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Des-Thr(8)-Lanreotide
Des-Thr(8)-Lanreotide is an impurity of Lanreotide, which is a somatostatin analogue with antineoplastic activity. Synonyms: D2Nal-Cys-Tyr-DTrp-Lys-Val-Cys-NH2(Cys2&Cys7 bridge); Des-Thr-Lanreotide; D-2-Naphthylalanyl-L-cystyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cystinamide (Disulfide bridge between cysteines); H-D-2Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-NH2 (Disulfide bridge between cysteines); Lanreotide Impurity F; D2Nal-CY-DTrp-KVC-NH2(Cys2&Cys7 bridge); Des-Thr8-Lanreotide; [Des-Thr8]-Lanreotide. Grade: ≥95%. Molecular formula: C50H62N10O8S2. Mole weight: 995.23.
Des-Thr-NH2-Lanreotide
An impurity of Lanreotide. Lanreotide is a synthetic somatostatin analogue used primarily to treat conditions related to excessive hormone production, such as acromegaly and neuroendocrine tumors. Synonyms: D2Nal-Cys-Tyr-DTrp-Lys-Val-Cys(Cys2&Cys7 bridge); D2Nal-CY-DTrp-KVC(Cys2&Cys7 bridge); H-D-2Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-OH (Disulfide bridge: Cys2-Cys7); 3-(2-Naphthyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteine (2->7)-disulfide; [Des-Thr-NH2]-Lanreotide; [Des-Thr-NH2]8-Lanreotide; Lanreotide acid (1-7). Grade: ≥95%. Molecular formula: C50H61N9O9S2. Mole weight: 996.21.
Destriazolyl Bromo Propiconazole (Mixture of Diastereomers)
An impurities of Propiconazole. Propiconazole is a triazole fungicide inhibiting fungicide due to its binding with and inhibiting the 14-alpha demethylase enzyme from demethylating a precursor to ergosterol. Synonyms: 2-(Bromomethyl)-2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolane; 2-Bromomethyl-2-(2,4-dichlorophenyl)-4-propyldioxolane. Grade: > 95%. CAS No. 60207-89-8. Molecular formula: C13H15BrCl2O2. Mole weight: 354.07.
Destrifluoroethoxy Lansoprazole
An impurity of Lansoprazole, a medication used for the treatment of peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. Synonyms: 2-[(1H-Benzimidazol-2-ylthio)methyl]-3-methyl-4-pyridine. Grade: > 95%. CAS No. 60524-97-2. Molecular formula: C14H13N3OS. Mole weight: 271.34.
Des-Trp5-Eptifibatide
An impurity of Eptifibatide. Eptifibatide is a glycoprotein IIb/IIIa inhibitor used primarily to prevent blood clots in patients with acute coronary syndromes (ACS) and during percutaneous coronary interventions (PCI). Synonyms: Mpr-Har-Gly-Asp-Pro-Cys-NH2(Mpr1&Cys6 bridge); Mpr-Har-GDPC-NH2(Mpr&Cys bridge); deamino-Cys-hArg-Gly-Asp-Pro-Cys-NH2 (Disulfide bridge: Cys1-Cys7); Deamino-cysteinyl-L-homoarginyl-glycyl-L-alpha-aspartyl-L-prolyl-L-cysteinamide (1->7)-disulfide; [Des-Trp]5-Eptifibatide; [Des-Trp5]-Eptifibatide; Des-Trp(5)-Eptifibatide. Grade: ≥95%. Molecular formula: C24H39N9O8S2. Mole weight: 645.75.
Des-Tyr(13)-Semaglutide
Des-Tyr(13)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: (3S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,42S,45S,48S,51S,78R)-51-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-42-(3-amino-3-oxopropyl)-12-benzyl-36-(2-carboxyethyl)-21-(carboxymethyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-33-isobutyl-24-isopropyl-45,48-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,57,66,75,80-icosaoxo-59,62,68,71-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,56,65,74,79-icosaazahexanonacontane-1,78,96-tricarboxylic acid. Molecular formula: C178H282N44O57. Mole weight: 3950.39.
Des-Tyr(14)-Linaclotide
Des-Tyr(14)-Linaclotide is an impurity of Linaclotide, which is a peptide agonist of guanylate cyclase 2C used for the treatment of abdominal pain in patients with irritable bowel syndrome (IBS) associated with constipation. Synonyms: L-cysteinyl-L-cysteinyl-L-alpha-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparagyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteine (1->6),(2->10),(5->13)-tris(disulfide); H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-OH (Disulfide bridge: Cys1-Cys6, Cys2-Cys10, Cys5-Cys13); (3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-amino-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminomethano)-6,29-(methanodithiomethano)pyrrolo[2,1-s][1,2,27,28]tetrathia[5,8,11,14,17,20,23,32,35,38,41]undecaazacyclotritetracontine-15-carboxylic acid; Linaclotide metabolite MM 419447; MM 419447; SP 340; L-Cysteine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-, cyclic (1→6),(2→10),(5→13)-tris(disulfide). CAS No. 1092457-78-7. Molecular formula: C50H70N14O19S6. Mole weight: 1363.55.
Desulfo Glucoraphanin
Glucosinolate analog of Glucoraphanin found in cruciferous vegetables such as broccoli and cauliflower. Synonyms: 1-Thio-1-[N-hydroxy-5-(methylsulfinyl)pentanimidate] β-D-Glucopyranose; 4-Methylsulfinylbutyldesulfoglucosinolate. Grade: 95%. CAS No. 287966-62-5. Molecular formula: C12H23NO7S2. Mole weight: 357.44.
Desulfo Glucoraphanin-d5
Labelled glucosinolate analog of Glucoraphanin found in cruciferous vegetables such as broccoli and cauliflower. Synonyms: 1-Thio-1-[N-hydroxy-5-(methylsulfinyl)pentanimidate]-d5 β-D-Glucopyranose; 4-Methylsulfinylbutyldesulfoglucosinolate-d5. Molecular formula: C12H18D5NO7S2. Mole weight: 362.47.
Desulfo Glucoraphanin-[d5] Tetraacetate
Labelled glucosinolate analog of Glucoraphanin found in cruciferous vegetables such as broccoli and cauliflower. Synonyms: 1-Thio-1-[N-hydroxy-5-(methylsulfinyl)pentanimidate]-d5 β-D-Glucopyranose Tetraacetate; 4-Methylsulfinylbutyldesulfoglucosinolate-d5 Tetraacetate. Molecular formula: C20H26D5NO11S2. Mole weight: 530.62.
Desulfo Glucoraphanin Tetraacetate
Glucosinolate analog of Glucoraphanin found in cruciferous vegetables such as broccoli and cauliflower. Synonyms: 1-Thio-1-[N-hydroxy-5-(methylsulfinyl)pentanimidate] β-D-Glucopyranose Tetraacetate; 4-Methylsulfinylbutyldesulfoglucosinolate Tetraacetate. CAS No. 1453081-22-5. Molecular formula: C20H31NO11S2. Mole weight: 525.59.
Desulfonamide MLN 4924
Intermediate in the preparation of MLN 4924. Synonyms: (1S,2S,4R)-4-[4-[[(1S)-2,3-Dihydro-1H-inden-1-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxy-cyclopentanemethanol. CAS No. 905580-90-7. Molecular formula: C21H24N4O2. Mole weight: 364.44.
Desulpho-CoA
Desulpho-CoA is an essential coenzyme that plays a crucial role in biosynthetic processes involved in the metabolism of sulfur-containing compounds. It acts as a co-substrate in various enzymatic reactions, including the degradation of cysteine and methionine. Desulpho-CoA is particularly valuable in compound for studying and developing researchs related to diseases associated with impaired sulfur metabolism, such as cystathioninuria and homocystinuria. Synonyms: Desulpho-Coenzym A, Sodium salt; Desulfocoenzyme A, Dethiocoenzyme A. Grade: ≥ 95% by HPLC. Molecular formula: C21H36N7O16P3 (free acid). Mole weight: 735.47 (free acid).
Des-Val(10)-Semaglutide
Des-Val(10)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C182H282N44O58. Mole weight: 4014.44.
Des-Val(27)-Semaglutide
Des-Val(27)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Arg-Gly-Arg-Gly-OH. Molecular formula: C182H282N44O58. Mole weight: 4014.44.
Desvenlafaxine
Desvenlafaxine is a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with Ki of 40.2 nM and 558.4 nM, respectively. Uses: Antidepressive agents; neurotransmitter uptake inhibitors. Synonyms: WY 45233 Succinate; WY45233 Succinate; WY-45233 Succinate. Grade: >98%. CAS No. 93413-62-8. Molecular formula: C16H25NO2. Mole weight: 263.38.
Desvenlafaxine benzoate
An impurity of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Synonyms: Phenol, 4-(2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)-, benzoate (1:1). CAS No. 1147940-37-1. Molecular formula: C23H31NO4. Mole weight: 385.5.
Desvenlafaxine fumarate
An impurity of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Synonyms: O-Desmethylvenlafaxine fumarate; 4-(2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol fumarate. Grade: 95%. CAS No. 93414-04-1. Molecular formula: C20H29NO6. Mole weight: 379.45.
Desvenlafaxine Succinate is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively. Synonyms: Pristiq; Desvenlafaxine succinate hydrate; 4-[2-(Dimethylamino)-1-(1-hydroxycy clohexyl)ethyl]phenol succinate; WY 45233 Succinate; WY45233 Succinate; WY-45233 Succinate. Grade: >98%. CAS No. 386750-22-7. Molecular formula: C20H33NO7. Mole weight: 399.48.
DETA NONOate
DETA NONOate is a NO donor. It activates an inward current in cultured rat cerebellar granules cells, increases cGMP production in cultured vascular smooth muscle cells and reduces contractility of cardiac muscle preparations in vitro. Uses: Nitric oxide donors. Synonyms: Diethylamine NONOate; NOC-18; 2,2'-(Hydroxynitrosohydrazino)bis-ethanamine; NSC653048. Grade: ≥98%. CAS No. 146724-94-9. Molecular formula: C4H13N5O2. Mole weight: 163.18.
Deterenol acetate
Deterenol acetate is an impurity of Deterenol. Synonyms: 4-(1-Hydroxy-2-isopropylaminoethyl)-phenol acetate; Paraproterenol acetate; N-Isopropyloctopamineacetate. CAS No. 1644449-83-1. Molecular formula: C13H21NO4. Mole weight: 255.314.
Deterenol Hydrochloride
An effective, nonmydriatic and nonmiotic hypotensive agent with intraocular pressure (IOP) effects similar to epinephrine bitartrate in rhesus monkeys when administered at approx. twice the concentration of epinephrine used clinically. Uses: Adrenergic alpha-agonists. Synonyms: 4-Hydroxy-α-[[(1-methylethyl)amino]methyl]benzenemethanol Hydrochloride. Grade: > 95%. CAS No. 23239-36-3. Molecular formula: C11H18ClNO2. Mole weight: 231.72.
Dethienylethyl Rotigotine
An impurity of Rotigotine.Rotigotine is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS) in Europe and the United States. Grade: > 95%. Molecular formula: C14H22N. Mole weight: 204.34.
Detorubicin
Detorubicin is a semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation. Detorubicin is less toxic than daunorubicin. Check for active clinical trials or closed clinical trials using this agent. Synonyms: MCMC 4777; MCMC4777; MCMC-4777; NSC 292652; NSC-292652; NSC292652; (1S,3S)-3-(Diethoxyacetoxyacetyl)-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl-3-amino-2,36-tridesoxy-alpha-L-lyxo-hexopyranosid. CAS No. 66211-92-5. Molecular formula: C33H39NO14. Mole weight: 673.67.
Detrothyronine
Detrothyronine is an analog of thyroxine. It has been used to reduce cholesterol in blood serum. Synonyms: 3,5,3'-Triiodo-D-thyronine; (2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid. Grade: >95%. CAS No. 5714-8-9. Molecular formula: C15H12I3NO4. Mole weight: 650.97.
Deuterated Poly(1,2-butadiene-d6), end-groups are deuterated
Deuterated Poly(1,2-butadiene-d6), end-groups are deuterated.
Deuterated Poly(1,2-butadiene-d6), end-groups are hydrogen-containing
Deuterated Poly(1,2-butadiene-d6), end-groups are hydrogen-containing.