BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Edoxaban Impurity 105 (1R,3S,4R) | Edoxaban Impurity 105 (1R,3S,4R) is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Molecular formula: C22H25ClN6O5S. Mole weight: 520.99. |  |
| Edoxaban Impurity 17 | Edoxaban impurity. Synonyms: tert-butyl N-[(1R,2R,5S)-5-(dimethylcarbamoyl)-2-hydroxycyclohexyl]carbamate; Edoxaban Impurity 17; tert-Butyl ((1R,2R,5S)-5-(dimethylcarbamoyl)-2-hydroxycyclohexyl)carbamate; MFCD29037447; SCHEMBL10015599; AMY35572; AKOS025396261; AC-30638; AS-52754; CS-0048040; P15584; tert-Butyl((1R,2R,5S)-5-(dimethylcarbamoyl)-2-hydroxycyclohexyl)carbamate. Grade: > 95%. CAS No. 929693-30-1. Molecular formula: C14H26N2O4. Mole weight: 286.37. | |
| Edoxaban Impurity 3 (1R,2S,5R) Oxalate | Edoxaban Impurity 3 (1R,2S,5R) Oxalate is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Synonyms: tert-butyl ((1R,2S,5R)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate, oxalic acid. Molecular formula: C16H29N3O7. Mole weight: 375.43. | |
| Edoxaban Impurity 35 | Edoxaban Impurity 35 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Synonyms: 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-amine dihydrobromide. CAS No. 852291-41-9. Molecular formula: C7H13N3SBr. Mole weight: 331.07. | |
| Edoxaban Impurity 36 | Edoxaban Impurity 36 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. CAS No. 852291-42-0. Molecular formula: C14H17BrN2S2O3. Mole weight: 405.33. | |
| Edoxaban Impurity 4 (1S,2R,5S) Oxalate | Edoxaban Impurity 4 (1S,2R,5S) Oxalate is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Synonyms: tert-butyl ((1S,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate, oxalic acid. Molecular formula: C16H29N3O7. Mole weight: 375.43. | |
| Edoxaban Impurity 50 | Edoxaban Impurity 50 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Molecular formula: C13H11ClN4O2. Mole weight: 290.71. | |
| Edoxaban Impurity 54 | Edoxaban Impurity 54 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Synonyms: (1S,3R,4R)-4-Amino-3-(boc-amino)-cyclohexanecarboxylic acid ethyl ester. CAS No. 1392745-59-3. Molecular formula: C14H26N2O4. Mole weight: 286.37. | |
| Edoxaban Impurity 58 | Edoxaban Impurity 58 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Synonyms: (1R,3S,4R)-3-(Boc-amino)-4-hydroxy-cyclohexane-carboxylic acid ethyl ester; Ethyl (1R,3S,4R)-3-{[(tert-butoxy)carbonyl]amino}-4-hydroxycyclohexane-1-carboxylate. CAS No. 1392745-22-0. Molecular formula: C14H25NO5. Mole weight: 287.36. | |
| Edoxaban Impurity 62 (1R,2S,4R) | Edoxaban Impurity 62 (1R,2S,4R) is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. CAS No. 2605225-73-6. Molecular formula: C16H22ClN5O3. Mole weight: 367.83. | |
| Edoxaban Impurity 64 | Edoxaban Impurity 64 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. CAS No. 1629245-68-6. Molecular formula: C14H27N3O6S. Mole weight: 365.45. | |
| Edoxaban Impurity 65 | Edoxaban Impurity 65 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. CAS No. 1629245-70-0. Molecular formula: C15H29N3O8S2. Mole weight: 443.53. | |
| Edoxaban Impurity 71 | Edoxaban Impurity 71 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Molecular formula: C24H30ClN7O5S. Mole weight: 564.06. | |
| Edoxaban Impurity 73 | Edoxaban Impurity 73 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Molecular formula: C24H30ClN7O6S. Mole weight: 580.06. | |
| Edoxaban Impurity 80 | Edoxaban Impurity 80 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. CAS No. 2230882-27-4. Molecular formula: C14H27N3O3. Mole weight: 285.39. | |
| Edoxaban Impurity 84 | Edoxaban Impurity 84 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Molecular formula: C12H23N3O3. Mole weight: 257.33. | |
| Edoxaban Impurity 85 | Edoxaban Impurity 85 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Molecular formula: C16H27N3O6. Mole weight: 357.41. | |
| Edoxaban Impurity 87 | Edoxaban Impurity 87 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Molecular formula: C25H33N5O4S. Mole weight: 499.63. | |
| Edoxaban Impurity 88 | Edoxaban Impurity 88 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Synonyms: N1-(3-chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide. Molecular formula: C24H30ClN7O4S. Mole weight: 548.06. | |
| Edoxaban Impurity 89 | Edoxaban Impurity 89 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Synonyms: N1-(4-chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide. Molecular formula: C24H30ClN7O4S. Mole weight: 548.06. | |
| Edoxaban Impurity 90 | Edoxaban Impurity 90 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Synonyms: N1-(6-Chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide. Molecular formula: C24H30ClN7O4S. Mole weight: 548.06. | |
| Edoxaban Impurity 94 | Edoxaban Impurity 94 is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Molecular formula: C20H28N2O6. Mole weight: 392.45. | |
| Edoxaban Impurity C | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Grade: ≥95%. Molecular formula: C9H8Cl2N2O3. Mole weight: 263.07. | |
| Edoxaban Impurity E | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Grade: ≥95%. Molecular formula: C9H9ClN2O3. Mole weight: 228.63. | |
| Edoxaban Impurity F | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Grade: ≥95%. Molecular formula: C9H9ClN2O3. Mole weight: 228.63. | |
| Edoxaban impurity G | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Synonyms: Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4R)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-; N1-(5-Chloro-2-pyridinyl)-N2-[(1S,2R,4R)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide; N-(5-Chloropyridin-2-yl)-N'-[(1S,2R,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide; N1-(5-Chloropyridin-2-yl)-N2-((1S,2R,4R)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide; 4-epi-Edoxaban. Grade: >95%. CAS No. 1255529-26-0. Molecular formula: C24H30ClN7O4S. Mole weight: 548.06. | |
| Edoxaban impurity G tosylate | An impurity of Edoxaban, an oral anticoagulant drug and a direct factor Xa inhibitor. Synonyms: N1-(5-Chloropyridin-2-yl)-N2-((1S,2R,4R)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide 4-methylbenzenesulfonate; Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4R)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, compd. with 4-methylbenzenesulfonate (1:1); N-(5-Chloropyridin-2-yl)-N'-[(1S,2R,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide tosylate. CAS No. 2852734-47-3. Molecular formula: C31H38ClN7O7S2. Mole weight: 720.26. | |
| Edoxaban impurity H | Edoxaban Impurity. Synonyms: N-(5-Chloropyridin-2-yl)-N'-[(1S,2S,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide. Grade: > 95%. CAS No. 1255529-28-2. Molecular formula: C24H30ClN7O4S. Mole weight: 548.06. | |
| Edoxaban Impurity HXZ | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Grade: ≥95%. Molecular formula: C17H24ClN5O5S. Mole weight: 445.92. | |
| Edoxaban impurity I | The enantiomer of Edoxaban, Edoxaban Impurity. Synonyms: N-(5-Chloropyridin-2-yl)-N'-[(1R,2S,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide. Grade: > 95%. CAS No. 1255529-23-7. Molecular formula: C24H30ClN7O4S. Mole weight: 548.07. | |
| Edoxaban Impurity N | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Grade: ≥95%. Molecular formula: C25H35N7O3S2. Mole weight: 545.72. | |
| Edoxaban Impurity O | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Grade: ≥95%. Molecular formula: C24H29Cl2N7O4S. Mole weight: 582.50. | |
| Edoxaban Impurity P | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Grade: ≥95%. Molecular formula: C24H31N7O4S. Mole weight: 513.62. | |
| Edoxaban Impurity Q | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Grade: ≥95%. Molecular formula: C24H30ClN7O4S. Mole weight: 548.06. | |
| Edoxaban Impurity S | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Grade: ≥95%. Molecular formula: C24H30ClN7O5S. Mole weight: 564.06. | |
| Edoxaban Impurity T | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Grade: ≥95%. Molecular formula: C16H27N3O6. Mole weight: 357.41. | |
| Edoxaban methyl impurity | Edoxaban methyl impurity is an impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Synonyms: 2-(((1R,2S,5S)-2-(2-((5-chloropyridin-2-yl)amino)-2-oxoacetamido)-5-(dimethylcarbamoyl)cyclohexyl)carbamoyl)-5,5-dimethyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-5-ium iodide. Molecular formula: C25H33ClIN7O4S. Mole weight: 690.00. | |
| Edoxaban N-Glucuronide | Edoxaban N-Glucuronide is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Molecular formula: C30H38ClN7O10S. Mole weight: 724.18. | |
| Edoxaban N-Oxide | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Synonyms: (5S)-5-Oxide Edoxaban; 2-(((1R,2S,5S)-2-(2-((5-Chloropyridin-2-yl)amino)-2-oxoacetamido)-5-(dimethylcarbamoyl)cyclohexyl)carbamoyl)-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine 5-Oxide. Grade: ≥95%. CAS No. 2244103-96-4. Molecular formula: C24H30ClN7O5S. Mole weight: 564.06. | |
| Edoxaban Oxoacetic Acid Impurity | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Synonyms: Edoxaban metabolite M1; Edoxaban M1 Impurity; 4S-Des-3-chloropyridine Edoxaban. Grade: 95%. CAS No. 767625-11-6. Molecular formula: C19H27N5O5S. Mole weight: 437.52. | |
| Edoxaban (RSS)-Isomer | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Synonyms: Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2S,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-; N1-(5-Chloro-2-pyridinyl)-N2-[(1R,2S,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide; N-(5-Chloropyridin-2-yl)-N'-[(1R,2S,4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide. CAS No. 1255529-25-9. Molecular formula: C24H30ClN7O4S. Mole weight: 548.06. | |
| Edoxaban Tosylate Hydrate | In human plasma, Edoxaban doubles prothrombin time and activates partial thromboplastin time at 0.256 and 0.508 μM, respectively. Synonyms: N-(5-Chloropyridin-2-yl)-N'-((1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl)ethanediamide p-Toluenesulfonate hydrate; N-(5-Chloropyridin-2-yl)-N'-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide mono(p-toluenesulfonate) hydrate; Edoxaban p-toluenesulfonate monohydrate. Grade: >98%. CAS No. 1229194-11-9. Molecular formula: C24H30ClN7O4S.C7H8O3S.H2O. Mole weight: 738.27. | |
| Edoxaban TsOH salt | Edoxaban is an oral factor Xa (FXa) inhibitor, also contraindicated in patients with active pathological bleeding. Uses: A direct factor xa inhibitor. Synonyms: Edoxaban Tosylate; N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide; 4-methylbenzenesulfonic acid. Grade: ≥98%. CAS No. 480449-71-6. Molecular formula: C31H38ClN7O7S2. Mole weight: 720.26. | |
| Edoxudine | Edoxudine, synthesised via organopalladium intermediates, is an antiviral drug. Uses: Antiviral agents. Synonyms: 5-Ethyl-2'-deoxyuridine; EUDR; CCRIS 2349; CCRIS-2349; CCRIS2349; Edoxudina; 1-(2'-deoxy-beta-D-ribofuranosyl)-5-ethyluracil; 2'-deoxy-5-ethyluridine; 5-Ethyl-1-(2'-deoxy-β-D-ribofuranosyl)uracil; 5-Ethyldeoxyuridine; Aedurid; EDU; Epoxudine; β-5-Ethyl-2'-deoxyuridine; β-5-Ethyldeoxyuridine. Grade: ≥95%. CAS No. 15176-29-1. Molecular formula: C11H16N2O5. Mole weight: 256.25. | |
| Edralbrutinib | Edralbrutinib is a potent BTK inhibitor. Synonyms: TG-1701; 4-Amino-3-(4-(2,6-difluorophenoxy)phenyl)-1,6-dihydro-1-((3R)-1-(1-oxo-2-butyn-1-yl)-3-pyrrolidinyl)-7H-pyrrolo(2,3-d)pyridazin-7-one; 7H-Pyrrolo(2,3-d)pyridazin-7-one, 4-amino-3-(4-(2,6-difluorophenoxy)phenyl)-1,6-dihydro-1-((3R)-1-(1-oxo-2-butyn-1-yl)-3-pyrrolidinyl)-; 4-Amino-1-[(3R)-1-(2-butynoyl)-3-pyrrolidinyl]-3-[4-(2,6-difluorophenoxy)phenyl]-1,6-dihydro-7H-pyrrolo[2,3-d]pyridazin-7-one. Grade: ≥98%. CAS No. 1858206-58-2. Molecular formula: C26H21F2N5O3. Mole weight: 489.47. | |
| Edrecolomab | Edrecolomab is a murine monoclonal antibody targeting the cell-surface glycoprotein EpCAM (17-1A), which is expressed on epithelial tissues and on various carcinomas. Edrecolomab may be used in the adjuvant treatment of patients with resected stage III colon cancer. Synonyms: MAb17-1A; Panorex. CAS No. 156586-89-9. | |
| Edrophonium | Edrophonium is a reversible Acetylcholinesterase inhibitor which is effective in avoiding the decomposition of the neurotransmitter acetylcholine competitively so that could be commonly used in the diagnosis of myasthenia gravis and other sorts of disease. Uses: Edrophonium is a reversible acetylcholinesterase inhibitor which is effective in avoiding the decomposition of the neurotransmitter acetylcholine competitively so that could be commonly used in the diagnosis of myasthenia gravis and other sorts of disease. Synonyms: N-Ethyl-3-hydroxy-N,N-dimethyl-benzenaminium Chloride. Grade: > 95%. CAS No. 312-48-1. Molecular formula: C10H16NO+. Mole weight: 166.24. | |
| Edrophonium chloride | Edrophonium chloride is a reversible Acetylcholinesterase inhibitor which is effective in avoiding the decomposition of the neurotransmitter acetylcholine competitively so that could be commonly used in the diagnosis of myasthenia gravis and other sorts o. Uses: Acetylcholinesterase inhibitor which is effective in avoiding the decomposition of the neurotransmitter acetylcholine competitively so that could be commonly used in the diagnosis of myasthenia gravis and other sorts of diseases. Synonyms: ETHYL[M-HYDROXYPHENYL]-DIMETHYLAMMONIUM CHLORIDE; EDROPHONIUM CHLORIDE; antirex; dimethylethyl(m-hydroxyphenyl)-ammoniuchloride; ethyl(m-hydroxyphenyl)dimethyl-ammoniuchloride; n-ethyl-3-hydroxy-n,n-dimethyl-benzenaminiuchloride; tensilon; ethyl(3-hydroxyphenyl. Grade: ≥99%. CAS No. 116-38-1. Molecular formula: C10H16NOCl. Mole weight: 201.69. | |
| Edrophonium-[d5] Chloride | Labelled Edrophonium chloride. Edrophonium chloride is a reversible Acetylcholinesterase inhibitor which is effective in avoiding the decomposition of the neurotransmitter acetylcholine competitively so that could be commonly used in the diagnosis of myasthenia gravis and other sorts of diseases. Synonyms: N-Ethyl-3-hydroxy-N,N-dimethyl-benzenaminium-d5 Chloride; Antirex-d5; Enlon-d5; Reversol-d5; Tensilon-d5; Tensilon-d5 Chloride; Ethyl(m-hydroxyphenyl)dimethylammonium-d5 Chloride. Molecular formula: C10H11D5ClNO. Mole weight: 206.72. | |
| EDTA-C2-dT-CE Phosphoramidite | EDTA-C2-dT-CE Phosphoramidite, a catalyst for biomedical synthesis, is rich in EDTA, ensuring thorough metal ion chelation. Its enhanced stability and selectivity imply potential applications in disease research, including HIV and cancer. Employed mostly in genome editing, it exhibits profound biomedical value through its performance in the synthesis of trace oligonucleotides. Synonyms: 5'-Dimethoxytrityl-5-[N-ethylenediaminetriethylacetate,monoacetylaminoethyl-3-acrylimido]-2'-deoxyUridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C60H81N8O16P. Mole weight: 1201.32. | |
| EED-226 | EED-226 is a novel allosteric Polycomb repressive complex 2 (PRC2) inhibitor (IC50 = 23.4 nM when the substrate is H3K27me0 peptide and IC50 = 53.5 nM when the substrate is mononucleosom). EED-226 induces a conformational change via binding EED which invalidates PRC2 activity. PRC2 plays pivotal roles in transcriptional regulation. EED-226 has the potential to treat PRC2-dependent cancers, such as human lymphoma xenograft tumors. Synonyms: EED226; EED-226; EED 226. N-(2-furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-1,2,4-triazolo[4,3-c]pyrimidin-5-amine. Grade: 98%. CAS No. 2083627-02-3. Molecular formula: C17H15N5O3S. Mole weight: 369.4. | |
| EEDi-5273 | EEDi-5273 is a particularly potent and orally efficacious EED inhibitor (IC50 = 0.2 nM) that achieves complete and sustained tumor regression. Synonyms: 12-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)-4-isopropyl-7-(trifluoromethyl)-4,5-dihydro-3H-2,4,8,11,12a-pentaazabenzo[4,5]cycloocta[1,2,3-cd]inden-3-one. CAS No. 2585648-55-9. Molecular formula: C26H22F4N6O2. Mole weight: 526.49. | |
| EEDi-5285 | EEDi-5285 is a particularly potent and orally active inhibitor of embryonic ectoderm development (EED) with an IC50 of 0.2 nM for binding to EED protein. It has anticancer activity. In the Pfeiffer and KARPAS422 lymphoma cell lines with EZH2 mutations, it inhibits cell growth with IC50s of 20 pM and 0.5 nM, respectively. Synonyms: 8-(6-cyclopropylpyridin-3-yl)-N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-1-(methylsulfonyl)imidazo[1,5-c]pyrimidin-5-amine. Grade: ≥95%. CAS No. 2488952-40-3. Molecular formula: C24H22FN5O3S. Mole weight: 479.53. | |
| EED ligand 1 | EED ligand 1 is a diverse, potent and effective inhibitor that targets the EED subunit of the polycomb repressive complex 2 (PRC2) methyltransferase. Synonyms: N5-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-N8-methyl-N8-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-c]pyrimidine-5,8-diamine. Molecular formula: C19H19FN8O. Mole weight: 394.41. | |
| Eeyarestatin I | Eeyarestatin I is a potent inhibitor of endoplasmic reticulum associated protein degradation (ERAD). Eeyarestatin I suppresses ataxin-3 (atx3)-dependent deubiquitination targeting the p97-associated deubiquinating process (PAD). It also inhibits Sec61-mediated protein translocation at the ER. Eeyarestatin I exhibits cytotoxic activity against cancer cells. Synonyms: 3-(4-Chlorophenyl)-4-[[[(4-chlorophenyl)amino]carbonyl]hydroxyamino]-5,5-dimethyl-2-oxo-1-imidazolidineacetic acid 2-[3-(5-nitro-2-furanyl)-2-propen-1-ylidene]hydrazide. Grade: ≥98% by HPLC. CAS No. 412960-54-4. Molecular formula: C27H25Cl2N7O7. Mole weight: 630.44. | |
| Efalizumab | Efalizumab is an anti-CD11a monoclonal antibody that has been approved for the treatment of psoriasis. Synonyms: Hu 1124; Raptiva; Xanelim. Grade: 95%. CAS No. 214745-43-4. | |
| Efaproxiral | synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen binding affinity. Increasing tumor oxygenation reduces tumor radioresistance. One use for efaproxiral is to increase the efficacy of certain chemotherapy drugs which have reduced efficacy against hypoxic tumours, and can thus be made more effective by increased offloading of oxygen into the tumour tissues. However, no benefit was seen for efaproxiral in phase III clinical trials. Synonyms: RSR13; RSR-13; RSR 13; Efaproxyn; NSC722758; (24(35dimethylanilino)carbonylmethylphenoxyl2methylproprionic acid sodium salt. CAS No. 131179-95-8. Molecular formula: C20H23NO4. Mole weight: 341.4. | |
| Efaproxiral Sodium | Efaproxiral, a synthetic allosteric modi?er of hemoglobinoxygen binding af?nity, has been shown to bind reversibly to hemoglobin, stabilizing the deoxyhemoglobin tetramer conformation to reduce its af?nity for oxygen. Synonyms: Efaproxiral sodium; 170787-99-2; RSR13 SODIUM; Sodium 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanoate; Efaproxiral (sodium); Efaproxiral sodium [USAN]; RSR-13 SODIUM; 3L83QP52XI; 170787-99-2 (sodium); Efaproxyn; Efaproxiral sodium (USAN); Sodium 2-[4-[2-[(3,5-dimethylphenyl)amino]-2-oxoethyl]phenoxy]-2-methylpropanoate; Propanoic acid, 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methyl-, monosodium salt; Efaproxiral Sodium. Grade: >98%. CAS No. 170787-99-2. Molecular formula: C20H23NO4.Na. Mole weight: 363.38. | |
| Efaroxan hydrochloride | Efaroxan hydrochloride is a potent and selective α2 adrenoceptor antagonist and imidazoline I1 receptor ligand (pKi = 7.87, 7.42, 5.74, 7.28 and < 5 for α 2A, α2B, α2C, I1, and I2 receptors, respectively). Efaroxan promotes insulin secretion, at a site distinct from I1 or I2 (the putative I3 receptor) in vitro and in vivo. Synonyms: Efaroxan HCl; RX 821037A; RX821037A; RX-821037A; EU-0100521; EU0100521; EU 0100521; 2-(2-Ethyl-2,3-dihydro-2-benzofuranyl)-4,5-dihydro-1H-imidazole hydrochloride. Grade: ≥99% by HPLC. CAS No. 89197-00-2. Molecular formula: C13H16N2O.HCl. Mole weight: 252.74. | |
| Efavirenz amino alcohol bis(ethoxycarbonyl) | An impurity of Efavirenz. Efavirenz is an antiretroviral medication used for the treatment of HIV/AIDS. Molecular formula: C19H19ClF3NO5. Mole weight: 433.81. | |
| Efavirenz amino alcohol ethyl carbamate | An impurity of Efavirenz. Efavirenz is an antiretroviral medication used for the treatment of HIV/AIDS. Synonyms: [4-Chloro-2-[(1S)-3-cyclopropyl-1-hydroxy-1-(trifluoromethyl)-2-propynyl]phenyl]-carbamic Acid Ethyl Ester; Ethyl [4-Chloro-2-((1S)-1-trifluoromethyl-1-hydroxy-3-cyclopropyl-2-propyn-1-yl)phenyl]carbamate. CAS No. 211563-41-6. Molecular formula: C16H15ClF3NO3. Mole weight: 361.74. | |
| Efavirenz amino alcohol methyl carbamate | An impurity of Efavirenz. Efavirenz is an antiretroviral medication used for the treatment of HIV/AIDS. Synonyms: Methyl [4-Chloro-2-((1S)-1-trifluoromethyl-1-hydroxy-3-cyclopropyl-2-propyn-1-yl)phenyl]carbamate. Grade: 95%. CAS No. 211563-40-5. Molecular formula: C15H13ClF3NO3. Mole weight: 347.719. | |
| Efavirenz benzoylaminoalcohol | An impurity of Efavirenz. Efavirenz is an antiretroviral medication used for the treatment of HIV/AIDS. Synonyms: Efavirenz 4-methoxybenzoylaminoalcohol; (S)-N-(4-Chloro-2-(4-cyclopropyl-1,1,1-trifluoro-2-hydroxybut-3-yn-2-yl)phenyl)-4-methoxybenzamide. CAS No. 353270-77-6. Molecular formula: C21H17ClF3NO3. Mole weight: 423.82. | |
| Efavirenz Benzoylaminoalcohol Impurity | An impurity arising in the synthesis of Efavirenz. Synonyms: rac N-[4-Chloro-2-[3-cyclopropyl-1-hydroxy-1-(trifluoromethyl)-2-propynyl]phenyl]-4-methoxybenzamide. Grade: > 95%. CAS No. 1189491-03-9. Molecular formula: C21H17ClF3NO3. Mole weight: 423.81. | |
| Efavirenz cyclobutenylindole analog | An impurity of Efavirenz. Efavirenz is an antiretroviral medication used for the treatment of HIV/AIDS. Synonyms: ethyl 5-chloro-2-cyclobutenyl-3-(trifluoromethyl)-1H-indole-1-carboxylate. Molecular formula: C16H13ClF3NO2. Mole weight: 343.73. | |
| Efavirenz impurity (6-chloro-4-[2-(2-methylcyclopropyl)ethynyl]-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one) | Efavirenz impurity (6-chloro-4-[2-(2-methylcyclopropyl)ethynyl]-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one) is an impurity of Efavirenz, a medication used to treat HIV/AIDS. Grade: > 95%. CAS No. 1217623-65-8. Molecular formula: C15H11ClF3NO2. Mole weight: 329.71. | |
| Efavirenz impurity (6-chloro-4-(pent-1-ynyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one) | 6-chloro-4-(pent-1-ynyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one, recognized as a vital entity in the research of biomedical sciences, holding substantial significance. It finds utility in the fractional supervision and exploration endeavors pertaining to Efavirenz, an antiviral compound enlisted in the study against HIV/AIDS. Grade: > 95%. CAS No. 1627575-36-3. Molecular formula: C14H11ClF3NO2. Mole weight: 317.7. | |
| Efavirenz pent-3-ene-1-yne (cis) | An impurity of Efavirenz. Efavirenz is an antiretroviral medication used for the treatment of HIV/AIDS. Synonyms: (Z)-efavirenz pent-3-ene-1-yne; (S,Z)-6-Chloro-4-(pent-3-EN-1-ynyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Molecular formula: C14H9ClF3NO2. Mole weight: 315.67. | |
| Efavirenz pent-3-ene-1-yne (trans) | An impurity of Efavirenz. Efavirenz is an antiretroviral medication used for the treatment of HIV/AIDS. Synonyms: (E)-efavirenz pent-3-ene-1-yne; (S,E)-6-Chloro-4-(pent-3-EN-1-ynyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Molecular formula: C14H9ClF3NO2. Mole weight: 315.67. | |
| Efavirenz penteneyne | An impurity of Efavirenz. Efavirenz is an antiretroviral medication used for the treatment of HIV/AIDS. Synonyms: (S)-6-chloro-4-(3-methylbut-3-en-1-ynyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Molecular formula: C14H9ClF3NO2. Mole weight: 315.67. | |
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