BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| D-Arabino-5-hexulosonic acid | D-Arabino-5-hexulosonic acid is an imperative compound used in research of metabolic disorders, diabetes, cardiovascular ailments and neurodegenerative disorders. Synonyms: D-Tagaturonic acid; 5-Keto-L-galactonic acid. CAS No. 6812-1-7. Molecular formula: C6H10O7. Mole weight: 194.14. |  |
| D-Arabinose | D-Arabinose is a natural monosaccharide commonly used in the biomedicine industry. It exhibits potential therapeutic effects for treating various diseases, including diabetes and obesity. This product plays a crucial role in the research and development of antidiabetic drugs, as well as in studying metabolic disorders. Synonyms: (-)-Arabinose; Anhydroarabinose; D-(-)-Arabinose; beta-D-(-)-Arabinose. Grade: ≥98%. CAS No. 10323-20-3. Molecular formula: C5H10O5. Mole weight: 150.13. | |
| D-Arabinose-1,2-13C2 | Isotope labelled analogue of D-Arabinose, an inhibitor of the enzyme glucose dehydrogenase. Synonyms: D-[1,2-13C]Arabinose. Molecular formula: C3[13C]2H10O5. Mole weight: 152.11. | |
| D-Arabinose-13C5 Phenylhydrazone | D-Arabinose-13C5 Phenylhydrazone is a labelled analogue of D-Arabinose Phenylhydrazone, which is a D-Neopterin intermediate. D-Arabinose-13C5 Phenylhydrazone is also an intermediate in the synthesis of D-Neopterin-13C5 which is a labelled precursor in the biosynthesis of Biopterin. First isolated from the pupae of bees. Synonyms: 2-Phenylhydrazone D-Arabinose-13C5; Phenylhydrazone D-Arabinose-13C5. Molecular formula: C6[13C]5H10N2O4. Mole weight: 245.22. | |
| D-Arabinose-5-phosphate | D-Arabinose-5-phosphate is a crucial biochemical compound widely utilized in biomedicine. It plays a vital role in the synthesis of nucleotide sugars necessary for the production of glycoproteins and glycolipids. Synonyms: arabinose 5-phosphate; aldehydo-D-arabinose 5-phosphate; D-A-5-P; D-arabinose, 5-(dihydrogen phosphate). CAS No. 13137-52-5. Molecular formula: C5H11O8P. Mole weight: 230.11. | |
| D-Arabinose-5-phosphate disodium salt | D-Arabinose-5-phosphate disodium salt is a biomedically utilized compound, exhibiting promising attributes in the research of malignant neoplasms and metabolic disorders, namely cancer and diabetes. The incorporation of sodium salt configuration augments solubility and bioaccessibility, thus rendering it highly amenable for pharmaceutical endeavors. CAS No. 89927-09-3. Molecular formula: C5H9Na2O8P. Mole weight: 274.07. | |
| D-Arabinose, (aminothioxomethyl)?hydrazone | D-Arabinose, (aminothioxomethyl)hydrazone, a biomedical substance renowned for its therapeutic applications in combating specific ailments, manifests noteworthy antitumor properties that have been rigorously investigated in the realm of cancer therapy. Synonyms: D-Arabinopyranosyl thiosemicarbazide. CAS No. 154634-27-2. Molecular formula: C6H13N3O4S. Mole weight: 223.25. | |
| D-Arabinose diethyldithioacetal | D-Arabinose diethyldithioacetal is a compound used in biomedicine for various purposes. It has been found to possess potential antidiabetic properties by promoting glucose uptake. Additionally, studies suggest its role as a drug delivery agent for targeted therapies against certain types of cancers. This versatile compound shows promise for further research and development in the biomedical industry. Synonyms: Diethylmercaptal-D-arabinose; D-Arabinose diethyl mercaptal; D-Ribose, diethyl dithioacetal; Arabinose, diethyl mercaptal, D-. CAS No. 1941-50-0. Molecular formula: C9H20O4S2. Mole weight: 256.38. | |
| D-Arabinose phenylhydrazone | D-Arabinose phenylhydrazone, a notable compound extensively employed in the field of biomedicine, holds immense significance. It serves as a vital constituent for investigating and treating a plethora of ailments such as cancer and diabetes. Remarkably, its capacity to impede cancer cell proliferation and govern glucose metabolism underscores its pivotal role in biomedical research. Synonyms: (2R,3S,4R,5E)-5-(2-Phenylhydrazinylidene)pentane-1,2,3,4-tetrol. CAS No. 28767-74-0. Molecular formula: C11H16N2O4. Mole weight: 240.26. | |
| D-Arabonic acid | D-Arabonic Acid is a compound playing a pivotal role in the synthesis of distinguished anti-neoplastic compounds and antibiotics. CAS No. 13752-83-5. Molecular formula: C5H10O6. Mole weight: 166.13. | |
| D-Arabonic acid-1,4-lactone | D-Arabonic acid-1,4-lactone, a paramount compound in the biomedical sector, exhibits immense potential in therapeutic applications. Its exceptional antioxidant characteristics have rendered it a subject of extensive research, particularly concerning cardiovascular illnesses and cancer treatment. Notably, owing to its distinctive chemical configuration, D-Arabonic acid-1,4-lactone showcases remarkable prospects as a targeted drug delivery agent while simultaneously offering effective disease management capabilities. Synonyms: D-Arabino-1,4-lactone. CAS No. 2782-9-4. Molecular formula: C5H8O5. Mole weight: 148.11. | |
| Darapladib | Darapladib (SB-480848) is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.25 nM. Synonyms: SB-480848; SB 480848; SB480848; Darapladib. Grade: >98%. CAS No. 356057-34-6. Molecular formula: C36H38F4N4O2S. Mole weight: 666.77. | |
| Daratumumab | Daratumumab is a recombinant IgG1k monoclonal antibody that binds to CD38 and leads to cell apoptosis. Daratumumab was granted orphan drug designation for the treatment of multiple myeloma, diffuse large B cell lymphoma, follicular lymphoma, and mantle cell lymphoma. Uses: Antitumor agent. Synonyms: Darzalex; HuMax-CD38; UNII-4Z63YK6E0E. CAS No. 945721-28-8. Molecular formula: C6466H9996N1724O2010S42. Mole weight: 145391.67. | |
| Darbufelone mesylate | Darbufelone is a COX-2 inhibitor potentially for the treatment of rheumatoid arthritis. Darbufelone also induces growth inhibition of lung cancer cells both in vitro and in vivo. Darbufelone mesylate is a dual inhibitor of cellular PGF2α and LTB4 production. Synonyms: CI-1004 mesylate; Darbufelone mesilate. Grade: 95%. CAS No. 139340-56-0. Molecular formula: C19H28N2O5S2. Mole weight: 428.57. | |
| Darenzepine | Darenzepine is a muscarinic receptor inhibitor. Synonyms: (E)-1-((5,6-Dihydro-6-oxo-11-morphanthridinylidene)acetyl)-4-methylpiperazine. Grade: 95%. CAS No. 84629-61-8. Molecular formula: C21H21N3O2. Mole weight: 347.41. | |
| D-Arg(10)-ICA | D-Arg(10)-ICA is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: H-D-Arg-Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-D-Arg-OH. Molecular formula: C59H89N19O13S. Mole weight: 1304.52. | |
| D-Arg(28)-Semaglutide | D-Arg(28)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-Arg-28-Semaglutide. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Arg(8)-AVP | D-Arg(8)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Arg(8)-Vasopressin; D-Arg-AVP; Vasopressin, 8-D-arginine-; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-D-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-D-arginyl-glycinamide (1->6)-disulfide; 8-D-Argininevasopressin; D-Arginine-vasopressin; (D-Arg8)vasopressin. CAS No. 5591-81-1. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24. | |
| Darglitazone | Darglitazone is a thiazolidinedione (TZD) which is a proliferator-activated receptor γ (PPARγ) agonist. It increases the sensitivity of cells to insulin, stimulating insulin-induced PI3K activity at submicromolar concentrations by increasing the expression of the p85 subunit of PI3K. Synonyms: CP 86325. Grade: ≥95%. CAS No. 141200-24-0. Molecular formula: C23H20N2O4S. Mole weight: 420.5. | |
| Darifenacin | Darifenacin hydrobromide is an antispasmodic muscarinic antagonist, selective for blocking the M3 muscarinic acetylcholine receptor, which is primarily responsible for bladder muscle contractions. Darifenacin hydrobromide has 9 and 12-fold greater affinity for M3 compared to M1 and M5, respectively, and 59-fold greater affinity for M3 compared to both M2 and M4. Darifenacin is used clinically to treat urinary incontinence and overactive bladder syndrome. Uses: Muscarinic antagonists. Synonyms: UK-88525; UK 88525; UK88525. Grade: >98%. CAS No. 133099-04-4. Molecular formula: C28H30N2O2. Mole weight: 426.55. | |
| Darifenacin Carboxylic Acid Impurity | 2,3-Dihydro-5-benzofuranacetic Acid is a metabolite of Darifenacin. Synonyms: 2,3-Dihydro-5-benzofuranacetic Acid; (2,3-Dihydrobenzofuran-5-yl)acetic Acid; 2,3-Dihydrobenzofuran-5-acetic Acid; 2-(2,3-Dihydrobenzofuran-5-yl)acetic Acid. Grade: > 95%. CAS No. 69999-16-2. Molecular formula: C10H10O3. Mole weight: 178.18. | |
| Darifenacin-d5 | Darifenacin-d5 is a labelled Darifenacin. Darifenacin is a medication used for the treatment of overactive bladder. Grade: > 95%. Molecular formula: C28H25N2O2D5. Mole weight: 431.59. | |
| Darifenacin Hydrobromide | Darifenacin exerts non-parallel rightward displacement of the agonist curve and also significant depression of the maximum response (+)-cis-Dioxolane produced concentration-dependent contraction of the isolated bladder of rat. Uses: Muscarinic antagonists. Synonyms: (3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide Hydrobromide; Enablex; Emselex; (S)-2-(1-(2-(2,3-dihydrobenzofuran-5-yl)ethyl)pyrrolidin-3-yl)-2,2-diphenylacetamide hydrobromide. Grade: >98%. CAS No. 133099-07-7. Molecular formula: C28H30N2O2.HBr. Mole weight: 507.46. | |
| Darifenacin Impurity A | 1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetic Acid is an impurity of Darifenacin, a medication to treat urinary incontinence. It works by blocking the M3 muscarinic acetylcholine receptor. Synonyms: 1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetic Acid. Grade: > 95%. CAS No. 1048979-16-3. Molecular formula: C28H29NO3. Mole weight: 427.53. | |
| Darifenacin Impurity E | 4-[2-di-[2-(2,3-Dihydrobenzofuran-4-yl)ethyl]aminoethyl)-3,3-diphenylpyrolidine-2-one is a cyclic amide impurity of Darifenacin, a medication used to treat urinary incontinence. Synonyms: 4-[2-di-[2-(2,3-Dihydrobenzofuran-4-yl)ethyl]aminoethyl)-3,3-diphenylpyrolidine-2-one; Darifenacin Cyclic Amide. Grade: > 95%. CAS No. 1797983-04-0. Molecular formula: C38H40N2O3. Mole weight: 572.74. | |
| Darifenacin Morpholine Amide Impurity | Darifenacin Morpholine Amide Impurity is an impurity of Darifenacin Morpholine Amide, a medication used for the therapy of overactive bladder syndrome. Synonyms: 2-(2,3-dihydrobenzofuran-5-yl)-1-Morpholinoethanethione. Grade: > 95%. CAS No. 97483-11-9. Molecular formula: C14H17NO2S. Mole weight: 263.36. | |
| Darifenacin N-Oxide | Darifenacin N-Oxide is an impurity of Darifenacin, a medication to treat urinary incontinence. It works by blocking the M3 muscarinic acetylcholine receptor. Synonyms: Darifenacin Impurity C. Grade: > 95%. CAS No. 1391080-40-2. Molecular formula: C28H30N2O3. Mole weight: 442.55. | |
| Darifenacin Pyrrolidinium Dimer Impurity | An impurity of Darifenacin. Darifenacin is a selective muscarinic receptor antagonist used primarily to treat symptoms of overactive bladder, including urge urinary incontinence, urgency, and frequency. Synonyms: Pyrrolidinium, 3-(2-amino-2-oxo-1,1-diphenylethyl)-1,1-bis[2-(2,3-dihydro-5-benzofuranyl)ethyl]-, bromide (1:1), (3S)-; (3S)-3-(2-Amino-2-oxo-1,1-diphenylethyl)-1,1-bis[2-(2,3-dihydro-5-benzofuranyl)ethyl]pyrrolidinium bromide; (S)-3-(2-Amino-2-oxo-1,1-diphenylethyl)-1,1-bis(2-(2,3-dihydrobenzofuran-5-yl)ethyl)pyrrolidin-1-ium bromide; Darifenacin Impurity D; Darifenacin Pyrrolidinium Dimer. Grade: ≥95%. CAS No. 1396968-57-2. Molecular formula: C38H41BrN2O3. Mole weight: 653.66. | |
| Darinaparsin | Darinaparsin is a small-molecule organic arsenical with potential antineoplastic activity. Although the exact mechanism of action is unclear, darinaparsin, a highly toxic metabolic intermediate of inorganic arsenicals (iAs) that occurs in vivo, appears to generate volatile cytotoxic arsenic compounds when glutathione (GSH) concentrations are low. The arsenic compounds generated from darinaparsin disrupt mitochondrial bioenergetics, producing reactive oxygen species (ROS) and inducing ROS-mediated tumor cell apoptosis; in addition, this agent or its byproducts may initiate cell death by interrupting the G2/M phase of the cell cycle and may exhibit antiangiogenic effects. Compared to inorganic arsenic compounds such as arsenic trioxide (As2O3), darinaparsin appears to exhibit a wide therapeutic window. Synonyms: ZIO 101; ZIO101; ZIO-101; SP-02; SP 02; SP02; Zinapar; L-γ-Glutamyl-S-(dimethylarsino)-L-cysteinyl-glycine. CAS No. 69819-86-9. Molecular formula: C12H22AsN3O6S. Mole weight: 411.31. | |
| Darodipine | Darodipine, also known as PY 108-068, is an antagonist of calcium channel. Synonyms: diethyl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; darodipine; PY-108068; PY108068; PY108068; PY108-068; PY-108-068; PY 108-068; Darodipine. CAS No. 72803-02-2. Molecular formula: C19H21N3O5. Mole weight: 371.39. | |
| Darunavir | Darunavir is a second generation protease inhibitor that targets the HIV-1 protease. It demonstrates extremely potent activity against the infectivity and replication of various strains of HIV-1, including several that are resistant to first generation protease inhibitors (IC50s = 3-30 nM). Darunavir has been reported to inhibit both cell-free diffusion and cell-to-cell spread of HIV-1 with IC50 values of 2.5 and 2.8 nM, respectively. Uses: Hiv protease inhibitors. Synonyms: TMC-114; TMC 114; TMC114; Prezista. Grade: ≥98%. CAS No. 206361-99-1. Molecular formula: C27H37N3O7S. Mole weight: 547.67. | |
| Darunavir Ethanolate | Darunavir Ethanolate is a nonpeptidic HIV protease inhibitor, used to treat HIV infection. Uses: Hiv protease inhibitors. Synonyms: Phosphonoformate. Grade: >98%. CAS No. 635728-49-3. Molecular formula: C27H37N3O7S·C2H5OH. Mole weight: 593.73. | |
| Darunavir N-β-D-Glucuronide | Darunavir N-β-D-Glucuronide is a metabolite of Darunavir, an inhibitor of human immunodeficiency virus protease. Synonyms: 1-Deoxy-1-[[4-[[[(2R,3S)-3-[[[[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]amino]-2-hydroxy-4-phenylbutyl](2-methylpropyl)amino]sulfonyl]phenyl]amino]-β-D-glucopyranuronic Acid. Grade: > 95%. CAS No. 1159613-25-8. Molecular formula: C33H45N3O13S. Mole weight: 723.79. | |
| Darunavir-O-Glucuronide | Darunavir-O-Glucuronide is a metabolite of Darunavir, an inhibitor of human immunodeficiency virus protease. Synonyms: Darunavir O-β-D-Glucuronide. Grade: > 95%. CAS No. 1159613-27-0. Molecular formula: C33H45N3O13S. Mole weight: 723.79. | |
| Darusentan | Darusentan is a selective endothelin-1 receptor A inhibitor. Darusentan is identified as the treatment of congestive heart failure, hypertension and cancers. It blocks endothelin ETA receptor thus results in an increase of sodium and potassium excretion in aging rats. Uses: Endothelin receptor antagonists. Synonyms: LU-135252; LU135252; LU 135252; HMR-4005; HMR 4005; HMR4005; (2S)-2-(4,6-dimethoxypyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid. Grade: 95%. CAS No. 171714-84-4. Molecular formula: C22H22N2O6. Mole weight: 410.426. | |
| DASA-58 | DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator. Synonyms: DASA-58; DASA 58; DASA58. Grade: 98%. CAS No. 1203494-49-8. Molecular formula: C19H23N3O6S2. Mole weight: 453.53. | |
| dasabuvir | Dasabuvir is an antiviral drug for the treatment of hepatitis C. It inhibits hepatitis C virus (HCV) non-nucleoside NS5B palm polymerase to suppress RNA replicase. Dasabuvir is commonly used in combination with ombitasvir/paritaprevir/ritonavir to effect on HCV type 1. Uses: The treatment of hepatitis c. Synonyms: ABT333; ABT-333; ABT 333, Dasabuvir. Trade names: Viekira Pak (with ombitasvir/paritaprevir/ritonavir tablets), Exviera; N-(6-(3-(tert-butyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalen-2-yl)methanesulfonamide. Grade: 98.40%. CAS No. 1132935-63-7. Molecular formula: C26H27N3O5S. Mole weight: 493.578. | |
| Dasatinib Carboxylic Acid | Dasatinib Carboxylic Acid is an oxidative metabolite of Dasatinib (M6 metabolite), used in the treatment of cancers and immune diseases. Synonyms: 4-[6-[[5-[[(2-Chloro-6-methylphenyl)amino]carbonyl]-2-thiazolyl]amino]-2-methyl-4-pyrimidinyl]-1-piperazineacetic Acid. Grade: > 95%. CAS No. 910297-53-9. Molecular formula: C22H24ClN7O3S. Mole weight: 501.99. | |
| Dasatinib Dimeric Impurity | Dasatinib Dimeric Impurity is an impurity of Dasatinib (M24 metabolite), used in the treatment of cancers and immune diseases. Synonyms: 2,2'-((6,6'-(Piperazine-1,4-diyl)bis(2-methylpyrimidine-6,4-diyl))bis(azanediyl))bis(N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide). Grade: ≥95%. CAS No. 910297-61-9. Molecular formula: C36H34Cl2N12O2S2. Mole weight: 801.77. | |
| Dasatinib hydrochloride | Dasatinib hydrochloride is a potent and dual Abl/ Src inhibitor. It inhibits c-Kit (WT)/c-Kit (D816V). Synonyms: BMS-354825 hydrochloride; BMS 354825 hydrochloride; BMS354825 hydrochloride; Sprycel hydrochloride. Grade: >98%. CAS No. 854001-07-3. Molecular formula: C22H27Cl2N7O2S. Mole weight: 524.47. | |
| Dasatinib Impurity 5 | Dasatinib Impurity 5 isan impurity of Dasatinib, a targeted therapy for chronic myeloid leukemia and certain types of acute lymphoblastic leukemia. Synonyms: 2-(4-(6-((5-((2-Chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)amino)-2-methylpyrimidin-4-yl)piperazin-1-yl)ethyl acetate. Grade: > 95%. CAS No. 1245157-85-0. Molecular formula: C24H28ClN7O3S. Mole weight: 530.04. | |
| Dasatinib Monohydrate | Dasatinib Monohydrate is a novel, potent and multi-targeted inhibitor that targets Abl, PDGFR, ephrin receptors, Src, c-Kit, and other Src-family kinases (LCK, HCK, FYN, and others). Uses: Antineoplastic agents. Synonyms: BMS-354825 Monohydrate; BMS 354825 Monohydrate; BMS354825 Monohydrate; N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide hydrate. Grade: >98%. CAS No. 863127-77-9. Molecular formula: C22H28ClN7O3S. Mole weight: 506.02. | |
| Dasatinib N-Deshydroxyethyl Impurity | An impurity of Dasatinib, a multi-targeted kinase inhibitor used for for the treatment of Philadelphia chromosome (Ph)-positive leukemias. Synonyms: N-(2-Chloro-6-methylphenyl)-2-((2-methyl-6-(piperazin-1-yl)pyrimidin-4-yl)amino)thiazole-5-carboxamide hydrochloride. CAS No. 1852573-26-2. Molecular formula: C20H23Cl2N7OS. Mole weight: 480.4. | |
| Dasatinib N-Oxide | Dasatinib N-Oxide is an oxidative metabolite of Dasatinib (M5 metabolite). Synonyms: N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide N-Oxide. Grade: > 95%. CAS No. 910297-52-8. Molecular formula: C22H26ClN7O3S. Mole weight: 504. | |
| D-Asn(5)-AVP | D-Asn(5)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Asn-Vasopressin; D-Asn-AVP; H-Cys-Tyr-Phe-Gln-D-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-D-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide; Vasopressin, 5-D-asparagine-8-L-arginine-; 5-D-asparagine-Argipressin. CAS No. 2075715-46-5. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24. | |
| D-Asn5-Carbetocin | An impurity of Carbetocin. Carbetocin is a long-acting analogue of the hormone oxytocin, used primarily to control postpartum hemorrhage and to induce uterine contractions. Synonyms: cyclo(Butyryl-Tyr(Me)-Ile-Gln-DAsn-Cys)-Pro-Leu-Gly-NH2; Carbetocin {d-Asn5}; [D-Asn]5-Carbetocin; [D-Asn5]-Carbetocin; D-Asn(5)-Carbetocin; Glycinamide, N-(4-mercapto-1-oxobutyl)-O-methyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-D-asparaginyl-L-cysteinyl-L-prolyl-L-leucyl-, cyclic (1→5)-thioether; But-Tyr(Me)-Ile-Gln-D-Asn-Cys-Pro-Leu-Gly-NH2 (Thioether bridge: But1-Cys6); Butyryl-O-methyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-D-asparagyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamide (1->6)-thioether; D-[Asn5]-Carbetocin. Grade: ≥95%. CAS No. 1631754-27-2. Molecular formula: C45H69N11O12S. Mole weight: 988.17. | |
| D-Asn 5-Oxytocin | D-Asn 5-Oxytocin is an impurity of Oxytocin, which is a mammalian neurohypophysial hormone used as a vasodilator agent. Synonyms: L-cystyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-D-asparginyl-L-cystyl-L-leucyl-L-prolyl-L-glycinamide (disulfide bridge between cysteines); H-Cys-Tyr-Ile-Gln-D-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Oxytocin, 5-D-asparagine-; [5-D-Asparagine]oxytocin; [D-Asn5]-Oxytocin; L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-D-asparagyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamide (1->6)-disulfide. Grade: ≥95%. CAS No. 5754-53-0. Molecular formula: C43H66N12O12S2. Mole weight: 1007.19. | |
| D-Asn8-Terlipressin | An impurity of Terlipressin. Terlipressin is a synthetic vasopressin analogue primarily used to improve kidney function in adults with hepatorenal syndrome (HRS), a condition that causes kidney problems in individuals with severe liver disease. It acts as a vasoconstrictor, predominantly in the splanchnic circulation, which helps increase arterial pressure and reduce portal venous pressure. Synonyms: Gly-Gly-Gly-Cys-Tyr-Phe-Gln-DAsn-Cys-Pro-Lys-Gly-NH2(Cys4&Cys9 bridge); [D-Asn8]-Terlipressin; D-Asn(8)-Terlipressin; H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-D-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys4-Cys9); Glycyl-glycyl-glycyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-D-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (4->9)-disulfide; GGGCYFQ-DAsn-CPKG-NH2(Cys4&Cys9 bridge). Grade: ≥95%. Molecular formula: C52H74N16O15S2. Mole weight: 1227.37. | |
| D-Asn9-Bivalirudin | D-Asn9-Bivalirudin is a modified form of the anticoagulant Bivalirudin, where the amino acid at the 9th position is replaced with D-asparagine. Bivalirudin is a direct thrombin inhibitor used as an anticoagulant to prevent blood clots in patients undergoing certain medical procedures or with specific conditions. Synonyms: DPhe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-DAsn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu; Bivalirudin D-Asn Impurity; D-Phenylalanyl-L-prolyl-L-arginyl-L-prolylglycylglycylglycylglycyl-D-asparaginylglycyl-L-α-aspartyl-L-phenylalanyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-prolyl-L-α-glutamyl-L-α-glutamyl-L-tyrosyl-L-leucine; DPhe-PRPGGGG-DAsn-GDFEEIPEEYL; H-D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-D-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH; H-{d}FPRPGGGG{d}NGDFEEIPEEYL-OH; [D-Asn9]-Bivalirudin. Grade: ≥95%. CAS No. 1310025-28-5. Molecular formula: C98H138N24O33. Mole weight: 2180.32. | |
| Dasotraline | Dasotraline hydrochloride is a metabolite of sertraline and a novel inhibitor of dopamine and norepinephrine reuptake that blocks dopamine, norepinephrine, andserotonin transporters (IC50= 4, 6, and 11 nM, respectively). Synonyms: (1R,4S)-trans-Norsertraline; Norsertraline, (1R,4S)-trans-; (1R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine. CAS No. 675126-05-3. Molecular formula: C16H15Cl2N. Mole weight: 292.203. | |
| Dasotraline hydrochloride | Dasotraline hydrochloride, also called as SEP-225289 hydrochloride, is a metabolite of Sertraline and a novel inhibitor of dopamine and norepinephrine reuptake that blocks dopamine, norepinephrine, andserotonin transporters (IC50 = 4, 6, and 11 nM, respectively). Synonyms: (1R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine; hydrochloride; SEP-225,289; SEP225,289; SEP225,289; SEP-225289; SEP225289; SEP225289; ; Dasotraline; Dasotraline HCl; Dasotraline hydrochloride. CAS No. 675126-08-6. Molecular formula: C16H16Cl3N. Mole weight: 328.66. | |
| D-Asp4-Eptifibatide | An impurity of Eptifibatide. Eptifibatide is a glycoprotein IIb/IIIa inhibitor used primarily to prevent blood clots in patients with acute coronary syndromes (ACS) and during percutaneous coronary interventions (PCI). Synonyms: Mpr-Har-Gly-DAsp-Trp-Pro-Cys-NH2(Mpr1&Cys7 bridge); Mpr-Har-G-DAsp-WPC-NH2(Mpr&Cys bridge); deamino-Cys-hArg-Gly-D-Asp-Trp-Pro-Cys-NH2 (Disulfide bridge: Cys1-Cys7); Deamino-cysteinyl-L-homoarginyl-glycyl-D-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide (1->7)-disulfide; [D-Asp]4-Eptifibatide; [D-Asp4]-Eptifibatide; D-Asp(4)-Eptifibatide; 4-D-Asp-Eptifibatide; L-Cysteinamide, N-(3-mercapto-1-oxopropyl)-6-[(aminoiminomethyl)amino]-L-norleucylglycyl-D-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→6)-thioether. Grade: ≥95%. CAS No. 3079028-51-3. Molecular formula: C35H49N11O9S2. Mole weight: 831.97. | |
| D-Asp(9)-Semaglutide | D-Asp(9)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: (3S,9S,12S,15S,18S,21R,24S,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Asparaginol | D-Asparaginol is an amino acid derivative presenting a remarkable prowess in studying neurodegenerative afflictions and cancer. Synonyms: Moxifloxacin Impurity 52. Grade: >95% by HPLC. CAS No. 41928-40-9. Molecular formula: C4H10N2O2. Mole weight: 118.13. | |
| DAT-230 | DAT-230 is a promising microtubule inhibitor that has great potential for the treatment of fibrosarcoma in vitro and in vivo. DAT-230 exhibited potent anti-proliferative activity against various cancer cells. DAT-230-treatment in HT-1080 cells resulted in microtubule de-polymerization and G2/M phase arrest preceding apoptosis. Phosphor-cdc2 (thr14/tyr15) reduction, cyclin B1 accumulation and aberrant spindles denoted the cyclin B1-cdc2 complex active and M phase arrest in HT-1080 cells treated with DAT-230. Apoptosis induced by DAT-230 was related with the activation of caspase-9, caspase-3 and PARP cleavage, which were at the downstream of mitochondria. The decrease ratio of Bcl-2/Bax, elevation of NO and disruption of ΔΨm confirmed the causal relationship between DAT-230 and mitochondrial pathway. In vivo, DAT-230 delayed tumor growth, induced tumor perfusion decrease and extensive hemorrhagic-necrosis. Synonyms: DAT 230; DAT230. Grade: 98%. CAS No. 1504583-00-9. Molecular formula: C22H20BrN3O2S. Mole weight: 339.45. | |
| D-Atabrine dihydrochloride | D-Atabrine dihydrochloride is an active enantiomer of quinacrine, which displays antiprion activity. Synonyms: (4S)-N4-(6-Chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-1,4-pentanediamine dihydrochloride; 1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-, (4S)-, hydrochloride (1:2); (S)-quinacrine dihydrochloride. Grade: ≥95%. CAS No. 56100-41-5. Molecular formula: C23H32Cl3N3O. Mole weight: 472.88. | |
| Datelliptium chloride | Datelliptium chloride, derived from ellipticine, is a DNA-intercalating agent with good activity in murine tumor models over a broad range of doses. Synonyms: 2-[2-(diethylamino)ethyl]-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-2-ium-9-ol; chloride; 2-(diethylamino-2-ethyl)-9-hydroxyellipticinium; 2-DEHE; datelliptium chloride; detalliptinium; detalliptinium acetate salt; detalliptinium chloride; detalliptium acetate; diethylaminoethyl-2-OH-9-ellipticinium; NSC 311152; NSC 626718X; NSC-311152; SR 95156A; SR 95156B; SR-95156A. CAS No. 105118-14-7. Molecular formula: C23H28ClN3O. Mole weight: 397.94. | |
| Datelliptium chloride hydrochloride | Datelliptium chloride hydrochloride, a DNA-intercalating agent derived from Ellipticine, is effective against a variety of mouse solid tumors in vivo. Synonyms: 2-(2-(Diethylamino)ethyl)-9-hydroxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-2-ium chloride hydrochloride; 6H-Pyrido[4,3-b]carbazolium, 2-[2-(diethylamino)ethyl]-9-hydroxy-5,11-dimethyl-, chloride, hydrochloride (1:1:1). Grade: ≥95%. CAS No. 157000-76-5. Molecular formula: C23H29Cl2N3O. Mole weight: 434.40. | |
| dA-Thiophosphoramidite | dA-Thiophosphoramidite, a widely utilized chemical compound in the biomedical sector, is an imperative tool employed to fabricate chemically modified oligonucleotides and investigate the complexities of nucleic acids structure and biology. Furthermore, it holds significant value in designing therapeutic medications that selectively target genes responsible for the onset of malignant neoplasms and viral infections. Synonyms: 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyAdenosine, 3'-[(ß-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite. Molecular formula: C51H51N6O7PS2. Mole weight: 955.09. | |
| dATP | dATP is a purine nucleoside triphosphate used in the synthesis of DNA by being incorporated into DNA. Synonyms: 2'-Deoxyadenosine-5'-Triphosphate. Grade: ≥ 95% by HPLC. CAS No. 1927-31-7. Molecular formula: C10H16N5O12P3. Mole weight: 491.18. | |
| dATPαS | dATPαS is a modified nucleotide analog that is widely used as a substrate for various DNA polymerases. It is commonly used in DNA labeling experiments due to its incorporation into target DNA by polymerases during DNA synthesis. It has also been used to generate non-cleavable modified DNA for studying DNA repair mechanisms. Synonyms: 2'-Deoxyadenosine-5'-(α-thio)-triphosphate, Sodium salt (1 : 1 Mixture of Rp and Sp isomers). Grade: ≥ 95% by HPLC. CAS No. 64145-28-4. Molecular formula: C10H16N5O11P3S (free acid). Mole weight: 507.24 (free acid). | |
| dATP solution - Lithium Salt | The lithium salt solution form of dATP. dATP is a purine nucleoside triphosphate used in the synthesis of DNA by being incorporated into DNA. Grade: ≥ 99% by HPLC. Molecular formula: C10H16N5O12P3 (free acid). Mole weight: 491.18 (free acid). | |
| dATP solution - Sodium Salt | The sodium salt solution form of dATP. dATP is a purine nucleoside triphosphate used in the synthesis of DNA by being incorporated into DNA. Grade: ≥ 99% by HPLC. Molecular formula: C10H16N5O12P3 (free acid). Mole weight: 491.18 (free acid). | |
| DAU 5884 hydrochloride | DAU 5884 hydrochloride is a selective muscarinic M3 receptor antagonist. It inhibits methacholine-dependent effects on cell proliferation and muscle contractility in bovine tracheal smooth muscle. Synonyms: DAU 5884 hydrochloride; DAU5884 hydrochloride; DAU-5884 hydrochloride; 8-Methyl-8-azabicyclo-3-endo[3.2.1]oct-3-yl-1,4-dihydro-2-oxo-3(2H)-quinazolinecarboxylic acid ester hydrochloride; [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2-oxo-1,4-dihydroquinazoline-3-carboxylate hydrochloride. Grade: ≥99% by HPLC. CAS No. 131780-48-8. Molecular formula: C17H21N3O3.HCl. Mole weight: 351.83. | |
| Daunomycin | Daunomycin is an intermediate of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: 8-Acetyl-6,10,11-trihydroxy-1-methoxy-5,12-naphthacenedione; 8-Acetyl-6,10,11-trihydroxy-1-methoxytetracene-5,12-dione; 8-Acetyl-5,12-dihydro-6,10,11-trihydroxy-1-methoxynaphthacene-5,12-dione; 5,12-Naphthacenedione, 8-acetyl-6,10,11-trihydroxy-1-methoxy-; Daunorubicin Impurity 5. Grade: ≥95%. CAS No. 20982-41-6. Molecular formula: C21H14O7. Mole weight: 378.33. | |
| Daunomycinone | Daunomycinone is the aglycone core structure of the anthracycline antibiotics daunorubicin and doxorubicin, lacking their sugar moiety. As a key pharmacophore, it contributes to the DNA-intercalating and topoisomerase II inhibition properties of these drugs, enabling anticancer activity. While less potent than the glycosylated forms, daunomycinone retains cytotoxic effects by generating reactive oxygen species (ROS) and disrupting DNA replication. Synonyms: Daunorubicin Impurity A; (8S,10S)-8-Acetyl-6,8,10,11-tetrahydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione; Daunorubicin EP Impurity A; (+)-Daunomycinone; NSC 109531; (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione; Daunomycin Aglicone; Daunomycinon; Daunorubicin Aglycone; Leukaemomycinone C; Daunorubicinone; 5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-, (8S,10S)-; Epirubicin EP Impurity B. Grade: ≥95%. CAS No. 21794-55-8. Molecular formula: C21H18O8. Mole weight: 398.37. | |
| Daunorubicin 4'-O-α-D-Glucoside | Daunorubicin 4'-O-α-D-Glucoside is a derivative of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: (1S,3S)-3-Acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-4-O-β-D-glucopyranuronosyl-α-L-lyxo-hexopyranoside; 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-4-O-β-D-glucopyranuronosyl-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S)-; (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-4-O-α-D-glucopyranuronosyl-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione. CAS No. 229314-80-1. Molecular formula: C33H37NO16. Mole weight: 703.64. | |
| Daunorubicin 4'-O-α-D-Glucoside Sodium Salt | Daunorubicin 4'-O-α-D-glucoside is a derivative of Daunorubicin. Daunorubicin is an anticancer drug that is often used in conjunction with other cytotoxic agents to treat various types of leukemias and carcinomas. Daunorubicin also provides a positive outlook for patients with acute promyelocytic leukemia, inducing remission in about half of the patients. Synonyms: (2S,3S,4S,5R,6S)-6-(((2S,3S,4S,6R)-6-(((1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl)oxy)-4-amino-2-methyltetrahydro-2H-pyran-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate sodium salt; (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-4-O-α-D-glucopyranuronosyl-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Monosodium Salt. CAS No. 229314-76-5. Molecular formula: C33H36NNaO16. Mole weight: 725.63. | |
| Daunorubicin Bromoketal Hydrobromide | Daunorubicin Bromoketal Hydrobromide is a metabolite of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: 14-Bromo Dimethyl Ketal Daunorubicin Hydrobromide; 14-Bromo, 13-Deoxo, 13,13-Dimethoxy Daunorubicin Hydrobromide; Doxorubicin EP Impurity B HBr; (8S,10S)-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(2-bromo-1,1-dimethoxyethyl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrobromide (1:1); (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Hydrobromide; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrobromide, (8S-cis)-. Grade: 85%. CAS No. 148218-14-8. Molecular formula: C29H35Br2NO11. Mole weight: 733.40. | |
| Daunorubicin bromoketal hydrochloride | Daunorubicin bromoketal hydrochloride is a metabolite of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: Daunorubicin bromo dimethyl ketal, hydrochloride; 14-Bromo Dimethyl Ketal Daunorubicin Hydrobromide; Doxorubicin EP Impurity B HCl; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione hydrochloride; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride, (8S-cis)-; (1S,3S)-3-(2-Bromo-1,1-dimethoxyethyl)-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride (1:1). Grade: ≥95%. CAS No. 64291-57-2. Molecular formula: C29H34BrNO11.HCl. Mole weight: 688.94. | |
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