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N-Desmethyl Rifampicin
A metabolite of Rifampicin. Rifampicin is an antibiotic used to treat several types of bacterial infections. This includes tuberculosis, leprosy, and Legionnaire's. Synonyms: 3-[(1-Piperazinylimino)methyl]-rifamycin; 3-Piperazinoiminomethyl Rifamycin SV; 4-N-Demethylrifampicin; AF/AP; Demethylrifampicin; N-Demethylrifampicin; N-Demethylrifampin; NSC 143416; Rifampicin AF/AP; Rifampin. Grades: > 95%. CAS No. 13292-45-0. Molecular formula: C42H56N4O12. Mole weight: 808.93.
N-Desmethyl Rivastigmine
A impurity of Rivastigmine.Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: N-Ethylcarbamic Acid 3-[(1S)-1-(Dimethylamino)ethyl]phenyl Ester. Grades: > 95%. CAS No. 1070660-34-2. Molecular formula: C13H20N2O2. Mole weight: 236.32.
N-Desmethyl rosiglitazone
An impurity of Rosiglitazone.Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. Synonyms: 5-[[4-[2-(2-Pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione; SB 237216. Grades: > 95%. CAS No. 257892-31-2. Molecular formula: C17H17N3O3S. Mole weight: 343.41.
N-Desmethyl Rosuvastatin Disodium Salt
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Grades: > 95%. Molecular formula: C21H24FN3O6S. 2 Na. Mole weight: 511.49.
N-Desmethyl Rosuvastatin Ethyl Ester
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Grades: > 95%. Molecular formula: C23H30FN3O6S. Mole weight: 495.57.
N-Desmethyl Rosuvastatin Methyl Ester
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Grades: > 95%. Molecular formula: C22H27FN3O6S. Mole weight: 480.54.
N-Desmethyl Sildenafil
Cas No. 139755-82-1.
N-Desmethyl Tapentadol
One of the metabolite impurities of Tapentadol, which is a centrally acting analgesic agent. Synonyms: 3-[(1R,2R)-1-Ethyl-2-methyl-3-(methylamino)propyl]phenol. Grades: > 95%. Molecular formula: C13H21NO. HCl. Mole weight: 243.78.
N-Desmethyl Topotecan
One of the impurities of Topotecan, which is a topoisomerase I inhibitor and has been found to be an effective antineoplastic agent. Synonyms: (4S)-4-Ethyl-4,9-dihydroxy-10-[(methylamino)methyl]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione. CAS No. 190710-79-3. Molecular formula: C23H23N3O5. Mole weight: 407.43.
N-Desmethyl Toremifene
One of the impurities of Toremifene, which has been found to be effective as an antiestrogen as well as antineoplastic agent. Synonyms: 2-[4-[(1Z)-4-Chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-N-methylethanamine; (Z)-4-Chloro-1,2-diphenyl-1-[4-[2-(N-methylamino)ethoxy]phenyl]-1-butene. CAS No. 110503-61-2. Molecular formula: C25H26ClNO. Mole weight: 391.95.
N-Desmethyl Trimebutine-beta-D-Glucuronide
An impurity of Trimebutine. Trimebutine is an opioid receptor agonist used as antispasmodic. Molecular formula: C26H33NO11. Mole weight: 535.55.
N-Desmethyl Trimebutine HCl
N-Desmethyl Trimebutine HCl is the main metabolite of Trimebutine. Synonyms: N-Demethyl Trimebutine Hydrochloride; 3,4,5-Trimethoxybenzoic Acid 2-(Methylamino)-2-phenylbutyl Ester Hydrochloride; N-Monodesmethyltrimebutine Hydrochloride; JO 1069 Hydrochloride; Nortrimebutine Hydrochloride. CAS No. 294882-33-0. Molecular formula: C21H27NO5. HCl. Mole weight: 409.9.
N-Desmethyl Ulipristal
N-Desmethyl Ulipristal is a metabolite of Ulipristal. Ulipristal is a selective progesterone receptor modulator (SPRM) used for emergency contraception and uterine fibroid. Synonyms: (11β)-17-Hydroxy-11-[4-(methylamino)phenyl]-19-norpregna-4,9-diene-3,20-dione. CAS No. 159681-67-1. Molecular formula: C27H33NO3. Mole weight: 419.57.
N-Desmethyl Zolmitriptan
One of the impurities of Zolmitriptan, which is a 5HTID-receptor agonist and has been found to be effective in the treatment of migraine. Synonyms: (4S)-4-[[3-[2-(Methylamino)ethyl]-1H-indol-5-yl]methyl-2-oxazolidinone; 183C91; Zolmitriptan USP Related Compound A. CAS No. 139264-35-0. Molecular formula: C15H19N3O2. Mole weight: 273.34.
N-Desmethyl zopiclone Hydrochloride
One of the impurities of Zopiclone, which is a GABAA receptor agonist and could be used as a sedative as well as hypnotic agent. Synonyms: Piperazine-1-carboxylic Acid 6-(5-Chloro-pyridin-2-yl)-7-oxo-6,7-dihydro- 5H-pyrrolo[3,4-b]pyrazin-5yl Ester Hydrochloride. CAS No. 59878-63-6. Molecular formula: C16H16Cl2N6O3. Mole weight: 411.24.
N-Despropyl propafenone HCl
A metabolite of Propafenone.Propafenone is an anti-arrhythmic medication.It can be used for the treatment of illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias. Synonyms: 1-[2-(3-Amino-2-hydroxypropoxy)phenyl]-3-phenyl-1-propanone Hydrochloride. Grades: > 95%. CAS No. 1188263-52-6. Molecular formula: C18H21NO3.HCl. Mole weight: 335.83.
N-Didesethyl Quinagolide
A metabolite of Quinagolide. Quinagolide is a selective D2 receptor agonist. It can be used to reduce elevated levels of prolactin (hyperprolactinemia). Grades: > 95%. Molecular formula: C16H25N3O3S. Mole weight: 339.46.
N-didesmethyl Oxytetracycline
An impurity of Oxytetracycline which is a tetracycline analog used to reduce the development of drug-resistant bacteria. Grades: > 95%. Molecular formula: C19H18N2O10. Mole weight: 434.36.
N-Didesmethyl Trimebutine HCl
N-Didesmethyl Trimebutine HCl is a metabolite of Trimebutine. Trimebutine is an opioid receptor agonist used as antispasmodic. Synonyms: N,N-Didesmethyl Trimebutine Hydrochloride; 3,4,5-Trimethoxybenzoic Acid 2-Amino-2-phenylbutyl Ester Hydrochloride. CAS No. 84333-60-8. Molecular formula: C20H25NO5.HCl. Mole weight: 395.88.
N-Dimethyl Rivastigmine (Rivastigmine EP Impurity B)
A impurity of Rivastigmine.Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: Dimethylcarbamic Acid 3-[1-(Dimethylamino)ethyl]phenyl Ester; Dimethylcarbamic Acid m-[1-(Dimethylamino)ethyl]phenyl Ester; m-[1- (dimethylamino) ethyl]phenolDimethylcarbamate (ester); USP Rivastigmine Related Compound B. Grades: > 95%. CAS No. 25081-93-0. Molecular formula: C13H20N2O2. Mole weight: 236.32.
Nebivolol
Nebivolol, a highly selective β1-adrenergic receptor inhibitor, has vasodilatory effect so that could be effective against hypertension. It was just withdrawed a Phase II/III trial for Hypertension in patients with chronic obstructive pulmonary disease. Synonyms: 2H-1-Benzopyran-2-methanol, α,α'-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-, [2R*[R*[R*(S*)]]]-(±)-; rel-(αR,α'R,2R,2'S)-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]; (±)-[2R*(1S*5S*(S*))]-α,α'-[Iminobis(methylene)bis(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol); (±)-Nebivolol; Bystolic; dl-Nebivolol; Nobiten; R 065824; Vasoxen. Grades: ≥95%. CAS No. 118457-14-0. Molecular formula: C22H25F2NO4. Mole weight: 405.44.
Nebivolol HCl
Nebivolol selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM. Uses: Adrenergic beta-1 receptor agonists. Synonyms: Nebivolol HCl; Nebivolol Hydrochloride; Silostar; Bystolic, R-67145; R 67145; R67145. Grades: >98%. CAS No. 152520-56-4. Molecular formula: C22H25F2NO4.HCl. Mole weight: 441.9.
Nebivolol Impurity 1
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.19 nM. Synonyms: (R,R,S,S)-Nebivolol; (αR,α'S,2R,2'S)-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol; (R)-1-((R)-6-Fluorochroman-2-yl)-2-(((S)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethanol. Grades: > 95%. CAS No. 1360598-84-0. Molecular formula: C22H25F2NO4. HCl. Mole weight: 405.45.
Nebivolol Impurity 10 HCl (RS,SR)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.31 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αS,?α'S,?2R,?2'R)?-. Grades: > 95%. CAS No. 920275-23-6. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Impurity 11 (SR,SR)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.32 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αS,?α'R,?2S,?2'R)?-. Grades: > 95%. Molecular formula: C22H25F2NO4. Mole weight: 405.45.
Nebivolol Impurity 12 HCl (RR,RR)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.33 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'R,?2R,?2'R)?-. Grades: > 95%. CAS No. 920275-25-8. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Impurity 13 HCl (SS,SS)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.34 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αS,?α'S,?2S,?2'S)?-. Grades: > 95%. CAS No. 920275-27-0. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Impurity 14 (D-Nebivolol) (SR,RR) HCl
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.35 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'R,?2R,?2'S)?-. Grades: > 95%. CAS No. 213132-06-0. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Impurity 2 HCl (SR,RS)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.20 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'R,?2S,?2'S)?-. Grades: > 95%. CAS No. 920275-19-0. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Impurity 3
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.24 nM. Synonyms: 2H-1-Benzopyran-2-methanol, 6-fluoro-3,?4-dihydro-α-[[(phenylmethyl)?amino]?methyl]?-, (αR,?2R)?-. Grades: > 95%. CAS No. 1029684-20-5. Molecular formula: C17H18FNO2. Mole weight: 287.34.
Nebivolol Impurity 4
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.25 nM. Synonyms: 2H-1-Benzopyran-2-methanol, 6-fluoro-3,?4-dihydro-α-[[(phenylmethyl)?amino]?methyl]?-, (αS,?2S)?-. Grades: > 95%. CAS No. 129050-29-9. Molecular formula: C17H18FNO2. Mole weight: 287.34.
Nebivolol Impurity 5
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.26 nM. Synonyms: 2H-1-Benzopyran-2-methanol, 6-fluoro-3,?4-dihydro-α-[[(phenylmethyl)?amino]?methyl]?-. Grades: > 95%. CAS No. 99199-91-4. Molecular formula: C17H18FNO2. Mole weight: 287.34.
Nebivolol Impurity 6 (SS)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.27 nM. Synonyms: (S)-(benzylamino)((S)-chroman-2-yl)methanol. Grades: > 95%. Molecular formula: C12H16FNO2. Mole weight: 225.26.
Nebivolol Impurity 7 (RR)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.28 nM. Synonyms: (R)-(benzylamino)((R)-chroman-2-yl)methanol. Grades: > 95%. Molecular formula: C12H16FNO2. Mole weight: 225.27.
Nebivolol Impurity 8 (SR)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.29 nM. Synonyms: (S)-(benzylamino)((R)-chroman-2-yl)methanol. Grades: > 95%. Molecular formula: C12H16FNO2. Mole weight: 225.27.
Nebivolol Impurity 9 (RS)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.30 nM. Synonyms: (R)-(benzylamino)((S)-chroman-2-yl)methanol. Grades: > 95%. Molecular formula: C12H16FNO2. Mole weight: 225.27.
Nebivolol Impurity A
This active molecular is a β-adrenergic receptor antagonist. Levonebivolol is an enantiomer of Nebivolol which is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and left ventricular failure in Europe. It is highly cardioselective under certain circumstances. In Apr 2015, US FDA approved an ANDA for nebivolol submitted by Amerigen. In Jan 2016, Forest Laboratories and the University of Chicago withdrew a phase II/III trial for Hypertension in patients with chronic obstructive pulmonary disease in USA. Uses: Treatment of hypertension and left ventricular failure. Synonyms: R67145; R-67145; R 67145; Levonebivolol. (αS,α'S,2R,2'S)-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]; [2S-[2R*[R*[R*(S*)]]]]-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro- 2H-1-benzopyran-2-methanol; Levonebivolol; R 67145; l-Nebivolol. Grades: 98%. CAS No. 118457-16-2. Molecular formula: C22H25F2NO4. Mole weight: 405.44.
Nebivolol Impurity B (SR,SS)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.17 nM. Synonyms: [2S-[2R*[R*[S*(R*)]]]]-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol. Grades: > 95%. CAS No. 119365-25-2. Molecular formula: C22H25F2NO4. Mole weight: 405.45.
Nebivolol Impurity I HCl (RR,SR)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.21 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'S,?2R,?2'R)?-. Grades: > 95%. CAS No. 920275-20-3. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Impurity II HCl (SS,RS)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.22 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'S,?2S,?2'S)?-. Grades: > 95%. CAS No. 920299-27-0. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol O-Beta-D-Glucuronide
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.10 nM. Synonyms: Nebivolol O-β-D-Glucuronide; 6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-[2-[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-hydroxyethyl]amino]ethyl β-D-Glucopyranosiduronic Acid. Grades: > 95%. Molecular formula: C28H33F2NO10. Mole weight: 581.57.
Nebivolol Related Compound 1 HCl (Mixture of (RR,SR) and (SS,RS) Isomer)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.36 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'R,?2S,?2'R)?-; + 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αS,?α'S,?2R,?2'S)?-. Grades: > 95%. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Related Compound 2(Mixture of Diastereomers)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.37 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, (αR,?α'R,?2R,?2'S)?-; + 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, (αS,?α'S,?2R,?2'S)?-. Grades: > 95%. Molecular formula: C22H25F2NO4. Mole weight: 405.45.
Nebivolol Related Compound 3 HCl (Mixture of (RS,SR), (SR,SR) and (SR,RS) Isomers)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.38 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'S,?2S,?2'R)?-; + 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αS,?α'R,?2S,?2'R)?-; 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αS,?α'R,?2S,?2'R)?-. Grades: > 95%. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Related Compound 4 (Mixture of (R,R) and (S,S) Isomers)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.39 nM. Synonyms: (S)-(benzylamino)((S)-chroman-2-yl)methanol;& (R)-(benzylamino)((R)-chroman-2-yl)methanol. Grades: > 95%. Molecular formula: C12H16FNO2. Mole weight: 225.27.
Neosartoricin A
Neosartoricin is a prenylated tricyclic polyketide that inhibits the proliferation of anti-CD3 and anti-CD28-stimulated mouse spleen T cells (IC50 = 2.99 μM). Grades: >95% by HPLC. CAS No. 1421941-29-8. Molecular formula: C26H28O9. Mole weight: 484.49.
Neosartoricin B
Neosartoricin B is a polyketide originally isolated from A. nidulans heterologously expressing dermatophyte-derived polyketide synthase genes. Synonyms: NSC 34758. Grades: >95% by HPLC. CAS No. 1421708-43-1. Molecular formula: C24H26O8. Mole weight: 442.46.
N-Ethoxycarbonyl Ciprofloxacin
An impurity of Ciprofloxacin, which is a broad-spectrum antimicrobial carboxyfluoroquinoline, an fluoroquinolone antibiotic that is widely used as an antimicrobial and immunomodulatory agent. Synonyms: 7-[4-(Ethoxycarbonyl)-1-piperazinyl]-1-cyclopropyl-6-fluoro-3-carboxy-1,4-dihydro-4-oxoquinoline; 1-Cyclopropyl-7-[4-(ethoxycarbonyl)-1-piperazinyl]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid. Grades: > 95%. CAS No. 93594-29-7. Molecular formula: C20H22FN3O5. Mole weight: 403.41.
N-Ethyl Bimatoprost is one of Bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Synonyms: Bimatoprost Diethyl Amide; Bimatoprost Impurity 1. Molecular formula: C27H41NO4. Mole weight: 443.62.
N-Ethyl Tadalafil
One of the impurities of Tadalafil, which is an inhibitor of phosphodiesterase 5 and could be used in the treatmen of erectile dysfunction. Synonyms: Pyrazino[1',?2':1,?6]?pyrido[3,?4-b]?indole-1,?4-dione, 6-(1,?3-benzodioxol-5-yl)?-2-ethyl-2,?3,?6,?7,?12,?12a-hexahydro-, (6R,?12aR)?-. Grades: > 95%. CAS No. 1609405-34-6. Molecular formula: C23H21N3O4. Mole weight: 403.44.
N-Formyl Amlodipine
N-Formyl Amlodipine is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: N-Fmoc-trans-Hydroxy Proline; 4-(2-Chlorophenyl)-2-[[2-(formylamino)ethoxy]methyl]-1,4-dihydro-6-methyl-,3,5-pyridinedicarboxylic Acid 3-ethyl 5-methyl Ester. Grades: >95%. CAS No. 93848-81-8. Molecular formula: C21H25ClN2O6. Mole weight: 436.88.
N-Formyl Desloratadine (Desloratadine Impurity D)
Cas No. 117810-61-4.
N-Formyl Sitagliptin
N-Formyl Sitagliptin is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: N-(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)formamide; (R)-N-(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)formamide. Grades: >90%. Molecular formula: C17H15F6N5O2. Mole weight: 435.32.
N-Hydroxylated Vortioxetine Glucuronide
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C24H30N2O7S. Mole weight: 490.58.
N-Hydroxy Pentamidine Acetate (salt)
An impurity of Pentamidine which is an antiprotozoal agent used to treat Pneumocystis jiroveci pneumonia (PCP) African and trypanosomiasis, leishmaniasis, babesiosis. Synonyms: Pentamidine Amidoxime; N-Hydroxypentamidine; 130349-07-4; 4- [5- [4- [ (Z) -N'-hydroxycarbamimidoyl] phenoxy] pentoxy] benzenecarboximidamide; SCHEMBL8740422; UREYBSXWRHBDHQ-UHFFFAOYSA-N; J-005797. Grades: > 95%. CAS No. 130349-07-4. Molecular formula: C19H24N4O3.2/3.C2H4O2. Mole weight: 446.505.
N-Hydroxy Phentermine
N-Hydroxy Phentermine is a metabolite of Phentermine. Synonyms: N-Hydroxy-α,α-dimethylbenzeneethanamine; 2-Hydroxylamino-2-methyl-1-phenylpropane. Grades: > 95%. CAS No. 38473-30-2. Molecular formula: C10H15NO. Mole weight: 165.24.
N-Hydroxy Riluzole
A metabolite of Riluzole. Synonyms: N-Hydroxy-6-(trifluoromethoxy)-2-benzothiazolamine; 6-(Trifluoromethoxy)-2(3H)- benzothiazolone Oxime; 2-Hydroxyamino-6-(trifluoromethoxy)benzothiazole. Grades: > 95%. CAS No. 179070-90-7. Molecular formula: C8H5F3N2O2S. Mole weight: 250.2.
N-Hydroxy Riluzole-N-Glucuronide
A derivative of Riluzole and is used as a reagent in the synthesis of N-(benzo[d]thiazol-2-ylcarbamoyl)-2-methyl-4-oxoquinazoline-3(4H)-carbothioamide derivatives which exhibit anticonvulsant activity. Grades: > 95%. Molecular formula: C14H13F3N2O8S. Mole weight: 426.33.
N-Hydroxy Riluzole-O-Glucuronide Lithium Salt
An impurity of Riluzole. Grades: > 95%. Molecular formula: C14H12F3N2O8S. Li. Mole weight: 432.26.
N-Hydroxy Sulfamethoxazole
An impurity of Sulfamethoxazole. Sulfamethoxazole is an antibiotic and a structural analog of para-aminobenzoic acid (PABA). It compete with PABA to bind to dihydropteroate synthetase to inhibit the synthesis of dihydrofolic acid. Synonyms: 4-(Hydroxyamino)-N-(5-methyl-3-isoxazolyl)-benzenesulfonamide; Sulfamethoxazole N4-Hydroxylamine; Sulfamethoxazole Hydroxylamine; NSC 665547. Grades: > 95%. CAS No. 114438-33-4. Molecular formula: C10H11N3O4S. Mole weight: 269.28.
N-Hydroxy Thalidomide
A metabolite of Thalidomide which was prescribed as an anti-nausea agent to help pregnant women with morning sickness but withdrawn from the market when it was discovered to cause birth defects. Grades: > 95%. Molecular formula: C13H10N2O5. Mole weight: 274.24.
N-Hydroxy Varenicline
An impurity of Varenicline. Varenicline is a partial agonist of nicotinic receptor used for smoking cessation. It reduces both the desire for and the pleasure of cigarettes. Synonyms: Varenicline Impurity 4; 9,10-dihydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-8(7H)-ol. Molecular formula: C13H13N3O. Mole weight: 227.27.
Nifuratel Impurity A
An impurity of Nifuratel. Nifuratel, as a broad antibacterial spectrum agent, is used as an antibacterial, antifungal, and antiprotozoal. Synonyms: Nitrofurfural Diacetate;5-Nitro-2-furaldehyde Diacetate. Grades: > 95%. CAS No. 92-55-7. Molecular formula: C9H9NO7. Mole weight: 243.17.
Nifuratel Impurity B
An imppurity of Nifuratel is, as a broad antibacterial spectrum agent, which is used as an antibacterial, antifungal, and antiprotozoal. Synonyms: 5-Nitrofuraldazine; 5-nitro-2-furaldehyde (5-nitrofurfurylene)hydrazone. Grades: > 95%. CAS No. 736-53-8. Molecular formula: C10H6N4O6. Mole weight: 278.18.
Nimesulide
Nimesulide is a selective COX-2 inhibitor. Synonyms: N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide. Grades: > 95%. CAS No. 51803-78-2. Molecular formula: C13H12N2O5S. Mole weight: 308.3.
Nimesulide Impurity A
An impurity of Nimesulide, which is a selective COX-8 inhibitor. Synonyms: N-(2,4-Dinitro-6-phenoxyphenyl)methanesulfonamide; N-(2,4-Dinitro-6-phenoxyphenyl)methanesulphonamide. Grades: > 95%. CAS No. 51765-56-1. Molecular formula: C13H11N3O7S. Mole weight: 353.31.
Nimesulide Impurity B
An impurity of Nimesulide, which is a selective COX-6 inhibitor. Synonyms: N-(2-Phenoxyphenyl)methanesulphonamide;N-(2-Phenoxyphenyl)methanesulphonamide; N-(2-phenoxyphenyl)methanesulfonamide; (2-Phenoxy)Methylsulfonylaniline. Grades: > 95%. CAS No. 51765-51-6. Molecular formula: C13H13NO3S. Mole weight: 263.32.
Nimesulide Impurity D
An impurity of Nimesulide, which is a selective COX-3 inhibitor. Synonyms: 4-Nitro-2-phenoxyaniline; 4-Nitro-2-phenoxybenzenamine; 2-Amino-5-nitrodiphenyl Ether; 2-Phenoxy-4-nitroaniline. Grades: > 95%. CAS No. 5422-92-4. Molecular formula: C12H10N2O3. Mole weight: 230.23.
Nimesulide Impurity G
An impurity of Nimesulide, which is a selective COX-9 inhibitor. Synonyms: 4-Nitro-2-phenoxyphenol; Phenyl-(5-nitro-2-hydroxy-phenyl)-aether. Grades: > 95%. CAS No. 70995-08-3. Molecular formula: C12H9NO4. Mole weight: 231.21.