BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Enzalutamide Impurity 2 | An impurity of Enzalutamide. Enzalutamide is an androgen-receptor (AR) antagonist in LNCaP cells. Synonyms: 3-Fluoro-4-methylphenylisothiocyanate. Grade: > 95%. CAS No. 143782-23-4. Molecular formula: C9H3F3N2S. Mole weight: 228.20. |  |
| Enzalutamide Impurity B | An impurity of Enzalutamide. Enzalutamide is an androgen-receptor (AR) antagonist in LNCaP cells. Synonyms: 4-BroMo-2-fluoro-N-MethylbenzaMide. Grade: > 95%. CAS No. 749927-69-3. Molecular formula: C8H7BrFNO. Mole weight: 232.05. | |
| Enzalutamide Impurity C | An impurity of Enzalutamide. Enzalutamide is an androgen-receptor (AR) antagonist in LNCaP cells. Synonyms: Methyl 4-broMo-2-fluorobenzoate. Grade: > 95%. CAS No. 179232-29-2. Molecular formula: C8H6BrFO2. Mole weight: 233.04. | |
| Enzastaurin | Enzastaurin is a protein kinase C beta inhibitor with 6- to 20-fold selectivity against PKCα, PKCγ and PKCε. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden. Synonyms: 3-(1-Methyl-1H-indol-3-yl)-4-(1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-1H-indol-3-yl)-1H-pyrrole-2,5-dione; LY-317615. CAS No. 170364-57-5. Molecular formula: C32H29N5O2. Mole weight: 515.617. | |
| EO 1428 | EO 1428 is a selective inhibitor of p38α and p38β2 MAP kinase, but displays no activity at p38γ, p38δ, ERK1/2 and JNK1. EO 1428 inhibits production of inflammatory cytokines including IL-8, TNF-α, IL-6, IL-1β and IL-10 (IC50 - 4, 5, 17, 30 and 74 nM, respectively) and acts against inflammation in murine models of acute and chronic dermatitis. Synonyms: EO-1428; EO 1428; EO1428; (2-Methylphenyl)-[4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl]methanone. Grade: ≥98% by HPLC. CAS No. 321351-00-2. Molecular formula: C20H16BrClN2O. Mole weight: 415.71. | |
| EOAI3402143 | EOAI3402143 is a deubiquitinase (DUB) inhibitor that dose-dependently inhibits Usp9x, Usp24 and Usp5 activity. Synonyms: EOAI3402143; 1699750-95-2; (E)-2-Cyano-3-(3,6-dichloropyridin-2-yl)-N-(1-(4-(2-morpholinoethoxy)phenyl)butyl)acrylamide; morpholin-4-yl-ethoxy)-phenyl]-butyl}-acrylamide; (2E)-2-cyano-3-(3,6-dichloropyridin-2-yl)-N-(1-{4-[2-(morpholin-4-yl)ethoxy]phenyl}butyl)prop-2-enamide; (E)-2-cyano-3-(3,6-dichloropyridin-2-yl)-N-[1-[4-(2-morpholin-4-ylethoxy)phenyl]butyl]prop-2-enamide; CHEMBL4287357; SCHEMBL16647263; SCHEMBL17986430; IIKVQQNZHGBYGQ-KNTRCKAVSA-N; EX-A3825; ZSC75095; MFCD31692368; s6877; AKOS040733108; MS-29351; D81247; EN300-23308289; Z3476101194; 2-Cyano-3-(3,6-dichloro-pyridin-2-yl)-N-{1-[4-(2-; 2-Cyano-3-(3,6-dichloro-pyridin-2-yl)-N-{1-[4-(2- morpholin-4-yl-ethoxy)-phenyl]-butyl}-acrylamide. CAS No. 1699750-95-2. Molecular formula: C25H28Cl2N4O3. Mole weight: 503.42. | |
| EP-024297 | EP-024297 is a novel agonist of farnesoid X receptor (FXR). Study in Chinese hamster ovary cells showed that it is 20000-fold more potent than obeticholic acid (OCA). EP-024297 is selective for FXR over TGR5. It promisingly becomes a new treatment of NASH. Uses: The potential treatment of nash. Synonyms: EP-024297; EP 024297; EP024297. | |
| EP1013 | EP1013 is a broad-spectrum caspase selective inhibitor with no observed toxicity in rodents, used in the research of type 1 diabetes. Synonyms: EP 1013; EP-1013; (3S)-5-fluoro-3-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]-4-oxopentanoic acid; benzyloxycarbonyl-valyl-aspartic acid fluoromethyl ketone; EP1013; F573 compound; MX1013; N-benzyloxycabonyl-Val Asp-fluoromethyl ketone; Z-VD-FMK; zVD-FMK. CAS No. 223568-55-6. Molecular formula: C18H23FN2O6. Mole weight: 382.38. | |
| EP1-antanoist-1 | A EP1 antagonist (pKi= 7.54) (pIC50= 8.5). Synonyms: 1-[[5-Bromo-2-[[(2,4-dichlorophenyl)methyl]oxy]phenyl]methyl]-5-methyl-1H-pyrazole-3-carboxylic acid. CAS No. 851204-35-8. Molecular formula: C19H15BrCl2N2O3. Mole weight: 470.14. | |
| EP2 receptor antagonist-1 | EP2 receptor antagonist-1 is a potent and agonist dependent allosteric prostaglandin EP2 receptor antagonist. It shows anti-inflammatory effects. CAS No. 848920-08-1. Molecular formula: C24H22N4O5. Mole weight: 446.46. | |
| EP4 receptor antagonist 1 | EP4 receptor antagonist 1 is an antagonist of the prostaglandin E2 (PGE2) receptor EP4 that has an IC50 value of 6.1 nM. Synonyms: (S,E)-4-(1-(4-(prop-1-en-1-yl)-1-(4-(trifluoromethyl)benzyl)-1H-1,2,3-triazole-5-carboxamido)ethyl)benzoic acid. CAS No. 2287259-07-6. Molecular formula: C23H21F3N4O3. Mole weight: 458.43. | |
| EP4 receptor antagonist 2 | EP4 receptor antagonist 2 (compound 2-13) is a potent antagonist of EP4 receptor with an IC50 of 7.8 nM. Synonyms: EP4 receptor antagonist; 21965316-82-8; 4-(4-Cyano-2-((2'R,4S)-6-(isopropylcarbamoyl)spiro[chromane-4,1'-cyclopropane]-2'-carboxamido)phenyl)butanoic acid; SCHEMBL17922637BDBM285467. CAS No. 1965316-82-8. Molecular formula: C27H29N3O5. Mole weight: 475.54. | |
| EP4 receptor antagonist 3 | EP4 receptor antagonist 3 is a potent antagonist of EP4 receptor. EP4 receptor antagonist 3 can be used for the reseacrh of EP4 receptor-mediated diseases, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis and cancer. CAS No. 1207954-34-4. Molecular formula: C26H21F3N2O3S. Mole weight: 498.52. | |
| EP6 | EP6 is a 5-lipoxygenase (5-LO) inhibitor. Synonyms: EP-6; EP 6. Grade: ≥98% by HPLC. CAS No. 1353567-32-4. Molecular formula: 24H30N4O. Mole weight: 390.5. | |
| EPAC 5376753 | EPAC 5376753 is an allosterically inhibitor of Epac which inhibits Epac1 with an IC50 of 4 μM in Swiss 3T3 cells. Synonyms: 5-{[5-(2,4-dichlorophenyl)furan-2-yl]methylidene}-2-thioxodihydropyrimidine-4,6(1H,5H)-dione. CAS No. 302826-61-5. Molecular formula: C15H8Cl2N2O3S. Mole weight: 367.21. | |
| Epacadostat | Epacadostat, also known as INCB024360 or INCB24360, is a potent and selective IDO1 inhibitor with IC50 of 71.8 nM±17.5 nM, with potential immunomodulating and antineoplastic activities. It has been shown to promote T and natural killer-cell growth, to increase IFN-γ production, and to reduce conversion to regulatory T (Treg)-like cells in a coculture system of human allogeneic lymphocytes with either dendritic cells or tumor cells. Synonyms: IDO inhibitor 1; 1,2,5-Oxadiazole-3-carboximidamide, 4-[[2-[(aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-, [C(Z)]-; [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide; ICBN 24360; ICBN-24360; ICBN24360; INCB 024360; INCB024360; INCB-024360. Grade: ≥95%. CAS No. 1204669-58-8. Molecular formula: C11H13BrFN7O4S. Mole weight: 438.23. | |
| Epalrestat | Epalrestat is an aldose reductase inhibitor with IC50 of 72 nM. Uses: Enzyme inhibitors. Synonyms: Kinedak; ONO-2235; ONO 2235; ONO2235; Sorbistat; (5Z)-5-[(2E)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid; 3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (Z,E)-; 3-Thiazolidineacetic acid, 5-[(2E)-2-methyl-3-phenyl-2-propenylidene]-4-oxo-2-thioxo-, (5Z)-; 2-[(Z)-5-((E)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl]acetic acid; Eabeth. Grade: >98%. CAS No. 82159-09-9. Molecular formula: C15H13NO3S2. Mole weight: 319.40. | |
| Epalrestat Dimer | A dimer impurity of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: Dimer of 5Z-[(2E)-2-methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid. Grade: >95%. Molecular formula: C30H26N2O6S4. Mole weight: 638.81. | |
| Epalrestat (E,E)-Isomer | A stereoisomer of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: (5E)-5-[(2E)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid; 3-Thiazolidineacetic acid, 5-[(2E)-2-methyl-3-phenyl-2-propenylidene]-4-oxo-2-thioxo-, (5E)-; 2-((E)-5-((E)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid. Grade: >95%. CAS No. 863988-85-6. Molecular formula: C15H13NO3S2. Mole weight: 319.40. | |
| Epalrestat (E,Z)-Isomer | A stereoisomer of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: (5E)-5-[(2Z)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid; 3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (E,Z)-; 3-Thiazolidineacetic acid, 5-[(2Z)-2-methyl-3-phenyl-2-propenylidene]-4-oxo-2-thioxo-, (5E)-; (E,Z)-5-(2-Methyl-3-phenyl-2-propen-1-ylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid; 2-((E)-5-((Z)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid. Grade: >95%. CAS No. 124782-64-5. Molecular formula: C15H13NO3S2. Mole weight: 319.40. | |
| Epalrestat (Z,Z)-Isomer | It is a stereoisomer of Epalrestat, an aldose reductase inhibitor with IC50 of 72 nM. Synonyms: 2-[(5Z)-5-[(2Z)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid; (5Z)-5-[(2Z)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid; 3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (Z,Z)-; 3-Thiazolidineacetic acid, 5-[(2Z)-2-methyl-3-phenyl-2-propenylidene]-4-oxo-2-thioxo-, (5Z)-; (Z,Z)-5-(2-Methyl-3-phenyl-propenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid. Grade: >95%. CAS No. 124782-63-4. Molecular formula: C15H13NO3S2. Mole weight: 319.40. | |
| EP Chlorpheniramine Maleate Impurity A (2HCl salt form) | An impurity of Chlorpheniramine. Chlorpheniramine is an antihistamine used to prevent symptoms of allergy. It acts via inhibiting histamine produced during anaphylaxis. Synonyms: 2-(4-Chlorophenyl)-4-(dimethylamino)-2-(2-(dimethylamino)ethyl)butanenitrile; 2-(4-Chlorophenyl)-4-(dimethylamino)-2-[2-(dimethylamino)ethyl]butanenitrile dihydrochloride. Grade: 95%. Molecular formula: C16H26Cl3N3. Mole weight: 366.761. | |
| Epcoritamab | Epcoritamab is a bispecific T-cell engager (BiTE) antibody that targets CD3 and CD20. Epcoritamab previously demonstrated potent antitumor activity in dose escalation across B-cell non-Hodgkin lymphoma subtypes. Synonyms: GEN-3013; GEN 3013; GEN3013. Grade: 95%. CAS No. 2134641-34-0. | |
| Epelsiban | Epelsiban is an oxytocin receptor antagonist under the developement of GlaxoSmithKline. It has high affinity for the oxytocin receptor (Ki = 0.13 nM) with >31,000-fold selectivity over the related vasopressin receptors. No development was reported about Phase II clinical tirals for the treatment of premature ejaculation. Uses: Premature ejaculation. Synonyms: GSK-557296; GSK 557296; GSK557296; GSK-557,296-B; (3R,6R)-6-((S)-sec-butyl)-3-(2,3-dihydro-1H-inden-2-yl)-1-((R)-1-(2,6-dimethylpyridin-3-yl)-2-morpholino-2-oxoethyl)piperazine-2,5-dione. Grade: 98%. CAS No. 872599-83-2. Molecular formula: C30H38N4O4. Mole weight: 518.65. | |
| Epelsiban besylate | This active molecular, also known as GSK-557296B, is a selective, sub-nanomolar (Ki=0.13 nM) oxytocin receptor antagonist with more than 30000-fold selectivity over the related vasopressin receptors. Uses: Adenomyosis;infertility; premature ejaculation. Synonyms: GSK557296B; GSK-557296B; (3R,6R)-3-(2,3-Dihydro-1H-inden-2-yl)-1-((1R)-1-(2,6-dimethylpyridin-3-yl)-2-(morpholin-4-yl)-2-oxoethyl)-6-((1S)-1-methylpropyl)piperazine-2,5-dione monobenzenesulfonate. Grade: 98%. CAS No. 1159097-48-9. Molecular formula: C36H44N4O7S. Mole weight: 676.83. | |
| Eperezolid | Eperezolid(PNU-100592) is a oxazolidinone antibacterial agent, Eperezolid demonstrated good in vitro inhibitory activity, regardless of methicillin susceptibility for staphylococci(MIC90= 1-4 mg/ml). Synonyms: PNU-100592; PNU100592; PNU 100592. Grade: >98%. CAS No. 165800-04-4. Molecular formula: C18H23FN4O5. Mole weight: 394.4. | |
| Eperisone HCl | Eperisone relaxes both skeletal muscles and vascular smooth muscles. Uses: Anticonvulsants. Synonyms: 1-(4-Ethylphenyl)-2-methyl-3-(1-piperidinyl)-1-propanone Hydrochloride. Grade: > 95%. CAS No. 56839-43-1. Molecular formula: C17H25NO. HCl. Mole weight: 259.39 36.46. | |
| Epertinib | Epertinib, also known as S-222611, is a potent, oral, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively, currently under trials in patients with solid tumours. It also inhibited intracellular kinase activity and the growth of EGFR-expressing and HER2-expressing cancer cells. Synonyms: Epertinib; S-22611; S22611; S 22611; (R,Z)-1-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)but-2-yn-1-one O-morpholin-3-ylmethyl oxime; Epertinib; S-222611; S222611; S 222611; 2-Butyn-1-one, 1-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)-, O-((3R)-3-morpholinylmethyl)oxime, (1Z)-; N-{3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl}- 6-[(1Z)-N-{[(3R)-morpholin-3-yl]methoxy}but- 2-ynimidoyl]quinazolin-4-amine. CAS No. 908305-13-5. Molecular formula: C30H27ClFN5O3. Mole weight: 559.178. | |
| Epertinib hydrochloride | Epertinib, also known as S-222611, is a potent, oral, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, currently under trials in patients with solid tumours. It also inhibited intracellular kinase activity and the growth of EGFR-expressing and HER2-expressing cancer cells. Synonyms: Epertinib HCl; S-222611 hydrochloride; S-222611 HCl. CAS No. 2071195-74-7. Molecular formula: C30H28Cl2FN5O3. Mole weight: 596.48. | |
| Epetirimod | Epetirimod is a small-molecule immune-response modifier intended for the topical treatment of cervical human papilloma virus (HPV) infection and cervical dysplasia. Synonyms: Epetirimod; 227318-71-0; UNII-9P5MH9F521; Epetirimod [USAN:INN]; 851A; S-30563; 9P5MH9F521; 1-(2-Methylpropyl)-1H-imidazo(4,5-c)(1,5)naphthyridin-4-amine; 1-(2-methylpropyl)imidazo[4,5-c][1,5]naphthyridin-4-amine; 1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine; 851-A; 1H-Imidazo(4,5-c)(1,5)naphthyridin-4-amine, 1-(2-methylpropyl)-; S 30563; Epetirimod [USAN]; EPETIRIMOD [INN]; Epetirimod (INN/USAN); SCHEMBL544542; CHEMBL2103807; DTXSID20177268; UCPMSMNKGXUFCC-UHFFFAOYSA-N; AKOS040751696; TS-08718; D08911; Q27272855. Grade: >98%. CAS No. 227318-71-0. Molecular formula: C23H18F4N6O2S. Mole weight: 518.5. | |
| Epetraborole HCl | This active molecular is a selective leucyl-tRNA synthetase inhibitor under the development of Anacor Pharmaceuticals and GlaxoSmithKline as a novel boron-containing antibiotic. Epetraborole was applicated in treatment of infections caused by multidrug-resistant Gram-negative pathogens. All Clostridium perfringens strains had Epetraborole MICs of >32 μg/ml. In Oct 2012, Phase-II for Urinary tract infections in Russia was discontinued. In Mar 2013, Phase-II for Gram-negative infections in USA was Suspended. Uses: Urinary tract infections;gram-negative infections. Synonyms: UNII-MM0NZY12FA; MM0NZY12FA; SCHEMBL1980656; CHEMBL3527377; 3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol; hydrochloride; AN-3365; GSK-052; AN 3365; GSK 052; AN3365; GSK052. Grade: 98%. CAS No. 1234563-16-6. Molecular formula: C11H17BClNO4. Mole weight: 373.52. | |
| EPI-001 | EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ?6 μM and a selective PPAR-gamma modulator. Synonyms: EPI001; EPI 001. Grade: 98%. CAS No. 227947-06-0. Molecular formula: C21H27ClO5. Mole weight: 394.89. | |
| Epi-(26R) Vancomycin B | Epi-(26R) Vancomycin B is the monohydrochloride of Vancomycin. Vancomycin is a glycopeptide antibiotic for the treatment of gram-positive bacteria. Vancomycin exhibits an antibacterial effect by inhibiting bacterial cell wall synthesis. Uses: Anti-bacterial agents. Synonyms: Vancomycin Monohydrochloride; Lyphocin Monohydrochloride; Meek Monohydrochloride; Vancocin Monohydrochloride; Vancocine Monohydrochloride; Vancocyn Monohydrochloride; Vancor Monohydrochloride. CAS No. 197638-25-8. Molecular formula: C66H75Cl2N9O24 HCl. Mole weight: 1485.71. | |
| Epiallopregnanolone | Epiallopregnanolone, a metabolite of progesterone, is a novel derivative of the steroid Dehydroepiandrosterone (DHEA). Epiallopregnanolone is a 3β-isomer of allopregnanolone. Epiallopregnanolone is inactive as a GABAA receptor modulator and is used as a control substance to examine GABA neurotransmission. Synonyms: 5α-Pregnan-20-one; 3β,21-dihydroxy-5α-Pregnan-20-one; 3β,5α-Tetrahydrodeoxycorticosterone; 3β,5α-Tetrahydroprogesterone; 2-hydroxy-1-[(3S,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone. Grade: ≥95%. CAS No. 567-01-1. Molecular formula: C21H34O3. Mole weight: 334.5. | |
| Epiandrosterone b-D-glucuronide | Epiandrosterone is an innate steroid hormone, and Epiandrosterone b-D-glucuronide manifests as a glucuronide conjugate. Predominantly employed in the realm of biomedical inquiry, it is used to unravel the intricate web of Epiandrosterone's metabolism and excretion within the corporeal domain. Synonyms: (3b,5a)-17-Oxoandrostan-3-yl b-D-glucopyranosiduronic acid; 17-Oxo-5a-androstan-3b-yl b-D-glucopyranosiduronic acid; 17-Oxo-5a-androstan-3b-yl b-D-glucosiduronic acid. CAS No. 4271-00-5. Molecular formula: C25H38O8. Mole weight: 466.56. | |
| Epibatidine | (±)-Epibatidine is a potent nicotinic agonist (Ki = 0.02 and 233 nM for α4β2 and α7 nicotinic receptors, respectively). Uses: Analgesic. Synonyms: Epibatidine; (±)-exo-2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1.]heptane. CAS No. 140111-52-0. Molecular formula: C11H13ClN2. Mole weight: 208.69. | |
| Epiblastin A | Epiblastin A is a Casein Kinase 1 (CK1) inhibitor. It converts epiblast stem cells (EpiSC) into embryonic stem cells (ESC) and enhances ESC self-renewal. Synonyms: Epiblastin A - Bio-X. Grade: >98%. CAS No. 16470-02-3. Molecular formula: C12H10ClN7. Mole weight: 287.711. | |
| Epiboxidine hydrochloride | Epiboxidine is a potent nicotinic acetylcholine receptor agonist. An analog of epibatidine. Synonyms: exo-2-(3-Methyl-5-isoxazolyl)-7-azabicyclo[2.2.1]heptane hydrochloride. CAS No. 188895-96-7. Molecular formula: C10H15ClN2O. Mole weight: 214.69. | |
| Epicellobiose | Epicellobiose. Synonyms: 4-O-β-D-Glucopyranosyl-D-mannopyranose; Mannopyranose, 4-O-β-D-glucopyranosyl-, D-; beta-D-glucosyl-(1->4)-D-mannopyranose; beta-D-glucopyranosyl-(1->4)-D-mannopyranose; D-Glucosyl-D-mannose; (3S,4R,5S,6R)-6-(Hydroxymethyl)-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triol. Grade: ≥95%. CAS No. 27452-49-9. Molecular formula: C12H22O11. Mole weight: 342.30. | |
| Epichlorohydrin-[d5] | Epichlorohydrin-[d5]. Synonyms: Epichlorohydrin-d5; Oxirane-d3, (chloromethyl-d2)-; Oxirane-2,2,3-d3, 3-(chloromethyl-d2)-. Grade: 98% atom D. CAS No. 69533-54-6. Molecular formula: C3ClD5O. Mole weight: 97.56. | |
| Epidermal Growth Factor | Epidermal Growth Factor (EGF) is a protein that stimulates the proliferation of different types of cells via binding to its receptor EGFR. EGF has been found in many human tissues such as submandibular gland and parotid gland. Synonyms: EGF. Molecular formula: C257H381N73O83S7. Mole weight: 6046. | |
| Epi-Galantamine | Epi-Galantamine is a selective acetylcholinesterase inhibitor. Synonyms: (4aS,6S,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol; 2-Epigalanthamine; (-)-Epigalanthamine; SPH 1068; 3-Epigalanthamine; Galantamine Impurity B. Grade: > 95%. CAS No. 1668-85-5. Molecular formula: C17H21NO3. Mole weight: 287.36. | |
| Epi-Galantamine N-Oxide | Introducing Epi-Galantamine N-Oxide is an intriguing compound extensively employed in the research of neurodegenerative afflictions, most notably Alzheimer's disease. This remarkable substance optimizes cognitive prowess and memory retention by acting as a potent acetylcholinesterase inhibitor, thereby bolstering the cerebral abundance of acetylcholine. Synonyms: (4aS,6S,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol 11-Oxide. Grade: > 95%. CAS No. 366485-18-9. Molecular formula: C17H21NO4. Mole weight: 303.36. | |
| Epigallocatechin 3-O-(3-O-Methyl)-Gallate | (-)-EGCG-3''-O-Me is a compound of the flavonoid class found in the leaves of Camellia sinensis. It exhibits antioxidative, antiallergic and anti-inflammatory effects. Synonyms: Epigallocatechin 3-O-(3-O-methyl)gallate; [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4-dihydroxy-5-methoxybenzoate. Grade: >98%. CAS No. 83104-87-4. Molecular formula: C23H20O11. Mole weight: 472.402. | |
| epi-Inositol | epi-Inositol is a multifunctional natural compound for the research of insulin resistance and polycystic ovary syndrome (PCOS) because of its exceptional insulin-sensitizing properties. Uses: A growth factor in many plants and animals; used as a nutritional supplement; an isomer of glucose that has traditionally been considered to be a b vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. Synonyms: inositol; myo-inositol; Scyllo-inositol; epi-Inositol; Muco-Inositol; Allo-inositol; i-Inositol; meso-Inositol; Neo-inositol; D-chiro-Inositol; 1L-Chiro-inositol; D-(+)-chiro-Inositol; cis-Inositol; 1D-Chiro-inositol; Myoinositol; Scyllitol; Cyclohexane-1,2,3,4,5,6-hexaol; (1r,2r,3r,4r,5r,6r)-cyclohexane-1,2,3,4,5,6-hexol; (1r,2R,3S,4r,5R,6S)-cyclohexane-1,2,3,4,5,6-hexol; 1,3,5/2,4,6-Hexahydroxycyclohexane; (1R,2R,3R,4R,5S,6S)-Cyclohexane-1,2,3,4,5,6-hexaol; 1-L-chiro-Inositol; Inositol, D-chiro-; (+)-Chiro-Inositol. CAS No. 488-58-4. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| epi-Kifunensine | epi-Kifunensine is a catalytically potent inhibitor of α-mannosidase I enzyme. By illuminating the multifaceted functions of α-mannosidase I in intricate protein glycosylation pathways, this product emerges as an indispensable tool fostering profound comprehension of glycoprotein biosynthesis. Moreover, its salience extends to study advancements targeting α-mannosidase I dysfunction-driven maladies, notably lysosomal storage disorders. Synonyms: (5R,6R,7S,8R,8aR)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione. Molecular formula: C8H12N2O6. Mole weight: 232.19. | |
| epi-Lactose | epi-Lactose is an epimer of Lactose and is also known to exhibit prebiotic properties. Synonyms: 4-O-β-D-galactopyranosyl-D-mannose; 4-O-β-D-galactopyranosyl-mannose; Epilactose. Grade: 98%. CAS No. 50468-56-9. Molecular formula: C12H22O11. Mole weight: 342.30. | |
| epi-Lactose-1-13C | Isotope labelled epi-Lactose is an epimer of Lactose and is also known to exhibit prebiotic properties. Synonyms: 4-O-β-D-galactopyranosyl-D-mannose-1-13C; 4-O-β-D-galactopyranosyl-mannose-1-13C; Epilactose-1-13C. Molecular formula: C11[13C]H21O11. Mole weight: 342.28. | |
| epi-Lincomycin-2,7-dipalmitate | epi-Lincomycin-2,7-dipalmitate is an impurity of Clindamycin, which is a semi-synthetic antibiotic prepared from Lincomycin. Molecular formula: C51H95NO8S. Mole weight: 882.36. | |
| Epilotaustralin Tetraacetate | Epilotaustralin Tetraacetate is an intermediate in the synthesis of (R)-Lotaustralin, which is a bioactive constituent of Chinese natural medicines. Synonyms: Epilotaustralin Tetraacetate (Ester). CAS No. 27749-92-4. Molecular formula: C19H27NO10. Mole weight: 429.42. | |
| Epimaltose | Epimaltose. Synonyms: 4-O-α-D-Glucopyranosyl-D-mannose; (2S,3R,4R,5R)-2,3,5,6-Tetrahydroxy-4-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal; alpha-D-glucosyl-(1->4)-aldehydo-D-mannose; alpha-D-glucopyranosyl-(1->4)-aldehydo-D-mannose; 4-O-α-D-Glucopyranosyl-D-mannopyranose. Grade: ≥95%. CAS No. 70832-27-8. Molecular formula: C12H22O11. Mole weight: 342.30. | |
| Epimer of Doxorubicin Impurity B | Epimer of Doxorubicin Impurity B is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: (8S,10S)-10-(((2R,4S,5R,6R)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(2-bromo-1,1-dimethoxyethyl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione. Molecular formula: C29H34BrNO11. Mole weight: 652.49. | |
| Epimer of Doxorubicin Impurity C | Epimer of Doxorubicin Impurity C is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: (8S,10S)-10-(((2R,4S,5R,6R)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(2-bromoacetyl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione. Molecular formula: C27H28BrNO10. Mole weight: 606.43. | |
| epi-Milbemycin A4 | epi-Milbemycin A4 is a compound used in studying parasitic infections across diverse animal species. Its remarkable efficacy extends to eradicating an array of parasites, encompassing the formidable heartworms, roundworms and hookworms. Synonyms: DTXSID10860632; (2S,6R,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-25-ethyl-milbemycin B. CAS No. 160081-46-9. Molecular formula: C32H46O7. Mole weight: 542.70. | |
| Epi-N-Acetyl-lactosamine | Epi-N-Acetyl-lactosamine is a paramount compound exploited for studying glycosylation procedures. Its prowess lies in the emulation of intricate carbohydrate configurations, thereby endowing elucidations into the functionalities of glycans across diverse biological frameworks. Synonyms: Gala1-4GlcNAc; 2-Acetamido-2-deoxy-4-O-a-D-galactopyranosyl-D-glucopyranose. CAS No. 205380-69-4. Molecular formula: C14H25NO11. Mole weight: 383.35. | |
| Epinastine | Epinastine is a second-generation antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. It is highly selective for the H1 receptor and does not cross the blood-brain-barrier. It shows a high affinity to H1-receptors in receptor binding studies in the guinea pig ileum. It inhibits histamine-induced reactions in the skin or the lung of rats, dogs and guinea pigs. It is able to displace specific [3H]NC-5Z binding at low concentrations in the locust nervous tissue. It antagonises octopamine-induced cAMP formation in the insect brain. It is effective in inhibiting not only Ca2+ uptake into lung mast cells in actively sensitized guinea pigs but also Ca2+ release from the intracellular Ca store of rat peritoneal mast cells exposed to both compound 48/80 and substance. It is produced by Allergan and marketed by Inspire in the United States. Uses: Epinastine is used in eye drops to treat allergic conjunctivitis. it is highly selective for the h1 receptor and does not cross the blood-brain-barrier. Synonyms: 9,13b-Dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepin-3- amine; 3-Amino-9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepine; Apinastine Base; WAL 801. Grade: >98%. CAS No. 80012-43-7. Molecular formula: C16H15N3. Mole weight: 249.31. | |
| Epinastine-13C-D3 HBr | Isotope labelled Epinastine HBr. Epinastine is a non-sedating ophthalmic antihistamine that antagonizes histamine H7 receptors and prevents the release of pro-inflammatory mediators from mast cells and eosinophils. Synonyms: 3-Amino-7-bromo-9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepine-13C-D3 HBr. Grade: > 95%. Molecular formula: C15[13C]H12N3D3·HBr. Mole weight: 253.32 80.91. | |
| Epinastine hydrobromide | Epinastine is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. Synonyms: (+/-)-3-amino-9,13b-dihydro-1h-dibenz[c,f]imidazo[1,5-a]azepine hydrobromide; Epinastine HBr. CAS No. 127786-29-2. Molecular formula: C16H15N3.HBr. Mole weight: 330.23. | |
| Epinastine hydrochloride | Epinastine hydrochloride is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. It is a potent, selective and orally active histamine H1 receptor antagonist that also inhibits IL-8 release and has antiallergic effects. Uses: Histamine h1 antagonists. Synonyms: 1H-Dibenz[c,f]imidazo[1,5-a]azepin-3-amine, 9,13b-dihydro-, hydrochloride (1:1); WAL801 hydrochloride; 9,13b-Dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepin-3-amine Hydrochloride; Alesion; Elestat; WAL 801CL; IH-Dibenz(c,f)imidazo(1,5-a)azepin-3-amine, 9,13b-dihydro-, monohydrochloride. Grade: >98%. CAS No. 108929-04-0. Molecular formula: C16H15N3.HCl. Mole weight: 285.77. | |
| Epinastine Related Compound A | An impurity of Epinastine. Epinastine is a non-sedating ophthalmic antihistamine that antagonizes histamine H5 receptors and prevents the release of pro-inflammatory mediators from mast cells and eosinophils. Synonyms: 6-Aminomethyl-5,6-dihydromorphanthridine. Grade: > 95%. CAS No. 41218-84-2. Molecular formula: C15H16N2. Mole weight: 224.31. | |
| Epinephrine 4-O-Sulfate Ester | A derivative of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Synonyms: 4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol 1-(Hydrogen Sulfate); 3,4-Dihydroxy-α-[(methylamino)methyl]benzyl Alcohol 4-(Hydrogen Sulfate); 1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, 1-(hydrogen sulfate); Benzyl alcohol, 3,4-dihydroxy-α-[(methylamino)methyl]-, 4-(hydrogen sulfate); Epinephrine-3-O-sulfate. Grade: ≥95%. CAS No. 21093-18-5. Molecular formula: C9H13NO6S. Mole weight: 263.27. | |
| Epinephrine Glucuronide | A metabolite of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Synonyms: β-D-Glucopyranosiduronic acid, 2-hydroxy-4-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenyl; 2-Hydroxy-4-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenyl β-D-glucopyranosiduronic acid; β-D-Glucopyranosiduronic acid, 2-hydroxy-4-[1-hydroxy-2-(methylamino)ethyl]phenyl, (R)-; L-Epinephrine β-D-Glucuronide. Grade: ≥95%. CAS No. 54964-61-3. Molecular formula: C15H21NO9. Mole weight: 359.33. | |
| Epinephrine Impurity 10 | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Molecular formula: C8H9NO4S. Mole weight: 215.23. | |
| Epinephrine Impurity 11 | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Molecular formula: C8H9NO4S. Mole weight: 215.23. | |
| Epinephrine Impurity 1 Sodium Salt | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. CAS No. 21093-14-1. Molecular formula: C9H12NO6SNa. Mole weight: 285.25. | |
| Epinephrine Impurity 2 DiHCl | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Molecular formula: C16H20Cl2N2O4. Mole weight: 375.25. | |
| Epinephrine Impurity 4 | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Synonyms: 1H-Indole-3-sulfonic acid, 2,3,5,6-tetrahydro-1-methyl-5,6-dioxo-; 2,3,5,6-Tetrahydro-1-methyl-5,6-dioxo-1H-indole-3-sulfonic acid; 3-Indolinesulfonic acid, 5,6-dihydro-1-methyl-5,6-dioxo-. CAS No. 94217-53-5. Molecular formula: C9H9NO5S. Mole weight: 243.24. | |
| Epinephrine Impurity 5 | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Molecular formula: C9H11NO5S. Mole weight: 245.25. | |
| Epinephrine Impurity 6 | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Molecular formula: C18H24N2O7S. Mole weight: 412.46. | |
| Epinephrine Impurity 7 | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Synonyms: 1H-Indole-3,5,6-triol, 2,3-dihydro-1-methyl-, (R)-. CAS No. 62322-82-1. Molecular formula: C9H11NO3. Mole weight: 181.19. | |
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