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| Product | Description | |
|---|---|---|
| Erlose | Erlose is a widely utilized pharmaceutical in the biomedical sector, serving as a prominent role for studying Type 2 diabetes. Its mechanism of action entails augmenting glycemic regulation while concurrently amplifying the responsiveness of cells towards insulin. Synonyms: a-D-Glc-(1→4)-a-D-Glc-(1→2)-b-D-Fru; a-Maltosyl b-fructofuranoside; β-D-Fructofuranosyl O-α-D-glucopyranosyl-(1→4)-α-D-glucopyranoside; Fructomaltose. CAS No. 13101-54-7. Molecular formula: C18H32O16. Mole weight: 504.44. |  |
| Erlosiban | Erlosiban, an iminopyrrolidin derivative, has been found to be a nonpeptide oxytocin receptor antagonist that could probably be used in the treatment of female infertility and preterm labour. It is still under Phase II clinical trail in Preterm labour. Synonyms: UOBE-001; OBE001; OBE001; NII-3765U8A1EC; CHEMBL1254025; 3765U8A1EC; Erlosiban; Erlosiban [INN]; [(2S,4Z)-2-(hydroxymethyl)-4-methoxyiminopyrrolidin-1-yl]-[4-(2-methylphenyl)phenyl]methanone. Grade: 98%. CAS No. 1477482-19-1. Molecular formula: C20H22N2O3. Mole weight: 338.41. | |
| Erlotinib-3-vinyl Hydrochloride | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6,7-Bis(2-methoxyethoxy)-N-(3-vinylphenyl)quinazolin-4-amine hydrochloride; 4-Quinazolinamine, N-(3-ethenylphenyl)-6,7-bis(2-methoxyethoxy)-, hydrochloride (1:1). Grade: 95%. CAS No. 1624294-38-7. Molecular formula: C22H26ClN3O4. Mole weight: 431.91. | |
| Erlotinib Carboxylic Acid | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Erlotinib Metabolite M6; Erlotinib Acid. Grade: > 95%. Molecular formula: C22H25N3O6. Mole weight: 427.46. | |
| Erlotinib Hydroxy Metabolite | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Hydroxy Erlotinib; N-(3-Ethynyl-4-hydroxy-phenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl] amine hydrochloride. Grade: > 95%. CAS No. 882420-22-6. Molecular formula: C22H23N3O5. Mole weight: 409.45. | |
| Erlotinib impurity 1 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-(3-(1-chlorovinyl)phenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine. Grade: > 95%. Molecular formula: C22H24ClN3O4. Mole weight: 429.91. | |
| Erlotinib Impurity 11 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N'-[2-Cyano-4,5-bis(2-methoxyethoxy)phenyl]-N,N-dimethylimidoformamide. Grade: > 95%. CAS No. 950596-59-5. Molecular formula: C16H23N3O4. Mole weight: 321.38. | |
| Erlotinib Impurity 12 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: (E)-2-(((dimethylamino)methylene)amino)-4,5-bis(2-methoxyethoxy)benzamide. Grade: > 95%. Molecular formula: C16H25N3O5. Mole weight: 339.39. | |
| Erlotinib Impurity 13 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4,5-bis(2-methoxyethoxy)-2-nitrobenzonitrile. Grade: > 95%. CAS No. 236750-65-5. Molecular formula: C13H16N2O6. Mole weight: 296.28. | |
| Erlotinib Impurity 14 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-Amino-4,5-bis(2-methoxyethoxy)benzamide. Grade: > 95%. CAS No. 236750-62-2. Molecular formula: C13H20N2O5. Mole weight: 284.31. | |
| Erlotinib Impurity 15 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: ethyl 2-amino-3,4-bis(2-methoxyethoxy)benzoate. Grade: > 95%. Molecular formula: C15H23NO6. Mole weight: 313.35. | |
| Erlotinib Impurity 16 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 3-((7,8-bis(2-methoxyethoxy)quinazolin-4-yl)amino)benzonitrile. Grade: > 95%. Molecular formula: C22H23N3O6. Mole weight: 393.45. | |
| Erlotinib impurity 2 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4-Chloro-6-(2-Chloroethoxy)-7-(2-Methoxyethoxy)-Quinazoline. Grade: > 95%. CAS No. 183322-19-2. Molecular formula: C13H14Cl2N2O3. Mole weight: 317.17. | |
| Erlotinib Impurity 2 (4-Chloro-7-(2-Chloroethoxy)-6-(2-Methoxyethoxy)-Quinazoline) | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4-chloro-7-(2-chloroethoxy)-6-(2-methoxyethoxy)quinazoline. Grade: > 95%. CAS No. 183322-20-5. Molecular formula: C13H14Cl2N2O3. Mole weight: 317.17. | |
| Erlotinib impurity 3 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2,4-dichloro-6,7-bis(2-methoxyethoxy)quinazoline. Grade: > 95%. Molecular formula: C14H16Cl2N2O4. Mole weight: 347.20. | |
| Erlotinib impurity 4 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 3-((6,7-bis(2-methoxyethoxy)quinazolin-4-yl)amino)benzoic acid. Grade: > 95%. Molecular formula: C21H23N3O6. Mole weight: 413.43. | |
| Erlotinib Impurity 5 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6,7-bis(2-methoxyethoxy)-N-phenylquinazolin-4-amine. Grade: > 95%. Molecular formula: C20H25N3O4. Mole weight: 369.42. | |
| Erlotinib impurity, 6-(2-chloroethoxy)-7-(2-methoxyethoxy) | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 7-(2-chloroethoxy)-N-(3-ethynylphenyl)-6-(2-methoxyethoxy)-4-Quinazolinamine. Grade: > 95%. CAS No. 183321-85-9. Molecular formula: C21H20ClN3O3. Mole weight: 397.86. | |
| Erlotinib impurity, 6-(2-methoxyethoxy)-7-(2-chloroethoxy) | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6-(2-chloroethoxy)-N-(3-ethynylphenyl)-7-(2-methoxyethoxy)quinazolin-4-amine. Grade: > 95%. CAS No. 183321-83-7. Molecular formula: C21H20ClN3O3. Mole weight: 397.86. | |
| Erlotinib impurity, 6,7-bis(2-chloroethoxy) | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6,7-bis(2-chloroethoxy)-N-(3-ethynylphenyl)quinazolin-4-amine. Grade: > 95%. CAS No. 183321-82-6. Molecular formula: C20H17Cl2N3O2. Mole weight: 402.28. | |
| Erlotinib Impurity 7 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-amino-4,5-bis(2-methoxyethoxy)benzoic acid ethyl ester hydrochloride. Grade: > 95%. CAS No. 183322-17-0. Molecular formula: C15H23NO6 HCl. Mole weight: 349.81. | |
| Erlotinib Impurity 8 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-(3-Desethynylphenyl)-N-(3-bromophenyl) Erlotinib; N-(3-bromophenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine. Grade: > 95%. CAS No. 328528-74-1. Molecular formula: C20H22BrN3O4. Mole weight: 448.32. | |
| Erlotinib Impurity 9 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-(6,7-bis(2-methoxyethoxy)quinazolin-4-yl)-N-(3-cyanophenyl)acetamide. Grade: > 95%. Molecular formula: C24H25N3O5. Mole weight: 435.48. | |
| Erlotinib mesylate | Erlotinib is an EGFR inhibitor. The drug follows Iressa (gefitinib), which was the first drug of this type. Erlotinib specifically targets the epidermal growth factor receptor (EGFR) tyrosine kinase, which is highly expressed and occasionally mutated in various forms of cancer. It binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. For the signal to be transmitted, two EGFR molecules need to come together to form a homodimer. These then use the molecule of ATP to trans-phosphorylate each other on tyrosine residues, which generates phosphotyrosine residues, recruiting the phosphotyrosine-binding proteins to EGFR to assemble protein complexes that transduce signal cascades to the nucleus or activate other cellular biochemical processes. By inhibiting the ATP, formation of phosphotyrosine residues in EGFR is not possible and the signal cascades are not initiated. Synonyms: Tarceva; CP-358774; CP 358774; CP358774; OSI-774; OSI 774; OSI774; NSC 718781; NSC718781; NSC-718781; R 1415; R1415; R-1415. Grade: >98%. CAS No. 248594-19-6. Molecular formula: C23H27N3O7S. Mole weight: 489.54. | |
| Erlotinib metabolite M11 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl]oxy]acetic Acid. Grade: > 95%. CAS No. 882172-60-3. Molecular formula: C21H19N3O5. Mole weight: 393.40. | |
| Erlotinib metabolite M12 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-hydroxyethoxy)quinazoline; 2-(4-(3-Ethynylanilino)-7-(2-hydroxyethoxy)quinazolin-6-yl)oxyethanol; 2-[4-(3-ethynylanilino)-7-(2-hydroxyethoxy)quinazolin-6-yl]oxyethanol. CAS No. 183321-84-8. Molecular formula: C20H19N3O4. Mole weight: 365.389. | |
| Erlotinib O-Desmethyl Metabolite Isomer | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Erlotinib 7-O-Desmethyl Metabolite; 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl] oxy]ethanol. Grade: > 95%. CAS No. 183320-29-8. Molecular formula: C21H21N3O4. Mole weight: 379.42. | |
| Erlotinib O-Desmethyl Metabolite Isomer (M14) HCl | OSI-420 (CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells. Uses: For research used only. Synonyms: OSI420; OSI-420; OSI 420; CP473420; CP-473420; CP 473420; Desmethyl Erlotinib. Grade: > 95%. CAS No. 183320-51-6. Molecular formula: C21H22ClN3O4. Mole weight: 415.874. | |
| ERRα antagonist-1 | ERRα antagonist-1, a selective and high affinity antagonist of estrogen-related receptor α (ERRα), inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β with IC50s of 170 and 180 nM, respectively. It does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1. Synonyms: N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine; ERRa antagonist-1; 5H-Dibenzo[a,d]cyclohepten-5-amine, N-[3-(4,5-dihydro-2-thiazolyl)-2-thiazolidinylidene]-. Grade: ≥95%. CAS No. 1072145-33-5. Molecular formula: C21H19N3S2. Mole weight: 377.53. | |
| ERRγ Inverse Agonist 1 | ERRγ Inverse Agonist 1 is a potent, selective and orally bioavailable inverse agonist of Estrogen-related Receptor grammar (ERRγ), with an IC50 of 40 nM. Synonyms: Benzenebutanol, δ-[(3-hydroxyphenyl)[4-[4-(1-methylethyl)-1-piperazinyl]phenyl]methylene]-, hydrochloride (1:2), (δE)-; 3-{(1E)-5-Hydroxy-1-[4-(4-isopropyl-1-piperazinyl)phenyl]-2-phenyl-1-penten-1-yl}phenol dihydrochloride. CAS No. 2316832-86-5. Molecular formula: C30H38Cl2N2O2. Mole weight: 529.54. | |
| Ertapenem Acetic Acid Adduct Impurity | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: (4R,5S)-1-acetyl-5-((1S,2R)-1-carboxy-2-hydroxypropyl)-3-(((3R,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-yl)thio)-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid. Grade: > 95%. Molecular formula: C24H27N3O9S. Mole weight: 533.56. | |
| Ertapenem Dimer Amide Impurity | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: Ertapenem Dimer III; (4R,5S,6S)-3-[[(3S,5S)-5-[[[3-[[(2S,3R)-5-Carboxy-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-[[(3S,5S)-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-2,3-dihydro-3-methyl-1H-pyrrol-1-yl]carbonyl]phenyl]amino]carbonyl]-3-pyrr. Grade: > 95%. CAS No. 1199797-42-6. Molecular formula: C44H50N6O14S2. Mole weight: 951.05. | |
| Ertapenem Dimer H2Oa | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: (4R,5S,6S)-3-[[(3S,5S)-5-[[[3-[[(1R,2S)-2-Carboxy-2-[(2S,3R)-5-carboxy-4-[[(3S,5S)-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-3,4-dihydro-3-methyl-2H-pyrrol-2-yl]-1-methylethoxy]carbonyl]phenyl]amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1. Grade: > 95%. Molecular formula: C44H48N6O14S2. Mole weight: 933.03. | |
| Ertapenem Dimer I | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: (4R,5S,6S)-3-[[(3S,5S)-1-[(2S,3R)-2-[(2S,3R)-5-Carboxy-4-[[(3S,5S)-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-3,4-dihydro-3-methyl-2H-pyrrol-2-yl]-3-hydroxy-1-oxobutyl]-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hyd. Grade: > 95%. CAS No. 1199797-41-5. Molecular formula: C44H50N6O14S2. Mole weight: 951.05. | |
| Ertapenem Dimer II | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: Ertapenem Dimer Ester Impurity; (4R,5S,6S)-3-[[(3S,5S)-5-[[[3-[[(1R,2S)-2-Carboxy-2-[(2S,3R)-5-carboxy-4-[[(3S,5S)-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-3,4-dihydro-3-methyl-2H-pyrrol-2-yl]-1-methylethoxy]carbonyl]phenyl]amino]carbonyl. Grade: > 95%. CAS No. 402955-38-8. Molecular formula: C44H50N6O14S2. Mole weight: 951.05. | |
| Ertapenem Impurity DIPP | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: 3-((2S,4S)-1-(diisopropoxyphosphoryl)-4-mercaptopyrrolidine-2-carboxamido)benzoic acid. Grade: > 95%. CAS No. 220031-86-7. Molecular formula: C18H27N2O6PS. Mole weight: 430.46. | |
| Ertapenem Impurity Pro-maba | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: (S)-3-(pyrrolidine-2-carboxamido)benzoic acid. Grade: > 95%. CAS No. 724700-26-9. Molecular formula: C12H14N2O3. Mole weight: 234.26. | |
| Ertapenem Methanolysis Impurity | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: (2S,3R)-4-(((3R,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-yl)thio)-2-((2R,3S)-2-hydroxy-4-oxopentan-3-yl)-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid. Grade: > 95%. Molecular formula: C23H27N3O7S. Mole weight: 489.55. | |
| Ertapenem N-Carbonyl Dimer Impurity | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: (4R,5S,6S)-3-[[(3S,5S)-1-[3-[[[(2S,4S)-4-[[(4R,5S,6S)-2-Carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-2-pyrrolidinyl]carbonyl]amino]benzoyl]-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydro. Grade: > 95%. CAS No. 1199797-43-7. Molecular formula: C44H48N6O13S2. Mole weight: 933.03. | |
| Ertapenem Oxazinone Impurity | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: (3S,4S,4aS,5R)-4-acetyl-6-(((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-yl)thio)-3,5-dimethyl-1-oxo-3,4,4a,5-tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazine-7-carboxylic acid. Grade: > 95%. Molecular formula: C23H25N3O9S. Mole weight: 519.53. | |
| Ertapenem Ring Open Impurity | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: 1H-Pyrrole-2-acetic acid, 5-carboxy-4-[[(3S,?5S)?-5-[[(3-carboxyphenyl)?amino]?carbonyl]?-3-pyrrolidinyl]?thio]?-2,?3-dihydro-α-[(1R)?-1-hydroxyethyl]?-3-methyl-, (αS,?2S,?3R)?-. Grade: > 95%. CAS No. 357154-27-9. Molecular formula: C22H27N3O8S. Mole weight: 493.54. | |
| Ertapenem Side Chain Enantiomer 1 | An intermediate of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: 3-[[[(2S,4S)-1-(4-Nitrobenzyloxycarbonyl)-4-mercaptopyrrolidin-2-yl]carbonyl]amino]benzoic Acid; (2S-cis)-2-[[(3-Carboxyphenyl)amino]carbonyl]-4-mercapto-1-pyrrolidinecarboxylic Acid 1-[(4-Nitrophenyl)methyl] Ester. Grade: > 95%. CAS No. 202467-69-4. Molecular formula: C20H19N3O7S. Mole weight: 445.45. | |
| Ertapenem Side Chain Enantiomer 2 HCl | An intermediate of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: 3-((2S,4S)-4-mercaptopyrrolidine-2-carboxamido)benzoic acid HCl. Grade: > 95%. CAS No. 503607-49-6. Molecular formula: C12H14N2O3S. HCl. Mole weight: 266.32 36.46. | |
| Ertapenem side chain impurity (propyl ester) | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: propyl 3-((2S,4S)-4-mercaptopyrrolidine-2-carboxamido)benzoate. Grade: > 95%. Molecular formula: C15H20N2O3S. Mole weight: 308.40. | |
| Erteberel | Erteberel is a potent, selective estrogen receptor β agonist with EC50 of 0.66 nM, 32-fold selectivity against estrogen receptor α. Synonyms: LY500307; (3aS,4R,9bR)-1,2,3,3a,4,9b-Hexahydro-4-(4-hydroxyphenyl)cyclopenta[c][1]benzopyran-8-ol; (2R,6S,7R)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0.02,6]trideca-1(13),9,11-trien-12-ol; Benzo[b]cyclopenta[d]pyran-8-ol, 1,2,3,3a,4,9b-hexahydro-4-(4-hydroxyphenyl)-, (3aS,4R,9bR)-. Grade: >98%. CAS No. 533884-09-2. Molecular formula: C18H18O3. Mole weight: 282.33. | |
| Ertiprotafib | Ertiprotafib is an inhibitor of protein tyrosine phosphatase 1B (PTP1B), IkB kinase β (IKK-β), and a dual agonist of PPARα and PPARβ, with IC50s of 1.6 μM and 400 nM for PTP1B and IKK-β, and EC50s of ~1 μM for PPARα/PPARβ. It is potentially useful for the treatment of non-insulin dependent diabetes. Synonyms: PTP 112; Benzenepropanoic acid, α-[4-(9-bromo-2,3-dimethylnaphtho[2,3-b]thien-4-yl)-2,6-dimethylphenoxy]-, (αR)-; (2R)-2-(4-(9-Bromo-2,3-dimethylnaphtho(2,3-b)thiophen-4-yl)-2,6-dimethylphenoxy)-3-phenylpropionic acid; (αR)-α-[4-(9-Bromo-2,3-dimethylnaphtho[2,3-b]thien-4-yl)-2,6-dimethylphenoxy]benzenepropanoic Acid. Grade: 98%. CAS No. 251303-04-5. Molecular formula: C31H27BrO3S. Mole weight: 559.52. | |
| Ertugliflozin | PF-04971729, a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2, is developed for the treatment of diabetes mellitus. Inhibitory effects against the organic cation transporter 2-mediated uptake of [14C]metformin by PF-04971729 is very weak (IC50 = 900μM). Uses: Sodium-glucose transporter 2 inhibitors. Synonyms: PF-04971729; PF 04971729; PF04971729; PF-04971729-00; 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranose; MK 8835; Steglatro; β-L-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-; 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranose; (1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol. Grade: >98%. CAS No. 1210344-57-2. Molecular formula: C22H25ClO7. Mole weight: 436.88. | |
| Ertugliflozin 2-O-β-D-glucuronide | Ertugliflozin 2-O-β-D-glucuronide is an impurity of Ertugliflozin, which is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 and is developed for the treatment of diabetes mellitus. Synonyms: 2-O-beta-D-Glucopyranuronosyl Ertugliflozin; 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-2-O-β-D-glucopyranuronosyl-5-C-(hydroxymethyl)-β-L-idopyranose. CAS No. 1500090-84-5. Molecular formula: C28H33ClO13. Mole weight: 613.01. | |
| Ertugliflozin 3-O-β-D-glucuronide | Ertugliflozin 3-O-β-D-glucuronide is an impurity of Ertugliflozin, which is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 and is developed for the treatment of diabetes mellitus. Synonyms: Ertugliflozin metabolite M5c; 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-3-O-β-D-glucopyranuronosyl-5-C-(hydroxymethyl)-β-L-idopyranose. CAS No. 1500090-85-6. Molecular formula: C28H33ClO13. Mole weight: 613.01. | |
| Ertugliflozin intermediate | Ertugliflozin intermediate is an intermediate of Ertugliflozin, which is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 and is developed for the treatment of diabetes mellitus. Synonyms: ((1S,2S,3S,4R,5S)-2,3,4-tris(Benzyloxy)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6,8-dioxabicyclo[3.2.1]octan-1-yl)methanol; β-L-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-2,3,4-tris-O-(phenylmethyl)-; 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-2,3,4-tris-O-(phenylmethyl)-β-L-idopyranose. Grade: ≥95%. CAS No. 1638851-97-4. Molecular formula: C43H43ClO7. Mole weight: 707.25. | |
| Ertugliflozin L-pyroglutamic acid | Ertugliflozin L-pyroglutamic acid is an orally available inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2). Synonyms: MK-8835 L-pyroglutamic acid; PF-04971729 L-pyroglutamic acid. CAS No. 1210344-83-4. Molecular formula: C27H32ClNO10. Mole weight: 566. | |
| Erucin | Erucin is an isothiocyanate derived from glucoerucin, a glucosinolate predominant in arugula (Eruca sativa Mill.) and other cruciferous vegetables. Erucin exhibits antioxidant and antiproliferative effects in cancer cell lines, and induces cell apoptosis. Synonyms: 4-methylthiobutyl isothiocyanate; 4-(Methylthio)butyl isothiocyanate; 1-isothiocyanato-4-methylsulfanylbutane. CAS No. 4430-36-8. Molecular formula: C6H11NS2. Mole weight: 161.281. | |
| Ervogastat | Ervogastat is a potent diacylglycerol acyltransferase 2 (DGAT2) inhibitor. In combination with Clesacostat, Ervogastat is a promising therapy for the treatment of non-alcoholic steatohepatitis (NASH) with liver fibrosis. Synonyms: PF-06865571; PF 06865571; PF06865571. CAS No. 2186700-33-2. Molecular formula: C21H21N5O4. Mole weight: 407.42. | |
| Erythritol -d3 | Isotope labelled Erythritol. Erythritol a sugar alcohol used as a food additive. Synonyms: (2R,3S)-butane-1,2,3,4-tetraol-d3. Grade: > 95%. Molecular formula: C4H7O4D3. Mole weight: 125.14. | |
| Erythro-β,3-dihydroxy-DL-tyrosine | Erythro-β,3-dihydroxy-DL-tyrosine is an impurity of Droxidopa, which is a synthetic amino acid precursor used as a prodrug to the neurotransmitter norepinephrine (noradrenaline). Synonyms: Droxidopa Impurity 11 (DL-erythro-Droxidopa); DL-erythro-3,4-Dihydroxyphenylserine; Erythro-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropionic Acid; Erythro-3-(3,4-Dihydroxyphenyl)serine; rel-(βR)-β,3-Dihydroxy-D-tyrosine; DL-Tyrosine, β,3-dihydroxy-, erythro-; Serine, 3-(3,4-dihydroxyphenyl)-, DL-erythro-; D-Tyrosine, β,3-dihydroxy-, (βR)-rel-. CAS No. 16322-99-9. Molecular formula: C9H11NO5. Mole weight: 213.19. | |
| erythro-Glycopyrronium bromide | erythro-Glycopyrronium bromide is a prominent pharmaceutical compound acting as a potent anticholinergic agent. Its utmost significance lies in its unparalleled efficacy in studying chronic obstructive pulmonary disease (COPD) and asthma. Uses: Adjuvants, anesthesia. Synonyms: Pyrrolidinium, 3-[[(2R)-2-cyclopentyl-2-hydroxy-2-phenylacetyl]oxy]-1,1-dimethyl-, bromide (1:1), (3S)-rel-; Pyrrolidinium, 3-[(cyclopentylhydroxyphenylacetyl)oxy]-1,1-dimethyl-, bromide, (R*,S*)-(±)-; Pyrrolidinium, 3-[[(2R)-cyclopentylhydroxyphenylacetyl]oxy]-1,1-dimethyl-, bromide, (3S)-rel-; Ritropirronium bromide; erythro-3-Hydroxy-1,1-dimethylpyrrolidinium bromide α-cyclopentylmandelate. Grade: 98%. CAS No. 51186-83-5. Molecular formula: C19H28BrNO3. Mole weight: 398.33. | |
| Erythromycin, 2'-(ethyl carbonate) | Erythromycin, 2'-(ethyl carbonate) is a derivative of Erythromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: Erythromycin ethyl carbonatee; 2''-O-Ethoxycarbonylerythromycin; Erythromycin 2''-carbonic acid ethyl ester; (2S,3R,4S,6R)-4-(dimethylamino)-2-(((3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl)oxy)-6-methyltetrahydro-2H-pyran-3-yl ethyl carbonate. Grade: ≥95%. CAS No. 7218-80-6. Molecular formula: C40H71NO15. Mole weight: 806.00. | |
| Erythromycin, 2-hydroxypropanoate (salt) | Erythromycin, 2-hydroxypropanoate (salt) is the salt form of Erythromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: Erythromycin Forte; Erythromycin Lactate; 2-Hydroxypropanoic acid (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (1:1); Propanoic acid, 2-hydroxy-, compd. with erythromycin (1:1); Erythromycin, (±)-2-hydroxypropanoate; Erythromycin, 2-hydroxypropanoate (1:1). CAS No. 41033-54-9. Molecular formula: C37H67NO13.C3H6O3. Mole weight: 824.00. | |
| Erythromycin, 8,9-didehydro-9-deoxo-6-deoxy-6,9-epoxy-, (9S)- | An impurity of Erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 62S ribosomal subunit, blocking the progression of nascent polypeptide chains. Grade: > 95%. CAS No. 857839-61-3. Molecular formula: C37H65NO12. Mole weight: 715.91. | |
| Erythromycin A 6,9-Imino Ether | An impurity of Erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 52S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: [3R-(3R*,4R*,5S*,6R*,9R*,10S*,11S*,12R*,13R*,15R*)]-10-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-6-ethyl-4,5-dihydroxy-3,5,9,11,13,15-hexamethyl-12-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-16-Dioxa-2-azabicyclo[. Grade: > 95%. CAS No. 99290-97-8. Molecular formula: C37H66N2O12. Mole weight: 730.94. | |
| Erythromycin Acistrate | Erythromycin Acistrate is the salt form of Erythromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: (2S,3R,4S,6R)-4-(dimethylamino)-2-(((3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl)oxy)-6-methyltetrahydro-2H-pyran-3-yl acetate stearate (1:1); 2'-Acetyl erythromycin stearate salt; Erythromycin 2'-acetate, stearate (salt); Erythromycin, 2'-acetate, octadecanoate (salt); Octadecanoic acid, compd. with erythromycin 2'-acetate (1:1); 2'-Acetylerythromycin stearate; Erasis. Grade: 95%. CAS No. 96128-89-1. Molecular formula: C57H105NO16. Mole weight: 1060.46. | |
| Erythromycin A iminoether | An impurity of Azithromycin. Azithromycin, derived from erythromycin, is an antibiotic. It binds to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA. It is an azalide, a subclass of macrolide antibiotics and is one of the world's best-selling antibiotics. Synonyms: Erythromycin A 9,11-Imino Ether. Grade: > 95%. CAS No. 161193-44-8. Molecular formula: C37H66N2O12. Mole weight: 730.94. | |
| Erythromycin Carbonate | Erythromycin Carbonate is the salt form of Erythromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: Erythromycin, carbonate (ester); (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione carbonic acid (1:x). CAS No. 54579-17-8. Molecular formula: C37H67NO13.xCH2O3. Mole weight: 733.92 (free base). | |
| Erythromycin EP Impurity A | An impurity of Erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 58S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: Erythromycin F; 16-Hydroxyerythromycin; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3-(hydroxymethyl)-5,7,9,11,13-pentamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione. Grade: 95%. CAS No. 82230-93-1. Molecular formula: C37H67NO14. Mole weight: 749.93. | |
| Erythromycin EP Impurity C | An impurity of Erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 61S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: 1'',16-epoxy-Erythromycin; erythromycin E. Grade: 95%. CAS No. 41451-91-6. Molecular formula: C37H65NO14. Mole weight: 747.91. | |
| Erythromycin EP Impurity E | A decomposition product of the macrolide antibiotic, erythromycin A. Synonyms: 8,9-anhydroerythromycin A 6,9-hemiketal; Erythromycin A enol ether. Grade: >98% by HPLC. CAS No. 33396-29-1. Molecular formula: C37H65NO12. Mole weight: 715.91. | |
| Erythromycin EP Impurity F | A degradation product of erythromycin formed by a complex internal rearrangement of erythromycin A on exposure to neutral to weakly alkaline conditions. It is devoid of antibacterial activity but is an important analytical standard for erythromycin A stability studies. Synonyms: (2R,3R,6R,7S,8S,9R,10R)-7-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-3-[(1R,2R)-1,2-dihydroxy-1-methylbutyl]-2,6,8,10,12-pentamethyl-9-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-4,13-dioxabicyclo[8.2.1]tridec-12-en-5-one; 8,9-Anhydropseudo-erythromycin A-6,9-hemiketal; EM 701; LY 267108; Pseudo Erythromycin A enol ether; Pseudoerythromycin A enol ether. Grade: >98% by HPLC. CAS No. 105882-69-7. Molecular formula: C37H65NO12. Mole weight: 715.91. | |
| Erythromycin EP Impurity H | It is a minor analogue of the erythromycin complex isolated from saccharopolyspora erythraea. It is a facile metabolite formed in vivo which can revert to erythromycin A under reducing conditions. Synonyms: Erythromycin A N-oxide; Erythromycin N-oxide; erythromycin A 3''-N-oxide. Grade: >98% by HPLC. CAS No. 992-65-4. Molecular formula: C37H67NO14. Mole weight: 749.93. | |
| Erythromycin EP Impurity I | An impurity of Erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 61S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: Erythralosamine. CAS No. 546-57-6. Molecular formula: C29H49NO8. Mole weight: 539.70. | |
| Erythromycin EP Impurity J | An impurity of Erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 61S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: Pseudoerythromycin A hemiketal. CAS No. 105900-46-7. Molecular formula: C37H67NO13. Mole weight: 733.93. | |
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