BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| D-His-endo-Ala18-Liraglutide | D-His-endo-Ala18-Liraglutide is a derivative of Liraglutide, a long-acting analog of glucagon-like peptide-1 (GLP-1) receptor which could protect b-cells from apoptosis under conditions associated with the development of type 1 and type 2 diabetes. Synonyms: H-D-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Ala-Lys(Gamma-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C175H270N44O52. Mole weight: 3822.36. |  |
| DHMEQ racemate | DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ. Synonyms: Cis(+/-)-2-hydroxy-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)benzamide; rel-DHMEQ. CAS No. 287194-38-1. Molecular formula: C13H11NO5. Mole weight: 261.23. | |
| DHODH-IN-1 | DHODH-IN-1 is a potent Dihydroorotate Dehydrogenase (DHODH) inhibitor (IC50 = 25 nM), and also an inhibitor of pyrimidine biosynthesis pathway. Synonyms: 5-Cyclopropyl-2-[4-(2,6-difluorophenoxy)-3-isopropoxy-5-methyl-1H-pyrazol-1-yl]-3-fluoropyridine; Pyridine, 5-cyclopropyl-2-[4-(2,6-difluorophenoxy)-5-methyl-3-(1-methylethoxy)-1H-pyrazol-1-yl]-3-fluoro-; 2-[4-[2,6-bis(fluoranyl)phenoxy]-5-methyl-3-propan-2-yloxy-pyrazol-1-yl]-5-cyclopropyl-3-fluoranyl-pyridine; 2-(3-Isopropyloxy-4-(2,6-difluorophenoxy)-5-methyl-1H-pyrazole-1-yl)-3-fluoro-5-cyclopropylpyridine. Grade: ≥95%. CAS No. 1800296-63-2. Molecular formula: C21H20F3N3O2. Mole weight: 403.40. | |
| DHODH-IN-12 | DHODH-IN-12, a leflunomide derivative, is a weak inhibitor of dihydroorotate dehydrogenase (DHODH) with a pKa of 5.07. Synonyms: (2E)-2-cyano-2-(hydroxyimino)-N-(4-methylphenyl)ethanamide; Acetamide, 2-cyano-2-(hydroxyimino)-N-(4-methylphenyl)-, (2E)-. Grade: ≥95%. CAS No. 1263303-93-0. Molecular formula: C10H9N3O2. Mole weight: 203.20. | |
| DHODH-IN-13 | DHODH-IN-13, a hydroxyfurazan analogue of A771726, is an inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 4.3 μM for rat liver DHODH. It can be used for rheumatoid arthritis. Synonyms: 4-Oxo-N-[4-(trifluoromethyl)phenyl]-4,5-dihydro-1,2,5-oxadiazole-3-carboxamide; 1,2,5-Oxadiazole-3-carboxamide, 4,5-dihydro-4-oxo-N-[4-(trifluoromethyl)phenyl]-. Grade: ≥95%. CAS No. 1364791-86-5. Molecular formula: C10H6F3N3O3. Mole weight: 273.17. | |
| DHODH-IN-14 | DHODH-IN-14, a hydroxyfurazan analogue of A771726, is an inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 0.49 μM for rat liver DHODH. It can be used for rheumatoid arthritis. Synonyms: 4-Oxo-N-(2,3,5,6-tetrafluoro-4-biphenylyl)-4,5-dihydro-1,2,5-oxadiazole-3-carboxamide; 1,2,5-Oxadiazole-3-carboxamide, 4,5-dihydro-4-oxo-N-(2,3,5,6-tetrafluoro[1,1'-biphenyl]-4-yl)-. Grade: ≥95%. CAS No. 1364791-93-4. Molecular formula: C15H7F4N3O3. Mole weight: 353.23. | |
| DHODH-IN-15 | DHODH-IN-15, a hydroxyfurazan analogue of A771726, is an inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 11 μM for rat liver DHODH. It can be used for rheumatoid arthritis. Synonyms: N-(4-Biphenylyl)-4-oxo-4,5-dihydro-1,2,5-oxadiazole-3-carboxamide; 1,2,5-Oxadiazole-3-carboxamide, N-[1,1'-biphenyl]-4-yl-4,5-dihydro-4-oxo-. Grade: ≥95%. CAS No. 1364791-88-7. Molecular formula: C15H11N3O3. Mole weight: 281.27. | |
| DHODH-IN-16 | DHODH-IN-16 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 0.396 nM for human DHODH. Synonyms: 6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-7-fluoro-4-isopropyl-2-(o-tolyl)isoquinolin-1(2H)-one. Grade: ≥95%. CAS No. 2511248-11-4. Molecular formula: C24H25FN4O3. Mole weight: 436.48. | |
| DHODH-IN-3 | DHODH-IN-3 is a potent human dihydroorotate dehydrogenases (HsDHODH) inhibitor (IC50 = 261 nM), which has potential for the treatment of malaria. DHODH-IN-3 binds to the ubiquinone binding cavities in DHODH with a Kiapp of 32 nM. Synonyms: (2Z)-N-(3-Chloro-4-biphenylyl)-2-cyano-3-hydroxy-2-butenamide; 2-Butenamide, N-(3-chloro[1,1'-biphenyl]-4-yl)-2-cyano-3-hydroxy-, (2Z)-. Grade: ≥95%. CAS No. 1148126-04-8. Molecular formula: C17H13ClN2O2. Mole weight: 312.75. | |
| DHODH-IN-4 | DHODH-IN-4 is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor, with IC50 values of 4 μM and 0.18 μM for PfDHODH and HsDHODH, respectively. Synonyms: (2z)-2-cyano-N-(2',3-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide. CAS No. 1148125-93-2. Molecular formula: C17H12Cl2N2O2. Mole weight: 347.20. | |
| DHODH-IN-8 | DHODH-IN-8 is an inhibitor of human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) with IC50 of 0.13 μM and 47.4 μM, and Kis of 0.016 μM and 5.6 μM, respectively. Synonyms: (2z)-N-(2'-chlorobiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide. CAS No. 1148126-03-7. Molecular formula: C17H13ClN2O2. Mole weight: 312.75. | |
| DHODH-IN-9 | DHODH-IN-9, an azine-bearing analogue, is a human dihydroorotate dehydrogenase inhibitor with antiviral effect (pMIC50 = 7.4). Synonyms: 5-Cyclopropyl-2-[4-(2-fluorobenzyl)-3-isopropoxy-5-methyl-1H-pyrazol-1-yl]pyrimidine; hDHODH-IN-7; Pyrimidine, 5-cyclopropyl-2-[4-[(2-fluorophenyl)methyl]-5-methyl-3-(1-methylethoxy)-1H-pyrazol-1-yl]-. Grade: ≥95%. CAS No. 1644156-41-1. Molecular formula: C21H23FN4O. Mole weight: 366.43. | |
| D-Homo-16-alpha-hydroxyprednisolone | D-Homo-16-alpha-hydroxyprednisolone is a derivative of Prednisolone, which is a glucocorticoid and an anti-inflammatory drug used to treat central nervous system disorders. Synonyms: (2R,3R,4aS,4bS,10aR,10bS,11S,12aS)-2,3,11-Trihydroxy-2-(hydroxymethyl)-10a,12a-dimethyl-3,4,4a,5,6,10a,10b,11,12,12a-decahydro-1,8(2H,4bH)-chrysenedione; 1,8(2H,4bH)-Chrysenedione, 3,4,4a,5,6,10a,10b,11,12,12a-decahydro-2,3,11-trihydroxy-2-(hydroxymethyl)-10a,12a-dimethyl-, (2R,3R,4aS,4bS,10aR,10bS,11S,12aS)-. Molecular formula: C21H28O6. Mole weight: 376.44. | |
| D-Homo A Derivative of Dexamethasone | D-Homo A Derivative of Dexamethasone is an impurity of Desoxymetasone which is an anti-inflammatory agent. Molecular formula: C22H28FNa2O8P. Mole weight: 516.40. | |
| D-Homo A Derivative of Prednisolone | A derivative of Prednisolone. Prednisolone is a glucocorticoid and an anti-inflammatory drug used to treat central nervous system disorders. Grade: > 95%. Molecular formula: C21H29O8P. Mole weight: 440.43. | |
| D-Homo B Derivative of Betamethasone Sodium Phosphate | D-Homo B Derivative of Betamethasone Sodium Phosphate is a highly efficacious corticosteroid, finding extensive application in the biomedical field for the research of diverse inflammatory cutaneous ailments, such as psoriasand eczema. Emerging as a derivative of Betamethasone Sodium Phosphate, this particular product showcases noteworthy anti-inflammatory attributes, significantly treating the cardinal symptoms encompassing erythema, pruritus and edema characterizing these dermal pathologies. Synonyms: Betamethasone Sodium Phosphate Impurity D; RRT 0.81 bsp degradant. CAS No. 1201919-18-7. Molecular formula: C22H28FNa2O8P. Mole weight: 516.40. | |
| D-Homo B Derivative of Dexamethasone | D-Homo B Derivative of Dexamethasone is an impurity of Desoxymetasone which is an anti-inflammatory agent. Molecular formula: C22H30FO8P. Mole weight: 472.44. | |
| D-Homo B Derivative of Prednisolone | A derivative of Prednisolone. Prednisolone is a glucocorticoid and an anti-inflammatory drug used to treat central nervous system disorders. Grade: > 95%. Molecular formula: C21H29O8P. Mole weight: 440.43. | |
| D-Homocysteine Lactone | D-Homocysteine Lactone is an indispensable biomedical intermediate. Its ubiquitous utilization in the concoction of pharmaceutical drugs geared towards studying cardiovascular ailments, namely atherosclerosand thrombosis. Synonyms: (3R)-3-Aminooxolan-2-one. Grade: > 95%. CAS No. 51744-82-2. Molecular formula: C4H7NO2. Mole weight: 101.1. | |
| D-Homocysteine Thiolactone Hydrochloride | D-Homocysteine Thiolactone Hydrochloride is an indispensable and potent chemical entity widely used in synthesis of pioneering therapeutic agents designed to a panoply of medical conditions including cardiovascular afflictions, neurodegenerative maladies and malignant neoplasms. Synonyms: D-2-Amino-4-mercaptobutyric acid 1,4-thiolactone hydrochloride. Grade: > 95%. CAS No. 1120-77-0. Molecular formula: C4H8ClNOS. Mole weight: 153.63. | |
| DHPS-IN-1 | DHPS-IN-1 has the best DHPS inhibitory potency (IC50 = 0.014 μM). It shows excellent inhibitory effect on melanoma cells. CAS No. 2643300-54-1. Molecular formula: C17H13BrClN3O2. Mole weight: 406.66. | |
| DHQZ 36 | DHQZ 36 is a potent inhibitor of retrograde trafficking. It can protect cells from infections by human polyoma- and papillomaviruses. Synonyms: 2-(5-Ethylthiophen-2-yl)-6-fluoro-3-(4-fluorobenzyl)-2,3-dihydroquinazolin-4(1H)-one. Grade: 98%. CAS No. 1542098-94-1. Molecular formula: C21H18F2N2OS. Mole weight: 384.44. | |
| D-I03 | D-I03 is a potent and selective inhibitor of RAD52 with Kd of 25.8 μM, which specifically inhibits RAD52-dependent single-strand annealing (SSA) and D-loop formation. CAS No. 688342-78-1. Molecular formula: C23H36N6S. Mole weight: 428.64. | |
| Di(2-Amino-4-thiazolyl)acetyl Mirabegron | An impurity of Mirabegron. Mirabegron is a selective β3-adrenergic receptor agonist used primarily to treat symptoms of overactive bladder (OAB), including urinary urgency, frequency, and urge incontinence. Synonyms: Mirabegron Impurity 3; 2-Amino-N-[2-[4-[[2-[2-[[2-(2-amino-4-thiazolyl)acetyl]amino]-4-thiazolyl]acetyl]amino]phenyl]ethyl]-N-[(2R)-2-hydroxy-2-phenylethyl]-4-thiazoleacetamide; (R)-2-(2-Aminothiazol-4-yl)-N-(4-(2-(2-(2-(2-aminothiazol-4-yl)acetamido)thiazol-4-yl)acetamido)phenethyl)-N-(2-hydroxy-2-phenylethyl)acetamide. Grade: ≥95%. CAS No. 2762802-66-2. Molecular formula: C31H32N8O4S3. Mole weight: 676.83. | |
| DI-87 | DI-87 is an orally active and selective deoxycytidine kinase (dCK) inhibitor (EC50 = 10.2 nM) with antitumor activity. It is used in combination therapy against tumors expressing dCK. Synonyms: 4,6-Pyrimidinediamine, 2-[[(1R)-1-[2-[4-methoxy-3-[2-(4-morpholinyl)ethoxy]phenyl]-5-methyl-4-thiazolyl]ethyl]thio]-; (R)-2-((1-(2-(4-methoxy-3-(2-morpholinoethoxy)phenyl)-5-methylthiazol-4-yl)ethyl)thio)pyrimidine-4,6-diamine; NSC-798843; 2-{[(1R)-1-(2-{4-Methoxy-3-[2-(4-morpholinyl)ethoxy]phenyl}-5-methyl-1,3-thiazol-4-yl)ethyl]sulfanyl}-4,6-pyrimidinediamine. Grade: ≥95%. CAS No. 2107280-55-5. Molecular formula: C23H30N6O3S2. Mole weight: 502.65. | |
| diABZI-C2-NH2 | diABZI-C2-NH2 is an active analogue containing a primary amine functionality, which is a STING agonist. Synonyms: diABZI-C2-NH2; 2137975-93-8; SCHEMBL19449052; AKOS040757334; MS-31236; HY-137320; CS-0137673. Grade: 98%. CAS No. 2137975-93-8. Molecular formula: C36H43N13O4. Mole weight: 721.81. | |
| DiABZI STING agonist-1 | diABZI STING agonist-1 is a selective agonist of stimulator of interferon genes (STING) receptor, with EC50s of 130, 186 nM for human and mouse, respectively. Synonyms: 1H-Benzimidazole-5-carboxamide, 1-[(2E)-4-[5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-methoxy-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-[3-(4-morpholinyl)propoxy]-; (E)-1-(4-(5-carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzo[d]imidazole-5-carboxamide; STING agonist compound 3; 1-[(2E)-4-[5-(Aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-methoxy-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-[3-(4-morpholinyl)propoxy]-1H-benzimidazole-5-carboxamide. Grade: >98%. CAS No. 2138299-33-7. Molecular formula: C42H51N13O7. Mole weight: 849.94. | |
| DiABZI STING agonist-1 Tautomerism | DiABZI STING agonist-1 Tautomerism is a potent and selective STING agonist, which can activate the secretion of IFNβ, IL-6, TNF and KC/GROα, and has anti-tumor effects. Synonyms: 1H-Benzimidazole-5-carboxamide, 1-[(2E)-4-[(2E)-5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]imino]-2,3-dihydro-7-methoxy-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]imino]-2,3-dihydro-7-[3-(4-morpholinyl)propoxy]-, (2E)-; (2E)-1-[(2E)-4-[(2E)-5-(Aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]imino]-2,3-dihydro-7-methoxy-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]imino]-2,3-dihydro-7-[3-(4-morpholinyl)propoxy]-1H-benzimidazole-5-carboxamide; DiABZI. Grade: ≥98% by HPLC. CAS No. 2138498-18-5. Molecular formula: C42H51N13O7. Mole weight: 849.94. | |
| diABZI STING agonist 1 trihydrochloride | diABZI STING agonist-1-trihydrochloride is an agonist of stimulator of interferon genes (STING) for treating cancer. Synonyms: 1H-Benzimidazole-5-carboxamide, 1-[(2E)-4-[5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-methoxy-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-[3-(4-morpholinyl)propoxy]-, hydrochloride (1:3); (E)-1-(4-(5-Carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzimidazole-5-carboxamide tris(hydrochloride); DiABZI. Grade: ≥98%. CAS No. 2138299-34-8. Molecular formula: C42H54Cl3N13O7. Mole weight: 959.32. | |
| Diacerein | Diacerin is an inhibitor of pro-inflammatory cytokine Interleukin-1B (IL-1B) production, prescribed for osteoarthritis and chronic inflammatory arthritis. Uses: Treatment of osteoarthritis. Synonyms: Artrodar; Fisiodar; SF-277; Verboril; 4,5-Bis(acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic Acid. Grade: 98%. CAS No. 13739-02-1. Molecular formula: C19H12O8. Mole weight: 368.29. | |
| Diacetazotol | Diacetazotol, also referred to Pellidol, inhibits dioxin-induced ethoxyresorufin-O-deethylase (EROD) activity (IC50 = 75±4 nM) and has been used in ointment or dusting powder to stimulate wound epitheliazation. Synonyms: N-acetyl-N-[2-methyl-4-[(2-methylphenyl)diazenyl]phenyl]acetamide; 4-diacetylaminoazotoluene; Dermagan; diacetazotol; pellidol. CAS No. 83-63-6. Molecular formula: C18H19N3O2. Mole weight: 309.36. | |
| Diacetyldigoxigenin | Diacetyldigoxigenin is an intermediate used in the synthesis of Digoxigenin NHS-ester, which is a digoxin cross-linking reagent. Synonyms: Digoxigenin 3,12-diacetate; Card-20(22)-enolide, 3,12-bis(acetyloxy)-14-hydroxy-, (3β,5β,12β)-; (3β,5β,12β)-3,12-Diacetoxy-14-hydroxycard-20(22)-enolide; 3,12-Diacetyldigoxigenin; 3-β,12-β,14-Trihydroxy-5-β-card-20(22)-enolide 3,12-diacetate; 3β,12β-diacetoxy-14-hydroxy-5β,14β-card-20(22)-enolide; Digoxigenin diacetate. CAS No. 6078-59-7. Molecular formula: C27H38O7. Mole weight: 474.59. | |
| Diacetyl guanine | An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Synonyms: N2,9-Diacetylguanine; N,9-Diacetylguanine; N(2),9-Diacetylguanine; 2,9-Diacetylguanine. CAS No. 3056-33-5. Molecular formula: C9H9N5O3. Mole weight: 235.20. | |
| Di-a-D-galactosyl-mannopentaose | Di-a-D-galactosyl-mannopentaose is an eminent biomedical compound with remarkable ability to meticulously target and intricately modulate distinct receptors, thereby orchestrating an astute regulation of immune responses. Mole weight: 1153.00. | |
| Dialdehyde starch | Dialdehyde starch is a biocompatible polymer used in biomedical field for drug delivery systems. With excellent stability and biodegradability, it enables controlled drug release, especially for anticancer compounds like doxorubicin and paclitaxel. Synonyms: Starch, 2,3-dialdehydo; Sumstar; Dialdehydostarch; 2,3-Dialdehyde starch; 2,3-Dialdehydostarch; Caldas 10; DAS 100; Formamyl; Periodate starch; Polyaldehyde starch; Starch dialdehyde; Starch-2,3-dialdehyde; Sumstar 150; Sumstar 190. CAS No. 9047-50-1. | |
| Dialdehyde starch-methylenedianiline polymer | Dialdehyde starch-methylenedianiline polymer. Synonyms: Starch, 2,3-dialdehydo, polymer with 4,4'-methylenebis[benzenamine]; Benzenamine, 4,4'-methylenebis-, polymer with 2,3-dialdehydostarch; Starch Dialdehyde. Grade: >98%. CAS No. 9085-99-8. | |
| Dialuric Acid | Dialuric acid is a metabolite of Alloxan. Synonyms: 5-Hydroxy-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Hydroxybarbituric Acid; Dialuric Acid; 2,4,5,6-Pyrimidinetetrol; 5,6-Dihydroxyuracil; 5-Hydroxybarbituric Acid. Grade: ≥95%. CAS No. 444-15-5. Molecular formula: C4H4N2O4. Mole weight: 144.09. | |
| Diaminopyrazine-C-nucleoside CEP | Acknowledged as an indispensable entity within the biomedical industry, diaminopyrazine-C-nucleoside CEP stands tall as a profound compound. Its offering extends far beyond its mere presence, encompassing an unparalleled influence in the realm of novel pharmaceutical interventions. A vast array of afflictions, including the notorious cancers and viral infections, succumb to its far-reaching medicinal dominion. Molecular formula: C57H82ClN8O6P. Mole weight: 1041.74. | |
| Diamino triptycene | Diamino triptycene: Diamino triptycene is a compound that exhibits potential applications in studying cancer, particularly leukemia. With its unique chemical structure and properties, Diamino triptycene demonstrates promising antineoplastic activity. Synonyms: Triptycene diamine; 9,10-dihydro-9,10-[1,2]benzenoanthracene-1,2-diamine. Molecular formula: C20H16N2. Mole weight: 284.36. | |
| Dianhydrodaunomycinone | Dianhydrodaunomycinone is an impurity of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: Daunorubicin Impurity 4; 8-Acetyl-6,11-dihydroxy-1-methoxy-5,12-naphthacenedione; Bisanhydrodaunomycinone; 5,12-Naphthacenedione, 8-acetyl-6,11-dihydroxy-1-methoxy-; 5,12-Dihydro-6,11-dihydroxy-1-methoxy-8-acetyl-naphthacene-5,12-dione. Grade: ≥95%. CAS No. 32434-04-1. Molecular formula: C21H14O6. Mole weight: 362.34. | |
| Dianhydro Idarubicinaglycone | Dianhydro Idarubicinaglycone is a key intermediate for the improved synthesis of 4-demethoxydaunomycinone and daunomycinone, which are metabolites of Daunorubicin. Daunorubicin is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: 8-Acetyl-6,11-dihydroxy-5,12-tetracenedione; Bisanhydrous Idarubicin Aglycone; Idarubicin Impurity 1; 5,12-Naphthacenedione, 8-acetyl-6,11-dihydroxy-. Grade: ≥95%. CAS No. 84499-12-7. Molecular formula: C20H12O5. Mole weight: 332.31. | |
| Dianhydrovalrubicin | Dianhydrovalrubicin is an impurity of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: 2-(5,12-Dihydroxy-7-methoxy-6,11-dioxo-6,11-dihydrotetracen-2-yl)-2-oxoethyl Pentanoate; 2-(5,12-Dihydroxy-7-methoxy-6,11-dioxo-6,11-dihydro-2-tetracenyl)-2-oxoethyl valerate; Pentanoic acid, 2-(6,11-dihydro-5,12-dihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl)-2-oxoethyl ester. Grade: ≥95%. Molecular formula: C26H22O8. Mole weight: 462.45. | |
| Dianicline | Dianicline is subtype-selective, binding primarily to the α4β2 subtype as a selective α4β2 nAChR partial agonist (IC50 = 105 nM). Uses: Α4β2 nachr partial agonist. Synonyms: SSR-591,813; SSR 591,813; (5aS,8S,10aR)-5a,6,9,10-Tetrahydro-7H,11H-8,10a-methanopyrido[2',3':5,6]pyrano[2,3-d]azepine. Grade: ≥98%. CAS No. 292634-27-6. Molecular formula: C13H16N2O. Mole weight: 216.28. | |
| Diapamide | Diapamide is a new diuretic and antihypertensive agent. Uses: A new diuretic and antihypertensive agent. Synonyms: CN-36,337; CN-36337; CN 36337; CN36337; D 1593; D-1593; D1593; Diapamide; NSC 178204; Thiamizide; Tiamizid; Tiamizida. CI-456; CI456; CI 456; 4-chloro-N-methyl-3-(methylsulfamoyl)benzamide. Grade: ≥98%. CAS No. 3688-85-5. Molecular formula: C9H11ClN2O3S. Mole weight: 262.716. | |
| Diapocynin | Diapocynin is the dimeric form of the NADPH oxidase inhibitor apocynin that has anti-inflammatory and antioxidant activities. Diapocynin inhibits NADPH oxidase complex assembly and activation, gp91phox mRNA expression, and production of the pro-inflammatory cytokines. Diapocynin also reverses motor coordination deficits in the LRRK2R1441G mouse model of early Parkinson's disease. Synonyms: Dehydrodiacetovanillone; CHEMBL38775. Grade: ≥98%. CAS No. 29799-22-2. Molecular formula: C18H18O6. Mole weight: 330.3. | |
| Diaquo[(1R,2R)-1,2-cyclohexanediamine]platinum Dimer Dinitrate | A metabolite of Oxaliplatin, which is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Synonyms: Platinum(2+), bis(1,2-cyclohexanediamine-N,N')di-μ-hydroxydi-, stereoisomer, dinitrate; 1,2-Cyclohexanediamine, platinum complex, trans-; Oxaliplatin Impurity 2; (SP-4-2)-Di-oxobis[(1R,2R)-1,2-cyclohexanediamine-κN,κN']diplatinum(2+) Dinitrate; (SP-4-2)-Di-oxobis[(1R-trans)-1,2-cyclohexanediamine-N,N']diplatinum(2+) Dinitrate. Grade: ≥95%. CAS No. 82398-34-3. Molecular formula: C12H30N4O2Pt2.2NO3. Mole weight: 776.56. | |
| Di-Arg-Alarelin | Di-Arg-Alarelin is a modified form of Alarelin. Alarelin is a synthetic analog of Gonadotropin-releasing hormone (GnRH) used primarily for its effects on the reproductive system. It acts as a GnRH agonist, initially stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. Alarelin is used in the treatment of conditions such as endometriosis, uterine fibroids, and prostate cancer, as well as in assisted reproductive technologies. Synonyms: Glp-His-Trp-Ser-Tyr-DAla-Leu-Arg-Arg-Pro-NHEt; H-Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Arg-Pro-NHEt; Glp-HWSY-DAla-LRRP-NHEt; L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-arginyl-L-proline ethylamide; 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-arginyl-N-ethyl-L-Prolinamide; (+Arg8)-Alarelin; Glp-HWSYaLRRP-NHEt. Grade: ≥95%. Molecular formula: C62H90N20O13. Mole weight: 1323.53. | |
| Diarylpropionitrile | Diarylpropionitrile, also called as DPN, is a selective agonist of estrogen receptor β (ERβ) with a 70-fold higher relative binding affinity for ERβ(18%) versus ER (0.25%). ERβ: EC50=0.85 nM; ERα: EC50=66 nM. Synonyms: 2,3-BIS(4-HYDROXYPHENYL)-PROPIONITRILE; DPN; 2,3-bis(p-hydroxyphenyl)propionitrile; propionitrile,2,3-bis(p-hydroxyphenyl); 2,3-Bis(4-hydroxyphenyl)propanenitrile; 2,3-Bis(4-hydroxyphenyl)propiononitrile; Diarylpropionitrile. Grade: >99 %. CAS No. 1428-67-7. Molecular formula: C15H13NO2. Mole weight: 239.27. | |
| Di-Asn-Desmopressin | An impurity of Desmopressin. Desmopressin is a synthetic analogue of the hormone vasopressin, used to treat conditions such as central diabetes insipidus, nocturnal enuresis (bedwetting), and certain bleeding disorders like hemophilia A and von Willebrand disease. Synonyms: Mpr-Tyr-Phe-Gln-Asn-Asn-Cys-Pro-DArg-Gly-NH2(Mpr1&Cys7 bridge); Mpr-YFQNNCP-DArg-G-NH2(Mpr1&Cys7 bridge); deamino-Cys-Tyr-Phe-Gln-Asn-Asn-Cys-Pro-D-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys7); Deamino-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-asparagyl-L-cysteinyl-L-prolyl-D-arginyl-glycinamide (1->7)-disulfide; [Di-Asn5]-Desmopressin; (+Asn5)-Desmopressin. Grade: ≥95%. Molecular formula: C50H70N16O14S2. Mole weight: 1183.33. | |
| Diatrizoate sodium | Diatrizoate has been shown to cause partial redistribution of tight-junction-associated membrane proteins into a cytoplasmic compartment in cultured monolayer MDCK cells. Sodium diatrizoate induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium. Synonyms: Sodium diatrizoate; Triombrine; Hypaque sodium; Diatrizoic acid sodium salt; 3,5-Diacetamido-2,4,6-triiodobenzoic acid sodium salt. Grade: ≥98%. CAS No. 737-31-5. Molecular formula: C11H8I3N2NaO4. Mole weight: 635.89. | |
| Diazepinomicin | Diazepinomicin, also known as TLN-4601, is a small-molecule inhibitor of the RAS/RAF/MAPK signaling pathway with potential antineoplastic activity. Diazepinomicin binds to and inhibits Ras kinase, thereby preventing the phosphorylation and activation of proteins downstream of the Ras signal transduction pathway, including serine/threonine kinase RAF (BRAF) and extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK-2). This agent also selectively binds to the peripheral benzodiazepine receptor (PBR), a receptor highly expressed in certain tumor cell types cells, inducing cell cycle arrest and apoptosis in PBR-expressing cells. Diazepinomicin can cross the blood-brain barrier (BBB). Synonyms: TLN-4601; TLN 4601; TLN4601; ECO 4601; ECO4601; BU 4664L; ECO 04601; BU4664L; BU-4664L; 4,6,8-trihydroxy-10-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)-5H-dibenzo[b,e][1,4]diazepin-11(10H)-one. CAS No. 733035-26-2. Molecular formula: C28H34N2O4. Mole weight: 462.59. | |
| Diaziquone | A 1,4-benzoquinone that is substituted at positions 2 and 5 by aziridin-1-yl groups and at positions 3 and 6 by (ethoxycarbonyl)amino groups. It cross-links DNA during the cell cycle thus resulting in cell cycle arrest and apoptosis. Synonyms: CI-904; CI 904; CI904; Aziridinylbenzoquinone; Diaziquonum; NSC 182986; 2,5-Diaziridinyl-3,6-bis(carboethoxyamino)-1,4-benzoquinone. Grade: >98%. CAS No. 57998-68-2. Molecular formula: C16H20N4O6. Mole weight: 364.36. | |
| Diazoline | Diazoline is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis. Synonyms: Mebhydrolin napadisylate; Omeril; Diazolin; Incidal; mebhydroline 1,5-naphthalenedisulfonate. Grade: 98% (HPLC). CAS No. 6153-33-9. Molecular formula: C48H48N4O6S2. Mole weight: 841.04. | |
| Diazoxide | Diazoxide is a potassium channel activator that causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. The cellular release of potassium switches off voltage-gated calcium ion channels which inhibits the generation of an action potential. Uses: Antihypertensive agents. Synonyms: 7-Chloro-3-methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide. Grade: 98% (TLC). CAS No. 364-98-7. Molecular formula: C8H7ClN2O2S. Mole weight: 230.7. | |
| DIBA | DIBA, a benzamide derivative, has been found to be an ER zinc finger inhibitor that could be significant in studies of breast cancers. Synonyms: DIBA; PD-22551; PD022551; DIBA (Antineoplastic); DIBA-1; NSC 654077; PD 22551; N-(4-sulfamoylphenyl)-2-[[2-[(4-sulfamoylphenyl)carbamoyl]phenyl]disulfanyl]benzamide. Grade: 98%. CAS No. 171744-39-1. Molecular formula: C26H22N4O6S4. Mole weight: 614.74. | |
| Dibaclofen Urea Dicyclohexylammonium Salt | Dibaclofen Urea Dicyclohexylammonium Salt is an impurity of Baclofen, which is a specific GABA-B receptor agonist and muscle relaxant (skeletal). It is primarily used to treat spasticity. Grade: 95%. Molecular formula: C45H68Cl2N4O5. Mole weight: 815.95. | |
| Di-baclofen Urea Dimethyl Ester | Di-baclofen Urea Dimethyl Ester is the impurity of Baclofen, which is a specific GABA-B receptor agonist and muscle relaxant (skeletal). It is primarily used to treat spasticity. Molecular formula: C23H26Cl2N2O5. Mole weight: 481.37. | |
| Dibanzyloxy Fosfocreatinine | Dibanzyloxy Fosfocreatinine is an immensely powerful compound, used in studying a multitude of malignancies and neurodegenerative ailments. Synonyms: Dibanzyloxy Phosphatecreatinine; Creatininephosphoric acid dibenzyl ester; Dibenzyl (1-methyl-4-oxoimidazolidin-2-ylidene)phosphoramidate; N-(1-Methyl-4-oxoimidazolidin-2-ylidene)amidophosphoric acid bis(phenylmethyl) ester. Grade: > 95%. CAS No. 19208-69-6. Molecular formula: C18H20N3O4P. Mole weight: 373.35. | |
| Di-b-D-xylopyranosylamine | Di-b-D-xylopyranosylamine is a groundbreaking compound showcasing remarkable potential in curbing the proliferation of malignant cancer cells and studying perplexing neurological disorders. Synonyms: N-β-D-Xylopyranosyl-β-D-xylopyranosylamine; Di-β-D-xylopyranosylamine; (2R,2'R,3R,3'R,4S,4'S,5R,5'R)-2,2'-Azanediylbis(tetrahydro-2H-pyran-3,4,5-triol). CAS No. 62983-70-4. Molecular formula: C10H19NO8. Mole weight: 281.26. | |
| Dibenzothiophene | Dibenzothiophene (DBT) is a model compound for organic sulfur in fossil fuels. Synonyms: Dibenzothiophene; NSC 2843; NSC-2843; NSC2843. Grade: >98%. CAS No. 132-65-0. Molecular formula: C12H8S. Mole weight: 184.26. | |
| Dibenzoylmethan-d12 | One of the isotopic labelled form of Dibenzoylmethan, which is a kind of aromatic compound ahd has been found to restrain tumorigenesis in mice. Synonyms: 1,3-Diphenyl-1,3-propanedione; 2-Benzoylacetophenone-d12; Phenyl Phenacyl Ketone-d12. Molecular formula: C15O2D12. Mole weight: 236.33. | |
| Dibenzoyl thiamine | Dibenzoyl Thiamine, a lipophilic derivative of vitamin B, is a type of food additive that can be rapidly absorbed into the body and converted to thiamine. Synonyms: Bentiamine; O,S-Dibenzoylthiamine; Bentiamine; Dibenzoylthiamine; O,S-Dibenzoylthiamine. Grade: >98.0%(T). CAS No. 299-88-7. Molecular formula: C26H26N4O4S. Mole weight: 490.57. | |
| Dibenzyl Dipyridamole Tartaric Acid Ester | Dibenzyl Dipyridamole Tartaric Acid Ester is an intermediate in synthesizing Dipyridamole Tartaric Acid Ester Ammonium Salt, a Dipyridamole derivative. Synonyms: (2S,3S)-2,3-Bis(benzyloxy)-4-(2-((6-(bis(2-hydroxyethyl)amino)-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-2-yl)(2-hydroxyethyl)amino)ethoxy)-4-oxobutanoic Acid. Molecular formula: C42H56N8O9. Mole weight: 816.94. | |
| Dibenzyl Phosphate | Phosphoric Acid Dibenzyl Ester has the eye irritant property. Synonyms: bis(phenylmethyl) hydrogen phosphate; dibenzyl hydrogen phosphate. Grade: > 95 %. CAS No. 1623-08-1. Molecular formula: C14H15O4P. Mole weight: 278.24. | |
| Dibromo-Acetaldehyde | Dibromoacetaldehyde is used in analytical studies for micro liquid-liquid extraction combined with large volume injection gas chromatography-mass spectrometry for determination of haloacetaldehydes in treated water. Synonyms: Dibromoacetaldehyde. Grade: > 95%. CAS No. 3039-13-2. Molecular formula: C2H2Br2O. Mole weight: 201.85. | |
| Dibromo Cotinine Hydrobromide Perbromide | Dibromo Cotinine Hydrobromide Perbromide is a derivative of Cotinine, which is currently being used to treat depression, PTSD, schizophrenia, Alzheimer's disease and Parkinson's disease. Synonyms: 3,5-Dibromo-1-methyl-5-(3-pyridinyl)-2-pyrrolidinone mono(hydrogen tribromide). Molecular formula: C10H11Br5N2O. Mole weight: 574.73. | |
| Dibromodulcitol | Dibromodulcitol is a compound harnessing its potential in studyting multifarious cancers including breast, lung and ovarian cancer. Uses: Antineoplastic agents, alkylating. Synonyms: 1,6-Dibromo-1,6-dideoxy-D-galactitol. CAS No. 10318-26-0. Molecular formula: C6H12Br2O4. Mole weight: 307.97. | |
| Dibucaine | Dibucaine is an amide local anesthetic. Among the most potent and toxic of the long-acting local anesthetics, current use of cinchocaine is generally restricted to spinal and topical anesthesia. Uses: Dibucaine is an anesthetic of the amide type. it is mainly used for surface anesthesia and now restricted to use in spinal and topical anesthesia. Synonyms: 2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide. Grade: > 95%. CAS No. 85-79-0. Molecular formula: C20H29N3O2. Mole weight: 343.47. | |
| Dibucaine Impurity D | Dibucaine Impurity. Synonyms: 2-butoxyquinoline-4-carboxylic Acid; 10222-61-4; 4-Quinolinecarboxylic acid, 2-butoxy-; Dibucaine Impurity D; 2-(n-butyloxy)-4-quinolinecarboxylic acid; WW4AV6ZX47; Cinchoninic acid, 2-butoxy-; 2-Butoxy-4-quinolinecarboxylic acid; butyloxycinchoninic acid; UNII-WW4AV6ZX47; SCHEMBL6250517; ZISCTCXYESUBGA-UHFFFAOYSA-N; 2-Butoxyquinoline-4-carboxylicAcid; BCP24400; MFCD11527607; 2-n-Butoxy-4-quinolinecarboxylic acid; AKOS009411458; DS-9690; SB72026; Cinchocaine hydrochloride impurity D [EP]; CS-0186594; I11553; CINCHOCAINE HYDROCHLORIDE IMPURITY D [EP IMPURITY]. Grade: > 95%. CAS No. 10222-61-4. Molecular formula: C14H15NO3. Mole weight: 245.28. | |
| Dibutyryladenosine cyclic 3',5'-monophosphate | Bucladesine is a 3',5'-cyclic purine nucleotide that is the 2'-butanoate ester and 6-N-butanoyl derivative of 3',5'-cyclic AMP. It has a role as an agonist, a vasodilator agent and a cardiotonic drug. It is a butyrate ester, a 3',5'-cyclic purine nucleotide and a member of butanamides. It derives from a 3',5'-cyclic AMP. Synonyms: Butyramide, N-(9-β-D-ribofuranosyl-9H-purin-6-yl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butyrate; 3',5'-Cyclic AMP dibutyrate; Actosin; Bucladesine; Cyclic AMP dibutyrate; Cyclic AMP N6,2'-O-dibutyrate; Cyclic dibutyryl-AMP; dbcAMP; Dibutyryl 3',5'-cyclic adenosine monophosphate; Dibutyryl 3',5'-cyclic AMP; Dibutyryl cAMP; Dibutyryladenosine 3',5'-cyclic phosphate; Dibutyryladenosine cyclic monophosphate; N6,2'-O-Dibutyryl cAMP; N6,2'-O-Dibutyryl cyclic 3',5'-adenosine monophosphate; N6,2'-O-Dibutyryl cyclic 3',5'-AMP; N6,O2'-Dibutyryl cyclic AMP; N6,O2'-Dibutyryl-3',5'-cyclic AMP; N6,O2'-Dibutyryl-cAMP; N6,O2'-Dibutyryladenosine 3',5'-monophosphate; N6-2'-O-Dibutyryl-3',5'-AMP; NSC 143108. Grade: 99%. CAS No. 362-74-3. Molecular formula: C18H24N5O8P. Mole weight: 469.39. | |
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