BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Decitabine impurity 7 (Mixture of α/β isomers) | 2-Deoxy-D-erythro-pentopyranosyl chloride bis(4-methylbenzoate) is an impurity of Decitabine, a DNA hypomethylating agent that is used to treat various forms of cancer, such as myelogeneous leukemia and metastatic lung cancerBy inhibiting DNA methyltransferase, Decitabine silences the tumour suppressor genes and, consequently, "normalizing" gene expression in cancerous cells. Synonyms: 2-Deoxy-D-erythro-pentopyranosyl Chloride Bis(4-methylbenzoate). Grade: > 95%. CAS No. 20535-28-8. Molecular formula: C21H21ClO5. Mole weight: 388.84. |  |
| Decitabine Impurity 8 | Decitabine Impurity 8 is an impurity of Decitabine, which is a nucleic acid synthesis inhibitor for the treatment of myelodysplastic syndromes and acute myeloid leukemia (AML). Synonyms: 2-Deoxy-D-β-ribopyranosyl-5-azacytosine; 4-Amino-1-(2-deoxy-β-D-erythro-pentopyranosyl)-1,3,5-triazin-2(1H)-one; 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-β-D-erythro-pentopyranosyl)-. Grade: ≥95%. CAS No. 157771-78-3. Molecular formula: C8H12N4O4. Mole weight: 228.21. | |
| Decitabine Impurity 9 | Decitabine Impurity 9 is an impurity of Decitabine, which is a potent inhibitor of DNA methylation. Molecular formula: C20H15Cl2NO6. Mole weight: 436.24. | |
| Decitabine Related Compound A (Mixture of Isomers) | Decitabine Related Compound A (Mixture of Isomers) is a isomeric entities that bear a remarkable kinship to Decitabine, an invaluable therapeutic agent efficaciously employed in studying myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Grade: > 95%. CAS No. 1019659-87-0. Molecular formula: C21H18Cl2O7. Mole weight: 453.28. | |
| Decitabine Related Compound B | 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one is a derivative of β-Decitabine which is used as cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines. Synonyms: 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one; β-Decitabine-3',5'-bis(4-chlorobenzoate). Grade: > 95%. CAS No. 1034301-08-0. Molecular formula: C22H18Cl2N4O6. Mole weight: 505.31. | |
| Decitabine Related Compound C | 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one is a derivative of α-Decitabine which is shown to inhibit DNA methylation resulting in an effective anticancer agent. Synonyms: 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one. Grade: > 95%. CAS No. 1140891-02-6. Molecular formula: C22H18Cl2N4O6. Mole weight: 505.31. | |
| Decloxizine hydrochloride | The hydrochloride salt form of Decloxizine, a hydroxyzine analogue, is a histamine 1 receptor antagonist and often known as an impurity of Hydroxyzine. Uses: The hydrochloride salt form of decloxizine is a histamine 1 receptor antagonist and often known as an impurity of hydroxyzine. Synonyms: 2-[2-[4-(Diphenylmethyl)-1-piperazinyl]ethoxy]ethanol Hydrochloride; 1-[2-(2-Hydroxyethoxy)ethyl]-4-α-phenylbenzyldiethylenediamine Dihydrochloride; Autokar; Hydroxydiethylphenamine; Rescupal; UCB 1402; UCB1402; UCB-1402. Grade: 95%. CAS No. 13073-96-6. Molecular formula: C21H28N2O2?2ClH. Mole weight: 413.39. | |
| Decyl 2-acetamido-2-deoxy-b-D-glucopyranoside | Decyl 2-acetamido-2-deoxy-β-D-glucopyranoside is a non-ionic surfactant derived from glucose, featuring a decyl (C10) alkyl chain attached to 2-acetamido-2-deoxy-β-D-glucose. Known for its mild properties, this surfactant is widely used in biochemical research to solubilize membrane proteins without denaturing them, aiding in the study of protein-lipid interactions and membrane dynamics. In pharmaceuticals, it serves as an excipient to enhance the solubility and bioavailability of hydrophobic drugs and is utilized in drug delivery systems. Additionally, it is employed in cosmetics and personal care products, such as mild cleansers and shampoos, due to its gentle surfactant properties and compatibility with skin and hair, making it suitable for sensitive applications. Its non-ionic nature and ability to preserve protein functionality make it an invaluable tool in various scientific and industrial applications. Synonyms: Decyl 2-(acetylamino)-2-deoxy-β-D-glucopyranoside; N-((2R,3R,4R,5S,6R)-2-(Decyloxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide. CAS No. 147025-05-6. Molecular formula: C18H35NO6. Mole weight: 361.47. | |
| Decyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside | Decyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is a biomedicine product utilized in the treatment of various diseases. With its potent antimicrobial properties, it is commonly employed in the development of novel antibiotics targeting drug-resistant bacteria. Moreover, this compound plays a crucial role in the development of advanced therapies for infectious diseases and provides a potential solution to combatting bacterial infections that have become resistant to traditional antibiotics. Synonyms: β-D-Glucopyranoside, decyl 2-(acetylamino)-2-deoxy-, 3,4,6-triacetate; Decyl-2-(acetylamino)-2-deoxy-3,4,6-triacetate-β-D-glucopyranoside; (2R,3S,4R,5R,6R)-5-Acetamido-2-(acetoxymethyl)-6-(decyloxy)tetrahydro-2H-pyran-3,4-diyl diacetate. CAS No. 135198-04-8. Molecular formula: C24H41NO9. Mole weight: 487.58. | |
| Decyl 4-O-b-D-lactopyranosyl-b-D-lactopyranoside | Decyl 4-O-b-D-lactopyranosyl-b-D-lactopyranoside is a paramount constituent extensively employed in the biomedical sector for the research of diverse cutaneous anomalies and ailments. Synonyms: Lac b(1-4)Lac-b-C10. CAS No. 1858224-00-6. Molecular formula: C34H62O21. Mole weight: 806.84. | |
| Decyl a-D-glucopyranoside | Decyl α-D-glucopyranoside, an essential biochemical compound, finds extensive applications in the burgeoning biomedicine industry. Possessing remarkable surfactant properties, it serves as a delicate detergent in the realm of cellular and molecular biology investigations. This exquisite product assumes a pivotal role in protein formulation, membrane protein analysis, as well as the solubilization of hydrophobic entities. Notably, owing to its outstanding biocompatibility and negligible toxicity, Decyl α-D-glucopyranoside enjoys widespread employment in the realm of lysosomal storage disease examination and certain drug delivery systems. Synonyms: Decyl a-glucoside. CAS No. 29781-81-5. Molecular formula: C16H32O6. Mole weight: 320.42. | |
| Decyl a-D-maltopyranoside | Decyl a-D-maltopyranoside is a surfactant commonly used in the biomedical industry for various purposes. With excellent solubility and mildness, it finds applications in drug delivery systems, protein analysis and cell culture. Additionally, Decyl a-D-maltopyranoside is particularly employed in the research of neurodegenerative diseases, such as Alzheimer's and Parkinson's. Synonyms: Decyl 4-O-α-D-glucopyranosyl-α-D-glucopyranoside; Decyl α-D-maltopyranoside; Decyl alpha-maltoside; n-Decyl-α-D-Maltopyranoside; (2R,3R,4S,5S,6R)-2-(((2R,3S,4R,5R,6S)-6-(Decyloxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 168037-12-5. Molecular formula: C22H42O11. Mole weight: 482.56. | |
| Decyl a-L-rhamnopyranoside | Decyl a-L-rhamnopyranoside is a compound product used in the research of various diseases acting as a surfactant and is commonly used in drug delivery systems and gene therapy. This compound can enhance the stability and solubility of certain drugs, making it a valuable tool in the formulation of pharmaceutical products. Its applications also extend to cell culture and protein research where it aids in the solubilization and purification of proteins. Synonyms: Decyl rhamnoside; decyl 6-deoxy-alpha-L-manno-hexopyranoside; Decyl 6-deoxy-α-L-mannopyranoside. CAS No. 1621700-82-0. Molecular formula: C16H32O5. Mole weight: 304.42. | |
| Decyl b-D-glucopyranoside | Decyl b-D-glucopyranoside, a non-ionic surfactant widely utilized in the biomedicine industry, has gained significant attention for its prowess in solubilizing and extracting membrane proteins. Besides its utility in the formulation of drug delivery systems and vaccine research, its non-toxic nature coupled with its ability to form stable complexes make it a promising candidate for treating life-threatening ailments like cancer and neurological disorders. Synonyms: Decyl β-D-glucopyranoside; 1-O-Decyl-β-D-glucopyranoside; AG 10; AG 10 (carbohydrate); APG 10; Decyl glucoside; Decyl β-D-glucoside; Decyl β-glucopyranoside; Decyl β-glucoside; n-Decyl β-D-glucopyranoside; n-Decyl-β-glucoside; Oramix NS 10; Plantacare 818; Plantaren PS 100; Plantaren W 2000. CAS No. 58846-77-8. Molecular formula: C16H32O6. Mole weight: 320.42. | |
| Decyl b-D-maltopyranoside | Decyl b-D-maltopyranoside is a nonionic surfactant that is commonly used to solubilize and stabilize membrane proteins. Synonyms: Decyl maltoside; Decyl 4-O-α-D-glucopyranosyl-β-D-glucopyranoside; 1-Decyl β-D-maltoside; 1-O-Decyl-β-D-maltoside; D 382; Decyl β-D-maltopyranoside; Decyl β-D-maltoside; Decyl β-maltopyranoside; Decyl-β-maltoside; n-Decyl β-D-maltoside; n-Decyl-β-D-maltopyranoside. Grade: >99%. CAS No. 82494-09-5. Molecular formula: C22H42O11. Mole weight: 482.56. | |
| Decyl b-D-thioglucopyranoside | Decyl b-D-thioglucopyranoside is a versatile compound, offers immense potential in the research of a wide range of diseases associated with cell surface glycoconjugates. This non-ionic detergent, highly prevalent in biochemistry and molecular biology research, is predominantly utilized for the isolation, purification and solubilization of membrane proteins. Moreover, it serves as a crucial component in the investigation of glycoproteins, lectins and diverse glycoconjugates. Synonyms: Decyl 1-thio-β-D-glucopyranoside; (2S,3R,4S,5S,6R)-2-(Decylthio)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; Decyl β-D-thioglucopyranoside; Decyl-β-D-1-thioglucopyranoside. CAS No. 98854-16-1. Molecular formula: C16H32O5S. Mole weight: 336.49. | |
| Decyl b-D-thiomaltopyranoside | Decyl b-D-thiomaltopyranoside, a widely applied biomedicine product boasting multifaceted pharmaceutical industry usage, stands as a pivotal surfactant in both drug formulations and research endeavors. Its unmatched ability to solubilize hydrophobic drugs and facilitate their targeted transportation renders it indispensable. Synonyms: n-Decyl b-D-thiomaltoside; Decyl 4-O-α-D-glucopyranosyl-1-thio-β-D-glucopyranoside; 1-S-Decyl β-D-thiomaltopyranoside; Decyl-beta-D-1-thiomaltopyranoside. CAS No. 148565-56-4. Molecular formula: C22H42O10S. Mole weight: 498.63. | |
| Decyl Glucose Neopentyl Glycol | Decyl Glucose Neopentyl Glycol is a compound used in the research of various skin disorders and conditions helping to study symptoms associated with dryness, irritation and inflammation. Synonyms: 2,2-Dioctylpropane-1,3-bis b-D-glucopyranoside; 2,2-Dioctyl-1,3-propanediyl bis[β-D-glucopyranoside]. Grade: 98%. CAS No. 1423314-52-6. Molecular formula: C31H60O12. Mole weight: 624.81. | |
| Decyl glucoside | Decyl glucoside is a biocompatible non-ionic surfactant used in the biomedical industry. It is commonly employed as an excipient in pharmaceutical formulations, especially for topical applications. With its excellent ability to solubilize hydrophobic drugs, decyl glucoside enhances drug delivery and bioavailability. Synonyms: D-Glucose decyl octyl ether, oligomeric; Capryl/Caprylyl Glycoside. CAS No. 68515-73-1. Molecular formula: C16H32O6. Mole weight: 320.22. | |
| Decyl maltose neopentyl glycol | Decyl maltose neopentyl glycol is a vital constituent extensively employed in the biomedical sector, exhibiting inhibitory efficacy in diverse drugs development. It is an indispensable element in studying ailments like cancer, diabetes and cardiovascular disorders. Synonyms: 2,2-Dioctylpropane-1,3-bis b-D-maltopyranoside; Decyl MNG; 2,2-Dioctyl-1,3-propanediyl bis[4-O-α-D-glucopyranosyl-β-D-glucopyranoside; (2R,2'R,3S,3'S,4S,4'S,5R,5'R,6R,6'R)-6,6'-(((2R,2'R,3S,3'S,4R,4'R,5R,5'R,6R,6'R)-((2,2-dioctylpropane-1,3-diyl)bis(oxy))bis(4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-6,3-diyl))bis(oxy))bis(2-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol); 2-{[(4-O-Alpha-D-Glucopyranosyl-Beta-D-Glucopyranosyl)oxy]methyl}-2-Octyldecyl 4-O-Alpha-D-Glucopyranosyl-Beta-D-Glucopyranoside. Grade: >95%. CAS No. 1257852-99-5. Molecular formula: C43H80O22. Mole weight: 949.08. | |
| Decyl Methyl Ether | Decyl Methyl Ether is a fragrance/Aroma compound with a fresh scent. Decyl Methyl Ether is a fatty ether used as a possible diesel fuel extender. Synonyms: 1-Methoxydecane; Methyl Decyl Ether; Methyl n-Decyl Ether. Grade: > 95%. CAS No. 7289-52-3. Molecular formula: C11H24O. Mole weight: 172.31. | |
| Decynium 22 | Decynium 22 is a potent inhibitor of PMAT and has been found to exhibit activities in inducing apoptosis in cerebellar granule neurons (CGNs). Synonyms: 1-Ethyl-2-[(1-ethyl-2(1H)-quinolinylidene)methyl]quinolinium iodide. Grade: ≥98% by HPLC. CAS No. 977-96-8. Molecular formula: C23H23IN2. Mole weight: 454.35. | |
| De(diethylaminoethyl-5-iodo) Amiodarone | An impurity of Amiodarone, an antiarrhythmic medication used to treat ventricular tachycardia or ventricular fibrillation. Synonyms: Amiodarone EP Impurity F; Amiodarone Impurity F; (2-Butylbenzofuran-3-yl)(4-hydroxy-3-iodophenyl)methanone; Amiodarone Hydrochloride EP Impurity F; Amiodarone USP RC F; Amiodarone Impurity F; 4-[(2-Butyl-1-benzofuran-3-yl)carbonyl]-2-iodophenol; (2-Butyl-3-benzofuranyl)(4-hydroxy-3-iodophenyl)methanone; L 6424; Amiodarone related compound F; Amiodarone USP Related Compound F; USP Amiodarone Related Compound F. Grade: >95%. CAS No. 147030-50-0. Molecular formula: C19H17IO3. Mole weight: 420.25. | |
| Dedimethyl Dibromo Memantine | Dedimethyl Dibromo Memantine is a di-bromo derivative of Memantine, which is a medication used to slow the progression of moderate-to-severe Alzheimer's disease. Synonyms: 1,3-Dibromo Adamantamine; 3,5-Dibromo-1-adamantanamine; Tricyclo[3.3.1.13,7]decan-1-amine, 3,5-dibromo-. Grade: 98%. CAS No. 1797133-04-0. Molecular formula: C10H15Br2N. Mole weight: 309.04. | |
| Dedimethyl Tribromo Memantine Hydrobromide | Dedimethyl Tribromo Memantine is a tri-bromo derivative of Memantine, which is a medication used to slow the progression of moderate-to-severe Alzheimer's disease. Synonyms: Tricyclo[3.3.1.13,7]decan-1-amine, 3,5,7-tribromo-, hydrobromide (1:1); 3,5,7-Tribromo-1-adamantanamine hydrobromide (1:1); 1,3,5-Tribromo Adamantamine Hydrobromide. Grade: 98%. CAS No. 1797824-66-8. Molecular formula: C10H15Br4N. Mole weight: 468.85. | |
| Defactinib | Defactinib, also known as VS-6063 and PF-04554878, is an orally bioavailable, small-molecule focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. FAK inhibitor PF-04554878 inhibits FAK, which may prevent the integrin-mediated activation of several downstream signal transduction pathways, including ERK, JNK/MAPK and PI3K/Akt, thus inhibiting tumor cell migration, proliferation and survival. The tyrosine kinase FAK is , a signal transducer for integrins that is upregulated in many tumor cell types and is involved in tumor cell invasion, migration and proliferation. Synonyms: N-methyl-4-((4-(((3-(N-methylmethylsulfonamido)pyrazin-2-yl)methyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)benzamide; VS6063; VS 6063; VS-6063; PF04554878; PF-04554878; PF 04554878; PF4554878; PF-4554878. Grade: >98%. CAS No. 1073154-85-4. Molecular formula: C20H21F3N8O3S. Mole weight: 510.496. | |
| Defactinib hydrochloride | Defactinib HCl is a potent FAK phosphorylation inhibitor, overcoming YB-1-mediated paclitaxel resistance by an AKT-dependent pathway. Synonyms: N-Methyl-4-((4-(((3-(methyl(methylsulfonyl)amino)pyrazin-2-yl)methyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)benzamide monohydrochloride; Defactinib hydrochloride; Defactinib HCl; VS6063; VS 6063; VS-6063; PF04554878; PF-04554878; PF 04554878; PF4554878; PF-4554878; PF4554878. Grade: >98%. CAS No. 1073160-26-5. Molecular formula: C20H22ClF3N8O3S. Mole weight: 546.95. | |
| Defensamide | Defensamide (MHP) can modulate the innate epidermal immune response by potentiating SPHK1 activity and inducing cAMP production. It is an activator of sphingosine kinase (SPHK1). Synonyms: MHP; N-Hexanoyltyrosine methyl ester; UNII-8GJP2KSJ0T; 8GJP2KSJ0T. CAS No. 1104874-94-3. Molecular formula: C16H23NO4. Mole weight: 293.36. | |
| Defensin HNP-1 (human) trifluoroacetate salt | Defensin HNP-1 is a peptide secreted by polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It completely inhibits secretion of the exotoxin superantigen TSS toxin-1 (TSST-1) from S. aureus when used at a concentration of 50 ng/ml and inhibits anthrax lethal toxin. Synonyms: DEFA1 Protein; α-Defensin 1; Human Neutrophil Peptide 1; Neutrophil Defensin 1. Grade: ≥95%. Molecular formula: C150H222N44O38S6·xCF3COOH. Mole weight: 3442.04. | |
| Defensin HNP-2 (human) trifluoroacetate salt | Defensin HNP-2 is a peptide with antimicrobial properties that is secreted by human polymorphonuclear leukocytes (PMNs). Defensin HNP-2 binds to recombinant HIV-1 envelope glycoprotein gp120 and human CD4. Synonyms: DEFA2 Protein; α-Defensin 2; Human Neutrophil Peptide 2; Neutrophil Defensin 2. Grade: ≥95%. Molecular formula: C147H217N43O37S6·xCF3COOH. Mole weight: 3370.96. | |
| Defensin HNP-3 (human) trifluoroacetate salt | Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It binds to recombinant, immobilized human surfactant protein D (SP-D; Kd = 55.7 nM) and inhibits focus formation in Madin-Darby canine kidney (MDCK) cells infected with influenza A virus (IAV). Synonyms: DEFA3 Protein; α-Defensin 3; Human Neutrophil Peptide 3; Neutrophil Defensin. Grade: ≥95%. Molecular formula: C151H222N44O40S6·xCF3COOH. Mole weight: 3486.05. | |
| Deferasirox 2-Glucuronide | Deferasirox 2-Glucuronide is a metabolite of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 2-[1-(4-carboxyphenyl)-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-3-yl]phenyl β-D-Glucopyranosiduronic acid; β-D-Glucopyranosiduronic acid, 2-[1-(4-carboxyphenyl)-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-3-yl]phenyl; Benzoic acid, 4-[3-[2-(β-D-glucopyranuronosyloxy)phenyl]-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-. Grade: >98%. CAS No. 1233196-92-3. Molecular formula: C27H23N3O11. Mole weight: 565.48. | |
| Deferasirox Acyl beta-D-Glucuronide | Deferasirox Acyl beta-D-Glucuronide is a metabolite of Deferasirox. Synonyms: 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid β-D-Glucuronide; Deferasirox Glucuronide. Grade: > 95%. CAS No. 1233196-91-2. Molecular formula: C27H23N3O10. Mole weight: 549.49. | |
| Deferasirox Benzoxazin Impurity | Intermediate in the production of Deferasirox. Synonyms: 2-(2-Hydroxyphenyl)-4H-1,3-benzoxazin-4-on; 2-(2-Hydroxyphenyl)benz[e][1,3]oxazin-4-one. Grade: > 95%. CAS No. 1218-69-5. Molecular formula: C14H9NO3. Mole weight: 239.23. | |
| Deferasirox Diacyl Impurity | An impurity of Deferasirox. Synonyms: 2,2'-Dihydroxydibenzamide; Disalicylamide. Grade: > 95%. CAS No. 1972-71-0. Molecular formula: C14H11NO4. Mole weight: 257.25. | |
| Deferasirox Ethyl Ester | Deferasirox Ethyl Ester is a derivative of Deferasirox. Synonyms: 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-benzoic Acid Ethyl Ester. Grade: > 95%. CAS No. 201530-79-2. Molecular formula: C23H19N3O4. Mole weight: 401.43. | |
| Deferasirox Fe3(addition) chelate | Deferasirox Fe3+ chelate is a rationally-designed oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias. Synonyms: Exjade Fe3+ chelate. Grade: >98%. CAS No. 554435-83-5. Molecular formula: C21H12FeN3O4. Mole weight: 426.18. | |
| Deferasirox Ferrate(III) Tripotassium Complex Methanoate | Deferasirox Ferrate(III) Tripotassium Complex Methanoate Hydrate is a metal complex of Deferasirox, which is an orally active tridentate iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: (OC-6-22')-Bis[4-[3,5-bis[2-(hydroxy-kO)phenyl]-1H-1,2,4-triazol-1-yl-kN4]benzoato(3-)]ferrate(3-) Tripotassium Methanoate; Ferrate(3-), bis[4-[3,5-bis[2-(hydroxy-κO)phenyl]-1H-1,2,4-triazol-1-yl-κN4]benzoato(3-)]-, tripotassium, (OC-6-22')-. Grade: ≥95%. CAS No. 554445-58-8. Molecular formula: C42H24FeK3N6O8. Mole weight: 913.82. | |
| Deferasirox Impurity 10 | Deferasirox Impurity 10 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C14H12N2O4. Mole weight: 272.26. | |
| Deferasirox Impurity 12 | Deferasirox Impurity 12 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C21H15N3O4. Mole weight: 373.36. | |
| Deferasirox Impurity 15 | Deferasirox Impurity 15 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C21H15N3O5. Mole weight: 389.36. | |
| Deferasirox Impurity 16 | Deferasirox Impurity 16 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C21H15N3O5. Mole weight: 389.26. | |
| Deferasirox Impurity 17 | Deferasirox Impurity 17 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C28H16N2O6S. Mole weight: 508.50. | |
| Deferasirox Impurity 18 | Deferasirox Impurity E is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: Deferasirox Impurity E. CAS No. 1688656-83-8. Molecular formula: C42H28N6O8S. Mole weight: 776.77. | |
| Deferasirox Impurity 19 (Mixture of Isomers) | Deferasirox Impurity 19 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C42H28N6O9S. Mole weight: 792.77. | |
| Deferasirox Impurity 20 | Deferasirox Impurity 20 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C42H28N6O9S. Mole weight: 792.77. | |
| Deferasirox Impurity 3 | Deferasirox Impurity. Synonyms: 13,14-(1,3-Butadiene-1,4-diyl)-[9,10-(1,3-butadiene-1,4-diyl)-[5,6-(1,3-butadiene-1,4-diyl)-[1,2-(1,3-butadiene-1,4-diyl)-4,8,12,16-tetraoxacyclohexadecane-1,5,9,13-tetraene-3,7,11,15-tetraone]]]. Grade: > 95%. CAS No. 6543-57-3. Molecular formula: C28H16O8. Mole weight: 480.43. | |
| Deferasirox Impurity 4 | Deferasirox Impurity 4 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C14H11NO4. Mole weight: 257.24. | |
| Deferasirox Impurity 5 | Deferasirox Impurity 5 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C21H15NO5. Mole weight: 361.35. | |
| Deferasirox Impurity 6 | Deferasirox Impurity 6 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C16H15NO4. Mole weight: 285.29. | |
| Deferasirox Impurity 7 | Deferasirox Impurity 7 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C16H15NO4. Mole weight: 285.29. | |
| Deferasirox Impurity 9 | Deferasirox Impurity 9 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 3-(3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)benzoic acid; Deferasirox 1,3-isomer; Benoic Acid. Molecular formula: C21H15N3O4. Mole weight: 373.36. | |
| Deferasirox Impurity D | Deferasirox Impurity D is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 3-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid; Deferasirox Impurity 9. Grade: >98%. Molecular formula: C21H15N3O4. Mole weight: 373.36. | |
| Deferasirox Impurity F | Deferasirox Impurity F is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: Deferasirox sulfoxide dimer. CAS No. 1688656-84-9. Molecular formula: C42H28N6O9S. Mole weight: 792.77. | |
| Deferasirox impurity G | Deferasirox Impurity G is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 6H-tribenzo[b,f,j][1,5,9]trioxacyclododecine-6,12,18-triimine. Molecular formula: C21H15N3O3. Mole weight: 357.36. | |
| Deferasirox Meta Isomer | Deferasirox Meta Isomer is an impurity compound of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 3-(3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)benzoic Acid; 3-(3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl). CAS No. 2254105-61-6. Molecular formula: C21H15N3O4. Mole weight: 373.36. | |
| Deferasirox Methyl Ester | Deferasirox Methyl Ester is a derivative of Deferasirox. Synonyms: 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-benzoic Acid Methyl Ester. Grade: > 95%. CAS No. 1266741-05-2. Molecular formula: C22H18N3O4. Mole weight: 387.39. | |
| Deferasirox Salicyloyl Ester | Deferasirox Saalicyloyl Ester is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 2-Hydroxybenzoic Acid 2-[1-(4-Carboxyphenyl)-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-3-yl]phenyl Ester. CAS No. 1395346-28-7. Molecular formula: C28H19N3O6. Mole weight: 493.47. | |
| Deferiprone | A chelator that could replace disferrioxamine. It is orally and parenterally effective in the removal of iron in vivo from rabbits and mice and also from transferrin and ferritin in vitro. Synonyms: 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone; 1,2-Dimethyl-3-hydroxy-4-pyridone; CP 20. Grade: 99 %. CAS No. 30652-11-0. Molecular formula: C7H9NO2. Mole weight: 139.15. | |
| Deferiprone 3-O-b-D-glucuronide | Deferiprone 3-O-b-D-glucuronide is a biomedicine used in the treatment of iron overload disorders, such as thalassemia and sickle cell anemia. It acts as an iron chelator helping to remove excess iron from the body. Its effectiveness in reducing iron levels has been studied extensively and it holds promise in improving overall patient health. Synonyms: 1,4-Dihydro-1,2-dimethyl-4-oxo-3-pyridinyl β-D-glucopyranosiduronic acid; CP 20 3-glucuronide; CP 20 3-O-glucuronide. CAS No. 141675-48-1. Molecular formula: C13H17NO8. Mole weight: 315.28. | |
| Deferoxamine | Deferoxamine, also known as desferrioxamine or DFO, is a medication used primarily for the treatment of iron overload in conditions such as thalassemia major and transfusional hemosiderosis. Deferoxamine is an iron-chelating agent, meaning it binds to excess iron in the body and forms a stable complex that is then excreted primarily through urine and feces. It binds to both ferric (Fe3+) and ferrous (Fe2+) ions, but its affinity for ferric iron is stronger. Deferoxamine can up-regulate HIF-1α level and induce apoptosis of cells. Deferoxamine is primarily used for the treatment of chronic iron overload due to repeated blood transfusions, such as in thalassemia major or sickle cell disease. It can also be used in cases of acute iron poisoning to help remove excess iron from the body. Synonyms: N-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxybutanediamide; 30-Amino-3,14,25-trihydroxy-3,9,14,20,25-pentaazatriacontane-2,10,13,21,24-pentaone; Deferoxamin; Deferoxamine B; Deferriferrioxamine B; Deferrioxamine; Deferrioxamine B; Desferan; Desferex; Desferin; Desferioxamine B; Desferoxime; Desferrin; Desferrioxamine; Desferrioxamine. Grade: ≥95%. CAS No. 70-51-9. Molecular formula: C25H48N6O8. Mole weight: 560.69. | |
| Deflazacort Impurity C | An impurity of Deflazacort, which is a systemic corticosteroid, used for rheumatoid arthritis and lupus. Grade: > 95%. CAS No. 710951-92-1. Molecular formula: C27H33NO7. Mole weight: 483.55. | |
| Defluoro Aprepitant | A metabolite of Aprepitant, a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. Synonyms: Desfluoro aprepitant; Aprepitant Impurity A; 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]-ethoxy]-3-phenylmorpholin-4-yl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Aprepitant EP Impurity A; 5-([(2R,3S)-2-((R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy)-3-phenylmorpholino]methyl)-1H-1,2,4-triazol-3(2H)-one; Aprepitant desfluoro; 5-[[(2R,3S)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-phenylmorpholino]methyl]-2H-1,2,4-triazol-3(4H)-one. Grade: >95%. CAS No. 170729-76-7. Molecular formula: C23H22F6N4O3. Mole weight: 516.45. | |
| Defluoro Fosaprepitant Dimeglumine | Defluoro Fosaprepitant Dimeglumine is an extraordinary pharmaceutical compound, finding extensive application in the biomedical research with the potent blockade of central nervous system-associated substance P/neurokinin 1 receptors. Grade: > 95%. Molecular formula: C37H57F6N6O16P. Mole weight: 986.87. | |
| Defluoro Levofloxacin | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: (3S)-2,3-Dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid; Levofloxacin Related Compound F (USP). Grade: > 95%. CAS No. 117620-85-6. Molecular formula: C18H21N3O4. Mole weight: 343.39. | |
| Defluoro Linezolid | Defluoro Linezolid is an impurity of Linezolid, which is an antibiotic used for the treatment of infections caused by Gram-positive bacteria. Synonyms: (S)-N-{[3-(4-Morpholinophenyl)-2-oxooxazolidin-5-yl]methyl}acetamide; Desfluoro linezolid; N-[[(5S)-3-[4-(4-Morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; Acetamide, N-[[(5S)-3-[4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-; Desfluorolinezolid; 1-({[(5S)-3-(p-Morpholinophenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}amino)-1-ethanone. Grade: ≥95%. CAS No. 556801-15-1. Molecular formula: C16H21N3O4. Mole weight: 319.36. | |
| Defluoroofloxacin | An impurity of Ofloxacin, which is a synthetic broad-spectrum antimicrobial agent. Synonyms: Defluoroofloxacin, (+/-)-. CAS No. 95848-94-5. Molecular formula: C18H21N3O4. Mole weight: 343.4. | |
| Defluoro Prasugrel Hydrochloride | Defluoro Prasugrel Hydrochloride is an impurity of Prasugrel, which is a platelet inhibitor used to prevent formation of blood clots. Synonyms: Prasugrel Desfluoro Hydrochloride. CAS No. 1391053-53-4. Molecular formula: C20H22ClNO3S. Mole weight: 391.9. | |
| Degrasyn | Degrasyn, also known as WP1130, is a small molecule that specifically and rapidly down-regulates both wild-type and mutant Bcr/Abl protein without affecting bcr/abl gene expression in chronic myelogenous leukemia (CML) cells and Hsp90/Hsp70 ratios within the cells. WP1130 was more effective in reducing leukemic versus normal hematopoietic colony formation and strongly inhibited colony formation of cells derived from patients with T315I mutant Bcr/Abl-expressing CML in blast crisis. WP1130 suppressed the growth of K562 heterotransplanted tumors as well as both wild-type Bcr/Abl and T315I mutant Bcr/Abl-expressing BaF/3 cells transplanted into nude mice. WP1130 may be useful in treating CML. MM1: IC50 = 1 μM (human); U-266: IC50 = 1.3 μM (human); USP9X: IC50 = 3 μM (human); UCH-L1: IC50 = 3 μM (human); USP5: IC50 = 3 μM (human) In vitro: a partly selective DUB inhibitor, directly inhibiting DUB activity of USP9x, USP5, USP14, and UCH37, which are known to regulate survival protein stability and 26S proteasome function; In vivo: suppressed the growth of K562 heterotransplanted tumors as well as both wild-type Bcr/Abl and T315I mutant Bcr/Abl-expressing BaF/3 cells transplanted into nude mice. Uses: Downregulate the antiapoptotic proteins bcr/abl and jak2 and to upregulate the proapoptotic proteins mcl-1 and p53; selective small molecular deubiquitinase (usp5, uch-l1, usp9x, usp14, and uch37) inhibitor mm1: ic50 = 1 & | |
| Dehydroaltenusin | Dehydroaltenusin is a selective eukaryotic DNA polymerase α inhibitor and a type of antibiotic produced by a fungus (IC50 = 0.68 μM). Dehydroaltenusin inhibits mammalian pol α activity. Dehydroaltenusin arrests the cancer cell cycle at the S-phase and triggers apoptosis. Dehydroaltenusin possesses anti-tumor activity against human adenocarcinoma tumor in vivo. Uses: Enzyme inhibitors. Synonyms: 6H-Dibenzo(b,d)pyran-2,6(4ah)-dione, 3,7-dihydroxy-9-methoxy-4a-methyl-, (4aS)-; (S)-Dehydroaltenusin. CAS No. 31186-13-7. Molecular formula: C15H12O6. Mole weight: 288.25. | |
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