BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Dephospho CoA | Dephospho CoA is an indispensable enzymatic coenzyme exhibiting multifaceted participation in diverse intricate biochemical processes. With its pivotal involvement in lipid and carbohydrate metabolism, it assumes the vital role of serving as a precursor for the synthesis of acetyl-CoA. Functioning as an augmenter in the elimination of phosphates, it facilitates the degradation and utilization of adipose tissue-derived lipids and saccharides. Synonyms: Dephospho Coenzyme A; 3'-dephospho-CoA; [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-(2-sulfanylethylamino)propyl]amino]butyl] hydrogen phosphate. CAS No. 3633-59-8. Molecular formula: C21H35N7O13P2S. Mole weight: 687.55. |  |
| D-(+)-Epinephrine | A stereoisomer of Epinephrine. Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors. Synonyms: (S)-adrenaline; (+)-epinephrine; 1,2-Benzenediol, 4-[(1S)-1-hydroxy-2-(methylamino)ethyl]-. Grade: 95%. CAS No. 150-05-0. Molecular formula: C9H13NO3. Mole weight: 183.21. | |
| Depropylamino Hydroxy Propafenone | A metabolite of Propafenone.Propafenone is an anti-arrhythmic medication.It can be used for the treatment of illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias. Synonyms: 1-[2-(2,3-Dihydroxypropoxy)phenyl]-3-phenyl-1-propanone. Grade: > 95%. CAS No. 91401-73-9. Molecular formula: C18H20O4. Mole weight: 300.36. | |
| Depropyl Rotigotine | An impurity of Rotigotine.Rotigotine is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS) in Europe and the United States. Grade: > 95%. Molecular formula: C16H19NOS. Mole weight: 273.4. | |
| Depsidellin A | Depsidellin A is an impressive potent compound, serving as an indispensable tool in cutting-edge biomedical research aimed at delving into the intricacies of manifold maladies like cancer, neurological disorders and infectious diseases. CAS No. 204650-54-4. Molecular formula: C33H40O8. Mole weight: 564.66. | |
| Depsidellin B | Depsidellin B is an exceptional compound, used in studying fungal maladies and the most stubborn drug-resistant bacteria. CAS No. 204650-56-6. Molecular formula: C35H44O8. Mole weight: 592.72. | |
| Depyrazine 6,8-Diaminophenyl Varenicline Hydrochloride | Depyrazine 6,8-Diaminophenyl Varenicline Hydrochloride is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Molecular formula: C11H16N3Cl. Mole weight: 225.72. | |
| Depyrazine 6,8-Dinitrophenyl Varenicline | Depyrazine 6,8-Dinitrophenyl Varenicline is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Synonyms: 2,3,4,5-Tetrahydro-6,8-dinitro-1,5-methano-1H-3-benzazepine; 6,8-dinitro-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine. Grade: > 98%. CAS No. 950781-94-9. Molecular formula: C11H11N3O4. Mole weight: 249.22. | |
| Depyrazine 7,8-Dinitro-3-nitroso Varenicline | An impurity of Varenicline. Varenicline is a partial agonist of the α4β2 nicotinic acetylcholine receptor for smoking cessation, which reduces nicotine cravings and withdrawal symptoms by partially stimulating the receptor while blocking nicotine binding. Synonyms: 2,3,4,5-Tetrahydro-7,8-dinitro-3-nitroso-1,5-methano-1H-3-benzazepine; Varenicline Nitroso Impurity 4 (VARENICLINE VRN-5-1600); 7,8-Dinitro-3-nitroso-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine; 4,5-Dinitro-10-nitroso-10-azatricyclo[6.3.1.02,7]dodeca-2,4,6-triene; 7,8-Dinitro-3-nitroso Varenicline. Grade: ≥95%. CAS No. 2803960-63-4. Molecular formula: C11H10N4O5. Mole weight: 278.22. | |
| Depyrazine 7,8-Dinitrophenyl Varenicline | Depyrazine 7,8-Dinitrophenyl Varenicline is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Synonyms: 2,3,4,5-Tetrahydro-7,8-dinitro-1,5-methano-1H-3-benzazepine; 4,5-dinitro-10-azatricyclo[6.3.1.02,7]dodeca-2(7),3,5-trien. Grade: > 98%. CAS No. 230615-08-4. Molecular formula: C11H11N3O4. Mole weight: 249.22. | |
| Depyrazine 7-Nitro-8-aminophenyl N-Trifluoroacetyl Varenicline | Depyrazine 7-Nitro-8-aminophenyl N-Trifluoroacetyl Varenicline is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Synonyms: 1-(7-Amino-1,2,4,5-tetrahydro-8-nitro-1,5-methano-3H-3-benzazepin-3-yl)-2,2,2-trifluoroethanone; 3-(trifluoroacetyl)-8-nitro-2,3,4,5-tetrahydro-1H-1,5-methano-3-benzazepin-7-amine; Varenicline impurity E. Grade: > 98%. CAS No. 950781-89-2. Molecular formula: C13H12F3N3O3. Mole weight: 315.25. | |
| Dequalinium Chloride | Dequalinium Chloride is a PKC inhibitor with IC50 of 7-18 μM, and also a selective blocker of apamin-sensitive K+ channels with IC50 of 1.1 μM. Synonyms: Dequalinium chloride; Dequavagyn; NSC 166454; NSC-166454; NSC166454. Grade: >98%. CAS No. 522-51-0. Molecular formula: C30H40N4.2Cl. Mole weight: 527.57. | |
| Dequalinium chloride hydrate | Dequalinium chloride is a selective blocker of apamin-sensitive K+ channels and inhibitor of XIAP (X-linked inhibitor of apoptosis protein). Synonyms: 1,1'-(Decane-1,10-diyl)bis(4-amino-2-methylquinolin-1-ium) chloride hydrate. CAS No. 1255077-34-9. Molecular formula: C30H42Cl2N4O. Mole weight: 545.59. | |
| Deracoxib | Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class. Deracoxin is a selective cyclooxygenase-2 (COX-2) inhibitor used in the treatment of osteoarthritis in dogs. At low doses, adminsitartion of Deracoxin showed no factors associated with gastrointestinal tract perforation. Synonyms: Deram; Deramaxx; SC 046; SC 46; SC 59046. Grade: >98%. CAS No. 169590-41-4. Molecular formula: C17H14F3N3O3S. Mole weight: 397.37. | |
| Deramciclane | Deramciclane is used for the treatment of a number of anxiety disorders. Deramciclane has a high affinity for 5-HT2A and 5-HT2C receptors. It acts as an antagonist at both receptor subtypes and has inverse agonist properties at the 5-HT2C receptors without direct stimulatory agonist. Uses: Anticonvulsants. Synonyms: Ethanamine, N,N-dimethyl-2-(((1R,2S,4R)-1,7,7-trimethyl-2-phenylbicyclo(2.2.1)hept-2-yl)oxy)-; EGIS-3886. Grade: 95%. CAS No. 120444-71-5. Molecular formula: C20H31NO. Mole weight: 301.47. | |
| Derazantinib dihydrochloride | Derazantinib is an oral fibroblast growth factor receptor (FGFR) inhibitor with antitumor property. FGFR plays a role in the regulation of key cellular behaviors including proliferation, cell differentiation and so on. FGFR dysregulation is considered as a driver in multiple cancers. Derazantinib binds to FGFR and effectively inhibits the activation of FGFR thus can suppress tumorigenesis and tumor growth. Synonyms: Derazantinib hydrochloride; ARQ-087 dihydrochloride; ARQ-087 hydrochloride; ARQ-087 2HCl; ARQ 087 2HCl. CAS No. 1821329-75-2. Molecular formula: C29H31Cl2FN4O. Mole weight: 541.49. | |
| Derazantinib Racemate | Derazantinib Racemate is the racemate of Derazantinib, which is an oral fibroblast growth factor receptor (FGFR) inhibitor with antitumor property. Synonyms: ARQ-087 Racemate; Benzo[h]quinazolin-2-amine, 6-(2-fluorophenyl)-5,6-dihydro-N-[3-[2-[(2-methoxyethyl)amino]ethyl]phenyl]-. Grade: ≥95%. CAS No. 2309668-44-6. Molecular formula: C29H29FN4O. Mole weight: 468.57. | |
| Deriglidole | Deriglidole is a peripheral adrenoceptor antagonist with a high affinity for α2-adrenoceptors. Synonyms: SL 86-0715; (+)-1,2,4,5-Tetrahydro-2-(2-imidazolin-2-yl)-2-propylpyrrolo(3,2,1-hi)indole. CAS No. 122830-14-2. Molecular formula: C16H21N3. Mole weight: 255.36. | |
| D-Eritadenine | D-Eritadenine is an adenosine analog and a potent, reversible inhibitor of S-adenosylhomocysteine hydrolase. Dietary administration of D-eritadenine (50 mg/kg) increases liver microsomal phosphatidylethanolamine concentration and decreases liver microsomal Δ6 desaturase activity and plasma cholesterol levels in rats. Uses: Enzyme inhibitors. Synonyms: (αR,βR)-6-Amino-α,β-dihydroxy-9H-purine-9-butanoic Acid; 4-(6-Amino-9H-purin-9-yl)-4-deoxy-D-erythronic Acid; 4-(6-Aminopurin-9-yl)-4-deoxy-D-erythronic Acid; Lentinacin; Lentysine; 4-(9-Adenyl)-D-erythro-2,3-dihydroxybutyric Acid; Eritadenine; Lentysine; Lentinacin. Grade: ≥95%. CAS No. 23918-98-1. Molecular formula: C9H11N5O4. Mole weight: 253.21. | |
| Dermatan Sulfate (dp10) | Dermatan Sulfate (dp10), a polysaccharide with myriad biomedical applications, has captivated researchers as a therapeutic intervention for osteoarthritis, cancer, and other inflammatory diseases. Through its dynamic enzymatic capabilities, Dermatan Sulfate (dp10) has been identified as a formidable deterrent to cartilage decay, making it an attractive option for those seeking to mitigate the onset and progression of joint degeneration. Synonyms: Dermatan Sulphate Oligosaccharide dp10; Chondroitin sulfate B (dp10); β-Heparin (dp10). Mole weight: 2480. | |
| Dermatan Sulfate (dp12) | Dermatan Sulfate (dp12), a glycosaminoglycan integral to connective tissue and hemostasis, finds therapeutic use in combating maladies ranging from osteoarthritis to heart disease and stroke. This natural compound is likewise valued as a noteworthy constituent for both cosmetic and pharmaceutical products. Synonyms: Dermatan Sulphate Oligosaccharide dp12; Chondroitin sulfate B (dp12); β-Heparin (dp12). Mole weight: 2976. | |
| Dermatan Sulfate (dp14) | Dermatan Sulfate (dp14) is a natural polymer found in individual's body and is essential for maintaining healthy skin. Extensive exploration illustrates its therapeutic properties, rendering it a go-to biomechanical commodity for treating various skin-related maladies, including osteoarthritis and wound healing. Digging deeper, numerous studies reveal its anti-inflammatory and analgesic benefits, offering an optimal solution for pain and inflammation management pertinent to these symptoms. Synonyms: Dermatan Sulphate Oligosaccharide dp14; Chondroitin sulfate B (dp14); β-Heparin (dp14). Mole weight: 3472. | |
| Dermatan Sulfate (dp16) | Dermatan Sulfate (dp16), a complex glycosaminoglycan, is an integral biomolecule essential for the regulation of hemostasis and wound healing in vivo. At the forefront of its highly versatile applications, its immense potential to mitigate vascular disorders such as deep vein thrombosis and skin afflictions like psoriasis through targeted delivery further underscores its value in pharmacotherapy. As a powerful research probe, it facilitates comprehensive exploration of a wide spectrum of pathological mechanisms linked to glycosaminoglycans in biomedical research. Synonyms: Dermatan Sulphate Oligosaccharide dp16; Chondroitin sulfate B (dp16); β-Heparin (dp16). Mole weight: 3968. | |
| Dermatan Sulfate (dp18) | Dermatan sulfate (dp18), a naturally occurring polysaccharide, modulates healthy connective tissues within the human body. Its pivotal significance prompts research studies of its impact on various diseases including osteoarthritis, cardiovascular diseases, cancer, and its biomarker potential for early diagnostic advancements. The utilization of dermatan sulfate's medicinal properties is under constant examination, highlighting its efficacious contribution to the fabric of science and medicine. Synonyms: Dermatan Sulphate Oligosaccharide dp18; Chondroitin sulfate B (dp18); β-Heparin (dp18). Mole weight: 4464. | |
| Dermatan Sulfate (dp20) | Dermatan sulfate (dp20), the extracellular matrix component that participates in diverse physiological phenomena, exhibits novel potential in remedial contexts, such as improved wound healing and mitigated osteoarthritic progressions by fostering cartilage regeneration and moderating inflammation. Its aptitude to synergize with growth factors delineates its propitious candidacy for efficacious drug targeting and tissue engineering deployments. Synonyms: Dermatan Sulphate Oligosaccharide dp20; Chondroitin sulfate B (dp20); β-Heparin (dp20). Mole weight: 4960. | |
| Dermatan Sulfate (dp4) | Dermatan sulfate (dp4) is a remarkably complex polysaccharide derived from various tissues' extracellular matrices. Its potential roles in wound healing and tissue regeneration make it a highly sought after substance. Furthermore, its studied capacity for treating cardiovascular diseases, osteoarthritis, and cancer elevate its value as a subject for biomedical research and development. With its unique structure and multifaceted functional properties, dp4 is a key player in the future of biomedical innovation. Synonyms: Dermatan Sulphate Oligosaccharide dp4; Chondroitin sulfate B (dp4); β-Heparin (dp4). Mole weight: 992. | |
| Dermatan Sulfate (dp6) | Dermatan Sulfate (dp6), a paramount biomedicinal entity, is a key component of the extracellular matrix found in connective tissues. Its regulatory role in cellular behavior is far-reaching, making it a therapeutic emblem of importance. This multifunctional molecule exhibits impressive efficacy against debilitating diseases, specifically osteoarthritis and psoriasis, by alleviating inflammation and initiating tissue repair. The broad utility of Dermatan Sulfate (dp6) extends to boosting drug efficacy and safety in multiple therapeutic modalities. Synonyms: Dermatan Sulphate Oligosaccharide dp6; Chondroitin sulfate B (dp6); β-Heparin (dp6). Mole weight: 1488. | |
| Dermatan Sulfate (dp8) | Dermatan Sulfate (dp8), the glycosaminoglycan utilized in the biomedical industry for its potent anti-inflammatory capabilities. This crucial agent is widely applied as an effective therapy for osteoarthritis and various joint pain disturbances. Furthermore, extensive research has indicated its potential in facilitating wound healing and skin rejuvenation. With Dermatan Sulfate (dp8) at the forefront of bioengineering, the possibilities for groundbreaking advancements are endless. Synonyms: Dermatan Sulphate Oligosaccharide dp8; Chondroitin sulfate B (dp8); β-Heparin (dp8). Mole weight: 1984. | |
| Dermatan sulphate decasaccharide ammonium salt | Dermatan sulphate decasaccharide ammonium salt. Synonyms: Dermatan sulfate decasaccharide ammonium salt. | |
| Dermatan sulphate hexasaccharide ammonium salt | Dermatan sulphate hexasaccharide ammonium salt. Synonyms: Dermatan sulfate hexasaccharide ammonium salt. | |
| Dermatan sulphate octasaccharide ammonium salt | Dermatan sulphate octasaccharide ammonium salt. Synonyms: Dermatan sulfate octasaccharide ammonium salt. | |
| Dermatan sulphate sodium salt | Dermatan sulfate sodium salt, a vital building block of human skin and connective tissue, serves as a telling indicator of multiple illnesses, including cancer, osteoarthritis and cardiovascular disease. With its potential to enhance drug development and treatment efficacy, this dynamic compound proves indispensable to the biomedicine sector. Synonyms: Chondroitin sulfate B sodium salt; b-Heparin; β-Heparin; Dermatan, hydrogen sulfate, sodium salt; Chondroitin sulfate type B sodium salt; Dermatan sulfate sodium salt. CAS No. 54328-33-5. | |
| Dermatan sulphate tetrasaccharide ammonium salt | Dermatan sulphate tetrasaccharide ammonium salt. Synonyms: Dermatan sulfate tetrasaccharide ammonium salt. | |
| Derrubone | Derrubone is a prenylated isoflavone, a type of flavonoid. It was originally isolated from the Indian tree Derris robusta.It has potential application as an inhibitor of Hsp90 to its function as a chaperone protein. Synonyms: 5,7-Dihydroxy-3',4'-methylenedioxy-6-prenylisoflavone. Grade: >98%. CAS No. 22044-58-2. Molecular formula: C21H18O6. Mole weight: 366.37. | |
| Dersimelagon | Dersimelagon is a novel, orally-administered, selective melanocortin-1 receptor (MC1R) agonist that increases skin melanin without sun exposure. Dersimelagon significantly boosted sunlight tolerance in patients with erythropoietic protoporphyria in a multicenter, phase 2, randomized trial. Synonyms: MT-7117; MT7117; MT7117; WHO 10832; WHO-10832; WHO10832. CAS No. 1835256-48-8. Molecular formula: C36H45F4N3O5. Mole weight: 675.77. | |
| D-erythro-MAPP | D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase. It increases intracellular ceramide levels, induces cell cycle arrest at the G0/G1 phase, and inhibits growth of HL-60 promyelocytic leukemia cells in a time- and concentration-dependent manner. Synonyms: (1S,2R-D-erythro-2-N-myristoylamino)-1-phenyl-1-propanol; D-e-MAPP; MAPP, D-erythro. Grade: ≥98%. CAS No. 143492-38-0. Molecular formula: C23H39NO2. Mole weight: 361.6. | |
| D-Erythrono-1,4-lactone | It is a potential substrate of dihydroxy acid dehydratase. Synonyms: (2R,3R)-Butane-2,3,4-triol-1,4-lactone; D-Erythronic acid gamma-lactone; D-Erythronolactone; D-Erythrono-γ-lactone; γ-Lactone D-erythronic Acid; (3R,4R)-3,4-Dihydroxydihydrofuran-2(3H)-one; Erythronic acid-1,4-lactone. Grade: >97%. CAS No. 15667-21-7. Molecular formula: C4H6O4. Mole weight: 118.09. | |
| D-?erythro-?Pentitol, 1,?4-?anhydro-?5-?O-?[bis(4-?methoxyphenyl)?phenylmethyl]?-?2-?deoxy-?1-?C-?1-?naphthalenyl-?, 2-?cyanoethyl bis(1-?methylethyl)?phosphoramidite, (1R)?-(9CI) | D-erythro-Pentitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-1-C-1-naphthalenyl-, 2-cyanoethyl bis(1-methylethyl)phosphoramidite, (1R)-(9CI) emerges as an indispensable phosphoramidite compound within the biomedical industry, specializing in the realm of DNA synthesand alteration. Notably, it assumes a pivotal position in the development of pharmaceutical interventions targeting diverse ailments by facilitating meticulous and regulated modifications of DNA sequences. CAS No. 180611-74-9. Molecular formula: C45H51N2O6P. Mole weight: 746.87. | |
| D-Erythrose | D-Erythrose, a prominent constituent extracted from carbohydrates, possesses tremendous significance in the field of biomedicine. The noteworthy reduction in metabolic disorders like diabetes and galactosemia with the aid of this aqueous solution of 70% purity has been well-established. Moreover, it plays a crucial role in the biosynthesis of nucleotides as well as amino acids. Synonyms: Butanal, 2,3,4-trihydroxy-, [R-(R*,R*)]-; Erythrose, D-; D-(-)-Erythrose. CAS No. 583-50-6. Molecular formula: C4H8O4. Mole weight: 120.10. | |
| D-Erythrose 4-phosphate | D-Erythrose 4-phosphate is an indispensable compound with utilization primarily residing in the synthesis of pyruvic acid and ribose-5-phosphate. Moreover, the influential role of D-Erythrose 4-phosphate extends to the research of specific metabolic disorders. Synonyms: Butanal, 2,3-dihydroxy-4-(phosphonooxy)-, (2R,3R)-; (2R,3R)-2,3-Dihydroxy-4-(phosphonooxy)butanal; Butanal, 2,3-dihydroxy-4-(phosphonooxy)-, [R-(R*,R*)]-; Erythrose, 4-(dihydrogen phosphate), D-; Erythrose, 4-phosphate. CAS No. 585-18-2. Molecular formula: C4H9O7P. Mole weight: 200.08. | |
| D-Erythrose 4-phosphate sodium salt | D-Erythrose 4-phosphate sodium salt is a vital biochemical in the biomedical industry, emerging as an indispensable contributor to the intricate synthesis of carbohydrates and nucleotides. Its multifaceted utility extends to drug development, metabolic disorder exploration, and investigations into glucose metabolism pathways, like the pentose phosphate pathway. CAS No. 103302-15-4. Molecular formula: C4H8NaO7P. Mole weight: 222.07. | |
| D-erythro-Sphingosine | D-erythro-Sphingosine is a natural isomer of sphingosine and acts as an inhibitor of protein kinase C and calmodulin-dependent enzymes with no effects on protein kinase A or myosin light chain kinase. It may stimulate mast cells by activation of protein kinase C. Synonyms: Sphingosine (d18:1); sphingosine; D-Sphingosine; 4-Sphingenine; 2S, 3R(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol; (2S,3R,4E)-2-amino-1,3-octadec-4-enediolsphing-4-enine. Grade: >99%. CAS No. 123-78-4. Molecular formula: C18H37NO2. Mole weight: 299.49. | |
| D-Erythrulose - Aqueous solution | D-Erythrulose is aqueous Solution is an aqueous solution which is an esteemed ketosugar extensively employed in the esteemed biomedical sector. This solution serves as a catalyst, instigating a remarkable interaction with the amino acids delicately residing on the epidermal surface, ultimately resulting in the generation of captivating melanoidins. Synonyms: D-Erythrulose; D-glycero-Tetrulose; (R)-1,3,4-Trihydroxybutan-2-one; Erythrulose, D-; D-Glycero-2-tetrulose; 2-Butanone, 1,3,4-trihydroxy-, (3R)-. CAS No. 496-55-9. Molecular formula: C4H8O4. Mole weight: 120.10. | |
| Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'R)-Aprepitant | Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'R)-Aprepitant is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: (2S,3R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine. CAS No. 1185503-48-3. Molecular formula: C20H18F7NO7. Mole weight: 517.35. | |
| Des-1,2-Diglycine-Terlipressin | An impurity of Terlipressin. Terlipressin is a synthetic vasopressin analogue primarily used to improve kidney function in adults with hepatorenal syndrome (HRS), a condition that causes kidney problems in individuals with severe liver disease. It acts as a vasoconstrictor, predominantly in the splanchnic circulation, which helps increase arterial pressure and reduce portal venous pressure. Synonyms: Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2(Cys2&Cys7 bridge); N-Gly-8-lys-vasopressin; N-Glycyl-8-lysine vasopressin; GCYFQNCPKG-NH2(Cys2&Cys7 bridge); H-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys2-Cys7); Glycyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (2->7)-disulfide; Terlipressin EP Impurity B; Des-1,2-diglycine-terlipressin; Vasopressin, 1-(N-glycylcysteine)-8-lysine; Nα-[Glycyl-Cys]1-[8-Lysine]-vasopressin; N-Glycyl-8-L-lysine-vasopressin; Terlipressin Impurity B. Grade: ≥95%. CAS No. 4235-50-1. Molecular formula: C48H68N14O13S2. Mole weight: 1113.27. | |
| Des-1-Gly-Terlipressin | An impurity of Terlipressin. Terlipressin is a synthetic vasopressin analogue primarily used to improve kidney function in adults with hepatorenal syndrome (HRS), a condition that causes kidney problems in individuals with severe liver disease. It acts as a vasoconstrictor, predominantly in the splanchnic circulation, which helps increase arterial pressure and reduce portal venous pressure. Synonyms: Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2(Cys3&Cys8 bridge); N-(N-Glycylglycyl)-8-L-lysine-vasopressin; Vasopressin, 1-(Glycylglycylcysteine)-8-lysine; Nα-Gly-Gly-8-Lys-vasopressin; GGCYFQNCPKG-NH2(Cys3&Cys8 bridge); N-(N-Gly-Gly)-8-Lys-vasopressin; Triglycyl-desglycine amide lysine vasopressin; N-(N-Glycylglycyl)-8-lysine vasopressin; H-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys3-Cys8); Glycyl-glycyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (3->8)-disulfide; Terlipressin EP Impurity A; Des-1-glycine-terlipressin; des (Gly(1)-Terlipressin. Grade: ≥95%. CAS No. 14943-47-6. Molecular formula: C50H71N15O14S2. Mole weight: 1170.33. | |
| Des(2-methylbutyryl) 6'-epipravastatin | An impurity of Pravastatin. Pravastatin is a member of the drug class of statins. It can be used for lowering cholesterol and preventing cardiovascular disease. Synonyms: (βR,δR,1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6,8-tetrahydroxy-2-methyl-1-naphthaleneheptanoic acid; (3R,5R)-7-((1S,2S,6R,8S,8aR)-6,8-Dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)-3,5-dihydroxyheptanoic acid; Pravastatin Impurity F (6'-epimer); Des(2-methylbutanoyl) 6'-epipravastatin. Grade: >95%. CAS No. 776294-80-5. Molecular formula: C18H28O6. Mole weight: 340.41. | |
| Des(2-methylbutyryl) Lovastatin Hydroxy Acid Sodium Salt | An impurity of Lovastatin. Lovastatin is an HMG CoA reductase inhibitor used to treat high blood cholesterol. Synonyms: 3,5-Dihydroxy-7-(8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl)heptenoate Acid Sodium Salt; [1S-[1α(βS*,δS*),2β,6β,8β,8aα]]-1,2,6,7,8,8a-hexahydro-β,δ,8-trihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid Monosodium Salt. Grade: > 95%. CAS No. 132294-94-1. Molecular formula: C19H29O5Na. Mole weight: 360.42. | |
| Des[3-[[(1-Carboxymethyl)cyclopropyl]methyl]thio]-2-propenyl Montelukast Mesylate | Des[3-[[(1-Carboxymethyl)cyclopropyl]methyl]thio]-2-propenyl Montelukast Mesylate is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: 2-[(2E)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-2-propen-1-yl]-α,α-dimethyl-benzenemethanol Methanesulfonate. CAS No. 1187586-82-8. Molecular formula: C30H30ClNO4S. Mole weight: 536.08. | |
| Des-(32,31)-Thr,Pro-Calcitonin | Des-(32,31)-Thr,Pro-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-NH2 (Disulfide bond between Cys1 and Cys7); L-cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-glycinamide (1->7)-disulfide. Molecular formula: C136H226N42O45S2. Mole weight: 3233.67. | |
| Des-(32,31)-Thr,Pro Calcitonin Acid | Des-(32,31)-Thr,Pro Calcitonin Acid is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: Des(32,31)-Thr,Pro-OH Calcitonin; H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-OH (Disulfide bond between Cys1 and Cys7); L-cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-glycine (1->7)-disulfide. Molecular formula: C136H225N41O46S2. Mole weight: 3234.66. | |
| Des-(3-(Pyridin-2-ylamino)propanoate)Dabigatran Ethyl Ester | Des-(3-(Pyridin-2-ylamino)propanoate)Dabigatran Ethyl Ester is an impurity of Dabigatran. Dabigatran is a very potent anticoagulant, in which the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Synonyms: Ethyl 2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-1H-benzo[d]imidazole-5-carboxylate. CAS No. 1408238-41-4. Molecular formula: C19H21N5O2. Mole weight: 351.41. | |
| Des-[(4-Amino-2,3,6-trideoxy-hexapyranosyl)oxy)-1-methyl] 2-Carboxylate Doxorubicin | Des-[(4-Amino-2,3,6-trideoxy-hexapyranosyl)oxy)-1-methyl] 2-Carboxylate Doxorubicin is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: Doxorubicin Hydrochloride Impurity 5. Molecular formula: C20H12O7. Mole weight: 364.31. | |
| Des-(4-chloro-3-trifluoromethyl)-4-(methyl-4-hydroxypicolinate) Sorafenib | Des-(4-chloro-3-trifluoromethyl)-4-(methyl-4-hydroxypicolinate) Sorafenib is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: 4-[4-[[[[4-[[2-[(Methylamino)carbonyl]-4-pyridinyl]oxy]phenyl]amino]carbonyl]amino]phenoxy]-methyl ester-2-pyridinecarboxylic Acid; Sorafenib Impurity C; Sorafenib Impurity 6. Grade: > 98%. CAS No. 2204442-52-2. Molecular formula: C27H23N5O6. Mole weight: 513.50. | |
| Des(4-cyclohexyl-L-proline) Fosinopril Acetic Acid | Des(4-cyclohexyl-L-proline) Fosinopril Acetic Acid. Synonyms: [(R)-[(1S)-2-Methyl-1-(i-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl] Acetic acid; 2-[(R)-[(1S)-2-Methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetic Acid. Grade: > 95%. CAS No. 128948-00-5. Molecular formula: C19H29O6P. Mole weight: 384.41. | |
| Des-4-fluorobenzyl Mosapride | Des-4-fluorobenzyl Mosapride is an impurity of Mosapride. Mosapride is a 5-HT4 receptor agonist and 5-HT3 receptor antagonist. It is used as a gastroprokinetic agent. Synonyms: Des-p-fluorobenzyl mosapride; Mosapride Impurity 5; 4-amino-5-chloro-2-ethoxy-N-((2-morpholinyl)methyl)benzamide. Grade: 95%. CAS No. 152013-26-8. Molecular formula: C14H20ClN3O3. Mole weight: 313.79. | |
| Des-5'-chloro-4-fluorobenzyl Mosapride | Des-5'-chloro-4-fluorobenzyl Mosapride is an intermediate of Mosapride, which is a selective agonist of 5-HT4 receptor, could be used as an astroprokinetic agent. It is also found to be a 5-HT3 receptor antagonist. Uses: Intermediate in the preparation of mosapride and its metabolites. Synonyms: 4-Amino-2-ethoxy-N-(2-morpholinylmethyl)benzamide; Benzamide, 4-amino-2-ethoxy-N-(2-morpholinylmethyl)-. Grade: 98%. CAS No. 170799-30-1. Molecular formula: C14H21N3O3. Mole weight: 279.33. | |
| Des(5-methylpyrazinecarbonyl) Glipizide | Des(5-methylpyrazinecarbonyl) Glipizide is an impurity formed during the synthesis of Glipizide. Glipizide is an oral rapid- and short-acting anti-diabetic drug from the sulfonylurea class. Synonyms: 4-(2-Aminoethyl)-N-(cyclohexylcarbamoyl)benzene-1-sulfonamide; 1-[[p-(2-Aminoethyl)phenyl]sulfonyl]-3-cyclohexylurea. CAS No. 2015-16-9. Molecular formula: C15H23N3O3S. Mole weight: 325.43. | |
| Des-(5-(threo-3-hydroxy-L-ornithine)) Caspofungin Acetate | Des-(5-(threo-3-hydroxy-L-ornithine)) Caspofungin Acetate is an impurity of Caspofungin acetate, which is an essential component of the cell wall of filamentous fungi. Synonyms: Caspofungin Acetate Impurity 7; Caspofungin Impurity 5; Pneumocandin B0, 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]pneumocandin B0. CAS No. 1404083-47-1. Molecular formula: C52H86N10O16. Mole weight: 1107.29. | |
| Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib | Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib is an intermediate in the preparation of Dasatinib metabolite, used in the treatment of cancers and immune diseases. Synonyms: N-[2-Chloro-6-(hydroxymethyl)phenyl]-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide. Grade: > 95%. CAS No. 910297-71-1. Molecular formula: C16H13Cl2N5O2S. Mole weight: 410.28. | |
| Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro-O-pivalate Dasatinib | Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro-O-pivalate Dasatinib is an intermediate in the preparation of Dasatinib metabolite, used in the treatment of cancers and immune diseases. Synonyms: 2,2-Dimethyl-propanoic Acid [3-Chloro-2-[[[2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolyl]carbonyl]amino]phenyl]methyl Ester. Grade: > 95%. CAS No. 910297-70-0. Molecular formula: C21H21Cl2N5O3S. Mole weight: 494.39. | |
| Des-Acety-Cetrorelix | Des-Acety-Cetrorelix is an impurity of Cetrorelix, which is a gonadotropin-releasing hormone antagonist used in the treatment of prostate and breast cancers. Synonyms: D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Alanine amide; Cetrorelix Impurity-9; Des-Ac-Cetrorelix; 3-(2-Naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; (S)-N-((R)-1-amino-1-oxopropan-2-yl)-1-((2S,5S,8R,11S,14S,17R,20R,23R)-23-amino-20-(4-chlorobenzyl)-2-(3-((diaminomethylene)amino)propyl)-11-(4-hydroxybenzyl)-14-(hydroxymethyl)-5-isobutyl-24-(naphthalen-2-yl)-4,7,10,13,16,19,22-heptaoxo-17-(pyridin-3-ylmethyl)-8-(3-ureidopropyl)-3,6,9,12,15,18,21-heptaazatetracosanoyl)pyrrolidine-2-carboxamide; D-Alaninamide, 3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-. CAS No. 121081-09-2. Molecular formula: C68H90ClN17O13. Mole weight: 1389.02. | |
| Desacetyl-7-ACA lactone | Desacetyl-7-ACA lactone is a lactone derivative of 7-Aminocephalosporanic acid, a fundamental building block in the synthesis of cephalosporin antibiotics. Synonyms: (5aR,6R)-6-Amino-5a,6-dihydro-3H,7H-Azeto[2,1-b]furo[3,4-d][1,3]thiazine-1,7(4H)-dione; (5aR-trans)-6-amino-5a,6-dihydro-3H,7H-Azeto[2,1-b]furo[3,4-d][1,3]thiazine-1,7(4H)-dione. Grade: > 95%. CAS No. 184696-69-3. Molecular formula: C8H8N2O3S. Mole weight: 212.23. | |
| Desacetyl acetaminophen glutathione | Desacetyl Acetaminophen Glutathione is a hepatic metabolite of Acetaminophen, which is a selective COX-2 inhibitor used as an antipyretic, analgesic, and anti-inflammatory agent. Uses: The hepatic metabolite of p-aminophenol. the aminophenol glutathione s-conjugates formed induce p-aminophenol nephrotoxicity by a pathway dependent on γ-glutamyl transpeptidase. Synonyms: N-[S-(5-Amino-2-hydroxyphenyl)-N-L-γ-glutamyl-L-cysteinyl]glycine; Glycine, N-[S-(5-amino-2-hydroxyphenyl)-N-L-γ-glutamyl-L-cysteinyl]-. Grade: 95%. CAS No. 129762-76-1. Molecular formula: C16H22N4O7S. Mole weight: 414.43. | |
| Des-acetyl Apremilast | Des-acetyl Apremilast is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: 4-Amino-2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione; (S)-4-amino-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione. CAS No. 635705-72-5. Molecular formula: C20H22N2O6S. Mole weight: 418.46. | |
| Desacetyl bisacodyl | An impurity of Bisacodyl, which is a stimulant laxative belonging to the diphenylmethane family. It works by enhancing colonic motility and increasing stool water content. It needs to be converted into the active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM) in the gut to achieve its laxative effect. Uses: The active form of bisacodyl. cathartic. Synonyms: 4,4'-[(Pyridin-2-yl)methylene]diphenol; Deacetylbisacodyl; Dihydroxydiphenyl-pyridyl methane; DDPM; p,p'-(2-Pyridylmethylene)bisphenol; 4,4'-(2-Pyridinylmethylene)bisphenol; Deacetyl Bisacodyl; 4,4'-(2-Pyridylmethylene)diphenol; 4,4'-Dihydroxydiphenyl(2-pyridyl)methane; Bis(4-hydroxyphenyl)(2-pyridyl)methane; Bisacodyl EP Impurity A; Bisacodyl Impurity A; Picosulfate EP Impurity B; Sodium Picosulfate EP Impurity B; USP Bisacodyl Related Compound A; 4,4'-(Pyridin-2-ylmethylene)diphenol; Bisacodyl USP Related Compound A; Bisacodyl Related Compound A. Grade: 95%. CAS No. 603-41-8. Molecular formula: C18H15NO2. Mole weight: 277.32. | |
| Desacetyl Bisacodyl β-D-Glucuronide | Desacetyl-Bisacodyl β-D-glucuronide is a metabolite of Bisacodyl, which is a drug used primarily as a laxative to treat constipation. Uses: The glucuronide metabolite of desacetyl bisacodyl. Synonyms: 4-[(4-Hydroxyphenyl)-2-pyridinylmethyl]phenyl β-D-glucopyranosiduronic acid; α-(p-Hydroxyphenyl)-α-2-pyridyl-p-tolyl β-D-glucosiduronic acid; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(4-((4-hydroxyphenyl)(pyridin-2-yl)methyl)phenoxy)tetrahydro-2H-pyran-2-carboxylic acid; Desacetyl-Bisacodyl β-D-glucuronidel; Desacetyl Bisacodyl 2-D-Glucuronide; Bisacodyl Desacetyl β-D-Glucuronide. Grade: ≥98%. CAS No. 31050-47-2. Molecular formula: C24H23NO8. Mole weight: 453.44. | |
| Desacetyl Cefathiamidine | Desacetyl Cefathiamidine is a derivative of Cefathiamidine; an antibacterial agent that exhibits a broad spectrum of bactericidal activity against gram-positive bacteria. Synonyms: (6R,7R)-3-(Hydroxymethyl)-7-[[2-[[[(1-methylethyl)amino][(1-methylethyl)imino]methyl]thio]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid. Grade: > 95%. CAS No. 958001-61-1. Molecular formula: C17H26N4O5S2. Mole weight: 430.55. | |
| Desacetyl Cephapirin Sodium Salt | Desacetyl Cephapirin Sodium Salt is an impurity of cefapirin sodium which is a cephalosporin antibiotic agent. Synonyms: (6R,7R)-3-(Hydroxymethyl)-8-oxo-7-[[2-(4-pyridinylthio)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt; Deacetylcephapirin Sodium Salt; (6R-trans)-3-(Hydroxymethyl)-8-oxo-7-[[(4-pyridinylthio)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt. Grade: > 95%. CAS No. 104557-24-6. Molecular formula: C15H14N3NaO5S2. Mole weight: 403.41. | |
| Desacetylcinobufotalin | Desacetylcinobufotalin is apoptosis inducer. shows the inhibition effect to HepG2 cells (IC50 =0.0279μmol/ml). Uses: Apoptosis inducer. Synonyms: De-O-acetylcinobufotalin; 14,15β-Epoxy-3β,5,16β-trihydroxy-5β-bufa-20,22-dienolide. Grade: ≥98%. CAS No. 4099-30-3. Molecular formula: C24H32O6. Mole weight: 416.51. | |
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