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Ropinirole Impurity 1
An impurity of Ropinirole.Ropinirole acts as a D2, D3, and D4 dopamine receptor agonist with highest affinity for D2. It is weakly active at the 5-HT2, and α2 receptors and is said to have virtually no affinity for the 5-HT1, GABA, mAChRs, α1, and β-adrenoreceptors. Synonyms: 2-[2-(Dipropylamino)ethyl]-6-nitro-α-oxo-benzenepropanoic Acid Ethyl Ester. Grades: > 95%. CAS No. 91374-24-2. Molecular formula: C19H28N2O5. Mole weight: 364.45.
Ropinirole Isohexyl Analog
An impurity of Ropinirole.Ropinirole acts as a D2, D3, and D4 dopamine receptor agonist with highest affinity for D2. It is weakly active at the 5-HT2, and α2 receptors and is said to have virtually no affinity for the 5-HT1, GABA, mAChRs, α1, and β-adrenoreceptors. Grades: > 95%. Molecular formula: C16H24N2O. Mole weight: 260.38.
Ropinirole N-Oxide
An impurity of Ropinirole.Ropinirole acts as a D2, D3, and D4 dopamine receptor agonist with highest affinity for D2. It is weakly active at the 5-HT2, and α2 receptors and is said to have virtually no affinity for the 5-HT1, GABA, mAChRs, α1, and β-adrenoreceptors. Synonyms: 1,3-Dihydro-4-[2-(oxidodipropylamino)ethyl]-2H-indol-2-one. Grades: > 95%. CAS No. 1076199-41-1. Molecular formula: C16H24N2O2. Mole weight: 276.38.
(R)-Ornidazole
An impurity of Ornidazole, which is a 12-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria. Uses: Radiation-sensitizing agents. Synonyms: αR-(Chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol. Grades: > 95%. Molecular formula: C7H10ClN3O3. Mole weight: 219.63.
Roxithromycin
Roxithromycin is a semi-synthetic macrolide antibiotic that inhibits bacterial cell growth and replication. It is used to treat respiratory tract, urinary and soft tissue infections. Synonyms: Roxithromycinum; RU 28965; RU-28965; RU-965; RU965; Rulide; (9E)-9-[O-[(2-Methoxyethoxy)methyl]oxime] Erythromycin; Assoral; Brilid; Claramid; Forilin; Overal; Rossitrol; Rotramin; Roxeptin; Roxid; Roxithromycin A; Surlid. Grades: >98%. CAS No. 80214-83-1. Molecular formula: C41H76N2O15. Mole weight: 837.05.
(R)-Oxybutynin HCl
An impurity of Oxybutynin which is an antagonist of M1, M2, & M3 muscarinic acetylcholine receptors used to treat symptoms of overactive bladder. Synonyms: (R)-Oxybutynin; (R)-OXYBUTYNIN HCL; (R)-OXYBUTYNIN CHLORIDE; (R)-OXYBUTYNIN HYDROCHLORIDE; (R)-Hydroxycyclohexylphenylacetic acid 4-(diethylamino)-2-butynyl ester; (R)-CYCLOHEXYL-HYDROXY-PHENYL-ACETIC ACID 4-DIETHYLAMINO-BUT-2-YNYL ESTER; (αS)-α-Cyclohexyl-α-hydroxybenzeneacetic acid 4-(diethylamino)-2-butin-1-yl ester; Benzeneacetic acid, a-cyclohexyl-a-hydroxy-, 4-(diethylamino)-2-butynyl ester, (R)-; (R)-α-Phenylcyclohexaneglycolic Acid 4-(Diethylamino)-2-butynyl Ester, Hydrochloride. Grades: > 95%. CAS No. 119618-21-2. Molecular formula: C22H31NO3.HCl. Mole weight: 393.96.
(R)-Pantoprazole
An impurity of Pantoprazole which is a prescription drug used as a short-term treatment for gastroesophageal reflux disease (GERD). Synonyms: 5-(Difluoromethoxy)-2-[(R)-[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole; (+)-5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole; (+)-Pantoprazole; R-Pantoprazole; (R)-(+)-Pantoprazole. Grades: > 95%. CAS No. 142706-18-1. Molecular formula: C16H15F2N3O4S. Mole weight: 383.38.
(R)-Rabeprazole Sodium Salt
R enantiomer of Rabeprazole Sodium Salt. Rabeprazole is proton pump inhibitor as an antiulcer drug. Synonyms: 2-[(R)-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole Sodium Salt; R-(+)-Rabeprazole Sodium Salt. Grades: > 95%. CAS No. 171440-18-9. Molecular formula: C18H23N3O3S. Na. Mole weight: 384.47.
(R,R)-Palonosetron Acid
(R,R)-Palonosetron Acid is an impurity of Palonosetron, which is a potent, single stereoisomeric 5-HT3 receptor antagonist developed to prevent chemotherapy-induced nausea and vomiting. Synonyms: (8R)-8-((quinuclidin-3-ylamino)methyl)-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid. Molecular formula: C19H26N2O2. Mole weight: 314.42.
RS09 2TFA
RS09 2TFA, a TLR4 agonist, is an adjuvant that promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. RS09 increases antibody production in the vaccine environment. Synonyms: H-Ala-Pro-Pro-His-Ala-Leu-Ser-OH.2TFA; L-alanyl-L-prolyl-L-prolyl-L-histidyl-L-alanyl-L-leucyl-L-serine trifluoroacetic acid; RS 09 2TFA. Grades: ≥95%. Molecular formula: C35H51F6N9O13. Mole weight: 919.82.
(R)-Shikonin is a naphthoquinone extracted from Lithospermum erythrorhizon and Alkanna sp. It is a natural cardioprotective, antioxidative and anti-inflammatory agent. Synonyms: Shikonin; Isoarnebin 4; Tokyo Violet; Shikonin S; (R)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthalenedione; R-5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-pentenyl]-1,4-naphthalenedione; (+)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone; (+)-Shikonin; (R)-(+)-Shikonin; NSC 252844; Shikonine; Tokyo Violet. Grades: ≥98%. CAS No. 517-89-5. Molecular formula: C16H16O5. Mole weight: 288.30.
(R/S)-Methotrexate N,N-dimethylamide
(R/S)-Methotrexate N,N-dimethylamide is one of methotrexate impurities. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Molecular formula: C22H27N9O4. Mole weight: 481.51.
(R,S)-Palonosetron Acid
(R,S)-Palonosetron Acid is an impurity of Palonosetron, which is a potent, single stereoisomeric 5-HT3 receptor antagonist developed to prevent chemotherapy-induced nausea and vomiting. Synonyms: (R)-8-((((1S,3R,4S)-quinuclidin-3-yl)amino)methyl)-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid. Molecular formula: C19H26N2O2. Mole weight: 314.42.
(R,S,S,S)-Orlistat
An isomeric impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: N-Formyl-D-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester; [2S-[2α(R*),3β]]-N-Formyl-D-leucine 1-[(3-Hexyl-4-oxo-2-oxetanyl)methyl]dodecyl Ester. Grades: > 95%. CAS No. 104872-28-8. Molecular formula: C29H53NO5. Mole weight: 495.75.
A pigment hs more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity. Synonyms: Furo[3,2-g]isoquinoline-2,9(7H,9aH)-dione, 9a-methyl-3-(1-oxohexyl)-6-(1-propenyl)-, [R-(E)]-; Furo[3,2-g]isoquinoline-2,9(7H,9aH)-dione, 9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propenyl-, (9aR)- (9CI). Grades: > 95%. CAS No. 514-66-9. Molecular formula: C21H23NO4. Mole weight: 353.42.
Rubropunctatin
A pigment hs more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity. Synonyms: 2H-Furo[3,?2-g]?[2]?benzopyran-2,?9(9aH)?-dione, 9a-methyl-3-(1-oxohexyl)?-6-(1E)?-1-propen-1-yl-, (9aR)?-. Grades: > 95%. CAS No. 514-67-0. Molecular formula: C21H22O5. Mole weight: 354.41.
Rufinamide
Rufinamide (E 2080; CGP 33101; RUF 331) is a new antiepileptic agent that differs structurally from other antiepileptic drugs and is approved as adjunctive therapy for Lennox-Gastaut syndrome (LGS). Uses: Anticonvulsants. Synonyms: CGP-33101; CGP 33101; CGP33101; E 2080; RUF 331; Inovelon; Banzel; E2080; RUF331; E-2080; RUF-331. Grades: 0.99. CAS No. 106308-44-5. Molecular formula: C10H8F2N4O. Mole weight: 238.19.
Rumbrin is a cytoprotective substance produced by Auxarthron umbrinumn 13. Synonyms: 6-(8-(3-Chloro-1H-pyrrol-2-yl)-1-methyl-1,3,5,7-octatetraenyl)-4-methoxy-3-methyl-2H-pyran-2-one. Grades: >98%. CAS No. 148528-19-2. Molecular formula: C20H20ClNO3. Mole weight: 357.83.
RVD-Hpα acetate
RVD-Hpα acetate is a neuropeptide that acts as a selective CB1 receptor agonist. It has been demonstrated to increase the phosphorylation of ERK1/2 levels or release of intracellular Ca2+. It is also a high-affinity CB2 positive allosteric modulator (Ki = 50 nM). Synonyms: H-Arg-Val-Asp-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His-OH.CH3CO2H; L-arginyl-L-valyl-L-alpha-aspartyl-L-prolyl-L-valyl-L-asparagyl-L-phenylalanyl-L-lysyl-L-leucyl-L-leucyl-L-seryl-L-histidine. Grades: ≥95%. Molecular formula: C67H109N19O19. Mole weight: 1484.71.
RVG-9R
RVG-9R, a chimeric rabies virus glycoprotein fragment, binds and transduces siRNA in vitro into neuronal cells, resulting in highly efficient gene silencing. Repeated administration of RVG-9R-bound siRNA did not induce inflammatory cytokines or anti-peptide antibodies. Synonyms: Rabies Virus Glycoprotein (194-221) Nonaarginine Chimer; H-Tyr-Thr-Ile-Trp-Met-Pro-Glu-Asn-Pro-Arg-Pro-Gly-Thr-Pro-Cys-Asp-Ile-Phe-Thr-Asn-Ser-Arg-Gly-Lys-Arg-Ala-Ser-Asn-Gly-Gly-Gly-Gly-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH. Grades: ≥95%. CAS No. 1678417-57-6. Molecular formula: C201H334N82O55S2. Mole weight: 4843.51.
An intermediate of Carfilzomib, which is a second-generation proteasome inhibitor for the treatment of relapsed and refractory multiple myeloma. Synonyms: 1-Pentanone, 2-amino-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-, (2S)-, 2,2,2-trifluoroacetate (1:1); 1-Pentanone, 2-amino-4-methyl-1-[(2R)-2-methyloxiranyl]-, (2S)-, trifluoroacetate; (2R)-2-[(2S)-2-Amino-4-methylpentanoyl]-2-methyloxirane trifluoroacetate; (2S)-2-Amino-4-methyl-1-[(2R)-2-methyloxiranyl]-1-pentanone Trifluoroacetate; (2S)-2-Amino-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-1-pentanone 2,2,2-Trifluoroacetate. Grades: ≥95%. CAS No. 247068-85-5. Molecular formula: C9H17NO2.C2HF3O2. Mole weight: 285.26.
(S)-3-Amino-2-piperidone hydrochloride
Ornithine-1,5-Lactam HCl, is an building block , used in the synthesis of various pharmaceutical compounds. Synonyms: (3S)-3-aminopiperidin-2-one;hydrochloride. Grades: 96 %. CAS No. 42538-31-8. Molecular formula: C5H11ClN2O. Mole weight: 150.61.
(S)-4-Acetamido-5-hydroxypentanoic acid
Molecular formula: C7H13NO4. Mole weight: 175.2.
(S)-4-Benzamido-5-hydroxypentanoic acid
Cas No. 1053648-94-4. Molecular formula: C12H15NO4. Mole weight: 237.3.
(S)-4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione is a key intermediate in the synthesis of Exatecan, Irinotecan and Camptothecin analogs. Synonyms: (4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione; (S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione; 1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-ethyl-7,8-dihydro-4-hydroxy-, (4S)-. Grades: ≥95%. CAS No. 110351-94-5. Molecular formula: C13H13NO5. Mole weight: 263.25.
(S)-4-Hydroxy Mephenytoin
The S-enantiomer metabolite of Mephenytoin which is used as an anticonvulsant. Synonyms: (S)-4-Hydroxy Mephenytoin; 82695-93-0; (5S)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylimidazolidine-2,4-dione; 4'-hydroxymephenytoin; SCHEMBL14067600; DTXSID20654509; CHEBI:196007; (S)-5-Ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione; 5S)-5-Ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione. Grades: > 95%. CAS No. 82695-93-0. Molecular formula: C12H14N2O3. Mole weight: 234.26.
(S)-a-Benzylmalic acid
(S)-a-Benzylmalic acid is produced by the strain of Penicillum sp. It can be used to inhibit carboxylpeptidase A and slightly inhibit carboxylpeptidase B. Synonyms: (s)-a-benzylmalic acid; (S)-2-Benzyl-2-hydroxybutanedioic acid. CAS No. 51692-93-4. Molecular formula: C11H12O5. Mole weight: 224.21.
Sakamototide substrate peptide acetate
Sakamototide substrate peptide acetate is a substrate peptide of a member of the kinase AMPK family and is used for the determination of kinase activity. Synonyms: H-Ala-Leu-Asn-Arg-Thr-Ser-Ser-Asp-Ser-Ala-Leu-His-Arg-Arg-Arg-OH.CH3CO2H; L-alanyl-L-leucyl-L-asparagyl-L-arginyl-L-threonyl-L-seryl-L-seryl-L-alpha-aspartyl-L-seryl-L-alanyl-L-leucyl-L-histidyl-L-arginyl-L-arginyl-L-arginine acetic acid. Grades: ≥95%. CAS No. 2703746-19-2. Molecular formula: C71H126N30O25. Mole weight: 1799.97.
Salicylamide
Hydrochlorothiazide Related Compound is a non-prescription drug with analgesic and antipyretic properties. It is used in combination with both aspirin and caffeine in the over-the-counter pain remedy "PainAid". Synonyms: 2-hydroxybenzamide. Grades: > 95 %. CAS No. 65-45-2. Molecular formula: C7H7NO2. Mole weight: 137.14.
Salinomycin Sodium
Salinomycin Sodium is an antibiotic produced by the strain of Str. albus 80614. It has anti-gram-positive bacteria and mycobacterium effects. It also has the effect against gram-negative bacteria and fungi but the effect is weak. It has a therapeutic effect on chickens infected with coccidiococci. It can be used to prevent chicken coccidiosis. Synonyms: Salinomycin sodium salt; Sodium salinomycin; Procoxacin sodium salt; Coxistac sodium salt; Bio-Cox sodium salt; Sacox sodium salt; Salinomicina sodium salt. Grades: >98%. CAS No. 55721-31-8. Molecular formula: C42H69NaO11. Mole weight: 772.99.
Salmine is a protamine obtained from the sperm of salmon and used chiefly in the form of its sulfate to reverse the anticoagulant effect of heparin or as the protamine component of protamine zinc insulin. CAS No. 9014-82-8.
Santin is a flavonoid compound found in Alnus japonica and Grindelia glutinosa. It has anti-inflammatory activity and inhibits cyclo-oxygenase and 5-lipoxygenase pathways of arachidonic metabolism. Synonyms: 2-(4-Methoxyphenyl)-5,7-dihydroxy-3,6-dimethoxy-4H-1-benzopyran-4-one; 3,4',6-Trimethoxy-5,7-dihydroxyflavone; 5,7-Dihydroxy-3,6,4'-trimethoxyflavone; 6-Hydroxykaempferol 3,4',6-trimethyl ether; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3,6-dimethoxy-2-(4-methoxyphenyl)-; Centauridin; 3-Methylbetuletol. Grades: ≥95%. CAS No. 27782-63-4. Molecular formula: C18H16O7. Mole weight: 344.32.
Saquayamycin A1
It is produced by the strain of Str. nodosus MH190-16F3. It has antimicrobial effect, but it has weaker effect against gram-negative bacteria. It has inhibitory effect on leukemia P388 cells and adriamycin-resistant P388 cells. Synonyms: Benz[a]anthracene-1,7,12(2H)-trione, 9-[2,6-dideoxy-4-O-[(2R,6S)-5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl]- -Darabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3,4a,8,12b-tetrahydroxy-3-methyl-, (3R,4aR,12bS)-; (3R)-9-[4-O-[(2R,6S)-5,6-Dihydro-6-methyl-5-oxo-2H-pyran-2-yl]-2,6-dideoxy-β-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3α,4aα,8,12bα-tetrahydroxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione. Grades: 95%. CAS No. 99260-66-9. Molecular formula: C31H32O12. Mole weight: 596.58.
(Sar1)-Angiotensin II
(Sar1)-Angiotensin II is a specific agonist of angiotensin AT1 receptor. It binds to brain membrane-rich particles, with a Kd of 2.7 nM. (Sar1)-Angiotensin II can stimulate protein synthesis and cell growth in embryonic chick myocytes. Synonyms: 1-Sar-5-ile-angiotensin II; Angiotensin II, sarcosyl(1)-isoleucine(5)-. CAS No. 51833-69-3. Molecular formula: C49H71N13O10. Mole weight: 1002.17.
(Sar1)-Angiotensin II acetate
(Sar1)-Angiotensin II acetate is a specific agonist of the angiotensin AT1 receptor that binds to brain membrane-rich particles, with a Kd of 2.7 nM. (Sar1)-Angiotensin II acetate can stimulate protein synthesis and cell growth in embryonic chick myocytes. Synonyms: H-Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-OH.CH3CO2H; sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine acetic acid. Grades: ≥95%. CAS No. 2863657-02-5. Molecular formula: C51H75N13O12. Mole weight: 1062.22.
SAR441255
SAR441255 is a synthetic peptide agonist of the GLP-1, GCG, and GIP receptors. SAR441255 showed substantial body weight loss and improved glucose control in diabetic obese monkeys. Synonyms: H-Aib-HGTFTSDLSKL-K(γGlu-γGlu-Palm acid)-EEQRQ-AibEFIEWLKA-dAla-GPPS-Aib-KPPPK-NH2. Molecular formula: C206H323N51O66. Mole weight: 4570.06.
[Sar9] Substance P acetate
[Sar9]-Substance P acetate is a potent and selective neurokinin (NK)-1 receptor agonist. The effect of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP. Synonyms: Substance P, 9-(N-methylglycine)-, acetate (1:1); 9-(N-Methylglycine)substance P acetate; [MeGly9]-substance P acetate; H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met-NH2.CH3CO2H; L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanyl-sarcosyl-L-leucyl-L-methioninamide acetate. Grades: ≥95%. Molecular formula: C66H104N18O15S. Mole weight: 1421.71.
Scensidin is a new depsidone isolated from the lichen Buellia canescens. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 2,7-dichloro-3,8-dimethoxy-1,6-dimethyl-; 2,8-dichloro-3,9-dimethoxy-1,7-dimethylbenzo[b][1,4]benzodioxepin-6-one. CAS No. 86190-23-0. Molecular formula: C17H14Cl2O5. Mole weight: 369.20.
It is produced by the strain of Scytalidium sp. 36-93. Synonyms: 10H-Naphtho[2,3-c]pyran-10-one,1,3,4,4a,5,10a-hexahydro-5,9-dihydroxy-3,7-dimethoxy-3-methyl-, (3R,4aS,5S,10aR)-rel-(+)-. CAS No. 208183-20-4. Molecular formula: C16H20O6. Mole weight: 308.33.
Scytalol C
It is produced by the strain of Scytalidium sp. 36-93. Synonyms: Naphtho[1,2-b]furan-5(4H)-one,2,3,3a,9btetrahydro-6-hydroxy-2,8-dimethoxy-4-(methoxymethylene)-2-methyl-, (2R,3aR,4E,9bR)-rel-(-)-. CAS No. 208183-22-6. Molecular formula: C17H20O6. Mole weight: 320.34.
(S)-Desmethyl Rabeprazole Sodium Salt
S enantiomer of Desmethyl Rabeprazole Sodium Salt. Desmethyl Rabeprazole Sodium Salt is a derivative of Rabeprazole. Rabeprazole is proton pump inhibitor as an antiulcer drug. Grades: > 95%. Molecular formula: C17H18N3O3S.Na. Mole weight: 367.41.
SDF-1α (human)
SDF-1α (human) is a synthetic peptide containing a 1:50 ratio of BSA (low levels of endotoxins) and is a multifunctional cytokine signaling through CXCR4. SDF-1α is involved in many pathological conditions such as rheumatoid arthritis, pulmonary fibrosis, metastasis and leukemia cell progression. Internalization of SDF-1α dependence of CXCR4 HIV coreceptor contributes to inhibition of HIV replication. Synonyms: Stromal Cell-Derived Factor-1α (human); H-Lys-Pro-Val-Ser-Leu-Ser-Tyr-Arg-Cys-Pro-Cys-Arg-Phe-Phe-Glu-Ser-His-Val-Ala-Arg-Ala-Asn-Val-Lys-His-Leu-Lys-Ile-Leu-Asn-Thr-Pro-Asn-Cys-Ala-Leu-Gln-Ile-Val-Ala-Arg-Leu-Lys-Asn-Asn-Asn-Arg-Gln-Val-Cys-Ile-Asp-Pro-Lys-Leu-Lys-Trp-Ile-Gln-Glu-Tyr-Leu-Glu-Lys-Ala-Leu-Asn-Lys-OH (Disulfide bridge: Cys9-Cys34, Cys11-Cys50). Grades: ≥95%. CAS No. 1268129-65-2. Molecular formula: C356H578N106O93S4. Mole weight: 7959.43.
(S)-Dihydroaeruginoic acid
It is a simple aromatic siderophore produced by several species of pseudomonas. It exhibits antibacterial, antifungal and antitumor activity. Synonyms: (4S)-4,5-Dihydro-2-(2-hydroxyphenyl)-4-thiazolecarboxylic Acid; CGP 52547; (S)-4,5-Dihydro-2-(2-hydroxyphenyl)-4-thiazolecarboxylic Acid; (+)-(S)-Dihydroaeruginoic Acid; (+)-Dihydroaeruginoic acid; 4-Thiazolecarboxylic acid, 4,5-dihydro-2-(2-hydroxyphenyl)-, (S)-; 4-Thiazolecarboxylic acid, 4,5-dihydro-2-(2-hydroxyphenyl)-, (4S)-; (S)-2-(2-Hydroxyphenyl)-4,5-dihydrothiazole-4-carboxylic acid; (4S)-Dihydroaeruginoic acid. Grades: >98% by HPLC. CAS No. 143209-04-5. Molecular formula: C10H9NO3S. Mole weight: 223.25.
(S, E) -2- (3- (1- ( (tert-Butyldimethylsilyl) oxy) -3- (2- (1- ( (tert-butyldimethylsilyl) oxy) vinyl) phenyl) propyl) styryl) -7-chloroquinoline is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Molecular formula: C40H52ClN2Si2. Mole weight: 652.48.
Seco Rapamycin (sodium salt)
Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin which is a natural macrolide immunosuppressant. Seco-rapamycin inhibits the ChT-L (D) and PGPH (E) peptidases, and activate the T-L (F) peptidase and poorly activates mTOR. IC50: ChT-L. Uses: A decomposition product of rapamycin (r124000). Synonyms: sodium;(2S)-1-[2-[(2R,3R,6S)-2-hydroxy-6-[(2S,9S,11R,13R,14R,17R,21R)-14-hydroxy-22-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15,19-pentaenyl]-3-methyloxan-2-yl]-2-oxoacetyl]piperidine-2-c. Grades: > 95%. CAS No. 148554-65-8. Molecular formula: C51H78NNaO13. Mole weight: 936.15.
Secretoneurin, rat acetate
Secretoneurin, rat acetate, a 33-amino acid polypeptide, is a neuropeptide generated in brain, adrenal medulla and other endocrine tissues by proteolytic processing of secretogranin II (chromogranin C). The endogenous peptide can enhance dopamine release. Synonyms: L-Threonyl-L-asparaginyl-L-α-glutamyl-L-isoleucyl-L-valyl-L-α-glutamyl-L-α-glutamyl-L-glutaminyl-L-tyrosyl-L-threonyl-L-prolyl-L-glutaminyl-L-seryl-L-leucyl-L-alanyl-L-threonyl-L-leucyl-L-α-glutamyl-L-seryl-L-valyl-L-phenylalanyl-L-glutaminyl-L-α-glutamyl-L-leucylglycyl-L-lysyl-L-leucyl-L-threonylglycyl-L-prolyl-L-seryl-L-asparaginyl-L-glutamine acetate; Secretoneurin (mouse) acetate; H-Thr-Asn-Glu-Ile-Val-Glu-Glu-Gln-Tyr-Thr-Pro-Gln-Ser-Leu-Ala-Thr-Leu-Glu-Ser-Val-Phe-Gln-Glu-Leu-Gly-Lys-Leu-Thr-Gly-Pro-Asn-Ser-Gln-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C161H256N40O60. Mole weight: 3712.04.