BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
Devapamil is a calcium channel blocker. It blocks the L-type calcium current in an use-dependent manner from the intracellular side of the membrane. Synonyms: 2-(3,4-Dimethoxyphenyl)-2-isopropyl-5-[[2-(3-methoxyphenyl)ethyl]methylamino]valeronitrile. CAS No. 92302-55-1. Molecular formula: C26H36N2O3. Mole weight: 424.6.
Devazepide
Devazepide is a potent and orally active cholecystokinin A(CCK-A) receptor antagonist with IC50 value of 0.26 nM. It is a derivative of benzodiazepine that displays appetite-stimulant effects. It blocks the anorectic response to CCK-8 and increases food intake in rats. It increases appetite and accelerates gastric emptying. It is used as a potential treatment for a variety of gastrointestinal problems including gastroparesis, dyspepsia and gastric reflux. It was developed by Merck Sharp & Dohme and was terminated in clinic phase 2 trials. Uses: Devazepide is used as a potential treatment for a variety of gastrointestinal problems including gastroparesis, dyspepsia and gastric reflux. Synonyms: (3S)-1-Methyl-3-[(1H-indol-2-yl)carbonylamino]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one; L-364718; MK-329; (S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide; MK-329; MK329; N-[(3S)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide. Grade: >99 %. CAS No. 103420-77-5. Molecular formula: C25H20N4O2. Mole weight: 408.45.
Dexamethasone
Dexamethasone is a corticosteroid used to treat inflammatory conditions and antuimmune disorders including endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Synonyms: Dexamethasone sodium phosphate EP Impurity A; Decadron; Maxidex; Hexadecadrol; Dexasone; Aeroseb-Dex; Corson; Cortisumman; Betamethasone EP Impurity A; (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 16α-Methyl-9α-fluoroprednisolone; Dekacort (USP). CAS No. 50-02-2. Molecular formula: C22H29FO5. Mole weight: 392.46.
Dexamethasone 11,21-diacetate
Dexamethasone 11,21-diacetate is an impurity of Desoxymetasone which is an anti-inflammatory agent. Synonyms: (11β,16α)-1,21-bis(acetyloxy)-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione. Grade: 97%. CAS No. 3949-26-6. Molecular formula: C26H33FO7. Mole weight: 476.53.
Dexamethasone-17(20)-enol-21-aldehyde
A degradation and metabolic intermediate of Dexamethasone. Synonyms: (11β,16α)-9-Fluoro-11,20-dihydroxy-16-methyl-3-oxopregna-1,4,17(20)-trien-21-al. Grade: > 95%. CAS No. 6762-51-2. Molecular formula: C22H27FO4. Mole weight: 374.46.
Dexamethasone 17α,21-Ethylorthopropionate
Dexamethasone 17α,21-Ethylorthopropionate is one of Clobetasol propionate intermediates. Clobetasol propionate is a glucocorticoid that induces monooxygenase activity in vivo. It alters the structure of tight junctions in epidermis and smoothened hedgehog pathway receptor agonist. It can be used as an anti-inflammatory, immunosuppressive and antimitotic agent. Active in vivo. Synonyms: (11β,16α)-17,21-[(1-Ethoxypropylidene)bis(oxy)]-9-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione; 9-Fluoro-11β,17,21-trihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione Cyclic 17,21-(Ethyl Orthopropionate); 11β,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione. Grade: 98%. CAS No. 25122-24-1. Molecular formula: C27H37FO6. Mole weight: 476.58.
Dexamethasone-17-ketone (Mixture of 16-alpha and 16-beta methyl Diastereomers)
Renowned as an influential glucocorticoid steroid within the biomedical sector, Dexamethasone-17-ketone serves as an efficacious antidote against inflammation and immunoregulatory responses. Its versatile scope extends to studying diverse afflictions including allergic disorders, endocrine disorders, rheumatic disorders, respiratory diseases and select neoplastic conditions. Grade: > 95%. CAS No. 2285-53-2. Molecular formula: C20H25FO3. Mole weight: 332.42.
Dexamethasone 17-Propionate
Dexamethasone 17-Propionate is a metabolite of Dexamethasone, which is a glucocorticoid used as an anti-inflammatory agent. Uses: A dexamethasone dipropionate metabolite. Synonyms: (11β,16α)-9-Fluoro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)-pregna-1,4-diene-3,20-dione; 9-Fluoro-11β,17,21-trihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione 17-Propionate. Grade: 97%. CAS No. 15423-89-9. Molecular formula: C25H33FO6. Mole weight: 448.52.
Dexamethasone 21-Formate
Dexamethasone 21-Formate is a metabolite of Dexamethasone, which is a glucocorticoid used as an anti-inflammatory agent. Synonyms: (11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl formate; Pregna-1,4-diene-3,20-dione, 9-fluoro-21-(formyloxy)-11,17-dihydroxy-16-methyl-, (11β,16α)-. Molecular formula: C23H29FO6. Mole weight: 420.47.
Dexamethasone 21-Iodide
Dexamethasone 21-Iodide is a derivative of Dexamethasone, which is a glucocorticoid used as an anti-inflammatory agent. Synonyms: 9-Fluoro-11β,17-dihydroxy-21-iodo-16α-methylpregna-1,4-diene-3,20-dione; (11β,16α)-9-Fluoro-11,17-dihydroxy-21-iodo-16-methylpregna-1,4-diene-3,20-dione. Grade: ≥95%. CAS No. 2029-18-7. Molecular formula: C22H28FIO4. Mole weight: 502.36.