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Pemetrexed Impurity B
An impurity of Pemetrexed which is a chemotherapy drug. Synonyms: Pemetrexed (5R)-Dimer ; (2S)-2,2'-[[(5R)-2,2'-Diamino-4,4',6-trioxo-1,4,4',6,7,7'-hexahydro-1'H,5H-5,6'-bipyrrolo[2,3-d]pyrimidine-5,5'-diyl]bis(ethane-2,1-diylbenzene-4,1-diylcarbonylimino)]-dipentanedioic acid. Grades: > 95%. Molecular formula: C40H40N10O13. Mole weight: 868.82.
Pemetrexed Impurity C
An impurity of Pemetrexed which is a chemotherapy drug used to treat non small cell lung cancer and pleural mesothelioma. Synonyms: Pemetrexed (5S)-Dimer ; (2S)-2,2'-[[(5S)-2,2'-Diamino-4,4',6-trioxo-1,4,4',6,7,7'-hexahydro-1'H,5H-5,6'-bipyrrolo[2,3-d]pyrimidine-5,5'-diyl]bis(ethane-2,1-diylbenzene-4,1-diylcarbonylimino)]-dipentanedioic acid. Grades: > 95%. Molecular formula: C40H40N10O13. Mole weight: 868.82.
Pemetrexed Impurity-R
An impurity of Pemetrexed which belongs to a class of chemotherapeutic drugs known as folate antimetabolites. Grades: > 95%. Molecular formula: C20H21N5O7. Mole weight: 443.42.
Pemetrexed Impurity-S
An impurity of Pemetrexed which is used to treat mesothelioma in combination with another chemotherapy drug called cisplatin. Grades: > 95%. Molecular formula: C20H21N5O7. Mole weight: 443.42.
Pemetrexed L-glutamic acid benzyl dimethyl triester is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-γ-glutamyl-L-glutamic Acid Benzyl Dimethyl Triester. Molecular formula: C34H38N6O9. Mole weight: 674.70.
Pemetrexed L-Glutamic Acid Trisodium
An impurity of Pemetrexed which is a chemotherapy drug. Synonyms: Pemetrexed L-Glutamic Acid Trisodium Salt; N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-γ-glutamyl-L-glutamic Acid Sodium Salt; Pemetrexed Impurity D. Grades: > 95%. CAS No. 1265908-59-5. Molecular formula: C25H25N6O9.3Na. Mole weight: 622.48.
Pemetrexed Methyl Ester
An impurity of Pemetrexed which is a chemotherapy drug used to treat non small cell lung cancer and pleural mesothelioma. Synonyms: Pemetrexed Methyl Ester; N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid 1,5-Dimethyl Ester. Grades: > 95%. CAS No. 155405-81-5. Molecular formula: C22H25N5O6. Mole weight: 455.47.
Pemetrexed Monomethyl Ester Impurity 1
An impurity of Pemetrexed which is used as a single agent or in combination with other chemotherapeutic agents for the treatment of several types of cancer. Synonyms: sodium (4R)-4-{[4-(2-{2-amino-4-oxo-1H,4H,7H- pyrrolo[2,3-d]pyrimidin-5- yl}ethyl)phenyl]formamido}-5-methoxy-5- oxopentanoate. Grades: > 95%. CAS No. 1265908-61-9. Molecular formula: C21H22N5O6.Na. Mole weight: 463.43.
Pemetrexed Monomethyl Ester Impurity 2
An impurity of Pemetrexed which is an antifolate, a substance that blocks the activity of folic acid. Synonyms: Pemetrexed Monomethyl Ester 2; 1265908-60-8; (2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]-5-methoxy-5-oxopentanoic acid; SCHEMBL15078817; (S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanoic acid ; Pemetrexed Impurity 2; 1265908-64-2. Grades: > 95%. CAS No. 1265908-60-8. Molecular formula: C21H22N5O6.Na. Mole weight: 463.43.
Pemetrexed ph Euro impurity B + C Mixture (1:1)
Pemetrexed Related Impurity 1
An impurity of Pemetrexed which is used as a single agent or in combination with other chemotherapeutic agents for the treatment of several types of cancer. Grades: > 95%. Molecular formula: C25H28N6O9. Mole weight: 556.54.
Pemetrexed Related Impurity 2
An impurity of Pemetrexed which is an antifolate, a substance that blocks the activity of folic acid. Grades: > 95%. Molecular formula: C20H21N5O8. Mole weight: 459.42.
Pemetrexed Tromethamine Amide
Pemetrexed tromethamine amide is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (S)-tert-Butyl 2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-((1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)amino)-5-oxopentanoate. Molecular formula: C28H38N6O8. Mole weight: 586.64.
Penaldic Acid
Penaldic Acid is an impurity of Penicillin. Penicillin belongs to the β-lactam class of antibiotics, is a very common antibacterial drug. Molecular formula: C11H11NO4. Mole weight: 221.21.
Penazaphilone F
Penazaphilone F is an azaphilone alkaloid originally isolated from the solid fermented rice culture of Penicillium sclerotiorum cib-411. CAS No. 2334467-48-8. Molecular formula: C26H32ClNO6. Mole weight: 489.99.
Penazaphilone H
Penazaphilone H is an azaphilone alkaloid originally isolated from the solid fermented rice culture of Penicillium sclerotiorum cib-411. CAS No. 2334467-50-2. Molecular formula: C23H28ClNO5. Mole weight: 433.92.
Penazaphilone I
Penazaphilone I is an azaphilone alkaloid originally isolated from the solid fermented rice culture of Penicillium sclerotiorum cib-411. CAS No. 2334467-51-3. Molecular formula: C25H30ClNO6. Mole weight: 475.96.
Penbutolol
Penbutolol is a sympathomimetic drug used to treat mild to moderate high blood pressure by binding to both beta-1 adrenergic receptors and beta-2 adrenergic receptors. Synonyms: 1-(2-Cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-2-propanol; 1-(tert-Butylamino)-3-(o-cyclopentylphenoxy)-2-propanol; (±)-Isopenbutolol; rac Penbutolol. Grades: > 95%. CAS No. 36507-48-9. Molecular formula: C18H29NO2. Mole weight: 291.44.
Penbutolol hydrochloride
Penbutolol hydrochloride is a salt form of Penbutolol. Penbutolol is a beta blocker used in the treatment of hypertension. It binds to both beta-1 adrenergic receptors and beta-2 adrenergic receptors. Synonyms: 1-tert-Butylamino-3-(2-cyclopentylphenoxy)-propan-2-ol hydrochloride. CAS No. 28163-36-2. Molecular formula: C18H30ClNO2. Mole weight: 327.893.
Penciclovir
Penciclovir is a guanosine analogue antiviral drug used for the treatment of various herpesvirusinfections. It is a nucleoside analogue which exhibits low toxicity and good selectivity. Uses: Antiviral agents; reverse transcriptase inhibitors. Synonyms: BRL-39123; BRL 39123; BRL39123; VSA 671; VSA671; VSA-671; Penciclovir; Denavir, Vectavir and Fenivir. Grades: >98%. CAS No. 39809-25-1. Molecular formula: C10H15N5O3. Mole weight: 253.26.
Penehyclidine HCl (Mixture of Isomers)
An impurity of Penehyclidine which is a cholinergic receptor antagonist and NF-kappa B inhibitor. Synonyms: Penequine hydrochloride; 151937-76-7; Penehyclidine hydrochloride; Penehyclidine (hydrochloride); 1-Cyclopentyl-1-phenyl-2-(quinuclidin-3-yloxy)ethanol hydrochloride; 0P1E1UF04I; 2-(1-azabicyclo[2.2.2]octan-3-yloxy)-1-cyclopentyl-1-phenylethanol; hydrochloride;Benzenemethanol, alpha-((1-azabicyclo(2.2.2)oct-3-yloxy)methyl)-alpha-cyclopentyl-, hydrochloride. Grades: > 95%. CAS No. 151937-76-7. Molecular formula: C20H29NO2.HCl. Mole weight: 351.92.
Penehyclidine Impurity 1
An impurity of Penehyclidine which is a new anticholinergic agent which selectively block M1 and M3, but not M2 receptors. Grades: > 95%. Molecular formula: C27H30O4S2. Mole weight: 482.67.
Penehyclidine Impurity 10
An impurity of Penehyclidine which is a selective M1 and M3 receptor antagonist with neuroprotection activity in cerebral ischemia. Grades: > 95%. Molecular formula: C20H29NO2. Mole weight: 315.46.
Penehyclidine Impurity 11
An impurity of Penehyclidine which is a cholinergic receptor antagonist and NF-kappa B inhibitor. Grades: > 95%. Molecular formula: C13H16O. Mole weight: 188.27.
Penehyclidine Impurity 2
An impurity of Penehyclidine which is a new anticholinergic agent which selectively block M1 and M3, but not M2 receptors. Grades: > 95%. Molecular formula: C20H24O3S. Mole weight: 344.48.
Penehyclidine Impurity 3
An impurity of Penehyclidine which is a selective M1 and M3 receptor antagonist with neuroprotection activity in cerebral ischemia. Grades: > 95%. Molecular formula: C20H29NO2. Mole weight: 315.46.
Penehyclidine Impurity 4
An impurity of Penehyclidine which is a cholinergic receptor antagonist and NF-kappa B inhibitor. Grades: > 95%. Molecular formula: C12H21NO. Mole weight: 195.31.
Penehyclidine Impurity 5
An impurity of Penehyclidine which is a cholinergic receptor antagonist with neuroprotection activity in cerebral ischemia. Grades: > 95%. Molecular formula: C12H16O2S. Mole weight: 224.32.
Penehyclidine Impurity 6 (Mixture of Diastereomers)
An impurity of Penehyclidine which is a cholinergic receptor antagonist with neuroprotection activity in cerebral ischemia. Grades: > 95%. Molecular formula: C33H45NO3. Mole weight: 503.73.
Penehyclidine Impurity 7
An impurity of Penehyclidine which is a new anticholinergic agent which selectively block M1 and M3, but not M2 receptors. Grades: > 95%. Molecular formula: C20H29NO2. Mole weight: 315.46.
Penehyclidine Impurity 8
An impurity of Penehyclidine which is a new anticholinergic agent which selectively block M1 and M3, but not M2 receptors. Grades: > 95%. Molecular formula: C20H29NO2. Mole weight: 315.46.
Penehyclidine Impurity 9
An impurity of Penehyclidine which is a selective M1 and M3 receptor antagonist with neuroprotection activity in cerebral ischemia. Grades: > 95%. Molecular formula: C20H29NO2. Mole weight: 315.46.
Penicillenic Acid Disulfide is an impurity of Penicillin. Penicillin belongs to the β-lactam class of antibiotics, is a very common antibacterial drug. CAS No. 21291-06-5. Molecular formula: C32H34N4O8S2. Mole weight: 666.76.
Penicillin F Potassium Salt
An impurity of Penicillin Potassium which which shows bactericidal property by acting directly on peptidoglycans. Synonyms: (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(1-oxo-3-hexen-1-yl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Potassium Salt; 2-Pentenylpenicillin Potassium Salt; Penicillin I Potassium Salt; 6-(3-Hexenamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Potassium Salt. Grades: 95%. CAS No. 97299-13-3. Molecular formula: C14H19N2O4S.K. Mole weight: 350.47.
Penicillin G Clemizol
An impurity of Penicillin G which is used to treat many different types of infections caused by bacteria, such as ear infections. Synonyms: Clemizole penicillin; 6011-39-8; Clemizolpenicillin; 5UL276H6TF; Benzylpenicillin combined with 1-p-chlorobenzyl-2-(1-pyrrolidinylmethyl)benzimidazole; Penicillinclemizolum; 1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole; (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Clemizole Penicillin G; Antihistamin-Penicillin-G; UNII-5UL276H6TF; Neopenyl; Clemizole penicillin [INN:BAN]; Clemizol-penicilina [INN-Spanish]; Clemizole penicilline [INN-French]; Clemizolum penicillinum [INN-Latin]; Clemizol-penicillin grunenthal; DTXSID10975533; CLEMIZOLE PENICILLIN [MART.]; CLEMIZOLE PENICILLIN [WHO-DD]; Q27123267; 6-[(1-Hydroxy-2-phenylethylidene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid--1-[(4-chlorophenyl)methyl]-2-[(pyrrolidin-1-yl)methyl]-1H-benzimidazole (1/1). Grades: > 95%. CAS No. 6011-39-8. Molecular formula: C19H20ClN3.C16H18N2O4S. Mole weight: 325.84 334.40.
Penicillin G potassium
Cas No. 113-98-4.
Penicillin G Procaine
An impurity of Penicillin G which is an antibacterial drug (intravenous use) against a wide range of bacteria. Uses: Anti-bacterial agents. Synonyms: Procaine Penicillin G Hydrate; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid compd. with 2-(Diethylamino)ethyl 4-Aminobenzoate Hydrate; p-Aminohydratebenzoic Acid 2-(Diethylamino)ethyl Ester Mono[3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate] Monohydrate; Benzylpenicillin Procaine Monohydrate. Grades: > 95%. CAS No. 6130-64-9. Molecular formula: C16H18N2O4S. C13H20N2O2. Mole weight: 570.72.
Penicillin Impurity 1
Penicillin Impurity 1 is an impurity of Penicillin. Penicillin belongs to the β-lactam class of antibiotics, is a very common antibacterial drug. Synonyms: (4S)-2t-((R)-amino-carboxy-methyl)-5,5-dimethyl-thiazolidine-4r-carboxylic acid. CAS No. 37727-80-3. Molecular formula: C8H14N2O4S. Mole weight: 234.27.
Penicillin Impurity 2
Penicillin Impurity 2 is an impurity of Penicillin. Penicillin belongs to the β-lactam class of antibiotics, is a very common antibacterial drug. Synonyms: 6-APA Dimer. Grades: 98%. CAS No. 1978372-79-0. Molecular formula: C16H24N4O6S2. Mole weight: 432.51.
Penicillin Impurity 3
Penicillin Impurity 3 is an impurity of Penicillin. Penicillin belongs to the β-lactam class of antibiotics, is a very common antibacterial drug. Synonyms: 6α-chloropenicillanic acid 1,1-dioxide. CAS No. 76350-36-2. Molecular formula: C8H10ClNO5S. Mole weight: 267.69.
Penicillin V
An impurity of Penicillin V which is used to treat many different types of infections caused by bacteria, such as ear infections (use by mouth). Uses: Penicillins. Synonyms: penicillin v; Phenoxymethylpenicillin; Penicillin phenoxymethyl; Oracillin; 87-08-1; Phenopenicillin; Phenomycilline; V-Cillin; Vebecillin; Fenospen; Distaquaine V; Phenoxymethyl penicillin; Meropenin; Calcipen; Fenacilin; Phenocillin; Phenoxymethylenepenicillinic acid; Stabicillin; Apopen; Oratren; Rocilin; Ospen;6beta-Phenoxyacetamido-2,2-dimethylpenam-3alpha-carboxylic acid; Phenoxymethylpenicillin, Antibiotic for Culture Media Use Only; Penicillin V, United States Pharmacopeia (USP) Reference Standard; Phenoxymethylpenicillin, European Pharmacopoeia (EP) Reference Standard; 4-THIA-1-AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, 3,3-DIMETHYL-7-OXO-6-((PHENOXYACETYL)AMINO)-, (2S-(2ALPHA,5ALPHA,6.BETA)).-. Grades: > 95%. CAS No. 87-08-1. Molecular formula: C16H18N2O5S. Mole weight: 350.4.
Penicolinate B
Penicolinate B is a fungal metabolite found in Penicillium and it has diverse biological activities. It is active against M. tuberculosis (MIC = 25 μg/ml), as well as P. falciparum, B. cereus, and C. albicans (IC50s = 1.4, 25, and 3.67 μg/ml, respectively). Penicolinate B is also cytotoxic to MCF-7, KB, NCI H187, and Vero cells (IC50s = 6.21, 17.78, 0.307, and 2.79 μg/ml, respectively). Synonyms: Penicolinate A monomethyl ester. Grades: >95% by HPLC. CAS No. 1418291-70-9. Molecular formula: C23H30N2O4. Mole weight: 398.49.
Penilloaldehyde
Penilloaldehyde is an impurity of Penicillin. Penicillin belongs to the β-lactam class of antibiotics, is a very common antibacterial drug. Synonyms: Benzylpenilloaldehyde; G-penilloaldehyde; phenylacetylaminoacetaldehyde; Phenyl-essigsaeure-(2-oxo-aethylamid); phenyl-acetic acid-(2-oxo-ethylamide). CAS No. 5663-61-6. Molecular formula: C10H11NO2. Mole weight: 177.20.
Penipurdin A
Penipurdin A is an anthraquinone fungal metabolite produced by the strain of P. purpurogenum and it has antibacterial activity. It is active against M. tuberculosis with a MIC value of 25 μg/ml. Synonyms: 1,6-dihydroxy-3-[(2S)-2-hydroxypropyl]-8-methoxy-9,10-anthracenedione. Grades: ≥95%. CAS No. 1821668-16-9. Molecular formula: C18H16O6. Mole weight: 328.32.
Pentalenic acid
Pentalenic acid is a sesquiterpenoid originally isolated from S. avermitilis. It is a precursor in the biosynthesis of the antibiotic pentalenolactone. Synonyms: 69394-19-0; 9-Hydroxy-2,10,10-trimethyltricyclo[6.3.0.01,5]undec-6-ene-6-carboxylic acid; BS-1324MCULE-6511007969; NCGC00381256-01. Grades: >95% by HPLC. CAS No. 69394-19-0. Molecular formula: C15H22O3. Mole weight: 250.33.
Penta-O-acetylgluconyl Chloride
Penta-O-acetylgluconyl chloride is one of chlorhexidine impurities. Chlorhexidine is a disinfectant and topical anti-infective agent for reduction of pocket depth in patients with adult periodontitis. Synonyms: D-Gluconoyl Chloride 2,3,4,5,6-Pentaacetate; D-Gluconoyl Chloride Pentaacetate; 2,3,4,5,6-Penta-O-acetyl-D-glucosyl Chloride; 2,3,4,5,6-Pentaacetyl-D-gluconic Chloride; Gluconoyl Chloride Pentaacetate; Pentaacetylgluconoyl Chloride; D-gluco-2,3,4,5,6-Pentaacetoxy-hexanyl chloride. CAS No. 53555-69-4. Molecular formula: C16H21ClO11. Mole weight: 424.78.
Pentoxifylline
Pentoxifylline is a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF and leukotriene synthesis, and reduces inflammation and innate immunity. It improves red blood cell deformability, reduces blood viscosity and decreases the potential for platelet aggregation and thrombus formation. It also reduces AST and ALT levels and may improve liver histological scores in patients with NALFD/NASH, but did not appear to affect cytokines. Uses: Free radical scavengers. Synonyms: Trental; PTX; Oxpentifylline. Grades: >98%. CAS No. 6493-5-6. Molecular formula: C13H18N4O3. Mole weight: 278.31.
Pentoxifylline EP Impurity D
An impurity of Pentoxifylline which improves red blood cell deformability, reduces blood viscosity and decreases the potential for platelet aggregation and thrombus formation. Synonyms: 1-(3-Hydroxypropyl)theobromine; 1-(3-Hydroxypropyl)-3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione; 1-(3-hydroxypropyl)-3,7-dimethylpurine-2,6-dione; 1-(3-Hydroxypropyl)-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione; KMM2BK7040; 1H-Purine-2,6-dione, 3,7-dihydro-1-(3-hydroxypropyl)-3,7-dimethyl-; gamma-Otb; 3,7-Dihydro-1-(3-hydroxypropyl)-3,7-dimethyl-1H-purine-2,6-dione; 1-(3-Hydroxypropyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione; gamma-Oxypropyltheobromin [German]; gamma-Oxypropyltheobromin; BRN 0263337; 1-(gamma-Oxypropyl)-theobromin [German]; 1-(3-Hydroxypropyl)-3,7-dimethylxanthine; 1-(gamma-Oxypropyl)-theobromin; hydroxypropyltheobromine; UNII-KMM2BK7040; 2-26-00-00271 (Beilstein Handbook Reference); SCHEMBL9293614; DTXSID60208141; Theobromine, 1-(3-hydroxypropyl)-; MFCD01682404; 3,7-Dihydro-1-(3-hydroxypropyl)-3,7-dimethyl-1H-purine-2,6-dione (9CI); AKOS000125777; PENTOXIFYLLINE IMPURITY D [EP IMPURITY]. Grades: > 95%. CAS No. 59413-14-8. Molecular formula: C10H14N4O3. Mole weight: 238.25.
Pentoxifylline EP Impurity E
An impurity of Pentoxifylline which improves red blood cell deformability, reduces blood viscosity and decreases the potential for platelet aggregation and thrombus formation. Grades: > 95%. Molecular formula: C15H16N8O4. Mole weight: 372.35.
Pentoxifylline EP Impurity G
An impurity of Pentoxifylline which reduces AST and ALT levels and may improve liver histological scores in patients with NALFD/NASH, but did not appear to affect cytokines. Synonyms: 3,7-Dihydro-3,7-dimethyl-6-[(5-oxohexyl)oxy]-2H-purin-2-one. Grades: > 95%. CAS No. 93079-86-8. Molecular formula: C13H18N4O3. Mole weight: 278.31.
Pentoxifylline EP Impurity H
An impurity of Pentoxifylline which is a competitive nonselective phosphodiesterase inhibitor and also reduces AST and ALT levels and may improve liver histological scores in patients with NALFD/NASH, but did not appear to affect cytokines. Grades: > 95%. Molecular formula: P-0510. Mole weight: 362.43.
Pentoxifylline EP Impurity I
An impurity of Pentoxifylline which improves red blood cell deformability, reduces blood viscosity and decreases the potential for platelet aggregation and thrombus formation. Synonyms: 1-Benzyltheobromine; 55247-90-0; 1-Benzyl-3,7-dimethylxanthine; 1-benzyl-3,7-dimethylpurine-2,6-dione; 8RUV41LJ96; Pentoxifylline Impurity I; UNII-8RUV41LJ96; Pentoxifylline impurity I [EP]; 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(phenylmethyl)-; 1-Benzyl-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 3,7-Dihydro-3,7-dimethyl-1-(phenylmethyl)-1H-purine-2,6-dione; AC1LEVEQ; SMR000091572; ChemDiv2_003332; Cambridge id 5356026; Oprea1_050581; Oprea1_707161; MLS000114126; CHEMBL1883787; SCHEMBL10394509; DTXSID70353474; HMS1378H10; HMS2241F19; AKOS025151071; PENTOXIFYLLINE IMPURITY I [EP IMPURITY]; AB00082638-01; 1-benzyl-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione. Grades: > 95%. CAS No. 55247-90-0. Molecular formula: C14H14N4O2. Mole weight: 270.29.
Pentoxifylline EP Impurity J
An impurity of Pentoxifylline which is a competitive nonselective phosphodiesterase inhibitor and also reduces AST and ALT levels and may improve liver histological scores in patients with NALFD/NASH, but did not appear to affect cytokines. Synonyms: 1,1'-[(5E)-5-Methyl-7-oxo-5-undecene-1,11-diyl] Bis[Theobromine]; 3,7-Dihydro-3,7-dimethyl-1-[(5E)-5-methyl-7-oxo-11-(2,3,6,7-tetrahydro-3,7-dimethyl-2,6-dioxo-1H-purin-1-yl)-5-undecen-1-yl]-1H-purine-2,6-dione; 1,1'-[(5E)-5-Methyl-7-oxo-5-undecene-1,11-diyl]bis[3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione; Pentoxifylline EP Impurity J. Grades: > 95%. CAS No. 874747-30-5. Molecular formula: C26H34N8O5. Mole weight: 538.61.
Pentoxifylline EP Impurity K
An impurity of Pentoxifylline which is a competitive nonselective phosphodiesterase inhibitor and also reduces AST and ALT levels and may improve liver histological scores in patients with NALFD/NASH, but did not appear to affect cytokines. Synonyms: Bisdionin C; 74857-22-0; WT3HN8U2ZZ; UNII-WT3HN8U2ZZ; 1-[3-(3,7-dimethyl-2,6-dioxopurin-1-yl)propyl]-3,7-dimethylpurine-2,6-dione; Pentoxifylline impurity K [EP]; 1,1'-Trimethylenedi-theobromine; 1,1'-Propane-1,3-Diylbis(3,7-Dimethyl-3,7-Dihydro-1h-Purine-2,6-Dione); 1,1-(Propane-1,3-diyl)bis(3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione); 1H-Purine-2,6-dione, 1,1'-(1,3-propanediyl)bis(3,7-dihydro-3,7-dimethyl-; BisdioninC; 2ybt; DW0; CHEMBL1738791; SCHEMBL10018600; BDBM81508; AKOS037643563; AS-16905; HY-115661; CS-0104283; PENTOXIFYLLINE IMPURITY K [EP IMPURITY]; Q27459756. Grades: > 95%. CAS No. 74857-22-0. Molecular formula: C17H20N8O4. Mole weight: 400.4.
Pentoxyverine Impurity B Citrate (Caramiphen Citrate)
An impurity of Pentoxyverine which is a potent, selective σ1 agonist and M1 antagonist (Ki values=11, 76 and 167 nM for σ1, M1 and M2 respectively). Synonyms: Caramiphen; 77-22-5; Parpanil; Pentaphen (pharmaceutical); 2-(diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate; 1-Phenylcyclopentanecarboxylic acid 2-(diethylamino)ethyl ester; 97J7NP0XJY; CYCLOPENTANECARBOXYLIC ACID, 1-PHENYL-, 2-(DIETHYLAMINO)ETHYL ESTER; CHEMBL61946; Cyclopentanecarboxylicacid, 1-phenyl-, 2-(diethylamino)ethyl ester; Parpanit; 2-(Diethylamino)ethyl 1-phenylcyclopentanecarboxylate; 2-Diethylaminoethyl 1-phenylcyclopentane-1-carboxylate; Caramifenio; Caramiphene. Grades: > 95%. CAS No. 77-22-5. Molecular formula: C18H27NO2.C6H8O7. Mole weight: 481.55.
Pentoxyverine Impurity B HCl (Caramiphen HCl)
An impurity of Pentoxyverine which is an orally active antitussive to treat cough. Synonyms: Caramiphen hydrochloride; 125-85-9; Caramiphen HCl; Parpanit; Caramiphen (hydrochloride); 2-Diethylaminoethyl 1-phenylcyclopentane-1-carboxylate hydrochloride; 1-Phenylcyclopentanecarboxylic acid 2-diethylaminoethyl ester hydrochloride; 2-(diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate; hydrochloride; 4858SN190E; Parpanil hydrochloride; Pentaphene hydrochloride; Caramiphenium chloride; Pentaphene hydrochloride; Caramiphene hydrochloride; Geigy 2747. Grades: > 95%. CAS No. 125-85-9. Molecular formula: C18H27NO2.HCl. Mole weight: 325.88.
Peramivir
Peramivir is an antiviral inhibitor with an IC50 of median 0.09 nM. It prevents the virus from infecting cells. Uses: A new antiviral agent for influenza treatment, could be used as neuraminidase inhibitor for treating human and avian influenza. Synonyms: BCX 1812; BCX1812; BCX-1812 (1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic Acid. Grades: ≥98.0%. CAS No. 330600-85-6. Molecular formula: C15H28N4O4. Mole weight: 328.41.
Peramivir Amino acid Impurity
An impurity of Peramivir which is an antiviral inhibitor. Synonyms: 4-aminocyclopent-2-ene-1-carboxylic acid. Grades: > 95%. Molecular formula: C6H9NO2. Mole weight: 127.14.
Peramivir Methyl Ester Impurity
An impurity of Peramivir which is an antiviral inhibitor, preventing viruses from infected cells with an IC50 of median 0.09 nM. Synonyms: Methyl 4-aminocyclopent-2-ene-1-carboxylate. Grades: > 95%. Molecular formula: C7H11NO2. Mole weight: 141.17.
Perhexiline
Perhexiline maleate salt is a carnitine palmitoyltransferase 1 (CPT1) and CPT2 inhibitor. It is an anti-anginal metabolic modulator and used in treatments for angina. It inhibits the mitochondrial enzyme CPT-1 and to a lesser extent CPT-2. It was also recently found to inhibit the activity of mTORC1. Uses: Calcium channel blockers. Synonyms: PERHEXILINE; 2-(2,2-Dicyclohexylethyl)piperidine; Perhexilene; 6621-47-2; (+)-2-(2,2-Dicyclohexylethyl)piperidine; Perhexilinum [INN-Latin]; Perhexilina [INN-Spanish]; Piperidine, 2-(2,2-dicyclohexylethyl)-; (-)-2-(2,2-Dicyclohexylethyl)piperidine; 39648-48-1; Perhexiline (INN); CHEMBL75880; CHEBI:35553; KU65374X44; perhexilline; Perhexilina; PERHEXILINE [INN]; Perhexiline [INN:BAN]; 10118-35-1; EINECS 229-569-5; 39648-47-0; UNII-KU65374X44; 2-[2,2-DICYCLOHEXYLETHYL]PIPERIDINE MALEATE SALT; EINECS 252-426-3; EINECS 254-558-7; EINECS 254-559-2; Piperidine, 2-(2,2-dicyclohexylethyl)-, (2Z)-2-butenedioate (1:1). Grades: > 95%. CAS No. 6621-47-2. Molecular formula: C19H35N. Mole weight: 277.5.
Perindopril acyl glucuronide
An impurity of Perindopril which has anticancer activity through the inhibition of tumor growth and angiogenesis in hepatocellular carcinoma cells. Synonyms: Perindopril Acyl-α-D-glucuronide. Grades: > 95%. Molecular formula: C25H40N2O11. Mole weight: 544.6.
Perindoprilat
Perindoprilat, the active metabolite of perindopril, is a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor in vitro with IC50 values ranging between 1.5 and 3.2 nM. Uses: Angiotensin-converting enzyme inhibitors. Synonyms: (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-Carboxybutyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic Acid; [2S-[1[R*(R*)], 2α, 3aβ, 7aβ]]-1-[2-[(1-Carboxybutyl)amino]-1- oxopropyl]octahydro-1H-indole-2-carboxylic Acid; S 9780; USP Perindopril Related Compound B. Grades: > 95%. CAS No. 95153-31-4. Molecular formula: C17H28N2O5. Mole weight: 340.42.
Perindoprilat acyl glucuronide
An impurity of Perindoprilat which is a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor in vitro with IC50 values ranging between 1.5 and 3.2 nM. Synonyms: Perindoprilat Acyl-β-D-glucuronide. Grades: > 95%. Molecular formula: C23H36N2O11. Mole weight: 516.55.
Perindoprilat Lactam A
An impurity of Perindoprilat which specifically and competitively inhibits ACE in vitro with IC50 values ranging between 1.5 and 3.2 nM. Synonyms: (αS,3S,5aS,9aS,10aS)-Decahydro-3-methyl-1,4-dioxo-α-propylpyrazino[1,2-a]indole-2(1H)-acetic Acid; [3S-[2(R*), 3α, 5aβ, 9aβ, 10aβ]]-Decahydro-3-methyl-1, 4-dioxo-α- propylpyrazino[1,2-a]indole-2(1H)-acetic Acid; 10aS-Perindoprilat Diketopiperazine; Perindopril EP Impurity C. Grades: > 95%. CAS No. 129970-99-6. Molecular formula: C17H26N2O4. Mole weight: 322.41.
Perindopril Impurity C
An impurity of Perindopril which has anticancer activity through the inhibition of tumor growth and angiogenesis in hepatocellular carcinoma cells. Synonyms: Perindoprilat Lactam A. Grades: > 95%. Molecular formula: C17H26N2O4. Mole weight: 322.41.
Perindopril Impurity D
An impurity of Perindopril which is a long-acting ACE inhibitor. Synonyms: Perindoprilat Lactam B; (αS,3S,5aS,9aS,10aR)-Decahydro-3-methyl-1,4-dioxo-α-propylpyrazino[1,2-a]indole-2(1H)-acetic Acid; [3S-[2(R*), 3α, 5aβ, 9aβ, 10aα]]-Decahydro-3-methyl-1, 4-dioxo-α- propylpyrazino[1,2-a]indole-2(1H)-acetic Acid; 10aR-Perindoprilat Diketopiperazine; USP Perindopril Related Compound D; Perindopril EP Impurity D. Grades: > 95%. CAS No. 130061-28-8. Molecular formula: C17H26N2O4. Mole weight: 322.41.
Perindopril Impurity E
An impurity of Perindopril which suppresses angiotensin II production in vitro. Synonyms: Perindoprilat Isopropyl Ester; (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-Methylethoxycarboxybutyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic Acid; Perindopril EP Impurity E. Grades: > 95%. CAS No. 1356837-89-2. Molecular formula: C20H34N2O5. Mole weight: 382.5.
Perindopril Impurity F
An impurity of Perindopril which has anticancer activity through the inhibition of tumor growth and angiogenesis in hepatocellular carcinoma cells. Synonyms: (αS,3S,5aS,9aS,10aS)-Decahydro-3-methyl-1,4-dioxo-α-propylpyrazino[1,2-a]indole-2(1H)-acetic Acid Ethyl Ester; [3S-[2(R*), 3α, 5aβ, 9aβ, 10aβ]]-Decahydro-3-methyl-1, 4 -dioxo-α-propylpyrazino[1,2-a]indole-2(1H)-acetic Acid Ethyl Ester; Perindopril Related Compound F USP; Perindopril EP Impurity F. Grades: > 95%. CAS No. 129970-98-5. Molecular formula: C19H30N2O4. Mole weight: 350.46.
Perindopril Impurity G
An impurity of Perindopril which is used to treat patients with hypertension, diabetes mellitus type 2, coronary heart disease, chronic heart failure or stable coronary artery disease in form of perindopril arginine on the basis of a large evidence. Grades: > 95%. Molecular formula: C24H37N3O5. Mole weight: 447.58.