BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Estradiol 3-sulfamate | Estradiol 3-sulfamate, also known as J 995 or BLE 00084, is a potent, long-acting, and orally active steroid sulfatase inhibitor (IC50= 251 nM, and Ki= 133 nM for estrone sulfatase) to reach Phase ? clinical research for the treatment of endometriosis. Synonyms: [(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] sulfamate; E2MATE cpd; estradiol-3-O-sulfamate. CAS No. 172377-52-5. Molecular formula: C18H25NO4S. Mole weight: 351.46. |  |
| Estradiol 3-sulfate 17b-glucuronide dipotassium salt | Introducing Estradiol 3-sulfate 17b-glucuronide dipotassium salt is a profoundly efficacious steroid compound playing a pivotal role as an estrogen receptor agonist. This compoundously versatile substance is used in the research of hormone therapy and estrogen-dependent afflictions. Synonyms: (17b)-3-(Sulfooxy)estra-1,3,5(10)-trien-17-yl b-D-glucopyranosiduronic acid dipotassium salt. CAS No. 10392-35-5. Molecular formula: C24H30K2O11S. Mole weight: 604.75. | |
| Estradiol Benzoate Impurity E | An impurity of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: 17-epi- Estradiol Benzoate. Grade: > 95%. CAS No. 6045-53-0. Molecular formula: C25H28O3. Mole weight: 376.50. | |
| Estradiol-d3 Glucuronide | One of the isotope labelled derivative of Estradiol, which is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: (17β)-3-Hydroxyestra-1,3,5(10)-trien-17-yl β-D-Glucopyranosiduronic Acid-d3. Molecular formula: C24H29O8D3. Mole weight: 451.54. | |
| Estradiol Enanthate Acetate | A derivative of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: (8R,9S,13S,14S,17R)-3-acetoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-yl heptanoate. Grade: > 95%. Molecular formula: C27H38O4. Mole weight: 426.60. | |
| Estradiol Glucuronide | A derivative of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: Estradiol 3-O-β-D-glucuronide; (17β)-17-Hydroxyestra-1,3,5(10)-trien-3-yl β-D-glucopyranosiduronic acid; 17β-Hydroxyestra-1,3,5(10)-trien-3-yl β-D-glucosiduronic acid; 17β-Estradiol 3-glucosiduronate; 17β-Estradiol 3-glucuronide; Estradiol 3-glucosiduronate; Estradiol 3-glucuronide; Estradiol-17β-3-(β-D-glucuronide). Grade: ≥95%. CAS No. 15270-30-1. Molecular formula: C24H32O8. Mole weight: 448.52. | |
| Estradiol Hemihydrate Impurity D | An impurity of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: delta9,11-Estradiol. Grade: > 95%. CAS No. 791-69-5. Molecular formula: C18H22O2. Mole weight: 270.37. | |
| Estradiol Impurity C | An impurity of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: 4-Methyl Estradiol. Grade: > 95%. CAS No. 6171-48-8. Molecular formula: C19H26O2. Mole weight: 286.42. | |
| Estradiol related compound B | An impurity of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: (17β)-Estra-1,3,5(10),6-tetraene-3,17-diol; Estra-1,3,5(10),6-tetraene-3,17β-diol; 6-Dehydroestradiol. Grade: > 95%. CAS No. 7291-41-0. Molecular formula: C18H22O2. Mole weight: 270.37. | |
| Estradiol Valerate Impurity C | An impurity of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: ?9,11-Dehydro-17β-estradiol 17-valerate. Grade: > 95%. CAS No. 95959-20-9. Molecular formula: C23H30O3. Mole weight: 354.49. | |
| Estramustine | Estramustine, a derivative of estradiol, is an alkylating antineoplastic agent that is used in the treatment of prostate cancer throughout the world. Uses: Used treatment of breast cancer. also used in the treatment of prostate cancer. Synonyms: Estramustine; NSC 89201; NSC-89201; NSC89201; LEO 275; LEO-275; LEO275; RO 21-8837; [(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] N,N-bis(2-chloroethyl)carbamate. Grade: ≥98%. CAS No. 2998-57-4. Molecular formula: C23H31Cl2NO3. Mole weight: 440.4. | |
| Estramustine phosphate sodium | Estramustine phosphate sodium is an antimicrotubule chemotherapy agent. It arrests prostate cancer cells in the G2/M phase of the cell cycle. Uses: Antineoplastic agents, hormonal. Synonyms: estramustine Phosphate, Emcyt, Estracyt, Leo-299; Ro 22-2296/000. Grade: >98%. CAS No. 52205-73-9. Molecular formula: C23H30Cl2NNa2O6P. Mole weight: 564.347. | |
| Estriol | Estriol is a metabolite of 17β-estradiol with much lower biological activity. It is the primary estrogen found in the urine. Large quantities of estriol and estrone are produced by the placenta during pregnancy. These are also the primary estrogens produced by adipose tissue in men and in post-menopausal women. Synonyms: 16α-hydroxy-17β-estradiol; 1,3,5(10)-Estratriene-3,16α, 17β-triol; E3; Oestriol; Ovestin; Estratriol; Ovestrion. Grade: 0.98. CAS No. 50-27-1. Molecular formula: C18H24O3. Mole weight: 288.387. | |
| Estriol 16-alpha-(beta-D-Glucuronide)-d5 | One of the isotopic labelled impurities of Estriol, which is an estrogenic metabolite. Synonyms: 1,3,5(10)-Estratrien-3,16-alpha, 17-beta-triol 16-glucosiduronate-d5. Molecular formula: C24H27O9D5. Mole weight: 469.55. | |
| Estriol 3-(beta-D-Glucuronide)-d5 | One of the isotopic labelled impurities of Estriol, which is an estrogenic metabolite. Synonyms: 16α,17β-Dihydroxyestra-1,3,5(10)-trien-3-yl β-D-Glucopyranosiduronic Acid-d5. Molecular formula: C24H27O9D5. Mole weight: 469.55. | |
| Estriol 3-O-b-D-glucuronide sodium salt | Estriol 3-O-b-D-glucuronide sodium salt, an indispensable constituent within the biomedical sector, finds its application in diverse hormonally-induced ailments, encompassing menopausal manifestations and hormonally-specific malignancies. An augmented stability and convenient formulation for pharmaceutical purposes are conferred by this derivative with sodium salt composition. Embodied with profound remedial attributes, Estriol 3-O-b-D-glucuronide sodium salt emerges as a pivotal agent in the realms of biomedical inquiry and pharmacological advancement. Synonyms: Estriol 3-(beta-D-glucuronide) sodium salt; Estriol 3-O-beta-D-glucuronide sodium salt. CAS No. 15087-06-6. Molecular formula: C24H31NaO9. Mole weight: 486.49. | |
| Estriol-3-Sulfate-16-alpha-(beta-D-Glucuronide)-d5 | One of the isotope labelled impurities of Estriol, which is an estrogenic metabolite. Synonyms: b-D-Glucopyranosiduronic acid, (16a,17b)-17-hydroxy-3-(sulfooxy)estra-1,3,5(10)-trien-16-yl-d5. Molecular formula: C24H27O12SD5. Mole weight: 549.61. | |
| Estriol 3-Sulfate-d5 | One of the isotope labelled impurities of Estriol, which is an estrogenic metabolite. Synonyms: 16alpha-Hydroxyestradiol 3-sulfate-d5. Molecular formula: C18H19O6SD5. Mole weight: 373.48. | |
| Estriol Impurity A | An impurity of Estriol. Estriol is one of the three main estrogens produced by the human body. Synonyms: 9,11-Didehydroestriol ; Estra-1,3,5(10),9(11)-tetraene-3,16α,17β-triol. Grade: > 95%. CAS No. 246021-20-5. Molecular formula: C18H22O3. Mole weight: 286.37. | |
| Estriol Impurity C | An impurity of Estriol. Estriol is one of the three main estrogens produced by the human body. Synonyms: Estriol 3-Methyl Ether ; 3-Methoxyestra-1,3,5(10)-triene-16α,17β-diol. Grade: > 95%. CAS No. 18650-87-8. Molecular formula: C19H26O3. Mole weight: 302.42. | |
| Estriol Impurity E | An impurity of Estriol. Estriol is one of the three main estrogens produced by the human body. Synonyms: 17-epi-Estriol ; Estra-1,3,5(10)-triene-3,16α,17α-triol. Grade: > 95%. CAS No. 1228-72-4. Molecular formula: C18H24O3. Mole weight: 288.39. | |
| Estriol Impurity F | An impurity of Estriol. Estriol is one of the three main estrogens produced by the human body. Synonyms: 16-epi-Estriol ; Estra-1,3,5(10)-triene-3,16β,17β-triol. Grade: > 95%. CAS No. 547-81-9. Molecular formula: C18H24O3. Mole weight: 288.39. | |
| Estriol Impurity G | An impurity of Estriol. Estriol is one of the three main estrogens produced by the human body. Synonyms: 16,17-epi-Estriol ; Estra-1,3,5(10)-triene-3,16β,17α-triol. Grade: > 95%. CAS No. 793-89-5. Molecular formula: C18H24O3. Mole weight: 288.39. | |
| Estrogen receptor modulator 6 | Estrogen receptor modulator 6, a selective agonist of estrogen receptor β (ERβ) (Ki = 0.44 nM), shows 19-fold selectivity for ERβ over ERα (Ki = 8.4 nM). Synonyms: Cyclopenta[c][1]benzopyran-8-ol, 2,2-difluoro-1,2,3,3a,4,9b-hexahydro-4-(4-hydroxyphenyl)-, (3aS,4R,9bR)-; (3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol. CAS No. 787621-78-7. Molecular formula: C18H16F2O3. Mole weight: 318.31. | |
| Estrone 3-3' Dimer | A dimer of Estrone. Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol. Synonyms: Estra-1,3,5(10)-trien-17-one, 3,3'-oxybis-; 3,3'-Oxybis[estra-1,3,5(10)-trien-17-one]; (8R,8'R,9S,9'S,13S,13'S,14S,14'S)-3,3'-Oxybis(13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one). Grade: ≥95%. CAS No. 1089705-14-5. Molecular formula: C36H42O3. Mole weight: 522.73. | |
| Estrone-3-Glucuronide (Estrone beta-D-Glucuronide) | A derivative of Estrone. Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol. Synonyms: Estrone 3-O-β-D-glucuronide; 17-Oxoestra-1,3,5(10)-trien-3-yl β-D-glucopyranosiduronic acid; Estrone glucosiduronate; Estrone glucuronide; Estrone monoglucosiduronate; Estrone monoglucuronide; Estrone β-D-glucuronide; Estrone β-glucuronide. Grade: ≥95%. CAS No. 2479-90-5. Molecular formula: C24H30O8. Mole weight: 446.50. | |
| Estrone 3-Sulfate Sodium Salt | A derivative of Estrone. Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol. Synonyms: 3-(Sulfooxy)-estra-1,3,5(10)-trien-17-one, sodium salt; NSC 18313; Estra-1,3,5(10)-trien-17-one, 3-(sulfooxy)-, sodium salt (1:1); Estrone 3-O-sulfate, sodium salt; Estrone sulfate sodium salt; Estrone, hydrogen sulfate sodium salt; 3-Sulfatoxyestra-1,3,5(10)-trien-17-one sodium salt; Conestoral; Estrone sodium sulfate; Estrone sulfate sodium; Morestin; Sodium estrone sulfate; Sodium estrone-3-sulfate. Grade: ≥95%. CAS No. 438-67-5. Molecular formula: C18H21NaO5S. Mole weight: 372.41. | |
| Estrone Acetate | A derivative of Estrone. Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol. Synonyms: Estra-1,3,5(10)-trien-17-one, 3-(acetyloxy)-; 17-oxoestra-1,3,5(10)-trien-3-yl acetate; (13alpha,14beta)-17-oxoestra-1,3,5(10)-trien-3-yl acetate. Grade: > 95%. CAS No. 901-93-9. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Estrone b-D-glucuronide sodium salt | Estrone b-D-glucuronide sodium salt, an indispensable pharmaceutical compound vital in the biomedical sector, plays a pivotal role in elucidating the intricate mechanisms underlying steroid hormones and their glucuronidation. Esteemed for its profound research utility, this sodium salt entity unveils a profound understanding of estrone's metabolism and elimination pathways, thereby paving the way for comprehensive investigations into hormone-related malignancies and associated pathologies. Synonyms: Estrone beta-D-glucuronide sodium salt; Sodium Estrone Glucuronide; 1,3,5(10)-Estratrien-17-one 3-glucuronide sodium salt. CAS No. 15087-01-1. Molecular formula: C24H29NaO8. Mole weight: 468.47. | |
| Estrone-d4-3-glucuronide | One of the isotope labelled impurities of Estrone, which is one of the major estrogens secreted by the ovary. Synonyms: 17-Oxoestra-1,3,5(10)-trien-3-yl β-D-Glucopyranosiduronic Acid-d4. Molecular formula: C24H26O8D4. Mole weight: 450.53. | |
| Estrone-[d5] b-D-glucuronide | Estrone-[d5] b-D-glucuronide. Synonyms: Estrone D5 b-D-glucuronide. Molecular formula: C24D5H25O8. | |
| Estropipate | Estropipate is an estrogen receptor agonist used in post-menopausal women for hormonal replacement therapy, with benefits to improved cognition and prevention of osteoporosis. Also inhibits organic anion transporting polypeptide 1B1 (OATP1B1) (IC50= 70 nM. Uses: Used in post-menopausal women for hormonal replacement therapy, with benefits to improved cognition and prevention of osteoporosis. Synonyms: Piperazine estrone sulfate; 3-Sulfatoxyestra-1,3,5(10)-trien-17-one piperazine Salt. Grade: ≥96%. CAS No. 7280-37-7. Molecular formula: C18H22O5S.C4H10N2. Mole weight: 436.56. | |
| ETA antagonist 1 | ETA antagonist 1 is a selective endothelin A (ETA) receptor antagonist with an IC50 of 0.08 μM. Synonyms: 5-Pentylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide; N-(3,4-Dimethyl-1,2-oxazol-5-yl)-5-(pentylamino)-1-naphthalenesulfonamide; 1-Naphthalenesulfonamide, N-(3,4-dimethyl-5-isoxazolyl)-5-(pentylamino)-. Grade: ≥95%. CAS No. 161801-60-1. Molecular formula: C20H25N3O3S. Mole weight: 387.50. | |
| Etafedrine HCl (Ethylephedrine HCl) | Etafedrine or ethylephedrine is a long-acting bronchodilator. It was previously commercially available as both the free base and as the hydrochloride salt. Synonyms: Etafedrine hydrochloride; α-[1-(Ethylmethylamino)ethyl]benzenemethanol Hydrochloride; α-[1-(Ethylmethylamino)ethyl]benzyl Alcohol Hydrochloride. Grade: > 95%. CAS No. 5591-29-7. Molecular formula: C12H19NO.HCl. Mole weight: 229.75. | |
| Etalocib | LY293111, a novel diaryl ether carboxylic acid derivative, is a potent and selective inhibitor of the lipoxygenase pathway either directly through 5'-lipoxygenase or via antagonism of the leukotriene B4 (LTB4) receptor. LY293111 has antineoplastic activity in a variety of preclinical models. Synonyms: LY293111; VML 295; 2-[3-[3-[(5-Ethyl-4'-fluoro-2-hydroxy[1,1'-biphenyl]-4-yl)oxy]propoxy]-2-propylphenoxy]benzoic Acid; 2-[2-Propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5-hydroxyphenoxy]propoxy]phenoxy]benzoic acid. Grade: ≥98%. CAS No. 161172-51-6. Molecular formula: C33H33FO6. Mole weight: 544.61. | |
| Etamicastat | Etamicastat is a selective dopamine β-hydroxylase (DBH) inhibitor. etamicastat can effectively decrease blood pressure, although can not prevent the development of hypertension in the spontaneously hypertensive rat. In Aug 2016, Phase-II for Hypertension in France was discontinued. Uses: Heart failure; hypertension. Synonyms: (R)-5-(2-aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydro-2H-imidazole-2-thione; BIA 5-453; 677773-32-9 (HCl salt). Grade: 98%. CAS No. 760173-05-5. Molecular formula: C14H15F2N3OS. Mole weight: 311.35. | |
| Etamicastat HCl salt | Etamicastat HCl salt is a potent, peripherally selective, reversible, dopamine β-hydroxylase inhibitor (DBH inhibitor). It effectively decreases blood pressure, although does not prevent the development of hypertension in the spontaneously hypertensive rat. It was developed by Bial-Portela and was in clinic phase 2 trials, but now it is terminated. Uses: Etamicastat hcl salt effectively decreases blood pressure, although does not prevent the development of hypertension in the spontaneously hypertensive rat. Synonyms: BIA5-453 HCl salt; BIA-5-453 HCl salt; (R)-5-(2-aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydro-2H-imidazole-2-thione hydrochloride. Grade: 98%. CAS No. 677773-32-9. Molecular formula: C14H16ClF2N3OS. Mole weight: 347.81. | |
| Etamsylate | Ethamsylate is a haemostatic drug, which inhibits biosynthesis and action of prostaglandins, and increases capillary endothelial resistance and platelet adhesion. Synonyms: E 141; MD 141; E141; MD141; E-141; MD-141; Aglumin; Altodor; Eselin. Grade: >98%. CAS No. 2624-44-4. Molecular formula: C6H6O5S.C4H11N. Mole weight: 263.31. | |
| Etanercept | Etanercept inhibits in vitro the activity of human TNF and is efficacious in many in vivo models of inflammation, including arthritis. Etanercept competitively inhibits the binding of both TNF-α and TNF-β (lymphotoxin-α) to cell surface TNF receptors, rendering TNF biologically inactive. It also modulates indirectly different biological responses that are induced or regulated by TNF, such as the expression of adhesion molecules E-selectin and to a lesser extent intercellular adhesion molecule 1 (ICAM-1), the production of interleukin-6 (IL-6) and matrix metalloproteinase 3 (MMP-3) (stromelysin), as well as IL1. Synonyms: 1-235-Tumor necrosisfactor receptor (human) fusion protein with 236-467-immunoglobulin G1 (human g1-chain Fc fragment); TNFR-Fc fusion protein; Etanercept; Embrel; Enbrel; rhu-TNFR-Fc. Grade: 95%. CAS No. 185243-69-0. Molecular formula: C2224H3472N618O701S36. | |
| Etanidazole (SR-2508) | Etanidazole (SR-2508) is a 2-nitroimidazole drug with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the cytotoxicity of ionizing radiation. This agent may also be useful as an imaging agent for identifying hypoxic, drug-resistant regions of primary tumors or metastases. Uses: Radiation-sensitizing agents. Synonyms: N-(2-Hydroxyethyl)-2-nitro-1H-imidazole-1-acetamide; N-(2-Hydroxyethyl)-2-nitroimidazole-1-acetamide; NSC 301-467; Radinyl; SR 2508; Etanidazolum; Etanidazol; N-(2-Hydroxyethyl)-2-nitro-1H-imidazole-1-acetamide; SR2508. Grade: 98%. CAS No. 22668-01-5. Molecular formula: C7H10N4O4. Mole weight: 214.18. | |
| Etaracizumab | Etaracizumab is a humanized monoclonal IgG1 antibody that targets alpha-v beta-3 integrin. Alpha-v beta-3 integrin plays an important role in tumor angiogenesis. Etaracizumab has the potential for the treatment of cancers. Synonyms: Abegrin; Vitaxin; LM-609; LM 609; LM609; MEDI-523; MEDI 523; MEDI523. CAS No. 892553-42-3. Molecular formula: C6392H9908N1732O1996S42. Mole weight: 144.3 kDa. | |
| Etarfolatide | A folate receptor-targeting radiopharmaceutical consisting of a folate-containing tetrapeptide chelator to which technetium Tc 99m is linked. The folate component of folate receptor-targeted technetium Tc99m-EC20 binds to folic acid receptors, which are frequently upregulated in many types of tumor cells and activated macrophages. An investigational drug in clinical trials for the treatment of breast neoplasms, non small cell lung cancer (NSCLC), and adenocarcinoma of the lung. CAS No. 479578-27-3. Molecular formula: C29H34N10O11S. Mole weight: 730.71. | |
| Etavopivat | Etavopivat is a selective and orally active erythrocyte pyruvate kinase (PKR) activator. Etavopivat has potent antisickling effects that can be used in studies of sickle cell disease and other haemoglobinopathies. Synonyms: FT-4202; FT4202; (S)-1-(5-((2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-7-yl)sulfonyl)-3,4,5,6-tetrahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)-3-hydroxy-2-phenylpropan-1-one. CAS No. 2245053-57-8. Molecular formula: C22H23N3O6S. Mole weight: 457.50. | |
| Etazolate hydrochloride | Etazolate hydrochloride is a phosphodiesterase inhibitor with selectivity for PDE4 (IC50 = 2.0 μM). Synonyms: 1-Ethyl-4-[(1-methylethylidene)hydrazino]-1H-pyrazolo-[3,4-b]-pyridine-5-carboxylic acid, ethyl ester hydrochloride; Etazolate HCl. Grade: ≥98% by HPLC. CAS No. 35838-58-5. Molecular formula: C14H19N5O2.HCl. Mole weight: 325.8. | |
| Etbicuphat | Etbicuphat is a GABAa receptor antagonist known to cause convulsions, seizures and other neuromuscular related episodes. Used in the study of anti-epileptic drugs. Synonyms: Ethyl bicyclic phosphate; TMP-P; Trimethylopropane phosphate; Trimethyolpropane phosphate; Etbicuphat; 2,6,7-Trioxa-1-phosphabicyclo[2.2.2]octane, 4-ethyl-, 1-oxide; 1,1,1-Trimethylolpropane Phosphate; 4-Ethyl-2,6,7-trioxa-1-phosphabicyclo[2.2.2]octane 1-oxide; 2-(Hydroxymethyl)-2-ethyl-1,3-propanediol, cyclic phosphate (1:1); 2-Ethyl-2-(hydroxymethyl)-1,3-propanediol, cyclic phosphate (1:1); 4-Ethyl-1-phospha-2,6,7-trioxabicyclo(2.2.2)octane-1-oxide; 1,3-Propanediol, 2-ethyl-2-(hydroxymethyl)-, cyclic phosphate; 4-ethyl-2,6,7-trioxa-1lambda5-phosphabicyclo[2.2.2]octane 1-oxide; 4-Aethyl-1-phospha-2,6,7-trioxabicyclo(2.2.2)octan-1-oxid; 4-Ethyl-2,6,7-trioxa-1-phosphabicyclo(2.2.2)octane-1-oxide. Grade: 95 % (NMR). CAS No. 1005-93-2. Molecular formula: C6H11O4P. Mole weight: 178.12. | |
| ETC-1002 | ETC-1002 is a novel, first-in-class, orally available, once-daily LDL-C lowering small molecule and is activator of hepatic AMP-activated protein kinase (AMPK). It also has potent inhibitory activity against hepatic ATP-citrate lyase. Synonyms: ESP-55016; ESP55016; ESP 55016; ETC-1002; ETC 1002; ETC1002; Bempedoate; Bempedoic acid. Grade: >98%. CAS No. 738606-46-7. Molecular formula: C19H36O5. Mole weight: 344.49. | |
| ETC-159 | ETC-159, also known as ETC-1922159, is a potent, selective and orally available PORCN inhibitor. ETC-159 blocks the secretion and activity of all Wnts. Synonyms: ETC-159; ETC159; ETC 159; ETC-1922159; ETC 1922159; ETC1922159. Grade: 98%. CAS No. 1638250-96-0. Molecular formula: C19H19N7O3. Mole weight: 393.41. | |
| ETC-206 | ETC-206 is a selective MNK1 and MNK2 inhibitor with IC50 of 64 nM and 86 nM, respectively. Synonyms: ETC206; ETC 206. Grade: 98%. CAS No. 1464151-33-4. Molecular formula: C25H20N4O2. Mole weight: 408.5. | |
| Etebenecid | Etebenecid, a benzenesulfonic acid derivative, could be used to reduce uric acid levels acting as a uricosuric agent. Uses: Etebenecid could be used to reduce uric acid levels acting as a uricosuric agent. Synonyms: Etebenecidum; Etebenecid; NSC 49467; NSC-49467; NSC49467 Ethebenecide; Urelim; N,N-DIETHYL-4-SULFAMOYLBENZOIC ACID; 4-((diethylamino)sulfonyl)-benzoicaci; p-(diethylsulfamoyl)-benzoicaci; p-(diethylsulfamoyl)benzoicacid; Antidipsin; Etebenecid. Grade: 95%. CAS No. 1213-06-5. Molecular formula: C11H15NO4S. Mole weight: 257.31. | |
| Etelcalcetide hydrochloride | Etelcalcetide is a calcium-sensing receptor agonist as a D-amino peptide calcimimetic for the treatment of secondary hyperparathyroidism. It can bind to and activate the CaSR (calcium-sensing receptor) in the parathyroid gland as an allosteric activator, resulting in PTH reduction and suppression. Amgen Inc. announced its submission of a New Drug Application to the FDA for etelcalcetide in Aug 2015. Synonyms: AMG-416; AMG 416; AMG416; Etelcalcetide hydrochloride; KAI-4169; KAI-4169-HCl; ONO-5163; Parsabiv; Telcalcetide; Velcalcetide; Velcalcetide hydrochloride; N-Acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-D-argininamide disulfide with L-cysteine hydrochloride; 1262780-97-1 (free). Grade: >98%. CAS No. 1334237-71-6. Molecular formula: C38H74ClN21O10S2. Mole weight: 1084.72. | |
| eteplirsen | Eteplirsen, a morpholino phosphorodiamidate antisense oligomer. Eteplirsen is a drug developed for the treatment of some mutations resulting in Duchenne muscular dystrophy (DMD). It has an effect of decreasing dystrophin levels from baseline in muscle tissues in the therapy. Eteplirsen has received orphan drug designation in the USA and EU, and rare paediatric disease designation in the USA used for DMD. Uses: The treatment of duchenne muscular dystrophy (dmd). Synonyms: Exondys 51; AVI-4658; AVI4658; AVI 4658. CAS No. 1173755-55-9. Molecular formula: C364H569N177O122P30. Mole weight: 10305.738. | |
| Etersalate | Etersalate is a compound that inhibits platelet function at lower dosages. Synonyms: Eterylate; Etherylate; Daital; 2-(Acetyloxy)benzoic acid 2-(4-(acetylamino)phenoxy)ethyl ester. CAS No. 62992-61-4. Molecular formula: C19H19NO6. Mole weight: 357.36. | |
| Etesevimab | Etesevimab is a human recombinant monoclonal antibody that targets the SARS-CoV-2 surface spike protein receptor-binding domain. Etesevimab has been authorized for emergency use by the FDA for the treatment of COVID-19. Synonyms: CB 6; JS016. CAS No. 2423948-94-9. Molecular formula: C9H13N3O5. Mole weight: 243.22. | |
| ETH 2120 | ETH 2120, also known as Sodium ionophore III, is an ionophore suitable for the assay of Na+-activity in blood, plasma, serum. etc. with a solvent polymeric membrane electrode. Synonyms: ETH-2120; ETH2120; N,N,N',N'-Tetracyclohexyl-1,2-phenylenedioxydiacetamide; Sodium ionophore III. CAS No. 81686-22-8. Molecular formula: C34H52N2O4. Mole weight: 552.8. | |
| Ethacizine hydrochloride | Ethacizine hydrochloride inhibits the depolarizing current responsible for the intraatrial and His-Purkinje-ventricular conduction. NIK-244 should be classified as a slow kinetic drug and as Ic. Synonyms: Ethacizine (hydrochloride). Grade: 98%. CAS No. 57530-40-2. Molecular formula: C22H28ClN3O3S. Mole weight: 449.99. | |
| Ethacridine | Ethacridine. Synonyms: 2-ETHOXY-6,9-DIAMINOACRIDINE; 6,9-DIAMINO-2-ETHOXYACRIDINE; 7-ETHOXY-ACRIDINE-3,9-DIAMINE; ACRINOL; RIVANOL; Ethacridine; Ethacrindine; 6,9-DIAMINO-2-ETHOXYACRIDINEHYDROCHLORIDE. CAS No. 442-16-0. Molecular formula: C15H15N3O. Mole weight: 253.303. | |
| Ethacridine lactate monohydrate | Ethacridine lactate monohydrate is an aromatic organic compound based on acridine used as an antiseptic agent. Uses: Anti-infective agents, local. Synonyms: AMN-107; AMN107; AMN107. Grade: >98%. CAS No. 6402-23-9. Molecular formula: C15H15N3O·C3H6O3·H2O. Mole weight: 361.39. | |
| Ethacrynic acid dimethylamino analog | Ethacrynic acid dimethylamino analog is an impurity of Ethacrynic acid, a diuretic used to treat chronic heart failure and high blood pressure. Synonyms: {2,3-Dichloro-4-[2-{(dimethylamino)methyl}butanoyl]phenoxy}acetic acid hydrochloride. CAS No. 1592-83-2. Molecular formula: C15H20Cl3NO4. Mole weight: 384.68. | |
| Ethacrynic acid Impurity E | Ethacrynic acid Impurity E is an impurity of Ethacrynic acid, a diuretic used to treat chronic heart failure and high blood pressure. Synonyms: [2,3-dichloro-4-(2-methylene-1-oxopropyl)phenoxy]acetic acid. CAS No. 55507-91-0. Molecular formula: C12H10Cl2O4. Mole weight: 289.11. | |
| Ethacrynic acid Impurity G | Ethacrynic acid Impurity G is an impurity of Ethacrynic acid, a diuretic used to treat chronic heart failure and high blood pressure. CAS No. 55507-81-8. Molecular formula: C14H14Cl2O4. Mole weight: 317.16. | |
| Ethacrynic Acid L-Cysteine Adduct | Ethacrynic Acid L-Cysteine Adduct is a metabolite of Ethacrynic Acid, which is a loop diuretic used to treat high blood pressure and the swelling caused by diseases like congestive heart failure and kidney failure. Synonyms: S-[2-[4-(Carboxymethoxy)-2,3-dichlorobenzoyl]butyl]-L-cysteine, Cysteine-ethacrynic Acid; Cysteine-ethacrynic Acid Adduct; Ethacrynic Acid-cysteine Complex. Grade: 97%. CAS No. 51246-37-8. Molecular formula: C16H19Cl2NO6S. Mole weight: 424.30. | |
| Ethacrynic Acid Mercapturate | Ethacrynic Acid Mercapturate is a metabolite of Ethacrynic Acid, which is a loop diuretic used to treat high blood pressure and the swelling caused by diseases like congestive heart failure and kidney failure. Synonyms: N-Acetyl-S-[2-[4-(carboxymethoxy)-2,3-dichlorobenzoyl]butyl]-L-cysteine; L-Cysteine, N-acetyl-S-[2-[4-(carboxymethoxy)-2,3-dichlorobenzoyl]butyl]-. Grade: 98%. CAS No. 54546-23-5. Molecular formula: C18H21Cl2NO7S. Mole weight: 466.33. | |
| Ethacrynic acid pyrane dimer | Ethacrynic acid pyrane dimer is an impurity of Ethacrynic acid, a diuretic used to treat chronic heart failure and high blood pressure. Synonyms: 2-(4-(2-(4-(Carboxymethoxy)-2,3-dichlorobenzoyl)-2,5-diethyl-3,4-dihydro-2H-pyran-6-yl)-2,3-dichlorophenoxy)acetic Acid; Ethacrynic acid dimer. CAS No. 25355-92-4. Molecular formula: C26H24Cl4O8. Mole weight: 606.27. | |
| Ethacrynic acid Related Compound A | Ethacrynic acid Related Compound A is an impurity of Ethacrynic acid, a diuretic used to treat chronic heart failure and high blood pressure. Synonyms: Acetic acid, (2,3-dichloro-4-(1-oxobutyl)phenoxy)-; 4-Butyryl-2,3-dichlorophenoxyacetic acid. CAS No. 1217-67-0. Molecular formula: C12H12Cl2O4. Mole weight: 291.12. | |
| Ethacrynic acid trichloro analog | Ethacrynic acid trichloro analog is an impurity of Ethacrynic acid, a diuretic used to treat chronic heart failure and high blood pressure. Synonyms: 2-Desmethylene-2-chloromethyl Ethacrynic Acid. CAS No. 27929-18-6. Molecular formula: C13H13Cl3O4. Mole weight: 339.60. | |
| Ethambutol R,R-Isomer DiHCl | An isomer of Ethambutol. Ethambutol is a medication primarily used to treat tuberculosis. Synonyms: (R,R)-Ethambutol Dihydrochloride. Grade: > 95%. CAS No. 134566-79-3. Molecular formula: C10H24N2O2. 2 HCl. Mole weight: 277.23. | |
| Ethanol, 2-(2-ethoxyphenoxy)-, methanesulfonate | One of the impurities of Tamsulosin, which is an α1-adrenoceptor antagonist and could be used against benign prostatic hypertrophy. Synonyms: 2-(2-ethyloxyphenoxy)ethyl methanesulfonate. CAS No. 169506-15-4. Molecular formula: C11H16O5S. Mole weight: 260.31. | |
| Ethaselen | Ethaselen, also known as BBSKE, is a novel organoselenium thioredoxin reductase inhibitor, is currently being investigated in a phase I clinical trial in China. Ethaselen enhanced the efficacy of radiation therapy both in vivo and in vitro without observable toxicity. BBSKE was found to suppress irradiation-induced activation dramatically when using A549 cells stably transfected with luciferase reporter. Ethaselen is a potentially promising agent for the treatment of patients with NSCLC clinically. Synonyms: 1,2-[bis(1,2-benzisoselenazolone-3(2H)-ketone)]ethane; BBSKE. CAS No. 217798-39-5. Molecular formula: C16H12N2O2Se2. Mole weight: 422.199. | |
| Etheno-2'-deoxyadenosine | Etheno-2'-deoxyadenosine is an etheno DNA-adduct of adenosine found in atherosclerotic lesions and a biomarker for genotoxicity. Synonyms: Ethenodeoxyadenosine; 68498-25-9; N6-Etheno 2'-deoxyadenosine; etheno-2'-deoxyadenosine; 1,N6-Ethenodeoxyadenosine; 3H-Imidazo[2,1-i]purine, 3-(2-deoxy-b-D-erythro-pentofuranosyl)-; 1,N(6)-Ethenodeoxyadenosine; 1,N6-Etheno-2'-deoxyadenosine; Etheno-2'-deoxy-beta-D-adenosine; etheno-dA; 1,N6-Etheno-dA; BIDD:GT0712; 3-(2-Deoxy-beta-D-erythro-pentofuranosyl)-3H-imidazo[2,1-i]purine; 1,N6-etheno-2 -deoxyadenosine; SCHEMBL19666769; N1,N6-Etheno-2'-deoxyadenosine; CHEBI:165837; XQQIMTUYVDUWKJ-DJLDLDEBSA-N; DTXSID501031841; MFCD00056769; AKOS040744309; CS-W010084; MS-23909; HY-111646; (2R,3S,5R)-2-(hydroxymethyl)-5-imidazo[2,1-]purin-3-yloxolan-3-ol; (2R,3S,5R)-2-(hydroxymethyl)-5-imidazo[2,1-f]purin-3-yloxolan-3-ol; (2R,3S,5R)-2-(hydroxymethyl)-5-(3H-imidazo[1,2-i]purin-3-yl)tetrahydrofuran-3-ol; (2R,3S,5R)-2-(hydroxymethyl)-5-{3H-imidazo[2,1-f]purin-3-yl}oxolan-3-ol. Grade: ≥ 98% by HPLC. Molecular formula: C12H13N5O3. Mole weight: 275.26. | |
| Etheno-2'-deoxycytidine | Etheno-2'-deoxycytidine, a nucleoside analog, is a powerful investigative tool in the field of cancer research for studying the multifarious impacts of DNA damage and repair. This versatile compound engenders DNA adducts that can induce apoptosis and even impede the cell cycle in cancer cells. Its therapeutic potential is not limited to just the treatment of cancer but to other conditions that involve DNA damage and repair as well. Grade: ≥ 98% by HPLC. Molecular formula: C11H13N3O4. Mole weight: 251.24. | |
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