is an anticoagulant which functions as a Vitamin K antagonist. Uses: Anticoagulants. Synonyms: phenindione; 83-12-5; 2-Phenyl-1,3-indandione2-Phenyl-1H-indene-1,3(2H)-dione; Rectadione. Grades: >98%. CAS No. 83-12-5. Molecular formula: C15H10O2. Mole weight: 222.24.
Phenprocoumon
Phenprocoumon, a derivative of coumarin, is known for being an oral anti-coagulant. Uses: Anticoagulant. Synonyms: 4-Hydroxy-3-(1-phenylpropyl)-2H-1-benzopyran-2-one; 3-(α-Ethylbenzyl)-4-hydroxy-coumarin; (±)-Phenprocoumon; 3-(1-Phenylpropyl)-4-hydroxycoumarin; 3-(α-Ethylbenzyl)-4-hydroxycoumarin. Grades: ≥95%. CAS No. 435-97-2. Molecular formula: C18H16O3. Mole weight: 280.32.
Phenylalanyl-histidine
Phenylalanylhistidine is a dipeptide composed of phenylalanine and histidine. Synonyms: Phe-his; L-phenylalanyl-L-histidine. CAS No. 33367-37-2. Molecular formula: C15H18N4O3. Mole weight: 302.33.
Phenylalanyl-lysine
Phenylalanyl-lysine is a dipeptide composed of phenylalanine and lysine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: 3-Phenyl-L-Ala-L-Lys-OH; L-Phe-L-Lys-OH; N2-(3-Phenyl-L-alanyl)-L-lysine; Phe-Lys-OH; L-Lysine, L-phenylalanyl-; (S)-6-Amino-2-((S)-2-amino-3-phenyl-propionylamino)-hexanoic acid; H-FK-OH; L-phenylalanyl-L-lysine. Grades: ≥95%. CAS No. 6456-72-0. Molecular formula: C15H23N3O3. Mole weight: 293.36.
Phenylalanyl-threonine
Phenylalanyl-threonine is a dipeptide composed of phenylalanine and threonine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Threonine, L-phenylalanyl-; Phe-Thr; H-FT-OH; L-Phe-L-Thr; L-phenylalanyl-L-threonine. Grades: ≥98%. CAS No. 51352-44-4. Molecular formula: C13H18N2O4. Mole weight: 266.29.
Phenylbutazone
Phenylbutazone is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis. In the United States and United Kingdom, it is no longer approved for human use, as it can cause severe adverse effects such as suppression of white blood cell production and aplastic anemia. Synonyms: Butazolidine. Grades: >98%. CAS No. 50-33-9. Molecular formula: C19H20N2O2. Mole weight: 308.37.
Phenyl disulfide
An impurity of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-5 protease inhibitor. Synonyms: (phenyldisulfanyl)benzene. Grades: 97 %. CAS No. 882-33-7. Molecular formula: C12H10S2. Mole weight: 218.34.
PHE-PHE-PHE-PHE
Tetraphenylalanine could be assembled into ordered autofluorescent elongated structures. Grades: ≥97%. CAS No. 2667-2-9. Molecular formula: C36H38N4O5. Mole weight: 606.71.
PHF6
The sequence VQIVYK in the third tau repeats is crucial for fibrillization. Synonyms: Paired helical filament-6 Tau Protein (306-311) (human); H-Val-Gln-Ile-Val-Tyr-Lys-OH; H-VQIVYK-OH; L-valyl-L-glutaminyl-L-isoleucyl-L-valyl-L-tyrosyl-L-lysine. Grades: ≥95%. CAS No. 329897-62-3. Molecular formula: C36H60N8O9. Mole weight: 748.92.
PHI-27 (porcine)
PHI-27 (porcine) belongs to the glucagon-secretin family and plays a key role in the generation of circadian oscillations. It has bioactivity similar to vasoactive intestinal peptide (VIP) and secretin. Synonyms: PHI (PHI-27), porcine; H-His-Ala-Asp-Gly-Val-Phe-Thr-Ser-Asp-Phe-Ser-Arg-Leu-Leu-Gly-Gln-Leu-Ser-Ala-Lys-Lys-Tyr-Leu-Glu-Ser-Leu-Ile-NH2; L-histidyl-L-alanyl-L-alpha-aspartyl-glycyl-L-valyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-phenylalanyl-L-seryl-L-arginyl-L-leucyl-L-leucyl-glycyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-L-seryl-L-leucyl-L-isoleucinamide. Grades: ≥95%. CAS No. 80458-29-3. Molecular formula: C136H216N36O40. Mole weight: 2995.39.
Phleomycin B2
It is produced by the strain of Streptoverticillium verticillum 843-1. It's a heteropeptide antibiotic. It has anti-gram-positive bacteria, negative bacteria and mycobacterium effects. Synonyms: Epi-Bleomycin; Dehydrophleomycin D1; Zhengguanmycin B2; N1-[4-[[Amino (imino) methyl]amino]butyl]bleomycinamide; Bleomycin B2; Bleomycinamide, N1-(4-((aminoiminomethyl)amino)butyl)-. CAS No. 9060-10-0. Molecular formula: C55H84N20O21S2. Mole weight: 1425.51.
Phleomycin D1
It is produced by the strain of Streptoverticillium verticillum 843-1. It's a heteropeptide antibiotic. It has anti-gram-positive bacteria, negative bacteria and mycobacterium effects. It extends the survival time of mice transplanted with Ehrman's ascites cancer by 300 percent with MED of 12.5-25 μg/mL. It inhibits airy entity carcinoma in mice with IC50 of 0.31 μg/mL. Synonyms: Zeocin; Zeocine; (7R)-N1-[4-[[Amino(imino)methyl]amino]butyl]-7,8-dihydrobleomycinamide; Bleomycinamide, N1-[4-[(aminoiminomethyl)amino]butyl]-7,8-dihydro-. Grades: 95%. CAS No. 11031-11-1. Molecular formula: C55H86N20O21S2. Mole weight: 1427.52.
Phoenistatin
It is produced by the strain of Acremonium fusigerum. It's a substance that increases the expression of genes. 3 nmol/L - 1000 μmol/L of Phoenistatin causes more than 3 times the gene expression of the PA1-1 promoter. Molecular formula: C29H40N4O6. Mole weight: 540.65.
Phosmidosine C
It is produced by the strain of Str. sp. RK-16. Molecular formula: C11H17N6O7P. Mole weight: 376.26.
Physodalic acid
It is a lichen depsidone isolated from Hypogymnia physodes. Synonyms: 4-(acetyloxymethyl)-10-formyl-3,9-dihydroxy-1,7-dimethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylic acid; CCRIS 5525; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 9-[(acetyloxy)methyl]-4-formyl-3,8-dihydroxy-1,6-dimethyl-11-oxo-. CAS No. 90689-60-4. Molecular formula: C20H16O10. Mole weight: 416.33.
Picrolichenic acid
It is a 3-spirobenzofuran heterocyclic compound isolated from Variolaria amara. Synonyms: 6-Hydroxy-2'-methoxy-2,4'-dioxo-4,6'-dipentylspiro[benzofuran-3(2H),1'-[2,5]cyclohexadiene]-5-carboxylic acid; Pikrolichenic acid; Spiro[benzofuran-3(2H),1'-[2,5]cyclohexadiene]-5-carboxylic acid, 6-hydroxy-2'-methoxy-2,4'-dioxo-4,6'-dipentyl-; picrolichenin; NSC 43331; 6-hydroxy-2'-methoxy-2,4'-dioxo-4,6'-dipentyl-2H-spiro[benzofuran-3,1'-cyclohexane]-2',5'-diene-5-carboxylic acid. CAS No. 466-34-2. Molecular formula: C25H30O7. Mole weight: 442.50.
Pillaromycin A
It is produced by the strain of Str. flavovirens 65786. It has anti-mycobacteria, gram-positive bacteria and gram-negative bacteria effects, but the effect of anti-gram-negative bacteria is weak. It also has antitumor activity similar to colchicine. Synonyms: 5(1H)-Naphthacenone, 2,4a,12,12a-tetrahydro-3-acetyl-4a-((tetrahyro-5-hydroxy-5(hydroxyacetyl)-6-methyl-2H-pyran-2-yl)oxy)-1,2,6,7-tetrahydroxy-, (1R-(1-alpha,2-alpha,4a-alpha(2S*,5S*,6S*),12a-alpha))-; 5(1H)-Naphthacenone,3-acetyl-2,4a,12,12a-tetrahydro-1,2,6,7-tetrahydroxy-4a-[[(2S,5S,6S)-tetrahydro-5-hydroxy-5-(hydroxyacetyl)-6-methyl-2H-pyran-2-yl]oxy]-, (1R,2S,4aR,12aR)-; NSC 102812. CAS No. 30361-37-6. Molecular formula: C28H30O11. Mole weight: 542.53.
Pimavanserin-d4
Cas No. 706779-91-1.
Pinastric acid
It is a derivative of pulvinic acid and isolated from a terrestrial lichen. It displays antitumour, antiviral and antimicrobial (both antibacterial and antifungal) activities. Synonyms: 4'-Methoxyvulpinic acid; Pianstric acid; (αE)-α-Phenyl-3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylideneacetic acid methyl ester; 2-Phenyl-2-[(2E)-3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylidene]acetic acid methyl ester; Phenyl[(2E)-3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylidene]acetic acid methyl ester; α-[(2E)-3-Hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylidene]benzeneacetic acid methyl ester; Benzeneacetic acid, α-[3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2(5H)-furanylidene]-, methyl ester, (αE)-; methyl (E)-2-(3-hydroxy-4-(4-methoxyphenyl)-5-oxofuran-2(5H)-ylidene)-2-phenylacetate; δ2(5H),α-Furanacetic acid, 3-hydroxy-4-(p-methoxyphenyl)-5-oxo-α-phenyl-, methyl ester. CAS No. 481-64-1. Molecular formula: C20H16O6. Mole weight: 352.34.
Pinealon acetate
Pinealon acetate has antioxidant activity and can directly interact with the cell genome. Synonyms: H-Glu-Asp-Arg-OH.CH3CO2H; EDR.CH3CO2H; L-alpha-glutamyl-L-alpha-aspartyl-L-arginine acetic acid; L-Arginine, N2-(N-L-α-glutamyl-L-α-aspartyl)-, acetate salt; L-α-Glutamyl-L-α-aspartyl-L-arginine acetate salt. Grades: ≥95%. CAS No. 2703745-42-8. Molecular formula: C17H30N6O10. Mole weight: 478.45.
Pipotiazine is a typical antipsychotic of the phenothiazine class used for the maintenance treatment of chronic non-agitated schizophrenic patients. Symptoms of overdose include severe extrapyramidal manifestations, hypotension, lethargy and sedation. Uses: A typical antipsychotic of the phenothiazine class. Synonyms: RP 19366; RP-19366; RP19366; 10-[3-[4-(2-hydroxyethyl)piperidin-1-yl]propyl]-N,N-dimethylphenothiazine-2-sulfonamide. Grades: ≥98%. CAS No. 39860-99-6. Molecular formula: C24H33N3O3S2. Mole weight: 475.675.
Pirfenidone-d5
Cas No. 1020719-62-3.
Pironetin
Pironetin is a plant growth regulator produced by Streptomyces sp. NK10958. Synonyms: PA 48153C. CAS No. 151519-02-7. Molecular formula: C19H32O4. Mole weight: 324.5.
Piroxicam
Piroxicam is a non-selective COX inhibitor with an IC50 of 6 mM. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: CP 16171; CP16171; CP-16171. Grades: >98%. CAS No. 36322-90-4. Molecular formula: C15H13N3O4S. Mole weight: 331.35.
Piroxicam Impurity 1
An impurity of Piroxicam which is a nonsteroidal anti-inflammatory drug. Grades: > 95%. Molecular formula: C18H19N3O4S. Mole weight: 373.43.
Piroxicam Impurity B
An impurity of Piroxicam which is an anti-inflammatory drug used for the treatment of inflammation and pain caused by rheumatoid arthritis or osteoarthritis. Synonyms: 4-Hydroxy-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide. Grades: > 95%. CAS No. 65897-46-3. Molecular formula: C14H11N3O4S. Mole weight: 317.33.
Piroxicam Impurity C
An impurity of Piroxicam which is a nonsteroidal anti-inflammatory drug. Synonyms: 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide. Grades: > 95%. CAS No. 24683-25-8. Molecular formula: C10H10N2O4S. Mole weight: 254.27.
Piroxicam Impurity D
An impurity of Piroxicam which is used for the treatment of inflammation and pain caused by rheumatoid arthritis or osteoarthritis. Synonyms: 3-Oxo-1,2-benzoisothiazoline-2-acetic Acid Methyl Ester 1,1-Dioxide; Saccharin N-(2-Acetic Acid Methyl Ester); NSC 49216. Grades: > 95%. CAS No. 6639-62-9. Molecular formula: C10H9NO5S. Mole weight: 255.25.
Piroxicam impurity F
An impurity of Piroxicam which is a non-selective COX inhibitor with an IC50 of 6 mM. Synonyms: 3-Oxo-1,2-benzisothiazole-2(3H)-acetic Acid 1-Methylethyl Ester 1,1-Dioxide; 1-Methylethyl (1,1-Dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)acetate; Isopropyl 3-Oxo-1,2-benzisothiazole-2(3H)acetate 1,1-Dioxide. Grades: > 95%. CAS No. 76508-37-7. Molecular formula: C12H13NO5S. Mole weight: 283.31.
Piroxicam Impurity G
An impurity of Piroxicam which is an anti-inflammatory drug used for the treatment of inflammation and pain caused by rheumatoid arthritis or osteoarthritis. Synonyms: 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylic Acid Methyl Ester 1,1-Dioxide; Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide. Grades: > 95%. CAS No. 35511-14-9. Molecular formula: C10H9NO5S. Mole weight: 255.25.
Piroxicam Impurity I
An impurity of Piroxicam which is used for the treatment of inflammation and pain caused by rheumatoid arthritis or osteoarthritis. Synonyms: 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylic Acid 1-Methylethyl Ester 1,1-Dioxide; 1-Methylethyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide; NSC 642708. Grades: > 95%. CAS No. 76508-35-5. Molecular formula: C12H13NO5S. Mole weight: 283.31.
Piroxicam Impurity J
Methyl 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide is the Piroxicam Impurity J. It Is also an impurity found in Meloxicam. Synonyms: Methyl 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide; 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic Acid Methyl Ester 1,1-Dioxide; Piroxicam Impurity J. Grades: > 95%. CAS No. 35511-15-0. Molecular formula: C11H11NO5S. Mole weight: 269.27.
Piroxicam impurity L
Isopropyl 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide is a Piroxicam Impurity L. It is also an impurity found in meloxicam. Synonyms: Isopropyl 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide; 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic Acid 1-Methylethyl Ester 1,1-Dioxide; 1-Methylethyl 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide; NSC 64. Grades: > 95%. CAS No. 118854-48-1. Molecular formula: C13H15NO5S. Mole weight: 297.33.
Pittosapogenin
Pittosapogenin is a triterpenoid compound. CAS No. 15399-43-6. Molecular formula: C30H50O6. Mole weight: 506.71.
Pixantrone Dimaleate
Pixantrone is a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Pixantrone is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non-Hodgkin lymphoma (aNHL). Uses: Topoisomerase ii inhibitors. Synonyms: BBR 2778; BBR2778; BBR-2778; 6,9-Aea-biqdo; D05522; 5,8-Bis((2-aminoethyl)amino)-2-aza-anthracene-9,10-dione. Grades: >98%. CAS No. 144675-97-8. Molecular formula: C17H19N5O2.2C4H4O4??. Mole weight: 557.52.
PKA inhibitor fragment (6-22) amide acetate
PKA Inhibitor Fragment (6-22) amide acetate is a synthetic peptide inhibitor of cAMP-dependent protein kinase (PKA) (Ki = 2.5 nM), derived from the heat-stable PKA inhibitor protein PKI. It is the shortest synthetic PKI peptide that retains high potency for PKA inhibition. Synonyms: H-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2.CH3CO2H; L-threonyl-L-tyrosyl-L-alanyl-L-alpha-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-seryl-glycyl-L-arginyl-L-threonyl-glycyl-L-arginyl-L-arginyl-L-asparagyl-L-alanyl-L-isoleucinamide acetic acid. Grades: ≥95%. Molecular formula: C82H134N28O26. Mole weight: 1928.11.
PKC ζ pseudosubstrate acetate
PKC ζ pseudosubstrate acetate, a synthetic peptide, is an inhibitor of protein kinase C (PKC) ζ that is attached to cell permeabilization Antennapedia domain vector peptide. It consists of amino acids 113-129 PKC ζ pseudosubstrate domains connected by a disulfide bridge to the cell permeabilization Antennapedia domain vector peptide. Synonyms: Protein kinase C zeta pseudosubstrate acetate; L-cysteinyl-L-seryl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginyl-glycyl-L-alanyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-lysyl-L-leucyl-L-tyrosyl-L-arginyl-L-alanyl-L-asparagine (1->1')-disulfide compound with L-cysteinyl-L-arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-arginyl-L-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine; H-Cys-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-Tyr-Arg-Ala-Asn-OH.H-Cys-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-OH (Disulfide bridge: Cys1-Cys1'). Grades: ≥95%. Molecular formula: C210H340N74O46S3. Mole weight: 4733.68.
PKG inhibitor peptide TFA
PKG inhibitor peptide TFA is an ATP-competitive inhibitor of cGMP-dependent protein kinase (PKG) with a Ki of 86 μM. It is an analog of a substrate peptide corresponding to a phosphorylation site of histone H2B, and inhibits phosphorylation of intact histones by PKA. Synonyms: H-Arg-Lys-Arg-Ala-Arg-Lys-Glu-OH.TFA; L-arginyl-L-lysyl-L-arginyl-L-alanyl-L-arginyl-L-lysyl-L-glutamic acid trifluoroacetic acid; cGMP Dependent Kinase Inhibitor Peptide TFA. Grades: ≥95%. Molecular formula: C40H75F3N18O12. Mole weight: 1057.13.
PKG Substrate acetate
PKG Substrate acetate is a selective substrate for cGMP-dependent protein kinase (PKG). Synonyms: H-Arg-Lys-Arg-Ser-Arg-Ala-Glu-OH.CH3CO2H; L-arginyl-L-lysyl-L-arginyl-L-seryl-L-arginyl-L-alanyl-L-glutamic acid acetic acid. Grades: ≥95%. Molecular formula: C37H71N17O13. Mole weight: 962.08.
PKI (5-24) acetate
PKI (5-24) acetate is a competitive, non-reversible peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki = 2.3 nM). Synonyms: H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-OH.CH3CO2H; L-Threonyl-L-threonyl-L-tyrosyl-L-alanyl-L-α-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-serylglycyl-L-arginyl-L-threonylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-alanyl-L-isoleucyl-L-histidyl-L-aspartic acid acetate salt; PKI(5-24) acetate salt. Grades: ≥95%. Molecular formula: C96H152N32O33. Mole weight: 2282.43.
Plactin A
Plactin A is a cyclic pentapeptide physiologically active substance produced by the fungus F165. It can promote the dissolution of fibrinolytic protein. Molecular formula: C32H52N8O6. Mole weight: 644.80.
Plactin B
Plactin B is a cyclic pentapeptide physiologically active substance produced by the fungus F165. It can promote the dissolution of fibrinolytic protein. Synonyms: Plastin B. Molecular formula: C32H52N8O6. Mole weight: 644.80.
Plactin C
Plactin C is a cyclic pentapeptide physiologically active substance produced by the fungus F165. It can promote the dissolution of fibrinolytic protein. Synonyms: cyclo(-D-Val-L-Leu-D-alloIle-L-Phe-D-Arg-). Molecular formula: C32H52N8O5. Mole weight: 628.80.
Plactin D
Plactin D is a cyclic pentapeptide physiologically active substance produced by the fungus F165. It can promote the dissolution of fibrinolytic protein. Synonyms: Plastin D; cyclo(-D-Val-L-Leu-D-Leu-L-Phe-D-Arg-). Molecular formula: C32H52N8O5. Mole weight: 628.80.
Planaic acid
It is produced by the strain of Lecidea plana and L.lithophila. Synonyms: Plana acid; Planasaeure; 2-Methoxy-4-(2,4-dimethoxy-6-pentylbenzoyloxy)-6-pentylbenzoic acid. CAS No. 5366-7-4. Molecular formula: C27H36O7. Mole weight: 472.57.
Pleuromutilin
It is produced by the strain of Drosophila subatrata. It is mainly anti-gram-positive bacterial activity. Synonyms: Drosophilin B; Drosopholin B; Mutilin 14-glycolate; (3aR,4R,5R,7S,8S,9R,9aS,12R)-8-hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-hydroxyacetate; Valnemulin impurity E; Glycolic acid, 8-dihydroxy-4,6,9,10-tetramethyl-6-vinyl-3a,9-propano-3aH-cyclopentacycloocten-1(4H)-one; antibiotic bc757. Grades: >95%. CAS No. 125-65-5. Molecular formula: C22H34O5. Mole weight: 378.50.
Plumieride
Plumieride is isolated from the herb of Himatanthus fallax. It shows strong fungitoxicity against some dermatophytes. Synonyms: Agoniadin. Grades: 98%. CAS No. 511-89-7. Molecular formula: C21H26O12. Mole weight: 470.42.
PMX 205 acetate
PMX 205 acetate is a potent complement C5a receptor antagonist (IC50 = 31 nM). It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma. PMX 205 reduces fibrillar amyloid deposits, decreases hyperphosphorylated tau levels and rescues cognitive function in a mouse model of Alzheimer's Disease. Synonyms: hydrocinnamoyl-Orn(1)-Pro-D-Cha-Trp-Arg-(1).CH3CO2H; L-Arginine, N2-(1-oxo-3-phenylpropyl)-L-ornithyl-L-prolyl-3-cyclohexyl-D-alanyl-L-tryptophyl-, (5?1)-lactam acetate; PMX205 acetate; PMX-205 acetate; Hydrocinnamate-(Orn-Pro-DCHA-Trp-Arg) acetate. Grades: ≥95%. Molecular formula: C47H66N10O8. Mole weight: 899.09.
PMX 53 acetate
PMX 53 is a potent and orally active C5aR(CD88) antagonist and Mas-related gene 2 (MrgX2) agonist. It stimulates MrgX2-mediated mast cell degranulation, inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis, inhibits lung metastasis in a mouse breast cancer model, and reduces atherosclerotic lesions in a mouse model of atherosclerosis. Synonyms: L-Arginine, N-acetyl-L-phenylalanyl-L-ornithyl-L-prolyl-3-cyclohexyl-D-alanyl-L-tryptophyl-, (6?2)-lactam, monoacetate; Ac-Phe-Orn(1)-Pro-D-Cha-Trp-Arg-(1).CH3CO2H; C 5aRA acetate salt. Grades: ≥95%. CAS No. 852629-88-0. Molecular formula: C47H65N11O7.C2H4O2. Mole weight: 956.14.
p-Nicorandil
An impurity of Nicorandil, which is potassium channel activator. Synonyms: N-[2-(Nitrooxy)ethyl]-4-pyridinecarboxamide; 2-Isonicotinamidoethyl nitrate; N-(2-Nitrooxyethyl)isonicotinamide. Grades: > 95%. CAS No. 65141-47-1. Molecular formula: C8H9N3O4. Mole weight: 211.18.
Polyalthic acid
Polyalthic acid is a naturally occurring diterpene found in copaiba oil and is reported to have anti-tumor activity. CAS No. 1235-76-3. Molecular formula: C20H28O3. Mole weight: 316.43.
Polyamideamine epichlorohydrin resin
Polyamideamine epichlorohydrin resin is a crosslinked heteropolymer with cationic charges, which is widely used as a wet strength agent in the paper-making process. Synonyms: polyamideamine-epichlorohydrin (PAE) resin; PAE resin.