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Polybia-MP1
Polybia-MP1 is a mastoparan-related antimicrobial insect venom peptide that selectively inhibits the proliferation of prostate and bladder cancer cells. Synonyms: H-Ile-Asp-Trp-Lys-Lys-Leu-Leu-Asp-Ala-Ala-Lys-Gln-Ile-Leu-NH2; L-isoleucyl-L-alpha-aspartyl-L-tryptophyl-L-lysyl-L-lysyl-L-leucyl-L-leucyl-L-alpha-aspartyl-L-alanyl-L-alanyl-L-lysyl-L-glutaminyl-L-isoleucyl-L-leucinamide. Grades: ≥95%. CAS No. 872043-01-1. Molecular formula: C78H132N20O19. Mole weight: 1654.03.
Polyethylene glycol loxenatide
Polyethylene glycol loxenatide is a long-acting glucagon-like peptide-1 receptor agonist for type 2 diabetes mellitus (T2DM). Synonyms: PEX168.
Polyketomycin
Polyketomycin is a tetracyclic quinone glycoside antibiotic isolated from Streptomyces sp. or Streptomyces diastatochromogenes. Polyketomycin inhibits growth of Gram-positive bacteria, and its MIC values is less than 0.2 μg/mL. Polyketomycin has antibacterial, anticancer, antimalarial activities. Synonyms: (2E,4S,4aR,12aS)-4-[[(2S,5S,6R)-5-[[2,6-Dideoxy-4-O-(2-hydroxy-3,6-dimethylbenzoyl)-3-C-methyl-α-L-xylo-hexopyranosyl]oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-4a,12a-dihydro-4a,11,12a-trihydroxy-2-(1-hydroxyethylidene)-8-methoxy-6-methyl-1,3,7,10,12(2H,4H,5H)-naphthacenepentone. Grades: >98.0%. CAS No. 200625-47-4. Molecular formula: C44H48O18. Mole weight: 864.84.
Polymyxin B nonapeptide acetate
Polymyxin B nonapeptide acetate is a cationic cyclic peptide that interacts with the outer membrane of gram-negative bacteria to increase the permeability of the membrane by promoting hydrophobic diffusion. Synonyms: H-Thr-Dab-Dab-Dab-D-Phe-Leu-Dab-Dab-Thr.CH3CO2H (Disulfide bridge: Cys3-Cys9); Polymyxin B1, 1-de[N2-(6-methyl-1-oxooctyl)-L-2,4-diaminobutanoic acid]-, acetate; 2-10-Polymyxin B1 acetate. Grades: ≥95%. Molecular formula: C45H78N14O13. Mole weight: 1023.19.
Polymyxin B nonapeptide TFA
Polymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. CAS No. 2220175-42-6. Molecular formula: C53H79F15N14O21. Mole weight: 1533.25.
Polymyxin M
Polymyxin M is a cyclic peptide antibiotic produced by Bacillus polymyxa var. Ross. Synonyms: mattacin. Grades: 95%. CAS No. 6683-17-6. Molecular formula: C51H96N16O14. Mole weight: 1157.40.
Polyoxin A
Polyoxin A is a nucleoside antifungal antibiotic produced by Str. cacaor var. asoensis and Str. piomogenus. Synonyms: (S-(E))-1-(5-((2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl)amino)-1,5-dideoxy-1-(3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl)-beta-D-allofuranuronoyl)-3-ethylidene-2-azetidinecarboxylic acid. Grades: 95%. CAS No. 19396-03-3. Molecular formula: C23H32N6O14. Mole weight: 616.53.
Polyphemusin II-Derived Peptide
Polyphemusin II-Derived Peptide has the highest inhibitory activity against the T cell line-tropic HIV-1 infection through its specific binding to a chemokine receptor CXCR4 (IC50 = 0.18±0.041 nM) and the strongest inhibitory effect on the binding of an anti-CXCR4 monoclonal antibody to CXCR4 (IC50 = 2.3±0.20 nM). Synonyms: T140; H-Arg-Arg-2Nal-Cys(1)-Tyr-Arg-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys(1)-Arg-OH; L-arginyl-L-arginyl-3-(2-naphthyl)-L-alanyl-L-cysteinyl-L-tyrosyl-L-arginyl-L-lysyl-D-lysyl-L-prolyl-L-tyrosyl-L-arginyl-L-citrullyl-L-cysteinyl-L-arginine (4->13)-disulfide; L-Arginine, L-arginyl-L-arginyl-3-(2-naphthalenyl)-L-alanyl-L-cysteinyl-L-tyrosyl-L-arginyl-L-lysyl-D-lysyl-L-prolyl-L-tyrosyl-L-arginyl-N5-(aminocarbonyl)-L-ornithyl-L-cysteinyl-, cyclic(4?13)-disulfide. Grades: ≥95%. CAS No. 229030-20-0. Molecular formula: C90H141N33O18S2. Mole weight: 2037.45.
Pomalidomide-C4-NH2
Pomalidomide-C4-NH2 is a synthetic E3 ligase ligand-linker conjugate that incorporates Pomalidomide-based CRBN ligands and linkers used in PROTAC technology. Synonyms: 4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 4-[(4-Aminobutyl)amino]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione; 4-[(4-Aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 4-[(4-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-; Thalidomide-NH-C4-NH2. Grades: ≥95%. CAS No. 1957236-34-8. Molecular formula: C17H20N4O4. Mole weight: 344.37.
Pomalidomide-PEG1-C2-NH2
Pomalidomide-PEG1-C2-NH2 is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Synonyms: Thalidomide-NH-PEG1-NH2; 4-((2-(2-aminoethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 4-{[2-(2-Aminoethoxy)ethyl]amino}-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 4-[[2-(2-aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-. Grades: ≥95%. CAS No. 2138439-12-8. Molecular formula: C17H20N4O5. Mole weight: 360.36.
Pomalidomide-PEG2-C2-NH2
Pomalidomide-PEG2-C2-NH2 is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Synonyms: Thalidomide-NH-PEG2-NH2; 4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 4-({2-[2-(2-Aminoethoxy)ethoxy]ethyl}amino)-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 4-[[2-[2-(2-aminoethoxy)ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-; 4-({2-[2-(2-aminoethoxy)ethoxy]ethyl}amino)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione; Thalidomide-NH-PEG2-C2-NH2. Grades: ≥95%. CAS No. 2093416-32-9. Molecular formula: C19H24N4O6. Mole weight: 404.42.
Porantherine
It is a polycyclic alkaloid obtained from the shrub Poranthera corymbosa. Synonyms: (1R,6aS)-3aβ,4,5,6,7,8,9,9a-Octahydro-9aβ-methyl-1H-1,6a-ethanopyrido[2,1,6-de]quinolizine; (1S, 4R, 7S, 9R)-9-Methyl-8-azatetracyclo[5.5.3.01, 8.04, 9]pentadec-5-ene; (1R,3aS,6aS,9aR)-3a,4,5,6,7,8,9,9a-octahydro-9a-methyl-1H-1,6a-ethanopyrido[2,1,6-de]quinolizine. Grades: ≥95% by HPLC. CAS No. 33529-61-2. Molecular formula: C15H23N. Mole weight: 217.35.
Porcine dynorphin A (1-13) acetate
Porcine dynorphin A(1-13) acetate is an endogenous opioid peptide that preferentially activates κ opioid receptors. Synonyms: Dynorphin A Porcine Fragment 1-13 acetate; Dynorphin A (1-13) acetate; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH.CH3CO2H; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysine acetic acid; Dynorphin A (swine), 14-de-L-tryptophan-15-de-L-aspartic acid-16-de-L-asparagine-17-de-L-glutamine-, acetate (salt); Dynorphin A (pig), 14-de-L-tryptophan-15-de-L-aspartic acid-16-de-L-asparagine-17-de-L-glutamine-, acetate (salt); 1-13-Dynorphin A (swine) acetate. Grades: ≥95%. Molecular formula: C77H130N24O17. Mole weight: 1664.00.
Porfiromycin
Porfiromycin is a quinone antibiotic produced by Str. ardus NRRL 2817. It has anti-Gram-positive and negative bacteria activity. It can inhibit sarcoma-180, Ehrlich ascites carcinoma, L-1210, H leukemia (solid type). The dose of inhibiting KB cell protein synthesis is 0.5 μg/mL. It is a bioreductive DNA alkylating agent that preferentially kills hypoxic tumor cells relative to other aerobic counterparts. Synonyms: N-Methylmitomycin C; NSC-56410; U-14743; Methylmitomycin; Methyl mitomycin C; Regamycin; Mitiromycin D; Porphyromycin; (1aS, 8S, 8aR, 8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: >98%. CAS No. 801-52-5. Molecular formula: C16H20N4O5. Mole weight: 348.35.
pp60 c-src (521-533) (phosphorylated)
pp60 c-src (521-533) (phosphorylated), the pp60 c-src carboxy-terminal phosphoregulatory peptide phosphorylated at Tyr527, participates in the regulation of kinase activity through binding intramolecularly or intermolecularly to the SH2 domain of the pp60 c-src protein. Synonyms: H-Thr-Ser-Thr-Glu-Pro-Gln-Tyr(PO3H2)-Gln-Pro-Gly-Glu-Asn-Leu-OH; L-threonyl-L-seryl-L-threonyl-L-alpha-glutamyl-L-prolyl-L-glutaminyl-O4-phosphono-L-tyrosyl-L-glutaminyl-L-prolyl-glycyl-L-alpha-glutamyl-L-asparagyl-L-leucine; L-Leucine, L-threonyl-L-seryl-L-threonyl-L-a-glutamyl-L-prolyl-L-glutaminyl-O-phosphono-L-tyrosyl-L-glutaminyl-L-prolylglycyl-L-a-glutamyl-L-asparaginyl-; Thr-Ser-Thr-Glu-Pro-Gln-O-Phosphono-Tyr-Gln-Pro-Gly-Glu-Asn-Leu-OH. Grades: >99%. CAS No. 149299-77-4. Molecular formula: C62H95N16O28P. Mole weight: 1543.48.
Praesorediosic acid
Praesorediosic acid is an aliphatic acid from the lichen parmotrema praesorediosum. Synonyms: ACMC-20mtl9; 2-Furanpentadecanoic acid, 3-carboxy-2,5-dihydro-4-methyl-5-oxo-, (2R)-. CAS No. 130342-70-0. Molecular formula: C21H34O6. Mole weight: 382.49.
Pranlukast
Pranlukast is a selective cysteinyl leukotriene receptor antagonist. Pranlukast has an anti-inflammatory effect on bronchial eosinophilic infiltration. Pranlukast is now widely used in the treatment of asthma. Uses: Leukotriene antagonists. Synonyms: Pranlukast; Ono-1078; ONO 1078; ONO-1078; ONO-RS 411; ONO-RS-411; SB 205312. Grades: >98%. CAS No. 103177-37-3. Molecular formula: C27H23N5O4. Mole weight: 481.5.
Prednisolone Hemisuccinate
Prednisolone hemisuccinate is a metabolite of a derivative of cortisol called Prednisolone. It can be used to treat a variety of inflammatory and auto-immune conditions. Synonyms: (11β)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxy-pregna-1,4-diene-3,20-dione; Prednisolone 21-O-β-carbonylpropionic Acid; Prednisolone 21-hemisuccinate; Prednisolone 21-succinate; Prednisolone Bisuccinate; Prednisolone Succinate; Prednisolut; Δ1-Hydrocortisone 21-hemisuccinate. CAS No. 2920-86-7. Molecular formula: C25H32O8. Mole weight: 460.52.
pre-doxercalciferol
Pre-doxercalciferol is a precursor of doxercalciferol, a drug used for the treatment of secondary hyperparathyroidism and metabolic bone disease. CAS No. 1818286-63-3. Molecular formula: C28H44O2. Mole weight: 412.658.
Riteau et al. used rabbit antiserum to perform immunofluorescence analysis on the Prepro-Killer Cell Immunoglobulin-Like Receptor 3DL3 (23-31) corresponding to the N-terminal sequence of KIR2DL4. It did not differ between the p49 and KIR2DL4 receptor. Synonyms: KIR3DL3 (23-31) (human); H-Val-Gly-Gly-Gln-Asp-Lys-Pro-Phe-Leu-OH. Grades: ≥95%. Molecular formula: C44H69N11O13. Mole weight: 960.09.
Prepro VIP (111-122), human acetate
Prepro VIP (111-122), human acetate is the 111-122 amino acid fragment of prepro-vasoactive intestinal polypeptide (VIP). VIP is present in the peripheral and central nervous system as a non-adrenergic, non-cholinergic neurotransmitter or neuromodulator. Synonyms: H-Val-Ser-Ser-Asn-Ile-Ser-Glu-Asp-Pro-Val-Pro-Val-OH.CH3CO2H; L-Valine, N-[1-[N-[1-[N-[N-[N-[N-[N2-[N-(N-L-valyl-L-seryl)-L-seryl]-L-asparaginyl]-L-isoleucyl]-L-seryl]-L-α-glutamyl]-L-α-aspartyl]-L-prolyl]-L-valyl]-L-prolyl]-, acetate salt (1:1); L-Valyl-L-seryl-L-seryl-L-asparaginyl-L-isoleucyl-L-seryl-L-α-glutamyl-L-α-aspartyl-L-prolyl-L-valyl-L-prolyl-L-valine acetate salt. Grades: ≥95%. CAS No. 2918768-00-8. Molecular formula: C53H87N13O21.C2H4O2. Mole weight: 1302.39.
Prepro-von Willebrand factor (641-650) (bovine)
Prepro-von Willebrand factor (641-650) (bovine), derived from the von Willebrand factor, has an increased affinity for collagen and promotes wound healing. It binds bovine collagen type I with an apparent Kd of 100 μM. Synonyms: pp-vWF (641-650); H-Trp-Arg-Glu-Pro-Ser-Phe-Cys-Ala-Leu-Ser-OH; L-Serine, L-tryptophyl-L-arginyl-L-α-glutamyl-L-prolyl-L-seryl-L-phenylalanyl-L-cysteinyl-L-alanyl-L-leucyl-. Grades: ≥95%. CAS No. 143470-36-4. Molecular formula: C54H78N14O15S. Mole weight: 1195.35.
Preptin (rat)
Preptin, a 34-amino acid peptide hormone, is co-secreted with insulin in β-cells of the pancreas in response to glucose stimulation. Preptin is osteogenic both in vitro and in vivo and may act synergistically with other β-cell hormones insulin and amylin to stimulate bone formation in hyperinsulinemic states such as obesity. Synonyms: H-Asp-Val-Ser-Thr-Ser-Gln-Ala-Val-Leu-Pro-Asp-Asp-Phe-Pro-Arg-Tyr-Pro-Val-Gly-Lys-Phe-Phe-Lys-Phe-Asp-Thr-Trp-Arg-Gln-Ser-Ala-Gly-Arg-Leu-OH; L-alpha-aspartyl-L-valyl-L-seryl-L-threonyl-L-seryl-L-glutaminyl-L-alanyl-L-valyl-L-leucyl-L-prolyl-L-alpha-aspartyl-L-alpha-aspartyl-L-phenylalanyl-L-prolyl-L-arginyl-L-tyrosyl-L-prolyl-L-valyl-glycyl-L-lysyl-L-phenylalanyl-L-phenylalanyl-L-lysyl-L-phenylalanyl-L-alpha-aspartyl-L-threonyl-L-tryptophyl-L-arginyl-L-glutaminyl-L-seryl-L-alanyl-glycyl-L-arginyl-L-leucine. Grades: ≥95%. CAS No. 315197-73-0. Molecular formula: C181H268N48O51. Mole weight: 3932.41.
Prion Protein (106-126) (human) (scrambled) is a scrambled sequence of human prion protein (106-126), which is an important control for studying the biological activity of prion protein peptides. According to circular dichroism analysis, the scrambled PrP 106-126 shows a random coil structure without aggregation, and is completely degraded after incubation with proteinase K and pronase for 30 minutes at 37°C. Synonyms: H-Asn-Gly-Ala-Lys-Ala-Leu-Met-Gly-Gly-His-Gly-Ala-Thr-Lys-Val-Met-Val-Gly-Ala-Ala-Ala-OH; L-asparagyl-glycyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-methionyl-glycyl-glycyl-L-histidyl-glycyl-L-alanyl-L-threonyl-L-lysyl-L-valyl-L-methionyl-L-valyl-glycyl-L-alanyl-L-alanyl-L-alanine; Prion Protein Fragment 106-126 Scrambled Human; PrP (106-126) (human) (scrambled). Grades: ≥90%. CAS No. 150469-23-1. Molecular formula: C80H138N26O24S2. Mole weight: 1912.24.
(Pro3)-Gastric Inhibitory Polypeptide (human)
(Pro3)-Gastric Inhibitory Polypeptide (human) is an antagonist of GIP. Synonyms: (Pro3)-GIP (human); H-Tyr-Ala-Pro-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH; L-tyrosyl-L-alanyl-L-prolyl-glycyl-L-threonyl-L-phenylalanyl-L-isoleucyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-isoleucyl-L-alanyl-L-methionyl-L-alpha-aspartyl-L-lysyl-L-isoleucyl-L-histidyl-L-glutaminyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-asparagyl-L-tryptophyl-L-leucyl-L-leucyl-L-alanyl-L-glutaminyl-L-lysyl-glycyl-L-lysyl-L-lysyl-L-asparagyl-L-alpha-aspartyl-L-tryptophyl-L-lysyl-L-histidyl-L-asparagyl-L-isoleucyl-L-threonyl-L-glutamine. Grades: ≥95%. CAS No. 299898-52-5. Molecular formula: C226H338N60O64S. Mole weight: 4951.60.
(Pro8)-Oxytocin
(Pro8)-Oxytocin is the L8P variant of oxytocin produced by the Cebidae family of New World monkeys. Its intranasal application, binding to OT and AVP V1 receptors, enhances parental behavior in rats. Synonyms: (Pro8)-Vasotocin; H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Pro-Gly-NH2 (Disulfide bridge: Cys1-Cys6). CAS No. 24327-19-3. Molecular formula: C42H62N12O12S2. Mole weight: 991.15.
Proadrenomedullin (1-20) (rat)
Synonyms: PAMP (rat); H-Ala-Arg-Leu-Asp-Thr-Ser-Ser-Gln-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2; L-Alanyl-L-arginyl-L-leucyl-L-α-aspartyl-L-threonyl-L-seryl-L-seryl-L-glutaminyl-L-phenylalanyl-L-arginyl-L-lysyl-L-lysyl-L-tryptophyl-L-asparaginyl-L-lysyl-L-tryptophyl-L-alanyl-L-leucyl-L-seryl-L-argininamide. Grades: ≥95% by HPLC. CAS No. 167699-60-7. Molecular formula: C111H177N37O28. Mole weight: 2477.82.
Pro-Asp TFA
Pro-Asp TFA can down-regulate skin inflammation in mouse skin. Synonyms: H-Pro-Asp-OH.TFA; L-Prolyl-L-aspartic acid trifluoroacetic acid; PD TFA. Grades: ≥95%. CAS No. 2260917-56-2. Molecular formula: C9H14N2O5.C2HF3O2. Mole weight: 344.24.
Procathepsin B (26-50) (rat)
Procathepsin B (26-50) (rat) is completely resistant to proteolysis by cathepsin B even after incubation overnight. It inhibits human cathepsin B with a Ki of 2.8 μM and rat cathepsin B with a Ki of 2 μM. Synonyms: H-Ala-Gly-Arg-Asn-Phe-Tyr-Asn-Val-Asp-Ile-Ser-Tyr-Leu-Lys-Lys-Leu-Cys-Gly-Thr-Val-Leu-Gly-Gly-Pro-Lys-NH2; L-alanyl-glycyl-L-arginyl-L-asparagyl-L-phenylalanyl-L-tyrosyl-L-asparagyl-L-valyl-L-alpha-aspartyl-L-isoleucyl-L-seryl-L-tyrosyl-L-leucyl-L-lysyl-L-lysyl-L-leucyl-L-cysteinyl-glycyl-L-threonyl-L-valyl-L-leucyl-glycyl-glycyl-L-prolyl-L-lysinamide. Grades: ≥95%. CAS No. 317331-27-4. Molecular formula: C123H198N34O33S. Mole weight: 2713.16.
Procollagen Type I (212-216)
Pentapeptide-4 is a matrikine used in anti-wrinkle cosmetics. Synonyms: Pentapeptide-4; L-Serine, L-lysyl-L-threonyl-L-threonyl-L-lysyl-; Lys-Thr-Thr-Lys-Ser. CAS No. 149128-48-3. Molecular formula: C23H45N7O9. Mole weight: 563.65.
Prokineticin 2 Isoform 2 (human)
Prokineticin 2 is one of the first neuropeptides to directly transmit circadian rhythm signaling to other central nervous system structures, and thus may be a key output molecule for regulating biorhythms. It has a strong ability to inhibit nocturnal locomotor activity and transmits the behavioral circadian rhythm of the suprachiasmatic nucleus. It binds to G-protein-coupled receptor PKR2, and effectively inhibits food intake. Synonyms: Bv8; PK2; H-Ala-Val-Ile-Thr-Gly-Ala-Cys-Asp-Lys-Asp-Ser-Gln-Cys-Gly-Gly-Gly-Met-Cys-Cys-Ala-Val-Ser-Ile-Trp-Val-Lys-Ser-Ile-Arg-Ile-Cys-Thr-Pro-Met-Gly-Lys-Leu-Gly-Asp-Ser-Cys-His-Pro-Leu-Thr-Arg-Lys-Val-Pro-Phe-Phe-Gly-Arg-Arg-Met-His-His-Thr-Cys-Pro-Cys-Leu-Pro-Gly-Leu-Ala-Cys-Leu-Arg-Thr-Ser-Phe-Asn-Arg-Phe-Ile-Cys-Leu-Ala-Gln-Lys-OH (Disulfide bonds, air oxidized). Grades: ≥95%. CAS No. 423206-00-2. Molecular formula: C379H606N114O101S13. Mole weight: 8792.55.
Prolamins are the main components of gluten, which contribute to gluten cohesiveness, extensibility and storage. They are rich in proline and glutamine, making them insoluble in water and difficult to digest in the gastrointestinal tract. Partial digestion produces peptide sequences that trigger an immune response in patients with celiac disease and gluten sensitivity. This short sequence of Prolamin, corresponding to the Gln and Pro-rich fraction, is involved in celiac disease. Synonyms: Alpha/beta-Gliadin A-I (wheat) (31-49); H-Leu-Gly-Gln-Gln-Gln-Pro-Phe-Pro-Pro-Gln-Gln-Pro-Tyr-Pro-Gln-Pro-Gln-Pro-Phe-OH. Grades: ≥95%. CAS No. 137832-02-1. Molecular formula: C105H148N26O28. Mole weight: 2222.46.
Prolyl-Threonine is a dipeptide composed of proline and threonine. Synonyms: prolylthreonine; Pro-Thr; PT dipeptide; P-T Dipeptide. CAS No. 129024-38-0. Molecular formula: C9H16N2O4. Mole weight: 216.23.
Pro-Lys
Prolyl-lysine is a dipeptide composed of proline and lysine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Prolyl-L-lysine; Prolyl-Lysine. Grades: 95%. CAS No. 71227-70-8. Molecular formula: C11H21N3O3. Mole weight: 243.30.
Promothiocin A
Promothiocin A is an antibiotic produced by Str.lividans. The minimum induction concentration of Promothiocin A for tipA promoter is 0.2 μg/mL. Synonyms: Alaninamide, L-valyl-2-(aminomethyl)-5-methyl-4-oxazolecarbonyl-2-((1S)-1-aminoethyl)-4-thiazolecarbonyl-6-(2-((1S)-1-aminoethyl)-5-methyl-4-oxazolyl)-5-(4-carboxy-2-thiazolyl)-2-pyridinecarbonyl-2,3-didehydro-, (4->1)-lactam. Grades: >98%. CAS No. 156737-05-2. Molecular formula: C36H37N11O8S2. Mole weight: 815.88.
Promothiocin B
Promothiocin B is an antibiotic produced by Str.lividans. The minimum induction concentration of Promothiocin B for tipA promoter is 0.1 μg/mL. CAS No. 156737-06-3. Molecular formula: C42H43N13O10S2. Mole weight: 954.00.
Cas No. 105608-41-1. Molecular formula: C23H34O6. Mole weight: 406.51.
Pro-Phe-Arg-7-amido-4-methylcoumarin
PFR-AMC is a highly sensitive, fluorogenic substrate for plasma as well as pancreatic and urinary kallikreins. Synonyms: PFR-NMec. CAS No. 65147-21-9. Molecular formula: C30H37N7O5. Mole weight: 575.66.
Propionyl famciclovir
An impurity of Famciclovir. Famciclovir is used for the treatment of various herpesvirus infections, most commonly for herpes zoster. Synonyms: O-Desacetyl O-Propionyl Famciclovir; 2-(Acetoxymethyl)-4-(2-amino-9H-purin-9-yl)butyl Propionate. Grades: > 95%. Molecular formula: C15H21N5O4. Mole weight: 335.37.
An impurity of Ropinirole.Ropinirole acts as a D2, D3, and D4 dopamine receptor agonist with highest affinity for D2. It is weakly active at the 5-HT2, and α2 receptors and is said to have virtually no affinity for the 5-HT1, GABA, mAChRs, α1, and β-adrenoreceptors. Grades: > 95%. Molecular formula: C19H28N2O HCl. Mole weight: 336.91.
Propylthiouracil
Propylthiouracil is a thyroperoxidase and 5'-deiodinase inhibitor. It is a thiouracil-derived drug used to treat hyperthyroidism (including Graves' disease) by decreasing the amount of thyroid hormone produced by the thyroid gland. Besides, propylthiouracil inhibits the enzyme thyroperoxidase, which normally acts in thyroid hormone synthesis by oxidizing the anion iodide (I-) to iodine (I0), facilitating iodine's addition to tyrosine residues on the hormone precursor thyroglobulin. But propylthiouracil does not inhibit the action of the sodium-dependent iodide transporter located on follicular cells' basolateral membranes. Uses: Antimetabolites, antithyroid agents. Synonyms: 6-n-Propylthiouracil; 6-Propyl-2-thiouracil; PTU. Grades: >98%. CAS No. 51-52-5. Molecular formula: C7H10N2OS. Mole weight: 170.23.
Prosaptide TX14(A) acetate
Prosaptide TX14(A) acetate is a potent agonist of G protein-coupled receptors GPR37 and GPR37L1 (EC50 values are 7 and 5 nM, respectively). Prosaptide Tx 14(A) is the active fragment of prosaposin, a secreted neuroprotective and glioprotective factor. It increases both ERK1 and ERK2 phosphorylation in Schwann cells. Synonyms: L-Threonyl-D-alanyl-L-leucyl-L-isoleucyl-L-α-aspartyl-L-asparaginyl-L-asparaginyl-L-alanyl-L-threonyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-leucyl-L-tyrosine acetate; 16-29-Saposin C [2-D-alanine,8-alanine,de-11-lysine,30-tyrosine] (human) acetate; Prosaptide Tx 14(A) acetate; H-Thr-D-Ala-Leu-Ile-Asp-Asn-Asn-Ala-Thr-Glu-Glu-Ile-Leu-Tyr-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C71H114N16O28. Mole weight: 1639.76.
Pro-Ser
Pro-Ser inhibits melanin synthesis in Mel-Ab cells through down-regulation of tyrosinase. Synonyms: L-Serine, N-L-prolyl-; L-prolyl-L-serine. Grades: ≥95%. CAS No. 71835-80-8. Molecular formula: C8H14N2O4. Mole weight: 202.21.
Prosomatostatin
Somatostatin 1-28 is a somatostatin receptor agonist derived from the post-translational cleavage of prosomatostatin. Synonyms: Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys (Disulfide bridge: Cys17-Cys28); Somatostatin, pro-; ProSRIF; Somatostatin 1-28; SRIF-28; SRIF 28; SRIF28; Somatostatin 28. Grades: >98%. CAS No. 74315-46-1. Molecular formula: C137H207N41O39S3. Mole weight: 3148.55.
Protein Kinase C 19-31 acetate
Protein Kinase C 19-31 acetate is a peptide inhibitor of protein kinase C (PKC) originating in the pseudo-substrate regulatory domain of PKCA (residues 19-31). It is used as a protein kinase C substrate peptide for testing the protein kinase C activity. Synonyms: PKC (19-31) acetate; H-Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val-OH.CH3CO2H; L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysyl-glycyl-L-alanyl-L-leucyl-L-arginyl-L-glutaminyl-L-lysyl-L-asparagyl-L-valine acetic acid. Grades: ≥95%. Molecular formula: C69H122N26O18. Mole weight: 1603.90.
Protein Kinase C Peptide Substrate acetate
Protein Kinase C Peptide Substrate acetate targets specific cell compartments and activates G protein-coupled receptors, tyrosine kinase receptors, or tyrosine kinase-coupled receptors by relying on second messenger and specific adaptor proteins in response to extracellular signals. It regulates a variety of physiological functions, including nervous, endocrine, exocrine, inflammatory, and immune system activation. Synonyms: L-α-Glutamyl-L-arginyl-L-methionyl-L-arginyl-L-prolyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminylglycyl-L-seryl-L-valyl-L-arginyl-L-arginyl-L-arginyl-L-valine acetate; H-Glu-Arg-Met-Arg-Pro-Arg-Lys-Arg-Gln-Gly-Ser-Val-Arg-Arg-Arg-Val-OH acetate. Grades: ≥95%. Molecular formula: C85H159N39O23S. Mole weight: 2127.52.
Protein LMWP
LMWP can be used as a cell-penetrating peptide (CPP) to achieve efficient intracellular protein or gene delivery in the clinic. Synonyms: Low Molecular Weight Protamine; H-Val-Ser-Arg-Arg-Arg-Arg-Arg-Arg-Gly-Gly-Arg-Arg-Arg-Arg-OH; L-Arginine, L-valyl-L-seryl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginylglycylglycyl-L-arginyl-L-arginyl-L-arginyl-. Grades: ≥95%. CAS No. 121052-30-0. Molecular formula: C72H142N44O16. Mole weight: 1880.18.
PSA1 (141-150) is a prostate-specific antigen 1 peptide used for immunotherapy in cancer trials. Molecular formula: C57H97N13O15S. Mole weight: 1236.52.
Pseudin-2
Pseudin-2, a cationic α-helical peptide originally isolated from paradoxical frog skin, has antimicrobial activity based on the Pseudis paradox. It stimulates insulin secretion in Brin-BD11 cells through a Ca2+-independent mechanism. Synonyms: H-Gly-Leu-Asn-Ala-Leu-Lys-Lys-Val-Phe-Gln-Gly-Ile-His-Glu-Ala-Ile-Lys-Leu-Ile-Asn-Asn-His-Val-Gln-OH; glycyl-L-leucyl-L-asparagyl-L-alanyl-L-leucyl-L-lysyl-L-lysyl-L-valyl-L-phenylalanyl-L-glutaminyl-glycyl-L-isoleucyl-L-histidyl-L-alpha-glutamyl-L-alanyl-L-isoleucyl-L-lysyl-L-leucyl-L-isoleucyl-L-asparagyl-L-asparagyl-L-histidyl-L-valyl-L-glutamine. Grades: ≥95%. CAS No. 388602-02-6. Molecular formula: C122H202N36O32. Mole weight: 2685.17.
Pseudoalterobactin A
Pseudoalterobactin A is a siderophore produced by Pseudoalteromonas sp.KP20-R. It has a strong affinity for iron ions. Molecular formula: C41H63N11O21S. Mole weight: 1078.06.
Pseudoalterobactin B
Pseudoalterobactin B is a siderophore produced by Pseudoalteromonas sp.KP20-R. It has a strong affinity for iron ions. Molecular formula: C41H63N13O21S. Mole weight: 1106.08.
Pseudomonic acid E
Pseudomonic acid E is an impurity of Mupirocin, which is a carboxylic acid bacteriostatic/bactericidal antibiotic. Synonyms: Mupirocin III; Mupirocin Impurity 2. CAS No. 167842-57-1. Molecular formula: C28H48O9. Mole weight: 528.67.
Pteridic acid A
Pteridic acid A is a plant growth promoter produced by Streptomyces hygrescopicus TP-A0451. It has Auxin-like plant growth hormone activity, and 1 nmol/L can promote the growth of legumes and other plant roots. Molecular formula: C21H32O5. Mole weight: 364.47.
Pteridic acid B
Pteridic acid B is a plant growth promoter produced by Streptomyces hygrescopicus TP-A0451. It has Auxin-like plant growth hormone activity, and 1 nmol/L can promote the growth of legumes and other plant roots. Molecular formula: C21H32O5. Mole weight: 364.47.
Pterulone
Pterulone is a Coenzyme I: Coenzyme Q oxidoreductase inhibitor produced by Pterula sp. 82168. It has anti-yeast and filamentous fungus effect. Synonyms: (E)-Pterulone; Pterulone A. Grades: 95%. CAS No. 190143-31-8. Molecular formula: C13H11ClO2. Mole weight: 234.68.
pTH (1-31) (human)
pTH (1-31) stimulates adenylyl cyclase in ROS 17/2 rat osteosarcoma cells as strongly as pTH (1-34) (teriparatide). Synonyms: H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-OH. CAS No. 157938-23-3. Molecular formula: C162H269N49O47S2. Mole weight: 3719.29.
PTH (13-34) (HUMAN)
Synonyms: Parathyroid Hormone Fragment 13-34 human; Parathyroid Hormone (13-34), human; LYS-HIS-LEU-ASN-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE. CAS No. 81306-64-1. Molecular formula: C125H199N39O33S. Mole weight: 2808.22.
pTH (1-34) amide (human)
pTH (1-34) amide (human) is a compound synthetic peptide hormone is acts as an agonist to the parathyroid hormone receptor. It is employed for the research of osteoporosis, hypoparathyroidism and various bone-related disorders. Synonyms: H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-NH2; Parathyroid hormone (1-34)amide; L-seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparagyl-L-leucyl-glycyl-L-lysyl-L-histidyl-L-leucyl-L-asparagyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparagyl-L-phenylalaninamide; hPTH (1-34)-NH2; human parathyroid hormone (1-34) amide. Grades: 95%. CAS No. 83139-29-1. Molecular formula: C181H292N56O50S2. Mole weight: 4116.79.
pTH (1-37) (human)
pTH (1-37) (human) is a native bioactive fragment of pTH (1-84) (human) in circulation. Pulsatile rather than continuous administration of pTH (1-37) (human) can increase growth, bone calcium content and bone mineral density in uremic animals. Synonyms: Parathyrin (1-37) (human); H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-Val-Ala-Leu-OH; L-seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparagyl-L-leucyl-glycyl-L-lysyl-L-histidyl-L-leucyl-L-asparagyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparagyl-L-phenylalanyl-L-valyl-L-alanyl-L-leucine. Grades: 95%. CAS No. 136799-54-7. Molecular formula: C195H316N58O54S2. Mole weight: 4401.15.
pTH (2-34) (human) is an impurity and potential metabolite of teriparatide produced during chemical synthesis. The N-terminal truncation sequence of pTH (2-34) has a reduced potency in stimulating bone formation. Like pTH (1-34), pTH (2-34) reduced coronary perfusion pressure in isolated rat hearts, but had no effect on heart rate compared with pTH(1-34). Synonyms: H-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH; Human PTH (2-34); hpTH (2-34). Grades: ≥95%. CAS No. 247902-18-7. Molecular formula: C178H286N54O49S2. Mole weight: 4030.70.