BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| D-Cellotriose | D-Cellotriose is an intriguing compound, effectively curbing the proliferation of malignant cells by perturbing their intricate metabolic cascades. Synonyms: Cellotriose; 1,4-b-D-Cellotriose; O-β-D-Glucopyranosyl-(1->4)-O-β-D-glucopyranosyl-(1->4)-D-glucose; (Glc1-b-4)2-D-Glc; D-(+)-Cellotriose; beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->4)-D-glucose; beta-D-Glcp-(1->4)-beta-D-Glcp-(1->4)-D-Glc. Grade: ≥95%. CAS No. 33404-34-1. Molecular formula: C18H32O16. Mole weight: 504.44. |  |
| D-Cellotriose undecaacetate | D-Cellotriose undecaacetate is a groundbreaking biomedical entity, facilitating the research of afflictions such as cancer, diabetes and cardiovascular maladies. Remarkably, the encasement and safeguarding of said compounds by D-Cellotriose undecaacetate culminate in heightened fortitude and bio-dissolvability. Synonyms: D-Glucopyranose, O-2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl-(1→4)-O-2,3,6-tri-O-acetyl-β-D-glucopyranosyl-(1→4)-, tetraacetate; Cellotriose, undecaacetate; D-Cellotriose hendecaacetate; Cellotriose hendecaacetate; O-2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl-(1→4)-O-2,3,6-tri-O-acetyl-β-D-glucopyranosyl-(1→4)-D-glucopyranose, tetraacetate; D-(+)-Cellohexose Eicosaacetate. CAS No. 17690-94-7. Molecular formula: C40H54O27. Mole weight: 966.84. | |
| DCG IV | DCG IV is a potent group II mGluR agonist and a presynaptic depressant. Uses: Anticonvulsants. Synonyms: (2S,2'R,3'R)-2-(2',3'-Dicarboxycyclopropyl)glycine; (1R,2R)-3-[(S)-amino(carboxy)methyl]cyclopropane-1,2-dicarboxylic acid. Grade: ≥98% by HPLC. CAS No. 147782-19-2. Molecular formula: C7H9NO6. Mole weight: 203.15. | |
| d[Cha4]-AVP | d[Cha4]-AVP is a selective and potent human vasopressin V1B receptor agonist with Ki value of 1.2 nM. It stimulates corticosterone and ACTH secretion. It shows negligible vasopressor activity in vivo. Synonyms: 3-Mercaptopropionyl-Tyr-Phe-b-cyclohexyl-Ala-Asn-Cys-Pro-Arg-Gly-NH2; (Deamino-Cys¹,β-cyclohexyl-Ala?,Arg?)-Vasopressin. CAS No. 500170-27-4. Molecular formula: C50H71N13O11S2. Mole weight: 1094.31. | |
| d[Cha4]-AVP acetate | d[Cha4]-AVP is a selective and potent human vasopressin V1B receptor agonist with Ki value of 1.2 nM. It stimulates corticosterone and ACTH secretion. It shows negligible vasopressor activity in vivo. Molecular formula: C52H75N13O13S2. Mole weight: 1154.4. | |
| dC-H-Phosphonate, DBU Salt | dC-H-Phosphonate, DBU Salt is an immensely robust biochemical compound with paramount significance lying in the synthesis of phosphonate-modified DNA. It assumes the role of a nucleotide analog during DNA replication. Synonyms: 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyCytidine, 3'-H-phosphonate, DBU salt. Molecular formula: C46H52N5O9P. Mole weight: 849.35. | |
| D-Cl-amidine | Cl-Amidine is an irreversible inhibitor of protein arginine deiminases (PADs; IC50s = 0.8, 6.2, and 5.9 μM for PAD1, PAD3, and PAD4, respectively). It is cytotoxic to HL-60, MCF-7, and HT-29 cancer cells (IC50s = 0.25, 0.05, and 1 μM, respectively). Synonyms: (R)-N-(1-Amino-5-(2-chloroacetimidamido)-1-oxopentan-2-yl)benzamide. CAS No. 1404060-15-6. Molecular formula: C14H19ClN4O2. Mole weight: 310.78. | |
| D-Cl-amidine hydrochloride | Cl-Amidine is an irreversible inhibitor of protein arginine deiminases (PADs; IC50s = 0.8, 6.2, and 5.9 μM for PAD1, PAD3, and PAD4, respectively). It is cytotoxic to HL-60, MCF-7, and HT-29 cancer cells (IC50s = 0.25, 0.05, and 1 μM, respectively). Grade: ≥98%. Molecular formula: C14H20Cl2N4O2. Mole weight: 347.24. | |
| DCLK1-IN-1 | DCLK1-IN-1 is a selective DCLK1 inhibitor and a powerful tool to dissect DCLK1 biological functions. DCLK1-IN-1 binds DCLK1 long isoforms but does not prevent DCLK1's Microtubule-Associated Protein (MAP) function. Synonyms: 2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-11-methyl-5-(2,2,2-trifluoroethyl)-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one. CAS No. 2222635-15-4. Molecular formula: C26H28F3N7O2. Mole weight: 527.54. | |
| dCMPαS | dCMPαS, an analogue of deoxycytidine monophosphate, has demonstrated significant antiviral activity against a diverse array of viruses. When utilized to manage viral infections, such as herpes simplex virus, cytomegalovirus and the Epstein-Barr virus, dCMPαS operates by obstructing the viral DNA synthesis. Its modus operandi involves competitive inhibition of the viral DNA polymerase. Synonyms: 2'-Deoxycytidine-5'-(α-thio)-monophosphate, Sodium salt; 2'-Deoxycytidine-5'-O-monophosphorothioate. Grade: ≥ 97% by HPLC. CAS No. 63225-09-2. Molecular formula: C9H14N3O6PS (free acid). Mole weight: 323.26 (free acid). | |
| d(CpA) | d(CpA) is a synthetic deoxyribonucleotide comprising cytosine and adenine bases linked by a phosphodiester bond. It serves as a valuable tool in compound for studying DNA-protein interactions and genetic regulation. Additionally, d(CpA) can be used for designing DNA-based drugs to study specific diseases such as cancer and viral infections. Synonyms: dCpdA DNA Dinucleotide (5'-3'). Grade: ≥95% by AX-HPLC. Molecular formula: C19H25N8O9P. Mole weight: 540.40. | |
| dCpCpp | dCpCpp serves as a pivotal chemical compound, intricately involved in the synthesis of modified nucleotides. Specifically, in the realm of RNA research, dCpCpp plays a crucial role in constructing modified RNA molecules, thereby facilitating the deciphering of intricate RNA-protein interactions. Moreover, dCpCpp imparts its catalytic prowess as a substrate for RNA polymerase, enabling the efficient enzymatic synthesis of modified RNA strands. Synonyms: (dCMPCPP); 2'-Deoxycytidine-5'-[(α,β)-methyleno]triphosphate, Sodium salt; dCpCpp (dCMPCPP). Grade: ≥ 95% by HPLC. CAS No. 941569-33-1. Molecular formula: C10H18N3O12P3 (free acid). Mole weight: 465.18 (free acid). | |
| dCpdC | dCpdC, a nucleoside analog drug revered for its ability to combat DNA viruses (such as herpes simplex and varicella-zoster) by interrupting viral DNA replication and preventing further spread, so promisingly shines as an option for treating various forms of cancer - an astonishing feat given its molecular foundation. Synonyms: dCpdC DNA Dinucleotide (5'-3'). Grade: ≥95% by AX-HPLC. Molecular formula: C18H25N6O10P. Mole weight: 516.40. | |
| DCPG | DCPG is a potent and selective mGlu8a agonist (EC50 = 31 nM) displaying > 100-fold selectivity over mGlu1-7. It increases c-Fos expression in stress-related brain areas following systemic administration in mice in vivo. Synonyms: (S)-3,4-DCPG; (S)-3,4-Dicarboxyphenylglycine; 4-[Amino(carboxy)methyl]phthalic acid. Grade: ≥98% by HPLC. CAS No. 201730-11-2. Molecular formula: C10H9NO6. Mole weight: 239.18. | |
| DCPIB | DCPIB is a potent and selective volume-sensitive anion channel (VSAC) blocker, swell in various cardiovascular tissues (IC50 = 4.1 μM in CPAE cells). It inhibits glucose-stimulated insulin in intact β-cells, and reverses cell swelling-induced action potential duration shortening in atrial myocytes and inhibits astroglial swelling in vitro. Synonyms: 4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]butanoic acid. Grade: ≥98% by HPLC. CAS No. 82749-70-0. Molecular formula: C22H28Cl2O4. Mole weight: 427.37. | |
| DCPLA-ME | DCPLA-ME is a potent PKCε activator for use in the treatment of neurodegenerative diseases. Synonyms: 2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester; DCPLA methyl ester. Grade: ≥98%. CAS No. 56687-67-3. Molecular formula: C21H38O2. Mole weight: 322.53. | |
| dCpNHpp | dCpNHpp is a nucleotide analog, dedicated to unraveling the intricate intricacies of DNA replication and repair mechanisms. It effectively curtails the activity of specific enzymes implicated in DNA synthesis. Synonyms: (dCMPNPP); 2'-Deoxycytidine-5'-[(α,β)-imido]triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 791761-70-1. Molecular formula: C9H17N4O12P3 (free acid). Mole weight: 466.17 (free acid). | |
| D-CPP-ene | D-CPP-ene has been found to be an effective and competitive NMDA antagonist. Synonyms: D-CPP-ene; SDZ-EAA 494; SDZ-EAA-494; SDZ-EAA494; Midafotel; D-4-[(2E)-3-Phosphono-2-propenyl]-2-piperazinecarboxylic acid. Grade: ≥95% by HPLC. CAS No. 117414-74-1. Molecular formula: C8H15N2O5P. Mole weight: 250.19. | |
| DC-Srci-6649 | DC-Srci-6649 is a c-Src kinase inhibitor that inhibits the phosphorylation and locks c-Src in the inactive state. Synonyms: DC Srci 6649. Grade: 98%. CAS No. 1037545-61-1. Molecular formula: C20H22Cl2N2O2S. Mole weight: 425.37. | |
| dC-Thiophosphoramidite | dC-Thiophosphoramidite is a reagent used in the synthesis of oligonucleotides for research purposes. It is a modified form of the nucleoside cytidine and contains a thiophosphate group, which allows for the creation of phosphorothioate linkages. These modified oligonucleotides have been shown to have increased stability and efficacy for use in gene therapy and antisense technology targeting diseases such as cancer and viral infections. Synonyms: 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyCytidine, 3'-[(ß-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite. Molecular formula: C50H51N4O8PS2. Mole weight: 931.07. | |
| dCTPαS | DCTPαS, a nucleotide analogue that has gained widespread attention in biomedical research, serves as a critical tool in DNA replication and repair studies, as well as RNA transcript labeling and protein-DNA interaction detection. Even more impressively, preliminary investigations suggest the potential therapeutic significance of dCTPαS, presenting exciting possibilities for its application in cancer and viral infection treatment. Synonyms: 2'-Deoxycytidine-5'-(α-thio)-triphosphate, Sodium salt (1 : 1 Mixture of Rp and Sp isomers). Grade: ≥ 95% by HPLC. CAS No. 64145-29-5. Molecular formula: C9H16N3O12P3S (free acid). Mole weight: 483.22 (free acid). | |
| dCTP - lyophilized | The lyophilized form of dCTP. dCTP is a nucleoside triphosphate used in DNA synthesis by being incorporated into DNA strand. Synonyms: 2'-Deoxycytidine-5'-triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C9H13N3Na3O13P3* 3H2O. Mole weight: 587.14. | |
| dCTP solution - Lithium Salt | The lithium salt solution form of dCTP. dCTP is a nucleoside triphosphate used in DNA synthesis by being incorporated into DNA strand. Grade: ≥ 99% by HPLC. Molecular formula: C9H16N3O13P3 (free acid). Mole weight: 467.15 (free acid). | |
| dCTP solution - Sodium Salt | The sodium salt solution form of dCTP. dCTP is a nucleoside triphosphate used in DNA synthesis by being incorporated into DNA strand. Grade: ≥ 99% by HPLC. Molecular formula: C9H16N3O13P3 (free acid). Mole weight: 467.15 (free acid). | |
| DCU | Dicloralurea, a veterinary food additive, could restrain the formation of methane in herbicide ruminants for behaving as a growth stimulant. Uses: Dicloralurea is commonly used as a veterinary food additive for it could restrain the formation of methane in herbicide ruminants for behaving as a growth stimulant. Synonyms: 1,3-bis(1-hydroxy-2,2,2-trichloroethyl)urea; 1,3-bis(1-hydroxy-2,2,2-trichloroethyl)urea[qr]; 1,3-bis(2,2,2-trichloro-1-hydroxyethyl)-ure; 1,3-bis(2,2,2-trichloro-1-hydroxyethyl)urea; 1,3-bis(2,2,2-trichloro-1-hydroxyethyl)urea[qr]; cragdcu-73w. Grade: 95%. CAS No. 116-52-9. Molecular formula: C5H6Cl6N2O3. Mole weight: 354.83. | |
| DCVC | DCVC is one of cysteine impurities. It has potential anticancer activity against tumor cell growth. DCVC has been found to influence sort of cytokines release stimulated by pathogen. Uses: Dcvc has been found to influence sort of cytokines release stimulated by pathogen. Synonyms: S-(trans-1,2-Dichlorovinyl)-L-cysteine; (E)-S-(1,2-Dichloroethenyl)-L-cysteine; L-Cysteine, S-((1E)-1,2-dichloroethenyl)-; ALANINE, 3-((1,2-DICHLOROVINYL)THIO)-, (E)-L-; AC1O5GGP. Grade: 98%. CAS No. 13419-46-0. Molecular formula: C5H7Cl2NO2S. Mole weight: 216.09. | |
| D-Cyclohexylalanine-D-glutamate-glycine-13C2-15N TFA Salt | D-Cyclohexylalanine-D-glutamate-glycine-13C2-15N TFA Salt. Grade: 95% by HPLC; 98% atom 13C, 98% atom 15N. Molecular formula: [13C]2C16H29[15N]N2O8F3. Mole weight: 475.41. | |
| D-Cycloserine dimer | D-Cycloserine dimer is an intermediate in the biosynthesis of S-adenosylmethionine, a cofactor for enzyme-catalyzed methylations. Synonyms: (3R,6R)-3,6-Bis[(aminooxy)methyl]-2,5-piperazinedione; D-3,6-Bis(aminooxymethyl)-2,5-diketopiperazine; D-3,6-Bis(aminoxymethyl)-2,5-dioxopiperazine. Grade: > 95%. CAS No. 16337-02-3. Molecular formula: C6H12N4O4. Mole weight: 204.18. | |
| D-Cys(1)-AVP | D-Cys(1)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Cys(1)-Vasopressin; Vasopressin, 1-D-cysteine-8-L-arginine-; H-D-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); D-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 66513-07-3. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24. | |
| D-Cys(2)-Octreotide | D-Cys(2)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: DPhe-DCys-Phe-DTrp-Lys-Thr-Cys-Thr-ol(Cys2&Cys7 bridge); [2-D-Cysteine]octreotide; DPhe-DCys-F-DTrp-KTC-Thr-ol(Cys2&Cys7 bridge); Octreotide EP Impurity G; D-Phenylalanyl-D-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); Octreotide Impurity-6; H-D-Phe-D-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); D-Phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2→7)-disulfide; L-Cysteinamide, D-phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-; L-Cysteinamide, D-phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide. Grade: ≥95%. CAS No. 108102-47-2. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25. | |
| D-Cys(2)-Octreotide trifluoroacetate salt | D-Cys(2)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: H-D-Phe-D-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol trifluoroacetate salt (Disulfide bridge: Cys2-Cys7); Octreotide EP Impurity G trifluoroacetate salt. Grade: 95%. | |
| D-Cys(4)-Terlipressin Trifluoroacetic Acid Salt | D-Cys(4)-Terlipressin Trifluoroacetic Acid Salt is an impurity of Terlipressin, which is a partial agonist of the vasopressin V1A receptor used as a vasoactive drug in the management of low blood pressure. Synonyms: (2S)-1-[(4R,7S,10S,13S,16S,19S)-19-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Trifluoroacetic Acid Salt; H-Gly-Gly-Gly-D-Cys(1)-Tyr-Phe-Gln-Asn-Cys(1)-Pro-Lys-Gly-NH2.TFA; glycyl-glycyl-glycyl-D-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (4->9)-disulfide TFA. Grade: >98%. Molecular formula: C52H74N16O15S2.xC2HF3O2. Mole weight: 1227.37 (free base). | |
| D-Cys(6)-AVP | D-Cys(6)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Cys(6)-Vasopressin; Vasopressin, 6-D-cysteine-8-L-arginine-; H-Cys-Tyr-Phe-Gln-Asn-D-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-D-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 163659-75-4. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24. | |
| D-Cys7-Eptifibatide | An impurity of Eptifibatide. Eptifibatide is a glycoprotein IIb/IIIa inhibitor used primarily to prevent blood clots in patients with acute coronary syndromes (ACS) and during percutaneous coronary interventions (PCI). Synonyms: Mpr-Har-Gly-Asp-Trp-Pro-DCys-NH2(Mpr1&Cys7 bridge); Mpr-Har-GDWP-DCys-NH2(Mpr&Cys bridge); deamino-Cys-hArg-Gly-Asp-Trp-Pro-D-Cys-NH2 (Disulfide bridge: Cys1-Cys7); Deamino-cysteinyl-L-homoarginyl-glycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-D-cysteinamide (1->7)-disulfide; D-Cys7 Eptifibatide; 7-D-Cys Eptifibatide; [D-Cys]7-Eptifibatide; [D-Cys7]-Eptifibatide; D-Cys(7)-Eptifibatide; (D-Cys)7 Eptifibatide impurity. Grade: ≥95%. Molecular formula: C35H49N11O9S2. Mole weight: 831.97. | |
| D-Cys(7)-Octreotide | D-Cys(7)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: DPhe-Cys-Phe-DTrp-Lys-Thr-DCys-Thr-ol(Cys2&Cys7 bridge); [7-D-cysteine]octreotide; Octreotide EP Impurity B; [D-Cys7]-Octreotide; D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-D-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-D-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); D-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; DPhe-CF-DTrp-KT-DCys-Thr-ol(Cys2&Cys7 bridge). Grade: 98%. CAS No. 1211530-36-7. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25. | |
| DCZ0415 | DCZ0415 is a TRIP13 inhibitor that impairs nonhomologous end joining repair and inhibits NF-κB activity. DCZ0415 clinically for the treatment of a subset of CRCs that exhibit dysregulated TRIP13 and FGFR4. Synonyms: 2-(4-(Pyridin-4-ylmethyl)phenyl)-4,4a,5,5a,6,6a-hexahydro-4,6-ethenocyclopropa[f]isoindole-1,3(2H,3aH)-dione. Grade: 99%. CAS No. 2242470-43-3. Molecular formula: C23H20N2O2. Mole weight: 356.42. | |
| DD1 | DD1 is a proteasome inhibitor that targets Bax activation and P70S6K degradation during acute myeloid leukemia (AML) apoptosis. Synonyms: 3,3'-Diamino-4'-methoxyflavone; 4H-1-Benzopyran-4-one, 3-amino-2-(3-amino-4-methoxyphenyl)-. Grade: >98%. CAS No. 187585-11-1. Molecular formula: C16H14N2O3. Mole weight: 282.29. | |
| D-(+)-Darunavir | D-(+)-Darunavir is a highly efficacious antiretroviral compound, demonstrating compelling utility in studying HIV-1 infection. By impeding the viral protease enzyme, its pharmacological action effectively averts the fragmentation of viral polyproteins, thereby decisively impeding viral replication. Synonyms: (+)-Darunavir; 1399859-60-9; D-(+)-Darunavir; Darunavir, (+)-; NCL9DHY4E3; UNII-NCL9DHY4E3; (3S,3aR,6aS)-Hexahydrofuro(2,3-b)furan-3-yl ((2R,3S)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate; [(3aR,4S,6aS)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2R,3S)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate; Carbamic acid, N-((1R,2S)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-, (3S,3aR,6aS)-hexahydrofuro(2,3-b)furan-3-yl ester; (3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl ((2R,3S)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate. Grade: > 95%. CAS No. 1399859-60-9. Molecular formula: C27H37N3O7S. Mole weight: 547.66. | |
| ddATP-α-S | ddATP-α-S is used in mass spectrometric genotyping. Synonyms: 2', 3'- Dideoxyadenosine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers. Grade: ≥ 95% by HPLC for mixture of Rp-/Sp-isomers. CAS No. 154902-26-8. Molecular formula: C10H16N5O10P3S (free acid). Mole weight: 491.3 (free acid). | |
| ddCTP | ddCTP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddCTP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dCTP in cells. Uses: Ddctp is an inhibitor of reverse transcriptases from retroviruses. Synonyms: 2',3'-Dideoxycytidine-5'-Triphosphate; Zalcitabine triphosphate; Cytidine 5'-(tetrahydrogen triphosphate), 2',3'-dideoxy-. Grade: ≥95% by AX-HPLC. CAS No. 66004-77-1. Molecular formula: C9H16N3O12P3 (free acid). Mole weight: 451.16 (free acid). | |
| ddCTP-α-S | ddCTP-α-S is used in mass spectrometry genotyping. Synonyms: 2', 3'- Dideoxycytidine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers. Grade: ≥ 95% by HPLC for mixture of Rp-/Sp-isomers. CAS No. 154771-49-0. Molecular formula: C9H16N3O11P3S (free acid). Mole weight: 467.2 (free acid). | |
| DDD107498 | DDD107498 is a novel multiple-stage antimalarial agent that inhibits P. falciparum translation elongation factor 2. Synonyms: M-5717; DDD-498; DDD498; DDD-107498. CAS No. 1469439-69-7. Molecular formula: C27H31FN4O2. Mole weight: 462.56. | |
| DDD107498 succinate | DDD107498 succinate is a potent and orally active antimalarial inhibitor. It inhibits multiple life-cycle stages of the parasite, with an EC50 of 1 nM against P. falciparum 3D7. Synonyms: DDD-498 succinate. Grade: 99%. CAS No. 2444781-71-7. Molecular formula: C31H37FN4O6. Mole weight: 580.65. | |
| DDD-85365 | DDD-85365 is an oral drug developed promisingly for the treatment of visceral leishmaniasis. Uses: The potential treatment of visceral leishmaniasis. Synonyms: DDD 85365; DDD85365. | |
| DDD85646 | DDD85646 is a moderately bioavailable pyrazole sulphonamide inhibitor of T. brucei N-myristoyltransferase (TbNMT) with an apparent Ki value of 1.44 nM. Synonyms: IMP-366; 2,6-Dichloro-4-(2-Piperazin-1-Ylpyridin-4-Yl)-N-(1,3,5-Trimethyl-1h-Pyrazol-4-Yl)benzenesulfonamide. Grade: ≥98%. CAS No. 1215010-55-1. Molecular formula: C21H24Cl2N6O2S. Mole weight: 495.4. | |
| D-Decamannuronic acid decasodium salt | D-decamannuronic acid decasodium salt is an invaluable biomedical breakthrough facilitating targeted researchs for diverse diseases, encompassing inflammatory conditions, bacterial infections and immune disorders. Grade: ≥93% by GPC. Molecular formula: C60H72O61Na10. Mole weight: 1999.07. | |
| D-Desosamine | D-Desosamine is a sugar of innate origins bravely hindering bacterial proliferation, particularly augmenting erythromycin's power. Synonyms: D-xylo-Hexose, 3,4,6-trideoxy-3-(dimethylamino)-; 3,4,6-trideoxy-3-dimethylamino-D-xylo-hexose; 3-Dimethylamino-3,4,6-trideoxy-D-xylo-hexose. Grade: ≥95%. CAS No. 5779-39-5. Molecular formula: C8H17NO3. Mole weight: 175.23. | |
| ddGTP | ddGTP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddGTP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dGTP in cells. Uses: Ddgtp is an inhibitor of reverse transcriptases from retroviruses. Synonyms: 2',3'-Dideoxyguanosine-5'-Triphosphate. Grade: ≥95% by AX-HPLC. CAS No. 68726-28-3. Molecular formula: C10H16N5O12P3 (free acid). Mole weight: 491.18 (free acid). | |
| ddGTP-α-S | ddGTP-α-S is used in mass spectrometric genotyping. Synonyms: 2', 3'- Dideoxyguanosine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers. Grade: ≥ 95% by HPLC for mixture of Rp-/Sp-isomers. CAS No. 154771-50-3. Molecular formula: C10H16N5O11P3S (free acid). Mole weight: 507.3 (free acid). | |
| D-Digitalose | D-Digitalose is an advanced pharmacological compound, exhibiting utmost proficiency in studying the complexities of heart failure and irregular cardiac rhythms. This compound is classified under the realm of cardiac glycosides. Synonyms: 6-Deoxy-3-O-methyl-D-galactose. CAS No. 4481-8-7. Molecular formula: C7H14O5. Mole weight: 178.18. | |
| D-Digitoxose Tribenzoate | D-Digitoxose derivative. A derivative of D-ribo-Hexonic acid that liver metabolized. It is a glucose-stimulated insulin release inhibitor. Synonyms: 2,6-Dideoxy-β-D-ribo-hexopyranose Tribenzoate. CAS No. 104652-04-2. Molecular formula: C27H24O7. Mole weight: 460.48. | |
| DDMS | DDMS is a mechanism-based irreversible inhibitor with a 10-fold selectivity for CYP4A2 enzymes, which are mainly synthesized into 20-hete in mammalian kidneys. Synonyms: Dibromo-dodecenyl-methylsulfimide; 12,12-Dibromo-N-(methylsulfonyl)-11-dodecenamide. Grade: ≥98%. CAS No. 206052-03-1. Molecular formula: C13H23Br2NO3S. Mole weight: 433.2. | |
| ddNTP bundle | ddNTP bundle is a mixture of ddATP, ddTTP, ddGTP and ddCTP. ddNTP is an inhibitor of DNA polymerase used to terminate chain extension. Uses: Ddntp is an inhibitor of dna polymerase. Synonyms: 2',3'-Dideoxyadenosine-5'-triphosphate, Lithium salt; 2',3'-Dideoxycytidine-5'-triphosphate, Lithium salt; 2',3'-Dideoxyguanosine-5'-triphosphate, Lithium salt; 2',3'-Dideoxythymidine-5'-triphosphate, Lithium salt. Grade: ≥ 98% by HPLC, functionally tested by chain termination sequencing reactions. Molecular formula: ddATP: C10H16N5O11P3 (free acid); ddCTP: C9H16N3O12P3 (free acid); ddGTP: C10H16N5O12P3 (free acid); ddTTP: C10H17N2O13P3 (free acid). Mole weight: ddATP: 475.18 (free acid); ddCTP: 451.16 (free acid); ddGTP: 491.18 (free acid); ddTTP: 466.17 (free acid). | |
| DDO-2093 | DDO-2093 is a potent inhibitor of MLL1-WDR5 protein-protein interaction with an IC50 of 8.6 nM and a Kd of 11.6 nM. It shows antitumor activity and selectively inhibits the catalytic activity of MLL complex. Synonyms: 1H-1,2,3-Triazole-4-carboxamide, 1-[3-[(5-amino-2-chloro-4-fluoro-3-methylbenzoyl)amino]-4-(4-methyl-1-piperazinyl)phenyl]-N-[3-(4-morpholinyl)propyl]-. CAS No. 2250024-74-7. Molecular formula: C29H37ClFN9O3. Mole weight: 614.11. | |
| DDO-5936 | DDO-5936 is a potent Hsp90-Cdc37 PPI inhibitor. DDO-5936 disrupts the Hsp90-Cdc37 interaction, represses cell proliferation through a strong correlation with the Hsp90-Cdc37 expression level, and selectively down-regulates kinase clients of Hsp90. Synonyms: DDO5936; DDO 5936; 2-(2,4,6-trimethyl-N-(4-((2-(pyrrolidin-1-yl)pyrimidin-4-yl)amino)phenyl)phenylsulfonamido)acetic acid. Grade: >98%. CAS No. 2355377-13-6. Molecular formula: C25H29N5O4S. Mole weight: 495.59. | |
| DDO-6600 | DDO-6600 is a heat shock protein (Hsp90) inhibitor. DDO-6600 is identified to covalent modification of Cys598 on Hsp90 from in silico study. Synonyms: (E)-1-(3-(3-(3,4-Dimethylphenyl)-1-phenyl-1H-pyrazol-4-yl)acryloyl)piperidine-2-carboxamide. Grade: 99%. CAS No. 2640292-37-9. Molecular formula: C26H28N4O2. Mole weight: 428.53. | |
| DDP-38003 trihydrochloride | DDP-38003 trihydrochloride is the trihydrochloride salt of DDP-38003 which is a potent, selective, oral bioavailable irreversible inhibitor of KDM1A. Synonyms: DDP-38003 trihydrochloride; DDP 38003 trihydrochloride; DDP38003 trihydrochloride; N-[4-[(1S,2R)-2-aminocyclopropyl]phenyl]-4-(4-methylpiperazin-1-yl)benzamide; trihydrochloride; DDP-38003 (trihydrochloride). Molecular formula: C21H29Cl3N4O. Mole weight: 459.84. | |
| DDR1-IN-1 | DDR1-IN-1 is a potent and selective discoidin domain receptor 1 (DDR1) receptor tyrosine kinase inhibitor with IC50 of 105 nM, about 3-fold selectivity over DDR2. Synonyms: DDR1-IN 1; DDR1-IN1; DDR1 IN 1. Grade: 98%. CAS No. 1449685-96-4. Molecular formula: C30H31F3N4O3. Mole weight: 552.59. | |
| DDR1-IN-1 dihydrochloride | DDR1-IN-1 dihydrochloride is a selective discoidin domain receptor 1 (DDR1) tyrosine kinase inhibitor (IC50 = 105 and 413 nM for DDR1 and DDR2, respectively). Synonyms: DDR1 IN 1 dihydrochloride; N-[3-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)oxy]-4-methylphenyl]-4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)benzamide dihydrochloride. Grade: ≥98% by HPLC. CAS No. 1780303-76-5. Molecular formula: C30H31F3N4O3.2HCl. Mole weight: 625.51. | |
| DDR1-IN-1 hydrate | DDR-IN-1 has been shown to inhibit colorectal cancer cell lines when used in combination with the PI3K/mTOR inhibitor. DDR1-IN-1 binds to DDR1 and inhibits DDR1 autophosphorylation with an IC50 value of 105 nM and an EC50 value of 87 nM. Synonyms: Discoidin Domain Receptor 1-IN-1. Grade: ≥95%. Molecular formula: C30H31F3N4O3·3/4H2O. Mole weight: 566.1. | |
| DDR1-IN-5 | DDR1-IN-5, a selective Discoidin domain receptor 1 (DDR1) inhibitor (IC50 = 7.36 nM), has anticancer activity. It inhibits the autophosphorylation of DDR1b (Y513) with an IC50 of 4.1 nM. Synonyms: 1,2-Benzisoxazol-3-amine, 7-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-6-methyl-N-[5-(trifluoromethyl)-3-pyridinyl]-. Grade: ≥95%. CAS No. 2416022-90-5. Molecular formula: C22H13F3N6O. Mole weight: 434.37. | |
| DDR1-IN-6 | DDR1-IN-6, a selective Discoidin domain receptor 1 (DDR1) inhibitor (IC50 = 9.72 nM), has anticancer activity. It inhibits the autophosphorylation of DDR1b (Y513) with an IC50 of 9.7 nM. Synonyms: 1,2-Benzisoxazol-3-amine, 7-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-6-methyl-N-[3-(trifluoromethyl)phenyl]-. CAS No. 2416021-47-9. Molecular formula: C23H14F3N5O. Mole weight: 433.39. | |
| DDR2-IN-1 | DDR2-IN-1, a potent DDR2 inhibitor with an IC50 of 26 nM, can be used for osteoarthritis research. Synonyms: 4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide; 2-Pyridinecarboxamide, 4-[4-[[[[[4-chloro-2-[2-(dimethylamino)ethoxy]-5-methylphenyl]amino]carbonyl]amino]methyl]-2-methylphenoxy]-N-methyl-. Grade: ≥97%. CAS No. 1573053-23-2. Molecular formula: C27H32ClN5O4. Mole weight: 526.03. | |
| DDR-TRK-1 | DDR-TRK-1 is a selective inhibitor of Discoidin Domain Receptor 1 (DDR1) (IC50 = 9.4 nM). It also inhibits TRK family. Synonyms: (4R)-N-[3-(4-Methyl-1H-imidazole-1-yl)-5-(trifluoromethyl)phenyl]-2-(5-pyrimidinyl)-4-methyl-1,2,3,4-tetrahydroisoquinoline-7-carboxamide; (R)-4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-2-(pyrimidin-5-yl)-1,2,3,4-tetrahydroisoquinoline-7-carboxamide; DDR1 inhibitor 6j. Grade: ≥95%. CAS No. 1934246-19-1. Molecular formula: C26H23F3N6O. Mole weight: 492.50. | |
| DDT-D8 | DDT-D8 is a labelled Dichlorodiphenyltrichloroethane, which is used as an insecticide. Synonyms: 1,1,1-Trichloro-2,2-bis-(4-chlorophenyl-D4) ethane. Grade: 95% by HPLC; 98% atom D. Molecular formula: C14HD8Cl5. Mole weight: 362.525. | |
| ddTTP | ddTTP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddTTP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dTTP in cells. Uses: Ddttp is an inhibitor of reverse transcriptases from retroviruse. Synonyms: 2',3'-Dideoxythymidine-5'-Triphosphate. Grade: ≥95% by AX-HPLC. CAS No. 611-60-9. Molecular formula: C10H17N2O13P3 (free acid). Mole weight: 466.17 (free acid). | |
| ddTTP-α-S | ddTTP-α-S is used in mass spectrometric genotyping. Synonyms: 2', 3'- Dideoxythymidine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers. Grade: ≥ 95% by HPLC for mixture of Rp-/Sp-isomers. CAS No. 154771-48-9. Molecular formula: C10H17N2O12P3S (free acid). Mole weight: 482.2 (free acid). | |
| ddUDP | ddUDP is a cutting-edge compound, proudly flaunting its title as a modified nucleotide analog. This exceptional creation acts as a premier substrate for none other than DNA polymerases. Synonyms: 2',3'-Dideoxyuridine-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C9H14N2O10P2 (free acid). Mole weight: 372.16 (free acid). | |
| ddUTP | ddUTP, a nucleotide analogue widely employed as a substrate in various molecular biology techniques such as PCR and sequencing, serves as a quintessential tool in studies pertaining to viral replication, cancer research, and drug development for diseases like AIDS. Its incorporation into DNA yields chain termination and evinces promising results in investigating DNA replication and repair mechanisms. Synonyms: ddUTP; dideoxyuridine-triphosphate. Grade: ≥90% by AX-HPLC. CAS No. 84445-38-5. Molecular formula: C9H15N2O13P3 (free acid). Mole weight: 452.14 (free acid). | |
| ddUTP-α-S | ddUTP-α-S is used in mass spectrometric genotyping. Synonyms: 2', 3'- Dideoxyuridine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers (Rp-/Sp-ddUTP-α-S). Grade: ≥ 95% by HPLC for mixture of Rp-/Sp-isomers. CAS No. 1053668-88-4. Molecular formula: C9H15N2O12P3S (free acid). Mole weight: 468.2 (free acid). | |
Our database is helping our users find suppliers everyday.
